TY  - JOUR
AU  - Đorđević, Dragana S.
AU  - Milovanović, Jelena
AU  - Jurisević, Milena
AU  - Stojanović, Bojana
AU  - Cvetković, Olga
AU  - Pergal, Marija V.
AU  - Ristanović, Elizabeta
AU  - Vojvodić, Danilo
AU  - Simić, Miloš
AU  - Manojlović, Dragan D.
AU  - Milovanović, Marija
AU  - Arsenijević, Nebojša
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3858
AB  - Copper serves as a limiting factor for multiple steps of tumour progression, including angiogenesis, growth and metastasis. High levels of copper have been found in a wide spectrum of human cancers. Antitumour activities of copper-chelating drugs have been reported in animal models. Organosulfur compounds (diallyl sulfide, DAS; diallyl disulfide, DADS; S-ethylcysteine, SEC; N-acetylcysteine, NAC) derived from garlic exhibit marked copper-chelating activity. We analysed a mixture of fifteen n-propyl polysulfides (DPPS) for potential antitumour activity against several murine tumour cell lines, including colon carcinoma (CT26), mammary carcinoma (4T1) and melanoma cell lines (B16F10), and compared the effects with the antiproliferative effect in highly proliferative murine mesenchymal stem cells (mMSCs). The effects of the mixture of n-propyl polysulfides (100%) on cell viability were determined using MTT assays. Cell apoptosis was analysed using Annexin V-FITC/PI assays.

The results of the MTT assays indicate that this standardized mixture of n-propyl polysulfides has a strong, dose-dependent cytotoxic effect against all three of the tested tumour cell lines (CT26, 4T1, B16F10). The cytotoxic effect of the n-propyl polysulfide mixture against the CT26 and B16F10 cell lines was much stronger than that of cisplatin and was significantly weaker in mMSCs, which are non-cancerous and highly proliferative cells, than in cancer cells. Flow cytometric analysis of CT26 and 4T1 cells revealed that apoptosis was not the dominant mechanism of cell death induced by the n-propyl polysulfide mixture. The n-propyl polysulfide mixture exerted highly cytotoxic activity against murine colon carcinoma and melanoma cell lines, but its antiproliferative activity against mMSCs was significantly lower than that of cisplatin.
T2  - Serbian Journal of Experimental and Clinical Research
T1  - Antitumour effect of a mixture of n-propyl polysulfides In vitro
VL  - 20
IS  - 4
SP  - 295
EP  - 300
DO  - 10.1515/sjecr-2017-0069
ER  - 

@article{
author = "Đorđević, Dragana S. and Milovanović, Jelena and Jurisević, Milena and Stojanović, Bojana and Cvetković, Olga and Pergal, Marija V. and Ristanović, Elizabeta and Vojvodić, Danilo and Simić, Miloš and Manojlović, Dragan D. and Milovanović, Marija and Arsenijević, Nebojša",
year = "2019",
abstract = "Copper serves as a limiting factor for multiple steps of tumour progression, including angiogenesis, growth and metastasis. High levels of copper have been found in a wide spectrum of human cancers. Antitumour activities of copper-chelating drugs have been reported in animal models. Organosulfur compounds (diallyl sulfide, DAS; diallyl disulfide, DADS; S-ethylcysteine, SEC; N-acetylcysteine, NAC) derived from garlic exhibit marked copper-chelating activity. We analysed a mixture of fifteen n-propyl polysulfides (DPPS) for potential antitumour activity against several murine tumour cell lines, including colon carcinoma (CT26), mammary carcinoma (4T1) and melanoma cell lines (B16F10), and compared the effects with the antiproliferative effect in highly proliferative murine mesenchymal stem cells (mMSCs). The effects of the mixture of n-propyl polysulfides (100%) on cell viability were determined using MTT assays. Cell apoptosis was analysed using Annexin V-FITC/PI assays.

