TY  - JOUR
AU  - Stanimirović, Bojana
AU  - Vujović, Dragan
AU  - Pejin, Boris
AU  - Popović-Djordjević, Jelena
AU  - Maletić, Radojka
AU  - Raičević, Petar
AU  - Tešić, Živoslav Lj.
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/329
AB  - The elemental profile of the leaf samples of three Cabernet Franc clone candidates recently developed in Serbia (Nos. 02, 010 and 012) obtained in the last phase of clonal selection was examined within this study by ICP-OES. Optimal content of Al, Fe, Cu and Zn, the metals well known for their links with a number of neurodegenerative disorders including Alzheimer’s disease, has actually highlighted the potential of the leaf sample No. 10 to afford a novel food supplement of natural origin possessing well balanced metal ingredients. Furthermore, lower content of some other elements (Cr, Mn, Ni and Pb) thoroughly supports such a claiming. Finally, the most favourable K/Na ratio observed for the aforementioned sample points out its likely cardioprotectivity. However, two other Cabernet Franc clone candidates might also be recommended for breeding in the same or similar viticultural conditions, since all obtained values were below toxic ones for human consumption. © 2018 Informa UK Limited, trading as Taylor & Francis Group
T2  - Natural Product Research
T1  - A contribution to the elemental profile of the leaf samples of newly developed Cabernet Franc varieties
SP  - 1
EP  - 5
DO  - 10.1080/14786419.2018.1457671
ER  - 

@article{
author = "Stanimirović, Bojana and Vujović, Dragan and Pejin, Boris and Popović-Djordjević, Jelena and Maletić, Radojka and Raičević, Petar and Tešić, Živoslav Lj.",
year = "2018",
abstract = "The elemental profile of the leaf samples of three Cabernet Franc clone candidates recently developed in Serbia (Nos. 02, 010 and 012) obtained in the last phase of clonal selection was examined within this study by ICP-OES. Optimal content of Al, Fe, Cu and Zn, the metals well known for their links with a number of neurodegenerative disorders including Alzheimer’s disease, has actually highlighted the potential of the leaf sample No. 10 to afford a novel food supplement of natural origin possessing well balanced metal ingredients. Furthermore, lower content of some other elements (Cr, Mn, Ni and Pb) thoroughly supports such a claiming. Finally, the most favourable K/Na ratio observed for the aforementioned sample points out its likely cardioprotectivity. However, two other Cabernet Franc clone candidates might also be recommended for breeding in the same or similar viticultural conditions, since all obtained values were below toxic ones for human consumption. © 2018 Informa UK Limited, trading as Taylor & Francis Group",
journal = "Natural Product Research",
title = "A contribution to the elemental profile of the leaf samples of newly developed Cabernet Franc varieties",
pages = "1-5",
doi = "10.1080/14786419.2018.1457671"
}

Stanimirović, B., Vujović, D., Pejin, B., Popović-Djordjević, J., Maletić, R., Raičević, P.,& Tešić, Ž. Lj.. (2018). A contribution to the elemental profile of the leaf samples of newly developed Cabernet Franc varieties. in Natural Product Research, 1-5.
https://doi.org/10.1080/14786419.2018.1457671

Stanimirović B, Vujović D, Pejin B, Popović-Djordjević J, Maletić R, Raičević P, Tešić ŽL. A contribution to the elemental profile of the leaf samples of newly developed Cabernet Franc varieties. in Natural Product Research. 2018;:1-5.
doi:10.1080/14786419.2018.1457671 .

Stanimirović, Bojana, Vujović, Dragan, Pejin, Boris, Popović-Djordjević, Jelena, Maletić, Radojka, Raičević, Petar, Tešić, Živoslav Lj., "A contribution to the elemental profile of the leaf samples of newly developed Cabernet Franc varieties" in Natural Product Research (2018):1-5,
https://doi.org/10.1080/14786419.2018.1457671 . .

