TY  - JOUR
AU  - Knežević, Sara
AU  - Ognjanović, Miloš
AU  - Gavrović-Jankulović, Marija
AU  - Đurašinović, Tatjana
AU  - Antić, Bratislav
AU  - Vranješ-Đurić, Sanja
AU  - Stanković, Dalibor
PY  - 2022
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4720
AB  - S-Adenosyl-L-Homocysteine (AdoHcy) is a crucial pathological factor in homocysteine-associated disorders. We developed an impedimetric approach for single drop S-Adenosyl-L-Homocysteine detection, based on S-Adenosyl-L-Homocysteine hydrolase (SAH), produced in the prokaryotic expression system (E. coli) by recombinant DNA technology, immobilized on citrate acid-coated gallium oxyhydroxide dispersed over single-walled carbon nanotubes (CA/GaO(OH)@SWCNT). The proposed biosensor offers detection of AdoHcy, with a limit of detection (LOD) of 0.17 μM. with operating linear range from 1 to 44 μM. The remarkable stability of gallium oxyhydroxide crystal was further improved by citric acid coating and its optical, electrical and physical anisotropy was skipped using SWCNTs.
PB  - Wiley
T2  - Electroanalysis
T1  - S-Adenosyl-L-Homocysteine Hydrolase Immobilized on Citric Acid-capped Gallium Oxyhydroxide on SWCNTs Modified Electrode for AdoHcy Impedimetric Sensing
VL  - 34
IS  - 1
SP  - 15
EP  - 24
DO  - 10.1002/elan.202100362
ER  - 

@article{
author = "Knežević, Sara and Ognjanović, Miloš and Gavrović-Jankulović, Marija and Đurašinović, Tatjana and Antić, Bratislav and Vranješ-Đurić, Sanja and Stanković, Dalibor",
year = "2022",
abstract = "S-Adenosyl-L-Homocysteine (AdoHcy) is a crucial pathological factor in homocysteine-associated disorders. We developed an impedimetric approach for single drop S-Adenosyl-L-Homocysteine detection, based on S-Adenosyl-L-Homocysteine hydrolase (SAH), produced in the prokaryotic expression system (E. coli) by recombinant DNA technology, immobilized on citrate acid-coated gallium oxyhydroxide dispersed over single-walled carbon nanotubes (CA/GaO(OH)@SWCNT). The proposed biosensor offers detection of AdoHcy, with a limit of detection (LOD) of 0.17 μM. with operating linear range from 1 to 44 μM. The remarkable stability of gallium oxyhydroxide crystal was further improved by citric acid coating and its optical, electrical and physical anisotropy was skipped using SWCNTs.",
publisher = "Wiley",
journal = "Electroanalysis",
title = "S-Adenosyl-L-Homocysteine Hydrolase Immobilized on Citric Acid-capped Gallium Oxyhydroxide on SWCNTs Modified Electrode for AdoHcy Impedimetric Sensing",
volume = "34",
number = "1",
pages = "15-24",
doi = "10.1002/elan.202100362"
}

Knežević, S., Ognjanović, M., Gavrović-Jankulović, M., Đurašinović, T., Antić, B., Vranješ-Đurić, S.,& Stanković, D.. (2022). S-Adenosyl-L-Homocysteine Hydrolase Immobilized on Citric Acid-capped Gallium Oxyhydroxide on SWCNTs Modified Electrode for AdoHcy Impedimetric Sensing. in Electroanalysis
Wiley., 34(1), 15-24.
https://doi.org/10.1002/elan.202100362

Knežević S, Ognjanović M, Gavrović-Jankulović M, Đurašinović T, Antić B, Vranješ-Đurić S, Stanković D. S-Adenosyl-L-Homocysteine Hydrolase Immobilized on Citric Acid-capped Gallium Oxyhydroxide on SWCNTs Modified Electrode for AdoHcy Impedimetric Sensing. in Electroanalysis. 2022;34(1):15-24.
doi:10.1002/elan.202100362 .

Knežević, Sara, Ognjanović, Miloš, Gavrović-Jankulović, Marija, Đurašinović, Tatjana, Antić, Bratislav, Vranješ-Đurić, Sanja, Stanković, Dalibor, "S-Adenosyl-L-Homocysteine Hydrolase Immobilized on Citric Acid-capped Gallium Oxyhydroxide on SWCNTs Modified Electrode for AdoHcy Impedimetric Sensing" in Electroanalysis, 34, no. 1 (2022):15-24,
https://doi.org/10.1002/elan.202100362 . .

TY  - JOUR
AU  - Mirković, Marija D.
AU  - Radović, Magdalena
AU  - Stanković, Dalibor
AU  - Vranješ-Đurić, Sanja
AU  - Janković, Drina
AU  - Petrović, Djordje
AU  - Mihajlović-Lalić, Ljiljana
AU  - Prijović, Željko
AU  - Milanović, Zorana
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5135
AB  - Two new Schiff base cobalt(III) ([Co(LH)Cl2], 1) and nickel(II) ([Ni(LH)ClO4], 2) complexes with a diimine-dioxime ligand, (4,9-diaza-3,10-diethyl-3,9-dodecadiene-2,11-dione bis oxime (LH2)), were synthesized and characterized. The compounds were obtained in MeOH from corresponding metal salts and LH2 in molar ratio 1:1 and further characterized by mass spectrometry, IR spectroscopy, electrochemistry, and elemental analysis. Previously reported copper(II) analog, ([Cu2(LH)2]·(ClO4)2, 3) was joined to 1 and 2, and the three metal analogs, 1-3, were further investigated in terms of their electrochemical behavior. The binding studies of the complexes with deoxyribonucleic acid (DNA) and human serum albumin (HSA) were carried out using both spectrophotometric and electrochemical methods. All three complexes exhibit binding affinity towards the DNA chain through intercalative interaction. The binding reaction with HSA showed for 1 and 3 complexes decrease in the peak current obtained in the case of complexes before the addition of HSA, while resulted compound obtained from Ni complex – HSA possesses the same electroactivity as starting complex. Furthermore, the cytotoxicity of LH2 as well as its metal complexes, and cisplatin were evaluated on CT-26 mouse colon carcinoma and human LS174T cancer cell lines employing MTT assay. The copper(II) complex exhibited very promising anticancer activity compared with cisplatin.
PB  - Taylor & Francis Ltd
T2  - Journal of Coordination Chemistry
T1  - Co(III), Ni(II), and Cu(II) complexes with tetradentate Schiff base ligand: Synthesis, Characterization, Electrochemical Behavior, Binding assessment and In vitro cytotoxicity activity
VL  - 75
IS  - 1-2
DO  - 10.1080/00958972.2022.2032683
ER  - 

@article{
author = "Mirković, Marija D. and Radović, Magdalena and Stanković, Dalibor and Vranješ-Đurić, Sanja and Janković, Drina and Petrović, Djordje and Mihajlović-Lalić, Ljiljana and Prijović, Željko and Milanović, Zorana",
year = "2022",
abstract = "Two new Schiff base cobalt(III) ([Co(LH)Cl2], 1) and nickel(II) ([Ni(LH)ClO4], 2) complexes with a diimine-dioxime ligand, (4,9-diaza-3,10-diethyl-3,9-dodecadiene-2,11-dione bis oxime (LH2)), were synthesized and characterized. The compounds were obtained in MeOH from corresponding metal salts and LH2 in molar ratio 1:1 and further characterized by mass spectrometry, IR spectroscopy, electrochemistry, and elemental analysis. Previously reported copper(II) analog, ([Cu2(LH)2]·(ClO4)2, 3) was joined to 1 and 2, and the three metal analogs, 1-3, were further investigated in terms of their electrochemical behavior. The binding studies of the complexes with deoxyribonucleic acid (DNA) and human serum albumin (HSA) were carried out using both spectrophotometric and electrochemical methods. All three complexes exhibit binding affinity towards the DNA chain through intercalative interaction. The binding reaction with HSA showed for 1 and 3 complexes decrease in the peak current obtained in the case of complexes before the addition of HSA, while resulted compound obtained from Ni complex – HSA possesses the same electroactivity as starting complex. Furthermore, the cytotoxicity of LH2 as well as its metal complexes, and cisplatin were evaluated on CT-26 mouse colon carcinoma and human LS174T cancer cell lines employing MTT assay. The copper(II) complex exhibited very promising anticancer activity compared with cisplatin.",
publisher = "Taylor & Francis Ltd",
journal = "Journal of Coordination Chemistry",
title = "Co(III), Ni(II), and Cu(II) complexes with tetradentate Schiff base ligand: Synthesis, Characterization, Electrochemical Behavior, Binding assessment and In vitro cytotoxicity activity",
volume = "75",
number = "1-2",
doi = "10.1080/00958972.2022.2032683"
}

Mirković, M. D., Radović, M., Stanković, D., Vranješ-Đurić, S., Janković, D., Petrović, D., Mihajlović-Lalić, L., Prijović, Ž.,& Milanović, Z.. (2022). Co(III), Ni(II), and Cu(II) complexes with tetradentate Schiff base ligand: Synthesis, Characterization, Electrochemical Behavior, Binding assessment and In vitro cytotoxicity activity. in Journal of Coordination Chemistry
Taylor & Francis Ltd., 75(1-2).
https://doi.org/10.1080/00958972.2022.2032683

Mirković MD, Radović M, Stanković D, Vranješ-Đurić S, Janković D, Petrović D, Mihajlović-Lalić L, Prijović Ž, Milanović Z. Co(III), Ni(II), and Cu(II) complexes with tetradentate Schiff base ligand: Synthesis, Characterization, Electrochemical Behavior, Binding assessment and In vitro cytotoxicity activity. in Journal of Coordination Chemistry. 2022;75(1-2).
doi:10.1080/00958972.2022.2032683 .

Mirković, Marija D., Radović, Magdalena, Stanković, Dalibor, Vranješ-Đurić, Sanja, Janković, Drina, Petrović, Djordje, Mihajlović-Lalić, Ljiljana, Prijović, Željko, Milanović, Zorana, "Co(III), Ni(II), and Cu(II) complexes with tetradentate Schiff base ligand: Synthesis, Characterization, Electrochemical Behavior, Binding assessment and In vitro cytotoxicity activity" in Journal of Coordination Chemistry, 75, no. 1-2 (2022),
https://doi.org/10.1080/00958972.2022.2032683 . .