The results of the MTT assays indicate that this standardized mixture of n-propyl polysulfides has a strong, dose-dependent cytotoxic effect against all three of the tested tumour cell lines (CT26, 4T1, B16F10). The cytotoxic effect of the n-propyl polysulfide mixture against the CT26 and B16F10 cell lines was much stronger than that of cisplatin and was significantly weaker in mMSCs, which are non-cancerous and highly proliferative cells, than in cancer cells. Flow cytometric analysis of CT26 and 4T1 cells revealed that apoptosis was not the dominant mechanism of cell death induced by the n-propyl polysulfide mixture. The n-propyl polysulfide mixture exerted highly cytotoxic activity against murine colon carcinoma and melanoma cell lines, but its antiproliferative activity against mMSCs was significantly lower than that of cisplatin.",
journal = "Serbian Journal of Experimental and Clinical Research",
title = "Antitumour effect of a mixture of n-propyl polysulfides In vitro",
volume = "20",
number = "4",
pages = "295-300",
doi = "10.1515/sjecr-2017-0069"
}

Đorđević, D. S., Milovanović, J., Jurisević, M., Stojanović, B., Cvetković, O., Pergal, M. V., Ristanović, E., Vojvodić, D., Simić, M., Manojlović, D. D., Milovanović, M.,& Arsenijević, N.. (2019). Antitumour effect of a mixture of n-propyl polysulfides In vitro. in Serbian Journal of Experimental and Clinical Research, 20(4), 295-300.
https://doi.org/10.1515/sjecr-2017-0069

Đorđević DS, Milovanović J, Jurisević M, Stojanović B, Cvetković O, Pergal MV, Ristanović E, Vojvodić D, Simić M, Manojlović DD, Milovanović M, Arsenijević N. Antitumour effect of a mixture of n-propyl polysulfides In vitro. in Serbian Journal of Experimental and Clinical Research. 2019;20(4):295-300.
doi:10.1515/sjecr-2017-0069 .

Đorđević, Dragana S., Milovanović, Jelena, Jurisević, Milena, Stojanović, Bojana, Cvetković, Olga, Pergal, Marija V., Ristanović, Elizabeta, Vojvodić, Danilo, Simić, Miloš, Manojlović, Dragan D., Milovanović, Marija, Arsenijević, Nebojša, "Antitumour effect of a mixture of n-propyl polysulfides In vitro" in Serbian Journal of Experimental and Clinical Research, 20, no. 4 (2019):295-300,
https://doi.org/10.1515/sjecr-2017-0069 . .

TY  - JOUR
AU  - Vukelić, Gordana
AU  - Cvetković, Olga
AU  - Gržetić, Ivan
AU  - Simić, Miloš
AU  - Miodragović, Zoran
AU  - Lazić, Lazar
AU  - Zarić, Miroljub
AU  - Pešić, Aleksandar
AU  - Vulić, Predrag J.
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2159
AB  - The aim of this work is to assess damage to the City of Belgrade caused by the unfavorable weather condition of hail due to the absence of anti-hail defense of the city, and to argumentatively point out the necessity of introducing new technical-technological systems for preventing the effects of adverse weather conditions. The results are based on the direct correlation-analyses of two real unfavorable weather events and the estimated financial damage caused by these events. The overall calculation also takes into account financial investments (new financial model) necessary to establish two essentially different systems for anti-hail protection. The damage caused by the hail on the territory of the City of Belgrade and the financial investment in anti-hail protection to reduce it are empirically established for the first time. It is shown how the damage could be transformed to profit, as the financial investment in anti-hail protection is lower than the damage that hail can cause.
PB  - Mdpi, Basel
T2  - Sustainability
T1  - Anti-Hail Protection-Assessment of Financial Effects on the Territory of Belgrade
VL  - 10
IS  - 4
DO  - 10.3390/su10041239
ER  - 

@article{
author = "Vukelić, Gordana and Cvetković, Olga and Gržetić, Ivan and Simić, Miloš and Miodragović, Zoran and Lazić, Lazar and Zarić, Miroljub and Pešić, Aleksandar and Vulić, Predrag J.",
year = "2018",
abstract = "The aim of this work is to assess damage to the City of Belgrade caused by the unfavorable weather condition of hail due to the absence of anti-hail defense of the city, and to argumentatively point out the necessity of introducing new technical-technological systems for preventing the effects of adverse weather conditions. The results are based on the direct correlation-analyses of two real unfavorable weather events and the estimated financial damage caused by these events. The overall calculation also takes into account financial investments (new financial model) necessary to establish two essentially different systems for anti-hail protection. The damage caused by the hail on the territory of the City of Belgrade and the financial investment in anti-hail protection to reduce it are empirically established for the first time. It is shown how the damage could be transformed to profit, as the financial investment in anti-hail protection is lower than the damage that hail can cause.",
publisher = "Mdpi, Basel",
journal = "Sustainability",
title = "Anti-Hail Protection-Assessment of Financial Effects on the Territory of Belgrade",
volume = "10",
number = "4",
doi = "10.3390/su10041239"
}

