TY  - JOUR
AU  - Dimitrijević, Teodora
AU  - Novaković, Irena T.
AU  - Radanović, Dušanka D.
AU  - Novaković, Sladjana B.
AU  - Rodić, Marko
AU  - Anđelković, Katarina K.
AU  - Šumar-Ristović, Maja
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4025
AB  - In this article, synthesis, spectral and X-ray structure characterization, antimicrobial activity and Brine shrimp test of two new Cu(II) complexes with a salicylaldehyde derivative have been reported. Complexes [Cu(L)(bipy)]BF4·0.5H2O and [Cu2(L)2(phen)2](BF4)2 were obtained in the reaction of Cu(BF4)2·6H2O, deprotonated 4-(diethylamino)−2-hydroxybenzaldehyde ligand (L) and α-diimine (2,2’-bipyridine or 1,10-phenanthroline). The complex with bipyridine is mononuclear, containing one L and one bipyridine ligand in a distorted square-planar cation with a BF4 − anion and lattice water molecule, whereas the complex with phenanthroline is a dinuclear centrosymmetric dimeric cation, containing two L ligands along with two phenanthroline ligands and BF4 − anions. The coordination geometry of each Cu(II) ion can be described as an elongated square pyramid. MS-ESI spectroscopy indicated that [Cu2(L)2(phen)2](BF4)2 is mononuclear in DMSO solution. In vitro antibacterial and antifungal activity was tested against four Gram-positive, four Gram-negative bacteria and three fungal strains. Complexes showed significantly stronger antibacterial activities than parent ligands. The mononuclear phenanthroline complex in solution showed very good antimicrobial activity, which is comparable to the activity of the standard antibiotic amikacin against all tested bacterial strains. The same complex has better antifungal activity than fluconazole, which was used as a standard. Results of the brine shrimp test indicate that both complexes have good toxicity against Artemia nauplii.
PB  - Taylor & Francis
T2  - Journal of Coordination Chemistry
T1  - Synthesis, spectral and structural characterization and biological activity of Cu(II) complexes with 4-(diethylamino)salicylaldehyde and α-diimines
VL  - 73
IS  - 4
SP  - 702
EP  - 716
DO  - 10.1080/00958972.2020.1740212
ER  - 

@article{
author = "Dimitrijević, Teodora and Novaković, Irena T. and Radanović, Dušanka D. and Novaković, Sladjana B. and Rodić, Marko and Anđelković, Katarina K. and Šumar-Ristović, Maja",
year = "2020",
abstract = "In this article, synthesis, spectral and X-ray structure characterization, antimicrobial activity and Brine shrimp test of two new Cu(II) complexes with a salicylaldehyde derivative have been reported. Complexes [Cu(L)(bipy)]BF4·0.5H2O and [Cu2(L)2(phen)2](BF4)2 were obtained in the reaction of Cu(BF4)2·6H2O, deprotonated 4-(diethylamino)−2-hydroxybenzaldehyde ligand (L) and α-diimine (2,2’-bipyridine or 1,10-phenanthroline). The complex with bipyridine is mononuclear, containing one L and one bipyridine ligand in a distorted square-planar cation with a BF4 − anion and lattice water molecule, whereas the complex with phenanthroline is a dinuclear centrosymmetric dimeric cation, containing two L ligands along with two phenanthroline ligands and BF4 − anions. The coordination geometry of each Cu(II) ion can be described as an elongated square pyramid. MS-ESI spectroscopy indicated that [Cu2(L)2(phen)2](BF4)2 is mononuclear in DMSO solution. In vitro antibacterial and antifungal activity was tested against four Gram-positive, four Gram-negative bacteria and three fungal strains. Complexes showed significantly stronger antibacterial activities than parent ligands. The mononuclear phenanthroline complex in solution showed very good antimicrobial activity, which is comparable to the activity of the standard antibiotic amikacin against all tested bacterial strains. The same complex has better antifungal activity than fluconazole, which was used as a standard. Results of the brine shrimp test indicate that both complexes have good toxicity against Artemia nauplii.",
publisher = "Taylor & Francis",
journal = "Journal of Coordination Chemistry",
title = "Synthesis, spectral and structural characterization and biological activity of Cu(II) complexes with 4-(diethylamino)salicylaldehyde and α-diimines",
volume = "73",
number = "4",
pages = "702-716",
doi = "10.1080/00958972.2020.1740212"
}

