Ivković, Đurđa

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  • Ivković, Đurđa (10)

Author's Bibliography

Enhancement of propolis food preservation and functional ingredient characteristics by natural eutectic solvents extraction of phytochemicals

Lazović, Mila; Ivković, Đurđa; Jankov, Milica; Dimkić, Ivica; Janakiev, Tamara; Trifković, Jelena; Milojković-Opsenica, Dušanka; Ristivojević, Petar

(Elsevier, 2024)

TY  - JOUR
AU  - Lazović, Mila
AU  - Ivković, Đurđa
AU  - Jankov, Milica
AU  - Dimkić, Ivica
AU  - Janakiev, Tamara
AU  - Trifković, Jelena
AU  - Milojković-Opsenica, Dušanka
AU  - Ristivojević, Petar
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6444
AB  - Due to the promising applications of propolis as a natural food preservative, functional ingredient or supplement, on one side, and the inherent toxicity and high volatility of organic solvents used for extraction of phenolics from propolis, a range of natural eutectic solvents (NESs) was evaluated for the extraction of phenolic compounds from poplar type propolis to create “green-labelled” food products. The phenolic profile of novel green propolis extracts was evaluated using high-performance thin-layer chromatography, while 16 phenolic compounds were quantified by ultra-high-performance liquid chromatography hyphenated with mass spectrometry. Pinocembrin and chrysin were the most dominant phenolics with an average concentration of 3111 and 3039 mg/kg in lactic acid-based NES, respectively. Biological activity, such as antioxidative and antimicrobial activities, were determined using spectrophotometric and well diffusion methods. Considering all spectrophotometric assays lactic acid-based presented as the best extraction medium for phenolic extraction, with TPC, TFC and RSA values 150.0 mg GAE/g, 190.0 mg RUE/g, and 132.8 mg TE/g on average, respectively. From 38 studied NESs, choline-chloride:tartaric acid (1:1 n/n), glycerol:lactic acid (1:1 n/n) and glycine: lactic acid (1:3 n/n) were the most promising extraction medium for obtaining the propolis extracts enriched with bioactive compounds. Additionally, proposed green solvents were proved to be the designer solvents and showed potential to be tuned to target specific phenolic compounds. Improved, or at least maintained, biological activity of NES propolis extracts support its application in agriculture industry.
PB  - Elsevier
T2  - Food Bioscience
T1  - Enhancement of propolis food preservation and functional ingredient characteristics by natural eutectic solvents extraction of phytochemicals
VL  - 57
SP  - 103467
DO  - 10.1016/j.fbio.2023.103467
ER  - 
@article{
author = "Lazović, Mila and Ivković, Đurđa and Jankov, Milica and Dimkić, Ivica and Janakiev, Tamara and Trifković, Jelena and Milojković-Opsenica, Dušanka and Ristivojević, Petar",
year = "2024",
abstract = "Due to the promising applications of propolis as a natural food preservative, functional ingredient or supplement, on one side, and the inherent toxicity and high volatility of organic solvents used for extraction of phenolics from propolis, a range of natural eutectic solvents (NESs) was evaluated for the extraction of phenolic compounds from poplar type propolis to create “green-labelled” food products. The phenolic profile of novel green propolis extracts was evaluated using high-performance thin-layer chromatography, while 16 phenolic compounds were quantified by ultra-high-performance liquid chromatography hyphenated with mass spectrometry. Pinocembrin and chrysin were the most dominant phenolics with an average concentration of 3111 and 3039 mg/kg in lactic acid-based NES, respectively. Biological activity, such as antioxidative and antimicrobial activities, were determined using spectrophotometric and well diffusion methods. Considering all spectrophotometric assays lactic acid-based presented as the best extraction medium for phenolic extraction, with TPC, TFC and RSA values 150.0 mg GAE/g, 190.0 mg RUE/g, and 132.8 mg TE/g on average, respectively. From 38 studied NESs, choline-chloride:tartaric acid (1:1 n/n), glycerol:lactic acid (1:1 n/n) and glycine: lactic acid (1:3 n/n) were the most promising extraction medium for obtaining the propolis extracts enriched with bioactive compounds. Additionally, proposed green solvents were proved to be the designer solvents and showed potential to be tuned to target specific phenolic compounds. Improved, or at least maintained, biological activity of NES propolis extracts support its application in agriculture industry.",
publisher = "Elsevier",
journal = "Food Bioscience",
title = "Enhancement of propolis food preservation and functional ingredient characteristics by natural eutectic solvents extraction of phytochemicals",
volume = "57",
pages = "103467",
doi = "10.1016/j.fbio.2023.103467"
}
Lazović, M., Ivković, Đ., Jankov, M., Dimkić, I., Janakiev, T., Trifković, J., Milojković-Opsenica, D.,& Ristivojević, P.. (2024). Enhancement of propolis food preservation and functional ingredient characteristics by natural eutectic solvents extraction of phytochemicals. in Food Bioscience
Elsevier., 57, 103467.
https://doi.org/10.1016/j.fbio.2023.103467
Lazović M, Ivković Đ, Jankov M, Dimkić I, Janakiev T, Trifković J, Milojković-Opsenica D, Ristivojević P. Enhancement of propolis food preservation and functional ingredient characteristics by natural eutectic solvents extraction of phytochemicals. in Food Bioscience. 2024;57:103467.
doi:10.1016/j.fbio.2023.103467 .
Lazović, Mila, Ivković, Đurđa, Jankov, Milica, Dimkić, Ivica, Janakiev, Tamara, Trifković, Jelena, Milojković-Opsenica, Dušanka, Ristivojević, Petar, "Enhancement of propolis food preservation and functional ingredient characteristics by natural eutectic solvents extraction of phytochemicals" in Food Bioscience, 57 (2024):103467,
https://doi.org/10.1016/j.fbio.2023.103467 . .

Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening

Milutinović, Milica; Nakarada, Đura; Božunović, Jelena; Todorović, Miloš; Gašić, Uroš M.; Živković, Suzana; Skorić, Marijana; Ivković, Đurđa; Savić, Jelena; Devrnja, Nina; Aničić, Neda; Banjanac, Tijana; Mojović, Miloš; Mišić, Danijela

(MDPI, 2023)

TY  - JOUR
AU  - Milutinović, Milica
AU  - Nakarada, Đura
AU  - Božunović, Jelena
AU  - Todorović, Miloš
AU  - Gašić, Uroš M.
AU  - Živković, Suzana
AU  - Skorić, Marijana
AU  - Ivković, Đurđa
AU  - Savić, Jelena
AU  - Devrnja, Nina
AU  - Aničić, Neda
AU  - Banjanac, Tijana
AU  - Mojović, Miloš
AU  - Mišić, Danijela
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5896
AB  - The present study provides, for the first time, a physicochemical and biochemical characterization of the redox processes associated with the ripening of Solanum dulcamara L. (bittersweet) berries. Electron Paramagnetic Resonance Spectroscopy (EPRS) and Imaging (EPRI) measurements of reactive oxygen species (ROS) were performed in parallel with the tissue-specific metabolic profiling of major antioxidants and assessment of antioxidant enzymes activity. Fruit transition from the mature green (MG) to ripe red (RR) stage involved changes in the qualitative and quantitative content of antioxidants and the associated cellular oxidation and peroxidation processes. The skin of bittersweet berries, which was the major source of antioxidants, exhibited the highest antioxidant potential against DPPH radicals and nitroxyl spin probe 3CP. The efficient enzymatic antioxidant system played a critical protective role against the deleterious effects of progressive oxidative stress during ripening. Here, we present the EPRI methodology to assess the redox status of fruits and to discriminate between the redox states of different tissues. Interestingly, the intracellular reoxidation of cell-permeable nitroxide probe 3CP was observed for the first time in fruits or any other plant tissue, and its intensity is herein proposed as a reliable indicator of oxidative stress during ripening. The described noninvasive EPRI technique has the potential to have broader application in the study of redox processes associated with the development, senescence, and postharvest storage of fruits, as well as other circumstances in which oxidative stress is implicated.
PB  - MDPI
T2  - Antioxidants
T2  - Antioxidants
T1  - Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening
VL  - 12
IS  - 2
SP  - 346
DO  - 10.3390/antiox12020346
ER  - 
@article{
author = "Milutinović, Milica and Nakarada, Đura and Božunović, Jelena and Todorović, Miloš and Gašić, Uroš M. and Živković, Suzana and Skorić, Marijana and Ivković, Đurđa and Savić, Jelena and Devrnja, Nina and Aničić, Neda and Banjanac, Tijana and Mojović, Miloš and Mišić, Danijela",
year = "2023",
abstract = "The present study provides, for the first time, a physicochemical and biochemical characterization of the redox processes associated with the ripening of Solanum dulcamara L. (bittersweet) berries. Electron Paramagnetic Resonance Spectroscopy (EPRS) and Imaging (EPRI) measurements of reactive oxygen species (ROS) were performed in parallel with the tissue-specific metabolic profiling of major antioxidants and assessment of antioxidant enzymes activity. Fruit transition from the mature green (MG) to ripe red (RR) stage involved changes in the qualitative and quantitative content of antioxidants and the associated cellular oxidation and peroxidation processes. The skin of bittersweet berries, which was the major source of antioxidants, exhibited the highest antioxidant potential against DPPH radicals and nitroxyl spin probe 3CP. The efficient enzymatic antioxidant system played a critical protective role against the deleterious effects of progressive oxidative stress during ripening. Here, we present the EPRI methodology to assess the redox status of fruits and to discriminate between the redox states of different tissues. Interestingly, the intracellular reoxidation of cell-permeable nitroxide probe 3CP was observed for the first time in fruits or any other plant tissue, and its intensity is herein proposed as a reliable indicator of oxidative stress during ripening. The described noninvasive EPRI technique has the potential to have broader application in the study of redox processes associated with the development, senescence, and postharvest storage of fruits, as well as other circumstances in which oxidative stress is implicated.",
publisher = "MDPI",
journal = "Antioxidants, Antioxidants",
title = "Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening",
volume = "12",
number = "2",
pages = "346",
doi = "10.3390/antiox12020346"
}
Milutinović, M., Nakarada, Đ., Božunović, J., Todorović, M., Gašić, U. M., Živković, S., Skorić, M., Ivković, Đ., Savić, J., Devrnja, N., Aničić, N., Banjanac, T., Mojović, M.,& Mišić, D.. (2023). Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening. in Antioxidants
MDPI., 12(2), 346.
https://doi.org/10.3390/antiox12020346
Milutinović M, Nakarada Đ, Božunović J, Todorović M, Gašić UM, Živković S, Skorić M, Ivković Đ, Savić J, Devrnja N, Aničić N, Banjanac T, Mojović M, Mišić D. Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening. in Antioxidants. 2023;12(2):346.
doi:10.3390/antiox12020346 .
Milutinović, Milica, Nakarada, Đura, Božunović, Jelena, Todorović, Miloš, Gašić, Uroš M., Živković, Suzana, Skorić, Marijana, Ivković, Đurđa, Savić, Jelena, Devrnja, Nina, Aničić, Neda, Banjanac, Tijana, Mojović, Miloš, Mišić, Danijela, "Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening" in Antioxidants, 12, no. 2 (2023):346,
https://doi.org/10.3390/antiox12020346 . .
4
4
1
1

Screening natural deep eutectic solvents (NaDES) using COSMO-RS for sustainable and environmentally-friendly cosmetic ingredients

Cvijetić, Ilija; Ivković, Đurđa; Todorović, Petar; Andrić, Filip; Ristivojević, Petar

(2023)

TY  - CONF
AU  - Cvijetić, Ilija
AU  - Ivković, Đurđa
AU  - Todorović, Petar
AU  - Andrić, Filip
AU  - Ristivojević, Petar
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6222
AB  - DES are mixtures of a hydrogen bond donor (HBD) and a hydrogen bond acceptor (HBA) that, when combined in a specific molar ratio, exhibit a significant decrease in melting point and become liquid at room temperature. DES can be tailored to meet different physicochemical requirements by altering the HBA:HBD ratio or the nature of the compounds. In this study, we utilized the COSMO-RS method to predict the activity coefficients of 12 phenolic compounds in 105 NaDES. These NaDES contained equimolar mixtures of betaine, carnitine, creatine, and ornithine as HBAs and various sugars and amino acids as HBDs. The NaDES were compared to methanol, and several mixtures exhibited higher affinities to all phenolics. The most promising NaDES were betaine-glycerol, betaine-xylitol, and carnitine-urea. We are currently conducting experimental validation of the extraction efficiency of these cosmetically acceptable solvents. In summary, we have identified promising NaDES mixtures that could replace conventional solvents and contribute to the development of sustainable, bio-based extracts.

