TY  - JOUR
AU  - Ćilerdžić, Jasmina
AU  - Sofrenić, Ivana V.
AU  - Tešević, Vele
AU  - Brčeski, Ilija
AU  - Duletić-Laušević, Sonja
AU  - Vukojević, Jelena
AU  - Stajić, Mirjana
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2153
AB  - Various neurodegenerative diseases are the main challenges to the modern medicine and there is a great need for novel, natural, neuroprotective agents. Ganoderma lucidum is a well-known medicinal mushroom, which health benefits have been confirmed by numerous studies. As demand for its basidiocarps is increased and traditional cultivation on hardwoods is not environmentally friendly and economically justified, finding of alternative substrates is necessary. The aim of the study was to assess the effect of alternative cultivation substrates on the chemical profile of G.lucidum basidiocarps and their capacity to inhibit acetylcholinesterase and tyrosinase, which higher activity is directly associated with neurodegenerative processes. Extracts of basidiocarps cultivated on alternative substrates, especially on clear wheat straw, showed significantly higher inhibition capacities than extracts of commercially-grown ones. These extracts were considerably different chemically from commercial basidiocarps extracts and even nine new compounds were isolated from them. Our results suggest that cultivation substrate greatly affect the chemical profile and neuroprotective capacity of obtained basidiocarps and wheat straw is a promising cultivation substrate.
PB  - Wiley-V C H Verlag Gmbh, Weinheim
T2  - Chemistry and Biodiversity
T1  - Neuroprotective Potential and Chemical Profile of Alternatively Cultivated Ganoderma lucidum Basidiocarps
VL  - 15
IS  - 5
DO  - 10.1002/cbdv.201800036
ER  - 

@article{
author = "Ćilerdžić, Jasmina and Sofrenić, Ivana V. and Tešević, Vele and Brčeski, Ilija and Duletić-Laušević, Sonja and Vukojević, Jelena and Stajić, Mirjana",
year = "2018",
abstract = "Various neurodegenerative diseases are the main challenges to the modern medicine and there is a great need for novel, natural, neuroprotective agents. Ganoderma lucidum is a well-known medicinal mushroom, which health benefits have been confirmed by numerous studies. As demand for its basidiocarps is increased and traditional cultivation on hardwoods is not environmentally friendly and economically justified, finding of alternative substrates is necessary. The aim of the study was to assess the effect of alternative cultivation substrates on the chemical profile of G.lucidum basidiocarps and their capacity to inhibit acetylcholinesterase and tyrosinase, which higher activity is directly associated with neurodegenerative processes. Extracts of basidiocarps cultivated on alternative substrates, especially on clear wheat straw, showed significantly higher inhibition capacities than extracts of commercially-grown ones. These extracts were considerably different chemically from commercial basidiocarps extracts and even nine new compounds were isolated from them. Our results suggest that cultivation substrate greatly affect the chemical profile and neuroprotective capacity of obtained basidiocarps and wheat straw is a promising cultivation substrate.",
publisher = "Wiley-V C H Verlag Gmbh, Weinheim",
journal = "Chemistry and Biodiversity",
title = "Neuroprotective Potential and Chemical Profile of Alternatively Cultivated Ganoderma lucidum Basidiocarps",
volume = "15",
number = "5",
doi = "10.1002/cbdv.201800036"
}

Ćilerdžić, J., Sofrenić, I. V., Tešević, V., Brčeski, I., Duletić-Laušević, S., Vukojević, J.,& Stajić, M.. (2018). Neuroprotective Potential and Chemical Profile of Alternatively Cultivated Ganoderma lucidum Basidiocarps. in Chemistry and Biodiversity
Wiley-V C H Verlag Gmbh, Weinheim., 15(5).
https://doi.org/10.1002/cbdv.201800036

Ćilerdžić J, Sofrenić IV, Tešević V, Brčeski I, Duletić-Laušević S, Vukojević J, Stajić M. Neuroprotective Potential and Chemical Profile of Alternatively Cultivated Ganoderma lucidum Basidiocarps. in Chemistry and Biodiversity. 2018;15(5).
doi:10.1002/cbdv.201800036 .

Ćilerdžić, Jasmina, Sofrenić, Ivana V., Tešević, Vele, Brčeski, Ilija, Duletić-Laušević, Sonja, Vukojević, Jelena, Stajić, Mirjana, "Neuroprotective Potential and Chemical Profile of Alternatively Cultivated Ganoderma lucidum Basidiocarps" in Chemistry and Biodiversity, 15, no. 5 (2018),
https://doi.org/10.1002/cbdv.201800036 . .

