TY  - JOUR
AU  - Covaliu, Cristina Ileana
AU  - Paraschiv, Gigel
AU  - Biris, Sorin-Stefan
AU  - Jitaru, Ioana
AU  - Vasile, Eugeniu
AU  - Diamandescu, Lucian
AU  - Ćirković-Veličković, Tanja
AU  - Krstić-Ristivojević, Maja
AU  - Ionita, Valentin
AU  - Iovu, Horia
AU  - Matei, Ecaterina
PY  - 2013
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1421
AB  - This paper deals with the synthesis of two nanohybrid materials based on maghemite (gamma-Fe2O3) and poly-DL-alanine using a two-step procedure consisting of maghemite nanoparticles synthesis by microemulsion method and nanohybrids obtaining by coating of maghemite nanoparticles with poly-DL-alanine biopolymer in two different molar ratios (H1:5 and H1: 15). The maghemite and their corresponding nanohybrids were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, X-ray photoemission spectroscopy, Mossbauer spectroscopy, Transmission electron microscopy, High resolution transmission electron microscopy with selected area electron diffraction and Atomic absorption spectroscopy. The two nanohybrids under the investigation have the average particle sizes of 22 nm and 23 nm. The Fourier transform infrared spectroscopy spectra and X-ray photoemission spectroscopy data indicate the existence of some interactions between the maghemite nanoparticles and poly-DL-alanine shell. The saturation magnetization values for maghemite and the two nanohybrids determined by a Vibrating Sample Magnetometer correspond to a typical superparamagnetic behavior suitable for applying in biomedical field. Also, with respect of biomedical application the biological activity of maghemite and its corresponding nanohybrids was investigated on healthy human cells (PBMC) and cancerous cells (HeLa). Furthermore, in order to support the multifunctionality of the gamma-Fe2O3 sample and nanohybrids we also investigated their wastewater treatment properties by measuring the removal efficiency of heavy metal Cd (II) ions.
PB  - Elsevier Science Bv, Amsterdam
T2  - Applied Surface Science
T1  - Maghemite and poly-DL-alanine based core-shell multifunctional nanohybrids for environmental protection and biomedicine applications
VL  - 285
SP  - 86
EP  - 95
DO  - 10.1016/j.apsusc.2013.08.059
ER  - 

@article{
author = "Covaliu, Cristina Ileana and Paraschiv, Gigel and Biris, Sorin-Stefan and Jitaru, Ioana and Vasile, Eugeniu and Diamandescu, Lucian and Ćirković-Veličković, Tanja and Krstić-Ristivojević, Maja and Ionita, Valentin and Iovu, Horia and Matei, Ecaterina",
year = "2013",
abstract = "This paper deals with the synthesis of two nanohybrid materials based on maghemite (gamma-Fe2O3) and poly-DL-alanine using a two-step procedure consisting of maghemite nanoparticles synthesis by microemulsion method and nanohybrids obtaining by coating of maghemite nanoparticles with poly-DL-alanine biopolymer in two different molar ratios (H1:5 and H1: 15). The maghemite and their corresponding nanohybrids were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, X-ray photoemission spectroscopy, Mossbauer spectroscopy, Transmission electron microscopy, High resolution transmission electron microscopy with selected area electron diffraction and Atomic absorption spectroscopy. The two nanohybrids under the investigation have the average particle sizes of 22 nm and 23 nm. The Fourier transform infrared spectroscopy spectra and X-ray photoemission spectroscopy data indicate the existence of some interactions between the maghemite nanoparticles and poly-DL-alanine shell. The saturation magnetization values for maghemite and the two nanohybrids determined by a Vibrating Sample Magnetometer correspond to a typical superparamagnetic behavior suitable for applying in biomedical field. Also, with respect of biomedical application the biological activity of maghemite and its corresponding nanohybrids was investigated on healthy human cells (PBMC) and cancerous cells (HeLa). Furthermore, in order to support the multifunctionality of the gamma-Fe2O3 sample and nanohybrids we also investigated their wastewater treatment properties by measuring the removal efficiency of heavy metal Cd (II) ions.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Applied Surface Science",
title = "Maghemite and poly-DL-alanine based core-shell multifunctional nanohybrids for environmental protection and biomedicine applications",
volume = "285",
pages = "86-95",
doi = "10.1016/j.apsusc.2013.08.059"
}

Covaliu, C. I., Paraschiv, G., Biris, S., Jitaru, I., Vasile, E., Diamandescu, L., Ćirković-Veličković, T., Krstić-Ristivojević, M., Ionita, V., Iovu, H.,& Matei, E.. (2013). Maghemite and poly-DL-alanine based core-shell multifunctional nanohybrids for environmental protection and biomedicine applications. in Applied Surface Science
Elsevier Science Bv, Amsterdam., 285, 86-95.
https://doi.org/10.1016/j.apsusc.2013.08.059

Covaliu CI, Paraschiv G, Biris S, Jitaru I, Vasile E, Diamandescu L, Ćirković-Veličković T, Krstić-Ristivojević M, Ionita V, Iovu H, Matei E. Maghemite and poly-DL-alanine based core-shell multifunctional nanohybrids for environmental protection and biomedicine applications. in Applied Surface Science. 2013;285:86-95.
doi:10.1016/j.apsusc.2013.08.059 .