TY  - DATA
AU  - Smailagić, Anita
AU  - Stanković, Dalibor
AU  - Vranješ-Đurić, Sanja
AU  - Veljović, Sonja
AU  - Dabić Zagorac, Dragana
AU  - Manojlović, Dragan D.
AU  - Natić, Maja
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4456
PB  - Elsevier
T2  - Food Chemistry
T1  - Supplementary data for the article: Smailagić, A.; Stanković, D. M.; Vranješ Đurić, S.; Veljović, S.; Dabić Zagorac, D.; Manojlović, D.; Natić, M. Influence of Extraction Time, Solvent and Wood Specie on Experimentally Aged Spirits – A Simple Tool to Differentiate Wood Species Used in Cooperage. Food Chemistry 2021, 346, 128896. https://doi.org/10.1016/j.foodchem.2020.128896.
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4456
ER  - 

@misc{
author = "Smailagić, Anita and Stanković, Dalibor and Vranješ-Đurić, Sanja and Veljović, Sonja and Dabić Zagorac, Dragana and Manojlović, Dragan D. and Natić, Maja",
year = "2021",
publisher = "Elsevier",
journal = "Food Chemistry",
title = "Supplementary data for the article: Smailagić, A.; Stanković, D. M.; Vranješ Đurić, S.; Veljović, S.; Dabić Zagorac, D.; Manojlović, D.; Natić, M. Influence of Extraction Time, Solvent and Wood Specie on Experimentally Aged Spirits – A Simple Tool to Differentiate Wood Species Used in Cooperage. Food Chemistry 2021, 346, 128896. https://doi.org/10.1016/j.foodchem.2020.128896.",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4456"
}

Smailagić, A., Stanković, D., Vranješ-Đurić, S., Veljović, S., Dabić Zagorac, D., Manojlović, D. D.,& Natić, M.. (2021). Supplementary data for the article: Smailagić, A.; Stanković, D. M.; Vranješ Đurić, S.; Veljović, S.; Dabić Zagorac, D.; Manojlović, D.; Natić, M. Influence of Extraction Time, Solvent and Wood Specie on Experimentally Aged Spirits – A Simple Tool to Differentiate Wood Species Used in Cooperage. Food Chemistry 2021, 346, 128896. https://doi.org/10.1016/j.foodchem.2020.128896.. in Food Chemistry
Elsevier..
https://hdl.handle.net/21.15107/rcub_cherry_4456

Smailagić A, Stanković D, Vranješ-Đurić S, Veljović S, Dabić Zagorac D, Manojlović DD, Natić M. Supplementary data for the article: Smailagić, A.; Stanković, D. M.; Vranješ Đurić, S.; Veljović, S.; Dabić Zagorac, D.; Manojlović, D.; Natić, M. Influence of Extraction Time, Solvent and Wood Specie on Experimentally Aged Spirits – A Simple Tool to Differentiate Wood Species Used in Cooperage. Food Chemistry 2021, 346, 128896. https://doi.org/10.1016/j.foodchem.2020.128896.. in Food Chemistry. 2021;.
https://hdl.handle.net/21.15107/rcub_cherry_4456 .

Smailagić, Anita, Stanković, Dalibor, Vranješ-Đurić, Sanja, Veljović, Sonja, Dabić Zagorac, Dragana, Manojlović, Dragan D., Natić, Maja, "Supplementary data for the article: Smailagić, A.; Stanković, D. M.; Vranješ Đurić, S.; Veljović, S.; Dabić Zagorac, D.; Manojlović, D.; Natić, M. Influence of Extraction Time, Solvent and Wood Specie on Experimentally Aged Spirits – A Simple Tool to Differentiate Wood Species Used in Cooperage. Food Chemistry 2021, 346, 128896. https://doi.org/10.1016/j.foodchem.2020.128896." in Food Chemistry (2021),
https://hdl.handle.net/21.15107/rcub_cherry_4456 .

TY  - JOUR
AU  - Smailagić, Anita
AU  - Stanković, Dalibor
AU  - Vranješ-Đurić, Sanja
AU  - Veljović, Sonja
AU  - Dabić Zagorac, Dragana
AU  - Manojlović, Dragan D.
AU  - Natić, Maja
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4455
AB  - Type of the wood used for the aging highly influences the quality of alcoholic beverages. In this research we explored the potential of cyclic voltammetry (CV) and differential pulse voltammetry (DPV) to establish fingerprints characteristic for each wood and to enable determining the type of the wood used in the aging process. Eleven different wood samples were used to prepare three different types of spirits during 15 months. The highest extraction rate was obtained during the first month, while further aging was followed with almost constant amount of extracted polyphenols. Black locust, myrobalan plum, and mulberry extracts were discriminated from the spirits aged in oak and wild cherry wood when statistical analysis was applied. Although clear classification of all samples was not achieved, this long term study demonstrated a potential of both CV and DPV for differentiating wood species used in the aging, hence in the quality control of spirits. © 2020 Elsevier Ltd
PB  - Elsevier
T2  - Food Chemistry
T2  - Food Chemistry
T2  - Food Chemistry
T1  - Influence of extraction time, solvent and wood specie on experimentally aged spirits – A simple tool to differentiate wood species used in cooperage
VL  - 346
DO  - 10.1016/j.foodchem.2020.128896
ER  - 

@article{
author = "Smailagić, Anita and Stanković, Dalibor and Vranješ-Đurić, Sanja and Veljović, Sonja and Dabić Zagorac, Dragana and Manojlović, Dragan D. and Natić, Maja",
year = "2021",
abstract = "Type of the wood used for the aging highly influences the quality of alcoholic beverages. In this research we explored the potential of cyclic voltammetry (CV) and differential pulse voltammetry (DPV) to establish fingerprints characteristic for each wood and to enable determining the type of the wood used in the aging process. Eleven different wood samples were used to prepare three different types of spirits during 15 months. The highest extraction rate was obtained during the first month, while further aging was followed with almost constant amount of extracted polyphenols. Black locust, myrobalan plum, and mulberry extracts were discriminated from the spirits aged in oak and wild cherry wood when statistical analysis was applied. Although clear classification of all samples was not achieved, this long term study demonstrated a potential of both CV and DPV for differentiating wood species used in the aging, hence in the quality control of spirits. © 2020 Elsevier Ltd",
publisher = "Elsevier",
journal = "Food Chemistry, Food Chemistry, Food Chemistry",
title = "Influence of extraction time, solvent and wood specie on experimentally aged spirits – A simple tool to differentiate wood species used in cooperage",
volume = "346",
doi = "10.1016/j.foodchem.2020.128896"
}

Smailagić, A., Stanković, D., Vranješ-Đurić, S., Veljović, S., Dabić Zagorac, D., Manojlović, D. D.,& Natić, M.. (2021). Influence of extraction time, solvent and wood specie on experimentally aged spirits – A simple tool to differentiate wood species used in cooperage. in Food Chemistry
Elsevier., 346.
https://doi.org/10.1016/j.foodchem.2020.128896

Smailagić A, Stanković D, Vranješ-Đurić S, Veljović S, Dabić Zagorac D, Manojlović DD, Natić M. Influence of extraction time, solvent and wood specie on experimentally aged spirits – A simple tool to differentiate wood species used in cooperage. in Food Chemistry. 2021;346.
doi:10.1016/j.foodchem.2020.128896 .

Smailagić, Anita, Stanković, Dalibor, Vranješ-Đurić, Sanja, Veljović, Sonja, Dabić Zagorac, Dragana, Manojlović, Dragan D., Natić, Maja, "Influence of extraction time, solvent and wood specie on experimentally aged spirits – A simple tool to differentiate wood species used in cooperage" in Food Chemistry, 346 (2021),
https://doi.org/10.1016/j.foodchem.2020.128896 . .

TY  - JOUR
AU  - Stanković, Dalibor
AU  - Ognjanović, Miloš
AU  - Fabián, Martin
AU  - Avdin, Vyacheslav Viktorovich
AU  - Manojlović, Dragan D.
AU  - Vranješ-Đurić, Sanja
AU  - Petković, Branka B.
PY  - 2021
UR  - https://www.sciencedirect.com/science/article/pii/S2468023021002881
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4545
AB  - The goal of this work was to develop green electrode material that unites all advantages of domestic made, synthesized porous carbon powder and ceria dioxide nanoparticles known due to exceptional catalytic properties. Thermal decomposition of Novolac phenol-formaldehyde resin and cerium sulfate resulting in producing a high-performance CeO2 porous carbon material highly sensitive to dopamine (DA) electrooxidation. Morphological and structural characteristics of the material were determined by SEM and XRD measurements, while electrochemical characterization was performed by EIS and CV. The sensitivity of DA determination on the proposed CeO2-doped carbon material was enhanced by adding multi-wall carbon nanotubes to finally prepare a mixture for a specific carbon paste electrode (TPCeO2&MWCNT@CPE). SWV technique was used for quantification of dopamine in Britton-Robinson buffer pH 6 in the concentration range of 0.5-100 μM of DA, with the detection limit of 0.14 μM and quantification limit of 0.44 μM. Good selectivity overstudied bioactive compounds enables the successful and efficient application of the proposed electrode and developed an analytical procedure for the determination of dopamine in spiked urine samples.
PB  - Elsevier
T2  - Surfaces and Interfaces
T1  - CeO2-doped – domestic carbon material decorated with MWCNT as an efficient green sensing platform for electrooxidation of dopamine
VL  - 25
SP  - 101211
DO  - 10.1016/j.surfin.2021.101211
ER  - 

@article{
author = "Stanković, Dalibor and Ognjanović, Miloš and Fabián, Martin and Avdin, Vyacheslav Viktorovich and Manojlović, Dragan D. and Vranješ-Đurić, Sanja and Petković, Branka B.",
year = "2021",
abstract = "The goal of this work was to develop green electrode material that unites all advantages of domestic made, synthesized porous carbon powder and ceria dioxide nanoparticles known due to exceptional catalytic properties. Thermal decomposition of Novolac phenol-formaldehyde resin and cerium sulfate resulting in producing a high-performance CeO2 porous carbon material highly sensitive to dopamine (DA) electrooxidation. Morphological and structural characteristics of the material were determined by SEM and XRD measurements, while electrochemical characterization was performed by EIS and CV. The sensitivity of DA determination on the proposed CeO2-doped carbon material was enhanced by adding multi-wall carbon nanotubes to finally prepare a mixture for a specific carbon paste electrode (TPCeO2&MWCNT@CPE). SWV technique was used for quantification of dopamine in Britton-Robinson buffer pH 6 in the concentration range of 0.5-100 μM of DA, with the detection limit of 0.14 μM and quantification limit of 0.44 μM. Good selectivity overstudied bioactive compounds enables the successful and efficient application of the proposed electrode and developed an analytical procedure for the determination of dopamine in spiked urine samples.",
publisher = "Elsevier",
journal = "Surfaces and Interfaces",
title = "CeO2-doped – domestic carbon material decorated with MWCNT as an efficient green sensing platform for electrooxidation of dopamine",
volume = "25",
pages = "101211",
doi = "10.1016/j.surfin.2021.101211"
}

Stanković, D., Ognjanović, M., Fabián, M., Avdin, V. V., Manojlović, D. D., Vranješ-Đurić, S.,& Petković, B. B.. (2021). CeO2-doped – domestic carbon material decorated with MWCNT as an efficient green sensing platform for electrooxidation of dopamine. in Surfaces and Interfaces
Elsevier., 25, 101211.
https://doi.org/10.1016/j.surfin.2021.101211

Stanković D, Ognjanović M, Fabián M, Avdin VV, Manojlović DD, Vranješ-Đurić S, Petković BB. CeO2-doped – domestic carbon material decorated with MWCNT as an efficient green sensing platform for electrooxidation of dopamine. in Surfaces and Interfaces. 2021;25:101211.
doi:10.1016/j.surfin.2021.101211 .