TY  - JOUR
AU  - Galić, Milica
AU  - Ćilerdžić, Jasmina
AU  - Vukojević, Jelena
AU  - Stajić, Mirjana
AU  - Brčeski, Ilija
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/357
AB  - For the last several years, there is an increasing research interest for lignocellulosic biomass because of its renewable nature. Wheat straw, as one of the most abundant plant wastes, could potentially be transformed into various high valued products (food, feed, paper, biofuel). Micromycetes play an important role in lignocellulose conversion owing to their powerfull enzymatic system. They posses different potentials to synthetise lignocelullolytic enzymes and degrade biomass. Therefore, the objectives of this study were determination of Mn-oxidising peroxidases and laccases activities and extent of wheat straw depolymerisation during solid-state fermentation by selected micromycetes species/strains. The highest Mn-dependent-and Mn-independent peroxidases activities were noted in Clonostachys rosea BEOFB 1610m on day 14 of cultivation (210.23 and 303.03 U l–1, respectively), while Alternaria sp. BEOFB 202m was the unique producer of laccase which maximum activity (1558.59 U l–1) was observed after 7 days of wheat straw fermentation. After 21 days of wheat straw depolymerisation, the highest level of lignin degradation was caused by C. rosea BEOFB 1610m (13.67%), while Alternaria sp. BEOFB 202m was the most efficient hemicellulose and cellulose degrader (38.1 and 29.8%, respectively). These data demonstrate that studied fungal species/strains could potentially be used in various biotechnological processes for the plant raw materials transformation. © 2018, Scibulcom Ltd. All rights reserved.
T2  - Journal of Environmental Protection and Ecology
T1  - Potential of selected micromycetes for wheat straw degradation
VL  - 19
IS  - 3
SP  - 1116
EP  - 1122
UR  - https://hdl.handle.net/21.15107/rcub_cherry_357
ER  - 

@article{
author = "Galić, Milica and Ćilerdžić, Jasmina and Vukojević, Jelena and Stajić, Mirjana and Brčeski, Ilija",
year = "2018",
abstract = "For the last several years, there is an increasing research interest for lignocellulosic biomass because of its renewable nature. Wheat straw, as one of the most abundant plant wastes, could potentially be transformed into various high valued products (food, feed, paper, biofuel). Micromycetes play an important role in lignocellulose conversion owing to their powerfull enzymatic system. They posses different potentials to synthetise lignocelullolytic enzymes and degrade biomass. Therefore, the objectives of this study were determination of Mn-oxidising peroxidases and laccases activities and extent of wheat straw depolymerisation during solid-state fermentation by selected micromycetes species/strains. The highest Mn-dependent-and Mn-independent peroxidases activities were noted in Clonostachys rosea BEOFB 1610m on day 14 of cultivation (210.23 and 303.03 U l–1, respectively), while Alternaria sp. BEOFB 202m was the unique producer of laccase which maximum activity (1558.59 U l–1) was observed after 7 days of wheat straw fermentation. After 21 days of wheat straw depolymerisation, the highest level of lignin degradation was caused by C. rosea BEOFB 1610m (13.67%), while Alternaria sp. BEOFB 202m was the most efficient hemicellulose and cellulose degrader (38.1 and 29.8%, respectively). These data demonstrate that studied fungal species/strains could potentially be used in various biotechnological processes for the plant raw materials transformation. © 2018, Scibulcom Ltd. All rights reserved.",
journal = "Journal of Environmental Protection and Ecology",
title = "Potential of selected micromycetes for wheat straw degradation",
volume = "19",
number = "3",
pages = "1116-1122",
url = "https://hdl.handle.net/21.15107/rcub_cherry_357"
}

Galić, M., Ćilerdžić, J., Vukojević, J., Stajić, M.,& Brčeski, I.. (2018). Potential of selected micromycetes for wheat straw degradation. in Journal of Environmental Protection and Ecology, 19(3), 1116-1122.
https://hdl.handle.net/21.15107/rcub_cherry_357

Galić M, Ćilerdžić J, Vukojević J, Stajić M, Brčeski I. Potential of selected micromycetes for wheat straw degradation. in Journal of Environmental Protection and Ecology. 2018;19(3):1116-1122.
https://hdl.handle.net/21.15107/rcub_cherry_357 .