TY  - DATA
AU  - Stanimirović, Bojana
AU  - Popović-Đorđevic, Jelena
AU  - Pejin, Boris
AU  - Maletić, Radojka
AU  - Vujović, Dragan
AU  - Raičević, Petar
AU  - Tešić, Živoslav Lj.
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3206
PB  - Elsevier Science Bv, Amsterdam
T2  - Scientia Horticulturae
T1  - Supplementary material for the article: Stanimirović, B.; Djordjević, J. P.; Pejin, B.; Maletić, R.; Vujović, D.; Raičević, P.; Tešić, Ž. Impact of Clonal Selection on Cabernet Franc Grape and Wine Elemental Profiles. Scientia Horticulturae 2018, 237, 74–80. https://doi.org/10.1016/j.scienta.2018.03.043
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3206
ER  - 

@misc{
author = "Stanimirović, Bojana and Popović-Đorđevic, Jelena and Pejin, Boris and Maletić, Radojka and Vujović, Dragan and Raičević, Petar and Tešić, Živoslav Lj.",
year = "2018",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Scientia Horticulturae",
title = "Supplementary material for the article: Stanimirović, B.; Djordjević, J. P.; Pejin, B.; Maletić, R.; Vujović, D.; Raičević, P.; Tešić, Ž. Impact of Clonal Selection on Cabernet Franc Grape and Wine Elemental Profiles. Scientia Horticulturae 2018, 237, 74–80. https://doi.org/10.1016/j.scienta.2018.03.043",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3206"
}

Stanimirović, B., Popović-Đorđevic, J., Pejin, B., Maletić, R., Vujović, D., Raičević, P.,& Tešić, Ž. Lj.. (2018). Supplementary material for the article: Stanimirović, B.; Djordjević, J. P.; Pejin, B.; Maletić, R.; Vujović, D.; Raičević, P.; Tešić, Ž. Impact of Clonal Selection on Cabernet Franc Grape and Wine Elemental Profiles. Scientia Horticulturae 2018, 237, 74–80. https://doi.org/10.1016/j.scienta.2018.03.043. in Scientia Horticulturae
Elsevier Science Bv, Amsterdam..
https://hdl.handle.net/21.15107/rcub_cherry_3206

Stanimirović B, Popović-Đorđevic J, Pejin B, Maletić R, Vujović D, Raičević P, Tešić ŽL. Supplementary material for the article: Stanimirović, B.; Djordjević, J. P.; Pejin, B.; Maletić, R.; Vujović, D.; Raičević, P.; Tešić, Ž. Impact of Clonal Selection on Cabernet Franc Grape and Wine Elemental Profiles. Scientia Horticulturae 2018, 237, 74–80. https://doi.org/10.1016/j.scienta.2018.03.043. in Scientia Horticulturae. 2018;.
https://hdl.handle.net/21.15107/rcub_cherry_3206 .

Stanimirović, Bojana, Popović-Đorđevic, Jelena, Pejin, Boris, Maletić, Radojka, Vujović, Dragan, Raičević, Petar, Tešić, Živoslav Lj., "Supplementary material for the article: Stanimirović, B.; Djordjević, J. P.; Pejin, B.; Maletić, R.; Vujović, D.; Raičević, P.; Tešić, Ž. Impact of Clonal Selection on Cabernet Franc Grape and Wine Elemental Profiles. Scientia Horticulturae 2018, 237, 74–80. https://doi.org/10.1016/j.scienta.2018.03.043" in Scientia Horticulturae (2018),
https://hdl.handle.net/21.15107/rcub_cherry_3206 .