Stanković, Dalibor, Ognjanović, Miloš, Fabián, Martin, Avdin, Vyacheslav Viktorovich, Manojlović, Dragan D., Vranješ-Đurić, Sanja, Petković, Branka B., "CeO2-doped – domestic carbon material decorated with MWCNT as an efficient green sensing platform for electrooxidation of dopamine" in Surfaces and Interfaces, 25 (2021):101211,
https://doi.org/10.1016/j.surfin.2021.101211 . .

TY  - JOUR
AU  - Petković, Branka B.
AU  - Ognjanović, Miloš
AU  - Antić, Bratislav
AU  - Viktorovich Avdin, Vyacheslav
AU  - Manojlović, Dragan D.
AU  - Vranješ-Đurić, Sanja
AU  - Stanković, Dalibor
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4818
AB  - The homemade, porous carbon material, thermolysis prepared from Novolac phenol-formaldehyde resin, in situ modified with Co3O4 nanoparticles and mixed with single-wall carbon nanotubes, was used in selective sensing of prominent antioxidant α-lipoic acid (LA). XRD, SEM and EIS measurements were used for characterization of material composition, structure, morphology and improved conductivity. The quantification of LA at TPCo3O4&SWCNTCPE was done by a square-wave voltammetric technique in BR buffer solution at pH 6. The linear working range was recorded from 2 to 100 μM of LA and the proposed electrode material was successfully applied in the determination of LA in dietary supplements.
PB  - Wiley
T2  - Electroanalysis
T1  - Easily Prepared Co3O4 Doped Porous Carbon Material Decorated with Single-wall Carbon Nanotubes Applied in Voltammetric Sensing of Antioxidant α-lipoic Acid
VL  - 33
IS  - 2
SP  - 446
EP  - 454
DO  - 10.1002/elan.202060290
ER  - 

@article{
author = "Petković, Branka B. and Ognjanović, Miloš and Antić, Bratislav and Viktorovich Avdin, Vyacheslav and Manojlović, Dragan D. and Vranješ-Đurić, Sanja and Stanković, Dalibor",
year = "2021",
abstract = "The homemade, porous carbon material, thermolysis prepared from Novolac phenol-formaldehyde resin, in situ modified with Co3O4 nanoparticles and mixed with single-wall carbon nanotubes, was used in selective sensing of prominent antioxidant α-lipoic acid (LA). XRD, SEM and EIS measurements were used for characterization of material composition, structure, morphology and improved conductivity. The quantification of LA at TPCo3O4&SWCNTCPE was done by a square-wave voltammetric technique in BR buffer solution at pH 6. The linear working range was recorded from 2 to 100 μM of LA and the proposed electrode material was successfully applied in the determination of LA in dietary supplements.",
publisher = "Wiley",
journal = "Electroanalysis",
title = "Easily Prepared Co3O4 Doped Porous Carbon Material Decorated with Single-wall Carbon Nanotubes Applied in Voltammetric Sensing of Antioxidant α-lipoic Acid",
volume = "33",
number = "2",
pages = "446-454",
doi = "10.1002/elan.202060290"
}

Petković, B. B., Ognjanović, M., Antić, B., Viktorovich Avdin, V., Manojlović, D. D., Vranješ-Đurić, S.,& Stanković, D.. (2021). Easily Prepared Co3O4 Doped Porous Carbon Material Decorated with Single-wall Carbon Nanotubes Applied in Voltammetric Sensing of Antioxidant α-lipoic Acid. in Electroanalysis
Wiley., 33(2), 446-454.
https://doi.org/10.1002/elan.202060290

Petković BB, Ognjanović M, Antić B, Viktorovich Avdin V, Manojlović DD, Vranješ-Đurić S, Stanković D. Easily Prepared Co3O4 Doped Porous Carbon Material Decorated with Single-wall Carbon Nanotubes Applied in Voltammetric Sensing of Antioxidant α-lipoic Acid. in Electroanalysis. 2021;33(2):446-454.
doi:10.1002/elan.202060290 .

Petković, Branka B., Ognjanović, Miloš, Antić, Bratislav, Viktorovich Avdin, Vyacheslav, Manojlović, Dragan D., Vranješ-Đurić, Sanja, Stanković, Dalibor, "Easily Prepared Co3O4 Doped Porous Carbon Material Decorated with Single-wall Carbon Nanotubes Applied in Voltammetric Sensing of Antioxidant α-lipoic Acid" in Electroanalysis, 33, no. 2 (2021):446-454,
https://doi.org/10.1002/elan.202060290 . .

TY  - JOUR
AU  - Stanković, Dalibor
AU  - Milanović, Zorana
AU  - Švorc, Ljubomir
AU  - Stanković, Vesna
AU  - Janković, Drina
AU  - Mirković, Marija D.
AU  - Vranješ-Đurić, Sanja
PY  - 2021
UR  - https://www.sciencedirect.com/science/article/pii/S0925963521000406
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4450
AB  - This work presents advanced electrochemical platform based on screen printed diamond electrode (SPDE) system for the single drop “point-of-care” testing. Proposed approach was applied for the quantification of doxorubicin hydrochloride (DOX) in biological fluids and pharmaceutical product. Using a single drop (~30 μL) of the tested solution at the electrode surface, DOX showed high electroactivity over a wide range of pHs. In these conditions, single oval shaped, well-defined and pH dependent oxidation peak was observed in the potential range from 0.5 V to 1.3 V. In the reverse scan, two cathodic peaks, were noted – around 0.3 V and – 0.5 V. Similarly, first reduction peak was pH dependent, while second one was independent in the studied range. Experimental conditions for DOX quantification were optimized and natures of the electrode reactions were investigated. Working linear range obtained for DOX detection was from 0.1 to 2.5 μM. Diffusion controlled electrode reaction reveal long life time of the proposed electrode as well high potential for practical application. Developed procedure was successfully applied for the DOX analysis in biological fluids – urine and pharmaceutical formulation. Obtained results clearly indicated that given procedure can be easily implemented for pharmaceutical control and medical analysis, in both, laboratory and field conditions.
T2  - Diamond and Related Materials
T1  - Screen printed diamond electrode as efficient “point-of-care” platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product
VL  - 113
SP  - 108277
DO  - 10.1016/j.diamond.2021.108277
ER  - 

@article{
author = "Stanković, Dalibor and Milanović, Zorana and Švorc, Ljubomir and Stanković, Vesna and Janković, Drina and Mirković, Marija D. and Vranješ-Đurić, Sanja",
year = "2021",
abstract = "This work presents advanced electrochemical platform based on screen printed diamond electrode (SPDE) system for the single drop “point-of-care” testing. Proposed approach was applied for the quantification of doxorubicin hydrochloride (DOX) in biological fluids and pharmaceutical product. Using a single drop (~30 μL) of the tested solution at the electrode surface, DOX showed high electroactivity over a wide range of pHs. In these conditions, single oval shaped, well-defined and pH dependent oxidation peak was observed in the potential range from 0.5 V to 1.3 V. In the reverse scan, two cathodic peaks, were noted – around 0.3 V and – 0.5 V. Similarly, first reduction peak was pH dependent, while second one was independent in the studied range. Experimental conditions for DOX quantification were optimized and natures of the electrode reactions were investigated. Working linear range obtained for DOX detection was from 0.1 to 2.5 μM. Diffusion controlled electrode reaction reveal long life time of the proposed electrode as well high potential for practical application. Developed procedure was successfully applied for the DOX analysis in biological fluids – urine and pharmaceutical formulation. Obtained results clearly indicated that given procedure can be easily implemented for pharmaceutical control and medical analysis, in both, laboratory and field conditions.",
journal = "Diamond and Related Materials",
title = "Screen printed diamond electrode as efficient “point-of-care” platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product",
volume = "113",
pages = "108277",
doi = "10.1016/j.diamond.2021.108277"
}

Stanković, D., Milanović, Z., Švorc, L., Stanković, V., Janković, D., Mirković, M. D.,& Vranješ-Đurić, S.. (2021). Screen printed diamond electrode as efficient “point-of-care” platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product. in Diamond and Related Materials, 113, 108277.
https://doi.org/10.1016/j.diamond.2021.108277

Stanković D, Milanović Z, Švorc L, Stanković V, Janković D, Mirković MD, Vranješ-Đurić S. Screen printed diamond electrode as efficient “point-of-care” platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product. in Diamond and Related Materials. 2021;113:108277.
doi:10.1016/j.diamond.2021.108277 .

Stanković, Dalibor, Milanović, Zorana, Švorc, Ljubomir, Stanković, Vesna, Janković, Drina, Mirković, Marija D., Vranješ-Đurić, Sanja, "Screen printed diamond electrode as efficient “point-of-care” platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product" in Diamond and Related Materials, 113 (2021):108277,
https://doi.org/10.1016/j.diamond.2021.108277 . .

