TY  - JOUR
AU  - Cinková, Kristína
AU  - Kianicková, Kristína
AU  - Stanković, Dalibor
AU  - Vojs, Marian
AU  - Marton, Marian
AU  - Šovrc, Ľubomír
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2102
AB  - In this work, the electrochemical oxidation and subsequent determination of uric acid was investigated using boron-doped diamond electrodes with various B/C ratios (0-2000 ppm). The cyclic voltammetric study showed one irreversible oxidation peak at +(1.1-1.25) V (vs. Ag/AgCl/3 M KCl) in the presence of Britton-Robinson buffer (pH 2.25) depending on the boron content. Employing differential pulse voltammetry using the 2000 ppm boron-doped diamond electrode the acquired analytical parameters were as follows: a limit of detection of 7.7 M, a limit of quantification of 26 M and intra-day repeatability (relative standard deviation of 2.9% for n = 15). After performing an interference study, the method was applied to the determination of uric acid in biological samples (human urine). The uric acid concentrations determined in the urine samples were compared with the reference values stated in the literature. The proposed methodology using boron-doped diamond electrodes could find applications in uric acid sensing within clinical, pharmaceutical and environmental analysis.
PB  - Royal Soc Chemistry, Cambridge
T2  - Analytical Methods
T1  - The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid
VL  - 10
IS  - 9
SP  - 991
EP  - 996
DO  - 10.1039/c7ay02720f
ER  - 

@article{
author = "Cinková, Kristína and Kianicková, Kristína and Stanković, Dalibor and Vojs, Marian and Marton, Marian and Šovrc, Ľubomír",
year = "2018",
abstract = "In this work, the electrochemical oxidation and subsequent determination of uric acid was investigated using boron-doped diamond electrodes with various B/C ratios (0-2000 ppm). The cyclic voltammetric study showed one irreversible oxidation peak at +(1.1-1.25) V (vs. Ag/AgCl/3 M KCl) in the presence of Britton-Robinson buffer (pH 2.25) depending on the boron content. Employing differential pulse voltammetry using the 2000 ppm boron-doped diamond electrode the acquired analytical parameters were as follows: a limit of detection of 7.7 M, a limit of quantification of 26 M and intra-day repeatability (relative standard deviation of 2.9% for n = 15). After performing an interference study, the method was applied to the determination of uric acid in biological samples (human urine). The uric acid concentrations determined in the urine samples were compared with the reference values stated in the literature. The proposed methodology using boron-doped diamond electrodes could find applications in uric acid sensing within clinical, pharmaceutical and environmental analysis.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Analytical Methods",
title = "The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid",
volume = "10",
number = "9",
pages = "991-996",
doi = "10.1039/c7ay02720f"
}

Cinková, K., Kianicková, K., Stanković, D., Vojs, M., Marton, M.,& Šovrc, Ľ.. (2018). The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid. in Analytical Methods
Royal Soc Chemistry, Cambridge., 10(9), 991-996.
https://doi.org/10.1039/c7ay02720f

Cinková K, Kianicková K, Stanković D, Vojs M, Marton M, Šovrc Ľ. The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid. in Analytical Methods. 2018;10(9):991-996.
doi:10.1039/c7ay02720f .

Cinková, Kristína, Kianicková, Kristína, Stanković, Dalibor, Vojs, Marian, Marton, Marian, Šovrc, Ľubomír, "The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid" in Analytical Methods, 10, no. 9 (2018):991-996,
https://doi.org/10.1039/c7ay02720f . .

TY  - DATA
AU  - Šovrc, Ľubomír
AU  - Borovska, Katarina
AU  - Cinková, Kristína
AU  - Stanković, Dalibor
AU  - Planková, Alexandra
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2997
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Electrochimica Acta
T1  - Supplementary data for article: Šovrc, Ľ.; Borovska, K.; Cinková, K.; Stanković, D.; Planková, A. Advanced Electrochemical Platform for Determination of Cytostatic Drug Flutamide in Various Matrices Using a Boron-Doped Diamond Electrode. Electrochimica Acta 2017, 251, 621–630. https://doi.org/10.1016/j.electacta.2017.08.077
UR  - https://hdl.handle.net/21.15107/rcub_cherry_2997
ER  - 

