Popović-Đorđević, Jelena

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  • Popović-Đorđević, Jelena (11)
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Author's Bibliography

Rapid characterization of hypanthium and seed in wild and cultivated rosehip: application of Raman microscopy combined with multivariate analysis

Pećinar, Ilinka; Krstić, Đurđa D.; Caruso, Gianluca; Popović-Đorđević, Jelena

(The Royal Society, 2021)

TY  - JOUR
AU  - Pećinar, Ilinka
AU  - Krstić, Đurđa D.
AU  - Caruso, Gianluca
AU  - Popović-Đorđević, Jelena
PY  - 2021
UR  - https://royalsocietypublishing.org/doi/10.1098/rsos.202064
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4460
AB  - Rosehip (pseudo-fruit) of dog rose (Rosa canina L.) is highly valued, and owing to nutritional and sensory properties it has a significant place in the food industry. This work represents an innovative report focusing on the evaluation of the phytochemical composition of rosehips (hypanthium and seed) grown in different locations in Serbia, using Raman microspectroscopy combined with multivariate data analysis. Some significant differences arose between the analysed rosehip samples with regard to the chemical profile of both hypanthium parenchyma cells and seed, although no evident discrimination was recorded between the samples of wild and cultivated rosehip. The differences between the hypanthium samples compared were mainly determined by the content of carotenoids, phenolic compounds and polysaccharides, whereas phenolics, polysaccharides (pectin, cellulose and hemicellulose) and lipids (to a lower extent) contributed to the seed sample discrimination. The differences observed between the rosehip samples may be attributed to abiotic factors (growing, ripening and storage conditions), which had a significant impact on the carotenoid and polyphenols biosynthesis.
PB  - The Royal Society
T2  - Royal Society Open Science
T1  - Rapid characterization of hypanthium and seed in wild and cultivated rosehip: application of Raman microscopy combined with multivariate analysis
VL  - 8
IS  - 3
SP  - 202064
DO  - 10.1098/rsos.202064
ER  - 
@article{
author = "Pećinar, Ilinka and Krstić, Đurđa D. and Caruso, Gianluca and Popović-Đorđević, Jelena",
year = "2021",
abstract = "Rosehip (pseudo-fruit) of dog rose (Rosa canina L.) is highly valued, and owing to nutritional and sensory properties it has a significant place in the food industry. This work represents an innovative report focusing on the evaluation of the phytochemical composition of rosehips (hypanthium and seed) grown in different locations in Serbia, using Raman microspectroscopy combined with multivariate data analysis. Some significant differences arose between the analysed rosehip samples with regard to the chemical profile of both hypanthium parenchyma cells and seed, although no evident discrimination was recorded between the samples of wild and cultivated rosehip. The differences between the hypanthium samples compared were mainly determined by the content of carotenoids, phenolic compounds and polysaccharides, whereas phenolics, polysaccharides (pectin, cellulose and hemicellulose) and lipids (to a lower extent) contributed to the seed sample discrimination. The differences observed between the rosehip samples may be attributed to abiotic factors (growing, ripening and storage conditions), which had a significant impact on the carotenoid and polyphenols biosynthesis.",
publisher = "The Royal Society",
journal = "Royal Society Open Science",
title = "Rapid characterization of hypanthium and seed in wild and cultivated rosehip: application of Raman microscopy combined with multivariate analysis",
volume = "8",
number = "3",
pages = "202064",
doi = "10.1098/rsos.202064"
}
Pećinar, I., Krstić, Đ. D., Caruso, G.,& Popović-Đorđević, J.. (2021). Rapid characterization of hypanthium and seed in wild and cultivated rosehip: application of Raman microscopy combined with multivariate analysis. in Royal Society Open Science
The Royal Society., 8(3), 202064.
https://doi.org/10.1098/rsos.202064
Pećinar I, Krstić ĐD, Caruso G, Popović-Đorđević J. Rapid characterization of hypanthium and seed in wild and cultivated rosehip: application of Raman microscopy combined with multivariate analysis. in Royal Society Open Science. 2021;8(3):202064.
doi:10.1098/rsos.202064 .
Pećinar, Ilinka, Krstić, Đurđa D., Caruso, Gianluca, Popović-Đorđević, Jelena, "Rapid characterization of hypanthium and seed in wild and cultivated rosehip: application of Raman microscopy combined with multivariate analysis" in Royal Society Open Science, 8, no. 3 (2021):202064,
https://doi.org/10.1098/rsos.202064 . .
2
1

Supplementary data for the article: Pećinar, Ilinka, Djurdja Krstić, Gianluca Caruso, and Jelena B. Popović-Djordjević. n.d. ‘Rapid Characterization of Hypanthium and Seed in Wild and Cultivated Rosehip: Application of Raman Microscopy Combined with Multivariate Analysis’. Royal Society Open Science 8 (3): 202064. https://doi.org/10.1098/rsos.202064.

Pećinar, Ilinka; Krstić, Đurđa D.; Caruso, Gianluca; Popović-Đorđević, Jelena

(The Royal Society, 2021)

TY  - DATA
AU  - Pećinar, Ilinka
AU  - Krstić, Đurđa D.
AU  - Caruso, Gianluca
AU  - Popović-Đorđević, Jelena
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4461
PB  - The Royal Society
T2  - Royal Society Open Science
T1  - Supplementary data for the article: Pećinar, Ilinka, Djurdja Krstić, Gianluca Caruso, and Jelena B. Popović-Djordjević. n.d. ‘Rapid Characterization of Hypanthium and Seed in Wild and Cultivated Rosehip: Application of Raman Microscopy Combined with Multivariate Analysis’. Royal Society Open Science 8 (3): 202064. https://doi.org/10.1098/rsos.202064.
ER  - 
@misc{
author = "Pećinar, Ilinka and Krstić, Đurđa D. and Caruso, Gianluca and Popović-Đorđević, Jelena",
year = "2021",
publisher = "The Royal Society",
journal = "Royal Society Open Science",
title = "Supplementary data for the article: Pećinar, Ilinka, Djurdja Krstić, Gianluca Caruso, and Jelena B. Popović-Djordjević. n.d. ‘Rapid Characterization of Hypanthium and Seed in Wild and Cultivated Rosehip: Application of Raman Microscopy Combined with Multivariate Analysis’. Royal Society Open Science 8 (3): 202064. https://doi.org/10.1098/rsos.202064."
}
Pećinar, I., Krstić, Đ. D., Caruso, G.,& Popović-Đorđević, J.. (2021). Supplementary data for the article: Pećinar, Ilinka, Djurdja Krstić, Gianluca Caruso, and Jelena B. Popović-Djordjević. n.d. ‘Rapid Characterization of Hypanthium and Seed in Wild and Cultivated Rosehip: Application of Raman Microscopy Combined with Multivariate Analysis’. Royal Society Open Science 8 (3): 202064. https://doi.org/10.1098/rsos.202064.. in Royal Society Open Science
The Royal Society..
Pećinar I, Krstić ĐD, Caruso G, Popović-Đorđević J. Supplementary data for the article: Pećinar, Ilinka, Djurdja Krstić, Gianluca Caruso, and Jelena B. Popović-Djordjević. n.d. ‘Rapid Characterization of Hypanthium and Seed in Wild and Cultivated Rosehip: Application of Raman Microscopy Combined with Multivariate Analysis’. Royal Society Open Science 8 (3): 202064. https://doi.org/10.1098/rsos.202064.. in Royal Society Open Science. 2021;..
Pećinar, Ilinka, Krstić, Đurđa D., Caruso, Gianluca, Popović-Đorđević, Jelena, "Supplementary data for the article: Pećinar, Ilinka, Djurdja Krstić, Gianluca Caruso, and Jelena B. Popović-Djordjević. n.d. ‘Rapid Characterization of Hypanthium and Seed in Wild and Cultivated Rosehip: Application of Raman Microscopy Combined with Multivariate Analysis’. Royal Society Open Science 8 (3): 202064. https://doi.org/10.1098/rsos.202064." in Royal Society Open Science (2021).

