Živković, Ljiljana S.

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orcid::0000-0003-2243-2835
  • Živković, Ljiljana S. (9)
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Author's Bibliography

Stable colloidal dispersions of fullerene C60, curcumin and C60-curcumin in water as potential antioxidants

Kop, Tatjana; Bjelaković, Mira S.; Živković, Ljiljana S.; Žekić, Andrijana; Milić, Dragana

(Elsevier, 2022)

TY  - JOUR
AU  - Kop, Tatjana
AU  - Bjelaković, Mira S.
AU  - Živković, Ljiljana S.
AU  - Žekić, Andrijana
AU  - Milić, Dragana
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5319
AB  - Despite many advantages, the practical application of fullerene C60 and curcumin (CUR) has been limited by their hydrophobic nature, deficient solubility in aqueous media and, therefore, poor bioavailability. In this study, aqueous nanoformulations containing C60 and CUR in the absence and presence of three solubility enhancers, β-cyclodextrin (CD), Tween 80 (T80) and polyvinylpyrrolidone (PVP), were prepared and subjected to the antioxidant activity assessment. The content of C60 and CUR, stability, size and morphology of nanoparticles were determined using UV–vis, DLS and SEM techniques. Contrary to better solubility of pure C60 than the corresponding C60-CUR system, the solubilization of CUR in hybrid suspensions was improved compared to corresponding pure CUR suspensions, with the exception of the C60-CUR-PVP formulation. The DLS results revealed nearly monodisperse nature of CUR-T80 nanoformulation, while other ones ranged from widely dispersed to polydispersed. Depending on the type of solubilizer, similarity was observed in the particle size distributions of T80- and PVP-coated nanoformulations as well as water and CD nanoformulations. The presence of T80 differently and significantly reduces the particle size in all three nanoformulations, while PVP slightly reduces CUR-based nanoparticles but increases the size of C60 nanoparticles. Zeta potential values, ranging from − 9 mV to − 34 mV, show variation in the starting stability of nanoparticles, from unstable or relatively stable three PVP formulations and C60-T80 to highly stable CUR-T80 and C60-water. Compared to water nanoformulations as a control, SEM images of dispersant-coated nanoparticles lost the visible morphology of active components, showing variation in their morphology depending on the type of dispersant and active component used. Nanoformulations containing CUR in PVP and T80 expressed a very good antioxidant potential in DPPH radical scavenging assay, much stronger than ascorbic acid. At the same time, a moderate to high antioxidant activity in β-carotene bleaching assay was reached in PVP and T80 nanoformulations containing C60, CUR, and their noncovalent hybrid, as well. Our studies have shown that T80 and PVP colloidal systems containing C60-CUR hybrid, but also their individual components, can be used as stable antioxidant nanoformulations with potential application in the field of food and pharmacology.
PB  - Elsevier
T2  - Colloids and Surfaces A: Physicochemical and Engineering Aspects
T1  - Stable colloidal dispersions of fullerene C60, curcumin and C60-curcumin in water as potential antioxidants
VL  - 648
DO  - 10.1016/j.colsurfa.2022.129379
ER  - 
@article{
author = "Kop, Tatjana and Bjelaković, Mira S. and Živković, Ljiljana S. and Žekić, Andrijana and Milić, Dragana",
year = "2022",
abstract = "Despite many advantages, the practical application of fullerene C60 and curcumin (CUR) has been limited by their hydrophobic nature, deficient solubility in aqueous media and, therefore, poor bioavailability. In this study, aqueous nanoformulations containing C60 and CUR in the absence and presence of three solubility enhancers, β-cyclodextrin (CD), Tween 80 (T80) and polyvinylpyrrolidone (PVP), were prepared and subjected to the antioxidant activity assessment. The content of C60 and CUR, stability, size and morphology of nanoparticles were determined using UV–vis, DLS and SEM techniques. Contrary to better solubility of pure C60 than the corresponding C60-CUR system, the solubilization of CUR in hybrid suspensions was improved compared to corresponding pure CUR suspensions, with the exception of the C60-CUR-PVP formulation. The DLS results revealed nearly monodisperse nature of CUR-T80 nanoformulation, while other ones ranged from widely dispersed to polydispersed. Depending on the type of solubilizer, similarity was observed in the particle size distributions of T80- and PVP-coated nanoformulations as well as water and CD nanoformulations. The presence of T80 differently and significantly reduces the particle size in all three nanoformulations, while PVP slightly reduces CUR-based nanoparticles but increases the size of C60 nanoparticles. Zeta potential values, ranging from − 9 mV to − 34 mV, show variation in the starting stability of nanoparticles, from unstable or relatively stable three PVP formulations and C60-T80 to highly stable CUR-T80 and C60-water. Compared to water nanoformulations as a control, SEM images of dispersant-coated nanoparticles lost the visible morphology of active components, showing variation in their morphology depending on the type of dispersant and active component used. Nanoformulations containing CUR in PVP and T80 expressed a very good antioxidant potential in DPPH radical scavenging assay, much stronger than ascorbic acid. At the same time, a moderate to high antioxidant activity in β-carotene bleaching assay was reached in PVP and T80 nanoformulations containing C60, CUR, and their noncovalent hybrid, as well. Our studies have shown that T80 and PVP colloidal systems containing C60-CUR hybrid, but also their individual components, can be used as stable antioxidant nanoformulations with potential application in the field of food and pharmacology.",
publisher = "Elsevier",
journal = "Colloids and Surfaces A: Physicochemical and Engineering Aspects",
title = "Stable colloidal dispersions of fullerene C60, curcumin and C60-curcumin in water as potential antioxidants",
volume = "648",
doi = "10.1016/j.colsurfa.2022.129379"
}
Kop, T., Bjelaković, M. S., Živković, L. S., Žekić, A.,& Milić, D.. (2022). Stable colloidal dispersions of fullerene C60, curcumin and C60-curcumin in water as potential antioxidants. in Colloids and Surfaces A: Physicochemical and Engineering Aspects
Elsevier., 648.
https://doi.org/10.1016/j.colsurfa.2022.129379
Kop T, Bjelaković MS, Živković LS, Žekić A, Milić D. Stable colloidal dispersions of fullerene C60, curcumin and C60-curcumin in water as potential antioxidants. in Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2022;648.
doi:10.1016/j.colsurfa.2022.129379 .
Kop, Tatjana, Bjelaković, Mira S., Živković, Ljiljana S., Žekić, Andrijana, Milić, Dragana, "Stable colloidal dispersions of fullerene C60, curcumin and C60-curcumin in water as potential antioxidants" in Colloids and Surfaces A: Physicochemical and Engineering Aspects, 648 (2022),
https://doi.org/10.1016/j.colsurfa.2022.129379 . .

Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity

Kop, Tatjana; Jakovljević, Dragica M.; Živković, Ljiljana S.; Žekić, Andrijana; Beškoski, Vladimir; Milić, Dragana; Gojgić-Cvijović, Gordana D.; Bjelaković, Mira S.

(Elsevier, 2020)

TY  - JOUR
AU  - Kop, Tatjana
AU  - Jakovljević, Dragica M.
AU  - Živković, Ljiljana S.
AU  - Žekić, Andrijana
AU  - Beškoski, Vladimir
AU  - Milić, Dragana
AU  - Gojgić-Cvijović, Gordana D.
AU  - Bjelaković, Mira S.
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3803
AB  - An efficient encapsulation of the fullerene into two hydrophobized and one native polysaccharide provided water soluble supramolecular hybrids. After covalent modification of polysaccharides by cholesterol, noncovalent hybrids were prepared by a three-step procedure, including mixing of individual aqueous solutions of hydrophobized, as well as native sugar with solution of the fullerene in pyridine, dialysis and lyophilization. Although the degree of the fullerene incorporation into hydrophobized substrates, cholesterol-levan and cholesterol-pullulan, was lower in comparison to the native polysaccharide levan, hydrophobization provided nanoparticles with improved properties. The particle size distribution, studied by dynamic light scattering and scanning electron microscopy revealed formation of moderately polydisperse aggregates, with the diameter contraction in comparison to the corresponding free polysaccharide, especially in the case of hydrophobized substrates. The morphological examination, done by scanning electron microscopy indicated the self-organization of the fullerene-native polysaccharide to round individual structures, while fullerene-hydrophobized polysaccharide hybrids tend to form networks. The antioxidant activity of the synthesized polysaccharide-C60 noncovalent hybrids versus starting polysaccharides was investigated by the DPPH radical scavenging and the β-carotene-linoleic acid bleaching methods. In all three complexes, the radical scavenging ability of the fullerene remained preserved, and a positive effect of levan hydrophobization was observed.
PB  - Elsevier
T2  - European Polymer Journal
T1  - Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity
VL  - 123
IS  - 109461
DO  - 10.1016/j.eurpolymj.2019.109461
ER  - 
@article{
author = "Kop, Tatjana and Jakovljević, Dragica M. and Živković, Ljiljana S. and Žekić, Andrijana and Beškoski, Vladimir and Milić, Dragana and Gojgić-Cvijović, Gordana D. and Bjelaković, Mira S.",
year = "2020",
abstract = "An efficient encapsulation of the fullerene into two hydrophobized and one native polysaccharide provided water soluble supramolecular hybrids. After covalent modification of polysaccharides by cholesterol, noncovalent hybrids were prepared by a three-step procedure, including mixing of individual aqueous solutions of hydrophobized, as well as native sugar with solution of the fullerene in pyridine, dialysis and lyophilization. Although the degree of the fullerene incorporation into hydrophobized substrates, cholesterol-levan and cholesterol-pullulan, was lower in comparison to the native polysaccharide levan, hydrophobization provided nanoparticles with improved properties. The particle size distribution, studied by dynamic light scattering and scanning electron microscopy revealed formation of moderately polydisperse aggregates, with the diameter contraction in comparison to the corresponding free polysaccharide, especially in the case of hydrophobized substrates. The morphological examination, done by scanning electron microscopy indicated the self-organization of the fullerene-native polysaccharide to round individual structures, while fullerene-hydrophobized polysaccharide hybrids tend to form networks. The antioxidant activity of the synthesized polysaccharide-C60 noncovalent hybrids versus starting polysaccharides was investigated by the DPPH radical scavenging and the β-carotene-linoleic acid bleaching methods. In all three complexes, the radical scavenging ability of the fullerene remained preserved, and a positive effect of levan hydrophobization was observed.",
publisher = "Elsevier",
journal = "European Polymer Journal",
title = "Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity",
volume = "123",
number = "109461",
doi = "10.1016/j.eurpolymj.2019.109461"
}
Kop, T., Jakovljević, D. M., Živković, L. S., Žekić, A., Beškoski, V., Milić, D., Gojgić-Cvijović, G. D.,& Bjelaković, M. S.. (2020). Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity. in European Polymer Journal
Elsevier., 123(109461).
https://doi.org/10.1016/j.eurpolymj.2019.109461
Kop T, Jakovljević DM, Živković LS, Žekić A, Beškoski V, Milić D, Gojgić-Cvijović GD, Bjelaković MS. Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity. in European Polymer Journal. 2020;123(109461).
doi:10.1016/j.eurpolymj.2019.109461 .
Kop, Tatjana, Jakovljević, Dragica M., Živković, Ljiljana S., Žekić, Andrijana, Beškoski, Vladimir, Milić, Dragana, Gojgić-Cvijović, Gordana D., Bjelaković, Mira S., "Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity" in European Polymer Journal, 123, no. 109461 (2020),
https://doi.org/10.1016/j.eurpolymj.2019.109461 . .
10
1
7

Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity

Kop, Tatjana; Jakovljević, Dragica M.; Živković, Ljiljana S.; Žekić, Andrijana; Beškoski, Vladimir; Milić, Dragana; Gojgić-Cvijović, Gordana D.; Bjelaković, Mira S.

