Spasić, Snežana

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Authority KeyName Variants
orcid::0000-0003-1731-3508
  • Spasić, Snežana (27)
Projects
Strengthening of the MagBioVin Research and Innovation Team for Development of Novel Approaches for Tumour Therapy based on Nanostructured Materials Molecular mechanisms of redox signalling in homeostasis: adaptation and pathology
Simultaneous Bioremediation and Soilification of Degraded Areas to Preserve Natural Resources of Biologically Active Substances, and Development and Production of Biomaterials and Dietetic Products FoodEnTwin-Twinning of research activities for the frontier research in the fields of food, nutrition and environmental omics
Allergens, antibodies, enzymes and small physiologically important molecules: design, structure, function and relevance Study of structure-function relationships in the plant cell wall and modifications of the wall structure by enzyme engineering
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200026 (University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM) Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200168 (University of Belgrade, Faculty of Chemistry)
Modulation of antioxidative metabolism in plants for improvement of plant abiotic stress tolerance and identification of new biomarkers for application in remediation and monitoring of degraded biotopes Application of advanced oxidation processes and nanostructured oxide materials for the removal of pollutants from the environment, development and optimisation of instrumental techniques for efficiency monitoring
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200007 (University of Belgrade, Institute for Biological Research 'Siniša Stanković') Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200051 (Institute of General and Physical Chemistry, Belgrade)
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200178 (University of Belgrade, Faculty of Biology) Proizvodni mobilni bioreaktor i dobijanje biomase mikroorganizama za bioremedijaciju
The Ministry of Science and Environmental Protection of Serbia under project no. 7032B

Author's Bibliography

Effects of several atypical antipsychotics closapine, sertindole or ziprasidone on hepatic antioxidant enzymes: Possible role in drug-induced liver dysfunction

Platanić Arizanović, Lena; Nikolić-Kokić, Aleksandra; Brkljačić, Jelena; Tatalović, Nikola; Miler, Marko; Oreščanin-Dušić, Zorana; Vidonja Uzelac, Teodora; Nikolić, Milan; Milošević, Verica; Blagojević, Duško P.; Spasić, Snežana; Miljević, Čedo

(Taylor and Francis, 2021)

TY  - JOUR
AU  - Platanić Arizanović, Lena
AU  - Nikolić-Kokić, Aleksandra
AU  - Brkljačić, Jelena
AU  - Tatalović, Nikola
AU  - Miler, Marko
AU  - Oreščanin-Dušić, Zorana
AU  - Vidonja Uzelac, Teodora
AU  - Nikolić, Milan
AU  - Milošević, Verica
AU  - Blagojević, Duško P.
AU  - Spasić, Snežana
AU  - Miljević, Čedo
PY  - 2021
UR  - http://www.ncbi.nlm.nih.gov/pubmed/33234086
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4778
AB  - Chronic use of atypical antipsychotics may produce hepatic damage. Atypical antipsychotics, including clozapine, sertindole, and ziprasidone, are extensively metabolized by the liver and this process generates toxic-free radical metabolic intermediates which may contribute to liver damage. The aim of this study was to investigate whether clozapine, sertindole, or ziprasidone affected hepatic antioxidant defense enzymes which consequently led to disturbed redox homeostasis. The expression and activity of antioxidant enzymes superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase (GR), catalase (CAT), and glutathione-S-transferases (GST) were measured in rat livers at doses corresponding to human antipsychotic therapy. Clozapine increased activity of SOD types 1 and 2, GR and GST, but reduced CAT activity. Sertindole elevated activities of both SODs. In ziprasidone-treated rats only decreased CAT activity was found. All three antipsychotics produced mild-to-moderate hepatic histopathological changes categorized as regenerative alterations. No apparent signs of immune cell infiltration, microvesicular or macrovesicular fatty change, or hepatocytes in mitosis were observed. In conclusion, a 4-week long daily treatment with clozapine, sertindole, or ziprasidone altered hepatic antioxidant enzyme activities and induced histopathological changes in liver. The most severe alterations were noted in clozapine-treated rats. Data indicate that redox disturbances may contribute to liver dysfunction after long-term atypical antipsychotic drug treatment.
PB  - Taylor and Francis
T2  - Journal of Toxicology and Environmental Health. Part A
T2  - Journal of Toxicology and Environmental Health. Part AJ Toxicol Environ Health A
T1  - Effects of several atypical antipsychotics closapine, sertindole or ziprasidone on hepatic antioxidant enzymes: Possible role in drug-induced liver dysfunction
VL  - 84
IS  - 4
SP  - 173
EP  - 182
DO  - 10.1080/15287394.2020.1844827
ER  - 
@article{
author = "Platanić Arizanović, Lena and Nikolić-Kokić, Aleksandra and Brkljačić, Jelena and Tatalović, Nikola and Miler, Marko and Oreščanin-Dušić, Zorana and Vidonja Uzelac, Teodora and Nikolić, Milan and Milošević, Verica and Blagojević, Duško P. and Spasić, Snežana and Miljević, Čedo",
year = "2021",
abstract = "Chronic use of atypical antipsychotics may produce hepatic damage. Atypical antipsychotics, including clozapine, sertindole, and ziprasidone, are extensively metabolized by the liver and this process generates toxic-free radical metabolic intermediates which may contribute to liver damage. The aim of this study was to investigate whether clozapine, sertindole, or ziprasidone affected hepatic antioxidant defense enzymes which consequently led to disturbed redox homeostasis. The expression and activity of antioxidant enzymes superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase (GR), catalase (CAT), and glutathione-S-transferases (GST) were measured in rat livers at doses corresponding to human antipsychotic therapy. Clozapine increased activity of SOD types 1 and 2, GR and GST, but reduced CAT activity. Sertindole elevated activities of both SODs. In ziprasidone-treated rats only decreased CAT activity was found. All three antipsychotics produced mild-to-moderate hepatic histopathological changes categorized as regenerative alterations. No apparent signs of immune cell infiltration, microvesicular or macrovesicular fatty change, or hepatocytes in mitosis were observed. In conclusion, a 4-week long daily treatment with clozapine, sertindole, or ziprasidone altered hepatic antioxidant enzyme activities and induced histopathological changes in liver. The most severe alterations were noted in clozapine-treated rats. Data indicate that redox disturbances may contribute to liver dysfunction after long-term atypical antipsychotic drug treatment.",
publisher = "Taylor and Francis",
journal = "Journal of Toxicology and Environmental Health. Part A, Journal of Toxicology and Environmental Health. Part AJ Toxicol Environ Health A",
title = "Effects of several atypical antipsychotics closapine, sertindole or ziprasidone on hepatic antioxidant enzymes: Possible role in drug-induced liver dysfunction",
volume = "84",
number = "4",
pages = "173-182",
doi = "10.1080/15287394.2020.1844827"
}
Platanić Arizanović, L., Nikolić-Kokić, A., Brkljačić, J., Tatalović, N., Miler, M., Oreščanin-Dušić, Z., Vidonja Uzelac, T., Nikolić, M., Milošević, V., Blagojević, D. P., Spasić, S.,& Miljević, Č.. (2021). Effects of several atypical antipsychotics closapine, sertindole or ziprasidone on hepatic antioxidant enzymes: Possible role in drug-induced liver dysfunction. in Journal of Toxicology and Environmental Health. Part A
Taylor and Francis., 84(4), 173-182.
https://doi.org/10.1080/15287394.2020.1844827
Platanić Arizanović L, Nikolić-Kokić A, Brkljačić J, Tatalović N, Miler M, Oreščanin-Dušić Z, Vidonja Uzelac T, Nikolić M, Milošević V, Blagojević DP, Spasić S, Miljević Č. Effects of several atypical antipsychotics closapine, sertindole or ziprasidone on hepatic antioxidant enzymes: Possible role in drug-induced liver dysfunction. in Journal of Toxicology and Environmental Health. Part A. 2021;84(4):173-182.
doi:10.1080/15287394.2020.1844827 .
Platanić Arizanović, Lena, Nikolić-Kokić, Aleksandra, Brkljačić, Jelena, Tatalović, Nikola, Miler, Marko, Oreščanin-Dušić, Zorana, Vidonja Uzelac, Teodora, Nikolić, Milan, Milošević, Verica, Blagojević, Duško P., Spasić, Snežana, Miljević, Čedo, "Effects of several atypical antipsychotics closapine, sertindole or ziprasidone on hepatic antioxidant enzymes: Possible role in drug-induced liver dysfunction" in Journal of Toxicology and Environmental Health. Part A, 84, no. 4 (2021):173-182,
https://doi.org/10.1080/15287394.2020.1844827 . .
1
1