Multi-elemental Analysis, Pattern Recognition Techniques of Wild and Cultivated Rosehips from Serbia, and Nutritional Aspect

Popović-Đorđević, Jelena; Paunović, Dragana M.; Milić, Aleksandra; Krstić, Đurđa D.; Siavash Moghaddam, Sina; Roje, Vibor

(2021)

TY  - JOUR
AU  - Popović-Đorđević, Jelena
AU  - Paunović, Dragana M.
AU  - Milić, Aleksandra
AU  - Krstić, Đurđa D.
AU  - Siavash Moghaddam, Sina
AU  - Roje, Vibor
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4347
AB  - Twenty-six major and trace elements, in the seed and the mesocarp of wild and cultivated rosehips from different locations in Serbia, were quantified by means of inductively coupled plasma–atomic emission spectroscopy (ICP–AES). The cultivated rosehip was investigated for the first time. In both wild and cultivated rosehips, the most abundant elements were K and Ca. Among trace elements, Mn (in both seed and mesocarp); Fe (in seeds); and B, Ba, and Sr (in mesocarp) were quantified in the highest concentrations. The higher content of Cu, K, Mn, P, and S in the seed of cultivated rosehip, as well as Ca, Mg, and Sr in the mesocarp of wild rosehip, was observed, both significant at p < 0.05. Additionally, differences between the seed and the mesocarp of studied rosehip were noticed in the content of B, Cu, Fe, K, Ni, P, S, Sr, and Ti (p < 0.05). Nutritional assessment revealed that both wild and cultivated rosehips are a valuable source of essential elements (Ca, Cu, K, Mg, Mn, and P). The absence of toxic and potentially toxic elements additionally contributes to the quality of studied Serbian rosehip. A high impact of factors such as variety, location, as well as their interaction on the content of elements in cultivated rosehip mesocarp and seed was observed. Pattern recognition techniques, principal component analysis (PCA), and hierarchical cluster analysis (HCA) were applied in order to provide insight into similarities among the analyzed samples.
T2  - Biological Trace Element Research
T1  - Multi-elemental Analysis, Pattern Recognition Techniques of Wild and Cultivated Rosehips from Serbia, and Nutritional Aspect
VL  - 199
IS  - 3
SP  - 1110
EP  - 1122
DO  - 10.1007/s12011-020-02199-4
ER  - 
@article{
author = "Popović-Đorđević, Jelena and Paunović, Dragana M. and Milić, Aleksandra and Krstić, Đurđa D. and Siavash Moghaddam, Sina and Roje, Vibor",
year = "2021",
abstract = "Twenty-six major and trace elements, in the seed and the mesocarp of wild and cultivated rosehips from different locations in Serbia, were quantified by means of inductively coupled plasma–atomic emission spectroscopy (ICP–AES). The cultivated rosehip was investigated for the first time. In both wild and cultivated rosehips, the most abundant elements were K and Ca. Among trace elements, Mn (in both seed and mesocarp); Fe (in seeds); and B, Ba, and Sr (in mesocarp) were quantified in the highest concentrations. The higher content of Cu, K, Mn, P, and S in the seed of cultivated rosehip, as well as Ca, Mg, and Sr in the mesocarp of wild rosehip, was observed, both significant at p < 0.05. Additionally, differences between the seed and the mesocarp of studied rosehip were noticed in the content of B, Cu, Fe, K, Ni, P, S, Sr, and Ti (p < 0.05). Nutritional assessment revealed that both wild and cultivated rosehips are a valuable source of essential elements (Ca, Cu, K, Mg, Mn, and P). The absence of toxic and potentially toxic elements additionally contributes to the quality of studied Serbian rosehip. A high impact of factors such as variety, location, as well as their interaction on the content of elements in cultivated rosehip mesocarp and seed was observed. Pattern recognition techniques, principal component analysis (PCA), and hierarchical cluster analysis (HCA) were applied in order to provide insight into similarities among the analyzed samples.",
journal = "Biological Trace Element Research",
title = "Multi-elemental Analysis, Pattern Recognition Techniques of Wild and Cultivated Rosehips from Serbia, and Nutritional Aspect",
volume = "199",
number = "3",
pages = "1110-1122",
doi = "10.1007/s12011-020-02199-4"
}
Popović-Đorđević, J., Paunović, D. M., Milić, A., Krstić, Đ. D., Siavash Moghaddam, S.,& Roje, V.. (2021). Multi-elemental Analysis, Pattern Recognition Techniques of Wild and Cultivated Rosehips from Serbia, and Nutritional Aspect. in Biological Trace Element Research, 199(3), 1110-1122.
https://doi.org/10.1007/s12011-020-02199-4
Popović-Đorđević J, Paunović DM, Milić A, Krstić ĐD, Siavash Moghaddam S, Roje V. Multi-elemental Analysis, Pattern Recognition Techniques of Wild and Cultivated Rosehips from Serbia, and Nutritional Aspect. in Biological Trace Element Research. 2021;199(3):1110-1122.
doi:10.1007/s12011-020-02199-4 .
Popović-Đorđević, Jelena, Paunović, Dragana M., Milić, Aleksandra, Krstić, Đurđa D., Siavash Moghaddam, Sina, Roje, Vibor, "Multi-elemental Analysis, Pattern Recognition Techniques of Wild and Cultivated Rosehips from Serbia, and Nutritional Aspect" in Biological Trace Element Research, 199, no. 3 (2021):1110-1122,
https://doi.org/10.1007/s12011-020-02199-4 . .
4
3
3

Quantification of Selected Toxic and Potentially Toxic Elements in Vegetables, and Health Risk Assessment

Miljković, Irena; Popović-Đorđević, Jelena; Rajković, Miloš B.; Kostić, Aleksandar Ž.; Popović, Blaženka; Brčeski, Ilija; Brka, Muhamed; Omanović-Mikličanin, Enisa; Karić, Lutvija; Falan, Vedad; Toroman, Almir

(Springer International Publishing, 2020)

