TY  - DATA
AU  - Zengin, Gokhan
AU  - Cvetanović, Aleksandra
AU  - Gašić, Uroš M.
AU  - Tešić, Živoslav Lj.
AU  - Stupar, Alena
AU  - Bulut, Gizem
AU  - Sinan, Kouadio Ibrahime
AU  - Uysal, Sengul
AU  - Picot-Allain, Marie Carene Nancy
AU  - Mahomoodally, Mohamad Fawzi
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3965
PB  - Elsevier
T2  - Process Biochemistry
T1  - Supplementary data for the article: Zengin, G.; Cvetanović, A.; Gašić, U.; Tešić, Ž.; Stupar, A.; Bulut, G.; Sinan, K. I.; Uysal, S.; Picot-Allain, M. C. N.; Mahomoodally, M. F. A Comparative Exploration of the Phytochemical Profiles and Bio-Pharmaceutical Potential of Helichrysum Stoechas Subsp. Barrelieri Extracts Obtained via Five Extraction Techniques. Process Biochemistry 2020, 91, 113–125. https://doi.org/10.1016/j.procbio.2019.12.002
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3965
ER  - 

@misc{
author = "Zengin, Gokhan and Cvetanović, Aleksandra and Gašić, Uroš M. and Tešić, Živoslav Lj. and Stupar, Alena and Bulut, Gizem and Sinan, Kouadio Ibrahime and Uysal, Sengul and Picot-Allain, Marie Carene Nancy and Mahomoodally, Mohamad Fawzi",
year = "2020",
publisher = "Elsevier",
journal = "Process Biochemistry",
title = "Supplementary data for the article: Zengin, G.; Cvetanović, A.; Gašić, U.; Tešić, Ž.; Stupar, A.; Bulut, G.; Sinan, K. I.; Uysal, S.; Picot-Allain, M. C. N.; Mahomoodally, M. F. A Comparative Exploration of the Phytochemical Profiles and Bio-Pharmaceutical Potential of Helichrysum Stoechas Subsp. Barrelieri Extracts Obtained via Five Extraction Techniques. Process Biochemistry 2020, 91, 113–125. https://doi.org/10.1016/j.procbio.2019.12.002",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3965"
}

Zengin, G., Cvetanović, A., Gašić, U. M., Tešić, Ž. Lj., Stupar, A., Bulut, G., Sinan, K. I., Uysal, S., Picot-Allain, M. C. N.,& Mahomoodally, M. F.. (2020). Supplementary data for the article: Zengin, G.; Cvetanović, A.; Gašić, U.; Tešić, Ž.; Stupar, A.; Bulut, G.; Sinan, K. I.; Uysal, S.; Picot-Allain, M. C. N.; Mahomoodally, M. F. A Comparative Exploration of the Phytochemical Profiles and Bio-Pharmaceutical Potential of Helichrysum Stoechas Subsp. Barrelieri Extracts Obtained via Five Extraction Techniques. Process Biochemistry 2020, 91, 113–125. https://doi.org/10.1016/j.procbio.2019.12.002. in Process Biochemistry
Elsevier..
https://hdl.handle.net/21.15107/rcub_cherry_3965

Zengin G, Cvetanović A, Gašić UM, Tešić ŽL, Stupar A, Bulut G, Sinan KI, Uysal S, Picot-Allain MCN, Mahomoodally MF. Supplementary data for the article: Zengin, G.; Cvetanović, A.; Gašić, U.; Tešić, Ž.; Stupar, A.; Bulut, G.; Sinan, K. I.; Uysal, S.; Picot-Allain, M. C. N.; Mahomoodally, M. F. A Comparative Exploration of the Phytochemical Profiles and Bio-Pharmaceutical Potential of Helichrysum Stoechas Subsp. Barrelieri Extracts Obtained via Five Extraction Techniques. Process Biochemistry 2020, 91, 113–125. https://doi.org/10.1016/j.procbio.2019.12.002. in Process Biochemistry. 2020;.
https://hdl.handle.net/21.15107/rcub_cherry_3965 .