Acknowledgment: This research was funded by The Science Fund of the Republic of Serbia, Serbian Science and Diaspora Collaboration Program, No. 389927, and the MNTR, contracts No. 451-03-47/2023-01/200168 and 451-03-47/2023-01/200288.
C3  - 59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia
T1  - Screening natural deep eutectic solvents (NaDES) using COSMO-RS for sustainable and environmentally-friendly cosmetic ingredients
IS  - 66
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6222
ER  - 
@conference{
author = "Cvijetić, Ilija and Ivković, Đurđa and Todorović, Petar and Andrić, Filip and Ristivojević, Petar",
year = "2023",
abstract = "DES are mixtures of a hydrogen bond donor (HBD) and a hydrogen bond acceptor (HBA) that, when combined in a specific molar ratio, exhibit a significant decrease in melting point and become liquid at room temperature. DES can be tailored to meet different physicochemical requirements by altering the HBA:HBD ratio or the nature of the compounds. In this study, we utilized the COSMO-RS method to predict the activity coefficients of 12 phenolic compounds in 105 NaDES. These NaDES contained equimolar mixtures of betaine, carnitine, creatine, and ornithine as HBAs and various sugars and amino acids as HBDs. The NaDES were compared to methanol, and several mixtures exhibited higher affinities to all phenolics. The most promising NaDES were betaine-glycerol, betaine-xylitol, and carnitine-urea. We are currently conducting experimental validation of the extraction efficiency of these cosmetically acceptable solvents. In summary, we have identified promising NaDES mixtures that could replace conventional solvents and contribute to the development of sustainable, bio-based extracts.

Acknowledgment: This research was funded by The Science Fund of the Republic of Serbia, Serbian Science and Diaspora Collaboration Program, No. 389927, and the MNTR, contracts No. 451-03-47/2023-01/200168 and 451-03-47/2023-01/200288.",
journal = "59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia",
title = "Screening natural deep eutectic solvents (NaDES) using COSMO-RS for sustainable and environmentally-friendly cosmetic ingredients",
number = "66",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6222"
}
Cvijetić, I., Ivković, Đ., Todorović, P., Andrić, F.,& Ristivojević, P.. (2023). Screening natural deep eutectic solvents (NaDES) using COSMO-RS for sustainable and environmentally-friendly cosmetic ingredients. in 59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia(66).
https://hdl.handle.net/21.15107/rcub_cherry_6222
Cvijetić I, Ivković Đ, Todorović P, Andrić F, Ristivojević P. Screening natural deep eutectic solvents (NaDES) using COSMO-RS for sustainable and environmentally-friendly cosmetic ingredients. in 59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia. 2023;(66).
https://hdl.handle.net/21.15107/rcub_cherry_6222 .
Cvijetić, Ilija, Ivković, Đurđa, Todorović, Petar, Andrić, Filip, Ristivojević, Petar, "Screening natural deep eutectic solvents (NaDES) using COSMO-RS for sustainable and environmentally-friendly cosmetic ingredients" in 59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia, no. 66 (2023),
https://hdl.handle.net/21.15107/rcub_cherry_6222 .

Phenolic profile and in vitro cytotoxic effects of selected herbs with potential skin anti-ageing properties

Ivković, Đurđa; Trifunović, Olga; Andrić, Filip; Krstić-Ristivojević, Maja; Ristivojević, Petar

(2023)

TY  - CONF
AU  - Ivković, Đurđa
AU  - Trifunović, Olga
AU  - Andrić, Filip
AU  - Krstić-Ristivojević, Maja
AU  - Ristivojević, Petar
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6221
AB  - The latest studies show that UV and blue light, emitted by electronic devices with screens, slows the proliferation of the keratinocytes and generates free radicals leading to skin ageing1. Polyphenols, a compounds found in plants, can prevent light-induced damage to the skin. A constant screening of plant extracts is requisite in order to discern light-protective formulations to constitute cosmetic products. Using mass spectrometry, phenolic compounds were identified and quantified in plant extracts from 18 plants grown in Eastern Serbia. The cytotoxicity of the obtained extracts was tested on HaCaT cells (immortalized human keratinocytes) and IC50 values were determined. The obtained extracts are rich mixtures of phenolic compounds that must be dosed appropriately since they also damage skin cells at larger concentrations.

1. Nakashima Y, et al., Free Radic. Biol. Med. 2017, 108, 300–310.

Acknowledgment: This work was supported by The Science Fund of the Republic of Serbia, Serbian Science and Diaspora Collaboration Program, No.6389927, Ministry of Science, Technological Development and Innovation of Republic of Serbia Contract numbers 451-03-47/2023-01/200168 and 451-03-47/2023-01/200288.
C3  - 59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia
T1  - Phenolic profile and in vitro cytotoxic effects of selected herbs with potential skin anti-ageing properties
IS  - 41
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6221
ER  - 
@conference{
author = "Ivković, Đurđa and Trifunović, Olga and Andrić, Filip and Krstić-Ristivojević, Maja and Ristivojević, Petar",
year = "2023",
abstract = "The latest studies show that UV and blue light, emitted by electronic devices with screens, slows the proliferation of the keratinocytes and generates free radicals leading to skin ageing1. Polyphenols, a compounds found in plants, can prevent light-induced damage to the skin. A constant screening of plant extracts is requisite in order to discern light-protective formulations to constitute cosmetic products. Using mass spectrometry, phenolic compounds were identified and quantified in plant extracts from 18 plants grown in Eastern Serbia. The cytotoxicity of the obtained extracts was tested on HaCaT cells (immortalized human keratinocytes) and IC50 values were determined. The obtained extracts are rich mixtures of phenolic compounds that must be dosed appropriately since they also damage skin cells at larger concentrations.

