TY  - JOUR
AU  - Božić, Bojana
AU  - Korać, Jelena
AU  - Stanković, Dalibor
AU  - Stanić, Marina
AU  - Popović-Bijelić, Ana
AU  - Pristov-Bogdanović, Jelena
AU  - Spasojević, Ivan
AU  - Bajčetić, Milica
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2570
AB  - Toxic effects of unconjugated bilirubin (BR) in neonatal hyperbilirubinemia have been related to redox and/or coordinate interactions with Cu2+. However, the development and mechanisms of such interactions at physiological pH have not been resolved. This study shows that BR reduces Cu2+ to Cu1+ in 1:1 stoichiometry. Apparently, BR undergoes degradation, i.e. BR and Cu2+ do not form stable complexes. The binding of Cu2+ to inorganic phosphates, liposomal phosphate groups, or to chelating drug penicillamine, impedes redox interactions with BR. Cu1+ undergoes spontaneous oxidation by O-2 resulting in hydrogen peroxide accumulation and hydroxyl radical production. In relation to this, copper and BR induced synergistic oxidative/damaging effects on erythrocytes membrane, which were alleviated by penicillamine. The production of reactive oxygen species by BR and copper represents a plausible cause of BR toxic effects and cell damage in hyperbilirubinemia. Further examination of therapeutic potentials of copper chelators in the treatment of severe neonatal hyperbilirubinemia is needed.
PB  - Elsevier Ireland Ltd, Clare
T2  - Chemico-biological Interactions
T1  - Mechanisms of redox interactions of bilirubin with copper and the effects of penicillamine
VL  - 278
SP  - 129
EP  - 134
DO  - 10.1016/j.cbi.2017.10.022
ER  - 

@article{
author = "Božić, Bojana and Korać, Jelena and Stanković, Dalibor and Stanić, Marina and Popović-Bijelić, Ana and Pristov-Bogdanović, Jelena and Spasojević, Ivan and Bajčetić, Milica",
year = "2017",
abstract = "Toxic effects of unconjugated bilirubin (BR) in neonatal hyperbilirubinemia have been related to redox and/or coordinate interactions with Cu2+. However, the development and mechanisms of such interactions at physiological pH have not been resolved. This study shows that BR reduces Cu2+ to Cu1+ in 1:1 stoichiometry. Apparently, BR undergoes degradation, i.e. BR and Cu2+ do not form stable complexes. The binding of Cu2+ to inorganic phosphates, liposomal phosphate groups, or to chelating drug penicillamine, impedes redox interactions with BR. Cu1+ undergoes spontaneous oxidation by O-2 resulting in hydrogen peroxide accumulation and hydroxyl radical production. In relation to this, copper and BR induced synergistic oxidative/damaging effects on erythrocytes membrane, which were alleviated by penicillamine. The production of reactive oxygen species by BR and copper represents a plausible cause of BR toxic effects and cell damage in hyperbilirubinemia. Further examination of therapeutic potentials of copper chelators in the treatment of severe neonatal hyperbilirubinemia is needed.",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Chemico-biological Interactions",
title = "Mechanisms of redox interactions of bilirubin with copper and the effects of penicillamine",
volume = "278",
pages = "129-134",
doi = "10.1016/j.cbi.2017.10.022"
}

Božić, B., Korać, J., Stanković, D., Stanić, M., Popović-Bijelić, A., Pristov-Bogdanović, J., Spasojević, I.,& Bajčetić, M.. (2017). Mechanisms of redox interactions of bilirubin with copper and the effects of penicillamine. in Chemico-biological Interactions
Elsevier Ireland Ltd, Clare., 278, 129-134.
https://doi.org/10.1016/j.cbi.2017.10.022

Božić B, Korać J, Stanković D, Stanić M, Popović-Bijelić A, Pristov-Bogdanović J, Spasojević I, Bajčetić M. Mechanisms of redox interactions of bilirubin with copper and the effects of penicillamine. in Chemico-biological Interactions. 2017;278:129-134.
doi:10.1016/j.cbi.2017.10.022 .

Božić, Bojana, Korać, Jelena, Stanković, Dalibor, Stanić, Marina, Popović-Bijelić, Ana, Pristov-Bogdanović, Jelena, Spasojević, Ivan, Bajčetić, Milica, "Mechanisms of redox interactions of bilirubin with copper and the effects of penicillamine" in Chemico-biological Interactions, 278 (2017):129-134,
https://doi.org/10.1016/j.cbi.2017.10.022 . .

TY  - JOUR
AU  - Božić, Bojana
AU  - Tasic, S
AU  - Matović, Radomir
AU  - Saičić, Radomir
AU  - Dunjic, B
PY  - 2005
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/749
AB  - Novel type of crosslinkable polymeric photoinitiators with hyperbranched architecture were synthesized and characterized. This type of UV curable hyperbranched urethane acrylates utilizes xanthate groups for photoinitiation and controlled crosslinking. A series of polymers were synthesized with different types of functionalization by varying type of the hydroxyl alkyl (meta)acrylates. Obtained polymers have low viscosities and high molecular weights. Glass transition temperatures of crosslinked samples were surprisingly high for their chemical compositions.
PB  - Amer Chemical Soc, Washington
T2  - ACS Symposium Series / American Chemical Society
T1  - New hyperbranched urethane acrylates
VL  - 916
SP  - 201
EP  - 214
UR  - https://hdl.handle.net/21.15107/rcub_cherry_749
ER  - 