Zengin, Gokhan, Cvetanović, Aleksandra, Gašić, Uroš M., Tešić, Živoslav Lj., Stupar, Alena, Bulut, Gizem, Sinan, Kouadio Ibrahime, Uysal, Sengul, Picot-Allain, Marie Carene Nancy, Mahomoodally, Mohamad Fawzi, "Supplementary data for the article: Zengin, G.; Cvetanović, A.; Gašić, U.; Tešić, Ž.; Stupar, A.; Bulut, G.; Sinan, K. I.; Uysal, S.; Picot-Allain, M. C. N.; Mahomoodally, M. F. A Comparative Exploration of the Phytochemical Profiles and Bio-Pharmaceutical Potential of Helichrysum Stoechas Subsp. Barrelieri Extracts Obtained via Five Extraction Techniques. Process Biochemistry 2020, 91, 113–125. https://doi.org/10.1016/j.procbio.2019.12.002" in Process Biochemistry (2020),
https://hdl.handle.net/21.15107/rcub_cherry_3965 .

TY  - JOUR
AU  - Zengin, Gokhan
AU  - Cvetanović, Aleksandra
AU  - Gašić, Uroš M.
AU  - Stupar, Alena
AU  - Bulut, Gizem
AU  - Şenkardes, Ismail
AU  - Dogan, Ahmet
AU  - Ibrahime Sinan, Kouadio
AU  - Uysal, Sengul
AU  - Aumeeruddy-Elalfi, Zaahira
AU  - Aktumsek, Abdurrahman
AU  - Fawzi Mahomoodally, Mohamad
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3882
AB  - Tanacetum parthenium (L.) Sch.Bip (TP), a flowering plant, is famous in traditional medicine to prevent migraine and headache. However, there is currently a dearth of studies to advocate the phytochemical profile and biological propensities of extracts prepared from this plant. This study endeavors to highlight the biological potential of TP extracts prepared by modern (ultrasound-UAE, microwave-MAE and accelerated-ASE extractions) and traditional (maceration and Soxhlet) extraction techniques. The chemical profile of the extracts was established via ultra-high-pressure liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) technique. Sixty different polyphenolic compounds belonging to the classes of phenolic acids, flavonoid glycosides and flavonoid aglycones were recorded in the extracts. Additionally, the quantity of 17 components was measured using appropriate standards and it was found that the modern extraction gave extracts with the higher content of observed compounds than the traditional techniques. Evaluation of antioxidant activity was determined in vitro via five standard assays. The inhibitory potential of TP extracts against key enzymes implicated in the non-communicable diseases such as diabetes (α-amylase and α-glucosidase), neurodegenerative diseases (acetyl- and butyrylcholinesterase) and skin diseases (tyrosinase), was assessed. Potent antioxidant ability of all TP extract was revealed with a predominance for the extracts yielded using the ASE method. This potent antioxidant activity of the extracts corroborated with the high phenolic (65.05 ± 0.27 mg gallic acid equivalent (GAE)/g extract) and flavonoid contents (55.40 ± 0.52 mg rutin equivalent (RE)/g extract). Tanacetum parthenium extracts also showed significant α-glucosidase inhibitory activity (1.63–1.67 mmol acarbose equivalent (ACAE)/g extract) and moderate inhibition activity against α-amylase (0.51-0.56 mmol ACAE/g extract). The extracts also showed potent activity against cholinesterases and tyrosinase. This study tend to validate the use of TP extracts obtained by novel extraction techniques such as ASE, as potent bioactive extracts to be further studied for therapeutic bio-product development.
PB  - Elsevier
T2  - Industrial Crops and Products
T1  - Modern and traditional extraction techniques affect chemical composition and bioactivity of Tanacetum parthenium (L.) Sch.Bip
VL  - 146
DO  - 10.1016/j.indcrop.2020.112202
ER  - 