TY  - JOUR
AU  - Stanimirović, Bojana
AU  - Popović-Đorđevic, Jelena
AU  - Pejin, Boris
AU  - Maletić, Radojka
AU  - Vujović, Dragan
AU  - Raičević, Petar
AU  - Tešić, Živoslav Lj.
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2141
AB  - Three Cabernet Franc (CF) clones (Nos. 02,010 and 012; not yet commercial) obtained in the last phase of clonal selection were examined within this study. Indeed, the content of 27 chemical elements in the vineyard soil along with CF grape and wine samples were determined by inductively coupled plasma - optical emission spectroscopy. The relative dependence of the selected elements in all samples were estimated using correlation matrices. While elemental profiles of both CF grape and wine samples were highly variable among the analysed clones, bioaccumulation factors (grape/soil) of Mg, Na and Sr were found to be specific for each single clone. Applying principal component analysis, the grape clones were differentiated among each other according to the content of 10 elements (Al, B, Ca, Cu, Fe, K, Mg, Mn, Na and Sr). Finally, hierarchical cluster analysis of CF grape and wine samples pointed out the similarity of the clones Nos. 010 and 012, since they were grouped within the same subcluster.
PB  - Elsevier Science Bv, Amsterdam
T2  - Scientia Horticulturae
T1  - Impact of clonal selection on Cabernet Franc Grape and wine elemental profiles
VL  - 237
SP  - 74
EP  - 80
DO  - 10.1016/j.scienta.2018.03.043
ER  - 

@article{
author = "Stanimirović, Bojana and Popović-Đorđevic, Jelena and Pejin, Boris and Maletić, Radojka and Vujović, Dragan and Raičević, Petar and Tešić, Živoslav Lj.",
year = "2018",
abstract = "Three Cabernet Franc (CF) clones (Nos. 02,010 and 012; not yet commercial) obtained in the last phase of clonal selection were examined within this study. Indeed, the content of 27 chemical elements in the vineyard soil along with CF grape and wine samples were determined by inductively coupled plasma - optical emission spectroscopy. The relative dependence of the selected elements in all samples were estimated using correlation matrices. While elemental profiles of both CF grape and wine samples were highly variable among the analysed clones, bioaccumulation factors (grape/soil) of Mg, Na and Sr were found to be specific for each single clone. Applying principal component analysis, the grape clones were differentiated among each other according to the content of 10 elements (Al, B, Ca, Cu, Fe, K, Mg, Mn, Na and Sr). Finally, hierarchical cluster analysis of CF grape and wine samples pointed out the similarity of the clones Nos. 010 and 012, since they were grouped within the same subcluster.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Scientia Horticulturae",
title = "Impact of clonal selection on Cabernet Franc Grape and wine elemental profiles",
volume = "237",
pages = "74-80",
doi = "10.1016/j.scienta.2018.03.043"
}

Stanimirović, B., Popović-Đorđevic, J., Pejin, B., Maletić, R., Vujović, D., Raičević, P.,& Tešić, Ž. Lj.. (2018). Impact of clonal selection on Cabernet Franc Grape and wine elemental profiles. in Scientia Horticulturae
Elsevier Science Bv, Amsterdam., 237, 74-80.
https://doi.org/10.1016/j.scienta.2018.03.043

Stanimirović B, Popović-Đorđevic J, Pejin B, Maletić R, Vujović D, Raičević P, Tešić ŽL. Impact of clonal selection on Cabernet Franc Grape and wine elemental profiles. in Scientia Horticulturae. 2018;237:74-80.
doi:10.1016/j.scienta.2018.03.043 .

Stanimirović, Bojana, Popović-Đorđevic, Jelena, Pejin, Boris, Maletić, Radojka, Vujović, Dragan, Raičević, Petar, Tešić, Živoslav Lj., "Impact of clonal selection on Cabernet Franc Grape and wine elemental profiles" in Scientia Horticulturae, 237 (2018):74-80,
https://doi.org/10.1016/j.scienta.2018.03.043 . .