Dimitrijević, T., Novaković, I. T., Radanović, D. D., Novaković, S. B., Rodić, M., Anđelković, K. K.,& Šumar-Ristović, M.. (2020). Synthesis, spectral and structural characterization and biological activity of Cu(II) complexes with 4-(diethylamino)salicylaldehyde and α-diimines. in Journal of Coordination Chemistry
Taylor & Francis., 73(4), 702-716.
https://doi.org/10.1080/00958972.2020.1740212

Dimitrijević T, Novaković IT, Radanović DD, Novaković SB, Rodić M, Anđelković KK, Šumar-Ristović M. Synthesis, spectral and structural characterization and biological activity of Cu(II) complexes with 4-(diethylamino)salicylaldehyde and α-diimines. in Journal of Coordination Chemistry. 2020;73(4):702-716.
doi:10.1080/00958972.2020.1740212 .

Dimitrijević, Teodora, Novaković, Irena T., Radanović, Dušanka D., Novaković, Sladjana B., Rodić, Marko, Anđelković, Katarina K., Šumar-Ristović, Maja, "Synthesis, spectral and structural characterization and biological activity of Cu(II) complexes with 4-(diethylamino)salicylaldehyde and α-diimines" in Journal of Coordination Chemistry, 73, no. 4 (2020):702-716,
https://doi.org/10.1080/00958972.2020.1740212 . .

TY  - DATA
AU  - Dimitrijević, Teodora
AU  - Novaković, Irena T.
AU  - Radanović, Dušanka D.
AU  - Novaković, Sladjana B.
AU  - Rodić, Marko
AU  - Anđelković, Katarina K.
AU  - Šumar-Ristović, Maja
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4026
PB  - Taylor & Francis
T2  - Journal of Coordination Chemistry
T1  - Supplementary data for the article: Dimitrijević, T.; Novaković, I.; Radanović, D.; Novaković, S. B.; Rodić, M. V.; Anđelković, K.; Šumar-Ristović, M. Synthesis, Spectral and Structural Characterization and Biological Activity of Cu(II) Complexes with 4-(Diethylamino)Salicylaldehyde and α-Diimines. Journal of Coordination Chemistry 2020, 73 (4), 702–716. https://doi.org/10.1080/00958972.2020.1740212
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4026
ER  - 

@misc{
author = "Dimitrijević, Teodora and Novaković, Irena T. and Radanović, Dušanka D. and Novaković, Sladjana B. and Rodić, Marko and Anđelković, Katarina K. and Šumar-Ristović, Maja",
year = "2020",
publisher = "Taylor & Francis",
journal = "Journal of Coordination Chemistry",
title = "Supplementary data for the article: Dimitrijević, T.; Novaković, I.; Radanović, D.; Novaković, S. B.; Rodić, M. V.; Anđelković, K.; Šumar-Ristović, M. Synthesis, Spectral and Structural Characterization and Biological Activity of Cu(II) Complexes with 4-(Diethylamino)Salicylaldehyde and α-Diimines. Journal of Coordination Chemistry 2020, 73 (4), 702–716. https://doi.org/10.1080/00958972.2020.1740212",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4026"
}

Dimitrijević, T., Novaković, I. T., Radanović, D. D., Novaković, S. B., Rodić, M., Anđelković, K. K.,& Šumar-Ristović, M.. (2020). Supplementary data for the article: Dimitrijević, T.; Novaković, I.; Radanović, D.; Novaković, S. B.; Rodić, M. V.; Anđelković, K.; Šumar-Ristović, M. Synthesis, Spectral and Structural Characterization and Biological Activity of Cu(II) Complexes with 4-(Diethylamino)Salicylaldehyde and α-Diimines. Journal of Coordination Chemistry 2020, 73 (4), 702–716. https://doi.org/10.1080/00958972.2020.1740212. in Journal of Coordination Chemistry
Taylor & Francis..
https://hdl.handle.net/21.15107/rcub_cherry_4026