@article{
author = "Zengin, Gokhan and Cvetanović, Aleksandra and Gašić, Uroš M. and Stupar, Alena and Bulut, Gizem and Şenkardes, Ismail and Dogan, Ahmet and Ibrahime Sinan, Kouadio and Uysal, Sengul and Aumeeruddy-Elalfi, Zaahira and Aktumsek, Abdurrahman and Fawzi Mahomoodally, Mohamad",
year = "2020",
abstract = "Tanacetum parthenium (L.) Sch.Bip (TP), a flowering plant, is famous in traditional medicine to prevent migraine and headache. However, there is currently a dearth of studies to advocate the phytochemical profile and biological propensities of extracts prepared from this plant. This study endeavors to highlight the biological potential of TP extracts prepared by modern (ultrasound-UAE, microwave-MAE and accelerated-ASE extractions) and traditional (maceration and Soxhlet) extraction techniques. The chemical profile of the extracts was established via ultra-high-pressure liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) technique. Sixty different polyphenolic compounds belonging to the classes of phenolic acids, flavonoid glycosides and flavonoid aglycones were recorded in the extracts. Additionally, the quantity of 17 components was measured using appropriate standards and it was found that the modern extraction gave extracts with the higher content of observed compounds than the traditional techniques. Evaluation of antioxidant activity was determined in vitro via five standard assays. The inhibitory potential of TP extracts against key enzymes implicated in the non-communicable diseases such as diabetes (α-amylase and α-glucosidase), neurodegenerative diseases (acetyl- and butyrylcholinesterase) and skin diseases (tyrosinase), was assessed. Potent antioxidant ability of all TP extract was revealed with a predominance for the extracts yielded using the ASE method. This potent antioxidant activity of the extracts corroborated with the high phenolic (65.05 ± 0.27 mg gallic acid equivalent (GAE)/g extract) and flavonoid contents (55.40 ± 0.52 mg rutin equivalent (RE)/g extract). Tanacetum parthenium extracts also showed significant α-glucosidase inhibitory activity (1.63–1.67 mmol acarbose equivalent (ACAE)/g extract) and moderate inhibition activity against α-amylase (0.51-0.56 mmol ACAE/g extract). The extracts also showed potent activity against cholinesterases and tyrosinase. This study tend to validate the use of TP extracts obtained by novel extraction techniques such as ASE, as potent bioactive extracts to be further studied for therapeutic bio-product development.",
publisher = "Elsevier",
journal = "Industrial Crops and Products",
title = "Modern and traditional extraction techniques affect chemical composition and bioactivity of Tanacetum parthenium (L.) Sch.Bip",
volume = "146",
doi = "10.1016/j.indcrop.2020.112202"
}

Zengin, G., Cvetanović, A., Gašić, U. M., Stupar, A., Bulut, G., Şenkardes, I., Dogan, A., Ibrahime Sinan, K., Uysal, S., Aumeeruddy-Elalfi, Z., Aktumsek, A.,& Fawzi Mahomoodally, M.. (2020). Modern and traditional extraction techniques affect chemical composition and bioactivity of Tanacetum parthenium (L.) Sch.Bip. in Industrial Crops and Products
Elsevier., 146.
https://doi.org/10.1016/j.indcrop.2020.112202

Zengin G, Cvetanović A, Gašić UM, Stupar A, Bulut G, Şenkardes I, Dogan A, Ibrahime Sinan K, Uysal S, Aumeeruddy-Elalfi Z, Aktumsek A, Fawzi Mahomoodally M. Modern and traditional extraction techniques affect chemical composition and bioactivity of Tanacetum parthenium (L.) Sch.Bip. in Industrial Crops and Products. 2020;146.
doi:10.1016/j.indcrop.2020.112202 .

Zengin, Gokhan, Cvetanović, Aleksandra, Gašić, Uroš M., Stupar, Alena, Bulut, Gizem, Şenkardes, Ismail, Dogan, Ahmet, Ibrahime Sinan, Kouadio, Uysal, Sengul, Aumeeruddy-Elalfi, Zaahira, Aktumsek, Abdurrahman, Fawzi Mahomoodally, Mohamad, "Modern and traditional extraction techniques affect chemical composition and bioactivity of Tanacetum parthenium (L.) Sch.Bip" in Industrial Crops and Products, 146 (2020),
https://doi.org/10.1016/j.indcrop.2020.112202 . .

TY  - DATA
AU  - Zengin, Gokhan
AU  - Cvetanović, Aleksandra
AU  - Gašić, Uroš M.
AU  - Stupar, Alena
AU  - Bulut, Gizem
AU  - Şenkardes, Ismail
AU  - Dogan, Ahmet
AU  - Ibrahime Sinan, Kouadio
AU  - Uysal, Sengul
AU  - Aumeeruddy-Elalfi, Zaahira
AU  - Aktumsek, Abdurrahman
AU  - Fawzi Mahomoodally, Mohamad
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3893
PB  - Elsevier
T2  - Industrial Crops and Products
T1  - Supplementary data for the article: Zengin, G.; Cvetanović, A.; Gašić, U. M.; Stupar, A.; Bulut, G.; Şenkardes, I.; Dogan, A.; Ibrahime Sinan, K.; Uysal, S.; Aumeeruddy-Elalfi, Z.; Aktumsek, A.; Fawzi Mahomoodally, M. Modern and Traditional Extraction Techniques Affect Chemical Composition and Bioactivity of Tanacetum Parthenium (L.) Sch.Bip. Industrial Crops and Products 2020, 146. https://doi.org/10.1016/j.indcrop.2020.112202
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3893
ER  - 