(Elsevier, 2020)

TY  - JOUR
AU  - Kop, Tatjana
AU  - Jakovljević, Dragica M.
AU  - Živković, Ljiljana S.
AU  - Žekić, Andrijana
AU  - Beškoski, Vladimir
AU  - Milić, Dragana
AU  - Gojgić-Cvijović, Gordana D.
AU  - Bjelaković, Mira S.
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3830
AB  - An efficient encapsulation of the fullerene into two hydrophobized and one native polysaccharide provided water soluble supramolecular hybrids. After covalent modification of polysaccharides by cholesterol, noncovalent hybrids were prepared by a three-step procedure, including mixing of individual aqueous solutions of hydrophobized, as well as native sugar with solution of the fullerene in pyridine, dialysis and lyophilization. Although the degree of the fullerene incorporation into hydrophobized substrates, cholesterol-levan and cholesterol-pullulan, was lower in comparison to the native polysaccharide levan, hydrophobization provided nanoparticles with improved properties. The particle size distribution, studied by dynamic light scattering and scanning electron microscopy revealed formation of moderately polydisperse aggregates, with the diameter contraction in comparison to the corresponding free polysaccharide, especially in the case of hydrophobized substrates. The morphological examination, done by scanning electron microscopy indicated the self-organization of the fullerene-native polysaccharide to round individual structures, while fullerene-hydrophobized polysaccharide hybrids tend to form networks. The antioxidant activity of the synthesized polysaccharide-C60 noncovalent hybrids versus starting polysaccharides was investigated by the DPPH radical scavenging and the β-carotene-linoleic acid bleaching methods. In all three complexes, the radical scavenging ability of the fullerene remained preserved, and a positive effect of levan hydrophobization was observed.
PB  - Elsevier
T2  - European Polymer Journal
T1  - Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity
VL  - 123
SP  - 109461
DO  - 10.1016/j.eurpolymj.2019.109461
ER  - 
@article{
author = "Kop, Tatjana and Jakovljević, Dragica M. and Živković, Ljiljana S. and Žekić, Andrijana and Beškoski, Vladimir and Milić, Dragana and Gojgić-Cvijović, Gordana D. and Bjelaković, Mira S.",
year = "2020",
abstract = "An efficient encapsulation of the fullerene into two hydrophobized and one native polysaccharide provided water soluble supramolecular hybrids. After covalent modification of polysaccharides by cholesterol, noncovalent hybrids were prepared by a three-step procedure, including mixing of individual aqueous solutions of hydrophobized, as well as native sugar with solution of the fullerene in pyridine, dialysis and lyophilization. Although the degree of the fullerene incorporation into hydrophobized substrates, cholesterol-levan and cholesterol-pullulan, was lower in comparison to the native polysaccharide levan, hydrophobization provided nanoparticles with improved properties. The particle size distribution, studied by dynamic light scattering and scanning electron microscopy revealed formation of moderately polydisperse aggregates, with the diameter contraction in comparison to the corresponding free polysaccharide, especially in the case of hydrophobized substrates. The morphological examination, done by scanning electron microscopy indicated the self-organization of the fullerene-native polysaccharide to round individual structures, while fullerene-hydrophobized polysaccharide hybrids tend to form networks. The antioxidant activity of the synthesized polysaccharide-C60 noncovalent hybrids versus starting polysaccharides was investigated by the DPPH radical scavenging and the β-carotene-linoleic acid bleaching methods. In all three complexes, the radical scavenging ability of the fullerene remained preserved, and a positive effect of levan hydrophobization was observed.",
publisher = "Elsevier",
journal = "European Polymer Journal",
title = "Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity",
volume = "123",
pages = "109461",
doi = "10.1016/j.eurpolymj.2019.109461"
}
Kop, T., Jakovljević, D. M., Živković, L. S., Žekić, A., Beškoski, V., Milić, D., Gojgić-Cvijović, G. D.,& Bjelaković, M. S.. (2020). Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity. in European Polymer Journal
Elsevier., 123, 109461.
https://doi.org/10.1016/j.eurpolymj.2019.109461
Kop T, Jakovljević DM, Živković LS, Žekić A, Beškoski V, Milić D, Gojgić-Cvijović GD, Bjelaković MS. Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity. in European Polymer Journal. 2020;123:109461.
doi:10.1016/j.eurpolymj.2019.109461 .
Kop, Tatjana, Jakovljević, Dragica M., Živković, Ljiljana S., Žekić, Andrijana, Beškoski, Vladimir, Milić, Dragana, Gojgić-Cvijović, Gordana D., Bjelaković, Mira S., "Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity" in European Polymer Journal, 123 (2020):109461,
https://doi.org/10.1016/j.eurpolymj.2019.109461 . .
10
1
7

Cooperation of the pre-service chemistry and geography teachers on an interdisciplinary lesson planning

Trivić, Dragica; Džinović, Milanka; Milanović, Vesna D.; Živković, Ljiljana S.