1. Nakashima Y, et al., Free Radic. Biol. Med. 2017, 108, 300–310.

Acknowledgment: This work was supported by The Science Fund of the Republic of Serbia, Serbian Science and Diaspora Collaboration Program, No.6389927, Ministry of Science, Technological Development and Innovation of Republic of Serbia Contract numbers 451-03-47/2023-01/200168 and 451-03-47/2023-01/200288.",
journal = "59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia",
title = "Phenolic profile and in vitro cytotoxic effects of selected herbs with potential skin anti-ageing properties",
number = "41",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6221"
}
Ivković, Đ., Trifunović, O., Andrić, F., Krstić-Ristivojević, M.,& Ristivojević, P.. (2023). Phenolic profile and in vitro cytotoxic effects of selected herbs with potential skin anti-ageing properties. in 59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia(41).
https://hdl.handle.net/21.15107/rcub_cherry_6221
Ivković Đ, Trifunović O, Andrić F, Krstić-Ristivojević M, Ristivojević P. Phenolic profile and in vitro cytotoxic effects of selected herbs with potential skin anti-ageing properties. in 59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia. 2023;(41).
https://hdl.handle.net/21.15107/rcub_cherry_6221 .
Ivković, Đurđa, Trifunović, Olga, Andrić, Filip, Krstić-Ristivojević, Maja, Ristivojević, Petar, "Phenolic profile and in vitro cytotoxic effects of selected herbs with potential skin anti-ageing properties" in 59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia, no. 41 (2023),
https://hdl.handle.net/21.15107/rcub_cherry_6221 .

The phenolic profile and antioxidative activity of seventeen flower petals extracts

Ivković, Đurđa; Topić, Milica; Trifković, Jelena; Krstić-Ristivojević, Maja; Ristivojević, Petar

(2023)

TY  - CONF
AU  - Ivković, Đurđa
AU  - Topić, Milica
AU  - Trifković, Jelena
AU  - Krstić-Ristivojević, Maja
AU  - Ristivojević, Petar
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6219
AB  - Due to their strong antioxidative potential, flower petals are considered important starting materials for the development of cosmetic products1. Present study explored phenolic profile and antioxidative potential of 17 flower petals and their potential application in the cosmetics industry. The phenolic profile of investigated extracts was determined using High-Performance Thin Layer Chromatography (HPTLC). The antioxidative potential was assessed using both ABTS and DPPH spectrophotometric tests, and total phenol content. DPPH-HPTLC assay was applied to identify compounds with the highest antioxidative activity. Five phenols were identified in the investigated extracts. Based on radical antioxidative tests, Paeonia lactifora, Paeonia decora, Rosa istriaca and Pelargonium peltatum were identified as species with the highest antioxidative potential, while gallic acid was recognized as the strongest antioxidants.

1. D. F. Hernandez et all, Crit. Rev. Food. Sci. Nutr, 2021, 61, 3740-3755.

Acknowledgement: This work was supported by The Science Fund of the Republic of Serbia, Serbian Science and Diaspora Collaboration Program, No.6389927.
C3  - 59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia
T1  - The phenolic profile and antioxidative activity of seventeen flower petals extracts
IS  - 44
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6219
ER  - 
@conference{
author = "Ivković, Đurđa and Topić, Milica and Trifković, Jelena and Krstić-Ristivojević, Maja and Ristivojević, Petar",
year = "2023",
abstract = "Due to their strong antioxidative potential, flower petals are considered important starting materials for the development of cosmetic products1. Present study explored phenolic profile and antioxidative potential of 17 flower petals and their potential application in the cosmetics industry. The phenolic profile of investigated extracts was determined using High-Performance Thin Layer Chromatography (HPTLC). The antioxidative potential was assessed using both ABTS and DPPH spectrophotometric tests, and total phenol content. DPPH-HPTLC assay was applied to identify compounds with the highest antioxidative activity. Five phenols were identified in the investigated extracts. Based on radical antioxidative tests, Paeonia lactifora, Paeonia decora, Rosa istriaca and Pelargonium peltatum were identified as species with the highest antioxidative potential, while gallic acid was recognized as the strongest antioxidants.

1. D. F. Hernandez et all, Crit. Rev. Food. Sci. Nutr, 2021, 61, 3740-3755.

Acknowledgement: This work was supported by The Science Fund of the Republic of Serbia, Serbian Science and Diaspora Collaboration Program, No.6389927.",
journal = "59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia",
title = "The phenolic profile and antioxidative activity of seventeen flower petals extracts",
number = "44",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6219"
}
Ivković, Đ., Topić, M., Trifković, J., Krstić-Ristivojević, M.,& Ristivojević, P.. (2023). The phenolic profile and antioxidative activity of seventeen flower petals extracts. in 59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia(44).
https://hdl.handle.net/21.15107/rcub_cherry_6219
Ivković Đ, Topić M, Trifković J, Krstić-Ristivojević M, Ristivojević P. The phenolic profile and antioxidative activity of seventeen flower petals extracts. in 59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia. 2023;(44).
https://hdl.handle.net/21.15107/rcub_cherry_6219 .
Ivković, Đurđa, Topić, Milica, Trifković, Jelena, Krstić-Ristivojević, Maja, Ristivojević, Petar, "The phenolic profile and antioxidative activity of seventeen flower petals extracts" in 59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia, no. 44 (2023),
https://hdl.handle.net/21.15107/rcub_cherry_6219 .

Elastase and tyrosinase inhibitory activity of plant petals cultivated in Serbia

Ivković, Đurđa; Ristivojević, Petar; Krstić-Ristivojević, Maja

(2023)