Investigation of pectin as a prebiotic, antioxidant and antimicrobial agent for the bacteria selected from human milk of mothers of premature infants

Lugonja, Nikoleta; Lončarević, Branka D.; Stanković, Dalibor; Marinković, Vesna S.; Lješević, Marija; Spasić, Snežana; Beškoski, Vladimir

(Turin : Edizioni Minerva Medica, 2021)

TY  - JOUR
AU  - Lugonja, Nikoleta
AU  - Lončarević, Branka D.
AU  - Stanković, Dalibor
AU  - Marinković, Vesna S.
AU  - Lješević, Marija
AU  - Spasić, Snežana
AU  - Beškoski, Vladimir
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4432
AB  - BACKGROUND: Pectin is a complex polysaccharide, present in fresh and processed food as an additive, which also serves as an important source of fiber. In this work, the aim was to investigate in-vitro application of apple pectin as a possible antimicrobial, antioxidant and prebiotic agent for growth of bacteria selected from human milk and infant feces, as well as standard strains Lactobacillus rhamnosus and Bifidobacterium bifidum.
METHODS : All the bacteria isolated from the milk of mothers of preterm and term-born infants, bacteria from infant feces and standard strains were tested for fermentation of apple pectin as the main carbohydrate in selective broth media.
RESULTS: An increase in the growth of bacteria Bifidobacteria, Lactobacillus, and a consortium of bacteria selected from human milk and infant feces was noticed after pectin fermentation. It was found that pectin has a positive impact on the increase of the antioxidant capacity in all the tested samples. A high correlation was achieved, comparing electrochemical with spectrophotometric methods. Antimicrobial tests showed that pectin and fermentation products have slight or no influence at all on the growth of standard strains of Escherichia coli, Staphylococcus aureus and Candida albicans.
CONCLUSIONS: The results showed the importance of pectin as an antioxidant and its impact on the development of potential probiotic microbiota in mothers and infants. The study indicated a new potential application of pectin as a supplement in infant food.
PB  - Turin : Edizioni Minerva Medica
T2  - Minerva Biotechnology and Biomolecular Research
T1  - Investigation of pectin as a prebiotic, antioxidant and antimicrobial agent for the bacteria selected from human milk of mothers of premature infants
VL  - 33
IS  - 2
SP  - 86
EP  - 92
DO  - 10.23736/S2724-542X.21.02760-9
ER  - 
@article{
author = "Lugonja, Nikoleta and Lončarević, Branka D. and Stanković, Dalibor and Marinković, Vesna S. and Lješević, Marija and Spasić, Snežana and Beškoski, Vladimir",
year = "2021",
abstract = "BACKGROUND: Pectin is a complex polysaccharide, present in fresh and processed food as an additive, which also serves as an important source of fiber. In this work, the aim was to investigate in-vitro application of apple pectin as a possible antimicrobial, antioxidant and prebiotic agent for growth of bacteria selected from human milk and infant feces, as well as standard strains Lactobacillus rhamnosus and Bifidobacterium bifidum.
METHODS : All the bacteria isolated from the milk of mothers of preterm and term-born infants, bacteria from infant feces and standard strains were tested for fermentation of apple pectin as the main carbohydrate in selective broth media.
RESULTS: An increase in the growth of bacteria Bifidobacteria, Lactobacillus, and a consortium of bacteria selected from human milk and infant feces was noticed after pectin fermentation. It was found that pectin has a positive impact on the increase of the antioxidant capacity in all the tested samples. A high correlation was achieved, comparing electrochemical with spectrophotometric methods. Antimicrobial tests showed that pectin and fermentation products have slight or no influence at all on the growth of standard strains of Escherichia coli, Staphylococcus aureus and Candida albicans.
CONCLUSIONS: The results showed the importance of pectin as an antioxidant and its impact on the development of potential probiotic microbiota in mothers and infants. The study indicated a new potential application of pectin as a supplement in infant food.",
publisher = "Turin : Edizioni Minerva Medica",
journal = "Minerva Biotechnology and Biomolecular Research",
title = "Investigation of pectin as a prebiotic, antioxidant and antimicrobial agent for the bacteria selected from human milk of mothers of premature infants",
volume = "33",
number = "2",
pages = "86-92",
doi = "10.23736/S2724-542X.21.02760-9"
}
Lugonja, N., Lončarević, B. D., Stanković, D., Marinković, V. S., Lješević, M., Spasić, S.,& Beškoski, V.. (2021). Investigation of pectin as a prebiotic, antioxidant and antimicrobial agent for the bacteria selected from human milk of mothers of premature infants. in Minerva Biotechnology and Biomolecular Research
Turin : Edizioni Minerva Medica., 33(2), 86-92.
https://doi.org/10.23736/S2724-542X.21.02760-9
Lugonja N, Lončarević BD, Stanković D, Marinković VS, Lješević M, Spasić S, Beškoski V. Investigation of pectin as a prebiotic, antioxidant and antimicrobial agent for the bacteria selected from human milk of mothers of premature infants. in Minerva Biotechnology and Biomolecular Research. 2021;33(2):86-92.
doi:10.23736/S2724-542X.21.02760-9 .
Lugonja, Nikoleta, Lončarević, Branka D., Stanković, Dalibor, Marinković, Vesna S., Lješević, Marija, Spasić, Snežana, Beškoski, Vladimir, "Investigation of pectin as a prebiotic, antioxidant and antimicrobial agent for the bacteria selected from human milk of mothers of premature infants" in Minerva Biotechnology and Biomolecular Research, 33, no. 2 (2021):86-92,
https://doi.org/10.23736/S2724-542X.21.02760-9 . .

Antioxidant Capacity and Quality of Human Milk and Infant Formula Determined by Direct Current Polarography

Lugonja, Nikoleta; Gorjanović, Stanislava; Pastor, Ferenc; Marinković, Vesna S.; Miličić, Biljana; Vrvić, Miroslav M.; Spasić, Snežana

(Springer Link, 2021)