@misc{
author = "Šovrc, Ľubomír and Borovska, Katarina and Cinková, Kristína and Stanković, Dalibor and Planková, Alexandra",
year = "2017",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Electrochimica Acta",
title = "Supplementary data for article: Šovrc, Ľ.; Borovska, K.; Cinková, K.; Stanković, D.; Planková, A. Advanced Electrochemical Platform for Determination of Cytostatic Drug Flutamide in Various Matrices Using a Boron-Doped Diamond Electrode. Electrochimica Acta 2017, 251, 621–630. https://doi.org/10.1016/j.electacta.2017.08.077",
url = "https://hdl.handle.net/21.15107/rcub_cherry_2997"
}

Šovrc, Ľ., Borovska, K., Cinková, K., Stanković, D.,& Planková, A.. (2017). Supplementary data for article: Šovrc, Ľ.; Borovska, K.; Cinková, K.; Stanković, D.; Planková, A. Advanced Electrochemical Platform for Determination of Cytostatic Drug Flutamide in Various Matrices Using a Boron-Doped Diamond Electrode. Electrochimica Acta 2017, 251, 621–630. https://doi.org/10.1016/j.electacta.2017.08.077. in Electrochimica Acta
Pergamon-Elsevier Science Ltd, Oxford..
https://hdl.handle.net/21.15107/rcub_cherry_2997

Šovrc Ľ, Borovska K, Cinková K, Stanković D, Planková A. Supplementary data for article: Šovrc, Ľ.; Borovska, K.; Cinková, K.; Stanković, D.; Planková, A. Advanced Electrochemical Platform for Determination of Cytostatic Drug Flutamide in Various Matrices Using a Boron-Doped Diamond Electrode. Electrochimica Acta 2017, 251, 621–630. https://doi.org/10.1016/j.electacta.2017.08.077. in Electrochimica Acta. 2017;.
https://hdl.handle.net/21.15107/rcub_cherry_2997 .

Šovrc, Ľubomír, Borovska, Katarina, Cinková, Kristína, Stanković, Dalibor, Planková, Alexandra, "Supplementary data for article: Šovrc, Ľ.; Borovska, K.; Cinková, K.; Stanković, D.; Planková, A. Advanced Electrochemical Platform for Determination of Cytostatic Drug Flutamide in Various Matrices Using a Boron-Doped Diamond Electrode. Electrochimica Acta 2017, 251, 621–630. https://doi.org/10.1016/j.electacta.2017.08.077" in Electrochimica Acta (2017),
https://hdl.handle.net/21.15107/rcub_cherry_2997 .

TY  - JOUR
AU  - Šovrc, Ľubomír
AU  - Borovska, Katarina
AU  - Cinková, Kristína
AU  - Stanković, Dalibor
AU  - Planková, Alexandra
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2996
AB  - An innovative, rapid and simple electrochemical approach for the reliable quantification of cytostatic drug flutamide (FLU) in various matrices is herein proposed. This platform involves coupling of differential pulse (DPV) and square-wave voltammetry (SWV) with a boron-doped diamond (BDD) electrode as the working electrode and 0.1 M sulphuric acid as the supporting electrolyte. For the first time, the voltammetric profile of FLU was manifested by three irreversible and diffusion-controlled oxidation peaks at + 1.1 (P1), + 1.4 (P2) and + 1.9 V (P3). The analytical performance evaluation was assessed for all three peaks, using both pulse voltammetric techniques with the optimized operating parameters and the highest sensitivity of 1.76 nA/mu M was accomplished for P2 using DPV and 3.54 nA/mu M for P3 using SWV. The corresponding linear concentration ranges were found to be 0.99-42.9 and 4.8-35.5 mu M with the detection limits of 0.42 and 0.18 mu M, respectively. The repeatability varied, depending on the oxidation peaks of FLU, with the relative standard deviations in the range of 3.3-8.8% and 2.9-9.3% for DPV and SWV, respectively. The proposed electrochemical platform was successfully applied in the analysis of pharmaceutical formulations, spiked human urine and water samples with the significant mean recoveries. Using BDD electrode, the current work establishes an advanced, simple and rapid alternative platform to so far used toxic mercury-based electrodes and time demanding chemically modified electrodes in cytostatic sensing. Besides, BDD electrode represents a comfortable electrochemical sensor for routine analysis in pharmaceutical, clinical and environmental chemistry.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Electrochimica Acta
T1  - Advanced electrochemical platform for determination of cytostatic drug flutamide in various matrices using a boron-doped diamond electrode
VL  - 251
SP  - 621
EP  - 630
DO  - 10.1016/j.electacta.2017.08.077
ER  - 