TY  - CONF
AU  - Ivković, Đurđa
AU  - Ristivojević, Petar
AU  - Krstić-Ristivojević, Maja
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6224
AB  - The cosmetic industry is currently experiencing substantial growth, accompanied by a surge in the number of consumers. Due to natural ingredients' safety and efficiency, an increasingly prominent trend in this industry is the design of herbal-based cosmetic products and formulations. To meet demand, integrating innovative natural resources like plant-based formulations is essential [1]. Skin ageing-related enzymes, elastase and tyrosinase, contribute to the emergence of aesthetic issues such as wrinkles, freckles, and loss of elasticity, as well as hyperpigmentation and melasma [2]. Hence, there is an increasing focus on finding inhibitors for enzymes associated with skin ageing. The fact is that plant metabolites, particularly phenolic acids and flavonoids, are frequently concentrated in plant leaves and flowers. Accordingly, we assessed the inhibitory effects on elastase and tyrosinase in seventeen particularly selected methanolic extracts obtained from various flower petal varieties cultivated in Serbia. Our analysis revealed that petals exhibit significantly more pronounced inhibitory effects, expressed as IC50 values, on elastase compared to tyrosinase. White peony (Paeonia lactifora) (230 ± 1 μg/mL), pelargonium (Pelargonium peltatum) (206 ± 3 μg/mL) and purple rose (Rosa centifolia, purple) (222 ± 8 μg/mL) emerged as the most potent elastase inhibitors, surpassing the reference compound epigallocatechin gallate (348 ± 9 μg/mL). Additionally, the lowest IC50 value for tyrosinase inhibition was attributed to lilac (Syringa vulgaris) petal extract (272 ± 28 μg/mL), which was compared to the standard compound kojic acid (50 ± 14 μg/mL). In conclusion, white peony, pelargonium, purple rose, and lilac represent promising candidates for further investigation and incorporation into cosmetic products, showcasing their potential to effectively address skin-related concerns.

References
1. C. Lourenço-Lopes, M. Fraga-Corral, M. Carpena, Resour. 2020, 9, 101.
2. I. Chiocchio, M. Mandrone, C. Sanna, A. Maxia, M. Tacchini, F. Poli, Ind. Crops Prod. 2018, 122, 498.
Acknowledgements

This work was supported by The Science Fund of the Republic of Serbia, Serbian Science and Diaspora Collaboration Program, No. 6389927, Ministry of Science, Technological Development and Innovation of Republic of Serbia Contract numbers 451-03-47/2023-01/200168 and 451-03-47/2023-01/200288.
C3  - 9th Conference of Young Chemists of Serbia, Book of Abstracts, 4th November 2023, University of Novi Sad - Faculty of Science
T1  - Elastase and tyrosinase inhibitory activity of plant petals cultivated in Serbia
IS  - 132
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6224
ER  - 
@conference{
author = "Ivković, Đurđa and Ristivojević, Petar and Krstić-Ristivojević, Maja",
year = "2023",
abstract = "The cosmetic industry is currently experiencing substantial growth, accompanied by a surge in the number of consumers. Due to natural ingredients' safety and efficiency, an increasingly prominent trend in this industry is the design of herbal-based cosmetic products and formulations. To meet demand, integrating innovative natural resources like plant-based formulations is essential [1]. Skin ageing-related enzymes, elastase and tyrosinase, contribute to the emergence of aesthetic issues such as wrinkles, freckles, and loss of elasticity, as well as hyperpigmentation and melasma [2]. Hence, there is an increasing focus on finding inhibitors for enzymes associated with skin ageing. The fact is that plant metabolites, particularly phenolic acids and flavonoids, are frequently concentrated in plant leaves and flowers. Accordingly, we assessed the inhibitory effects on elastase and tyrosinase in seventeen particularly selected methanolic extracts obtained from various flower petal varieties cultivated in Serbia. Our analysis revealed that petals exhibit significantly more pronounced inhibitory effects, expressed as IC50 values, on elastase compared to tyrosinase. White peony (Paeonia lactifora) (230 ± 1 μg/mL), pelargonium (Pelargonium peltatum) (206 ± 3 μg/mL) and purple rose (Rosa centifolia, purple) (222 ± 8 μg/mL) emerged as the most potent elastase inhibitors, surpassing the reference compound epigallocatechin gallate (348 ± 9 μg/mL). Additionally, the lowest IC50 value for tyrosinase inhibition was attributed to lilac (Syringa vulgaris) petal extract (272 ± 28 μg/mL), which was compared to the standard compound kojic acid (50 ± 14 μg/mL). In conclusion, white peony, pelargonium, purple rose, and lilac represent promising candidates for further investigation and incorporation into cosmetic products, showcasing their potential to effectively address skin-related concerns.

References
1. C. Lourenço-Lopes, M. Fraga-Corral, M. Carpena, Resour. 2020, 9, 101.
2. I. Chiocchio, M. Mandrone, C. Sanna, A. Maxia, M. Tacchini, F. Poli, Ind. Crops Prod. 2018, 122, 498.
Acknowledgements

This work was supported by The Science Fund of the Republic of Serbia, Serbian Science and Diaspora Collaboration Program, No. 6389927, Ministry of Science, Technological Development and Innovation of Republic of Serbia Contract numbers 451-03-47/2023-01/200168 and 451-03-47/2023-01/200288.",
journal = "9th Conference of Young Chemists of Serbia, Book of Abstracts, 4th November 2023, University of Novi Sad - Faculty of Science",
title = "Elastase and tyrosinase inhibitory activity of plant petals cultivated in Serbia",
number = "132",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6224"
}
Ivković, Đ., Ristivojević, P.,& Krstić-Ristivojević, M.. (2023). Elastase and tyrosinase inhibitory activity of plant petals cultivated in Serbia. in 9th Conference of Young Chemists of Serbia, Book of Abstracts, 4th November 2023, University of Novi Sad - Faculty of Science(132).
https://hdl.handle.net/21.15107/rcub_cherry_6224
Ivković Đ, Ristivojević P, Krstić-Ristivojević M. Elastase and tyrosinase inhibitory activity of plant petals cultivated in Serbia. in 9th Conference of Young Chemists of Serbia, Book of Abstracts, 4th November 2023, University of Novi Sad - Faculty of Science. 2023;(132).
https://hdl.handle.net/21.15107/rcub_cherry_6224 .
Ivković, Đurđa, Ristivojević, Petar, Krstić-Ristivojević, Maja, "Elastase and tyrosinase inhibitory activity of plant petals cultivated in Serbia" in 9th Conference of Young Chemists of Serbia, Book of Abstracts, 4th November 2023, University of Novi Sad - Faculty of Science, no. 132 (2023),
https://hdl.handle.net/21.15107/rcub_cherry_6224 .