TY  - CONF
AU  - Miljković, Irena
AU  - Popović-Đorđević, Jelena
AU  - Rajković, Miloš B.
AU  - Kostić, Aleksandar Ž.
AU  - Popović, Blaženka
AU  - Brčeski, Ilija
AU  - Brka, Muhamed
AU  - Omanović-Mikličanin, Enisa
AU  - Karić, Lutvija
AU  - Falan, Vedad
AU  - Toroman, Almir
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4278
AB  - Vegetables play an important role in human nutrition and their importance in diet is determined by its chemical composition. Numerous studies indicate a high degree of contamination of soil and plants produced in certain agro-ecological conditions, especially near urban and industrial areas. Accordingly, toxic and potentially toxic elements (aluminum, chromium, copper, manganese, nickel, lead and zinc) were quantified in edible parts of four vegetable species (potato, cabbage, carrot and broccoli) by means of inductively coupled plasma–optical emission spectrometry (ICP–OES). In addition, health risk assessment was done and expressed through estimated weekly intake of elements (EWI) and hazard quotient (HQ). Samples of each species originating from different localities were collected from three green markets in the city of Belgrade (Serbia). The content of studied elements ranged from 1.32 to 4.00, 0.31 to 5.77, 3.50 to 23.11, 1.82 to 11.17 and 2.11 to 10.62 mg/kg for aluminum, cooper, manganese, nickel and zinc, respectively. Chromium was detected in carrot sample (1.76 mg/kg), whereas concentration of lead in two samples of broccoli exceeded the maximum allowed concentration (>0.3 mg/kg) set by the national regulations. The average estimated weekly intakes for Al, Cu, and Zn were within the safe limits set by FAO/WHO, while for Ni and Pb in some vegetables were considerably higher than proposed values. In respect to the obtained results, a great weekly health risk was indicated for chromium, nickel and lead with the highest HQ values: 2.44, 10.32 and 2.02, respectively. The results of the study impose the necessity for continuous monitoring of harmful elements content in individual vegetable crops as well as strict regulative guide-lines in order to diminish possibility of contamination.
PB  - Springer International Publishing
C3  - 30th Scientific-Experts Conference of Agriculture and Food Industry
T1  - Quantification of Selected Toxic and Potentially Toxic Elements in Vegetables, and Health Risk Assessment
SP  - 229
EP  - 236
DO  - 10.1007/978-3-030-40049-1_29
ER  - 
@conference{
author = "Miljković, Irena and Popović-Đorđević, Jelena and Rajković, Miloš B. and Kostić, Aleksandar Ž. and Popović, Blaženka and Brčeski, Ilija and Brka, Muhamed and Omanović-Mikličanin, Enisa and Karić, Lutvija and Falan, Vedad and Toroman, Almir",
year = "2020",
abstract = "Vegetables play an important role in human nutrition and their importance in diet is determined by its chemical composition. Numerous studies indicate a high degree of contamination of soil and plants produced in certain agro-ecological conditions, especially near urban and industrial areas. Accordingly, toxic and potentially toxic elements (aluminum, chromium, copper, manganese, nickel, lead and zinc) were quantified in edible parts of four vegetable species (potato, cabbage, carrot and broccoli) by means of inductively coupled plasma–optical emission spectrometry (ICP–OES). In addition, health risk assessment was done and expressed through estimated weekly intake of elements (EWI) and hazard quotient (HQ). Samples of each species originating from different localities were collected from three green markets in the city of Belgrade (Serbia). The content of studied elements ranged from 1.32 to 4.00, 0.31 to 5.77, 3.50 to 23.11, 1.82 to 11.17 and 2.11 to 10.62 mg/kg for aluminum, cooper, manganese, nickel and zinc, respectively. Chromium was detected in carrot sample (1.76 mg/kg), whereas concentration of lead in two samples of broccoli exceeded the maximum allowed concentration (>0.3 mg/kg) set by the national regulations. The average estimated weekly intakes for Al, Cu, and Zn were within the safe limits set by FAO/WHO, while for Ni and Pb in some vegetables were considerably higher than proposed values. In respect to the obtained results, a great weekly health risk was indicated for chromium, nickel and lead with the highest HQ values: 2.44, 10.32 and 2.02, respectively. The results of the study impose the necessity for continuous monitoring of harmful elements content in individual vegetable crops as well as strict regulative guide-lines in order to diminish possibility of contamination.",
publisher = "Springer International Publishing",
journal = "30th Scientific-Experts Conference of Agriculture and Food Industry",
title = "Quantification of Selected Toxic and Potentially Toxic Elements in Vegetables, and Health Risk Assessment",
pages = "229-236",
doi = "10.1007/978-3-030-40049-1_29"
}
Miljković, I., Popović-Đorđević, J., Rajković, M. B., Kostić, A. Ž., Popović, B., Brčeski, I., Brka, M., Omanović-Mikličanin, E., Karić, L., Falan, V.,& Toroman, A.. (2020). Quantification of Selected Toxic and Potentially Toxic Elements in Vegetables, and Health Risk Assessment. in 30th Scientific-Experts Conference of Agriculture and Food Industry
Springer International Publishing., 229-236.
https://doi.org/10.1007/978-3-030-40049-1_29
Miljković I, Popović-Đorđević J, Rajković MB, Kostić AŽ, Popović B, Brčeski I, Brka M, Omanović-Mikličanin E, Karić L, Falan V, Toroman A. Quantification of Selected Toxic and Potentially Toxic Elements in Vegetables, and Health Risk Assessment. in 30th Scientific-Experts Conference of Agriculture and Food Industry. 2020;:229-236.
doi:10.1007/978-3-030-40049-1_29 .
Miljković, Irena, Popović-Đorđević, Jelena, Rajković, Miloš B., Kostić, Aleksandar Ž., Popović, Blaženka, Brčeski, Ilija, Brka, Muhamed, Omanović-Mikličanin, Enisa, Karić, Lutvija, Falan, Vedad, Toroman, Almir, "Quantification of Selected Toxic and Potentially Toxic Elements in Vegetables, and Health Risk Assessment" in 30th Scientific-Experts Conference of Agriculture and Food Industry (2020):229-236,
https://doi.org/10.1007/978-3-030-40049-1_29 . .
1
1

Essential Elements as a Distinguishing Factor between Mycorrhizal Potentials of Two Cohabiting Truffle Species in Riparian Forest Habitat in Serbia

Popović-Đorđević, Jelena; Marjanović, Žaklina S.; Gršić, Nemanja; Adžić, Tamara; Popović, Blazenka S.; Bogosavljević, Jelena; Brčeski, Ilija

(Wiley-VHCA AG, 2019)