TY  - JOUR
AU  - Stojanović, Srđan Đ.
AU  - Stanić, Dragana
AU  - Nikolić, Milan
AU  - Raicevic, S
AU  - Spasić, Mihajlo B.
AU  - Niketic, V
PY  - 2005
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/713
AB  - The peroxynitrite-induced nitration of manganese superoxide dismutase (MnSOD) tyrosine residue, which causes enzyme inactivation, is well established, This led to suggestions that MnSOD nitration and inactivation in vivo, detected in various diseases associated with oxidative stress and overproduction of nitric monoxide (NO), conditions which favor peroxynitrite formation, is also caused by peroxynitrite. However, our previous ill vitro study demonstrated that exposure of MnSOD to NO led to NO conversion into nitrosonium (NO+) and nitroxyl (NO-) species, which caused enzyme modifications and inactivation. Here it is reported that MnSOD is tyrosine nitrated upon exposure to NO, as well as that MnSOD nitration contributes to inactivation of the enzyme. Collectively, these observations provide a compelling argument supporting the generation of nitrating species in MnSOD exposed to NO and shed a new light on MnSOD tyrosine nitration and inactivation ill vivo. This may represent a novel mechanism by which MnSOD protects cell from deleterious effects associated with overproduction of NO. However, extensive MnSOD modification and inactivation associated with prolonged exposure to NO will amplify the toxic effects caused by increased cell superoxide and NO levels.
AB  - Dobro je poznato da peroksinitrit izaziva nitrovanje ostataka tirozina u mangan-superoksid- dismutazi (MnSOD) što dovodi do inaktivacije enzima. Pokazano je da nitrovanje i inaktivacija MnSOD-a nastaje u raznim bolestima za koje je karakteristič an oksidativni stres i povećana produkcija azot-monoksida (NO). Pošto se pri ovim uslovima očekuje nastajanje peroksinitrita predloženo je da peroksinitrit izaziva nitrovanje i inaktivaciju MnSOD in vivo. U našem prethodnom radu pokazali smo da MnSOD katalizuje transformaciju NO u nitrozonijum (NO+) i nitroksil (NO–) reaktivne vrste, te identifikovali neke od modifikacija molekula enzima koje pri tome nastaju izazivajući njegovu inaktivaciju. U ovom radu je pokazano da pri izlaganju MnSOD azot-monoksidu dolazi i do nitrovanja ostatka tirozina u molekulu enzima, što doprinosi njegovoj inaktivaciji. Ovi rezultati ukazuju da pri interakciji MnSOD sa NO dolazi do nastajanja nitrujućih vrsta, što baca novo svetlo na proces nitrovanja ostataka tirozina i inaktivaciju MnSOD in vivo. Ovo može da predstavlja novi mehanizam kojim MnSOD štiti ćeliju odštetnih efekata izazvanih hiperprodukcijom azot-monoksida. Međutim ekstenzivne modifikacije i inaktivacija MnSOD do kojih dolazi pri produženom izlaganju enzima NO, uvećaće toksične efekte izazvane povećanim koncentracijama superoksida i NO u ćeliji.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Manganese superoxide dismutase (MnSOD) catalyzes NO-dependent tyrosine residue nitration
T1  - Mangan-superoksid-dismutaza (MnSOD) katalizuje NO-zavisno nitrovanje ostatka tirozina
VL  - 70
IS  - 4
SP  - 601
EP  - 608
DO  - 10.2298/JSC0504601S
ER  - 