Skin anti-ageing potential of 18 medicinal herbs collected from Serbia

Ivković, Đurđa; Krstić-Ristivojević, Maja; Jankov, Milica; Milojković-Opsenica, Dušanka; Trifković, Jelena; Andrić, Filip; Ristivojević, Petar

(2022)

TY  - CONF
AU  - Ivković, Đurđa
AU  - Krstić-Ristivojević, Maja
AU  - Jankov, Milica
AU  - Milojković-Opsenica, Dušanka
AU  - Trifković, Jelena
AU  - Andrić, Filip
AU  - Ristivojević, Petar
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6214
AB  - Excess of free radicals in skin causes oxidative stress, which results to skin aging and
appearance of age spots. The enzyme tyrosinase is responsible for mentioned process.
Slowing down of this unwanted process is one of the challenges of modern science. Thus,
the aim of this study is to examine the potential of selected plant extracts to reduce
oxidation stress and the appearance of hyperpigmentation. The extracts were characterized
by the use of high-performance thin-layer chromatography and high-performance liquid
chromatography coupled with mass spectrometry. The antioxidant activity of the extracts
and potential for the inhibition of tyrosinase enzyme were determined. Nineteen phenolic
compounds were quantificated in the tested extracts. The obtained results demonstrate that
the extracts of Morus alba (92%), Rubus (86%) and Agrimona eupatoria (84%) are the
most effective inhibitors. The Teucrium chamaedrys and Agrimona eupatoria showed high
values of antioxidant activity. The listed samples are commercial.
C3  - 58th Meeting of the Serbian Chemical Society, Belgrade, Serbia, 9th-10th June, 2022. In: Book of Abstracts and Proceedings
T1  - Skin anti-ageing potential of 18 medicinal herbs collected from Serbia
IS  - 44
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6214
ER  - 
@conference{
author = "Ivković, Đurđa and Krstić-Ristivojević, Maja and Jankov, Milica and Milojković-Opsenica, Dušanka and Trifković, Jelena and Andrić, Filip and Ristivojević, Petar",
year = "2022",
abstract = "Excess of free radicals in skin causes oxidative stress, which results to skin aging and
appearance of age spots. The enzyme tyrosinase is responsible for mentioned process.
Slowing down of this unwanted process is one of the challenges of modern science. Thus,
the aim of this study is to examine the potential of selected plant extracts to reduce
oxidation stress and the appearance of hyperpigmentation. The extracts were characterized
by the use of high-performance thin-layer chromatography and high-performance liquid
chromatography coupled with mass spectrometry. The antioxidant activity of the extracts
and potential for the inhibition of tyrosinase enzyme were determined. Nineteen phenolic
compounds were quantificated in the tested extracts. The obtained results demonstrate that
the extracts of Morus alba (92%), Rubus (86%) and Agrimona eupatoria (84%) are the
most effective inhibitors. The Teucrium chamaedrys and Agrimona eupatoria showed high
values of antioxidant activity. The listed samples are commercial.",
journal = "58th Meeting of the Serbian Chemical Society, Belgrade, Serbia, 9th-10th June, 2022. In: Book of Abstracts and Proceedings",
title = "Skin anti-ageing potential of 18 medicinal herbs collected from Serbia",
number = "44",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6214"
}
Ivković, Đ., Krstić-Ristivojević, M., Jankov, M., Milojković-Opsenica, D., Trifković, J., Andrić, F.,& Ristivojević, P.. (2022). Skin anti-ageing potential of 18 medicinal herbs collected from Serbia. in 58th Meeting of the Serbian Chemical Society, Belgrade, Serbia, 9th-10th June, 2022. In: Book of Abstracts and Proceedings(44).
https://hdl.handle.net/21.15107/rcub_cherry_6214
Ivković Đ, Krstić-Ristivojević M, Jankov M, Milojković-Opsenica D, Trifković J, Andrić F, Ristivojević P. Skin anti-ageing potential of 18 medicinal herbs collected from Serbia. in 58th Meeting of the Serbian Chemical Society, Belgrade, Serbia, 9th-10th June, 2022. In: Book of Abstracts and Proceedings. 2022;(44).
https://hdl.handle.net/21.15107/rcub_cherry_6214 .
Ivković, Đurđa, Krstić-Ristivojević, Maja, Jankov, Milica, Milojković-Opsenica, Dušanka, Trifković, Jelena, Andrić, Filip, Ristivojević, Petar, "Skin anti-ageing potential of 18 medicinal herbs collected from Serbia" in 58th Meeting of the Serbian Chemical Society, Belgrade, Serbia, 9th-10th June, 2022. In: Book of Abstracts and Proceedings, no. 44 (2022),
https://hdl.handle.net/21.15107/rcub_cherry_6214 .

Total phenolic, flavonoid contents and radical scavenging activities of NADES- based propolis extracts

Ivković, Đurđa; Lazović, Mila; Jankov, Milica; Ristivojević, Petar

(2022)

TY  - CONF
AU  - Ivković, Đurđa
AU  - Lazović, Mila
AU  - Jankov, Milica
AU  - Ristivojević, Petar
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6223
AB  - Propolis is a resinous substance collected by honeybees (Apis mellifera L.) from
different plant parts such as branches, plant buds, leaves, and exudates partially digested
by β-glycosidase from bees’ saliva, and after that mixed with beeswax. It is commonly
used in folk medicine to prevent and treat colds, ulcers, rheumatism, diabetes, and dental
caries. Commercially available products most often comprise ethanolic extracts of
propolis. However, high alcohol content and strong residual flavour make such products
unsuitable for patients intolerant to alcohol, especially children. Due to mentioned
drawbacks, propylene glycolic, aqueous, fructose, or olive oil propolis extracts are
commonly found on the market as safer alternatives. These solvents are more appealing
options but the extraction efficiency is up to 10 times lower compared to ethanol. Thus,
there are high demands for the development of effective and ethanol-free extractions1,2
.
The overall aim of the study is to determine total phenolic, flavonoid content and radical
scavenging activity of high-quality and natural-based propolis extract enriched with
bioactives using new generation of solvents as Natural Deep Eutectic Solvents
(NADES)1
. Thirty-eight different green NADES have been used for the extraction of
phenols from poplar types of propolis. The NADES were prepared by mixing different
molar ratios of polycarboxylic acids, amino acids, glycerol, urea, potassium acetate,
choline chloride and ethylene glycol. The highest values of TPC, TFC, and DPPH were
obtained using following NADES systems: lactic acid/glycerol=1/1; lactic
acid/glycine=3/1; glycerol/proline=1/1; choline chloride/succinic acid=2/1 and choline
chloride/ethylene glycol=1/4.