Galić, Milica, Ćilerdžić, Jasmina, Vukojević, Jelena, Stajić, Mirjana, Brčeski, Ilija, "Potential of selected micromycetes for wheat straw degradation" in Journal of Environmental Protection and Ecology, 19, no. 3 (2018):1116-1122,
https://hdl.handle.net/21.15107/rcub_cherry_357 .

TY  - JOUR
AU  - Ćilerdžić, Jasmina
AU  - Galić, Milica
AU  - Ivanović, Žarko
AU  - Brčeski, Ilija
AU  - Vukojević, Jelena
AU  - Stajić, Mirjana
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/346
AB  - Biological pretreatment of the lignocellulosic residues, in which white-rot fungi have a crucial role, has many advantages compared to the chemical, physical, and physico-chemical methods of delignification and therefore attracts increasing scientific attention. Regarding the fact that properties and capacities of the ligninolytic enzymes of Daedaleopsis spp. are still unknown, the aim of this study was to research how nitrogen sources and inducers affect the potential of Daedaleopsis confragosa and Daedaleopsis tricolor to degrade cherry sawdust. NH4NO3, (NH4)2SO4, and peptone were tested as nitrogen sources, while veratryl alcohol, p-anisidine, vanillic acid, and phenylmethylsulfonyl fluoride were the studied inducers. As Mn-dependent peroxidase and laccase were the leader enzymes and cherry sawdust/peptone medium the best stimulator of their activities, the effect of inducers on delignification potential of these species was studied during fermentation of that substrate. Veratryl alcohol was the best stimulator of laccase and phenylmethylsulfonyl fluoride of Mn-dependent peroxidase activity (27,610.0 and 1338.4 U/L, respectively). These inducers also increased cherry sawdust delignification selectivity, particularly in D. tricolor in the presence of phenylmethylsulfonyl fluoride (lignin:hemicellulose:cellulose = 32.1%:0.9%:11.7%). Owing to the presented results, studied species could have an important role in the phase of lignocellulose pretreatment in various biotechnological processes. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.
T2  - Applied Biochemistry and Biotechnology
T1  - Stimulation of Wood Degradation by Daedaleopsis confragosa and D. tricolor
DO  - 10.1007/s12010-018-2884-2
ER  - 

@article{
author = "Ćilerdžić, Jasmina and Galić, Milica and Ivanović, Žarko and Brčeski, Ilija and Vukojević, Jelena and Stajić, Mirjana",
year = "2018",
abstract = "Biological pretreatment of the lignocellulosic residues, in which white-rot fungi have a crucial role, has many advantages compared to the chemical, physical, and physico-chemical methods of delignification and therefore attracts increasing scientific attention. Regarding the fact that properties and capacities of the ligninolytic enzymes of Daedaleopsis spp. are still unknown, the aim of this study was to research how nitrogen sources and inducers affect the potential of Daedaleopsis confragosa and Daedaleopsis tricolor to degrade cherry sawdust. NH4NO3, (NH4)2SO4, and peptone were tested as nitrogen sources, while veratryl alcohol, p-anisidine, vanillic acid, and phenylmethylsulfonyl fluoride were the studied inducers. As Mn-dependent peroxidase and laccase were the leader enzymes and cherry sawdust/peptone medium the best stimulator of their activities, the effect of inducers on delignification potential of these species was studied during fermentation of that substrate. Veratryl alcohol was the best stimulator of laccase and phenylmethylsulfonyl fluoride of Mn-dependent peroxidase activity (27,610.0 and 1338.4 U/L, respectively). These inducers also increased cherry sawdust delignification selectivity, particularly in D. tricolor in the presence of phenylmethylsulfonyl fluoride (lignin:hemicellulose:cellulose = 32.1%:0.9%:11.7%). Owing to the presented results, studied species could have an important role in the phase of lignocellulose pretreatment in various biotechnological processes. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.",
journal = "Applied Biochemistry and Biotechnology",
title = "Stimulation of Wood Degradation by Daedaleopsis confragosa and D. tricolor",
doi = "10.1007/s12010-018-2884-2"
}

Ćilerdžić, J., Galić, M., Ivanović, Ž., Brčeski, I., Vukojević, J.,& Stajić, M.. (2018). Stimulation of Wood Degradation by Daedaleopsis confragosa and D. tricolor. in Applied Biochemistry and Biotechnology.
https://doi.org/10.1007/s12010-018-2884-2

Ćilerdžić J, Galić M, Ivanović Ž, Brčeski I, Vukojević J, Stajić M. Stimulation of Wood Degradation by Daedaleopsis confragosa and D. tricolor. in Applied Biochemistry and Biotechnology. 2018;.
doi:10.1007/s12010-018-2884-2 .

