TY  - JOUR
AU  - Tsoukatou, Maria
AU  - Marechal, Jean Philippe
AU  - Hellio, Claire
AU  - Novaković, Irena T.
AU  - Tufegdzie, Srdan
AU  - Sladić, Dušan
AU  - Gasic, Miroslav J.
AU  - Clare, Anthony S.
AU  - Vagias, Constantinos
AU  - Roussis, Vassilios
PY  - 2007
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/840
AB  - The sesquiterpene hydroquinone avarol (1) was isolated from the marine sponge Dysidea avara, whereas the corresponding quitione, avarone (2), was obtained by oxidation of avarol, and the significantly more lipophilic compounds [3 '-(P-chlorophenyl)avarone (3), 3 ',4 '-ethylenedithioavarone (4), 4 '-isopropylthioavarone (5), 4 '-tertbutylthioavarone (6), 4 '-propylthioavarone (7), 4 '-octylthioavarone (8)] were obtained by nucleophilic addition of thiols or p-chloroaniline to avarone. All these compounds were tested, at concentrations ranging from 0.5 to 50 mu g/mL, for their effect on the settlement of the cyprid stage of Balanus amphitrite, for toxicity to both nauplii and cyprids and for their growth inhibitory activity on marine bacteria (Cobetia marina, Marinobacterium stanieri, Vibrio fischeri and Pseudoalteromonas haloplanktis) and marine fungi (Halosphaeriopsis mediosetigera, Asteromyces cruciatus, Lulworthia uniseptata and Monodictys pelagica).
PB  - Mdpi Ag, Basel
T2  - Molecules
T1  - Evaluation of the activity of the sponge metabolites avarol and avarone and their synthetic derivatives against fouling micro- and macroorganisms
VL  - 12
IS  - 5
SP  - 1022
EP  - 1034
DO  - 10.3390/12051022
ER  - 

@article{
author = "Tsoukatou, Maria and Marechal, Jean Philippe and Hellio, Claire and Novaković, Irena T. and Tufegdzie, Srdan and Sladić, Dušan and Gasic, Miroslav J. and Clare, Anthony S. and Vagias, Constantinos and Roussis, Vassilios",
year = "2007",
abstract = "The sesquiterpene hydroquinone avarol (1) was isolated from the marine sponge Dysidea avara, whereas the corresponding quitione, avarone (2), was obtained by oxidation of avarol, and the significantly more lipophilic compounds [3 '-(P-chlorophenyl)avarone (3), 3 ',4 '-ethylenedithioavarone (4), 4 '-isopropylthioavarone (5), 4 '-tertbutylthioavarone (6), 4 '-propylthioavarone (7), 4 '-octylthioavarone (8)] were obtained by nucleophilic addition of thiols or p-chloroaniline to avarone. All these compounds were tested, at concentrations ranging from 0.5 to 50 mu g/mL, for their effect on the settlement of the cyprid stage of Balanus amphitrite, for toxicity to both nauplii and cyprids and for their growth inhibitory activity on marine bacteria (Cobetia marina, Marinobacterium stanieri, Vibrio fischeri and Pseudoalteromonas haloplanktis) and marine fungi (Halosphaeriopsis mediosetigera, Asteromyces cruciatus, Lulworthia uniseptata and Monodictys pelagica).",
publisher = "Mdpi Ag, Basel",
journal = "Molecules",
title = "Evaluation of the activity of the sponge metabolites avarol and avarone and their synthetic derivatives against fouling micro- and macroorganisms",
volume = "12",
number = "5",
pages = "1022-1034",
doi = "10.3390/12051022"
}

Tsoukatou, M., Marechal, J. P., Hellio, C., Novaković, I. T., Tufegdzie, S., Sladić, D., Gasic, M. J., Clare, A. S., Vagias, C.,& Roussis, V.. (2007). Evaluation of the activity of the sponge metabolites avarol and avarone and their synthetic derivatives against fouling micro- and macroorganisms. in Molecules
Mdpi Ag, Basel., 12(5), 1022-1034.
https://doi.org/10.3390/12051022

Tsoukatou M, Marechal JP, Hellio C, Novaković IT, Tufegdzie S, Sladić D, Gasic MJ, Clare AS, Vagias C, Roussis V. Evaluation of the activity of the sponge metabolites avarol and avarone and their synthetic derivatives against fouling micro- and macroorganisms. in Molecules. 2007;12(5):1022-1034.
doi:10.3390/12051022 .

Tsoukatou, Maria, Marechal, Jean Philippe, Hellio, Claire, Novaković, Irena T., Tufegdzie, Srdan, Sladić, Dušan, Gasic, Miroslav J., Clare, Anthony S., Vagias, Constantinos, Roussis, Vassilios, "Evaluation of the activity of the sponge metabolites avarol and avarone and their synthetic derivatives against fouling micro- and macroorganisms" in Molecules, 12, no. 5 (2007):1022-1034,
https://doi.org/10.3390/12051022 . .