Dimitrijević T, Novaković IT, Radanović DD, Novaković SB, Rodić M, Anđelković KK, Šumar-Ristović M. Supplementary data for the article: Dimitrijević, T.; Novaković, I.; Radanović, D.; Novaković, S. B.; Rodić, M. V.; Anđelković, K.; Šumar-Ristović, M. Synthesis, Spectral and Structural Characterization and Biological Activity of Cu(II) Complexes with 4-(Diethylamino)Salicylaldehyde and α-Diimines. Journal of Coordination Chemistry 2020, 73 (4), 702–716. https://doi.org/10.1080/00958972.2020.1740212. in Journal of Coordination Chemistry. 2020;.
https://hdl.handle.net/21.15107/rcub_cherry_4026 .

Dimitrijević, Teodora, Novaković, Irena T., Radanović, Dušanka D., Novaković, Sladjana B., Rodić, Marko, Anđelković, Katarina K., Šumar-Ristović, Maja, "Supplementary data for the article: Dimitrijević, T.; Novaković, I.; Radanović, D.; Novaković, S. B.; Rodić, M. V.; Anđelković, K.; Šumar-Ristović, M. Synthesis, Spectral and Structural Characterization and Biological Activity of Cu(II) Complexes with 4-(Diethylamino)Salicylaldehyde and α-Diimines. Journal of Coordination Chemistry 2020, 73 (4), 702–716. https://doi.org/10.1080/00958972.2020.1740212" in Journal of Coordination Chemistry (2020),
https://hdl.handle.net/21.15107/rcub_cherry_4026 .

TY  - JOUR
AU  - Petković, Branka B.
AU  - Kuzmanović, Darko
AU  - Dimitrijević, Teodora
AU  - Krstic, M. P.
AU  - Stanković, Dalibor
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2465
AB  - A simple and fast method for determination of two phenothiazine drugs, chlorpromazine (CPZ) and thioridazine (TDZ), at the boron-doped diamond electrode (BDDE) was proposed. Oxidation peaks on potentials higher than 1 V were used for quantitation of investigated phenothiazines due to better selectivity over common interfering compounds in urine. Differential pulse voltammetry was applied for trace determination of CPZ and TDZ, in Britton-Robinson buffer solution at optimal pH. Under optimized DPV conditions a linear analytical curve was obtained from 1.0x10(-7) to 4.0x10(-5) M with a detection limit of 0.3x10(-7) M (for CPZ) and in the concentration range of 2x10(-7) M to 4.0x10(-5) M, with a detection limit of 1.2x10(-7)M (for TDZ). The applicability of the method was proved by determination of CPZ and TDZ by proposed procedures in spiked urine samples. The electrochemical behavior of those two important tranquilizers in different solvents was described, exploring the possibility of simultaneous determination.
PB  - Esg, Belgrade
T2  - International Journal of Electrochemical Science
T1  - Novel Strategy for Electroanalytical Detection of Antipsychotic Drugs Chlorpromazine and Thioridazine; Possibilities for Simultaneous Determination
VL  - 12
IS  - 5
SP  - 3709
EP  - 3720
DO  - 10.20964/2017.05.34
ER  - 

@article{
author = "Petković, Branka B. and Kuzmanović, Darko and Dimitrijević, Teodora and Krstic, M. P. and Stanković, Dalibor",
year = "2017",
abstract = "A simple and fast method for determination of two phenothiazine drugs, chlorpromazine (CPZ) and thioridazine (TDZ), at the boron-doped diamond electrode (BDDE) was proposed. Oxidation peaks on potentials higher than 1 V were used for quantitation of investigated phenothiazines due to better selectivity over common interfering compounds in urine. Differential pulse voltammetry was applied for trace determination of CPZ and TDZ, in Britton-Robinson buffer solution at optimal pH. Under optimized DPV conditions a linear analytical curve was obtained from 1.0x10(-7) to 4.0x10(-5) M with a detection limit of 0.3x10(-7) M (for CPZ) and in the concentration range of 2x10(-7) M to 4.0x10(-5) M, with a detection limit of 1.2x10(-7)M (for TDZ). The applicability of the method was proved by determination of CPZ and TDZ by proposed procedures in spiked urine samples. The electrochemical behavior of those two important tranquilizers in different solvents was described, exploring the possibility of simultaneous determination.",
publisher = "Esg, Belgrade",
journal = "International Journal of Electrochemical Science",
title = "Novel Strategy for Electroanalytical Detection of Antipsychotic Drugs Chlorpromazine and Thioridazine; Possibilities for Simultaneous Determination",
volume = "12",
number = "5",
pages = "3709-3720",
doi = "10.20964/2017.05.34"
}