(2019)

TY  - JOUR
AU  - Trivić, Dragica
AU  - Džinović, Milanka
AU  - Milanović, Vesna D.
AU  - Živković, Ljiljana S.
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3371
AB  - The aim of this research was to examine the effects of a new platform for raising the pre-service chemistry and geography teachers’ awareness of cooperation possibilities associated with the planning relevant interdisciplinary lesson. The research featured the participation of 16 students of the Faculty of Chemistry and 28 students of the Faculty of Geography of Belgrade University. Two workshops were conducted within the research. During the first workshop the participants worked in small groups on the tasks which served to strengthen their awareness on the relevant science education. The second workshop comprised the jointly planning the interdisciplinary lessons in groups with members of the pre-service teachers of both subjects. The participants’ lesson plans contain goals that can be classified as those relevant for the individual and those relevant for society. Half of the lesson plans contained formulations of goals that can be assessed as relevant for certain professions. The activities planned for the attainment of the stated goals support an interdisciplinary approach, encompass the concepts envisaged by the chemistry and geography curricula, and the activities specific to these two subjects.
T2  - Journal of Baltic Science Education
T1  - Cooperation of the pre-service chemistry and geography teachers on an interdisciplinary lesson planning
VL  - 18
IS  - 4
SP  - 620
EP  - 633
DO  - 10.33225/jbse/19.18.620
ER  - 
@article{
author = "Trivić, Dragica and Džinović, Milanka and Milanović, Vesna D. and Živković, Ljiljana S.",
year = "2019",
abstract = "The aim of this research was to examine the effects of a new platform for raising the pre-service chemistry and geography teachers’ awareness of cooperation possibilities associated with the planning relevant interdisciplinary lesson. The research featured the participation of 16 students of the Faculty of Chemistry and 28 students of the Faculty of Geography of Belgrade University. Two workshops were conducted within the research. During the first workshop the participants worked in small groups on the tasks which served to strengthen their awareness on the relevant science education. The second workshop comprised the jointly planning the interdisciplinary lessons in groups with members of the pre-service teachers of both subjects. The participants’ lesson plans contain goals that can be classified as those relevant for the individual and those relevant for society. Half of the lesson plans contained formulations of goals that can be assessed as relevant for certain professions. The activities planned for the attainment of the stated goals support an interdisciplinary approach, encompass the concepts envisaged by the chemistry and geography curricula, and the activities specific to these two subjects.",
journal = "Journal of Baltic Science Education",
title = "Cooperation of the pre-service chemistry and geography teachers on an interdisciplinary lesson planning",
volume = "18",
number = "4",
pages = "620-633",
doi = "10.33225/jbse/19.18.620"
}
Trivić, D., Džinović, M., Milanović, V. D.,& Živković, L. S.. (2019). Cooperation of the pre-service chemistry and geography teachers on an interdisciplinary lesson planning. in Journal of Baltic Science Education, 18(4), 620-633.
https://doi.org/10.33225/jbse/19.18.620
Trivić D, Džinović M, Milanović VD, Živković LS. Cooperation of the pre-service chemistry and geography teachers on an interdisciplinary lesson planning. in Journal of Baltic Science Education. 2019;18(4):620-633.
doi:10.33225/jbse/19.18.620 .
Trivić, Dragica, Džinović, Milanka, Milanović, Vesna D., Živković, Ljiljana S., "Cooperation of the pre-service chemistry and geography teachers on an interdisciplinary lesson planning" in Journal of Baltic Science Education, 18, no. 4 (2019):620-633,
https://doi.org/10.33225/jbse/19.18.620 . .
2

Supplementary material for the article: Milenković, I.; Radotić, K.; Matović, B.; Prekajski, M.; Živković, L.; Jakovljević, D.; Gojgić-Cvijović, G.; Beškoski, V. Improving Stability of Cerium Oxide Nanoparticles by Microbial Polysaccharides Coating. Journal of the Serbian Chemical Society 2018, 83 (6), 745–757. https://doi.org/10.2298/JSC171205031M

Milenković, Ivana; Radotić, Ksenija; Matović, Branko; Prekajski, Marija; Živković, Ljiljana S.; Jakovljević, Dragica M.; Gojgić-Cvijović, Gordana D.; Beškoski, Vladimir

(Serbian Chemical Soc, Belgrade, 2018)