Ćilerdžić, Jasmina, Galić, Milica, Ivanović, Žarko, Brčeski, Ilija, Vukojević, Jelena, Stajić, Mirjana, "Stimulation of Wood Degradation by Daedaleopsis confragosa and D. tricolor" in Applied Biochemistry and Biotechnology (2018),
https://doi.org/10.1007/s12010-018-2884-2 . .

TY  - JOUR
AU  - Stajić, Mirjana
AU  - Knezevic, A.
AU  - Vukojević, Jelena
AU  - Ćilerdžić, Jasmina
AU  - Brčeski, Ilija
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2073
AB  - Plant raw materials could be potential sources for fibre production and this biomass could be also transformed in valued food, feed, energy sources (biofuels), and paper pulp in the processes where fungi take the major role. Effectiveness of these processes depends on capacity of the fungal species but also on the presence of trace elements which can also remarkably modulate the enzyme activity and to affect biodegradation processes. Pleurotus ostreatus HAI 493 produced ligninolytic enzymes during solid-state fermentation of grapevine sawdust with significant variability in the activity level depending on presence of Fe, Zn, or Se. Enzyme activities in trace element enriched media showed increasing of laccase activity and decreasing of Mn-oxidising peroxidase activity. The highest enlargement of laccase activity (65.9%) was noted after 10 days of cultivation in the presence of Na2SeO4. The highest inhibitory level of Mn-dependent peroxidase activity (59.6%) was noted in the presence of Na2SeO4.
PB  - Scibulcom Ltd, Sofia
T2  - Journal of Environmental Protection and Ecology
T1  - Trace Elements Influence on Grapevine Degradation by Pleurotus Ostreatus
VL  - 18
IS  - 4
SP  - 1498
EP  - 1504
UR  - https://hdl.handle.net/21.15107/rcub_cherry_2073
ER  - 

@article{
author = "Stajić, Mirjana and Knezevic, A. and Vukojević, Jelena and Ćilerdžić, Jasmina and Brčeski, Ilija",
year = "2017",
abstract = "Plant raw materials could be potential sources for fibre production and this biomass could be also transformed in valued food, feed, energy sources (biofuels), and paper pulp in the processes where fungi take the major role. Effectiveness of these processes depends on capacity of the fungal species but also on the presence of trace elements which can also remarkably modulate the enzyme activity and to affect biodegradation processes. Pleurotus ostreatus HAI 493 produced ligninolytic enzymes during solid-state fermentation of grapevine sawdust with significant variability in the activity level depending on presence of Fe, Zn, or Se. Enzyme activities in trace element enriched media showed increasing of laccase activity and decreasing of Mn-oxidising peroxidase activity. The highest enlargement of laccase activity (65.9%) was noted after 10 days of cultivation in the presence of Na2SeO4. The highest inhibitory level of Mn-dependent peroxidase activity (59.6%) was noted in the presence of Na2SeO4.",
publisher = "Scibulcom Ltd, Sofia",
journal = "Journal of Environmental Protection and Ecology",
title = "Trace Elements Influence on Grapevine Degradation by Pleurotus Ostreatus",
volume = "18",
number = "4",
pages = "1498-1504",
url = "https://hdl.handle.net/21.15107/rcub_cherry_2073"
}

Stajić, M., Knezevic, A., Vukojević, J., Ćilerdžić, J.,& Brčeski, I.. (2017). Trace Elements Influence on Grapevine Degradation by Pleurotus Ostreatus. in Journal of Environmental Protection and Ecology
Scibulcom Ltd, Sofia., 18(4), 1498-1504.
https://hdl.handle.net/21.15107/rcub_cherry_2073

Stajić M, Knezevic A, Vukojević J, Ćilerdžić J, Brčeski I. Trace Elements Influence on Grapevine Degradation by Pleurotus Ostreatus. in Journal of Environmental Protection and Ecology. 2017;18(4):1498-1504.
https://hdl.handle.net/21.15107/rcub_cherry_2073 .

Stajić, Mirjana, Knezevic, A., Vukojević, Jelena, Ćilerdžić, Jasmina, Brčeski, Ilija, "Trace Elements Influence on Grapevine Degradation by Pleurotus Ostreatus" in Journal of Environmental Protection and Ecology, 18, no. 4 (2017):1498-1504,
https://hdl.handle.net/21.15107/rcub_cherry_2073 .