Petković, B. B., Kuzmanović, D., Dimitrijević, T., Krstic, M. P.,& Stanković, D.. (2017). Novel Strategy for Electroanalytical Detection of Antipsychotic Drugs Chlorpromazine and Thioridazine; Possibilities for Simultaneous Determination. in International Journal of Electrochemical Science
Esg, Belgrade., 12(5), 3709-3720.
https://doi.org/10.20964/2017.05.34

Petković BB, Kuzmanović D, Dimitrijević T, Krstic MP, Stanković D. Novel Strategy for Electroanalytical Detection of Antipsychotic Drugs Chlorpromazine and Thioridazine; Possibilities for Simultaneous Determination. in International Journal of Electrochemical Science. 2017;12(5):3709-3720.
doi:10.20964/2017.05.34 .

Petković, Branka B., Kuzmanović, Darko, Dimitrijević, Teodora, Krstic, M. P., Stanković, Dalibor, "Novel Strategy for Electroanalytical Detection of Antipsychotic Drugs Chlorpromazine and Thioridazine; Possibilities for Simultaneous Determination" in International Journal of Electrochemical Science, 12, no. 5 (2017):3709-3720,
https://doi.org/10.20964/2017.05.34 . .

TY  - JOUR
AU  - Dimitrijević, Teodora
AU  - Vulić, Predrag J.
AU  - Manojlović, Dragan D.
AU  - Nikolić, Aleksandar S.
AU  - Stanković, Dalibor
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1950
AB  - In this study, a novel electrochemical sensor for quantification of ascorbic acid with amperometric detection in physiological conditions was constructed. For this purpose, cobalt and nickel ferrites were synthesized using microwave and ultrasound assistance, characterized by scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, and X-ray powder diffraction (XRPD), and used for modification of glassy carbon paste electrode (GCPE). It was shown that introducing these nanoparticles to the structure of GCPE led to increasing analytical performance. Co ferrite modified GCPE (CoFeGCPE) showed better characteristics toward ascorbic acid sensing. The limit of detection (LOD) obtained by sensor was calculated to be 0.0270 mg/L, with linear range from 0.1758 to 2.6010 mg/L. This sensor was successfully applied for practical analysis, and the obtained results demonstrated that the proposed procedure could be a promising replacement for the conventional electrode materials and time-consuming and expensive separation methods. (C) 2016 Elsevier Inc. All rights reserved.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Analytical Biochemistry
T1  - Amperometric ascorbic acid sensor based on doped ferrites nanoparticles modified glassy carbon paste electrode
VL  - 504
SP  - 20
EP  - 26
DO  - 10.1016/j.ab.2016.03.020
ER  - 

@article{
author = "Dimitrijević, Teodora and Vulić, Predrag J. and Manojlović, Dragan D. and Nikolić, Aleksandar S. and Stanković, Dalibor",
year = "2016",
abstract = "In this study, a novel electrochemical sensor for quantification of ascorbic acid with amperometric detection in physiological conditions was constructed. For this purpose, cobalt and nickel ferrites were synthesized using microwave and ultrasound assistance, characterized by scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, and X-ray powder diffraction (XRPD), and used for modification of glassy carbon paste electrode (GCPE). It was shown that introducing these nanoparticles to the structure of GCPE led to increasing analytical performance. Co ferrite modified GCPE (CoFeGCPE) showed better characteristics toward ascorbic acid sensing. The limit of detection (LOD) obtained by sensor was calculated to be 0.0270 mg/L, with linear range from 0.1758 to 2.6010 mg/L. This sensor was successfully applied for practical analysis, and the obtained results demonstrated that the proposed procedure could be a promising replacement for the conventional electrode materials and time-consuming and expensive separation methods. (C) 2016 Elsevier Inc. All rights reserved.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Analytical Biochemistry",
title = "Amperometric ascorbic acid sensor based on doped ferrites nanoparticles modified glassy carbon paste electrode",
volume = "504",
pages = "20-26",
doi = "10.1016/j.ab.2016.03.020"
}