TY  - JOUR
AU  - Radović, Magdalena
AU  - Mirković, Marija D.
AU  - Nikolić, Aleksandar S.
AU  - Kuraica, Milorad M.
AU  - Iskrenović, Predrag
AU  - Milanović, Zorana
AU  - Vranješ-Đurić, Sanja
AU  - Perić, Marko
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4569
AB  - Different phosphates and phosphonates have shown excellent coating ability toward magnetic nanoparticles, improving their stability and biocompatibility which enables their biomedical application. The magnetic hyperthermia efficiency of phosphates (IDP and IHP) and phosphonates (MDP and HEDP) coated Fe3O4 magnetic nanoparticles (MNPs) were evaluated in an alternating magnetic field. For a deeper understanding of hyperthermia, the behavior of investigated MNPs in the non-alternating magnetic field was monitored by measuring the transparency of the sample. To investigate their theranostic potential coated Fe3O4-MNPs were radiolabeled with radionuclide 177Lu. Phosphate coated MNPs were radiolabeled in high radiolabeling yield (> 99%) while phosphonate coated MNPs reached maximum radiolabeling yield of 78%. Regardless lower radiolabeling yield both radiolabeled phosphonate MNPs may be further purified reaching radiochemical purity of more than 95%. In vitro stabile radiolabeled nanoparticles in saline and HSA were obtained. The high heating ability of phosphates and phosphonates coated MNPs as sine qua non for efficient in vivo hyperthermia treatment and satisfactory radiolabeling yield justifies their further research in order to develop new theranostic agents. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PB  - Springer
T2  - Journal of Inorganic and Organometallic Polymers and Materials
T1  - Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles
VL  - 31
SP  - 4426
EP  - 4433
DO  - 10.1007/s10904-021-02059-1
ER  - 

@article{
author = "Radović, Magdalena and Mirković, Marija D. and Nikolić, Aleksandar S. and Kuraica, Milorad M. and Iskrenović, Predrag and Milanović, Zorana and Vranješ-Đurić, Sanja and Perić, Marko",
year = "2021",
abstract = "Different phosphates and phosphonates have shown excellent coating ability toward magnetic nanoparticles, improving their stability and biocompatibility which enables their biomedical application. The magnetic hyperthermia efficiency of phosphates (IDP and IHP) and phosphonates (MDP and HEDP) coated Fe3O4 magnetic nanoparticles (MNPs) were evaluated in an alternating magnetic field. For a deeper understanding of hyperthermia, the behavior of investigated MNPs in the non-alternating magnetic field was monitored by measuring the transparency of the sample. To investigate their theranostic potential coated Fe3O4-MNPs were radiolabeled with radionuclide 177Lu. Phosphate coated MNPs were radiolabeled in high radiolabeling yield (> 99%) while phosphonate coated MNPs reached maximum radiolabeling yield of 78%. Regardless lower radiolabeling yield both radiolabeled phosphonate MNPs may be further purified reaching radiochemical purity of more than 95%. In vitro stabile radiolabeled nanoparticles in saline and HSA were obtained. The high heating ability of phosphates and phosphonates coated MNPs as sine qua non for efficient in vivo hyperthermia treatment and satisfactory radiolabeling yield justifies their further research in order to develop new theranostic agents. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",
publisher = "Springer",
journal = "Journal of Inorganic and Organometallic Polymers and Materials",
title = "Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles",
volume = "31",
pages = "4426-4433",
doi = "10.1007/s10904-021-02059-1"
}

Radović, M., Mirković, M. D., Nikolić, A. S., Kuraica, M. M., Iskrenović, P., Milanović, Z., Vranješ-Đurić, S.,& Perić, M.. (2021). Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles. in Journal of Inorganic and Organometallic Polymers and Materials
Springer., 31, 4426-4433.
https://doi.org/10.1007/s10904-021-02059-1

Radović M, Mirković MD, Nikolić AS, Kuraica MM, Iskrenović P, Milanović Z, Vranješ-Đurić S, Perić M. Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles. in Journal of Inorganic and Organometallic Polymers and Materials. 2021;31:4426-4433.
doi:10.1007/s10904-021-02059-1 .

Radović, Magdalena, Mirković, Marija D., Nikolić, Aleksandar S., Kuraica, Milorad M., Iskrenović, Predrag, Milanović, Zorana, Vranješ-Đurić, Sanja, Perić, Marko, "Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles" in Journal of Inorganic and Organometallic Polymers and Materials, 31 (2021):4426-4433,
https://doi.org/10.1007/s10904-021-02059-1 . .

TY  - DATA
AU  - Radović, Magdalena
AU  - Mirković, Marija D.
AU  - Nikolić, Aleksandar S.
AU  - Kuraica, Milorad M.
AU  - Iskrenović, Predrag
AU  - Milanović, Zorana
AU  - Vranješ-Đurić, Sanja
AU  - Perić, Marko
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4570
PB  - Springer
T2  - Journal of Inorganic and Organometallic Polymers and Materials
T1  - Supplementary data for the article: Radović, M.; Mirković, M.; Nikolić, A. S.; Kuraica, M.; Iskrenović, P.; Milanović, Z.; Vranješ-Đurić, S.; Perić, M. Transmittance Measurements in Non-Alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles. Journal of Inorganic and Organometallic Polymers and Materials 2021. https://doi.org/10.1007/s10904-021-02059-1.
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4570
ER  - 

@misc{
author = "Radović, Magdalena and Mirković, Marija D. and Nikolić, Aleksandar S. and Kuraica, Milorad M. and Iskrenović, Predrag and Milanović, Zorana and Vranješ-Đurić, Sanja and Perić, Marko",
year = "2021",
publisher = "Springer",
journal = "Journal of Inorganic and Organometallic Polymers and Materials",
title = "Supplementary data for the article: Radović, M.; Mirković, M.; Nikolić, A. S.; Kuraica, M.; Iskrenović, P.; Milanović, Z.; Vranješ-Đurić, S.; Perić, M. Transmittance Measurements in Non-Alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles. Journal of Inorganic and Organometallic Polymers and Materials 2021. https://doi.org/10.1007/s10904-021-02059-1.",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4570"
}

Radović, M., Mirković, M. D., Nikolić, A. S., Kuraica, M. M., Iskrenović, P., Milanović, Z., Vranješ-Đurić, S.,& Perić, M.. (2021). Supplementary data for the article: Radović, M.; Mirković, M.; Nikolić, A. S.; Kuraica, M.; Iskrenović, P.; Milanović, Z.; Vranješ-Đurić, S.; Perić, M. Transmittance Measurements in Non-Alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles. Journal of Inorganic and Organometallic Polymers and Materials 2021. https://doi.org/10.1007/s10904-021-02059-1.. in Journal of Inorganic and Organometallic Polymers and Materials
Springer..
https://hdl.handle.net/21.15107/rcub_cherry_4570

Radović M, Mirković MD, Nikolić AS, Kuraica MM, Iskrenović P, Milanović Z, Vranješ-Đurić S, Perić M. Supplementary data for the article: Radović, M.; Mirković, M.; Nikolić, A. S.; Kuraica, M.; Iskrenović, P.; Milanović, Z.; Vranješ-Đurić, S.; Perić, M. Transmittance Measurements in Non-Alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles. Journal of Inorganic and Organometallic Polymers and Materials 2021. https://doi.org/10.1007/s10904-021-02059-1.. in Journal of Inorganic and Organometallic Polymers and Materials. 2021;.
https://hdl.handle.net/21.15107/rcub_cherry_4570 .

Radović, Magdalena, Mirković, Marija D., Nikolić, Aleksandar S., Kuraica, Milorad M., Iskrenović, Predrag, Milanović, Zorana, Vranješ-Đurić, Sanja, Perić, Marko, "Supplementary data for the article: Radović, M.; Mirković, M.; Nikolić, A. S.; Kuraica, M.; Iskrenović, P.; Milanović, Z.; Vranješ-Đurić, S.; Perić, M. Transmittance Measurements in Non-Alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles. Journal of Inorganic and Organometallic Polymers and Materials 2021. https://doi.org/10.1007/s10904-021-02059-1." in Journal of Inorganic and Organometallic Polymers and Materials (2021),
https://hdl.handle.net/21.15107/rcub_cherry_4570 .

TY  - JOUR
AU  - Ognjanović, Miloš
AU  - Stanković, Vesna
AU  - Knežević, Sara
AU  - Antić, Bratislav
AU  - Vranješ-Đurić, Sanja
AU  - Stanković, Dalibor
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4023
AB  - Herein, we proposed a novel approach and state-of-the-art technology for the improvement of the materials and enzyme immobilization at the electrode surface and construction of impedimetric glucose biosensor. We silanized titanium dioxide nanoparticles using (3-aminopropyl)triethoxysilane (APTES), for the preparation of cross-linked material nanoparticles, with carboxylic graphene. The silanization of titanium dioxide nanoparticles and an increase in electron shuttle was proven feasible when this composite was able to achieve about 30% higher current than non-silanized material. The proposed approach was used for the modification of the printed three-electrode system and the development of the impedimetric glucose biosensor. The material morphology and electrochemical characteristics were confirmed by spectroscopic and electrochemical methods. The present combination effectively modified the electrode surface and serve as a promising basis for the construction of Point-of-Care devices. Developed biosensor possesses wide operating linear range toward glucose detection from 50 µmol to 1000 µmol, with the limit of detection of 24 µmol. Finally, negligible interference effect and application in the real sample indicate that the proposed mechanism can be successfully applied to the assessment of glucose level in only one drop of real sample.
PB  - Elsevier
T2  - Microchemical Journal
T1  - TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor
VL  - 158
DO  - 10.1016/j.microc.2020.105150
ER  - 

@article{
author = "Ognjanović, Miloš and Stanković, Vesna and Knežević, Sara and Antić, Bratislav and Vranješ-Đurić, Sanja and Stanković, Dalibor",
year = "2020",
abstract = "Herein, we proposed a novel approach and state-of-the-art technology for the improvement of the materials and enzyme immobilization at the electrode surface and construction of impedimetric glucose biosensor. We silanized titanium dioxide nanoparticles using (3-aminopropyl)triethoxysilane (APTES), for the preparation of cross-linked material nanoparticles, with carboxylic graphene. The silanization of titanium dioxide nanoparticles and an increase in electron shuttle was proven feasible when this composite was able to achieve about 30% higher current than non-silanized material. The proposed approach was used for the modification of the printed three-electrode system and the development of the impedimetric glucose biosensor. The material morphology and electrochemical characteristics were confirmed by spectroscopic and electrochemical methods. The present combination effectively modified the electrode surface and serve as a promising basis for the construction of Point-of-Care devices. Developed biosensor possesses wide operating linear range toward glucose detection from 50 µmol to 1000 µmol, with the limit of detection of 24 µmol. Finally, negligible interference effect and application in the real sample indicate that the proposed mechanism can be successfully applied to the assessment of glucose level in only one drop of real sample.",
publisher = "Elsevier",
journal = "Microchemical Journal",
title = "TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor",
volume = "158",
doi = "10.1016/j.microc.2020.105150"
}

Ognjanović, M., Stanković, V., Knežević, S., Antić, B., Vranješ-Đurić, S.,& Stanković, D.. (2020). TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor. in Microchemical Journal
Elsevier., 158.
https://doi.org/10.1016/j.microc.2020.105150

Ognjanović M, Stanković V, Knežević S, Antić B, Vranješ-Đurić S, Stanković D. TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor. in Microchemical Journal. 2020;158.
doi:10.1016/j.microc.2020.105150 .