TY  - JOUR
AU  - Ćilerdžić, Jasmina
AU  - Galić, Milica
AU  - Vukojević, Jelena
AU  - Brčeski, Ilija
AU  - Stajić, Mirjana
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/321
AB  - Background: Structural component of plant biomass, lignocellulose, is the most abundant renewable resource in nature. Lignin is the most recalcitrant natural aromatic polymer and its degradation presents great challenge. Nowadays, the special attention is given to biological delignification, the process where white-rot fungi take the crucial place owing to strong ligninolytic enzyme system. However, fungal species, even strains, differ in potential to produce high active ligninolytic enzymes and consequently to delignify plant biomass. Therefore, the goals of the study were characterization of Mn-oxidizing peroxidases and laccases of numerous mushrooms as well as determination of their potential to delignify wheat straw, the plant raw material that, according to annual yield, takes the first place in Europe and the second one in the world. Results: During wheat straw fermentation, Lentinus edodes HAI 858 produced the most active Mn-dependent and Mn-independent peroxidases (1443.2 U L-1 and 1045.5 U L-1, respectively), while Pleurotus eryngii HAI 711 was the best laccase producer (7804.3 U L-1). Visualized bends on zymogram confirmed these activities and demonstrated that laccases were the dominant ligninolytic enzymes in the studied species. Ganoderma lucidum BEOFB 435 showed considerable ability to degrade lignin (58.5%) and especially hemicellulose (74.8%), while the cellulose remained almost intact (0.7%). Remarkable selectivity in lignocellulose degradation was also noted in Pleurotus pulmonarius HAI 573 where degraded amounts of lignin, hemicellulose and cellulose were in ratio of 50.4%:15.3%:3.8%. Conclusions: According to the presented results, it can be concluded that white-rot fungi, due to ligninolytic enzymes features and degradation potential, could be important participants in various biotechnological processes including biotransformation of lignocellulose residues/wastes in food, feed, paper and biofuels. © 2017 The Author(s).
T2  - BMC Plant Biology
T1  - Potential of selected fungal species to degrade wheat straw, the most abundant plant raw material in Europe
VL  - 17
DO  - 10.1186/s12870-017-1196-y
ER  - 

@article{
author = "Ćilerdžić, Jasmina and Galić, Milica and Vukojević, Jelena and Brčeski, Ilija and Stajić, Mirjana",
year = "2017",
abstract = "Background: Structural component of plant biomass, lignocellulose, is the most abundant renewable resource in nature. Lignin is the most recalcitrant natural aromatic polymer and its degradation presents great challenge. Nowadays, the special attention is given to biological delignification, the process where white-rot fungi take the crucial place owing to strong ligninolytic enzyme system. However, fungal species, even strains, differ in potential to produce high active ligninolytic enzymes and consequently to delignify plant biomass. Therefore, the goals of the study were characterization of Mn-oxidizing peroxidases and laccases of numerous mushrooms as well as determination of their potential to delignify wheat straw, the plant raw material that, according to annual yield, takes the first place in Europe and the second one in the world. Results: During wheat straw fermentation, Lentinus edodes HAI 858 produced the most active Mn-dependent and Mn-independent peroxidases (1443.2 U L-1 and 1045.5 U L-1, respectively), while Pleurotus eryngii HAI 711 was the best laccase producer (7804.3 U L-1). Visualized bends on zymogram confirmed these activities and demonstrated that laccases were the dominant ligninolytic enzymes in the studied species. Ganoderma lucidum BEOFB 435 showed considerable ability to degrade lignin (58.5%) and especially hemicellulose (74.8%), while the cellulose remained almost intact (0.7%). Remarkable selectivity in lignocellulose degradation was also noted in Pleurotus pulmonarius HAI 573 where degraded amounts of lignin, hemicellulose and cellulose were in ratio of 50.4%:15.3%:3.8%. Conclusions: According to the presented results, it can be concluded that white-rot fungi, due to ligninolytic enzymes features and degradation potential, could be important participants in various biotechnological processes including biotransformation of lignocellulose residues/wastes in food, feed, paper and biofuels. © 2017 The Author(s).",
journal = "BMC Plant Biology",
title = "Potential of selected fungal species to degrade wheat straw, the most abundant plant raw material in Europe",
volume = "17",
doi = "10.1186/s12870-017-1196-y"
}

Ćilerdžić, J., Galić, M., Vukojević, J., Brčeski, I.,& Stajić, M.. (2017). Potential of selected fungal species to degrade wheat straw, the most abundant plant raw material in Europe. in BMC Plant Biology, 17.
https://doi.org/10.1186/s12870-017-1196-y

Ćilerdžić J, Galić M, Vukojević J, Brčeski I, Stajić M. Potential of selected fungal species to degrade wheat straw, the most abundant plant raw material in Europe. in BMC Plant Biology. 2017;17.
doi:10.1186/s12870-017-1196-y .