@article{
author = "Šovrc, Ľubomír and Borovska, Katarina and Cinková, Kristína and Stanković, Dalibor and Planková, Alexandra",
year = "2017",
abstract = "An innovative, rapid and simple electrochemical approach for the reliable quantification of cytostatic drug flutamide (FLU) in various matrices is herein proposed. This platform involves coupling of differential pulse (DPV) and square-wave voltammetry (SWV) with a boron-doped diamond (BDD) electrode as the working electrode and 0.1 M sulphuric acid as the supporting electrolyte. For the first time, the voltammetric profile of FLU was manifested by three irreversible and diffusion-controlled oxidation peaks at + 1.1 (P1), + 1.4 (P2) and + 1.9 V (P3). The analytical performance evaluation was assessed for all three peaks, using both pulse voltammetric techniques with the optimized operating parameters and the highest sensitivity of 1.76 nA/mu M was accomplished for P2 using DPV and 3.54 nA/mu M for P3 using SWV. The corresponding linear concentration ranges were found to be 0.99-42.9 and 4.8-35.5 mu M with the detection limits of 0.42 and 0.18 mu M, respectively. The repeatability varied, depending on the oxidation peaks of FLU, with the relative standard deviations in the range of 3.3-8.8% and 2.9-9.3% for DPV and SWV, respectively. The proposed electrochemical platform was successfully applied in the analysis of pharmaceutical formulations, spiked human urine and water samples with the significant mean recoveries. Using BDD electrode, the current work establishes an advanced, simple and rapid alternative platform to so far used toxic mercury-based electrodes and time demanding chemically modified electrodes in cytostatic sensing. Besides, BDD electrode represents a comfortable electrochemical sensor for routine analysis in pharmaceutical, clinical and environmental chemistry.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Electrochimica Acta",
title = "Advanced electrochemical platform for determination of cytostatic drug flutamide in various matrices using a boron-doped diamond electrode",
volume = "251",
pages = "621-630",
doi = "10.1016/j.electacta.2017.08.077"
}

Šovrc, Ľ., Borovska, K., Cinková, K., Stanković, D.,& Planková, A.. (2017). Advanced electrochemical platform for determination of cytostatic drug flutamide in various matrices using a boron-doped diamond electrode. in Electrochimica Acta
Pergamon-Elsevier Science Ltd, Oxford., 251, 621-630.
https://doi.org/10.1016/j.electacta.2017.08.077

Šovrc Ľ, Borovska K, Cinková K, Stanković D, Planková A. Advanced electrochemical platform for determination of cytostatic drug flutamide in various matrices using a boron-doped diamond electrode. in Electrochimica Acta. 2017;251:621-630.
doi:10.1016/j.electacta.2017.08.077 .

Šovrc, Ľubomír, Borovska, Katarina, Cinková, Kristína, Stanković, Dalibor, Planková, Alexandra, "Advanced electrochemical platform for determination of cytostatic drug flutamide in various matrices using a boron-doped diamond electrode" in Electrochimica Acta, 251 (2017):621-630,
https://doi.org/10.1016/j.electacta.2017.08.077 . .

TY  - JOUR
AU  - Šovrc, Ľubomír
AU  - Borovska, Katarina
AU  - Cinková, Kristína
AU  - Stanković, Dalibor
AU  - Planková, Alexandra
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2540
AB  - An innovative, rapid and simple electrochemical approach for the reliable quantification of cytostatic drug flutamide (FLU) in various matrices is herein proposed. This platform involves coupling of differential pulse (DPV) and square-wave voltammetry (SWV) with a boron-doped diamond (BDD) electrode as the working electrode and 0.1 M sulphuric acid as the supporting electrolyte. For the first time, the voltammetric profile of FLU was manifested by three irreversible and diffusion-controlled oxidation peaks at + 1.1 (P1), + 1.4 (P2) and + 1.9 V (P3). The analytical performance evaluation was assessed for all three peaks, using both pulse voltammetric techniques with the optimized operating parameters and the highest sensitivity of 1.76 nA/mu M was accomplished for P2 using DPV and 3.54 nA/mu M for P3 using SWV. The corresponding linear concentration ranges were found to be 0.99-42.9 and 4.8-35.5 mu M with the detection limits of 0.42 and 0.18 mu M, respectively. The repeatability varied, depending on the oxidation peaks of FLU, with the relative standard deviations in the range of 3.3-8.8% and 2.9-9.3% for DPV and SWV, respectively. The proposed electrochemical platform was successfully applied in the analysis of pharmaceutical formulations, spiked human urine and water samples with the significant mean recoveries. Using BDD electrode, the current work establishes an advanced, simple and rapid alternative platform to so far used toxic mercury-based electrodes and time demanding chemically modified electrodes in cytostatic sensing. Besides, BDD electrode represents a comfortable electrochemical sensor for routine analysis in pharmaceutical, clinical and environmental chemistry. (C) 2017 Elsevier Ltd. All rights reserved.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Electrochimica Acta
T1  - Advanced electrochemical platform for determination of cytostatic drug flutamide in various matrices using a boron-doped diamond electrode
VL  - 251
SP  - 621
EP  - 630
DO  - 10.1016/j.electacta.2017.08.077
ER  - 