TY  - JOUR
AU  - Popović-Đorđević, Jelena
AU  - Marjanović, Žaklina S.
AU  - Gršić, Nemanja
AU  - Adžić, Tamara
AU  - Popović, Blazenka S.
AU  - Bogosavljević, Jelena
AU  - Brčeski, Ilija
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2921
AB  - True truffles (Tuber sp.) that establish ectomycorrhizal symbiosis (ECM) with trees in the Mediterranean and temporal regions have species specific abilities to assimilate soil born elements. Suitable habitats are usually inhabited by few truffle species, while distinguishing their symbiotic potentials appeared very difficult. Two species that commonly inhabit riparian forests in Serbia are the most prized one, Tuber magnatum Pico (Piedmont white truffle) and not so highly valued Tuber brumale Vitt. In order to assess potential differences between their assimilation and accumulation abilities, the differences between contents of elements that may be the subjects of the symbiotic trade between the host plant and fungi were evaluated in accumulation target (ascocarps) and their source (the soil). Essential (K, Na, Ca, Mg, Fe, P, S, and Zn) and essential trace elements (Co, Cr, Cu, Mn, and Se) in truffles and soil samples were determined by means of inductively coupled plasma with optical emission spectrometry (ICP-OES). Their concentrations (mg/kg) in ascocarps were in the range from 1.364±0.591 (Cr) to 10760.862±16.058 (K), while in soil ranged from 23.035±0.010 (Cr) to 20809.300±122.934 (Fe). Element accumulation potential (bioaccumulation factor) was calculated in the system truffle/soil. The statistical approaches were used for establishing the differences, while the possible differentiation between symbiotic potentials of two mycelia in the defined soil conditions was discussed.
PB  - Wiley-VHCA AG
T2  - Chemistry and Biodiversity
T1  - Essential Elements as a Distinguishing Factor between Mycorrhizal Potentials of Two Cohabiting Truffle Species in Riparian Forest Habitat in Serbia
VL  - 16
IS  - 4
SP  - 1800693
DO  - 10.1002/cbdv.201800693
ER  - 
@article{
author = "Popović-Đorđević, Jelena and Marjanović, Žaklina S. and Gršić, Nemanja and Adžić, Tamara and Popović, Blazenka S. and Bogosavljević, Jelena and Brčeski, Ilija",
year = "2019",
abstract = "True truffles (Tuber sp.) that establish ectomycorrhizal symbiosis (ECM) with trees in the Mediterranean and temporal regions have species specific abilities to assimilate soil born elements. Suitable habitats are usually inhabited by few truffle species, while distinguishing their symbiotic potentials appeared very difficult. Two species that commonly inhabit riparian forests in Serbia are the most prized one, Tuber magnatum Pico (Piedmont white truffle) and not so highly valued Tuber brumale Vitt. In order to assess potential differences between their assimilation and accumulation abilities, the differences between contents of elements that may be the subjects of the symbiotic trade between the host plant and fungi were evaluated in accumulation target (ascocarps) and their source (the soil). Essential (K, Na, Ca, Mg, Fe, P, S, and Zn) and essential trace elements (Co, Cr, Cu, Mn, and Se) in truffles and soil samples were determined by means of inductively coupled plasma with optical emission spectrometry (ICP-OES). Their concentrations (mg/kg) in ascocarps were in the range from 1.364±0.591 (Cr) to 10760.862±16.058 (K), while in soil ranged from 23.035±0.010 (Cr) to 20809.300±122.934 (Fe). Element accumulation potential (bioaccumulation factor) was calculated in the system truffle/soil. The statistical approaches were used for establishing the differences, while the possible differentiation between symbiotic potentials of two mycelia in the defined soil conditions was discussed.",
publisher = "Wiley-VHCA AG",
journal = "Chemistry and Biodiversity",
title = "Essential Elements as a Distinguishing Factor between Mycorrhizal Potentials of Two Cohabiting Truffle Species in Riparian Forest Habitat in Serbia",
volume = "16",
number = "4",
pages = "1800693",
doi = "10.1002/cbdv.201800693"
}
Popović-Đorđević, J., Marjanović, Ž. S., Gršić, N., Adžić, T., Popović, B. S., Bogosavljević, J.,& Brčeski, I.. (2019). Essential Elements as a Distinguishing Factor between Mycorrhizal Potentials of Two Cohabiting Truffle Species in Riparian Forest Habitat in Serbia. in Chemistry and Biodiversity
Wiley-VHCA AG., 16(4), 1800693.
https://doi.org/10.1002/cbdv.201800693
Popović-Đorđević J, Marjanović ŽS, Gršić N, Adžić T, Popović BS, Bogosavljević J, Brčeski I. Essential Elements as a Distinguishing Factor between Mycorrhizal Potentials of Two Cohabiting Truffle Species in Riparian Forest Habitat in Serbia. in Chemistry and Biodiversity. 2019;16(4):1800693.
doi:10.1002/cbdv.201800693 .
Popović-Đorđević, Jelena, Marjanović, Žaklina S., Gršić, Nemanja, Adžić, Tamara, Popović, Blazenka S., Bogosavljević, Jelena, Brčeski, Ilija, "Essential Elements as a Distinguishing Factor between Mycorrhizal Potentials of Two Cohabiting Truffle Species in Riparian Forest Habitat in Serbia" in Chemistry and Biodiversity, 16, no. 4 (2019):1800693,
https://doi.org/10.1002/cbdv.201800693 . .
1
6
6
7

Content and Weekly Intake of Essential and Toxic Elements in Serbian Vegetables

Popović-Đorđević, Jelena; Bokan, N.; Dramićanin, Aleksandra M.; Brčeski, Ilija; Kostić, Aleksandar Ž.

(Scibulcom Ltd, Sofia, 2017)

TY  - JOUR
AU  - Popović-Đorđević, Jelena
AU  - Bokan, N.
AU  - Dramićanin, Aleksandra M.
AU  - Brčeski, Ilija
AU  - Kostić, Aleksandar Ž.
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2559
AB  - Food quality and safety are a major concern of the modern world. The contents of twelve elements were determined in selected vegetable species taken at the city green market using ICP-OES analysis. To assess the safety of dietary intake of these metals through the consumption of vegetables, the estimated weekly intake (EWI) was calculated and compared with the provisional tolerable weekly intake (PTWI). The most abundant element was Al, whereas As, Cd, Co, Sb and Mo were not found in studied vegetables. Lead exceeded the maximum allowed concentration (MAC) set by national regulations. The average estimated weekly intake for aluminum, chromium, copper, manganese, nickel, lead, and zinc were 0.392, 0.010, 0.015, 0.096, 0.019, 0.038 and 0.124 mg kg(-1), respectively. Cr, Ni and Pb in some vegetables were considerably higher than the safe limits set by FAO/WHO.
PB  - Scibulcom Ltd, Sofia
T2  - Journal of Environmental Protection and Ecology
T1  - Content and Weekly Intake of Essential and Toxic Elements in Serbian Vegetables
VL  - 18
IS  - 3
SP  - 889
EP  - 898
UR  - Kon_3375
ER  - 
@article{
author = "Popović-Đorđević, Jelena and Bokan, N. and Dramićanin, Aleksandra M. and Brčeski, Ilija and Kostić, Aleksandar Ž.",
year = "2017",
abstract = "Food quality and safety are a major concern of the modern world. The contents of twelve elements were determined in selected vegetable species taken at the city green market using ICP-OES analysis. To assess the safety of dietary intake of these metals through the consumption of vegetables, the estimated weekly intake (EWI) was calculated and compared with the provisional tolerable weekly intake (PTWI). The most abundant element was Al, whereas As, Cd, Co, Sb and Mo were not found in studied vegetables. Lead exceeded the maximum allowed concentration (MAC) set by national regulations. The average estimated weekly intake for aluminum, chromium, copper, manganese, nickel, lead, and zinc were 0.392, 0.010, 0.015, 0.096, 0.019, 0.038 and 0.124 mg kg(-1), respectively. Cr, Ni and Pb in some vegetables were considerably higher than the safe limits set by FAO/WHO.",
publisher = "Scibulcom Ltd, Sofia",
journal = "Journal of Environmental Protection and Ecology",
title = "Content and Weekly Intake of Essential and Toxic Elements in Serbian Vegetables",
volume = "18",
number = "3",
pages = "889-898",
url = "Kon_3375"
}
Popović-Đorđević, J., Bokan, N., Dramićanin, A. M., Brčeski, I.,& Kostić, A. Ž.. (2017). Content and Weekly Intake of Essential and Toxic Elements in Serbian Vegetables. in Journal of Environmental Protection and Ecology
Scibulcom Ltd, Sofia., 18(3), 889-898.
Kon_3375
Popović-Đorđević J, Bokan N, Dramićanin AM, Brčeski I, Kostić AŽ. Content and Weekly Intake of Essential and Toxic Elements in Serbian Vegetables. in Journal of Environmental Protection and Ecology. 2017;18(3):889-898.
Kon_3375 .
Popović-Đorđević, Jelena, Bokan, N., Dramićanin, Aleksandra M., Brčeski, Ilija, Kostić, Aleksandar Ž., "Content and Weekly Intake of Essential and Toxic Elements in Serbian Vegetables" in Journal of Environmental Protection and Ecology, 18, no. 3 (2017):889-898,
Kon_3375 .
5
6