TY  - JOUR
AU  - Lugonja, Nikoleta
AU  - Gorjanović, Stanislava
AU  - Pastor, Ferenc
AU  - Marinković, Vesna S.
AU  - Miličić, Biljana
AU  - Vrvić, Miroslav M.
AU  - Spasić, Snežana
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4517
AB  - Antioxidants present in infant food contribute to its nutritive value and provide protection from oxidative damage. Here, a direct current polarographic method, based on a decrease of anodic current from the hydroxoperhydroxo-mercury(II) complex (HPMC) formed at a mercury dropping electrode at its potential of dissolution, was used to determine the total antioxidant capacity (TAC) of infant formulas, human milk collected from mothers of full-term and preterm infants, human milk supplemented with fortifier, and cow milk. TAC of milk samples and infant formula correlated with protein content measured by the Bradford method (Pearson correlation coefficient 0.605, p<0.001), while TAC of human milk correlated with content of free thiol groups measured by the Ellman method (0.779, p<0.001). The results obtained showed that, in contrast to the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, HPMC enables specific insight into the quality of infant milk food which reflects the amounts of free thiol groups and protein content. The significant contribution of milk proteins and the most prevalent amino acids, particularly cysteine, arginine, and phenylalanine, to TAC was shown. Thus, the HPMC method might be useful in monitoring the quality of infant formulas and human milk for preterm infants before and after supplementation with fortifier.
PB  - Springer Link
T2  - Food Analytical Methods
T2  - Food Analytical Methods
T1  - Antioxidant Capacity and Quality of Human Milk and Infant Formula Determined by Direct Current Polarography
VL  - 14
SP  - 1987
EP  - 1994
DO  - 10.1007/s12161-021-02030-3
ER  - 
@article{
author = "Lugonja, Nikoleta and Gorjanović, Stanislava and Pastor, Ferenc and Marinković, Vesna S. and Miličić, Biljana and Vrvić, Miroslav M. and Spasić, Snežana",
year = "2021",
abstract = "Antioxidants present in infant food contribute to its nutritive value and provide protection from oxidative damage. Here, a direct current polarographic method, based on a decrease of anodic current from the hydroxoperhydroxo-mercury(II) complex (HPMC) formed at a mercury dropping electrode at its potential of dissolution, was used to determine the total antioxidant capacity (TAC) of infant formulas, human milk collected from mothers of full-term and preterm infants, human milk supplemented with fortifier, and cow milk. TAC of milk samples and infant formula correlated with protein content measured by the Bradford method (Pearson correlation coefficient 0.605, p<0.001), while TAC of human milk correlated with content of free thiol groups measured by the Ellman method (0.779, p<0.001). The results obtained showed that, in contrast to the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, HPMC enables specific insight into the quality of infant milk food which reflects the amounts of free thiol groups and protein content. The significant contribution of milk proteins and the most prevalent amino acids, particularly cysteine, arginine, and phenylalanine, to TAC was shown. Thus, the HPMC method might be useful in monitoring the quality of infant formulas and human milk for preterm infants before and after supplementation with fortifier.",
publisher = "Springer Link",
journal = "Food Analytical Methods, Food Analytical Methods",
title = "Antioxidant Capacity and Quality of Human Milk and Infant Formula Determined by Direct Current Polarography",
volume = "14",
pages = "1987-1994",
doi = "10.1007/s12161-021-02030-3"
}
Lugonja, N., Gorjanović, S., Pastor, F., Marinković, V. S., Miličić, B., Vrvić, M. M.,& Spasić, S.. (2021). Antioxidant Capacity and Quality of Human Milk and Infant Formula Determined by Direct Current Polarography. in Food Analytical Methods
Springer Link., 14, 1987-1994.
https://doi.org/10.1007/s12161-021-02030-3
Lugonja N, Gorjanović S, Pastor F, Marinković VS, Miličić B, Vrvić MM, Spasić S. Antioxidant Capacity and Quality of Human Milk and Infant Formula Determined by Direct Current Polarography. in Food Analytical Methods. 2021;14:1987-1994.
doi:10.1007/s12161-021-02030-3 .
Lugonja, Nikoleta, Gorjanović, Stanislava, Pastor, Ferenc, Marinković, Vesna S., Miličić, Biljana, Vrvić, Miroslav M., Spasić, Snežana, "Antioxidant Capacity and Quality of Human Milk and Infant Formula Determined by Direct Current Polarography" in Food Analytical Methods, 14 (2021):1987-1994,
https://doi.org/10.1007/s12161-021-02030-3 . .
1
1

Study on the assessment of humification processes during biodegradation of heavy residual fuel oil

Avdalović, Jelena; Miletić, Srđan B.; Božović, Olga; Šolević-Knudsen, Tatjana; Stanković, Dalibor; Lugonja, Nikoleta; Spasić, Snežana; Joksimović, Kristina; Dragičević, Igor; Vrvić, Miroslav M.

(Elsevier, 2021)

TY  - JOUR
AU  - Avdalović, Jelena
AU  - Miletić, Srđan B.
AU  - Božović, Olga
AU  - Šolević-Knudsen, Tatjana
AU  - Stanković, Dalibor
AU  - Lugonja, Nikoleta
AU  - Spasić, Snežana
AU  - Joksimović, Kristina
AU  - Dragičević, Igor
AU  - Vrvić, Miroslav M.
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4608
AB  - The aim of this study was to investigate the creation of humic substances during biodegradation of heavy residual fuel oil, because there are indications that substances similar to humic substances are generated during biodegradation of polycyclic aromatic hydrocarbons. In the study, which lasted for 110 days, biodegradation of heavy residual fuel oil was carried out in a layer of artificial soil substrate. The initial concentration of the total petroleum hydrocarbon in the prepared artificial soil substrate (biopile) was 23.1 g kg-1 dry weight (d.w.). At the end of the process, the total petroleum hydrocarbons were reduced to 8.1 g kg-1 d.w. in the inoculated biopile, while the content of humic acids increased during bioremediation from 3.15 g kg-1 d.w. to 4.95 g kg-1 d.w. The humic acids extracted from biopile during the biodegradation process were characterized by various chemical techniques (elemental analysis, spectrofluorimetric analysis, electrochemical measurements, and size exclusion chromatography). The results showed that levels of C, H and the H/C ratio decreased as the biodegradation process progressed. This indicated that humic acids aromatization process took place and this was confirmed by the spectrofluorimetric analysis. The increase of oxygen percentage and the O/C ratio in the humic acids after the biodegradation treatment indicated an increase in functional oxygen groups. Additional analyses of humic acids from the inoculated biopile showed that they were transformed during the bioremediation process. They had greater redox and buffering capacities and a larger portion of the fractions had high molecular mass. Also, the humification parameters (the CHAs/CFAs ratio and CHAs/Corg ratio) increased during the biodegradation. This is one of the few studies that describes the generation of humic substances during the biodegradation of oil compounds.
PB  - Elsevier
T2  - Science of the Total Environment
T1  - Study on the assessment of humification processes during biodegradation of heavy residual fuel oil
VL  - 797
SP  - 149099
DO  - 10.1016/j.scitotenv.2021.149099
ER  - 
@article{
author = "Avdalović, Jelena and Miletić, Srđan B. and Božović, Olga and Šolević-Knudsen, Tatjana and Stanković, Dalibor and Lugonja, Nikoleta and Spasić, Snežana and Joksimović, Kristina and Dragičević, Igor and Vrvić, Miroslav M.",
year = "2021",
abstract = "The aim of this study was to investigate the creation of humic substances during biodegradation of heavy residual fuel oil, because there are indications that substances similar to humic substances are generated during biodegradation of polycyclic aromatic hydrocarbons. In the study, which lasted for 110 days, biodegradation of heavy residual fuel oil was carried out in a layer of artificial soil substrate. The initial concentration of the total petroleum hydrocarbon in the prepared artificial soil substrate (biopile) was 23.1 g kg-1 dry weight (d.w.). At the end of the process, the total petroleum hydrocarbons were reduced to 8.1 g kg-1 d.w. in the inoculated biopile, while the content of humic acids increased during bioremediation from 3.15 g kg-1 d.w. to 4.95 g kg-1 d.w. The humic acids extracted from biopile during the biodegradation process were characterized by various chemical techniques (elemental analysis, spectrofluorimetric analysis, electrochemical measurements, and size exclusion chromatography). The results showed that levels of C, H and the H/C ratio decreased as the biodegradation process progressed. This indicated that humic acids aromatization process took place and this was confirmed by the spectrofluorimetric analysis. The increase of oxygen percentage and the O/C ratio in the humic acids after the biodegradation treatment indicated an increase in functional oxygen groups. Additional analyses of humic acids from the inoculated biopile showed that they were transformed during the bioremediation process. They had greater redox and buffering capacities and a larger portion of the fractions had high molecular mass. Also, the humification parameters (the CHAs/CFAs ratio and CHAs/Corg ratio) increased during the biodegradation. This is one of the few studies that describes the generation of humic substances during the biodegradation of oil compounds.",
publisher = "Elsevier",
journal = "Science of the Total Environment",
title = "Study on the assessment of humification processes during biodegradation of heavy residual fuel oil",
volume = "797",
pages = "149099",
doi = "10.1016/j.scitotenv.2021.149099"
}
Avdalović, J., Miletić, S. B., Božović, O., Šolević-Knudsen, T., Stanković, D., Lugonja, N., Spasić, S., Joksimović, K., Dragičević, I.,& Vrvić, M. M.. (2021). Study on the assessment of humification processes during biodegradation of heavy residual fuel oil. in Science of the Total Environment
Elsevier., 797, 149099.
https://doi.org/10.1016/j.scitotenv.2021.149099
Avdalović J, Miletić SB, Božović O, Šolević-Knudsen T, Stanković D, Lugonja N, Spasić S, Joksimović K, Dragičević I, Vrvić MM. Study on the assessment of humification processes during biodegradation of heavy residual fuel oil. in Science of the Total Environment. 2021;797:149099.
doi:10.1016/j.scitotenv.2021.149099 .
Avdalović, Jelena, Miletić, Srđan B., Božović, Olga, Šolević-Knudsen, Tatjana, Stanković, Dalibor, Lugonja, Nikoleta, Spasić, Snežana, Joksimović, Kristina, Dragičević, Igor, Vrvić, Miroslav M., "Study on the assessment of humification processes during biodegradation of heavy residual fuel oil" in Science of the Total Environment, 797 (2021):149099,
https://doi.org/10.1016/j.scitotenv.2021.149099 . .

