TY  - JOUR
AU  - Andrić, Filip
AU  - Šegan, Sandra B.
AU  - Dramićanin, Aleksandra M.
AU  - Majstorović, Helena
AU  - Milojković-Opsenica, Dušanka
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2288
AB  - Soil-water partition coefficient normalized to the organic carbon.content (K-OC) is one of the crucial properties influencing the fate of organic compounds in the environment. Chromatographic methods are well established alternative for direct sorption techniques used for K-OC determination. The present work proposes reversed-phase thin-layer chromatography (RP-TLC) as a simpler, yet equally accurate method as officially recommended HPLC technique. Several TLC systems were studied including octadecyl-(RP18) and cyano-(CN) modified silica layers in combination with methanol-water and acetonitrile-water mixtures as mobile phases. In total 50 compounds of different molecular shape, size, and various ability to establish specific interactions were selected (phenols, beznodiazepines, triazine herbicides, and polyaromatic hydrocarbons). Calibration set of 29 compounds with known logK(OC) values determined by sorption experiments was used to build simple univariate calibrations, Principal Component Regression (PCR) and Partial Least Squares (PLS) models between logK(OC) and TLC retention parameters. Models exhibit good statistical performance, indicating that CN-layers contribute better to logK(OC) modeling than RP18-silica. The most promising TLC methods, officially recommended HPLC method, and four in silico estimation approaches have been compared by non-parametric Sum of Ranking Differences approach (SRD). The best estimations of logK(OC) values were achieved by simple univariate calibration of TLC retention data involving CN-silica layers and moderate content of methanol (40-50% v/v). They were ranked far well compared to the officially recommended HPLC method which was ranked in the middle. The worst estimates have been obtained from in silico computations based on octanol-water partition coefficient. Linear Solvation Energy Relationship study revealed that increased polarity of CN-layers over RP18 in combination with methanol-water mixtures is the key to better modeling of logK(OC) through significant diminishing of dipolar and proton accepting influence of the mobile phase as well as enhancing molar refractivity in excess of the chromatographic systems. (C) 2016 Elsevier B.V. All rights reserved.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Chromatography A
T1  - Linear modeling of the soil-water partition coefficient normalized to organic carbon content by reversed-phase thin-layer chromatography
VL  - 1458
SP  - 136
EP  - 144
DO  - 10.1016/j.chroma.2016.06.063
ER  - 

@article{
author = "Andrić, Filip and Šegan, Sandra B. and Dramićanin, Aleksandra M. and Majstorović, Helena and Milojković-Opsenica, Dušanka",
year = "2016",
abstract = "Soil-water partition coefficient normalized to the organic carbon.content (K-OC) is one of the crucial properties influencing the fate of organic compounds in the environment. Chromatographic methods are well established alternative for direct sorption techniques used for K-OC determination. The present work proposes reversed-phase thin-layer chromatography (RP-TLC) as a simpler, yet equally accurate method as officially recommended HPLC technique. Several TLC systems were studied including octadecyl-(RP18) and cyano-(CN) modified silica layers in combination with methanol-water and acetonitrile-water mixtures as mobile phases. In total 50 compounds of different molecular shape, size, and various ability to establish specific interactions were selected (phenols, beznodiazepines, triazine herbicides, and polyaromatic hydrocarbons). Calibration set of 29 compounds with known logK(OC) values determined by sorption experiments was used to build simple univariate calibrations, Principal Component Regression (PCR) and Partial Least Squares (PLS) models between logK(OC) and TLC retention parameters. Models exhibit good statistical performance, indicating that CN-layers contribute better to logK(OC) modeling than RP18-silica. The most promising TLC methods, officially recommended HPLC method, and four in silico estimation approaches have been compared by non-parametric Sum of Ranking Differences approach (SRD). The best estimations of logK(OC) values were achieved by simple univariate calibration of TLC retention data involving CN-silica layers and moderate content of methanol (40-50% v/v). They were ranked far well compared to the officially recommended HPLC method which was ranked in the middle. The worst estimates have been obtained from in silico computations based on octanol-water partition coefficient. Linear Solvation Energy Relationship study revealed that increased polarity of CN-layers over RP18 in combination with methanol-water mixtures is the key to better modeling of logK(OC) through significant diminishing of dipolar and proton accepting influence of the mobile phase as well as enhancing molar refractivity in excess of the chromatographic systems. (C) 2016 Elsevier B.V. All rights reserved.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Chromatography A",
title = "Linear modeling of the soil-water partition coefficient normalized to organic carbon content by reversed-phase thin-layer chromatography",
volume = "1458",
pages = "136-144",
doi = "10.1016/j.chroma.2016.06.063"
}