The polyphenolics and carbohydrates as indicators of botanical and geographical origin of Serbian autochthonous clones of red spice paprika

Mudrić, Sanja Ž.; Gašić, Uroš M.; Dramićanin, Aleksandra M.; Ćirić, Ivanka; Milojković-Opsenica, Dušanka; Popović-Đorđević, Jelena; Momirović, Nebojša M.; Tešić, Živoslav Lj.

(Elsevier Sci Ltd, Oxford, 2017)

TY  - JOUR
AU  - Mudrić, Sanja Ž.
AU  - Gašić, Uroš M.
AU  - Dramićanin, Aleksandra M.
AU  - Ćirić, Ivanka
AU  - Milojković-Opsenica, Dušanka
AU  - Popović-Đorđević, Jelena
AU  - Momirović, Nebojša M.
AU  - Tešić, Živoslav Lj.
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/1946
AB  - Spice peppers (Capsicum annuum L.) var. Lemeska and Lakosnicka paprika were investigated to evaluate their polyphenolic and carbohydrate profiles and antioxidant activity. A total of forty-nine polyphenolics were identified using ultrahigh-performance liquid chromatography (UHPLC) coupled to LTQ OrbiTrap mass analyzer. Twenty-five of them were quantified using available standards, while the other compounds were confirmed by exact mass search of their deprotonated molecule [M-H](-) and its MS4 fragmentation. Thirteen carbohydrates were quantified using high-performance anion exchange chromatography (HPAEC) with pulsed amperometric detection (PAD). Radical scavenging activity (RSA) ranged from 17.32 to 48.34 mmol TE (Trolox equivalent)/kg DW (dry weight) and total phenolics content (TPC) was ranged between 7.03 and 14.92 g GAE (gallic acid equivalents)/kg DW. To our best knowledge, five polyphenolic compounds were for the first time tentatively identified in paprika: 5-O-p-coumaroylquinic acid, luteolin 7-O-(2 ''-O-pentosyl-4 ''-O-hexosyl)hexoside, quercetin 3-O-(2 ''-O-hexosyl)rhamnoside, isorhamnetin 3-O-[6 ''-O-(5-hydroxyferuloyl)hexoside]-7-O-rhamnoside, and luteolin 7-O-[2 ''-O-(5'''-O-sinapoyl)pentosyl-6 ''-O-malonyl]hexoside. (C) 2016 Elsevier Ltd. All rights reserved.
PB  - Elsevier Sci Ltd, Oxford
T2  - Food Chemistry
T1  - The polyphenolics and carbohydrates as indicators of botanical and geographical origin of Serbian autochthonous clones of red spice paprika
VL  - 217
SP  - 705
EP  - 715
DO  - 10.1016/j.foodchem.2016.09.038
UR  - Kon_3065
ER  - 
@article{
author = "Mudrić, Sanja Ž. and Gašić, Uroš M. and Dramićanin, Aleksandra M. and Ćirić, Ivanka and Milojković-Opsenica, Dušanka and Popović-Đorđević, Jelena and Momirović, Nebojša M. and Tešić, Živoslav Lj.",
year = "2017",
abstract = "Spice peppers (Capsicum annuum L.) var. Lemeska and Lakosnicka paprika were investigated to evaluate their polyphenolic and carbohydrate profiles and antioxidant activity. A total of forty-nine polyphenolics were identified using ultrahigh-performance liquid chromatography (UHPLC) coupled to LTQ OrbiTrap mass analyzer. Twenty-five of them were quantified using available standards, while the other compounds were confirmed by exact mass search of their deprotonated molecule [M-H](-) and its MS4 fragmentation. Thirteen carbohydrates were quantified using high-performance anion exchange chromatography (HPAEC) with pulsed amperometric detection (PAD). Radical scavenging activity (RSA) ranged from 17.32 to 48.34 mmol TE (Trolox equivalent)/kg DW (dry weight) and total phenolics content (TPC) was ranged between 7.03 and 14.92 g GAE (gallic acid equivalents)/kg DW. To our best knowledge, five polyphenolic compounds were for the first time tentatively identified in paprika: 5-O-p-coumaroylquinic acid, luteolin 7-O-(2 ''-O-pentosyl-4 ''-O-hexosyl)hexoside, quercetin 3-O-(2 ''-O-hexosyl)rhamnoside, isorhamnetin 3-O-[6 ''-O-(5-hydroxyferuloyl)hexoside]-7-O-rhamnoside, and luteolin 7-O-[2 ''-O-(5'''-O-sinapoyl)pentosyl-6 ''-O-malonyl]hexoside. (C) 2016 Elsevier Ltd. All rights reserved.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Food Chemistry",
title = "The polyphenolics and carbohydrates as indicators of botanical and geographical origin of Serbian autochthonous clones of red spice paprika",
volume = "217",
pages = "705-715",
doi = "10.1016/j.foodchem.2016.09.038",
url = "Kon_3065"
}
Mudrić, S. Ž., Gašić, U. M., Dramićanin, A. M., Ćirić, I., Milojković-Opsenica, D., Popović-Đorđević, J., Momirović, N. M.,& Tešić, Ž. Lj.. (2017). The polyphenolics and carbohydrates as indicators of botanical and geographical origin of Serbian autochthonous clones of red spice paprika. in Food Chemistry
Elsevier Sci Ltd, Oxford., 217, 705-715.
https://doi.org/10.1016/j.foodchem.2016.09.038
Kon_3065
Mudrić SŽ, Gašić UM, Dramićanin AM, Ćirić I, Milojković-Opsenica D, Popović-Đorđević J, Momirović NM, Tešić ŽL. The polyphenolics and carbohydrates as indicators of botanical and geographical origin of Serbian autochthonous clones of red spice paprika. in Food Chemistry. 2017;217:705-715.
doi:10.1016/j.foodchem.2016.09.038
Kon_3065 .
Mudrić, Sanja Ž., Gašić, Uroš M., Dramićanin, Aleksandra M., Ćirić, Ivanka, Milojković-Opsenica, Dušanka, Popović-Đorđević, Jelena, Momirović, Nebojša M., Tešić, Živoslav Lj., "The polyphenolics and carbohydrates as indicators of botanical and geographical origin of Serbian autochthonous clones of red spice paprika" in Food Chemistry, 217 (2017):705-715,
https://doi.org/10.1016/j.foodchem.2016.09.038 .,
Kon_3065 .
41
36
38