Oxidized humic acids from the soil of heat power plant

Miletić, Srđan B.; Avdalović, Jelena; Milić, Jelena; Ilić, Mila; Žerađanin, Aleksandra; Joksimović, Kristina; Spasić, Snežana

(Serbia : Serbian Chemical Society, 2020)

TY  - JOUR
AU  - Miletić, Srđan B.
AU  - Avdalović, Jelena
AU  - Milić, Jelena
AU  - Ilić, Mila
AU  - Žerađanin, Aleksandra
AU  - Joksimović, Kristina
AU  - Spasić, Snežana
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4970
AB  - Humic acids isolated from the soil of a heat power plant (HA-E) contaminated with oil were analyzed by Fourier transform infrared spectroscopy (FTIR). In comparison with a humic acids standard (HA-S), a lack of an intense broad band of the stretching vibrations of hydrogen-bonded hydroxyl groups (3600–3200 cm-1) is evident. The HA-E spectra have a peak at 1649 cm-1, which could belong to carbonyl groups. HA-E are heavily oxidized and among the isolated microorganisms, Achromobacter denitrificans may be responsible for such intensive oxidation of HA-E. To the phylogenetically diverse nitrate-reducing microorganisms that have the capacity to utilize reduced HA as electron donors in soils, A. denitrificans can be added.
AB  - Хуминске киселине, изоловане из земљишта контаминираног нафтом из топлане (HA-E) је анализирано уз помоћ инфрацрвеног спектрометра (FTIR). У поређењу са стандардом хуминских киселина (HA-S) уочљив је недостатак интензивног пика вибрација водоничне везе из хидоксилне групе (3600–3200 cm-1). HA-E има пик на 1649 cm-1 који вероватно припада карбонилној групи. HA-E су веома оксидоване, а претпоставља се да су микроорганизми Achromobacter denitrificans за ову интензивну оксидацију HA-E. Они су филогенетски различити нитрат-редукујући микроорганизми који имају капацитет да редукују хуминске киселине где се понашају као електрон донори у земљишту.
PB  - Serbia : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Oxidized humic acids from the soil of heat power plant
T1  - Oksidovane huminske kiseline iz toplane
VL  - 85
IS  - 3
SP  - 421
EP  - 426
DO  - 10.2298/JSC190726099M
ER  - 
@article{
author = "Miletić, Srđan B. and Avdalović, Jelena and Milić, Jelena and Ilić, Mila and Žerađanin, Aleksandra and Joksimović, Kristina and Spasić, Snežana",
year = "2020",
abstract = "Humic acids isolated from the soil of a heat power plant (HA-E) contaminated with oil were analyzed by Fourier transform infrared spectroscopy (FTIR). In comparison with a humic acids standard (HA-S), a lack of an intense broad band of the stretching vibrations of hydrogen-bonded hydroxyl groups (3600–3200 cm-1) is evident. The HA-E spectra have a peak at 1649 cm-1, which could belong to carbonyl groups. HA-E are heavily oxidized and among the isolated microorganisms, Achromobacter denitrificans may be responsible for such intensive oxidation of HA-E. To the phylogenetically diverse nitrate-reducing microorganisms that have the capacity to utilize reduced HA as electron donors in soils, A. denitrificans can be added., Хуминске киселине, изоловане из земљишта контаминираног нафтом из топлане (HA-E) је анализирано уз помоћ инфрацрвеног спектрометра (FTIR). У поређењу са стандардом хуминских киселина (HA-S) уочљив је недостатак интензивног пика вибрација водоничне везе из хидоксилне групе (3600–3200 cm-1). HA-E има пик на 1649 cm-1 који вероватно припада карбонилној групи. HA-E су веома оксидоване, а претпоставља се да су микроорганизми Achromobacter denitrificans за ову интензивну оксидацију HA-E. Они су филогенетски различити нитрат-редукујући микроорганизми који имају капацитет да редукују хуминске киселине где се понашају као електрон донори у земљишту.",
publisher = "Serbia : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Oxidized humic acids from the soil of heat power plant, Oksidovane huminske kiseline iz toplane",
volume = "85",
number = "3",
pages = "421-426",
doi = "10.2298/JSC190726099M"
}
Miletić, S. B., Avdalović, J., Milić, J., Ilić, M., Žerađanin, A., Joksimović, K.,& Spasić, S.. (2020). Oxidized humic acids from the soil of heat power plant. in Journal of the Serbian Chemical Society
Serbia : Serbian Chemical Society., 85(3), 421-426.
https://doi.org/10.2298/JSC190726099M
Miletić SB, Avdalović J, Milić J, Ilić M, Žerađanin A, Joksimović K, Spasić S. Oxidized humic acids from the soil of heat power plant. in Journal of the Serbian Chemical Society. 2020;85(3):421-426.
doi:10.2298/JSC190726099M .
Miletić, Srđan B., Avdalović, Jelena, Milić, Jelena, Ilić, Mila, Žerađanin, Aleksandra, Joksimović, Kristina, Spasić, Snežana, "Oxidized humic acids from the soil of heat power plant" in Journal of the Serbian Chemical Society, 85, no. 3 (2020):421-426,
https://doi.org/10.2298/JSC190726099M . .