Dimitrijević, T., Vulić, P. J., Manojlović, D. D., Nikolić, A. S.,& Stanković, D.. (2016). Amperometric ascorbic acid sensor based on doped ferrites nanoparticles modified glassy carbon paste electrode. in Analytical Biochemistry
Academic Press Inc Elsevier Science, San Diego., 504, 20-26.
https://doi.org/10.1016/j.ab.2016.03.020

Dimitrijević T, Vulić PJ, Manojlović DD, Nikolić AS, Stanković D. Amperometric ascorbic acid sensor based on doped ferrites nanoparticles modified glassy carbon paste electrode. in Analytical Biochemistry. 2016;504:20-26.
doi:10.1016/j.ab.2016.03.020 .

Dimitrijević, Teodora, Vulić, Predrag J., Manojlović, Dragan D., Nikolić, Aleksandar S., Stanković, Dalibor, "Amperometric ascorbic acid sensor based on doped ferrites nanoparticles modified glassy carbon paste electrode" in Analytical Biochemistry, 504 (2016):20-26,
https://doi.org/10.1016/j.ab.2016.03.020 . .

TY  - DATA
AU  - Dimitrijević, Teodora
AU  - Vulić, Predrag J.
AU  - Manojlović, Dragan D.
AU  - Nikolić, Aleksandar S.
AU  - Stanković, Dalibor
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3336
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Analytical Biochemistry
T1  - Supplementary data for the article: Dimitrijević, T.; Vulić, P.; Manojlović, D.; Nikolić, A. S.; Stanković, D. M. Amperometric Ascorbic Acid Sensor Based on Doped Ferrites Nanoparticles Modified Glassy Carbon Paste Electrode. Analytical Biochemistry 2016, 504, 20–26. https://doi.org/10.1016/j.ab.2016.03.020
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3336
ER  - 

@misc{
author = "Dimitrijević, Teodora and Vulić, Predrag J. and Manojlović, Dragan D. and Nikolić, Aleksandar S. and Stanković, Dalibor",
year = "2016",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Analytical Biochemistry",
title = "Supplementary data for the article: Dimitrijević, T.; Vulić, P.; Manojlović, D.; Nikolić, A. S.; Stanković, D. M. Amperometric Ascorbic Acid Sensor Based on Doped Ferrites Nanoparticles Modified Glassy Carbon Paste Electrode. Analytical Biochemistry 2016, 504, 20–26. https://doi.org/10.1016/j.ab.2016.03.020",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3336"
}

Dimitrijević, T., Vulić, P. J., Manojlović, D. D., Nikolić, A. S.,& Stanković, D.. (2016). Supplementary data for the article: Dimitrijević, T.; Vulić, P.; Manojlović, D.; Nikolić, A. S.; Stanković, D. M. Amperometric Ascorbic Acid Sensor Based on Doped Ferrites Nanoparticles Modified Glassy Carbon Paste Electrode. Analytical Biochemistry 2016, 504, 20–26. https://doi.org/10.1016/j.ab.2016.03.020. in Analytical Biochemistry
Academic Press Inc Elsevier Science, San Diego..
https://hdl.handle.net/21.15107/rcub_cherry_3336

Dimitrijević T, Vulić PJ, Manojlović DD, Nikolić AS, Stanković D. Supplementary data for the article: Dimitrijević, T.; Vulić, P.; Manojlović, D.; Nikolić, A. S.; Stanković, D. M. Amperometric Ascorbic Acid Sensor Based on Doped Ferrites Nanoparticles Modified Glassy Carbon Paste Electrode. Analytical Biochemistry 2016, 504, 20–26. https://doi.org/10.1016/j.ab.2016.03.020. in Analytical Biochemistry. 2016;.
https://hdl.handle.net/21.15107/rcub_cherry_3336 .