Andrić, F., Šegan, S. B., Dramićanin, A. M., Majstorović, H.,& Milojković-Opsenica, D.. (2016). Linear modeling of the soil-water partition coefficient normalized to organic carbon content by reversed-phase thin-layer chromatography. in Journal of Chromatography A
Elsevier Science Bv, Amsterdam., 1458, 136-144.
https://doi.org/10.1016/j.chroma.2016.06.063

Andrić F, Šegan SB, Dramićanin AM, Majstorović H, Milojković-Opsenica D. Linear modeling of the soil-water partition coefficient normalized to organic carbon content by reversed-phase thin-layer chromatography. in Journal of Chromatography A. 2016;1458:136-144.
doi:10.1016/j.chroma.2016.06.063 .

Andrić, Filip, Šegan, Sandra B., Dramićanin, Aleksandra M., Majstorović, Helena, Milojković-Opsenica, Dušanka, "Linear modeling of the soil-water partition coefficient normalized to organic carbon content by reversed-phase thin-layer chromatography" in Journal of Chromatography A, 1458 (2016):136-144,
https://doi.org/10.1016/j.chroma.2016.06.063 . .

TY  - JOUR
AU  - Milojković-Opsenica, Dušanka
AU  - Majstorović, Helena
AU  - Radoičić, Aleksandra
AU  - Tešić, Živoslav Lj.
PY  - 2015
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1686
AB  - An overview of the adsorption characteristics of 3-cyanopropylsiloxane-bonded silica gel as a specific, moderately polar sorbent which can be used for separation of different classes of organic and inorganic substances in both normal- and reversed-phase chromatography is presented. The most important separation mechanisms that govern the retention on this sorbent are underlined. In addition, some recently published applications of 3-cyanopropylsiloxane-bonded silica gel as a sorbent in thin-layer chromatography are listed.
PB  - Akademiai Kiado Rt, Budapest
T2  - Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
T1  - 3-Cyanopropylsiloxane-Bonded Silica Gel: Characteristics and Applications in Thin-Layer Chromatography
VL  - 28
IS  - 2
SP  - 106
EP  - 114
DO  - 10.1556/JPC.28.2015.2.4
ER  - 

@article{
author = "Milojković-Opsenica, Dušanka and Majstorović, Helena and Radoičić, Aleksandra and Tešić, Živoslav Lj.",
year = "2015",
abstract = "An overview of the adsorption characteristics of 3-cyanopropylsiloxane-bonded silica gel as a specific, moderately polar sorbent which can be used for separation of different classes of organic and inorganic substances in both normal- and reversed-phase chromatography is presented. The most important separation mechanisms that govern the retention on this sorbent are underlined. In addition, some recently published applications of 3-cyanopropylsiloxane-bonded silica gel as a sorbent in thin-layer chromatography are listed.",
publisher = "Akademiai Kiado Rt, Budapest",
journal = "Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography",
title = "3-Cyanopropylsiloxane-Bonded Silica Gel: Characteristics and Applications in Thin-Layer Chromatography",
volume = "28",
number = "2",
pages = "106-114",
doi = "10.1556/JPC.28.2015.2.4"
}

Milojković-Opsenica, D., Majstorović, H., Radoičić, A.,& Tešić, Ž. Lj.. (2015). 3-Cyanopropylsiloxane-Bonded Silica Gel: Characteristics and Applications in Thin-Layer Chromatography. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
Akademiai Kiado Rt, Budapest., 28(2), 106-114.
https://doi.org/10.1556/JPC.28.2015.2.4

Milojković-Opsenica D, Majstorović H, Radoičić A, Tešić ŽL. 3-Cyanopropylsiloxane-Bonded Silica Gel: Characteristics and Applications in Thin-Layer Chromatography. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography. 2015;28(2):106-114.
doi:10.1556/JPC.28.2015.2.4 .