Supplementary data for article: Dimitrijević, M. S.; Bogdanović Pristov, J.; Žižić, M.; Stanković, D. M.; Bajuk-Bogdanović, D.; Stanić, M.; Spasić, S.; Hagen, W.; Spasojević, I. Biliverdin-Copper Complex at Physiological PH. Dalton Transactions 2019, 48 (18), 6061–6070. https://doi.org/10.1039/c8dt04724c

Dimitrijević, Milena S.; Bogdanović Pristov, Jelena; Žižić, Milan; Stanković, Dalibor; Bajuk-Bogdanović, Danica; Stanić, Marina; Spasić, Snežana; Hagen, Wilfred; Spasojević, Ivan

(2019)

TY  - DATA
AU  - Dimitrijević, Milena S.
AU  - Bogdanović Pristov, Jelena
AU  - Žižić, Milan
AU  - Stanković, Dalibor
AU  - Bajuk-Bogdanović, Danica
AU  - Stanić, Marina
AU  - Spasić, Snežana
AU  - Hagen, Wilfred
AU  - Spasojević, Ivan
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3069
T2  - Dalton Transactions
T1  - Supplementary data for article:
Dimitrijević, M. S.; Bogdanović Pristov, J.; Žižić, M.; Stanković, D. M.; Bajuk-Bogdanović, D.; Stanić, M.; Spasić, S.; Hagen, W.; Spasojević, I. Biliverdin-Copper Complex at Physiological PH. Dalton Transactions 2019, 48 (18), 6061–6070. https://doi.org/10.1039/c8dt04724c
VL  - 48
IS  - 18
SP  - 6061
EP  - 6070
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3069
ER  - 
@misc{
author = "Dimitrijević, Milena S. and Bogdanović Pristov, Jelena and Žižić, Milan and Stanković, Dalibor and Bajuk-Bogdanović, Danica and Stanić, Marina and Spasić, Snežana and Hagen, Wilfred and Spasojević, Ivan",
year = "2019",
journal = "Dalton Transactions",
title = "Supplementary data for article:
Dimitrijević, M. S.; Bogdanović Pristov, J.; Žižić, M.; Stanković, D. M.; Bajuk-Bogdanović, D.; Stanić, M.; Spasić, S.; Hagen, W.; Spasojević, I. Biliverdin-Copper Complex at Physiological PH. Dalton Transactions 2019, 48 (18), 6061–6070. https://doi.org/10.1039/c8dt04724c",
volume = "48",
number = "18",
pages = "6061-6070",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3069"
}
Dimitrijević, M. S., Bogdanović Pristov, J., Žižić, M., Stanković, D., Bajuk-Bogdanović, D., Stanić, M., Spasić, S., Hagen, W.,& Spasojević, I.. (2019). Supplementary data for article:
Dimitrijević, M. S.; Bogdanović Pristov, J.; Žižić, M.; Stanković, D. M.; Bajuk-Bogdanović, D.; Stanić, M.; Spasić, S.; Hagen, W.; Spasojević, I. Biliverdin-Copper Complex at Physiological PH. Dalton Transactions 2019, 48 (18), 6061–6070. https://doi.org/10.1039/c8dt04724c. in Dalton Transactions, 48(18), 6061-6070.
https://hdl.handle.net/21.15107/rcub_cherry_3069
Dimitrijević MS, Bogdanović Pristov J, Žižić M, Stanković D, Bajuk-Bogdanović D, Stanić M, Spasić S, Hagen W, Spasojević I. Supplementary data for article:
Dimitrijević, M. S.; Bogdanović Pristov, J.; Žižić, M.; Stanković, D. M.; Bajuk-Bogdanović, D.; Stanić, M.; Spasić, S.; Hagen, W.; Spasojević, I. Biliverdin-Copper Complex at Physiological PH. Dalton Transactions 2019, 48 (18), 6061–6070. https://doi.org/10.1039/c8dt04724c. in Dalton Transactions. 2019;48(18):6061-6070.
https://hdl.handle.net/21.15107/rcub_cherry_3069 .
Dimitrijević, Milena S., Bogdanović Pristov, Jelena, Žižić, Milan, Stanković, Dalibor, Bajuk-Bogdanović, Danica, Stanić, Marina, Spasić, Snežana, Hagen, Wilfred, Spasojević, Ivan, "Supplementary data for article:
Dimitrijević, M. S.; Bogdanović Pristov, J.; Žižić, M.; Stanković, D. M.; Bajuk-Bogdanović, D.; Stanić, M.; Spasić, S.; Hagen, W.; Spasojević, I. Biliverdin-Copper Complex at Physiological PH. Dalton Transactions 2019, 48 (18), 6061–6070. https://doi.org/10.1039/c8dt04724c" in Dalton Transactions, 48, no. 18 (2019):6061-6070,
https://hdl.handle.net/21.15107/rcub_cherry_3069 .

Biliverdin-copper complex at physiological pH

Dimitrijević, Milena S.; Bogdanović Pristov, Jelena; Žižić, Milan; Stanković, Dalibor; Bajuk-Bogdanović, Danica; Stanić, Marina; Spasić, Snežana; Hagen, Wilfred; Spasojević, Ivan

(2019)

TY  - JOUR
AU  - Dimitrijević, Milena S.
AU  - Bogdanović Pristov, Jelena
AU  - Žižić, Milan
AU  - Stanković, Dalibor
AU  - Bajuk-Bogdanović, Danica
AU  - Stanić, Marina
AU  - Spasić, Snežana
AU  - Hagen, Wilfred
AU  - Spasojević, Ivan
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3068
AB  - Biliverdin (BV), a product of heme catabolism, is known to interact with transition metals, but the details of such interactions under physiological conditions are scarce. Herein, we examined coordinate/redox interactions of BV with Cu2+ in phosphate buffer at pH 7.4, using spectrophotometry, HESI-MS, Raman spectroscopy, 1 H NMR, EPR, fluorimetry, and electrochemical methods. BV formed a stable coordination complex with copper in 1 : 1 stoichiometry. The structure of BV was more planar and energetically stable in the complex. The complex showed strong paramagnetic effects that were attributed to an unpaired delocalized e−. The delocalized electron may come from BV or Cu2+, so the complex is formally composed either of BV radical cation and Cu1+ or of BV radical anion and Cu3+. The complex underwent oxidation only in the presence of both O2 and an excess of Cu2+, or a strong oxidizing agent, and it was resistant to reducing agents. The biological effects of the stable BV metallocomplex containing a delocalized unpaired electron should be further examined, and may provide an answer to the long-standing question of high energy investment in the catabolism of BV, which represents a relatively harmless molecule per se.
T2  - Dalton Transactions
T1  - Biliverdin-copper complex at physiological pH
VL  - 48
IS  - 18
SP  - 6061
EP  - 6070
DO  - 10.1039/c8dt04724c
ER  - 
@article{
author = "Dimitrijević, Milena S. and Bogdanović Pristov, Jelena and Žižić, Milan and Stanković, Dalibor and Bajuk-Bogdanović, Danica and Stanić, Marina and Spasić, Snežana and Hagen, Wilfred and Spasojević, Ivan",
year = "2019",
abstract = "Biliverdin (BV), a product of heme catabolism, is known to interact with transition metals, but the details of such interactions under physiological conditions are scarce. Herein, we examined coordinate/redox interactions of BV with Cu2+ in phosphate buffer at pH 7.4, using spectrophotometry, HESI-MS, Raman spectroscopy, 1 H NMR, EPR, fluorimetry, and electrochemical methods. BV formed a stable coordination complex with copper in 1 : 1 stoichiometry. The structure of BV was more planar and energetically stable in the complex. The complex showed strong paramagnetic effects that were attributed to an unpaired delocalized e−. The delocalized electron may come from BV or Cu2+, so the complex is formally composed either of BV radical cation and Cu1+ or of BV radical anion and Cu3+. The complex underwent oxidation only in the presence of both O2 and an excess of Cu2+, or a strong oxidizing agent, and it was resistant to reducing agents. The biological effects of the stable BV metallocomplex containing a delocalized unpaired electron should be further examined, and may provide an answer to the long-standing question of high energy investment in the catabolism of BV, which represents a relatively harmless molecule per se.",
journal = "Dalton Transactions",
title = "Biliverdin-copper complex at physiological pH",
volume = "48",
number = "18",
pages = "6061-6070",
doi = "10.1039/c8dt04724c"
}
Dimitrijević, M. S., Bogdanović Pristov, J., Žižić, M., Stanković, D., Bajuk-Bogdanović, D., Stanić, M., Spasić, S., Hagen, W.,& Spasojević, I.. (2019). Biliverdin-copper complex at physiological pH. in Dalton Transactions, 48(18), 6061-6070.
https://doi.org/10.1039/c8dt04724c
Dimitrijević MS, Bogdanović Pristov J, Žižić M, Stanković D, Bajuk-Bogdanović D, Stanić M, Spasić S, Hagen W, Spasojević I. Biliverdin-copper complex at physiological pH. in Dalton Transactions. 2019;48(18):6061-6070.
doi:10.1039/c8dt04724c .
Dimitrijević, Milena S., Bogdanović Pristov, Jelena, Žižić, Milan, Stanković, Dalibor, Bajuk-Bogdanović, Danica, Stanić, Marina, Spasić, Snežana, Hagen, Wilfred, Spasojević, Ivan, "Biliverdin-copper complex at physiological pH" in Dalton Transactions, 48, no. 18 (2019):6061-6070,
https://doi.org/10.1039/c8dt04724c . .
8
6
7