TY  - DATA
AU  - Milenković, Ivana
AU  - Radotić, Ksenija
AU  - Matović, Branko
AU  - Prekajski, Marija
AU  - Živković, Ljiljana S.
AU  - Jakovljević, Dragica M.
AU  - Gojgić-Cvijović, Gordana D.
AU  - Beškoski, Vladimir
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3207
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Supplementary material for the article: Milenković, I.; Radotić, K.; Matović, B.; Prekajski, M.; Živković, L.; Jakovljević, D.; Gojgić-Cvijović, G.; Beškoski, V. Improving Stability of Cerium Oxide Nanoparticles by Microbial Polysaccharides Coating. Journal of the Serbian Chemical Society 2018, 83 (6), 745–757. https://doi.org/10.2298/JSC171205031M
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3207
ER  - 
@misc{
author = "Milenković, Ivana and Radotić, Ksenija and Matović, Branko and Prekajski, Marija and Živković, Ljiljana S. and Jakovljević, Dragica M. and Gojgić-Cvijović, Gordana D. and Beškoski, Vladimir",
year = "2018",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Supplementary material for the article: Milenković, I.; Radotić, K.; Matović, B.; Prekajski, M.; Živković, L.; Jakovljević, D.; Gojgić-Cvijović, G.; Beškoski, V. Improving Stability of Cerium Oxide Nanoparticles by Microbial Polysaccharides Coating. Journal of the Serbian Chemical Society 2018, 83 (6), 745–757. https://doi.org/10.2298/JSC171205031M",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3207"
}
Milenković, I., Radotić, K., Matović, B., Prekajski, M., Živković, L. S., Jakovljević, D. M., Gojgić-Cvijović, G. D.,& Beškoski, V.. (2018). Supplementary material for the article: Milenković, I.; Radotić, K.; Matović, B.; Prekajski, M.; Živković, L.; Jakovljević, D.; Gojgić-Cvijović, G.; Beškoski, V. Improving Stability of Cerium Oxide Nanoparticles by Microbial Polysaccharides Coating. Journal of the Serbian Chemical Society 2018, 83 (6), 745–757. https://doi.org/10.2298/JSC171205031M. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade..
https://hdl.handle.net/21.15107/rcub_cherry_3207
Milenković I, Radotić K, Matović B, Prekajski M, Živković LS, Jakovljević DM, Gojgić-Cvijović GD, Beškoski V. Supplementary material for the article: Milenković, I.; Radotić, K.; Matović, B.; Prekajski, M.; Živković, L.; Jakovljević, D.; Gojgić-Cvijović, G.; Beškoski, V. Improving Stability of Cerium Oxide Nanoparticles by Microbial Polysaccharides Coating. Journal of the Serbian Chemical Society 2018, 83 (6), 745–757. https://doi.org/10.2298/JSC171205031M. in Journal of the Serbian Chemical Society. 2018;.
https://hdl.handle.net/21.15107/rcub_cherry_3207 .
Milenković, Ivana, Radotić, Ksenija, Matović, Branko, Prekajski, Marija, Živković, Ljiljana S., Jakovljević, Dragica M., Gojgić-Cvijović, Gordana D., Beškoski, Vladimir, "Supplementary material for the article: Milenković, I.; Radotić, K.; Matović, B.; Prekajski, M.; Živković, L.; Jakovljević, D.; Gojgić-Cvijović, G.; Beškoski, V. Improving Stability of Cerium Oxide Nanoparticles by Microbial Polysaccharides Coating. Journal of the Serbian Chemical Society 2018, 83 (6), 745–757. https://doi.org/10.2298/JSC171205031M" in Journal of the Serbian Chemical Society (2018),
https://hdl.handle.net/21.15107/rcub_cherry_3207 .

Improving stability of cerium oxide nanoparticles by microbial polysaccharides coating

Milenković, Ivana; Radotić, Ksenija; Matović, Branko; Prekajski, Marija; Živković, Ljiljana S.; Jakovljević, Dragica M.; Gojgić-Cvijović, Gordana D.; Beškoski, Vladimir

(Serbian Chemical Soc, Belgrade, 2018)

TY  - JOUR
AU  - Milenković, Ivana
AU  - Radotić, Ksenija
AU  - Matović, Branko
AU  - Prekajski, Marija
AU  - Živković, Ljiljana S.
AU  - Jakovljević, Dragica M.
AU  - Gojgić-Cvijović, Gordana D.
AU  - Beškoski, Vladimir
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2087
AB  - Cerium oxide (CeO2) nanoparticles (CONPs) are interesting biomaterials with various applications in biomedicine, cosmetics and the pharmaceutical industry, but with limited practical application because of their low stability in aqueous media. The aim of this study was to obtain CONPs with increased stability by coating the particles. Microbial exopolysaccharides (levan, pullulan) and glucose were used to prepare CONPs under different synthesis conditions. Coating was attempted by adding the carbohydrates during (direct coating) or after (subsequent coating) the synthesis of CONPs. The obtained nanoparticles were characterized by X-Ray diffraction analysis, Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The suspension stability of the uncoated and coated CONPs in aqueous media was evaluated by measuring the hydrodynamic size, zeta potential and turbidity. The FT-IR spectra revealed the differences between coated CONPs and showed the success of subsequent coating with carbohydrates. Coating with carbohydrates improved the stability the CONP suspension by decreasing the size of aggregated particles. The suspensions of levan- and glucose-coated CONPs had the best stability. In this study, CONPs were prepared using non-toxic materials, which were completely environmentally friendly. The obtained results open new horizons for CONP synthesis, improving their biological applications.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Improving stability of cerium oxide nanoparticles by microbial polysaccharides coating
VL  - 83
IS  - 6
SP  - 745
EP  - 757
DO  - 10.2298/JSC171205031M
UR  - Kon_3418
ER  - 
@article{
author = "Milenković, Ivana and Radotić, Ksenija and Matović, Branko and Prekajski, Marija and Živković, Ljiljana S. and Jakovljević, Dragica M. and Gojgić-Cvijović, Gordana D. and Beškoski, Vladimir",
year = "2018",
abstract = "Cerium oxide (CeO2) nanoparticles (CONPs) are interesting biomaterials with various applications in biomedicine, cosmetics and the pharmaceutical industry, but with limited practical application because of their low stability in aqueous media. The aim of this study was to obtain CONPs with increased stability by coating the particles. Microbial exopolysaccharides (levan, pullulan) and glucose were used to prepare CONPs under different synthesis conditions. Coating was attempted by adding the carbohydrates during (direct coating) or after (subsequent coating) the synthesis of CONPs. The obtained nanoparticles were characterized by X-Ray diffraction analysis, Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The suspension stability of the uncoated and coated CONPs in aqueous media was evaluated by measuring the hydrodynamic size, zeta potential and turbidity. The FT-IR spectra revealed the differences between coated CONPs and showed the success of subsequent coating with carbohydrates. Coating with carbohydrates improved the stability the CONP suspension by decreasing the size of aggregated particles. The suspensions of levan- and glucose-coated CONPs had the best stability. In this study, CONPs were prepared using non-toxic materials, which were completely environmentally friendly. The obtained results open new horizons for CONP synthesis, improving their biological applications.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Improving stability of cerium oxide nanoparticles by microbial polysaccharides coating",
volume = "83",
number = "6",
pages = "745-757",
doi = "10.2298/JSC171205031M",
url = "Kon_3418"
}
Milenković, I., Radotić, K., Matović, B., Prekajski, M., Živković, L. S., Jakovljević, D. M., Gojgić-Cvijović, G. D.,& Beškoski, V.. (2018). Improving stability of cerium oxide nanoparticles by microbial polysaccharides coating. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 83(6), 745-757.
https://doi.org/10.2298/JSC171205031M
Kon_3418
Milenković I, Radotić K, Matović B, Prekajski M, Živković LS, Jakovljević DM, Gojgić-Cvijović GD, Beškoski V. Improving stability of cerium oxide nanoparticles by microbial polysaccharides coating. in Journal of the Serbian Chemical Society. 2018;83(6):745-757.
doi:10.2298/JSC171205031M
Kon_3418 .
Milenković, Ivana, Radotić, Ksenija, Matović, Branko, Prekajski, Marija, Živković, Ljiljana S., Jakovljević, Dragica M., Gojgić-Cvijović, Gordana D., Beškoski, Vladimir, "Improving stability of cerium oxide nanoparticles by microbial polysaccharides coating" in Journal of the Serbian Chemical Society, 83, no. 6 (2018):745-757,
https://doi.org/10.2298/JSC171205031M .,
Kon_3418 .
10
9
9