Ćilerdžić, Jasmina, Galić, Milica, Vukojević, Jelena, Brčeski, Ilija, Stajić, Mirjana, "Potential of selected fungal species to degrade wheat straw, the most abundant plant raw material in Europe" in BMC Plant Biology, 17 (2017),
https://doi.org/10.1186/s12870-017-1196-y . .

TY  - JOUR
AU  - Milovanović, Ivan
AU  - Stanojković, Tatjana
AU  - Stajić, Mirjana
AU  - Brčeski, Ilija
AU  - Knežević, Aleksandar
AU  - Ćilerdžić, Jasmina
AU  - Vukojević, Jelena
PY  - 2015
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1752
AB  - The aim of the study was an assessment of the antioxidant, antifungal and cytotoxic potentials of L. betulinus and T. hirsuta mycelia extracts and the effect of selenium on these activities. Extracts of L. betulinus were twice as efficient in DPPH center dot scavenging as those of T. hirsuta. The phenol content in Se-enriched L. betulinus extracts was higher than in non-enriched extracts, in contrast to the effect of Se-enrichment on T. hirsuta extracts, and a direct correlation between the amount and DPPH center dot scavenging effect was observed. Ethanol extracts exhibited fungistatic but not fungicidal activity against a range of micromycetes, and mycelium enrichment with selenium inhibited this effect. Although the extracts showed low cytotoxic activity against HeLa and LS174 cells, T. hirsuta extracts, especially those enriched with selenium, had better potential. L. betulinus extracts showed better antioxidant and antifungal activity than T. hirsuta extracts which were more active cytotoxic agents. The presence of selenium stimulated antioxidant and cytotoxic, and inhibited antifungal activity in L. betulinus, while in T. hirsuta its effect was slight.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Current Pharmaceutical Biotechnology
T1  - Effect of Selenium Enrichment of Lenzites betulinus and Trametes hirsuta Mycelia on Antioxidant, Antifungal and Cytostatics Potential
VL  - 16
IS  - 10
SP  - 920
EP  - 926
DO  - 10.2174/1389201016666150618152531
ER  - 

@article{
author = "Milovanović, Ivan and Stanojković, Tatjana and Stajić, Mirjana and Brčeski, Ilija and Knežević, Aleksandar and Ćilerdžić, Jasmina and Vukojević, Jelena",
year = "2015",
abstract = "The aim of the study was an assessment of the antioxidant, antifungal and cytotoxic potentials of L. betulinus and T. hirsuta mycelia extracts and the effect of selenium on these activities. Extracts of L. betulinus were twice as efficient in DPPH center dot scavenging as those of T. hirsuta. The phenol content in Se-enriched L. betulinus extracts was higher than in non-enriched extracts, in contrast to the effect of Se-enrichment on T. hirsuta extracts, and a direct correlation between the amount and DPPH center dot scavenging effect was observed. Ethanol extracts exhibited fungistatic but not fungicidal activity against a range of micromycetes, and mycelium enrichment with selenium inhibited this effect. Although the extracts showed low cytotoxic activity against HeLa and LS174 cells, T. hirsuta extracts, especially those enriched with selenium, had better potential. L. betulinus extracts showed better antioxidant and antifungal activity than T. hirsuta extracts which were more active cytotoxic agents. The presence of selenium stimulated antioxidant and cytotoxic, and inhibited antifungal activity in L. betulinus, while in T. hirsuta its effect was slight.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Current Pharmaceutical Biotechnology",
title = "Effect of Selenium Enrichment of Lenzites betulinus and Trametes hirsuta Mycelia on Antioxidant, Antifungal and Cytostatics Potential",
volume = "16",
number = "10",
pages = "920-926",
doi = "10.2174/1389201016666150618152531"
}

Milovanović, I., Stanojković, T., Stajić, M., Brčeski, I., Knežević, A., Ćilerdžić, J.,& Vukojević, J.. (2015). Effect of Selenium Enrichment of Lenzites betulinus and Trametes hirsuta Mycelia on Antioxidant, Antifungal and Cytostatics Potential. in Current Pharmaceutical Biotechnology
Bentham Science Publ Ltd, Sharjah., 16(10), 920-926.
https://doi.org/10.2174/1389201016666150618152531

Milovanović I, Stanojković T, Stajić M, Brčeski I, Knežević A, Ćilerdžić J, Vukojević J. Effect of Selenium Enrichment of Lenzites betulinus and Trametes hirsuta Mycelia on Antioxidant, Antifungal and Cytostatics Potential. in Current Pharmaceutical Biotechnology. 2015;16(10):920-926.
doi:10.2174/1389201016666150618152531 .