Biliverdin-copper complex at physiological pH

Dimitrijević, Milena S.; Bogdanović Pristov, Jelena; Žižić, Milan; Stanković, Dalibor; Bajuk-Bogdanović, Danica; Stanić, Marina; Spasić, Snežana; Hagen, Wilfred; Spasojević, Ivan

(2019)

TY  - JOUR
AU  - Dimitrijević, Milena S.
AU  - Bogdanović Pristov, Jelena
AU  - Žižić, Milan
AU  - Stanković, Dalibor
AU  - Bajuk-Bogdanović, Danica
AU  - Stanić, Marina
AU  - Spasić, Snežana
AU  - Hagen, Wilfred
AU  - Spasojević, Ivan
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3066
AB  - Biliverdin (BV), a product of heme catabolism, is known to interact with transition metals, but the details of such interactions under physiological conditions are scarce. Herein, we examined coordinate/redox interactions of BV with Cu2+ in phosphate buffer at pH 7.4, using spectrophotometry, HESI-MS, Raman spectroscopy, 1 H NMR, EPR, fluorimetry, and electrochemical methods. BV formed a stable coordination complex with copper in 1 : 1 stoichiometry. The structure of BV was more planar and energetically stable in the complex. The complex showed strong paramagnetic effects that were attributed to an unpaired delocalized e−. The delocalized electron may come from BV or Cu2+, so the complex is formally composed either of BV radical cation and Cu1+ or of BV radical anion and Cu3+. The complex underwent oxidation only in the presence of both O2 and an excess of Cu2+, or a strong oxidizing agent, and it was resistant to reducing agents. The biological effects of the stable BV metallocomplex containing a delocalized unpaired electron should be further examined, and may provide an answer to the long-standing question of high energy investment in the catabolism of BV, which represents a relatively harmless molecule per se.
T2  - Dalton Transactions
T1  - Biliverdin-copper complex at physiological pH
VL  - 48
IS  - 18
SP  - 6061
EP  - 6070
DO  - 10.1039/c8dt04724c
ER  - 
@article{
author = "Dimitrijević, Milena S. and Bogdanović Pristov, Jelena and Žižić, Milan and Stanković, Dalibor and Bajuk-Bogdanović, Danica and Stanić, Marina and Spasić, Snežana and Hagen, Wilfred and Spasojević, Ivan",
year = "2019",
abstract = "Biliverdin (BV), a product of heme catabolism, is known to interact with transition metals, but the details of such interactions under physiological conditions are scarce. Herein, we examined coordinate/redox interactions of BV with Cu2+ in phosphate buffer at pH 7.4, using spectrophotometry, HESI-MS, Raman spectroscopy, 1 H NMR, EPR, fluorimetry, and electrochemical methods. BV formed a stable coordination complex with copper in 1 : 1 stoichiometry. The structure of BV was more planar and energetically stable in the complex. The complex showed strong paramagnetic effects that were attributed to an unpaired delocalized e−. The delocalized electron may come from BV or Cu2+, so the complex is formally composed either of BV radical cation and Cu1+ or of BV radical anion and Cu3+. The complex underwent oxidation only in the presence of both O2 and an excess of Cu2+, or a strong oxidizing agent, and it was resistant to reducing agents. The biological effects of the stable BV metallocomplex containing a delocalized unpaired electron should be further examined, and may provide an answer to the long-standing question of high energy investment in the catabolism of BV, which represents a relatively harmless molecule per se.",
journal = "Dalton Transactions",
title = "Biliverdin-copper complex at physiological pH",
volume = "48",
number = "18",
pages = "6061-6070",
doi = "10.1039/c8dt04724c"
}
Dimitrijević, M. S., Bogdanović Pristov, J., Žižić, M., Stanković, D., Bajuk-Bogdanović, D., Stanić, M., Spasić, S., Hagen, W.,& Spasojević, I.. (2019). Biliverdin-copper complex at physiological pH. in Dalton Transactions, 48(18), 6061-6070.
https://doi.org/10.1039/c8dt04724c
Dimitrijević MS, Bogdanović Pristov J, Žižić M, Stanković D, Bajuk-Bogdanović D, Stanić M, Spasić S, Hagen W, Spasojević I. Biliverdin-copper complex at physiological pH. in Dalton Transactions. 2019;48(18):6061-6070.
doi:10.1039/c8dt04724c .
Dimitrijević, Milena S., Bogdanović Pristov, Jelena, Žižić, Milan, Stanković, Dalibor, Bajuk-Bogdanović, Danica, Stanić, Marina, Spasić, Snežana, Hagen, Wilfred, Spasojević, Ivan, "Biliverdin-copper complex at physiological pH" in Dalton Transactions, 48, no. 18 (2019):6061-6070,
https://doi.org/10.1039/c8dt04724c . .
8
6
7

Opposite clozapine and ziprasidone effects on the reactivity of plasma albumin SH-group are the consequence of their different binding properties dependent on protein fatty acids content

Uzelac, Tamara N.; Nikolić-Kokić, Aleksandra; Spasić, Snežana; Mačvanin, Mirjana T.; Nikolić, Milan; Mandić, Ljuba M.; Jovanović, Vesna B.

(2019)