@article{
author = "Šovrc, Ľubomír and Borovska, Katarina and Cinková, Kristína and Stanković, Dalibor and Planková, Alexandra",
year = "2017",
abstract = "An innovative, rapid and simple electrochemical approach for the reliable quantification of cytostatic drug flutamide (FLU) in various matrices is herein proposed. This platform involves coupling of differential pulse (DPV) and square-wave voltammetry (SWV) with a boron-doped diamond (BDD) electrode as the working electrode and 0.1 M sulphuric acid as the supporting electrolyte. For the first time, the voltammetric profile of FLU was manifested by three irreversible and diffusion-controlled oxidation peaks at + 1.1 (P1), + 1.4 (P2) and + 1.9 V (P3). The analytical performance evaluation was assessed for all three peaks, using both pulse voltammetric techniques with the optimized operating parameters and the highest sensitivity of 1.76 nA/mu M was accomplished for P2 using DPV and 3.54 nA/mu M for P3 using SWV. The corresponding linear concentration ranges were found to be 0.99-42.9 and 4.8-35.5 mu M with the detection limits of 0.42 and 0.18 mu M, respectively. The repeatability varied, depending on the oxidation peaks of FLU, with the relative standard deviations in the range of 3.3-8.8% and 2.9-9.3% for DPV and SWV, respectively. The proposed electrochemical platform was successfully applied in the analysis of pharmaceutical formulations, spiked human urine and water samples with the significant mean recoveries. Using BDD electrode, the current work establishes an advanced, simple and rapid alternative platform to so far used toxic mercury-based electrodes and time demanding chemically modified electrodes in cytostatic sensing. Besides, BDD electrode represents a comfortable electrochemical sensor for routine analysis in pharmaceutical, clinical and environmental chemistry. (C) 2017 Elsevier Ltd. All rights reserved.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Electrochimica Acta",
title = "Advanced electrochemical platform for determination of cytostatic drug flutamide in various matrices using a boron-doped diamond electrode",
volume = "251",
pages = "621-630",
doi = "10.1016/j.electacta.2017.08.077"
}

Šovrc, Ľ., Borovska, K., Cinková, K., Stanković, D.,& Planková, A.. (2017). Advanced electrochemical platform for determination of cytostatic drug flutamide in various matrices using a boron-doped diamond electrode. in Electrochimica Acta
Pergamon-Elsevier Science Ltd, Oxford., 251, 621-630.
https://doi.org/10.1016/j.electacta.2017.08.077

Šovrc Ľ, Borovska K, Cinková K, Stanković D, Planková A. Advanced electrochemical platform for determination of cytostatic drug flutamide in various matrices using a boron-doped diamond electrode. in Electrochimica Acta. 2017;251:621-630.
doi:10.1016/j.electacta.2017.08.077 .

Šovrc, Ľubomír, Borovska, Katarina, Cinková, Kristína, Stanković, Dalibor, Planková, Alexandra, "Advanced electrochemical platform for determination of cytostatic drug flutamide in various matrices using a boron-doped diamond electrode" in Electrochimica Acta, 251 (2017):621-630,
https://doi.org/10.1016/j.electacta.2017.08.077 . .