Ognjanović, Miloš, Stanković, Vesna, Knežević, Sara, Antić, Bratislav, Vranješ-Đurić, Sanja, Stanković, Dalibor, "TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor" in Microchemical Journal, 158 (2020),
https://doi.org/10.1016/j.microc.2020.105150 . .

TY  - JOUR
AU  - Knežević, Sara
AU  - Ognjanović, Miloš
AU  - Nedić, Nemanja
AU  - Mariano, José F.M.L.
AU  - Milanović, Zorana
AU  - Petković, Branka B.
AU  - Antić, Bratislav
AU  - Vranješ-Đurić, Sanja
AU  - Stanković, Dalibor
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3880
AB  - In order to ensure high food quality, one of the prime importance is the detection and quantification of histamine, well known marine food poison. In this work, we constructed novel electrochemical biosensor for the detection of histamine based on gold nanoparticles decorated on manganese dioxide (Au/MnO2) and used for modification of screen-printed carbon electrode (Au/MnO2@SPCE). The constructed sensor was then used for the estimation of histamine content in a single drop. Materials used in this study were synthesized and characterized using HR-TEM, XRPD and electrochemical methods. The amperometric detection method was optimized and, under selected operating parameters (supporting electrolyte pH 6, working potential of 1 V), the proposed sensor possesses linear working range from 0.3 µM to 5.1 µM, with a detection limit of 0.08 µM. The effect of selected interferences was investigated and it was found that the developed approach offers accurate, precise, selective, fast and reproducible quantification of histamine using only one drop of the sample. In the end, this work stands as a proof-of-concept of the modified electrodes and electrochemical detection as a promising and prospective approach for the applications in real-time monitoring of the food quality.
PB  - Elsevier
T2  - Microchemical Journal
T1  - A single drop histamine sensor based on AuNPs/MnO2 modified screen-printed electrode
VL  - 155
DO  - 10.1016/j.microc.2020.104778
ER  - 

@article{
author = "Knežević, Sara and Ognjanović, Miloš and Nedić, Nemanja and Mariano, José F.M.L. and Milanović, Zorana and Petković, Branka B. and Antić, Bratislav and Vranješ-Đurić, Sanja and Stanković, Dalibor",
year = "2020",
abstract = "In order to ensure high food quality, one of the prime importance is the detection and quantification of histamine, well known marine food poison. In this work, we constructed novel electrochemical biosensor for the detection of histamine based on gold nanoparticles decorated on manganese dioxide (Au/MnO2) and used for modification of screen-printed carbon electrode (Au/MnO2@SPCE). The constructed sensor was then used for the estimation of histamine content in a single drop. Materials used in this study were synthesized and characterized using HR-TEM, XRPD and electrochemical methods. The amperometric detection method was optimized and, under selected operating parameters (supporting electrolyte pH 6, working potential of 1 V), the proposed sensor possesses linear working range from 0.3 µM to 5.1 µM, with a detection limit of 0.08 µM. The effect of selected interferences was investigated and it was found that the developed approach offers accurate, precise, selective, fast and reproducible quantification of histamine using only one drop of the sample. In the end, this work stands as a proof-of-concept of the modified electrodes and electrochemical detection as a promising and prospective approach for the applications in real-time monitoring of the food quality.",
publisher = "Elsevier",
journal = "Microchemical Journal",
title = "A single drop histamine sensor based on AuNPs/MnO2 modified screen-printed electrode",
volume = "155",
doi = "10.1016/j.microc.2020.104778"
}

Knežević, S., Ognjanović, M., Nedić, N., Mariano, J. F.M.L., Milanović, Z., Petković, B. B., Antić, B., Vranješ-Đurić, S.,& Stanković, D.. (2020). A single drop histamine sensor based on AuNPs/MnO2 modified screen-printed electrode. in Microchemical Journal
Elsevier., 155.
https://doi.org/10.1016/j.microc.2020.104778

Knežević S, Ognjanović M, Nedić N, Mariano JF, Milanović Z, Petković BB, Antić B, Vranješ-Đurić S, Stanković D. A single drop histamine sensor based on AuNPs/MnO2 modified screen-printed electrode. in Microchemical Journal. 2020;155.
doi:10.1016/j.microc.2020.104778 .

Knežević, Sara, Ognjanović, Miloš, Nedić, Nemanja, Mariano, José F.M.L., Milanović, Zorana, Petković, Branka B., Antić, Bratislav, Vranješ-Đurić, Sanja, Stanković, Dalibor, "A single drop histamine sensor based on AuNPs/MnO2 modified screen-printed electrode" in Microchemical Journal, 155 (2020),
https://doi.org/10.1016/j.microc.2020.104778 . .

TY  - JOUR
AU  - Stanković, Dalibor
AU  - Ristić, Slavica M.
AU  - Vukadinović, Aleksandar
AU  - Mirković, Marija D.
AU  - Vladimirov, Sandra S.
AU  - Milanović, Zorana
AU  - Radović, Magdalena
AU  - Mijović, Milica
AU  - Stanković, Dalibor
AU  - Sabo, Tibor
AU  - Vranješ-Đurić, Sanja
AU  - Janković, Drina
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2894
AB  - It was reported that novel O,O′-diethyl-(S, S)-ethylenediamine-N,N′-di-2-(3-cyclohexyl) propanoate dihydrochloride (DE-EDCP) displayed in vitro antiproliferative activity on several human and mouse cancer cell lines, which was comparable to that of the prototypical anticancer drug cisplatin. In order to reveal its toxicity profile, acute and repeated-dose toxicity studies were performed in Naval Medical Research Institute (NMRI) Han mice. The intravenous LD 50 values of DE-EDCP were found to be 95.3 and 101.3 mg/kg body weight in female and male mice, respectively. In the subacute toxicity study, DE-EDCP was administered intravenously at the doses of 15, 25, and 40 mg/kg/day for a period of 28 days. There were no adverse effects on general condition, growth, feed and water consumption, and hematological parameters. There was a significant increase in urea and alanine aminotransferase in female mice and aspartate aminotransferase and alkaline phosphatase in both genders in 40 mg/kg/day dose-treated group. The histopathological changes confined to the liver and kidney, but in other organs were not found. Satellite group revealed that changes in the kidney and liver were less pronounced, suggesting their reversibility. Interactions with DNA could also be of importance for understanding DE-EDCP toxic side effects. Hyperchromic effect obtained with ultraviolet–visible, suggested electrostatic interactions between DE-EDCP and calf thymus DNA. The toxicity testing of DE-EDCP was conducted to predict human outcomes.
PB  - SAGE PUBLICATIONS LTD
T2  - Human and Experimental Toxicology
T1  - Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP
VL  - 38
IS  - 4
SP  - 466
EP  - 481
DO  - 10.1177/0960327118819047
ER  - 

@article{
author = "Stanković, Dalibor and Ristić, Slavica M. and Vukadinović, Aleksandar and Mirković, Marija D. and Vladimirov, Sandra S. and Milanović, Zorana and Radović, Magdalena and Mijović, Milica and Stanković, Dalibor and Sabo, Tibor and Vranješ-Đurić, Sanja and Janković, Drina",
year = "2019",
abstract = "It was reported that novel O,O′-diethyl-(S, S)-ethylenediamine-N,N′-di-2-(3-cyclohexyl) propanoate dihydrochloride (DE-EDCP) displayed in vitro antiproliferative activity on several human and mouse cancer cell lines, which was comparable to that of the prototypical anticancer drug cisplatin. In order to reveal its toxicity profile, acute and repeated-dose toxicity studies were performed in Naval Medical Research Institute (NMRI) Han mice. The intravenous LD 50 values of DE-EDCP were found to be 95.3 and 101.3 mg/kg body weight in female and male mice, respectively. In the subacute toxicity study, DE-EDCP was administered intravenously at the doses of 15, 25, and 40 mg/kg/day for a period of 28 days. There were no adverse effects on general condition, growth, feed and water consumption, and hematological parameters. There was a significant increase in urea and alanine aminotransferase in female mice and aspartate aminotransferase and alkaline phosphatase in both genders in 40 mg/kg/day dose-treated group. The histopathological changes confined to the liver and kidney, but in other organs were not found. Satellite group revealed that changes in the kidney and liver were less pronounced, suggesting their reversibility. Interactions with DNA could also be of importance for understanding DE-EDCP toxic side effects. Hyperchromic effect obtained with ultraviolet–visible, suggested electrostatic interactions between DE-EDCP and calf thymus DNA. The toxicity testing of DE-EDCP was conducted to predict human outcomes.",
publisher = "SAGE PUBLICATIONS LTD",
journal = "Human and Experimental Toxicology",
title = "Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP",
volume = "38",
number = "4",
pages = "466-481",
doi = "10.1177/0960327118819047"
}

Stanković, D., Ristić, S. M., Vukadinović, A., Mirković, M. D., Vladimirov, S. S., Milanović, Z., Radović, M., Mijović, M., Stanković, D., Sabo, T., Vranješ-Đurić, S.,& Janković, D.. (2019). Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP. in Human and Experimental Toxicology
SAGE PUBLICATIONS LTD., 38(4), 466-481.
https://doi.org/10.1177/0960327118819047

Stanković D, Ristić SM, Vukadinović A, Mirković MD, Vladimirov SS, Milanović Z, Radović M, Mijović M, Stanković D, Sabo T, Vranješ-Đurić S, Janković D. Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP. in Human and Experimental Toxicology. 2019;38(4):466-481.
doi:10.1177/0960327118819047 .