@article{
author = "Božić, Bojana and Tasic, S and Matović, Radomir and Saičić, Radomir and Dunjic, B",
year = "2005",
abstract = "Novel type of crosslinkable polymeric photoinitiators with hyperbranched architecture were synthesized and characterized. This type of UV curable hyperbranched urethane acrylates utilizes xanthate groups for photoinitiation and controlled crosslinking. A series of polymers were synthesized with different types of functionalization by varying type of the hydroxyl alkyl (meta)acrylates. Obtained polymers have low viscosities and high molecular weights. Glass transition temperatures of crosslinked samples were surprisingly high for their chemical compositions.",
publisher = "Amer Chemical Soc, Washington",
journal = "ACS Symposium Series / American Chemical Society",
title = "New hyperbranched urethane acrylates",
volume = "916",
pages = "201-214",
url = "https://hdl.handle.net/21.15107/rcub_cherry_749"
}

Božić, B., Tasic, S., Matović, R., Saičić, R.,& Dunjic, B.. (2005). New hyperbranched urethane acrylates. in ACS Symposium Series / American Chemical Society
Amer Chemical Soc, Washington., 916, 201-214.
https://hdl.handle.net/21.15107/rcub_cherry_749

Božić B, Tasic S, Matović R, Saičić R, Dunjic B. New hyperbranched urethane acrylates. in ACS Symposium Series / American Chemical Society. 2005;916:201-214.
https://hdl.handle.net/21.15107/rcub_cherry_749 .

Božić, Bojana, Tasic, S, Matović, Radomir, Saičić, Radomir, Dunjic, B, "New hyperbranched urethane acrylates" in ACS Symposium Series / American Chemical Society, 916 (2005):201-214,
https://hdl.handle.net/21.15107/rcub_cherry_749 .

TY  - JOUR
AU  - Prodanović, Radivoje
AU  - Milosavic, N
AU  - Sladić, Dušan
AU  - Zlatović, Mario
AU  - Božić, Bojana
AU  - Ćirković-Veličković, Tanja
AU  - Vujčić, Zoran
PY  - 2005
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/728
AB  - Hydroquinone alpha-isomaltoside and hydroquinone alpha-glucoside were synthesized by transglucosylation in an aqueous system with baker's yeast alpha-glucosidase from hydroquinone and maltose as a glucosyl donor. Only one phenolic group was glucosylated, with alpha-selectivity, and the nature of the reaction products was governed by the concentration of hydroquinone. The optimal conditions for synthesis of glycosides were 9 mM hydroquinone and 1.5 M maltose in a 100 mM sodium citrate/phosphate buffer at pH 5.0 and 30 degrees C for 20 h. Under these conditions both hydroquinone alpha-glycosides were obtained in nearly equimolar amounts with a total molar yield of 28% with respect to hydroquinone and a total glycoside concentration of 1 mg/mL in the reaction mixture. (c) 2005 Elsevier B.V. All rights reserved.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Molecular Catalysis. B: Enzymatic
T1  - Transglucosylation of hydroquinone catalysed by alpha-glucosidase from baker's yeast
VL  - 35
IS  - 4-6
SP  - 142
EP  - 146
DO  - 10.1016/j.molcatb.2005.06.011
ER  - 

@article{
author = "Prodanović, Radivoje and Milosavic, N and Sladić, Dušan and Zlatović, Mario and Božić, Bojana and Ćirković-Veličković, Tanja and Vujčić, Zoran",
year = "2005",
abstract = "Hydroquinone alpha-isomaltoside and hydroquinone alpha-glucoside were synthesized by transglucosylation in an aqueous system with baker's yeast alpha-glucosidase from hydroquinone and maltose as a glucosyl donor. Only one phenolic group was glucosylated, with alpha-selectivity, and the nature of the reaction products was governed by the concentration of hydroquinone. The optimal conditions for synthesis of glycosides were 9 mM hydroquinone and 1.5 M maltose in a 100 mM sodium citrate/phosphate buffer at pH 5.0 and 30 degrees C for 20 h. Under these conditions both hydroquinone alpha-glycosides were obtained in nearly equimolar amounts with a total molar yield of 28% with respect to hydroquinone and a total glycoside concentration of 1 mg/mL in the reaction mixture. (c) 2005 Elsevier B.V. All rights reserved.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Molecular Catalysis. B: Enzymatic",
title = "Transglucosylation of hydroquinone catalysed by alpha-glucosidase from baker's yeast",
volume = "35",
number = "4-6",
pages = "142-146",
doi = "10.1016/j.molcatb.2005.06.011"
}

Prodanović, R., Milosavic, N., Sladić, D., Zlatović, M., Božić, B., Ćirković-Veličković, T.,& Vujčić, Z.. (2005). Transglucosylation of hydroquinone catalysed by alpha-glucosidase from baker's yeast. in Journal of Molecular Catalysis. B: Enzymatic
Elsevier Science Bv, Amsterdam., 35(4-6), 142-146.
https://doi.org/10.1016/j.molcatb.2005.06.011

Prodanović R, Milosavic N, Sladić D, Zlatović M, Božić B, Ćirković-Veličković T, Vujčić Z. Transglucosylation of hydroquinone catalysed by alpha-glucosidase from baker's yeast. in Journal of Molecular Catalysis. B: Enzymatic. 2005;35(4-6):142-146.
doi:10.1016/j.molcatb.2005.06.011 .

Prodanović, Radivoje, Milosavic, N, Sladić, Dušan, Zlatović, Mario, Božić, Bojana, Ćirković-Veličković, Tanja, Vujčić, Zoran, "Transglucosylation of hydroquinone catalysed by alpha-glucosidase from baker's yeast" in Journal of Molecular Catalysis. B: Enzymatic, 35, no. 4-6 (2005):142-146,
https://doi.org/10.1016/j.molcatb.2005.06.011 . .