Supplementary data for the article: Izrael Živković, L. T.; Živković, L. S.; Beškoski, V. P.; Gopčević, K. R.; Jokić, B. M.; Radosavljević, D. S.; Karadžić, I. M. The Candida Rugosa Lipase Adsorbed onto Titania as Nano Biocatalyst with Improved Thermostability and Reuse Potential in Aqueous and Organic Media. Journal of Molecular Catalysis B: Enzymatic 2016, 133, S533–S542. https://doi.org/10.1016/j.molcatb.2017.06.001

Izrael-Živković, Lidija; Živković, Ljiljana S.; Beškoski, Vladimir; Gopčević, Kristina; Jokić, Bojan; Radosavljević, Dragoslav S.; Karadžić, Ivanka M.

(2016)

TY  - DATA
AU  - Izrael-Živković, Lidija
AU  - Živković, Ljiljana S.
AU  - Beškoski, Vladimir
AU  - Gopčević, Kristina
AU  - Jokić, Bojan
AU  - Radosavljević, Dragoslav S.
AU  - Karadžić, Ivanka M.
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3649
T2  - Journal of Molecular Catalysis. B: Enzymatic
T1  - Supplementary data for the article: Izrael Živković, L. T.; Živković, L. S.; Beškoski, V. P.; Gopčević, K. R.; Jokić, B. M.; Radosavljević, D. S.; Karadžić, I. M. The Candida Rugosa Lipase Adsorbed onto Titania as Nano Biocatalyst with Improved Thermostability and Reuse Potential in Aqueous and Organic Media. Journal of Molecular Catalysis B: Enzymatic 2016, 133, S533–S542. https://doi.org/10.1016/j.molcatb.2017.06.001
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3649
ER  - 
@misc{
author = "Izrael-Živković, Lidija and Živković, Ljiljana S. and Beškoski, Vladimir and Gopčević, Kristina and Jokić, Bojan and Radosavljević, Dragoslav S. and Karadžić, Ivanka M.",
year = "2016",
journal = "Journal of Molecular Catalysis. B: Enzymatic",
title = "Supplementary data for the article: Izrael Živković, L. T.; Živković, L. S.; Beškoski, V. P.; Gopčević, K. R.; Jokić, B. M.; Radosavljević, D. S.; Karadžić, I. M. The Candida Rugosa Lipase Adsorbed onto Titania as Nano Biocatalyst with Improved Thermostability and Reuse Potential in Aqueous and Organic Media. Journal of Molecular Catalysis B: Enzymatic 2016, 133, S533–S542. https://doi.org/10.1016/j.molcatb.2017.06.001",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3649"
}
Izrael-Živković, L., Živković, L. S., Beškoski, V., Gopčević, K., Jokić, B., Radosavljević, D. S.,& Karadžić, I. M.. (2016). Supplementary data for the article: Izrael Živković, L. T.; Živković, L. S.; Beškoski, V. P.; Gopčević, K. R.; Jokić, B. M.; Radosavljević, D. S.; Karadžić, I. M. The Candida Rugosa Lipase Adsorbed onto Titania as Nano Biocatalyst with Improved Thermostability and Reuse Potential in Aqueous and Organic Media. Journal of Molecular Catalysis B: Enzymatic 2016, 133, S533–S542. https://doi.org/10.1016/j.molcatb.2017.06.001. in Journal of Molecular Catalysis. B: Enzymatic.
https://hdl.handle.net/21.15107/rcub_cherry_3649
Izrael-Živković L, Živković LS, Beškoski V, Gopčević K, Jokić B, Radosavljević DS, Karadžić IM. Supplementary data for the article: Izrael Živković, L. T.; Živković, L. S.; Beškoski, V. P.; Gopčević, K. R.; Jokić, B. M.; Radosavljević, D. S.; Karadžić, I. M. The Candida Rugosa Lipase Adsorbed onto Titania as Nano Biocatalyst with Improved Thermostability and Reuse Potential in Aqueous and Organic Media. Journal of Molecular Catalysis B: Enzymatic 2016, 133, S533–S542. https://doi.org/10.1016/j.molcatb.2017.06.001. in Journal of Molecular Catalysis. B: Enzymatic. 2016;.
https://hdl.handle.net/21.15107/rcub_cherry_3649 .
Izrael-Živković, Lidija, Živković, Ljiljana S., Beškoski, Vladimir, Gopčević, Kristina, Jokić, Bojan, Radosavljević, Dragoslav S., Karadžić, Ivanka M., "Supplementary data for the article: Izrael Živković, L. T.; Živković, L. S.; Beškoski, V. P.; Gopčević, K. R.; Jokić, B. M.; Radosavljević, D. S.; Karadžić, I. M. The Candida Rugosa Lipase Adsorbed onto Titania as Nano Biocatalyst with Improved Thermostability and Reuse Potential in Aqueous and Organic Media. Journal of Molecular Catalysis B: Enzymatic 2016, 133, S533–S542. https://doi.org/10.1016/j.molcatb.2017.06.001" in Journal of Molecular Catalysis. B: Enzymatic (2016),
https://hdl.handle.net/21.15107/rcub_cherry_3649 .