Stanković, Dalibor, Ristić, Slavica M., Vukadinović, Aleksandar, Mirković, Marija D., Vladimirov, Sandra S., Milanović, Zorana, Radović, Magdalena, Mijović, Milica, Stanković, Dalibor, Sabo, Tibor, Vranješ-Đurić, Sanja, Janković, Drina, "Toxicity study of DE-EDCP as a potential drug for cancer therapy: Toxicity profile of DE-EDCP" in Human and Experimental Toxicology, 38, no. 4 (2019):466-481,
https://doi.org/10.1177/0960327118819047 . .

TY  - JOUR
AU  - Perić, Marko
AU  - Radović, Magdalena
AU  - Mirković, Marija D.
AU  - Nikolić, Aleksandar S.
AU  - Iskrenović, Predrag
AU  - Janković, Drina
AU  - Vranješ-Đurić, Sanja
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2910
AB  - The advances in nanotechnology are directed towards the development of new theranostic agents based on magnetic nanoparticles that can be used for both cancer detection and treatment. In this study, 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles (Fe 3 O 4 -DPD MNPs) were evaluated for their theranostic application using different methods. The magnetic hyperthermia efficiency of the Fe 3 O 4 -DPD MNPs was investigated in saline solution with ionic strengths between 0.05 and 1.0 mol dm −3 . For a better understanding of hyperthermia, the behavior of Fe 3 O 4 -DPD MNPs under a non-alternating magnetic field was studied, and the transparency of the sample was measured. Furthermore, the radiotracer method using the radionuclides 99m Tc and 90 Y was applied as a reliable and powerful method for evaluating the in vivo behavior of a nanoprobe; a high radiolabeling yield (>93%), in vitro and in vivo stability of the radiolabeled nanoparticles and high heating effect were observed, thus paving the way for the possible theranostic applications of Fe 3 O 4 -DPD MNPs.
PB  - The Royal Society of Chemistry
T2  - New Journal of Chemistry
T1  - The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications
VL  - 43
IS  - 15
SP  - 5932
EP  - 5939
DO  - 10.1039/c8nj06478d
ER  - 

@article{
author = "Perić, Marko and Radović, Magdalena and Mirković, Marija D. and Nikolić, Aleksandar S. and Iskrenović, Predrag and Janković, Drina and Vranješ-Đurić, Sanja",
year = "2019",
abstract = "The advances in nanotechnology are directed towards the development of new theranostic agents based on magnetic nanoparticles that can be used for both cancer detection and treatment. In this study, 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles (Fe 3 O 4 -DPD MNPs) were evaluated for their theranostic application using different methods. The magnetic hyperthermia efficiency of the Fe 3 O 4 -DPD MNPs was investigated in saline solution with ionic strengths between 0.05 and 1.0 mol dm −3 . For a better understanding of hyperthermia, the behavior of Fe 3 O 4 -DPD MNPs under a non-alternating magnetic field was studied, and the transparency of the sample was measured. Furthermore, the radiotracer method using the radionuclides 99m Tc and 90 Y was applied as a reliable and powerful method for evaluating the in vivo behavior of a nanoprobe; a high radiolabeling yield (>93%), in vitro and in vivo stability of the radiolabeled nanoparticles and high heating effect were observed, thus paving the way for the possible theranostic applications of Fe 3 O 4 -DPD MNPs.",
publisher = "The Royal Society of Chemistry",
journal = "New Journal of Chemistry",
title = "The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications",
volume = "43",
number = "15",
pages = "5932-5939",
doi = "10.1039/c8nj06478d"
}

Perić, M., Radović, M., Mirković, M. D., Nikolić, A. S., Iskrenović, P., Janković, D.,& Vranješ-Đurić, S.. (2019). The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications. in New Journal of Chemistry
The Royal Society of Chemistry., 43(15), 5932-5939.
https://doi.org/10.1039/c8nj06478d

Perić M, Radović M, Mirković MD, Nikolić AS, Iskrenović P, Janković D, Vranješ-Đurić S. The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications. in New Journal of Chemistry. 2019;43(15):5932-5939.
doi:10.1039/c8nj06478d .

Perić, Marko, Radović, Magdalena, Mirković, Marija D., Nikolić, Aleksandar S., Iskrenović, Predrag, Janković, Drina, Vranješ-Đurić, Sanja, "The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications" in New Journal of Chemistry, 43, no. 15 (2019):5932-5939,
https://doi.org/10.1039/c8nj06478d . .

TY  - JOUR
AU  - Perić, Marko
AU  - Radović, Magdalena
AU  - Mirković, Marija D.
AU  - Nikolić, Aleksandar S.
AU  - Iskrenović, Predrag
AU  - Janković, Drina
AU  - Vranješ-Đurić, Sanja
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2911
AB  - The advances in nanotechnology are directed towards the development of new theranostic agents based on magnetic nanoparticles that can be used for both cancer detection and treatment. In this study, 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles (Fe 3 O 4 -DPD MNPs) were evaluated for their theranostic application using different methods. The magnetic hyperthermia efficiency of the Fe 3 O 4 -DPD MNPs was investigated in saline solution with ionic strengths between 0.05 and 1.0 mol dm −3 . For a better understanding of hyperthermia, the behavior of Fe 3 O 4 -DPD MNPs under a non-alternating magnetic field was studied, and the transparency of the sample was measured. Furthermore, the radiotracer method using the radionuclides 99m Tc and 90 Y was applied as a reliable and powerful method for evaluating the in vivo behavior of a nanoprobe; a high radiolabeling yield (>93%), in vitro and in vivo stability of the radiolabeled nanoparticles and high heating effect were observed, thus paving the way for the possible theranostic applications of Fe 3 O 4 -DPD MNPs.
PB  - The Royal Society of Chemistry
T2  - New Journal of Chemistry
T1  - The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications
VL  - 43
IS  - 15
SP  - 5932
EP  - 5939
DO  - 10.1039/c8nj06478d
ER  - 

@article{
author = "Perić, Marko and Radović, Magdalena and Mirković, Marija D. and Nikolić, Aleksandar S. and Iskrenović, Predrag and Janković, Drina and Vranješ-Đurić, Sanja",
year = "2019",
abstract = "The advances in nanotechnology are directed towards the development of new theranostic agents based on magnetic nanoparticles that can be used for both cancer detection and treatment. In this study, 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles (Fe 3 O 4 -DPD MNPs) were evaluated for their theranostic application using different methods. The magnetic hyperthermia efficiency of the Fe 3 O 4 -DPD MNPs was investigated in saline solution with ionic strengths between 0.05 and 1.0 mol dm −3 . For a better understanding of hyperthermia, the behavior of Fe 3 O 4 -DPD MNPs under a non-alternating magnetic field was studied, and the transparency of the sample was measured. Furthermore, the radiotracer method using the radionuclides 99m Tc and 90 Y was applied as a reliable and powerful method for evaluating the in vivo behavior of a nanoprobe; a high radiolabeling yield (>93%), in vitro and in vivo stability of the radiolabeled nanoparticles and high heating effect were observed, thus paving the way for the possible theranostic applications of Fe 3 O 4 -DPD MNPs.",
publisher = "The Royal Society of Chemistry",
journal = "New Journal of Chemistry",
title = "The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications",
volume = "43",
number = "15",
pages = "5932-5939",
doi = "10.1039/c8nj06478d"
}

Perić, M., Radović, M., Mirković, M. D., Nikolić, A. S., Iskrenović, P., Janković, D.,& Vranješ-Đurić, S.. (2019). The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications. in New Journal of Chemistry
The Royal Society of Chemistry., 43(15), 5932-5939.
https://doi.org/10.1039/c8nj06478d

Perić M, Radović M, Mirković MD, Nikolić AS, Iskrenović P, Janković D, Vranješ-Đurić S. The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications. in New Journal of Chemistry. 2019;43(15):5932-5939.
doi:10.1039/c8nj06478d .

Perić, Marko, Radović, Magdalena, Mirković, Marija D., Nikolić, Aleksandar S., Iskrenović, Predrag, Janković, Drina, Vranješ-Đurić, Sanja, "The analysis of 2,3-dicarboxypropane-1,1-diphosphonic acid-coated magnetite nanoparticles under an external magnetic field and their radiolabeling for possible theranostic applications" in New Journal of Chemistry, 43, no. 15 (2019):5932-5939,
https://doi.org/10.1039/c8nj06478d . .

TY  - JOUR
AU  - Antić, Bratislav
AU  - Bošković, Marko
AU  - Nikodinović-Runić, Jasmina
AU  - Ming, Yue
AU  - Zhang, Hongguo
AU  - Bozin, Emil S.
AU  - Janković, Drina
AU  - Spasojević, Vojislav
AU  - Vranješ-Đurić, Sanja
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3086
AB  - Magnetic nanoparticles (MNPs) are of immense interest for diagnostic and therapeutic applications in medicine. Design and development of new iron oxide-based MNPs for such applications is of rather limited breadth without reliable and sensitive methods to determine their levels in body tissues. Commonly used methods, such as ICP, are quite problematic, due to the inability to decipher the origin of the detected iron, i.e. whether it originates from the MNPs or endogenous from tissues and bodily fluids. One of the approaches to overcome this problem and to increase reliability of tracing MNPs is to partially substitute iron ions in the MNPs with Er. Here, we report on the development of citric add coated (Fe,Er)(3)O-4 nanopartides and characterization of their physico-chemical and biological properties by utilization of various complementary approaches. The synthesized MNPs had a narrow (6-7 nm) size distribution, as consistently seen in atomic pair distribution function, transmission electron microscopy, and DC magnetization measurements. The particles were found to be superparamagnetic, with a pronounced maximum in measured zero-field cooled magnetization at around 90 K. Reduction in saturation magnetization due to incorporation of 1.7% Er3+ into the Fe3O4 matrix was clearly observed. From the biological standpoint, citric acid coated (Fe,Er)(3)O-4 NPs were found to induce low toxicity both in human cell fibroblasts and in zebrafish (Danio rerio) embryos. Biodistribution pattern of the MNPs after intravenous administration in healthy Wistar rats was followed by the radiotracer method, revealing that Y-90-labeled MNPs were predominantly found in liver (7533% ID), followed by lungs (16.70% ID) and spleen (2.83% ID). Quantitative agreement with these observations was obtained by ICP-MS elemental analysis using Er as the detected tracer. Based on the favorable physical, chemical and biological characteristics, citric add coated (Fe,Er)(3)O-4 MNPs could be further considered for the potential application as a diagnostic and/or therapeutic agent. This work also demonstrates that combined application of these techniques is a promising tool for studies of pharmacokinetics of the new MNPs in complex biological systems.
PB  - Elsevier Science Bv, Amsterdam
T2  - Materials Science and Engineering C
T1  - Complementary approaches for the evaluation of biocompatibility of 90Y-labeled superparamagnetic citric acid (Fe,Er)3O4 coated nanoparticles
VL  - 75
SP  - 157
EP  - 164
DO  - 10.1016/j.msec.2017.02.023
ER  - 