@misc{
author = "Zengin, Gokhan and Cvetanović, Aleksandra and Gašić, Uroš M. and Stupar, Alena and Bulut, Gizem and Şenkardes, Ismail and Dogan, Ahmet and Ibrahime Sinan, Kouadio and Uysal, Sengul and Aumeeruddy-Elalfi, Zaahira and Aktumsek, Abdurrahman and Fawzi Mahomoodally, Mohamad",
year = "2020",
publisher = "Elsevier",
journal = "Industrial Crops and Products",
title = "Supplementary data for the article: Zengin, G.; Cvetanović, A.; Gašić, U. M.; Stupar, A.; Bulut, G.; Şenkardes, I.; Dogan, A.; Ibrahime Sinan, K.; Uysal, S.; Aumeeruddy-Elalfi, Z.; Aktumsek, A.; Fawzi Mahomoodally, M. Modern and Traditional Extraction Techniques Affect Chemical Composition and Bioactivity of Tanacetum Parthenium (L.) Sch.Bip. Industrial Crops and Products 2020, 146. https://doi.org/10.1016/j.indcrop.2020.112202",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3893"
}

Zengin, G., Cvetanović, A., Gašić, U. M., Stupar, A., Bulut, G., Şenkardes, I., Dogan, A., Ibrahime Sinan, K., Uysal, S., Aumeeruddy-Elalfi, Z., Aktumsek, A.,& Fawzi Mahomoodally, M.. (2020). Supplementary data for the article: Zengin, G.; Cvetanović, A.; Gašić, U. M.; Stupar, A.; Bulut, G.; Şenkardes, I.; Dogan, A.; Ibrahime Sinan, K.; Uysal, S.; Aumeeruddy-Elalfi, Z.; Aktumsek, A.; Fawzi Mahomoodally, M. Modern and Traditional Extraction Techniques Affect Chemical Composition and Bioactivity of Tanacetum Parthenium (L.) Sch.Bip. Industrial Crops and Products 2020, 146. https://doi.org/10.1016/j.indcrop.2020.112202. in Industrial Crops and Products
Elsevier..
https://hdl.handle.net/21.15107/rcub_cherry_3893

Zengin G, Cvetanović A, Gašić UM, Stupar A, Bulut G, Şenkardes I, Dogan A, Ibrahime Sinan K, Uysal S, Aumeeruddy-Elalfi Z, Aktumsek A, Fawzi Mahomoodally M. Supplementary data for the article: Zengin, G.; Cvetanović, A.; Gašić, U. M.; Stupar, A.; Bulut, G.; Şenkardes, I.; Dogan, A.; Ibrahime Sinan, K.; Uysal, S.; Aumeeruddy-Elalfi, Z.; Aktumsek, A.; Fawzi Mahomoodally, M. Modern and Traditional Extraction Techniques Affect Chemical Composition and Bioactivity of Tanacetum Parthenium (L.) Sch.Bip. Industrial Crops and Products 2020, 146. https://doi.org/10.1016/j.indcrop.2020.112202. in Industrial Crops and Products. 2020;.
https://hdl.handle.net/21.15107/rcub_cherry_3893 .

Zengin, Gokhan, Cvetanović, Aleksandra, Gašić, Uroš M., Stupar, Alena, Bulut, Gizem, Şenkardes, Ismail, Dogan, Ahmet, Ibrahime Sinan, Kouadio, Uysal, Sengul, Aumeeruddy-Elalfi, Zaahira, Aktumsek, Abdurrahman, Fawzi Mahomoodally, Mohamad, "Supplementary data for the article: Zengin, G.; Cvetanović, A.; Gašić, U. M.; Stupar, A.; Bulut, G.; Şenkardes, I.; Dogan, A.; Ibrahime Sinan, K.; Uysal, S.; Aumeeruddy-Elalfi, Z.; Aktumsek, A.; Fawzi Mahomoodally, M. Modern and Traditional Extraction Techniques Affect Chemical Composition and Bioactivity of Tanacetum Parthenium (L.) Sch.Bip. Industrial Crops and Products 2020, 146. https://doi.org/10.1016/j.indcrop.2020.112202" in Industrial Crops and Products (2020),
https://hdl.handle.net/21.15107/rcub_cherry_3893 .