@article{
author = "Stojanović, Srđan Đ. and Stanić, Dragana and Nikolić, Milan and Raicevic, S and Spasić, Mihajlo B. and Niketic, V",
year = "2005",
abstract = "The peroxynitrite-induced nitration of manganese superoxide dismutase (MnSOD) tyrosine residue, which causes enzyme inactivation, is well established, This led to suggestions that MnSOD nitration and inactivation in vivo, detected in various diseases associated with oxidative stress and overproduction of nitric monoxide (NO), conditions which favor peroxynitrite formation, is also caused by peroxynitrite. However, our previous ill vitro study demonstrated that exposure of MnSOD to NO led to NO conversion into nitrosonium (NO+) and nitroxyl (NO-) species, which caused enzyme modifications and inactivation. Here it is reported that MnSOD is tyrosine nitrated upon exposure to NO, as well as that MnSOD nitration contributes to inactivation of the enzyme. Collectively, these observations provide a compelling argument supporting the generation of nitrating species in MnSOD exposed to NO and shed a new light on MnSOD tyrosine nitration and inactivation ill vivo. This may represent a novel mechanism by which MnSOD protects cell from deleterious effects associated with overproduction of NO. However, extensive MnSOD modification and inactivation associated with prolonged exposure to NO will amplify the toxic effects caused by increased cell superoxide and NO levels., Dobro je poznato da peroksinitrit izaziva nitrovanje ostataka tirozina u mangan-superoksid- dismutazi (MnSOD) što dovodi do inaktivacije enzima. Pokazano je da nitrovanje i inaktivacija MnSOD-a nastaje u raznim bolestima za koje je karakteristič an oksidativni stres i povećana produkcija azot-monoksida (NO). Pošto se pri ovim uslovima očekuje nastajanje peroksinitrita predloženo je da peroksinitrit izaziva nitrovanje i inaktivaciju MnSOD in vivo. U našem prethodnom radu pokazali smo da MnSOD katalizuje transformaciju NO u nitrozonijum (NO+) i nitroksil (NO–) reaktivne vrste, te identifikovali neke od modifikacija molekula enzima koje pri tome nastaju izazivajući njegovu inaktivaciju. U ovom radu je pokazano da pri izlaganju MnSOD azot-monoksidu dolazi i do nitrovanja ostatka tirozina u molekulu enzima, što doprinosi njegovoj inaktivaciji. Ovi rezultati ukazuju da pri interakciji MnSOD sa NO dolazi do nastajanja nitrujućih vrsta, što baca novo svetlo na proces nitrovanja ostataka tirozina i inaktivaciju MnSOD in vivo. Ovo može da predstavlja novi mehanizam kojim MnSOD štiti ćeliju odštetnih efekata izazvanih hiperprodukcijom azot-monoksida. Međutim ekstenzivne modifikacije i inaktivacija MnSOD do kojih dolazi pri produženom izlaganju enzima NO, uvećaće toksične efekte izazvane povećanim koncentracijama superoksida i NO u ćeliji.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Manganese superoxide dismutase (MnSOD) catalyzes NO-dependent tyrosine residue nitration, Mangan-superoksid-dismutaza (MnSOD) katalizuje NO-zavisno nitrovanje ostatka tirozina",
volume = "70",
number = "4",
pages = "601-608",
doi = "10.2298/JSC0504601S"
}

Stojanović, S. Đ., Stanić, D., Nikolić, M., Raicevic, S., Spasić, M. B.,& Niketic, V.. (2005). Manganese superoxide dismutase (MnSOD) catalyzes NO-dependent tyrosine residue nitration. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 70(4), 601-608.
https://doi.org/10.2298/JSC0504601S

Stojanović SĐ, Stanić D, Nikolić M, Raicevic S, Spasić MB, Niketic V. Manganese superoxide dismutase (MnSOD) catalyzes NO-dependent tyrosine residue nitration. in Journal of the Serbian Chemical Society. 2005;70(4):601-608.
doi:10.2298/JSC0504601S .

Stojanović, Srđan Đ., Stanić, Dragana, Nikolić, Milan, Raicevic, S, Spasić, Mihajlo B., Niketic, V, "Manganese superoxide dismutase (MnSOD) catalyzes NO-dependent tyrosine residue nitration" in Journal of the Serbian Chemical Society, 70, no. 4 (2005):601-608,
https://doi.org/10.2298/JSC0504601S . .