Vukelić, G., Cvetković, O., Gržetić, I., Simić, M., Miodragović, Z., Lazić, L., Zarić, M., Pešić, A.,& Vulić, P. J.. (2018). Anti-Hail Protection-Assessment of Financial Effects on the Territory of Belgrade. in Sustainability
Mdpi, Basel., 10(4).
https://doi.org/10.3390/su10041239

Vukelić G, Cvetković O, Gržetić I, Simić M, Miodragović Z, Lazić L, Zarić M, Pešić A, Vulić PJ. Anti-Hail Protection-Assessment of Financial Effects on the Territory of Belgrade. in Sustainability. 2018;10(4).
doi:10.3390/su10041239 .

Vukelić, Gordana, Cvetković, Olga, Gržetić, Ivan, Simić, Miloš, Miodragović, Zoran, Lazić, Lazar, Zarić, Miroljub, Pešić, Aleksandar, Vulić, Predrag J., "Anti-Hail Protection-Assessment of Financial Effects on the Territory of Belgrade" in Sustainability, 10, no. 4 (2018),
https://doi.org/10.3390/su10041239 . .

TY  - JOUR
AU  - Dimitrijevic, R.
AU  - Cvetković, Olga
AU  - Miodragović, Zoran
AU  - Simić, Miloš

AU  - Manojlović, Dragan D.
AU  - Jovic, V.
PY  - 2013
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1460
AB  - The Ag nano-structured thin films prepared on flat glass substrates have been studied. The ball-like silver nanoparticles have been synthesized in large quantity by using a modified method of hydrolytic decomposition of silver complexes with amino types ligands formed in ethanol aqueous solution. SEM analysis revealed that Ag nanoparticles are all sphere shaped with bimodal size (40 and 70 nm) distribution. The results of XRD powder pattern examination show that Ag nanoparticles are pure phase, well crystallized. The unit cell dimensions measured on synthesized Ag nano films show small but frequent contraction in comparison to Ag metal standard.
PB  - Technical Faculty, Bor-Serbia, Bor
T2  - Journal of mining and metallurgy, Section B: Metallurgy
T1  - Sem/Edx and Xrd Characterization of Silver Nanocrystalline Thin Film Prepared from  Organometallic Solution Precursor
VL  - 49
IS  - 1
SP  - 91
EP  - 95
DO  - 10.2298/JMMB120111041D
ER  - 

@article{
author = "Dimitrijevic, R. and Cvetković, Olga and Miodragović, Zoran and Simić, Miloš
 and Manojlović, Dragan D. and Jovic, V.",
year = "2013",
abstract = "The Ag nano-structured thin films prepared on flat glass substrates have been studied. The ball-like silver nanoparticles have been synthesized in large quantity by using a modified method of hydrolytic decomposition of silver complexes with amino types ligands formed in ethanol aqueous solution. SEM analysis revealed that Ag nanoparticles are all sphere shaped with bimodal size (40 and 70 nm) distribution. The results of XRD powder pattern examination show that Ag nanoparticles are pure phase, well crystallized. The unit cell dimensions measured on synthesized Ag nano films show small but frequent contraction in comparison to Ag metal standard.",
publisher = "Technical Faculty, Bor-Serbia, Bor",
journal = "Journal of mining and metallurgy, Section B: Metallurgy",
title = "Sem/Edx and Xrd Characterization of Silver Nanocrystalline Thin Film Prepared from  Organometallic Solution Precursor",
volume = "49",
number = "1",
pages = "91-95",
doi = "10.2298/JMMB120111041D"
}

Dimitrijevic, R., Cvetković, O., Miodragović, Z., Simić, M., Manojlović, D. D.,& Jovic, V.. (2013). Sem/Edx and Xrd Characterization of Silver Nanocrystalline Thin Film Prepared from  Organometallic Solution Precursor. in Journal of mining and metallurgy, Section B: Metallurgy
Technical Faculty, Bor-Serbia, Bor., 49(1), 91-95.
https://doi.org/10.2298/JMMB120111041D

Dimitrijevic R, Cvetković O, Miodragović Z, Simić M, Manojlović DD, Jovic V. Sem/Edx and Xrd Characterization of Silver Nanocrystalline Thin Film Prepared from  Organometallic Solution Precursor. in Journal of mining and metallurgy, Section B: Metallurgy. 2013;49(1):91-95.
doi:10.2298/JMMB120111041D .