Milojković-Opsenica, Dušanka, Majstorović, Helena, Radoičić, Aleksandra, Tešić, Živoslav Lj., "3-Cyanopropylsiloxane-Bonded Silica Gel: Characteristics and Applications in Thin-Layer Chromatography" in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography, 28, no. 2 (2015):106-114,
https://doi.org/10.1556/JPC.28.2015.2.4 . .

TY  - JOUR
AU  - Radoičić, Aleksandra
AU  - Majstorović, Helena
AU  - Sabo, Tibor
AU  - Tešić, Živoslav Lj.
AU  - Milojković-Opsenica, Dušanka
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1011
AB  - The chromatographic behavior of twelve neutral, mixed cobalt(III) complexes of the uns-cis-edda-type has been investigated in six planar chromatographic systems. Four different stationary phases unmodified silica gel, CN-silica, cellulose, and alumina - were combined with water-organic solvent (methanol or acetone) binary mobile phases. The effect of the water content of the mobile phases on retention of the complexes was investigation systematically. On the basis of the results obtained, possible separation mechanisms were considered. Hydrophilic-interaction chromatography was assumed to be the mechanism determining separation tinder normal-phase conditions, i.e. use of mobile phases containing small amounts of water. Reversed-phase chromatography occurs when water-rich mobile phases are used.
PB  - Research Inst Medicinal Plants, Budakalasz
T2  - Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
T1  - Hydrophilic-Interaction Planar Chromatography of Some Water-Soluble Co(III) Complexes on Different Adsorbents
VL  - 22
IS  - 4
SP  - 249
EP  - 253
DO  - 10.1556/JPC.22.2009.4.3
ER  - 

@article{
author = "Radoičić, Aleksandra and Majstorović, Helena and Sabo, Tibor and Tešić, Živoslav Lj. and Milojković-Opsenica, Dušanka",
year = "2009",
abstract = "The chromatographic behavior of twelve neutral, mixed cobalt(III) complexes of the uns-cis-edda-type has been investigated in six planar chromatographic systems. Four different stationary phases unmodified silica gel, CN-silica, cellulose, and alumina - were combined with water-organic solvent (methanol or acetone) binary mobile phases. The effect of the water content of the mobile phases on retention of the complexes was investigation systematically. On the basis of the results obtained, possible separation mechanisms were considered. Hydrophilic-interaction chromatography was assumed to be the mechanism determining separation tinder normal-phase conditions, i.e. use of mobile phases containing small amounts of water. Reversed-phase chromatography occurs when water-rich mobile phases are used.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography",
title = "Hydrophilic-Interaction Planar Chromatography of Some Water-Soluble Co(III) Complexes on Different Adsorbents",
volume = "22",
number = "4",
pages = "249-253",
doi = "10.1556/JPC.22.2009.4.3"
}

Radoičić, A., Majstorović, H., Sabo, T., Tešić, Ž. Lj.,& Milojković-Opsenica, D.. (2009). Hydrophilic-Interaction Planar Chromatography of Some Water-Soluble Co(III) Complexes on Different Adsorbents. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
Research Inst Medicinal Plants, Budakalasz., 22(4), 249-253.
https://doi.org/10.1556/JPC.22.2009.4.3

Radoičić A, Majstorović H, Sabo T, Tešić ŽL, Milojković-Opsenica D. Hydrophilic-Interaction Planar Chromatography of Some Water-Soluble Co(III) Complexes on Different Adsorbents. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography. 2009;22(4):249-253.
doi:10.1556/JPC.22.2009.4.3 .