TY  - JOUR
AU  - Zengin, Gokhan
AU  - Cvetanović, Aleksandra
AU  - Gašić, Uroš M.
AU  - Tešić, Živoslav Lj.
AU  - Stupar, Alena
AU  - Bulut, Gizem
AU  - Sinan, Kouadio Ibrahime
AU  - Uysal, Sengul
AU  - Picot-Allain, Marie Carene Nancy
AU  - Mahomoodally, Mohamad Fawzi
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3963
AB  - We endeavoured to probe into and compare the possible effect(s) of different extraction techniques (accelerated solvent extraction (ASE), microwave-assisted extraction (MAE), ultrasonication-assisted extraction (UAE), maceration, and Soxhlet extraction (SE)) on the bioactivity (antioxidant and enzyme inhibitory activities) of the aerial parts of Helichrysum stoechas subsp. barrelieri (Ten.) Nyman. Total phenolic and flavonoid contents of the extracts obtained by different extraction methods followed the order of ASE > MAE > UAE > maceration > SE. Extract obtained by ASE was the most potent radical scavenger (219.92 and 313.12 mg Trolox equivalent [TE]/g, against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS), respectively) and reducing agent (927.39 and 662.87 mg TE/g, for cupric reducing antioxidant capacity (CUPRAC) and ferric reducing antioxidant power (FRAP), respectively). Helichrysum stoechas extract obtained by UAE (18.67 mg ethylenediaminetetraacetic equivalent [EDTAE]/g) was the most active metal chelator and inhibitor of acetylcholinesterase (4.23 mg galantamine equivalent [GALAE]/g) and butyrylcholinesterase (6.05 mg GALAE/g) cholinesterase. Extract from maceration (183.32 mg kojic acid equivalent [KAE]/g) was most active against tyrosinase while ASE extract (1.66 mmol acarbose equivalent [ACAE]/g) effectively inhibited α-glucosidase. In conclusion, data amassed herein tend to advocate for the use of non-conventional extraction techniques, namely ASE and UAE, for the extraction of bioactive secondary metabolites from H. stoechas aerial parts.
PB  - Elsevier
T2  - Process Biochemistry
T1  - A comparative exploration of the phytochemical profiles and bio-pharmaceutical potential of Helichrysum stoechas subsp. barrelieri extracts obtained via five extraction techniques
VL  - 91
SP  - 113
EP  - 125
DO  - 10.1016/j.procbio.2019.12.002
ER  - 

@article{
author = "Zengin, Gokhan and Cvetanović, Aleksandra and Gašić, Uroš M. and Tešić, Živoslav Lj. and Stupar, Alena and Bulut, Gizem and Sinan, Kouadio Ibrahime and Uysal, Sengul and Picot-Allain, Marie Carene Nancy and Mahomoodally, Mohamad Fawzi",
year = "2020",
abstract = "We endeavoured to probe into and compare the possible effect(s) of different extraction techniques (accelerated solvent extraction (ASE), microwave-assisted extraction (MAE), ultrasonication-assisted extraction (UAE), maceration, and Soxhlet extraction (SE)) on the bioactivity (antioxidant and enzyme inhibitory activities) of the aerial parts of Helichrysum stoechas subsp. barrelieri (Ten.) Nyman. Total phenolic and flavonoid contents of the extracts obtained by different extraction methods followed the order of ASE > MAE > UAE > maceration > SE. Extract obtained by ASE was the most potent radical scavenger (219.92 and 313.12 mg Trolox equivalent [TE]/g, against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS), respectively) and reducing agent (927.39 and 662.87 mg TE/g, for cupric reducing antioxidant capacity (CUPRAC) and ferric reducing antioxidant power (FRAP), respectively). Helichrysum stoechas extract obtained by UAE (18.67 mg ethylenediaminetetraacetic equivalent [EDTAE]/g) was the most active metal chelator and inhibitor of acetylcholinesterase (4.23 mg galantamine equivalent [GALAE]/g) and butyrylcholinesterase (6.05 mg GALAE/g) cholinesterase. Extract from maceration (183.32 mg kojic acid equivalent [KAE]/g) was most active against tyrosinase while ASE extract (1.66 mmol acarbose equivalent [ACAE]/g) effectively inhibited α-glucosidase. In conclusion, data amassed herein tend to advocate for the use of non-conventional extraction techniques, namely ASE and UAE, for the extraction of bioactive secondary metabolites from H. stoechas aerial parts.",
publisher = "Elsevier",
journal = "Process Biochemistry",
title = "A comparative exploration of the phytochemical profiles and bio-pharmaceutical potential of Helichrysum stoechas subsp. barrelieri extracts obtained via five extraction techniques",
volume = "91",
pages = "113-125",
doi = "10.1016/j.procbio.2019.12.002"
}