@article{
author = "Antić, Bratislav and Bošković, Marko and Nikodinović-Runić, Jasmina and Ming, Yue and Zhang, Hongguo and Bozin, Emil S. and Janković, Drina and Spasojević, Vojislav and Vranješ-Đurić, Sanja",
year = "2017",
abstract = "Magnetic nanoparticles (MNPs) are of immense interest for diagnostic and therapeutic applications in medicine. Design and development of new iron oxide-based MNPs for such applications is of rather limited breadth without reliable and sensitive methods to determine their levels in body tissues. Commonly used methods, such as ICP, are quite problematic, due to the inability to decipher the origin of the detected iron, i.e. whether it originates from the MNPs or endogenous from tissues and bodily fluids. One of the approaches to overcome this problem and to increase reliability of tracing MNPs is to partially substitute iron ions in the MNPs with Er. Here, we report on the development of citric add coated (Fe,Er)(3)O-4 nanopartides and characterization of their physico-chemical and biological properties by utilization of various complementary approaches. The synthesized MNPs had a narrow (6-7 nm) size distribution, as consistently seen in atomic pair distribution function, transmission electron microscopy, and DC magnetization measurements. The particles were found to be superparamagnetic, with a pronounced maximum in measured zero-field cooled magnetization at around 90 K. Reduction in saturation magnetization due to incorporation of 1.7% Er3+ into the Fe3O4 matrix was clearly observed. From the biological standpoint, citric acid coated (Fe,Er)(3)O-4 NPs were found to induce low toxicity both in human cell fibroblasts and in zebrafish (Danio rerio) embryos. Biodistribution pattern of the MNPs after intravenous administration in healthy Wistar rats was followed by the radiotracer method, revealing that Y-90-labeled MNPs were predominantly found in liver (7533% ID), followed by lungs (16.70% ID) and spleen (2.83% ID). Quantitative agreement with these observations was obtained by ICP-MS elemental analysis using Er as the detected tracer. Based on the favorable physical, chemical and biological characteristics, citric add coated (Fe,Er)(3)O-4 MNPs could be further considered for the potential application as a diagnostic and/or therapeutic agent. This work also demonstrates that combined application of these techniques is a promising tool for studies of pharmacokinetics of the new MNPs in complex biological systems.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Materials Science and Engineering C",
title = "Complementary approaches for the evaluation of biocompatibility of 90Y-labeled superparamagnetic citric acid (Fe,Er)3O4 coated nanoparticles",
volume = "75",
pages = "157-164",
doi = "10.1016/j.msec.2017.02.023"
}

Antić, B., Bošković, M., Nikodinović-Runić, J., Ming, Y., Zhang, H., Bozin, E. S., Janković, D., Spasojević, V.,& Vranješ-Đurić, S.. (2017). Complementary approaches for the evaluation of biocompatibility of 90Y-labeled superparamagnetic citric acid (Fe,Er)3O4 coated nanoparticles. in Materials Science and Engineering C
Elsevier Science Bv, Amsterdam., 75, 157-164.
https://doi.org/10.1016/j.msec.2017.02.023

Antić B, Bošković M, Nikodinović-Runić J, Ming Y, Zhang H, Bozin ES, Janković D, Spasojević V, Vranješ-Đurić S. Complementary approaches for the evaluation of biocompatibility of 90Y-labeled superparamagnetic citric acid (Fe,Er)3O4 coated nanoparticles. in Materials Science and Engineering C. 2017;75:157-164.
doi:10.1016/j.msec.2017.02.023 .

Antić, Bratislav, Bošković, Marko, Nikodinović-Runić, Jasmina, Ming, Yue, Zhang, Hongguo, Bozin, Emil S., Janković, Drina, Spasojević, Vojislav, Vranješ-Đurić, Sanja, "Complementary approaches for the evaluation of biocompatibility of 90Y-labeled superparamagnetic citric acid (Fe,Er)3O4 coated nanoparticles" in Materials Science and Engineering C, 75 (2017):157-164,
https://doi.org/10.1016/j.msec.2017.02.023 . .

TY  - DATA
AU  - Antić, Bratislav
AU  - Bošković, Marko
AU  - Nikodinović-Runić, Jasmina
AU  - Ming, Yue
AU  - Zhang, Hongguo
AU  - Bozin, Emil S.
AU  - Janković, Drina
AU  - Spasojević, Vojislav
AU  - Vranješ-Đurić, Sanja
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3087
PB  - Elsevier Science Bv, Amsterdam
T2  - Materials Science and Engineering C
T1  - Supplementary data for article: Antic, B.; Boskovic, M.; Nikodinovic-Runic, J.; Ming, Y.; Zhang, H.; Bozin, E. S.; Janković, D.; Spasojevic, V.; Vranjes-Djuric, S. Complementary Approaches for the Evaluation of Biocompatibility of 90Y-Labeled Superparamagnetic Citric Acid (Fe,Er)3O4 Coated Nanoparticles. Materials Science and Engineering C 2017, 75, 157–164. https://doi.org/10.1016/j.msec.2017.02.023
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3087
ER  - 

@misc{
author = "Antić, Bratislav and Bošković, Marko and Nikodinović-Runić, Jasmina and Ming, Yue and Zhang, Hongguo and Bozin, Emil S. and Janković, Drina and Spasojević, Vojislav and Vranješ-Đurić, Sanja",
year = "2017",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Materials Science and Engineering C",
title = "Supplementary data for article: Antic, B.; Boskovic, M.; Nikodinovic-Runic, J.; Ming, Y.; Zhang, H.; Bozin, E. S.; Janković, D.; Spasojevic, V.; Vranjes-Djuric, S. Complementary Approaches for the Evaluation of Biocompatibility of 90Y-Labeled Superparamagnetic Citric Acid (Fe,Er)3O4 Coated Nanoparticles. Materials Science and Engineering C 2017, 75, 157–164. https://doi.org/10.1016/j.msec.2017.02.023",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3087"
}

Antić, B., Bošković, M., Nikodinović-Runić, J., Ming, Y., Zhang, H., Bozin, E. S., Janković, D., Spasojević, V.,& Vranješ-Đurić, S.. (2017). Supplementary data for article: Antic, B.; Boskovic, M.; Nikodinovic-Runic, J.; Ming, Y.; Zhang, H.; Bozin, E. S.; Janković, D.; Spasojevic, V.; Vranjes-Djuric, S. Complementary Approaches for the Evaluation of Biocompatibility of 90Y-Labeled Superparamagnetic Citric Acid (Fe,Er)3O4 Coated Nanoparticles. Materials Science and Engineering C 2017, 75, 157–164. https://doi.org/10.1016/j.msec.2017.02.023. in Materials Science and Engineering C
Elsevier Science Bv, Amsterdam..
https://hdl.handle.net/21.15107/rcub_cherry_3087

Antić B, Bošković M, Nikodinović-Runić J, Ming Y, Zhang H, Bozin ES, Janković D, Spasojević V, Vranješ-Đurić S. Supplementary data for article: Antic, B.; Boskovic, M.; Nikodinovic-Runic, J.; Ming, Y.; Zhang, H.; Bozin, E. S.; Janković, D.; Spasojevic, V.; Vranjes-Djuric, S. Complementary Approaches for the Evaluation of Biocompatibility of 90Y-Labeled Superparamagnetic Citric Acid (Fe,Er)3O4 Coated Nanoparticles. Materials Science and Engineering C 2017, 75, 157–164. https://doi.org/10.1016/j.msec.2017.02.023. in Materials Science and Engineering C. 2017;.
https://hdl.handle.net/21.15107/rcub_cherry_3087 .

Antić, Bratislav, Bošković, Marko, Nikodinović-Runić, Jasmina, Ming, Yue, Zhang, Hongguo, Bozin, Emil S., Janković, Drina, Spasojević, Vojislav, Vranješ-Đurić, Sanja, "Supplementary data for article: Antic, B.; Boskovic, M.; Nikodinovic-Runic, J.; Ming, Y.; Zhang, H.; Bozin, E. S.; Janković, D.; Spasojevic, V.; Vranjes-Djuric, S. Complementary Approaches for the Evaluation of Biocompatibility of 90Y-Labeled Superparamagnetic Citric Acid (Fe,Er)3O4 Coated Nanoparticles. Materials Science and Engineering C 2017, 75, 157–164. https://doi.org/10.1016/j.msec.2017.02.023" in Materials Science and Engineering C (2017),
https://hdl.handle.net/21.15107/rcub_cherry_3087 .

TY  - JOUR
AU  - Antić, Bratislav
AU  - Bošković, Marko
AU  - Nikodinović-Runić, Jasmina
AU  - Ming, Yue
AU  - Zhang, Hongguo
AU  - Bozin, Emil S.
AU  - Janković, Drina
AU  - Spasojević, Vojislav
AU  - Vranješ-Đurić, Sanja
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2453
AB  - Magnetic nanoparticles (MNPs) are of immense interest for diagnostic and therapeutic applications in medicine. Design and development of new iron oxide-based MNPs for such applications is of rather limited breadth without reliable and sensitive methods to determine their levels in body tissues. Commonly used methods, such as ICP, are quite problematic, due to the inability to decipher the origin of the detected iron, i.e. whether it originates from the MNPs or endogenous from tissues and bodily fluids. One of the approaches to overcome this problem and to increase reliability of tracing MNPs is to partially substitute iron ions in the MNPs with Er. Here, we report on the development of citric add coated (Fe,Er)(3)O-4 nanopartides and characterization of their physico-chemical and biological properties by utilization of various complementary approaches. The synthesized MNPs had a narrow (6-7 nm) size distribution, as consistently seen in atomic pair distribution function, transmission electron microscopy, and DC magnetization measurements. The particles were found to be superparamagnetic, with a pronounced maximum in measured zero-field cooled magnetization at around 90 K. Reduction in saturation magnetization due to incorporation of 1.7% Er3+ into the Fe3O4 matrix was clearly observed. From the biological standpoint, citric acid coated (Fe,Er)(3)O-4 NPs were found to induce low toxicity both in human cell fibroblasts and in zebrafish (Danio rerio) embryos. Biodistribution pattern of the MNPs after intravenous administration in healthy Wistar rats was followed by the radiotracer method, revealing that Y-90-labeled MNPs were predominantly found in liver (7533% ID), followed by lungs (16.70% ID) and spleen (2.83% ID). Quantitative agreement with these observations was obtained by ICP-MS elemental analysis using Er as the detected tracer. Based on the favorable physical, chemical and biological characteristics, citric add coated (Fe,Er)(3)O-4 MNPs could be further considered for the potential application as a diagnostic and/or therapeutic agent. This work also demonstrates that combined application of these techniques is a promising tool for studies of pharmacokinetics of the new MNPs in complex biological systems.
PB  - Elsevier Science Bv, Amsterdam
T2  - Materials Science and Engineering. C: Materials for Biological Applications
T1  - Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles
VL  - 75
SP  - 157
EP  - 164
DO  - 10.1016/j.msec.2017.02.023
ER  - 