Radoičić, Aleksandra, Majstorović, Helena, Sabo, Tibor, Tešić, Živoslav Lj., Milojković-Opsenica, Dušanka, "Hydrophilic-Interaction Planar Chromatography of Some Water-Soluble Co(III) Complexes on Different Adsorbents" in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography, 22, no. 4 (2009):249-253,
https://doi.org/10.1556/JPC.22.2009.4.3 . .

TY  - JOUR
AU  - Majstorović, Helena
AU  - Ratkov-Zebeljan, D
AU  - Tešić, Živoslav Lj.
AU  - Milojković-Opsenica, Dušanka
PY  - 2004
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/585
AB  - The chromatographic behavior of some phenolic compounds has been studied with the objective of understanding the role of cyano groups in the processes of chromatographic separation on thin layers of CN-silica gel. For this purpose separations were performed on thin layers of CN-silica gel, unmodified silica gel, and polyacrylonitrile adsorbent (PANS) using fourteen mobile phases, nine of which resulted in normal-phase systems. On the basis of the results obtained the effect of compound structure (i.e. properties of ortho substituents of the compounds separated) on their retention is discussed. The dependence of the order of retention of the phenols on the properties of the adsorbent was also considered. Plots of retention data (R-M against R-M) determined by use of different chromatographic systems were used to characterize the systems used. The results enabled hypotheses to be formulated about possible mechanisms involved in the separations of the phenols on these adsorbents.
PB  - Research Inst Medicinal Plants, Budakalasz
T2  - Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
T1  - Interpretation of the mechanisms of chromatographic separation on CN-silica. Part II. TLC of some phenols
VL  - 17
IS  - 1
SP  - 9
EP  - 13
DO  - 10.1556/JPC.17.2004.1.2
ER  - 

@article{
author = "Majstorović, Helena and Ratkov-Zebeljan, D and Tešić, Živoslav Lj. and Milojković-Opsenica, Dušanka",
year = "2004",
abstract = "The chromatographic behavior of some phenolic compounds has been studied with the objective of understanding the role of cyano groups in the processes of chromatographic separation on thin layers of CN-silica gel. For this purpose separations were performed on thin layers of CN-silica gel, unmodified silica gel, and polyacrylonitrile adsorbent (PANS) using fourteen mobile phases, nine of which resulted in normal-phase systems. On the basis of the results obtained the effect of compound structure (i.e. properties of ortho substituents of the compounds separated) on their retention is discussed. The dependence of the order of retention of the phenols on the properties of the adsorbent was also considered. Plots of retention data (R-M against R-M) determined by use of different chromatographic systems were used to characterize the systems used. The results enabled hypotheses to be formulated about possible mechanisms involved in the separations of the phenols on these adsorbents.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography",
title = "Interpretation of the mechanisms of chromatographic separation on CN-silica. Part II. TLC of some phenols",
volume = "17",
number = "1",
pages = "9-13",
doi = "10.1556/JPC.17.2004.1.2"
}

Majstorović, H., Ratkov-Zebeljan, D., Tešić, Ž. Lj.,& Milojković-Opsenica, D.. (2004). Interpretation of the mechanisms of chromatographic separation on CN-silica. Part II. TLC of some phenols. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
Research Inst Medicinal Plants, Budakalasz., 17(1), 9-13.
https://doi.org/10.1556/JPC.17.2004.1.2

Majstorović H, Ratkov-Zebeljan D, Tešić ŽL, Milojković-Opsenica D. Interpretation of the mechanisms of chromatographic separation on CN-silica. Part II. TLC of some phenols. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography. 2004;17(1):9-13.
doi:10.1556/JPC.17.2004.1.2 .

Majstorović, Helena, Ratkov-Zebeljan, D, Tešić, Živoslav Lj., Milojković-Opsenica, Dušanka, "Interpretation of the mechanisms of chromatographic separation on CN-silica. Part II. TLC of some phenols" in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography, 17, no. 1 (2004):9-13,
https://doi.org/10.1556/JPC.17.2004.1.2 . .