The Candida rugosa lipase adsorbed onto titania as nano biocatalyst with improved thermostability and reuse potential in aqueous and organic media

Izrael-Živković, Lidija; Živković, Ljiljana S.; Beškoski, Vladimir; Gopčević, Kristina; Jokić, Bojan; Radosavljević, Dragoslav S.; Karadžić, Ivanka M.

(2016)

TY  - JOUR
AU  - Izrael-Živković, Lidija
AU  - Živković, Ljiljana S.
AU  - Beškoski, Vladimir
AU  - Gopčević, Kristina
AU  - Jokić, Bojan
AU  - Radosavljević, Dragoslav S.
AU  - Karadžić, Ivanka M.
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3648
AB  - The immobilization of Candida rugosa lipase by adsorption was performed onto commercial titania powder (Degussa P25). The change of titania particles surface was diagnosed by means of FTIR and FESEM analysis, as well as by shift of zeta potential value towards that of lipase. A detailed study of the effect of immobilization on enzyme kinetic, temperature stability, as well as on potential for its reuse in aqueous organic media was undertaken. Immobilization of lipase altered enzyme affinity toward substrates with different length of carbon chain in hydrolytic reaction. The Vmax value decreased 2–8-fold, where major constraint was registered for the ester containing the longest carbon chain. Thermostability of lipase improved more than 7-fold at 60 °C. Significant potential for reuse in water solutions was also found after immobilization. In cyclohexane immobilized lipase catalyzed synthesis of amyl octanoate by ping-pong bi–bi mechanism with inhibition by amyl alcohol. Obtained kinetic constants were Vmax = 26.4 μmol min−1, KAc = 0.52 mol/L, KAl = 0.2 mol/L and Ki,Al = 0.644 mol/L. Esterification activity remained 60% after 5 reuse cycles in cyclohexane indicating moderate reuse stability. © 2017 Elsevier B.V.
T2  - Journal of Molecular Catalysis. B: Enzymatic
T1  - The Candida rugosa lipase adsorbed onto titania as nano biocatalyst with improved thermostability and reuse potential in aqueous and organic media
VL  - 133
DO  - 10.1016/j.molcatb.2017.06.001
UR  - Kon_1282
ER  - 
@article{
author = "Izrael-Živković, Lidija and Živković, Ljiljana S. and Beškoski, Vladimir and Gopčević, Kristina and Jokić, Bojan and Radosavljević, Dragoslav S. and Karadžić, Ivanka M.",
year = "2016",
abstract = "The immobilization of Candida rugosa lipase by adsorption was performed onto commercial titania powder (Degussa P25). The change of titania particles surface was diagnosed by means of FTIR and FESEM analysis, as well as by shift of zeta potential value towards that of lipase. A detailed study of the effect of immobilization on enzyme kinetic, temperature stability, as well as on potential for its reuse in aqueous organic media was undertaken. Immobilization of lipase altered enzyme affinity toward substrates with different length of carbon chain in hydrolytic reaction. The Vmax value decreased 2–8-fold, where major constraint was registered for the ester containing the longest carbon chain. Thermostability of lipase improved more than 7-fold at 60 °C. Significant potential for reuse in water solutions was also found after immobilization. In cyclohexane immobilized lipase catalyzed synthesis of amyl octanoate by ping-pong bi–bi mechanism with inhibition by amyl alcohol. Obtained kinetic constants were Vmax = 26.4 μmol min−1, KAc = 0.52 mol/L, KAl = 0.2 mol/L and Ki,Al = 0.644 mol/L. Esterification activity remained 60% after 5 reuse cycles in cyclohexane indicating moderate reuse stability. © 2017 Elsevier B.V.",
journal = "Journal of Molecular Catalysis. B: Enzymatic",
title = "The Candida rugosa lipase adsorbed onto titania as nano biocatalyst with improved thermostability and reuse potential in aqueous and organic media",
volume = "133",
doi = "10.1016/j.molcatb.2017.06.001",
url = "Kon_1282"
}
Izrael-Živković, L., Živković, L. S., Beškoski, V., Gopčević, K., Jokić, B., Radosavljević, D. S.,& Karadžić, I. M.. (2016). The Candida rugosa lipase adsorbed onto titania as nano biocatalyst with improved thermostability and reuse potential in aqueous and organic media. in Journal of Molecular Catalysis. B: Enzymatic, 133.
https://doi.org/10.1016/j.molcatb.2017.06.001
Kon_1282
Izrael-Živković L, Živković LS, Beškoski V, Gopčević K, Jokić B, Radosavljević DS, Karadžić IM. The Candida rugosa lipase adsorbed onto titania as nano biocatalyst with improved thermostability and reuse potential in aqueous and organic media. in Journal of Molecular Catalysis. B: Enzymatic. 2016;133.
doi:10.1016/j.molcatb.2017.06.001
Kon_1282 .
Izrael-Živković, Lidija, Živković, Ljiljana S., Beškoski, Vladimir, Gopčević, Kristina, Jokić, Bojan, Radosavljević, Dragoslav S., Karadžić, Ivanka M., "The Candida rugosa lipase adsorbed onto titania as nano biocatalyst with improved thermostability and reuse potential in aqueous and organic media" in Journal of Molecular Catalysis. B: Enzymatic, 133 (2016),
https://doi.org/10.1016/j.molcatb.2017.06.001 .,
Kon_1282 .
6
5

The Candida rugosa lipase adsorbed onto titania as nano biocatalyst with improved thermostability and reuse potential in aqueous and organic media

Izrael-Živković, Lidija; Živković, Ljiljana S.; Beškoski, Vladimir; Gopčević, Kristina; Jokić, Bojan; Radosavljević, Dragoslav S.; Karadžić, Ivanka M.