Evaluation of the Quality of Drinking Water in Rasina District, Serbia: Physicochemical and Bacteriological Viewpoint

Pantelić, Nebojša Đ.; Dramićanin, Aleksandra M.; Milovanović, Danijela B.; Popović-Đorđević, Jelena; Kostić, Aleksandar Ž.

(Editura Acad Romane, Bucuresti, 2017)

TY  - JOUR
AU  - Pantelić, Nebojša Đ.
AU  - Dramićanin, Aleksandra M.
AU  - Milovanović, Danijela B.
AU  - Popović-Đorđević, Jelena
AU  - Kostić, Aleksandar Ž.
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2070
AB  - The water samples from Rasina District (Serbia) were evaluated for principal physical and chemical parameters, as well as for microbiological contaminants. Results were compared to National and World Health Organization (WHO) water quality standards. Several samples contained total organic matter, ammonia, residual chlorine, nitrite, nitrate, iron and manganese above proposed legislation limits. For samples contaminated with faecal bacteria, Streptococcus faecalis, aerobic mesophilic bacteria, coliform bacteria and sulfite-reducing clostridia special attention should be payed to drinking water disinfecting methods. The potential health risks of waterborne diseases due to consumption of water from contaminated sources could be implied.
PB  - Editura Acad Romane, Bucuresti
T2  - Romanian Journal of Physics
T1  - Evaluation of the Quality of Drinking Water in Rasina District, Serbia: Physicochemical and Bacteriological Viewpoint
VL  - 62
IS  - 9-10
ER  - 
@article{
author = "Pantelić, Nebojša Đ. and Dramićanin, Aleksandra M. and Milovanović, Danijela B. and Popović-Đorđević, Jelena and Kostić, Aleksandar Ž.",
year = "2017",
abstract = "The water samples from Rasina District (Serbia) were evaluated for principal physical and chemical parameters, as well as for microbiological contaminants. Results were compared to National and World Health Organization (WHO) water quality standards. Several samples contained total organic matter, ammonia, residual chlorine, nitrite, nitrate, iron and manganese above proposed legislation limits. For samples contaminated with faecal bacteria, Streptococcus faecalis, aerobic mesophilic bacteria, coliform bacteria and sulfite-reducing clostridia special attention should be payed to drinking water disinfecting methods. The potential health risks of waterborne diseases due to consumption of water from contaminated sources could be implied.",
publisher = "Editura Acad Romane, Bucuresti",
journal = "Romanian Journal of Physics",
title = "Evaluation of the Quality of Drinking Water in Rasina District, Serbia: Physicochemical and Bacteriological Viewpoint",
volume = "62",
number = "9-10"
}
Pantelić, N. Đ., Dramićanin, A. M., Milovanović, D. B., Popović-Đorđević, J.,& Kostić, A. Ž.. (2017). Evaluation of the Quality of Drinking Water in Rasina District, Serbia: Physicochemical and Bacteriological Viewpoint. in Romanian Journal of Physics
Editura Acad Romane, Bucuresti., 62(9-10).
Pantelić NĐ, Dramićanin AM, Milovanović DB, Popović-Đorđević J, Kostić AŽ. Evaluation of the Quality of Drinking Water in Rasina District, Serbia: Physicochemical and Bacteriological Viewpoint. in Romanian Journal of Physics. 2017;62(9-10)..
Pantelić, Nebojša Đ., Dramićanin, Aleksandra M., Milovanović, Danijela B., Popović-Đorđević, Jelena, Kostić, Aleksandar Ž., "Evaluation of the Quality of Drinking Water in Rasina District, Serbia: Physicochemical and Bacteriological Viewpoint" in Romanian Journal of Physics, 62, no. 9-10 (2017).
2
3

Supplementary data for article: Mudric, S. Z.; Gašić, U. M.; Dramićanin, A. M.; Ćirić, I.; Milojković-Opsenica, D.; Popović-Đorđević, J. B.; Momirović, N. M.; Tešić, Ž. L. The Polyphenolics and Carbohydrates as Indicators of Botanical and Geographical Origin of Serbian Autochthonous Clones of Red Spice Paprika. Food Chemistry 2017, 217, 705–715. https://doi.org/10.1016/j.foodchem.2016.09.038

Mudrić, Sanja Ž.; Gašić, Uroš M.; Dramićanin, Aleksandra M.; Ćirić, Ivanka; Milojković-Opsenica, Dušanka; Popović-Đorđević, Jelena; Momirović, Nebojša M.; Tešić, Živoslav Lj.

(Elsevier Sci Ltd, Oxford, 2017)