TY  - JOUR
AU  - Šovrc, Ľubomír
AU  - Cinková, Kristína
AU  - Samphao, Anchalee
AU  - Stanković, Dalibor
AU  - Mehmeti, Eda
AU  - Kalcher, Kurt
PY  - 2015
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1702
AB  - A novel analytical approach for the sensitive determination of a beta-carboline alkaloid, harmaline, was developed using pulse voltammetric techniques with a boron-doped diamond electrode. Cyclic voltammetry showed two irreversible oxidation peaks at about +0.90 and +1.20 V (vs. Ag/AgCl) in Britton-Robinson buffer solution at pH 5. Under optimized experimental conditions, differential pulse and square-wave voltammetry were elaborated for the determination of harmaline in a linear concentration range from 0.2 to 100.7 and from 0.4 to 104.5 mu mol L-1, respectively, with detection limits of 0.08 and 0.2 mu mol L-1, respectively. The practical feasibility of the developed method was demonstrated by quantification of harmaline in the extracts of natural food products such as Syrian rue (Peganum harmala, also known as esphant, harmal, yiizerlik) seeds, locally used as condiment and medicine in Turkey and the Near and Middle East, and the South American shamanic drink component Ayahuasca liane (Banisteriopsis caapi) with results in good agreement with those obtained by high-performance liquid chromatography as a reference method. The proposed sensor represents an effective electrochemical tool and inexpensive alternative for quality control analysis of food products containing harmaline.
PB  - Elsevier Science Sa, Lausanne
T2  - Journal of Electroanalytical Chemistry
T1  - Voltammetric determination of harmaline in natural food products using boron-doped diamond electrode
VL  - 744
SP  - 37
EP  - 44
DO  - 10.1016/j.jelechem.2015.03.004
ER  - 

@article{
author = "Šovrc, Ľubomír and Cinková, Kristína and Samphao, Anchalee and Stanković, Dalibor and Mehmeti, Eda and Kalcher, Kurt",
year = "2015",
abstract = "A novel analytical approach for the sensitive determination of a beta-carboline alkaloid, harmaline, was developed using pulse voltammetric techniques with a boron-doped diamond electrode. Cyclic voltammetry showed two irreversible oxidation peaks at about +0.90 and +1.20 V (vs. Ag/AgCl) in Britton-Robinson buffer solution at pH 5. Under optimized experimental conditions, differential pulse and square-wave voltammetry were elaborated for the determination of harmaline in a linear concentration range from 0.2 to 100.7 and from 0.4 to 104.5 mu mol L-1, respectively, with detection limits of 0.08 and 0.2 mu mol L-1, respectively. The practical feasibility of the developed method was demonstrated by quantification of harmaline in the extracts of natural food products such as Syrian rue (Peganum harmala, also known as esphant, harmal, yiizerlik) seeds, locally used as condiment and medicine in Turkey and the Near and Middle East, and the South American shamanic drink component Ayahuasca liane (Banisteriopsis caapi) with results in good agreement with those obtained by high-performance liquid chromatography as a reference method. The proposed sensor represents an effective electrochemical tool and inexpensive alternative for quality control analysis of food products containing harmaline.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Journal of Electroanalytical Chemistry",
title = "Voltammetric determination of harmaline in natural food products using boron-doped diamond electrode",
volume = "744",
pages = "37-44",
doi = "10.1016/j.jelechem.2015.03.004"
}

Šovrc, Ľ., Cinková, K., Samphao, A., Stanković, D., Mehmeti, E.,& Kalcher, K.. (2015). Voltammetric determination of harmaline in natural food products using boron-doped diamond electrode. in Journal of Electroanalytical Chemistry
Elsevier Science Sa, Lausanne., 744, 37-44.
https://doi.org/10.1016/j.jelechem.2015.03.004

Šovrc Ľ, Cinková K, Samphao A, Stanković D, Mehmeti E, Kalcher K. Voltammetric determination of harmaline in natural food products using boron-doped diamond electrode. in Journal of Electroanalytical Chemistry. 2015;744:37-44.
doi:10.1016/j.jelechem.2015.03.004 .

Šovrc, Ľubomír, Cinková, Kristína, Samphao, Anchalee, Stanković, Dalibor, Mehmeti, Eda, Kalcher, Kurt, "Voltammetric determination of harmaline in natural food products using boron-doped diamond electrode" in Journal of Electroanalytical Chemistry, 744 (2015):37-44,
https://doi.org/10.1016/j.jelechem.2015.03.004 . .