Zengin, G., Cvetanović, A., Gašić, U. M., Tešić, Ž. Lj., Stupar, A., Bulut, G., Sinan, K. I., Uysal, S., Picot-Allain, M. C. N.,& Mahomoodally, M. F.. (2020). A comparative exploration of the phytochemical profiles and bio-pharmaceutical potential of Helichrysum stoechas subsp. barrelieri extracts obtained via five extraction techniques. in Process Biochemistry
Elsevier., 91, 113-125.
https://doi.org/10.1016/j.procbio.2019.12.002

Zengin G, Cvetanović A, Gašić UM, Tešić ŽL, Stupar A, Bulut G, Sinan KI, Uysal S, Picot-Allain MCN, Mahomoodally MF. A comparative exploration of the phytochemical profiles and bio-pharmaceutical potential of Helichrysum stoechas subsp. barrelieri extracts obtained via five extraction techniques. in Process Biochemistry. 2020;91:113-125.
doi:10.1016/j.procbio.2019.12.002 .

Zengin, Gokhan, Cvetanović, Aleksandra, Gašić, Uroš M., Tešić, Živoslav Lj., Stupar, Alena, Bulut, Gizem, Sinan, Kouadio Ibrahime, Uysal, Sengul, Picot-Allain, Marie Carene Nancy, Mahomoodally, Mohamad Fawzi, "A comparative exploration of the phytochemical profiles and bio-pharmaceutical potential of Helichrysum stoechas subsp. barrelieri extracts obtained via five extraction techniques" in Process Biochemistry, 91 (2020):113-125,
https://doi.org/10.1016/j.procbio.2019.12.002 . .

TY  - JOUR
AU  - Zengin, Gokhan
AU  - Cvetanović, Aleksandra
AU  - Gašić, Uroš M.
AU  - Tešić, Živoslav Lj.
AU  - Stupar, Alena
AU  - Bulut, Gizem
AU  - Sinan, Kouadio Ibrahime
AU  - Uysal, Sengul
AU  - Picot-Allain, Marie Carene Nancy
AU  - Mahomoodally, Mohamad Fawzi
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3964
AB  - We endeavoured to probe into and compare the possible effect(s) of different extraction techniques (accelerated solvent extraction (ASE), microwave-assisted extraction (MAE), ultrasonication-assisted extraction (UAE), maceration, and Soxhlet extraction (SE)) on the bioactivity (antioxidant and enzyme inhibitory activities) of the aerial parts of Helichrysum stoechas subsp. barrelieri (Ten.) Nyman. Total phenolic and flavonoid contents of the extracts obtained by different extraction methods followed the order of ASE > MAE > UAE > maceration > SE. Extract obtained by ASE was the most potent radical scavenger (219.92 and 313.12 mg Trolox equivalent [TE]/g, against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS), respectively) and reducing agent (927.39 and 662.87 mg TE/g, for cupric reducing antioxidant capacity (CUPRAC) and ferric reducing antioxidant power (FRAP), respectively). Helichrysum stoechas extract obtained by UAE (18.67 mg ethylenediaminetetraacetic equivalent [EDTAE]/g) was the most active metal chelator and inhibitor of acetylcholinesterase (4.23 mg galantamine equivalent [GALAE]/g) and butyrylcholinesterase (6.05 mg GALAE/g) cholinesterase. Extract from maceration (183.32 mg kojic acid equivalent [KAE]/g) was most active against tyrosinase while ASE extract (1.66 mmol acarbose equivalent [ACAE]/g) effectively inhibited α-glucosidase. In conclusion, data amassed herein tend to advocate for the use of non-conventional extraction techniques, namely ASE and UAE, for the extraction of bioactive secondary metabolites from H. stoechas aerial parts.
PB  - Elsevier
T2  - Process Biochemistry
T1  - A comparative exploration of the phytochemical profiles and bio-pharmaceutical potential of Helichrysum stoechas subsp. barrelieri extracts obtained via five extraction techniques
VL  - 91
SP  - 113
EP  - 125
DO  - 10.1016/j.procbio.2019.12.002
ER  - 