TY  - DATA
AU  - Mudrić, Sanja Ž.
AU  - Gašić, Uroš M.
AU  - Dramićanin, Aleksandra M.
AU  - Ćirić, Ivanka
AU  - Milojković-Opsenica, Dušanka
AU  - Popović-Đorđević, Jelena
AU  - Momirović, Nebojša M.
AU  - Tešić, Živoslav Lj.
PY  - 2017
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3009
PB  - Elsevier Sci Ltd, Oxford
T2  - Food Chemistry
T1  - Supplementary data for article: Mudric, S. Z.; Gašić, U. M.; Dramićanin, A. M.; Ćirić, I.; Milojković-Opsenica, D.; Popović-Đorđević, J. B.; Momirović, N. M.; Tešić, Ž. L. The Polyphenolics and Carbohydrates as Indicators of Botanical and Geographical Origin of Serbian Autochthonous Clones of Red Spice Paprika. Food Chemistry 2017, 217, 705–715. https://doi.org/10.1016/j.foodchem.2016.09.038
ER  - 
@misc{
author = "Mudrić, Sanja Ž. and Gašić, Uroš M. and Dramićanin, Aleksandra M. and Ćirić, Ivanka and Milojković-Opsenica, Dušanka and Popović-Đorđević, Jelena and Momirović, Nebojša M. and Tešić, Živoslav Lj.",
year = "2017, 2017",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Food Chemistry",
title = "Supplementary data for article: Mudric, S. Z.; Gašić, U. M.; Dramićanin, A. M.; Ćirić, I.; Milojković-Opsenica, D.; Popović-Đorđević, J. B.; Momirović, N. M.; Tešić, Ž. L. The Polyphenolics and Carbohydrates as Indicators of Botanical and Geographical Origin of Serbian Autochthonous Clones of Red Spice Paprika. Food Chemistry 2017, 217, 705–715. https://doi.org/10.1016/j.foodchem.2016.09.038"
}
Mudrić, S. Ž., Gašić, U. M., Dramićanin, A. M., Ćirić, I., Milojković-Opsenica, D., Popović-Đorđević, J., Momirović, N. M.,& Tešić, Ž. Lj.. (2017). Supplementary data for article: Mudric, S. Z.; Gašić, U. M.; Dramićanin, A. M.; Ćirić, I.; Milojković-Opsenica, D.; Popović-Đorđević, J. B.; Momirović, N. M.; Tešić, Ž. L. The Polyphenolics and Carbohydrates as Indicators of Botanical and Geographical Origin of Serbian Autochthonous Clones of Red Spice Paprika. Food Chemistry 2017, 217, 705–715. https://doi.org/10.1016/j.foodchem.2016.09.038. in Food Chemistry
Elsevier Sci Ltd, Oxford..
Mudrić SŽ, Gašić UM, Dramićanin AM, Ćirić I, Milojković-Opsenica D, Popović-Đorđević J, Momirović NM, Tešić ŽL. Supplementary data for article: Mudric, S. Z.; Gašić, U. M.; Dramićanin, A. M.; Ćirić, I.; Milojković-Opsenica, D.; Popović-Đorđević, J. B.; Momirović, N. M.; Tešić, Ž. L. The Polyphenolics and Carbohydrates as Indicators of Botanical and Geographical Origin of Serbian Autochthonous Clones of Red Spice Paprika. Food Chemistry 2017, 217, 705–715. https://doi.org/10.1016/j.foodchem.2016.09.038. in Food Chemistry. 2017;..
Mudrić, Sanja Ž., Gašić, Uroš M., Dramićanin, Aleksandra M., Ćirić, Ivanka, Milojković-Opsenica, Dušanka, Popović-Đorđević, Jelena, Momirović, Nebojša M., Tešić, Živoslav Lj., "Supplementary data for article: Mudric, S. Z.; Gašić, U. M.; Dramićanin, A. M.; Ćirić, I.; Milojković-Opsenica, D.; Popović-Đorđević, J. B.; Momirović, N. M.; Tešić, Ž. L. The Polyphenolics and Carbohydrates as Indicators of Botanical and Geographical Origin of Serbian Autochthonous Clones of Red Spice Paprika. Food Chemistry 2017, 217, 705–715. https://doi.org/10.1016/j.foodchem.2016.09.038" in Food Chemistry (2017).

Glutarimides: Biological Activity, General Synthetic Methods and Physicochemical Properties

Popović-Đorđević, Jelena; Vitnik, Vesna D.; Vitnik, Zeljko J.; Ivanović, Milovan

(Assoc Chemical Engineers Serbia, Belgrade, 2015)