References
1. V. Bankova, B. Trusheva & Milena Popova, J. Apic. Res. 2021, 60, 734.
2. L. Kubiliene, V. Laugaliene, A. Pavilonis, A. Maruska, D. Majiene, K. Barcauskaite,
BMC Complement. Altern. Med. 2015, 15, 1.

Acknowledgment
This work was supported by the Ministry of Education, Science and Technological
Development of the Republic of Serbia, Contract numbers: 451-03-68/2022-14/200168
and 451-03-68/2022-14/200288.
C3  - 8th Conference of Young Chemists of Serbia, Belgrade, Serbia, 29th October, 2022. In: Book of Abstracts
T1  - Total phenolic, flavonoid contents and radical scavenging activities of NADES- based propolis extracts
IS  - 35
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6223
ER  - 
@conference{
author = "Ivković, Đurđa and Lazović, Mila and Jankov, Milica and Ristivojević, Petar",
year = "2022",
abstract = "Propolis is a resinous substance collected by honeybees (Apis mellifera L.) from
different plant parts such as branches, plant buds, leaves, and exudates partially digested
by β-glycosidase from bees’ saliva, and after that mixed with beeswax. It is commonly
used in folk medicine to prevent and treat colds, ulcers, rheumatism, diabetes, and dental
caries. Commercially available products most often comprise ethanolic extracts of
propolis. However, high alcohol content and strong residual flavour make such products
unsuitable for patients intolerant to alcohol, especially children. Due to mentioned
drawbacks, propylene glycolic, aqueous, fructose, or olive oil propolis extracts are
commonly found on the market as safer alternatives. These solvents are more appealing
options but the extraction efficiency is up to 10 times lower compared to ethanol. Thus,
there are high demands for the development of effective and ethanol-free extractions1,2
.
The overall aim of the study is to determine total phenolic, flavonoid content and radical
scavenging activity of high-quality and natural-based propolis extract enriched with
bioactives using new generation of solvents as Natural Deep Eutectic Solvents
(NADES)1
. Thirty-eight different green NADES have been used for the extraction of
phenols from poplar types of propolis. The NADES were prepared by mixing different
molar ratios of polycarboxylic acids, amino acids, glycerol, urea, potassium acetate,
choline chloride and ethylene glycol. The highest values of TPC, TFC, and DPPH were
obtained using following NADES systems: lactic acid/glycerol=1/1; lactic
acid/glycine=3/1; glycerol/proline=1/1; choline chloride/succinic acid=2/1 and choline
chloride/ethylene glycol=1/4.

References
1. V. Bankova, B. Trusheva & Milena Popova, J. Apic. Res. 2021, 60, 734.
2. L. Kubiliene, V. Laugaliene, A. Pavilonis, A. Maruska, D. Majiene, K. Barcauskaite,
BMC Complement. Altern. Med. 2015, 15, 1.

Acknowledgment
This work was supported by the Ministry of Education, Science and Technological
Development of the Republic of Serbia, Contract numbers: 451-03-68/2022-14/200168
and 451-03-68/2022-14/200288.",
journal = "8th Conference of Young Chemists of Serbia, Belgrade, Serbia, 29th October, 2022. In: Book of Abstracts",
title = "Total phenolic, flavonoid contents and radical scavenging activities of NADES- based propolis extracts",
number = "35",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6223"
}
Ivković, Đ., Lazović, M., Jankov, M.,& Ristivojević, P.. (2022). Total phenolic, flavonoid contents and radical scavenging activities of NADES- based propolis extracts. in 8th Conference of Young Chemists of Serbia, Belgrade, Serbia, 29th October, 2022. In: Book of Abstracts(35).
https://hdl.handle.net/21.15107/rcub_cherry_6223
Ivković Đ, Lazović M, Jankov M, Ristivojević P. Total phenolic, flavonoid contents and radical scavenging activities of NADES- based propolis extracts. in 8th Conference of Young Chemists of Serbia, Belgrade, Serbia, 29th October, 2022. In: Book of Abstracts. 2022;(35).
https://hdl.handle.net/21.15107/rcub_cherry_6223 .
Ivković, Đurđa, Lazović, Mila, Jankov, Milica, Ristivojević, Petar, "Total phenolic, flavonoid contents and radical scavenging activities of NADES- based propolis extracts" in 8th Conference of Young Chemists of Serbia, Belgrade, Serbia, 29th October, 2022. In: Book of Abstracts, no. 35 (2022),
https://hdl.handle.net/21.15107/rcub_cherry_6223 .

Hemijski profil i antioksidativna aktivnost biljnih vrsta potencijalno značajnih za kozmetičku industriju

Ivković, Đurđa

(2021)