TY  - JOUR
AU  - Uzelac, Tamara N.
AU  - Nikolić-Kokić, Aleksandra
AU  - Spasić, Snežana
AU  - Mačvanin, Mirjana T.
AU  - Nikolić, Milan
AU  - Mandić, Ljuba M.
AU  - Jovanović, Vesna B.
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3333
AB  - Antipsychotic drugs interfere with the antioxidant defense system provoking complex and often toxicological effects. Here we examined differences in plasma albumin reduced free thiol (SH) group content and its reactivity as a consequence of clozapine (CLZ) and ziprasidone (ZIP) binding. Chronic administration of CLZ reduced, whereas treatment with ZIP increased albumin-SH content in rats. Regardless of the ratio of stearic acid (SA) bound to protein, in vitro binding of ZIP to human serum albumin (HSA) increased both the SH group level and reactivity. In contrast, the effect of CLZ on HSA-SH reactivity was dependent on HSA to SA molar ratio. CLZ binding was accompanied by an increase in HSA-SH reactivity in samples with normal, but a reduction of its reactivity level with higher SA/HSA ratio, compared to drug-free samples. We demonstrate by steady-state fluorescence quenching studies that an increase in SA binding to HSA is associated with a significant reduction of binding constant for both antipsychotics. In addition, this is the first report of quantitative characterization of ZIP binding to HSA. Our findings suggest that albumin-SH content and reactivity is modulated by ZIP towards an increased antioxidant defense capacity in circulation, as opposed to CLZ, which can contribute to the safer, more effective treatment of schizophrenia.
T2  - Chemico-Biological Interactions
T1  - Opposite clozapine and ziprasidone effects on the reactivity of plasma albumin SH-group are the consequence of their different binding properties dependent on protein fatty acids content
VL  - 311
SP  - 1
EP  - 7
DO  - 10.1016/j.cbi.2019.108787
ER  - 
@article{
author = "Uzelac, Tamara N. and Nikolić-Kokić, Aleksandra and Spasić, Snežana and Mačvanin, Mirjana T. and Nikolić, Milan and Mandić, Ljuba M. and Jovanović, Vesna B.",
year = "2019",
abstract = "Antipsychotic drugs interfere with the antioxidant defense system provoking complex and often toxicological effects. Here we examined differences in plasma albumin reduced free thiol (SH) group content and its reactivity as a consequence of clozapine (CLZ) and ziprasidone (ZIP) binding. Chronic administration of CLZ reduced, whereas treatment with ZIP increased albumin-SH content in rats. Regardless of the ratio of stearic acid (SA) bound to protein, in vitro binding of ZIP to human serum albumin (HSA) increased both the SH group level and reactivity. In contrast, the effect of CLZ on HSA-SH reactivity was dependent on HSA to SA molar ratio. CLZ binding was accompanied by an increase in HSA-SH reactivity in samples with normal, but a reduction of its reactivity level with higher SA/HSA ratio, compared to drug-free samples. We demonstrate by steady-state fluorescence quenching studies that an increase in SA binding to HSA is associated with a significant reduction of binding constant for both antipsychotics. In addition, this is the first report of quantitative characterization of ZIP binding to HSA. Our findings suggest that albumin-SH content and reactivity is modulated by ZIP towards an increased antioxidant defense capacity in circulation, as opposed to CLZ, which can contribute to the safer, more effective treatment of schizophrenia.",
journal = "Chemico-Biological Interactions",
title = "Opposite clozapine and ziprasidone effects on the reactivity of plasma albumin SH-group are the consequence of their different binding properties dependent on protein fatty acids content",
volume = "311",
pages = "1-7",
doi = "10.1016/j.cbi.2019.108787"
}
Uzelac, T. N., Nikolić-Kokić, A., Spasić, S., Mačvanin, M. T., Nikolić, M., Mandić, L. M.,& Jovanović, V. B.. (2019). Opposite clozapine and ziprasidone effects on the reactivity of plasma albumin SH-group are the consequence of their different binding properties dependent on protein fatty acids content. in Chemico-Biological Interactions, 311, 1-7.
https://doi.org/10.1016/j.cbi.2019.108787
Uzelac TN, Nikolić-Kokić A, Spasić S, Mačvanin MT, Nikolić M, Mandić LM, Jovanović VB. Opposite clozapine and ziprasidone effects on the reactivity of plasma albumin SH-group are the consequence of their different binding properties dependent on protein fatty acids content. in Chemico-Biological Interactions. 2019;311:1-7.
doi:10.1016/j.cbi.2019.108787 .
Uzelac, Tamara N., Nikolić-Kokić, Aleksandra, Spasić, Snežana, Mačvanin, Mirjana T., Nikolić, Milan, Mandić, Ljuba M., Jovanović, Vesna B., "Opposite clozapine and ziprasidone effects on the reactivity of plasma albumin SH-group are the consequence of their different binding properties dependent on protein fatty acids content" in Chemico-Biological Interactions, 311 (2019):1-7,
https://doi.org/10.1016/j.cbi.2019.108787 . .
1
1

Supplementary data for the article: Uzelac, T. N.; Nikolić-Kokić, A. L.; Spasić, S. D.; Mačvanin, M. T.; Nikolić, M. R.; Mandić, L. M.; Jovanović, V. B. Opposite Clozapine and Ziprasidone Effects on the Reactivity of Plasma Albumin SH-Group Are the Consequence of Their Different Binding Properties Dependent on Protein Fatty Acids Content. Chemico-Biological Interactions 2019, 311. https://doi.org/10.1016/j.cbi.2019.108787

Uzelac, Tamara N.; Nikolić-Kokić, Aleksandra; Spasić, Snežana; Mačvanin, Mirjana T.; Nikolić, Milan; Mandić, Ljuba M.; Jovanović, Vesna B.

(2019)

TY  - DATA
AU  - Uzelac, Tamara N.
AU  - Nikolić-Kokić, Aleksandra
AU  - Spasić, Snežana
AU  - Mačvanin, Mirjana T.
AU  - Nikolić, Milan
AU  - Mandić, Ljuba M.
AU  - Jovanović, Vesna B.
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3335
T2  - Chemico-Biological Interactions
T1  - Supplementary data for the article: Uzelac, T. N.; Nikolić-Kokić, A. L.; Spasić, S. D.; Mačvanin, M. T.; Nikolić, M. R.; Mandić, L. M.; Jovanović, V. B. Opposite Clozapine and Ziprasidone Effects on the Reactivity of Plasma Albumin SH-Group Are the Consequence of Their Different Binding Properties Dependent on Protein Fatty Acids Content. Chemico-Biological Interactions 2019, 311. https://doi.org/10.1016/j.cbi.2019.108787
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3335
ER  - 
@misc{
author = "Uzelac, Tamara N. and Nikolić-Kokić, Aleksandra and Spasić, Snežana and Mačvanin, Mirjana T. and Nikolić, Milan and Mandić, Ljuba M. and Jovanović, Vesna B.",
year = "2019",
journal = "Chemico-Biological Interactions",
title = "Supplementary data for the article: Uzelac, T. N.; Nikolić-Kokić, A. L.; Spasić, S. D.; Mačvanin, M. T.; Nikolić, M. R.; Mandić, L. M.; Jovanović, V. B. Opposite Clozapine and Ziprasidone Effects on the Reactivity of Plasma Albumin SH-Group Are the Consequence of Their Different Binding Properties Dependent on Protein Fatty Acids Content. Chemico-Biological Interactions 2019, 311. https://doi.org/10.1016/j.cbi.2019.108787",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3335"
}
Uzelac, T. N., Nikolić-Kokić, A., Spasić, S., Mačvanin, M. T., Nikolić, M., Mandić, L. M.,& Jovanović, V. B.. (2019). Supplementary data for the article: Uzelac, T. N.; Nikolić-Kokić, A. L.; Spasić, S. D.; Mačvanin, M. T.; Nikolić, M. R.; Mandić, L. M.; Jovanović, V. B. Opposite Clozapine and Ziprasidone Effects on the Reactivity of Plasma Albumin SH-Group Are the Consequence of Their Different Binding Properties Dependent on Protein Fatty Acids Content. Chemico-Biological Interactions 2019, 311. https://doi.org/10.1016/j.cbi.2019.108787. in Chemico-Biological Interactions.
https://hdl.handle.net/21.15107/rcub_cherry_3335
Uzelac TN, Nikolić-Kokić A, Spasić S, Mačvanin MT, Nikolić M, Mandić LM, Jovanović VB. Supplementary data for the article: Uzelac, T. N.; Nikolić-Kokić, A. L.; Spasić, S. D.; Mačvanin, M. T.; Nikolić, M. R.; Mandić, L. M.; Jovanović, V. B. Opposite Clozapine and Ziprasidone Effects on the Reactivity of Plasma Albumin SH-Group Are the Consequence of Their Different Binding Properties Dependent on Protein Fatty Acids Content. Chemico-Biological Interactions 2019, 311. https://doi.org/10.1016/j.cbi.2019.108787. in Chemico-Biological Interactions. 2019;.
https://hdl.handle.net/21.15107/rcub_cherry_3335 .
Uzelac, Tamara N., Nikolić-Kokić, Aleksandra, Spasić, Snežana, Mačvanin, Mirjana T., Nikolić, Milan, Mandić, Ljuba M., Jovanović, Vesna B., "Supplementary data for the article: Uzelac, T. N.; Nikolić-Kokić, A. L.; Spasić, S. D.; Mačvanin, M. T.; Nikolić, M. R.; Mandić, L. M.; Jovanović, V. B. Opposite Clozapine and Ziprasidone Effects on the Reactivity of Plasma Albumin SH-Group Are the Consequence of Their Different Binding Properties Dependent on Protein Fatty Acids Content. Chemico-Biological Interactions 2019, 311. https://doi.org/10.1016/j.cbi.2019.108787" in Chemico-Biological Interactions (2019),
https://hdl.handle.net/21.15107/rcub_cherry_3335 .