TY  - JOUR
AU  - Popović-Đorđević, Jelena
AU  - Vitnik, Vesna D.
AU  - Vitnik, Zeljko J.
AU  - Ivanović, Milovan
PY  - 2015
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2015
AB  - Glutarimides, 2,6-dioxopiperidines, are compounds that rarely occur in natural sources, but so far isolated ones exert widespread pharmacological activities, which makes them valuable as potential pharmacotherapeutics. Glutarimides act as androgen receptor antagonists, anti-inflammatory, anxiolytics, antibacterials, and tumor suppressing agents. Some synthetic glutarimide derivatives are already in use as immunosuppressive and sedative (e.g., thalidomide) or anxiolytics (buspirone) drugs. The wide applicability of this class of compounds, justify the interest of scientists to explore new pathways for its syntheses. General methods for synthesis of six-membered imide ring are presented in this paper. These methods include: a) reaction of dicarboxylic acids with ammonia or primary amine, b) reactions of cyclization: amido-acids, diamides, dinitriles, nitrilo-acids, amidonitriles, amido-esters, amidoacyl-chlorides or diacyl-chlorides, c) addition of carbon-monoxide on alpha,beta-unsaturated amides, d) oxidation reactions, e) Michael addition of active methylen compounds on methacrylamide or conjugated amides. Some of the described methods are used for closing glutarimide ring in syntheses of pharmacological active compounds sesbanimide and aldose reductase inhibitors (ARI). Analyses of the geometry, as well as, the spectroscopic analyses (NMR and FT-IR) of some glutarimides are presented due to their broad spectrum of pharmacological activity. To elucidate structures of glutarimides, geometrical parameters of newly synthesized tert-pentyl-1-benzyl-4-methyl-glutarimide-3-carboxylate (PBMG) are analyzed and compared with the experimental data from X-ray analysis for glutarimide. Moreover, molecular electrostatic potential (MEP) surface which is plotted over the optimized geometry to elucidate the reactivity of PBMG molecule is analyzed. The electronic properties of glutarimide derivatives are explained on the example of thalidomide. The Frontier Molecular Orbital (FMO) and their energies are presented, as well as the energy gap between them.
AB  - U ovom radu dat je prikaz metoda za sintezu šestočlanih cikličnih imida. Glutarimidi, 2,6-dioksopiperidini, su značajna biološka jedinjenja i deluju kao antagonisti adrenogenih receptora, antiinflamatorni agensi, anksiolitici, antivirotici, antibiotici i agensi koji sprečavaju rast pojedinih vrsta tumora. Prikazana je i njihova spektralna analiza (FT-IR i NMR), zbog potvrde stukture, kao i analiza graničnih molekulskih orbitala koja daje prikaz elektronskih svojstava ovih molekula, što je važno zbog njihove biološke aktivnosti. Da bi se predstavila hemijska reaktivnost glutarimida predstavljen je molekulski elektronski potencijal (MEP) iz prethodno optimizovane geometrije reprezentativnog primera terc-pentil-1- -benzil-4-metil-glutarimid-3-karboksilata (skraćenica PBMG). Elektronska svojstva su objašnjena na primeru talidomida.
PB  - Assoc Chemical Engineers Serbia, Belgrade
T2  - Hemijska industrija
T1  - Glutarimides: Biological Activity, General Synthetic Methods and Physicochemical Properties
T1  - Glutarimidi - biološka aktivnost, opšti postupci za sintezu i fizičko-hemijske karakteristike
VL  - 69
IS  - 5
SP  - 523
EP  - 536
DO  - 10.2298/HEMIND140701073P
UR  - Kon_2970
ER  - 
@article{
author = "Popović-Đorđević, Jelena and Vitnik, Vesna D. and Vitnik, Zeljko J. and Ivanović, Milovan",
year = "2015",
abstract = "Glutarimides, 2,6-dioxopiperidines, are compounds that rarely occur in natural sources, but so far isolated ones exert widespread pharmacological activities, which makes them valuable as potential pharmacotherapeutics. Glutarimides act as androgen receptor antagonists, anti-inflammatory, anxiolytics, antibacterials, and tumor suppressing agents. Some synthetic glutarimide derivatives are already in use as immunosuppressive and sedative (e.g., thalidomide) or anxiolytics (buspirone) drugs. The wide applicability of this class of compounds, justify the interest of scientists to explore new pathways for its syntheses. General methods for synthesis of six-membered imide ring are presented in this paper. These methods include: a) reaction of dicarboxylic acids with ammonia or primary amine, b) reactions of cyclization: amido-acids, diamides, dinitriles, nitrilo-acids, amidonitriles, amido-esters, amidoacyl-chlorides or diacyl-chlorides, c) addition of carbon-monoxide on alpha,beta-unsaturated amides, d) oxidation reactions, e) Michael addition of active methylen compounds on methacrylamide or conjugated amides. Some of the described methods are used for closing glutarimide ring in syntheses of pharmacological active compounds sesbanimide and aldose reductase inhibitors (ARI). Analyses of the geometry, as well as, the spectroscopic analyses (NMR and FT-IR) of some glutarimides are presented due to their broad spectrum of pharmacological activity. To elucidate structures of glutarimides, geometrical parameters of newly synthesized tert-pentyl-1-benzyl-4-methyl-glutarimide-3-carboxylate (PBMG) are analyzed and compared with the experimental data from X-ray analysis for glutarimide. Moreover, molecular electrostatic potential (MEP) surface which is plotted over the optimized geometry to elucidate the reactivity of PBMG molecule is analyzed. The electronic properties of glutarimide derivatives are explained on the example of thalidomide. The Frontier Molecular Orbital (FMO) and their energies are presented, as well as the energy gap between them., U ovom radu dat je prikaz metoda za sintezu šestočlanih cikličnih imida. Glutarimidi, 2,6-dioksopiperidini, su značajna biološka jedinjenja i deluju kao antagonisti adrenogenih receptora, antiinflamatorni agensi, anksiolitici, antivirotici, antibiotici i agensi koji sprečavaju rast pojedinih vrsta tumora. Prikazana je i njihova spektralna analiza (FT-IR i NMR), zbog potvrde stukture, kao i analiza graničnih molekulskih orbitala koja daje prikaz elektronskih svojstava ovih molekula, što je važno zbog njihove biološke aktivnosti. Da bi se predstavila hemijska reaktivnost glutarimida predstavljen je molekulski elektronski potencijal (MEP) iz prethodno optimizovane geometrije reprezentativnog primera terc-pentil-1- -benzil-4-metil-glutarimid-3-karboksilata (skraćenica PBMG). Elektronska svojstva su objašnjena na primeru talidomida.",
publisher = "Assoc Chemical Engineers Serbia, Belgrade",
journal = "Hemijska industrija",
title = "Glutarimides: Biological Activity, General Synthetic Methods and Physicochemical Properties, Glutarimidi - biološka aktivnost, opšti postupci za sintezu i fizičko-hemijske karakteristike",
volume = "69",
number = "5",
pages = "523-536",
doi = "10.2298/HEMIND140701073P",
url = "Kon_2970"
}
Popović-Đorđević, J., Vitnik, V. D., Vitnik, Z. J.,& Ivanović, M.. (2015). Glutarimides: Biological Activity, General Synthetic Methods and Physicochemical Properties. in Hemijska industrija
Assoc Chemical Engineers Serbia, Belgrade., 69(5), 523-536.
https://doi.org/10.2298/HEMIND140701073P
Kon_2970
Popović-Đorđević J, Vitnik VD, Vitnik ZJ, Ivanović M. Glutarimides: Biological Activity, General Synthetic Methods and Physicochemical Properties. in Hemijska industrija. 2015;69(5):523-536.
doi:10.2298/HEMIND140701073P
Kon_2970 .
Popović-Đorđević, Jelena, Vitnik, Vesna D., Vitnik, Zeljko J., Ivanović, Milovan, "Glutarimides: Biological Activity, General Synthetic Methods and Physicochemical Properties" in Hemijska industrija, 69, no. 5 (2015):523-536,
https://doi.org/10.2298/HEMIND140701073P .,
Kon_2970 .
1
1

A novel tandem process leading to functionalized glutarimides

Popović-Đorđević, Jelena; Ivanović, Milovan; Kiricojevic, VD

(Pergamon-Elsevier Science Ltd, Oxford, 2005)

TY  - JOUR
AU  - Popović-Đorđević, Jelena
AU  - Ivanović, Milovan
AU  - Kiricojevic, VD
PY  - 2005
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/691
AB  - The synthesis of various functionalized or spirobicyclic glutarimides by a novel tandem process has been disclosed. The reaction involves a base-catalyzed Michael addition of active methylene compounds to secondary conjugated amides, followed by intramolecular N-acylation of the carboxamido group. It provides a relatively general and simple access to useful synthetic intermediaries and potentially active pharmacological compounds. In addition, a novel group of spirobicyclic systems has been synthesized. (c) 2005 Elsevier Ltd. All rights reserved.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Tetrahedron Letters
T1  - A novel tandem process leading to functionalized glutarimides
VL  - 46
IS  - 15
SP  - 2611
EP  - 2614
DO  - 10.1016/j.tetlet.2005.02.087
UR  - Kon_1644
ER  - 
@article{
author = "Popović-Đorđević, Jelena and Ivanović, Milovan and Kiricojevic, VD",
year = "2005",
abstract = "The synthesis of various functionalized or spirobicyclic glutarimides by a novel tandem process has been disclosed. The reaction involves a base-catalyzed Michael addition of active methylene compounds to secondary conjugated amides, followed by intramolecular N-acylation of the carboxamido group. It provides a relatively general and simple access to useful synthetic intermediaries and potentially active pharmacological compounds. In addition, a novel group of spirobicyclic systems has been synthesized. (c) 2005 Elsevier Ltd. All rights reserved.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Tetrahedron Letters",
title = "A novel tandem process leading to functionalized glutarimides",
volume = "46",
number = "15",
pages = "2611-2614",
doi = "10.1016/j.tetlet.2005.02.087",
url = "Kon_1644"
}
Popović-Đorđević, J., Ivanović, M.,& Kiricojevic, V.. (2005). A novel tandem process leading to functionalized glutarimides. in Tetrahedron Letters
Pergamon-Elsevier Science Ltd, Oxford., 46(15), 2611-2614.
https://doi.org/10.1016/j.tetlet.2005.02.087
Kon_1644
Popović-Đorđević J, Ivanović M, Kiricojevic V. A novel tandem process leading to functionalized glutarimides. in Tetrahedron Letters. 2005;46(15):2611-2614.
doi:10.1016/j.tetlet.2005.02.087
Kon_1644 .
Popović-Đorđević, Jelena, Ivanović, Milovan, Kiricojevic, VD, "A novel tandem process leading to functionalized glutarimides" in Tetrahedron Letters, 46, no. 15 (2005):2611-2614,
https://doi.org/10.1016/j.tetlet.2005.02.087 .,
Kon_1644 .
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