Milovanović, Ivan, Stanojković, Tatjana, Stajić, Mirjana, Brčeski, Ilija, Knežević, Aleksandar, Ćilerdžić, Jasmina, Vukojević, Jelena, "Effect of Selenium Enrichment of Lenzites betulinus and Trametes hirsuta Mycelia on Antioxidant, Antifungal and Cytostatics Potential" in Current Pharmaceutical Biotechnology, 16, no. 10 (2015):920-926,
https://doi.org/10.2174/1389201016666150618152531 . .

TY  - JOUR
AU  - Ćilerdžić, Jasmina
AU  - Stajić, Mirjana
AU  - Vukojević, Jelena
AU  - Lončar, Nikola L.
PY  - 2014
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1872
AB  - Ganoderma lucidum has a well-developed ligninolytic enzyme system, where laccase is the dominant and sometimes only synthesizing enzyme, and therefore could find an application in the delignification of abundant plant raw materials and in food, feed, paper, and biofuel production. The questions that provided the goals for the present study were whether the profile of G. lucidum laccase depends on cultivation type and carbon source, as well as whether intraspecific diversity exists. Conditions of submerged cultivation proved more preferable for laccase activity compared with solid-state cultivations in all studied strains, while oak sawdust provided a better carbon source than wheat straw. Maximum laccase activity (7241.0 U/L) was measured on day 14 of oak sawdust submerged fermentation by strain BEOFB 431. Intraspecific diversity in synthesized proteins was more significant in wheat straw than in oak sawdust submerged fermentation. The profile of laccase isoforms was dependent on strain, plant residue, type, and period of cultivation. Four acidic laccase isoforms (pl 3.6) were detected in G. lucidum BEOFB 431 at the same cultivation point where maximal enzyme activity was measured.
PB  - North Carolina State Univ Dept Wood & Paper Sci, Raleigh
T2  - BioResources
T1  - Intraspecific Diversity in the Production and Characterization of Laccase within Ganoderma lucidum
VL  - 9
IS  - 3
SP  - 5577
EP  - 5587
UR  - https://hdl.handle.net/21.15107/rcub_cherry_1872
ER  - 

@article{
author = "Ćilerdžić, Jasmina and Stajić, Mirjana and Vukojević, Jelena and Lončar, Nikola L.",
year = "2014",
abstract = "Ganoderma lucidum has a well-developed ligninolytic enzyme system, where laccase is the dominant and sometimes only synthesizing enzyme, and therefore could find an application in the delignification of abundant plant raw materials and in food, feed, paper, and biofuel production. The questions that provided the goals for the present study were whether the profile of G. lucidum laccase depends on cultivation type and carbon source, as well as whether intraspecific diversity exists. Conditions of submerged cultivation proved more preferable for laccase activity compared with solid-state cultivations in all studied strains, while oak sawdust provided a better carbon source than wheat straw. Maximum laccase activity (7241.0 U/L) was measured on day 14 of oak sawdust submerged fermentation by strain BEOFB 431. Intraspecific diversity in synthesized proteins was more significant in wheat straw than in oak sawdust submerged fermentation. The profile of laccase isoforms was dependent on strain, plant residue, type, and period of cultivation. Four acidic laccase isoforms (pl 3.6) were detected in G. lucidum BEOFB 431 at the same cultivation point where maximal enzyme activity was measured.",
publisher = "North Carolina State Univ Dept Wood & Paper Sci, Raleigh",
journal = "BioResources",
title = "Intraspecific Diversity in the Production and Characterization of Laccase within Ganoderma lucidum",
volume = "9",
number = "3",
pages = "5577-5587",
url = "https://hdl.handle.net/21.15107/rcub_cherry_1872"
}

Ćilerdžić, J., Stajić, M., Vukojević, J.,& Lončar, N. L.. (2014). Intraspecific Diversity in the Production and Characterization of Laccase within Ganoderma lucidum. in BioResources
North Carolina State Univ Dept Wood & Paper Sci, Raleigh., 9(3), 5577-5587.
https://hdl.handle.net/21.15107/rcub_cherry_1872

Ćilerdžić J, Stajić M, Vukojević J, Lončar NL. Intraspecific Diversity in the Production and Characterization of Laccase within Ganoderma lucidum. in BioResources. 2014;9(3):5577-5587.
https://hdl.handle.net/21.15107/rcub_cherry_1872 .