Dimitrijević, Teodora, Vulić, Predrag J., Manojlović, Dragan D., Nikolić, Aleksandar S., Stanković, Dalibor, "Supplementary data for the article: Dimitrijević, T.; Vulić, P.; Manojlović, D.; Nikolić, A. S.; Stanković, D. M. Amperometric Ascorbic Acid Sensor Based on Doped Ferrites Nanoparticles Modified Glassy Carbon Paste Electrode. Analytical Biochemistry 2016, 504, 20–26. https://doi.org/10.1016/j.ab.2016.03.020" in Analytical Biochemistry (2016),
https://hdl.handle.net/21.15107/rcub_cherry_3336 .

TY  - CONF
AU  - Dimitrijević, Teodora
AU  - Kuzmanović, Darko
AU  - Roglić, Goran
AU  - Manojlović, Dragan D.
AU  - Stanković, Dalibor
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2812
PB  - Novi Sad : Alfagraf
C3  - Book of abstracts / 23rd Young Investigators' Seminar on Analytical Chemistry, June 28th-July 1st 2016, Novi Sad, Serbia
T1  - Voltammetric determination of piperidine type drugs at boron-doped diamond electrode
SP  - 10
EP  - 10
UR  - https://hdl.handle.net/21.15107/rcub_cherry_2812
ER  - 

@conference{
author = "Dimitrijević, Teodora and Kuzmanović, Darko and Roglić, Goran and Manojlović, Dragan D. and Stanković, Dalibor",
year = "2016",
publisher = "Novi Sad : Alfagraf",
journal = "Book of abstracts / 23rd Young Investigators' Seminar on Analytical Chemistry, June 28th-July 1st 2016, Novi Sad, Serbia",
title = "Voltammetric determination of piperidine type drugs at boron-doped diamond electrode",
pages = "10-10",
url = "https://hdl.handle.net/21.15107/rcub_cherry_2812"
}

Dimitrijević, T., Kuzmanović, D., Roglić, G., Manojlović, D. D.,& Stanković, D.. (2016). Voltammetric determination of piperidine type drugs at boron-doped diamond electrode. in Book of abstracts / 23rd Young Investigators' Seminar on Analytical Chemistry, June 28th-July 1st 2016, Novi Sad, Serbia
Novi Sad : Alfagraf., 10-10.
https://hdl.handle.net/21.15107/rcub_cherry_2812

Dimitrijević T, Kuzmanović D, Roglić G, Manojlović DD, Stanković D. Voltammetric determination of piperidine type drugs at boron-doped diamond electrode. in Book of abstracts / 23rd Young Investigators' Seminar on Analytical Chemistry, June 28th-July 1st 2016, Novi Sad, Serbia. 2016;:10-10.
https://hdl.handle.net/21.15107/rcub_cherry_2812 .

Dimitrijević, Teodora, Kuzmanović, Darko, Roglić, Goran, Manojlović, Dragan D., Stanković, Dalibor, "Voltammetric determination of piperidine type drugs at boron-doped diamond electrode" in Book of abstracts / 23rd Young Investigators' Seminar on Analytical Chemistry, June 28th-July 1st 2016, Novi Sad, Serbia (2016):10-10,
https://hdl.handle.net/21.15107/rcub_cherry_2812 .