TY  - THES
AU  - Ivković, Đurđa
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4558
AB  - Lekovite biljke predstavljaju neiscrpni izvor biološki aktvinih jedinjenja koja se u većini slučajeva mogu ponašati kao antioksidansi. U okviru ovog rada ispitaivan je profil biljnih metabolita i antioksidativna aktivnost 22 biljke koje se mogu pronaći na teritoriji Republike Srbije. Metaboliti su ekstrahovani iz biljnog materijala ekstrakcijom potpomognutom ultrazvukom upotrebom četiri konvencionalna organska rastvarača. Ispitivana je antioksidativna aktivnost dobijenih ekstrakata u cilju iznalaženja najaktivnijih biljnih ekstrakata dok je tankoslojna hromatografija praćena hemometrijskom analizom upotrebljena u cilju pronalaženja sličnosti među biljnim vrstama koje bi se potencijalno mogle koristiti kao alternativne biljke u kozmetičkoj industriji. Na osnovu dobijenih rezultata zaključeno je da zeleni čaj, petrovac, podubica, iva, glog i origano predstavljaju bogat izvor biološki aktivnih jedinjenja i poseduju izražen antioksidativni potencijal. Takođe, zaključeno je da sistemi rastvarača etanol – voda i metilenhlorid – metanol ekstrahuju jedan tip aktivnih jedinjenja dok metanol ekstrahuje drugačije aktivne supstance iz biljaka, što ukazuje na veliki biološki i hemijski diverzitet ekstrahovanih biljaka.
T1  - Hemijski profil i antioksidativna aktivnost biljnih vrsta potencijalno značajnih za kozmetičku industriju
SP  - 1
EP  - 54
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4558
ER  - 
@mastersthesis{
author = "Ivković, Đurđa",
year = "2021",
abstract = "Lekovite biljke predstavljaju neiscrpni izvor biološki aktvinih jedinjenja koja se u većini slučajeva mogu ponašati kao antioksidansi. U okviru ovog rada ispitaivan je profil biljnih metabolita i antioksidativna aktivnost 22 biljke koje se mogu pronaći na teritoriji Republike Srbije. Metaboliti su ekstrahovani iz biljnog materijala ekstrakcijom potpomognutom ultrazvukom upotrebom četiri konvencionalna organska rastvarača. Ispitivana je antioksidativna aktivnost dobijenih ekstrakata u cilju iznalaženja najaktivnijih biljnih ekstrakata dok je tankoslojna hromatografija praćena hemometrijskom analizom upotrebljena u cilju pronalaženja sličnosti među biljnim vrstama koje bi se potencijalno mogle koristiti kao alternativne biljke u kozmetičkoj industriji. Na osnovu dobijenih rezultata zaključeno je da zeleni čaj, petrovac, podubica, iva, glog i origano predstavljaju bogat izvor biološki aktivnih jedinjenja i poseduju izražen antioksidativni potencijal. Takođe, zaključeno je da sistemi rastvarača etanol – voda i metilenhlorid – metanol ekstrahuju jedan tip aktivnih jedinjenja dok metanol ekstrahuje drugačije aktivne supstance iz biljaka, što ukazuje na veliki biološki i hemijski diverzitet ekstrahovanih biljaka.",
title = "Hemijski profil i antioksidativna aktivnost biljnih vrsta potencijalno značajnih za kozmetičku industriju",
pages = "1-54",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4558"
}
Ivković, Đ.. (2021). Hemijski profil i antioksidativna aktivnost biljnih vrsta potencijalno značajnih za kozmetičku industriju. , 1-54.
https://hdl.handle.net/21.15107/rcub_cherry_4558
Ivković Đ. Hemijski profil i antioksidativna aktivnost biljnih vrsta potencijalno značajnih za kozmetičku industriju. 2021;:1-54.
https://hdl.handle.net/21.15107/rcub_cherry_4558 .
Ivković, Đurđa, "Hemijski profil i antioksidativna aktivnost biljnih vrsta potencijalno značajnih za kozmetičku industriju" (2021):1-54,
https://hdl.handle.net/21.15107/rcub_cherry_4558 .

Studija fotokatalitičke aktivacije vinil-jodida u prisustvu derivata antrona pomoću vidljive svetlosti

Ivković, Đurđa

(2020)

TY  - THES
AU  - Ivković, Đurđa
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4018
AB  - Aktivacija vinil-halogenida fotoredoks katalizom pomoću vidljive svetlosti nije dovoljno istražena. Cilj ovog rada bio je testiranje organskih fotoredoks katalizatora na bazi antrona kako bi se omogućila 5-egzo-ciklizacije vinil-jodida koji u pogodnom položaju poseduju dvostuku vezu. Sintetisan je supstrat, očekivani proizvod reakcije pomoću odvojene metode i dva organska fotokatalizatora, antron i akridon. Određen je redoks potencijal
supstrata pomoću ciklične voltametrije. Prilikom fotokatalitičke aktivacije vinil-jodida pomoću vidljive svetlosti u prisustvu antrona očekivani proizvod reakcije nije detektovan, a konverzija supstrata je bila nepotpuna. Kada je akridon korišćen kao katalizator konverzija supstrata je bila skoro kvantitativna. Dodatno, antron i akridon su testirani kao fotokatalizatori na model sistemu iz literature, u reakciji aktivacije aril-halogenida: ishodi ovih eksperimenata su u skladu sa literaturom što ukazuje na to da eksperimentalna tehnika rada, kvalitet sintetisanih fotokatalizatora i čistoća rastvarača ispunjavaju kriterijume neophodne za izvođenje fotohemijskih reakcija.
T1  - Studija fotokatalitičke aktivacije vinil-jodida u prisustvu derivata antrona pomoću vidljive svetlosti
SP  - 1
EP  - 45
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4018
ER  - 
@misc{
author = "Ivković, Đurđa",
year = "2020",
abstract = "Aktivacija vinil-halogenida fotoredoks katalizom pomoću vidljive svetlosti nije dovoljno istražena. Cilj ovog rada bio je testiranje organskih fotoredoks katalizatora na bazi antrona kako bi se omogućila 5-egzo-ciklizacije vinil-jodida koji u pogodnom položaju poseduju dvostuku vezu. Sintetisan je supstrat, očekivani proizvod reakcije pomoću odvojene metode i dva organska fotokatalizatora, antron i akridon. Određen je redoks potencijal
supstrata pomoću ciklične voltametrije. Prilikom fotokatalitičke aktivacije vinil-jodida pomoću vidljive svetlosti u prisustvu antrona očekivani proizvod reakcije nije detektovan, a konverzija supstrata je bila nepotpuna. Kada je akridon korišćen kao katalizator konverzija supstrata je bila skoro kvantitativna. Dodatno, antron i akridon su testirani kao fotokatalizatori na model sistemu iz literature, u reakciji aktivacije aril-halogenida: ishodi ovih eksperimenata su u skladu sa literaturom što ukazuje na to da eksperimentalna tehnika rada, kvalitet sintetisanih fotokatalizatora i čistoća rastvarača ispunjavaju kriterijume neophodne za izvođenje fotohemijskih reakcija.",
title = "Studija fotokatalitičke aktivacije vinil-jodida u prisustvu derivata antrona pomoću vidljive svetlosti",
pages = "1-45",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4018"
}
Ivković, Đ.. (2020). Studija fotokatalitičke aktivacije vinil-jodida u prisustvu derivata antrona pomoću vidljive svetlosti. , 1-45.
https://hdl.handle.net/21.15107/rcub_cherry_4018
Ivković Đ. Studija fotokatalitičke aktivacije vinil-jodida u prisustvu derivata antrona pomoću vidljive svetlosti. 2020;:1-45.
https://hdl.handle.net/21.15107/rcub_cherry_4018 .
Ivković, Đurđa, "Studija fotokatalitičke aktivacije vinil-jodida u prisustvu derivata antrona pomoću vidljive svetlosti" (2020):1-45,
https://hdl.handle.net/21.15107/rcub_cherry_4018 .