TY  - JOUR
AU  - Majstorović, Helena
AU  - Tešić, Živoslav Lj.
AU  - Milojković-Opsenica, Dušanka
PY  - 2002
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/519
AB  - The chromatographic behavior of four mixed tris(beta-diketonato) complexes of the type [Co(acac)(3-n)(phacphac)(n)] (n = 0-3), three (beta-ketoiminato)-Cu(II) complexes, two tris(alkylxanthato)-Co(III) complexes, and five bis(alkylxanthato)-Ni(II) complexes has been studied on thin layers of CN-silica gel with fifteen mobile phases, thirteen of which resulted in normal-phase systems. Linear relationships were established between the R, values of tris(beta-diketonato) complexes and the amount [% nu/nu] of acetone in hexane-acetone mobile phases, and between the R-M values of these complexes and the number of acac ligands substituted by phacphac ligands. The results obtained were compared with previously observed chromatographic behavior of the same substances on thin layers of silica gel and polyacrylonitrile. The corresponding separation mechanisms were also considered. It was assumed that under conditions of normal-phase chromatography with solvents of low polarity the retention behavior of complexes containing aromatic rings in the molecule is mainly determined by donor-acceptor interactions of the cyano groups of the adsorbent with the pi-electron systems of the substances being separated.
PB  - Research Inst Medicinal Plants, Budakalasz
T2  - Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
T1  - Interpretation of the mechanisms of chromatographic separation on CN-silica. Part I: TLC of metal complexes
VL  - 15
IS  - 5
SP  - 341
EP  - 344
DO  - 10.1556/JPC.15.2002.5.4
ER  - 

@article{
author = "Majstorović, Helena and Tešić, Živoslav Lj. and Milojković-Opsenica, Dušanka",
year = "2002",
abstract = "The chromatographic behavior of four mixed tris(beta-diketonato) complexes of the type [Co(acac)(3-n)(phacphac)(n)] (n = 0-3), three (beta-ketoiminato)-Cu(II) complexes, two tris(alkylxanthato)-Co(III) complexes, and five bis(alkylxanthato)-Ni(II) complexes has been studied on thin layers of CN-silica gel with fifteen mobile phases, thirteen of which resulted in normal-phase systems. Linear relationships were established between the R, values of tris(beta-diketonato) complexes and the amount [% nu/nu] of acetone in hexane-acetone mobile phases, and between the R-M values of these complexes and the number of acac ligands substituted by phacphac ligands. The results obtained were compared with previously observed chromatographic behavior of the same substances on thin layers of silica gel and polyacrylonitrile. The corresponding separation mechanisms were also considered. It was assumed that under conditions of normal-phase chromatography with solvents of low polarity the retention behavior of complexes containing aromatic rings in the molecule is mainly determined by donor-acceptor interactions of the cyano groups of the adsorbent with the pi-electron systems of the substances being separated.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography",
title = "Interpretation of the mechanisms of chromatographic separation on CN-silica. Part I: TLC of metal complexes",
volume = "15",
number = "5",
pages = "341-344",
doi = "10.1556/JPC.15.2002.5.4"
}

Majstorović, H., Tešić, Ž. Lj.,& Milojković-Opsenica, D.. (2002). Interpretation of the mechanisms of chromatographic separation on CN-silica. Part I: TLC of metal complexes. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
Research Inst Medicinal Plants, Budakalasz., 15(5), 341-344.
https://doi.org/10.1556/JPC.15.2002.5.4

Majstorović H, Tešić ŽL, Milojković-Opsenica D. Interpretation of the mechanisms of chromatographic separation on CN-silica. Part I: TLC of metal complexes. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography. 2002;15(5):341-344.
doi:10.1556/JPC.15.2002.5.4 .

Majstorović, Helena, Tešić, Živoslav Lj., Milojković-Opsenica, Dušanka, "Interpretation of the mechanisms of chromatographic separation on CN-silica. Part I: TLC of metal complexes" in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography, 15, no. 5 (2002):341-344,
https://doi.org/10.1556/JPC.15.2002.5.4 . .