Ćilerdžić, Jasmina, Stajić, Mirjana, Vukojević, Jelena, Lončar, Nikola L., "Intraspecific Diversity in the Production and Characterization of Laccase within Ganoderma lucidum" in BioResources, 9, no. 3 (2014):5577-5587,
https://hdl.handle.net/21.15107/rcub_cherry_1872 .

TY  - JOUR
AU  - Knežević, Aleksandar
AU  - Milovanović, Ivan
AU  - Stajić, Mirjana
AU  - Lončar, Nikola L.
AU  - Brčeski, Ilija
AU  - Vukojević, Jelena
AU  - Ćilerdžić, Jasmina
PY  - 2013
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1364
AB  - As biological decomposition of plant biomass represents a popular alternative environmental-friendly and economically justified process, screening of ligninolytic enzyme systems of various fungal species is a topical study area. The goal of the study was to obtain clear insight into the dynamics of laccase, Mn-dependent peroxidase, and Mn-independent peroxidase activity and levels of wheat straw lignin degradation in seven wood-rotting fungi. The best laccase producers were Pleurotus ostreatus and Pleurotus eryngii. Lenzites betulinus and Fomitopsis pinicola were the best Mn-dependent peroxidase producers, and P. ostreatus the weakest one. The peak of Mn-independent peroxidase was noted in Dichomytus squalens, and the minimum value in P. ostreatus. The profiles of the three enzymes, obtained by isoelectric focusing, were variable depending on the species and cultivation period. D. squalens was the best lignin degrader (34.1% of total lignin amount), and P. ostreatus and P. eryngii the weakest ones (7.1% and 14.5%, respectively).
PB  - Elsevier Sci Ltd, Oxford
T2  - Bioresource Technology
T1  - Lignin degradation by selected fungal species
VL  - 138
SP  - 117
EP  - 123
DO  - 10.1016/j.biortech.2013.03.182
ER  - 

@article{
author = "Knežević, Aleksandar and Milovanović, Ivan and Stajić, Mirjana and Lončar, Nikola L. and Brčeski, Ilija and Vukojević, Jelena and Ćilerdžić, Jasmina",
year = "2013",
abstract = "As biological decomposition of plant biomass represents a popular alternative environmental-friendly and economically justified process, screening of ligninolytic enzyme systems of various fungal species is a topical study area. The goal of the study was to obtain clear insight into the dynamics of laccase, Mn-dependent peroxidase, and Mn-independent peroxidase activity and levels of wheat straw lignin degradation in seven wood-rotting fungi. The best laccase producers were Pleurotus ostreatus and Pleurotus eryngii. Lenzites betulinus and Fomitopsis pinicola were the best Mn-dependent peroxidase producers, and P. ostreatus the weakest one. The peak of Mn-independent peroxidase was noted in Dichomytus squalens, and the minimum value in P. ostreatus. The profiles of the three enzymes, obtained by isoelectric focusing, were variable depending on the species and cultivation period. D. squalens was the best lignin degrader (34.1% of total lignin amount), and P. ostreatus and P. eryngii the weakest ones (7.1% and 14.5%, respectively).",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Bioresource Technology",
title = "Lignin degradation by selected fungal species",
volume = "138",
pages = "117-123",
doi = "10.1016/j.biortech.2013.03.182"
}

Knežević, A., Milovanović, I., Stajić, M., Lončar, N. L., Brčeski, I., Vukojević, J.,& Ćilerdžić, J.. (2013). Lignin degradation by selected fungal species. in Bioresource Technology
Elsevier Sci Ltd, Oxford., 138, 117-123.
https://doi.org/10.1016/j.biortech.2013.03.182

Knežević A, Milovanović I, Stajić M, Lončar NL, Brčeski I, Vukojević J, Ćilerdžić J. Lignin degradation by selected fungal species. in Bioresource Technology. 2013;138:117-123.
doi:10.1016/j.biortech.2013.03.182 .

Knežević, Aleksandar, Milovanović, Ivan, Stajić, Mirjana, Lončar, Nikola L., Brčeski, Ilija, Vukojević, Jelena, Ćilerdžić, Jasmina, "Lignin degradation by selected fungal species" in Bioresource Technology, 138 (2013):117-123,
https://doi.org/10.1016/j.biortech.2013.03.182 . .