Dimitrijevic, R., Cvetković, Olga, Miodragović, Zoran, Simić, Miloš
, Manojlović, Dragan D., Jovic, V., "Sem/Edx and Xrd Characterization of Silver Nanocrystalline Thin Film Prepared from  Organometallic Solution Precursor" in Journal of mining and metallurgy, Section B: Metallurgy, 49, no. 1 (2013):91-95,
https://doi.org/10.2298/JMMB120111041D . .

TY  - JOUR
AU  - Prodanović, Radivoje
AU  - Simić, Miloš
AU  - Vujčić, Zoran
PY  - 2003
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/163
AB  - Periodate oxidized invertase was immobilized by adsorption on sepiolite. The obtained immobilized enzyme was more resistant to washing out by concentrated salt solution. and had an eight times higher half-life at 60 degreesC than adsorbed native invertase. In packed bed reactor 50%, conversion of 500 g/dm(3) sucrose at 40 degreesC and a flow rate of 1 bv/h was achieved. The specific productivity of the immobilized invertase was 0.187 kg/dm(3)/h.
AB  - Perjodatno oksidovana invertaza je imobilizovana adsorpcijom na sepiolitu. Dobijeni imobilizovani enzim je bio rezistentniji na ispiranje koncentrovanim rastvorima soli i imao je osam puta veći poluživot na 60 ºC od adsorbovane nativne invertaze. U protočnom cevastom reaktoru dobili smo 50 % konverziju rastvora saharoze koncentracije 500 g/dm3 na 40 ºC i pri protoku od 1 bv/h. Specifična produktivnost imobilizovane invertaze je bila 0,187 kg/dm3/h.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Immobilization of periodate oxidized invertase by adsorption on sepiolite
T1  - Imobilizacija perjodatno oksidovane invertaze adsorpcijom na sepiolitu
VL  - 68
IS  - 11
SP  - 819
EP  - 824
DO  - 10.2298/JSC0311819P
ER  - 

@article{
author = "Prodanović, Radivoje and Simić, Miloš and Vujčić, Zoran",
year = "2003",
abstract = "Periodate oxidized invertase was immobilized by adsorption on sepiolite. The obtained immobilized enzyme was more resistant to washing out by concentrated salt solution. and had an eight times higher half-life at 60 degreesC than adsorbed native invertase. In packed bed reactor 50%, conversion of 500 g/dm(3) sucrose at 40 degreesC and a flow rate of 1 bv/h was achieved. The specific productivity of the immobilized invertase was 0.187 kg/dm(3)/h., Perjodatno oksidovana invertaza je imobilizovana adsorpcijom na sepiolitu. Dobijeni imobilizovani enzim je bio rezistentniji na ispiranje koncentrovanim rastvorima soli i imao je osam puta veći poluživot na 60 ºC od adsorbovane nativne invertaze. U protočnom cevastom reaktoru dobili smo 50 % konverziju rastvora saharoze koncentracije 500 g/dm3 na 40 ºC i pri protoku od 1 bv/h. Specifična produktivnost imobilizovane invertaze je bila 0,187 kg/dm3/h.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Immobilization of periodate oxidized invertase by adsorption on sepiolite, Imobilizacija perjodatno oksidovane invertaze adsorpcijom na sepiolitu",
volume = "68",
number = "11",
pages = "819-824",
doi = "10.2298/JSC0311819P"
}

Prodanović, R., Simić, M.,& Vujčić, Z.. (2003). Immobilization of periodate oxidized invertase by adsorption on sepiolite. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 68(11), 819-824.
https://doi.org/10.2298/JSC0311819P

Prodanović R, Simić M, Vujčić Z. Immobilization of periodate oxidized invertase by adsorption on sepiolite. in Journal of the Serbian Chemical Society. 2003;68(11):819-824.
doi:10.2298/JSC0311819P .

Prodanović, Radivoje, Simić, Miloš, Vujčić, Zoran, "Immobilization of periodate oxidized invertase by adsorption on sepiolite" in Journal of the Serbian Chemical Society, 68, no. 11 (2003):819-824,
https://doi.org/10.2298/JSC0311819P . .