@article{
author = "Zengin, Gokhan and Cvetanović, Aleksandra and Gašić, Uroš M. and Tešić, Živoslav Lj. and Stupar, Alena and Bulut, Gizem and Sinan, Kouadio Ibrahime and Uysal, Sengul and Picot-Allain, Marie Carene Nancy and Mahomoodally, Mohamad Fawzi",
year = "2020",
abstract = "We endeavoured to probe into and compare the possible effect(s) of different extraction techniques (accelerated solvent extraction (ASE), microwave-assisted extraction (MAE), ultrasonication-assisted extraction (UAE), maceration, and Soxhlet extraction (SE)) on the bioactivity (antioxidant and enzyme inhibitory activities) of the aerial parts of Helichrysum stoechas subsp. barrelieri (Ten.) Nyman. Total phenolic and flavonoid contents of the extracts obtained by different extraction methods followed the order of ASE > MAE > UAE > maceration > SE. Extract obtained by ASE was the most potent radical scavenger (219.92 and 313.12 mg Trolox equivalent [TE]/g, against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS), respectively) and reducing agent (927.39 and 662.87 mg TE/g, for cupric reducing antioxidant capacity (CUPRAC) and ferric reducing antioxidant power (FRAP), respectively). Helichrysum stoechas extract obtained by UAE (18.67 mg ethylenediaminetetraacetic equivalent [EDTAE]/g) was the most active metal chelator and inhibitor of acetylcholinesterase (4.23 mg galantamine equivalent [GALAE]/g) and butyrylcholinesterase (6.05 mg GALAE/g) cholinesterase. Extract from maceration (183.32 mg kojic acid equivalent [KAE]/g) was most active against tyrosinase while ASE extract (1.66 mmol acarbose equivalent [ACAE]/g) effectively inhibited α-glucosidase. In conclusion, data amassed herein tend to advocate for the use of non-conventional extraction techniques, namely ASE and UAE, for the extraction of bioactive secondary metabolites from H. stoechas aerial parts.",
publisher = "Elsevier",
journal = "Process Biochemistry",
title = "A comparative exploration of the phytochemical profiles and bio-pharmaceutical potential of Helichrysum stoechas subsp. barrelieri extracts obtained via five extraction techniques",
volume = "91",
pages = "113-125",
doi = "10.1016/j.procbio.2019.12.002"
}

Zengin, G., Cvetanović, A., Gašić, U. M., Tešić, Ž. Lj., Stupar, A., Bulut, G., Sinan, K. I., Uysal, S., Picot-Allain, M. C. N.,& Mahomoodally, M. F.. (2020). A comparative exploration of the phytochemical profiles and bio-pharmaceutical potential of Helichrysum stoechas subsp. barrelieri extracts obtained via five extraction techniques. in Process Biochemistry
Elsevier., 91, 113-125.
https://doi.org/10.1016/j.procbio.2019.12.002

Zengin G, Cvetanović A, Gašić UM, Tešić ŽL, Stupar A, Bulut G, Sinan KI, Uysal S, Picot-Allain MCN, Mahomoodally MF. A comparative exploration of the phytochemical profiles and bio-pharmaceutical potential of Helichrysum stoechas subsp. barrelieri extracts obtained via five extraction techniques. in Process Biochemistry. 2020;91:113-125.
doi:10.1016/j.procbio.2019.12.002 .

Zengin, Gokhan, Cvetanović, Aleksandra, Gašić, Uroš M., Tešić, Živoslav Lj., Stupar, Alena, Bulut, Gizem, Sinan, Kouadio Ibrahime, Uysal, Sengul, Picot-Allain, Marie Carene Nancy, Mahomoodally, Mohamad Fawzi, "A comparative exploration of the phytochemical profiles and bio-pharmaceutical potential of Helichrysum stoechas subsp. barrelieri extracts obtained via five extraction techniques" in Process Biochemistry, 91 (2020):113-125,
https://doi.org/10.1016/j.procbio.2019.12.002 . .