@article{
author = "Antić, Bratislav and Bošković, Marko and Nikodinović-Runić, Jasmina and Ming, Yue and Zhang, Hongguo and Bozin, Emil S. and Janković, Drina and Spasojević, Vojislav and Vranješ-Đurić, Sanja",
year = "2017",
abstract = "Magnetic nanoparticles (MNPs) are of immense interest for diagnostic and therapeutic applications in medicine. Design and development of new iron oxide-based MNPs for such applications is of rather limited breadth without reliable and sensitive methods to determine their levels in body tissues. Commonly used methods, such as ICP, are quite problematic, due to the inability to decipher the origin of the detected iron, i.e. whether it originates from the MNPs or endogenous from tissues and bodily fluids. One of the approaches to overcome this problem and to increase reliability of tracing MNPs is to partially substitute iron ions in the MNPs with Er. Here, we report on the development of citric add coated (Fe,Er)(3)O-4 nanopartides and characterization of their physico-chemical and biological properties by utilization of various complementary approaches. The synthesized MNPs had a narrow (6-7 nm) size distribution, as consistently seen in atomic pair distribution function, transmission electron microscopy, and DC magnetization measurements. The particles were found to be superparamagnetic, with a pronounced maximum in measured zero-field cooled magnetization at around 90 K. Reduction in saturation magnetization due to incorporation of 1.7% Er3+ into the Fe3O4 matrix was clearly observed. From the biological standpoint, citric acid coated (Fe,Er)(3)O-4 NPs were found to induce low toxicity both in human cell fibroblasts and in zebrafish (Danio rerio) embryos. Biodistribution pattern of the MNPs after intravenous administration in healthy Wistar rats was followed by the radiotracer method, revealing that Y-90-labeled MNPs were predominantly found in liver (7533% ID), followed by lungs (16.70% ID) and spleen (2.83% ID). Quantitative agreement with these observations was obtained by ICP-MS elemental analysis using Er as the detected tracer. Based on the favorable physical, chemical and biological characteristics, citric add coated (Fe,Er)(3)O-4 MNPs could be further considered for the potential application as a diagnostic and/or therapeutic agent. This work also demonstrates that combined application of these techniques is a promising tool for studies of pharmacokinetics of the new MNPs in complex biological systems.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Materials Science and Engineering. C: Materials for Biological Applications",
title = "Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles",
volume = "75",
pages = "157-164",
doi = "10.1016/j.msec.2017.02.023"
}

Antić, B., Bošković, M., Nikodinović-Runić, J., Ming, Y., Zhang, H., Bozin, E. S., Janković, D., Spasojević, V.,& Vranješ-Đurić, S.. (2017). Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles. in Materials Science and Engineering. C: Materials for Biological Applications
Elsevier Science Bv, Amsterdam., 75, 157-164.
https://doi.org/10.1016/j.msec.2017.02.023

Antić B, Bošković M, Nikodinović-Runić J, Ming Y, Zhang H, Bozin ES, Janković D, Spasojević V, Vranješ-Đurić S. Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles. in Materials Science and Engineering. C: Materials for Biological Applications. 2017;75:157-164.
doi:10.1016/j.msec.2017.02.023 .

Antić, Bratislav, Bošković, Marko, Nikodinović-Runić, Jasmina, Ming, Yue, Zhang, Hongguo, Bozin, Emil S., Janković, Drina, Spasojević, Vojislav, Vranješ-Đurić, Sanja, "Complementary approaches for the evaluation of biocompatibility of Y-90-labeled superparamagnetic citric acid (Fe,Er)(3)O-4 coated nanoparticles" in Materials Science and Engineering. C: Materials for Biological Applications, 75 (2017):157-164,
https://doi.org/10.1016/j.msec.2017.02.023 . .

TY  - JOUR
AU  - Lakić, Mladen
AU  - Sabo, Ljubica
AU  - Ristić, Slavica
AU  - Savić, Aleksandar
AU  - Petričević, Saša
AU  - Nikolić, Nadežda
AU  - Vukadinović, Aleksandar
AU  - Janković, Drina
AU  - Sabo, Tibor
AU  - Vranješ-Đurić, Sanja
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2045
AB  - The extensive development of radiopharmaceuticals towards early tumour detection and treatment has increased the demand for new ligands with higher tumour selectivity. Research has been done on the potential of the novel O,O'-diethylethylenediamine-N,N'-di-3-propanoate (L) ligand as a radionuclide vehicle for tumour targeting. Under alkaline conditions, L hydrolyses and produces half ester ligand (L') and diacid ligand (L"), with characteristic donor atom array N, N, O. Ligand L was successfully labelled with Tc-99m at pH=9 by coordination with the octahedral fac-[Tc-99m(CO)(3)(H2O)(3)](+) intermediate, forming the main radioproduct fac-[(TcL)-Tc-99m'(CO)(3)] (Tc1). The Tc-99m complex showed a low lipophilic character (log P = 0.48) and low binding affinity to human serum albumin (2.51 +/- 0.48%). In vitro stability studies in saline and human plasma, as well as challenge studies with cysteine and histidine, revealed high stability of the complex during 24 h. Biodistribution studies of Tc1 in female C57BL/6 mice bearing B16/F1 melanoma metastases showed significant tumour uptake: 9.81 +/- 1.19% ID g(-1) in the liver, 5.87 +/- 0.54% ID g(-1) in the lungs and 3.17 +/- 0.33% ID g(-1) in the ovary at 30 min post-injection. Favourable physicochemical properties, satisfactory in vitro/in vivo stability and biodistribution profile in the experimental metastatic melanoma model indicate the possible application of the radiolabelled ligand in tumour diagnosis. Copyright (C) 2015 John Wiley & Sons, Ltd.
PB  - Wiley, Hoboken
T2  - Applied Organometallic Chemistry
T1  - Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O '-diethylethylenediamine-N,N '-di-3-propanoate as potential tumour diagnostic agent
VL  - 30
IS  - 2
SP  - 81
EP  - 88
DO  - 10.1002/aoc.3401
ER  - 

@article{
author = "Lakić, Mladen and Sabo, Ljubica and Ristić, Slavica and Savić, Aleksandar and Petričević, Saša and Nikolić, Nadežda and Vukadinović, Aleksandar and Janković, Drina and Sabo, Tibor and Vranješ-Đurić, Sanja",
year = "2016",
abstract = "The extensive development of radiopharmaceuticals towards early tumour detection and treatment has increased the demand for new ligands with higher tumour selectivity. Research has been done on the potential of the novel O,O'-diethylethylenediamine-N,N'-di-3-propanoate (L) ligand as a radionuclide vehicle for tumour targeting. Under alkaline conditions, L hydrolyses and produces half ester ligand (L') and diacid ligand (L"), with characteristic donor atom array N, N, O. Ligand L was successfully labelled with Tc-99m at pH=9 by coordination with the octahedral fac-[Tc-99m(CO)(3)(H2O)(3)](+) intermediate, forming the main radioproduct fac-[(TcL)-Tc-99m'(CO)(3)] (Tc1). The Tc-99m complex showed a low lipophilic character (log P = 0.48) and low binding affinity to human serum albumin (2.51 +/- 0.48%). In vitro stability studies in saline and human plasma, as well as challenge studies with cysteine and histidine, revealed high stability of the complex during 24 h. Biodistribution studies of Tc1 in female C57BL/6 mice bearing B16/F1 melanoma metastases showed significant tumour uptake: 9.81 +/- 1.19% ID g(-1) in the liver, 5.87 +/- 0.54% ID g(-1) in the lungs and 3.17 +/- 0.33% ID g(-1) in the ovary at 30 min post-injection. Favourable physicochemical properties, satisfactory in vitro/in vivo stability and biodistribution profile in the experimental metastatic melanoma model indicate the possible application of the radiolabelled ligand in tumour diagnosis. Copyright (C) 2015 John Wiley & Sons, Ltd.",
publisher = "Wiley, Hoboken",
journal = "Applied Organometallic Chemistry",
title = "Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O '-diethylethylenediamine-N,N '-di-3-propanoate as potential tumour diagnostic agent",
volume = "30",
number = "2",
pages = "81-88",
doi = "10.1002/aoc.3401"
}

Lakić, M., Sabo, L., Ristić, S., Savić, A., Petričević, S., Nikolić, N., Vukadinović, A., Janković, D., Sabo, T.,& Vranješ-Đurić, S.. (2016). Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O '-diethylethylenediamine-N,N '-di-3-propanoate as potential tumour diagnostic agent. in Applied Organometallic Chemistry
Wiley, Hoboken., 30(2), 81-88.
https://doi.org/10.1002/aoc.3401

Lakić M, Sabo L, Ristić S, Savić A, Petričević S, Nikolić N, Vukadinović A, Janković D, Sabo T, Vranješ-Đurić S. Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O '-diethylethylenediamine-N,N '-di-3-propanoate as potential tumour diagnostic agent. in Applied Organometallic Chemistry. 2016;30(2):81-88.
doi:10.1002/aoc.3401 .

Lakić, Mladen, Sabo, Ljubica, Ristić, Slavica, Savić, Aleksandar, Petričević, Saša, Nikolić, Nadežda, Vukadinović, Aleksandar, Janković, Drina, Sabo, Tibor, Vranješ-Đurić, Sanja, "Synthesis and biological evaluation of Tc-99m tricarbonyl complex of O,O '-diethylethylenediamine-N,N '-di-3-propanoate as potential tumour diagnostic agent" in Applied Organometallic Chemistry, 30, no. 2 (2016):81-88,
https://doi.org/10.1002/aoc.3401 . .