Covaliu, Cristina Ileana, Paraschiv, Gigel, Biris, Sorin-Stefan, Jitaru, Ioana, Vasile, Eugeniu, Diamandescu, Lucian, Ćirković-Veličković, Tanja, Krstić-Ristivojević, Maja, Ionita, Valentin, Iovu, Horia, Matei, Ecaterina, "Maghemite and poly-DL-alanine based core-shell multifunctional nanohybrids for environmental protection and biomedicine applications" in Applied Surface Science, 285 (2013):86-95,
https://doi.org/10.1016/j.apsusc.2013.08.059 . .

TY  - JOUR
AU  - Alexandru, Maria-Gabriela
AU  - Ćirković-Veličković, Tanja
AU  - Jitaru, Ioana
AU  - Grgurić-Šipka, Sanja
AU  - Draghici, Constantin
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1075
AB  - This paper presents the synthesis of complex compounds of type [M(L1)(2)], where M(II) = Cu (1), Co (2), Zn (3), L1 = 2-aminothiazole-4-acetate and [Mn(L1)(2)(H2O)] (4) using ethyl 2-(2-aminothiazole-4-yl) acetate (L), and characterization by elemental analysis, magnetic susceptibilities, IR, 1H-NMR, UV-Vis spectroscopy and for [Mn(L1)(2)(H2O)] also by X-ray diffraction. In vitro cytotoxicity studies were performed on human cervix adenocarcinoma, HeLa cells. The antitumor selectivity was assessed using normal human peripheral blood mononuclear cells, PBMC as control.
PB  - De Gruyter Poland Sp Zoo, Warsaw
T2  - Central European Journal of Chemistry
T1  - Synthesis, characterization and antitumor activity of Cu(II), Co(II), Zn(II) and Mn(II) complex compounds with aminothiazole acetate derivative
VL  - 8
IS  - 3
SP  - 639
EP  - 645
DO  - 10.2478/s11532-010-0022-2
ER  - 

@article{
author = "Alexandru, Maria-Gabriela and Ćirković-Veličković, Tanja and Jitaru, Ioana and Grgurić-Šipka, Sanja and Draghici, Constantin",
year = "2010",
abstract = "This paper presents the synthesis of complex compounds of type [M(L1)(2)], where M(II) = Cu (1), Co (2), Zn (3), L1 = 2-aminothiazole-4-acetate and [Mn(L1)(2)(H2O)] (4) using ethyl 2-(2-aminothiazole-4-yl) acetate (L), and characterization by elemental analysis, magnetic susceptibilities, IR, 1H-NMR, UV-Vis spectroscopy and for [Mn(L1)(2)(H2O)] also by X-ray diffraction. In vitro cytotoxicity studies were performed on human cervix adenocarcinoma, HeLa cells. The antitumor selectivity was assessed using normal human peripheral blood mononuclear cells, PBMC as control.",
publisher = "De Gruyter Poland Sp Zoo, Warsaw",
journal = "Central European Journal of Chemistry",
title = "Synthesis, characterization and antitumor activity of Cu(II), Co(II), Zn(II) and Mn(II) complex compounds with aminothiazole acetate derivative",
volume = "8",
number = "3",
pages = "639-645",
doi = "10.2478/s11532-010-0022-2"
}

Alexandru, M., Ćirković-Veličković, T., Jitaru, I., Grgurić-Šipka, S.,& Draghici, C.. (2010). Synthesis, characterization and antitumor activity of Cu(II), Co(II), Zn(II) and Mn(II) complex compounds with aminothiazole acetate derivative. in Central European Journal of Chemistry
De Gruyter Poland Sp Zoo, Warsaw., 8(3), 639-645.
https://doi.org/10.2478/s11532-010-0022-2

Alexandru M, Ćirković-Veličković T, Jitaru I, Grgurić-Šipka S, Draghici C. Synthesis, characterization and antitumor activity of Cu(II), Co(II), Zn(II) and Mn(II) complex compounds with aminothiazole acetate derivative. in Central European Journal of Chemistry. 2010;8(3):639-645.
doi:10.2478/s11532-010-0022-2 .

Alexandru, Maria-Gabriela, Ćirković-Veličković, Tanja, Jitaru, Ioana, Grgurić-Šipka, Sanja, Draghici, Constantin, "Synthesis, characterization and antitumor activity of Cu(II), Co(II), Zn(II) and Mn(II) complex compounds with aminothiazole acetate derivative" in Central European Journal of Chemistry, 8, no. 3 (2010):639-645,
https://doi.org/10.2478/s11532-010-0022-2 . .