(2016)

TY  - JOUR
AU  - Izrael-Živković, Lidija
AU  - Živković, Ljiljana S.
AU  - Beškoski, Vladimir
AU  - Gopčević, Kristina
AU  - Jokić, Bojan
AU  - Radosavljević, Dragoslav S.
AU  - Karadžić, Ivanka M.
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/315
AB  - The immobilization of Candida rugosa lipase by adsorption was performed onto commercial titania powder (Degussa P25). The change of titania particles surface was diagnosed by means of FTIR and FESEM analysis, as well as by shift of zeta potential value towards that of lipase. A detailed study of the effect of immobilization on enzyme kinetic, temperature stability, as well as on potential for its reuse in aqueous organic media was undertaken. Immobilization of lipase altered enzyme affinity toward substrates with different length of carbon chain in hydrolytic reaction. The Vmax value decreased 2–8-fold, where major constraint was registered for the ester containing the longest carbon chain. Thermostability of lipase improved more than 7-fold at 60 °C. Significant potential for reuse in water solutions was also found after immobilization. In cyclohexane immobilized lipase catalyzed synthesis of amyl octanoate by ping-pong bi–bi mechanism with inhibition by amyl alcohol. Obtained kinetic constants were Vmax = 26.4 μmol min−1, KAc = 0.52 mol/L, KAl = 0.2 mol/L and Ki,Al = 0.644 mol/L. Esterification activity remained 60% after 5 reuse cycles in cyclohexane indicating moderate reuse stability. © 2017 Elsevier B.V.
T2  - Journal of Molecular Catalysis. B: Enzymatic
T1  - The Candida rugosa lipase adsorbed onto titania as nano biocatalyst with improved thermostability and reuse potential in aqueous and organic media
VL  - 133
DO  - 10.1016/j.molcatb.2017.06.001
UR  - Kon_1282
ER  - 
@article{
author = "Izrael-Živković, Lidija and Živković, Ljiljana S. and Beškoski, Vladimir and Gopčević, Kristina and Jokić, Bojan and Radosavljević, Dragoslav S. and Karadžić, Ivanka M.",
year = "2016",
abstract = "The immobilization of Candida rugosa lipase by adsorption was performed onto commercial titania powder (Degussa P25). The change of titania particles surface was diagnosed by means of FTIR and FESEM analysis, as well as by shift of zeta potential value towards that of lipase. A detailed study of the effect of immobilization on enzyme kinetic, temperature stability, as well as on potential for its reuse in aqueous organic media was undertaken. Immobilization of lipase altered enzyme affinity toward substrates with different length of carbon chain in hydrolytic reaction. The Vmax value decreased 2–8-fold, where major constraint was registered for the ester containing the longest carbon chain. Thermostability of lipase improved more than 7-fold at 60 °C. Significant potential for reuse in water solutions was also found after immobilization. In cyclohexane immobilized lipase catalyzed synthesis of amyl octanoate by ping-pong bi–bi mechanism with inhibition by amyl alcohol. Obtained kinetic constants were Vmax = 26.4 μmol min−1, KAc = 0.52 mol/L, KAl = 0.2 mol/L and Ki,Al = 0.644 mol/L. Esterification activity remained 60% after 5 reuse cycles in cyclohexane indicating moderate reuse stability. © 2017 Elsevier B.V.",
journal = "Journal of Molecular Catalysis. B: Enzymatic",
title = "The Candida rugosa lipase adsorbed onto titania as nano biocatalyst with improved thermostability and reuse potential in aqueous and organic media",
volume = "133",
doi = "10.1016/j.molcatb.2017.06.001",
url = "Kon_1282"
}
Izrael-Živković, L., Živković, L. S., Beškoski, V., Gopčević, K., Jokić, B., Radosavljević, D. S.,& Karadžić, I. M.. (2016). The Candida rugosa lipase adsorbed onto titania as nano biocatalyst with improved thermostability and reuse potential in aqueous and organic media. in Journal of Molecular Catalysis. B: Enzymatic, 133.
https://doi.org/10.1016/j.molcatb.2017.06.001
Kon_1282
Izrael-Živković L, Živković LS, Beškoski V, Gopčević K, Jokić B, Radosavljević DS, Karadžić IM. The Candida rugosa lipase adsorbed onto titania as nano biocatalyst with improved thermostability and reuse potential in aqueous and organic media. in Journal of Molecular Catalysis. B: Enzymatic. 2016;133.
doi:10.1016/j.molcatb.2017.06.001
Kon_1282 .
Izrael-Živković, Lidija, Živković, Ljiljana S., Beškoski, Vladimir, Gopčević, Kristina, Jokić, Bojan, Radosavljević, Dragoslav S., Karadžić, Ivanka M., "The Candida rugosa lipase adsorbed onto titania as nano biocatalyst with improved thermostability and reuse potential in aqueous and organic media" in Journal of Molecular Catalysis. B: Enzymatic, 133 (2016),
https://doi.org/10.1016/j.molcatb.2017.06.001 .,
Kon_1282 .
6
5