TY  - JOUR
AU  - Stanković, Dalibor
AU  - Dimitrijević, Teodora
AU  - Kuzmanović, Darko
AU  - Krstic, M. P.
AU  - Petković, Branka B.
PY  - 2015
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2018
AB  - A simple and efficient procedure is described for electrochemical determination of trifluoperazine (TFP), a prominent compound in a large group of phenothiazine derivatives with potent physiological activity. This method is based on the electrochemical oxidation of TFP in Britton-Robinson buffer solution in pH 6 at a boron-doped diamond electrode. Cyclic voltammetry provided a four well defined oxidation peaks at + 0.65, + 0.83, + 1.06 and + 1.35 V (vs. Ag/AgCl/3 M KCl electrode). Differential pulse voltammetry was applied as a very sensitive analytical technique for the determination of micromolar amounts of TFP. Two oxidation peaks on higher potentials were chosen for quantification of TFP. Under optimized conditions, the analytical curves obtained were linear in the TFP concentration range of 1.0 to 37.0 mmol L-1, with a detection limit of 0.7 and 0.6 mmol L-1, respectively. The effect of interfering agents (common urinary compounds) appeared to be negligible confirming the favourable selectivity of the method. The proposed method was analytically applied by determination of trifluoperazine content in model human urine samples with good accuracy (recoveries varied from 97% to 104%). The developed approach could be beneficial in analysis of TFP in biological samples using a boron-doped diamond electrode as an up-to-date electrochemical sensor and could represent an inexpensive analytical alternative to separation methods.
PB  - Royal Soc Chemistry, Cambridge
T2  - RSC Advances
T1  - Voltammetric determination of an antipsychotic agent trifluoperazine at a boron-doped diamond electrode in human urine
VL  - 5
IS  - 129
SP  - 107058
EP  - 107063
DO  - 10.1039/c5ra18783d
ER  - 

@article{
author = "Stanković, Dalibor and Dimitrijević, Teodora and Kuzmanović, Darko and Krstic, M. P. and Petković, Branka B.",
year = "2015",
abstract = "A simple and efficient procedure is described for electrochemical determination of trifluoperazine (TFP), a prominent compound in a large group of phenothiazine derivatives with potent physiological activity. This method is based on the electrochemical oxidation of TFP in Britton-Robinson buffer solution in pH 6 at a boron-doped diamond electrode. Cyclic voltammetry provided a four well defined oxidation peaks at + 0.65, + 0.83, + 1.06 and + 1.35 V (vs. Ag/AgCl/3 M KCl electrode). Differential pulse voltammetry was applied as a very sensitive analytical technique for the determination of micromolar amounts of TFP. Two oxidation peaks on higher potentials were chosen for quantification of TFP. Under optimized conditions, the analytical curves obtained were linear in the TFP concentration range of 1.0 to 37.0 mmol L-1, with a detection limit of 0.7 and 0.6 mmol L-1, respectively. The effect of interfering agents (common urinary compounds) appeared to be negligible confirming the favourable selectivity of the method. The proposed method was analytically applied by determination of trifluoperazine content in model human urine samples with good accuracy (recoveries varied from 97% to 104%). The developed approach could be beneficial in analysis of TFP in biological samples using a boron-doped diamond electrode as an up-to-date electrochemical sensor and could represent an inexpensive analytical alternative to separation methods.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "RSC Advances",
title = "Voltammetric determination of an antipsychotic agent trifluoperazine at a boron-doped diamond electrode in human urine",
volume = "5",
number = "129",
pages = "107058-107063",
doi = "10.1039/c5ra18783d"
}

Stanković, D., Dimitrijević, T., Kuzmanović, D., Krstic, M. P.,& Petković, B. B.. (2015). Voltammetric determination of an antipsychotic agent trifluoperazine at a boron-doped diamond electrode in human urine. in RSC Advances
Royal Soc Chemistry, Cambridge., 5(129), 107058-107063.
https://doi.org/10.1039/c5ra18783d

Stanković D, Dimitrijević T, Kuzmanović D, Krstic MP, Petković BB. Voltammetric determination of an antipsychotic agent trifluoperazine at a boron-doped diamond electrode in human urine. in RSC Advances. 2015;5(129):107058-107063.
doi:10.1039/c5ra18783d .

Stanković, Dalibor, Dimitrijević, Teodora, Kuzmanović, Darko, Krstic, M. P., Petković, Branka B., "Voltammetric determination of an antipsychotic agent trifluoperazine at a boron-doped diamond electrode in human urine" in RSC Advances, 5, no. 129 (2015):107058-107063,
https://doi.org/10.1039/c5ra18783d . .