Opposite clozapine and ziprasidone effects on the reactivity of plasma albumin SH-group are the consequence of their different binding properties dependent on protein fatty acids content

Uzelac, Tamara N.; Nikolić-Kokić, Aleksandra; Spasić, Snežana; Mačvanin, Mirjana T.; Nikolić, Milan; Mandić, Ljuba M.; Jovanović, Vesna B.

(Elsevier, 2019)

TY  - JOUR
AU  - Uzelac, Tamara N.
AU  - Nikolić-Kokić, Aleksandra
AU  - Spasić, Snežana
AU  - Mačvanin, Mirjana T.
AU  - Nikolić, Milan
AU  - Mandić, Ljuba M.
AU  - Jovanović, Vesna B.
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3865
AB  - Antipsychotic drugs interfere with the antioxidant defense system provoking complex and often toxicological effects. Here we examined differences in plasma albumin reduced free thiol (SH) group content and its reactivity as a consequence of clozapine (CLZ) and ziprasidone (ZIP) binding. Chronic administration of CLZ reduced, whereas treatment with ZIP increased albumin-SH content in rats. Regardless of the ratio of stearic acid (SA) bound to protein, in vitro binding of ZIP to human serum albumin (HSA) increased both the SH group level and reactivity. In contrast, the effect of CLZ on HSA-SH reactivity was dependent on HSA to SA molar ratio. CLZ binding was accompanied by an increase in HSA-SH reactivity in samples with normal, but a reduction of its reactivity level with higher SA/HSA ratio, compared to drug-free samples. We demonstrate by steady-state fluorescence quenching studies that an increase in SA binding to HSA is associated with a significant reduction of binding constant for both antipsychotics. In addition, this is the first report of quantitative characterization of ZIP binding to HSA. Our findings suggest that albumin-SH content and reactivity is modulated by ZIP towards an increased antioxidant defense capacity in circulation, as opposed to CLZ, which can contribute to the safer, more effective treatment of schizophrenia.
PB  - Elsevier
T2  - Chemico-Biological Interactions
T1  - Opposite clozapine and ziprasidone effects on the reactivity of plasma albumin SH-group are the consequence of their different binding properties dependent on protein fatty acids content
VL  - 311
IS  - 108787
DO  - 10.1016/j.cbi.2019.108787
ER  - 
@article{
author = "Uzelac, Tamara N. and Nikolić-Kokić, Aleksandra and Spasić, Snežana and Mačvanin, Mirjana T. and Nikolić, Milan and Mandić, Ljuba M. and Jovanović, Vesna B.",
year = "2019",
abstract = "Antipsychotic drugs interfere with the antioxidant defense system provoking complex and often toxicological effects. Here we examined differences in plasma albumin reduced free thiol (SH) group content and its reactivity as a consequence of clozapine (CLZ) and ziprasidone (ZIP) binding. Chronic administration of CLZ reduced, whereas treatment with ZIP increased albumin-SH content in rats. Regardless of the ratio of stearic acid (SA) bound to protein, in vitro binding of ZIP to human serum albumin (HSA) increased both the SH group level and reactivity. In contrast, the effect of CLZ on HSA-SH reactivity was dependent on HSA to SA molar ratio. CLZ binding was accompanied by an increase in HSA-SH reactivity in samples with normal, but a reduction of its reactivity level with higher SA/HSA ratio, compared to drug-free samples. We demonstrate by steady-state fluorescence quenching studies that an increase in SA binding to HSA is associated with a significant reduction of binding constant for both antipsychotics. In addition, this is the first report of quantitative characterization of ZIP binding to HSA. Our findings suggest that albumin-SH content and reactivity is modulated by ZIP towards an increased antioxidant defense capacity in circulation, as opposed to CLZ, which can contribute to the safer, more effective treatment of schizophrenia.",
publisher = "Elsevier",
journal = "Chemico-Biological Interactions",
title = "Opposite clozapine and ziprasidone effects on the reactivity of plasma albumin SH-group are the consequence of their different binding properties dependent on protein fatty acids content",
volume = "311",
number = "108787",
doi = "10.1016/j.cbi.2019.108787"
}
Uzelac, T. N., Nikolić-Kokić, A., Spasić, S., Mačvanin, M. T., Nikolić, M., Mandić, L. M.,& Jovanović, V. B.. (2019). Opposite clozapine and ziprasidone effects on the reactivity of plasma albumin SH-group are the consequence of their different binding properties dependent on protein fatty acids content. in Chemico-Biological Interactions
Elsevier., 311(108787).
https://doi.org/10.1016/j.cbi.2019.108787
Uzelac TN, Nikolić-Kokić A, Spasić S, Mačvanin MT, Nikolić M, Mandić LM, Jovanović VB. Opposite clozapine and ziprasidone effects on the reactivity of plasma albumin SH-group are the consequence of their different binding properties dependent on protein fatty acids content. in Chemico-Biological Interactions. 2019;311(108787).
doi:10.1016/j.cbi.2019.108787 .
Uzelac, Tamara N., Nikolić-Kokić, Aleksandra, Spasić, Snežana, Mačvanin, Mirjana T., Nikolić, Milan, Mandić, Ljuba M., Jovanović, Vesna B., "Opposite clozapine and ziprasidone effects on the reactivity of plasma albumin SH-group are the consequence of their different binding properties dependent on protein fatty acids content" in Chemico-Biological Interactions, 311, no. 108787 (2019),
https://doi.org/10.1016/j.cbi.2019.108787 . .
1

Redox properties of transitional milk from mothers of preterm infants

Minić, Simeon L.; Ješić, Miloš; Đurović, Dijana; Miletić, Srđan B.; Lugonja, Nikoleta; Marinković, Vesna; Nikolić-Kokić, Aleksandra; Spasić, Snežana; Vrvić, Miroslav M.

(Wiley, Hoboken, 2018)

TY  - JOUR
AU  - Minić, Simeon L.
AU  - Ješić, Miloš
AU  - Đurović, Dijana
AU  - Miletić, Srđan B.
AU  - Lugonja, Nikoleta
AU  - Marinković, Vesna
AU  - Nikolić-Kokić, Aleksandra
AU  - Spasić, Snežana
AU  - Vrvić, Miroslav M.
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2084
AB  - AimThere is a discrepancy between the amount of transitional milk produced by mothers of preterm infants and the low capacity of premature infants to consume it. This milk can be used in milk banks, but previous studies found that there are large variations in the level of host-defence proteins in individual samples of milk from mothers of premature infants, which implies that large individual variations in antioxidative defence composition are also possible. MethodsMilk samples were collected from 20 healthy mothers of preterm infants. We determined the values for non-enzymatic antioxidative capacity parameters (oxygen radical absorbance capacity (ORAC)), static oxidation-reduction potential (ORP), activities of antioxidant defence enzymes and the amount of vitamin C in whole milk, skim and whey fractions of transitional milk. ResultsThe main low-molecular-weight antioxidant in transitional milk is vitamin C and most of it is contained in whey. ORAC is higher in whole transitional milk than in skim milk and whey, and ORP is lower in whole transitional milk than that in skim milk and whey. Antioxidative enzyme activities are similar in all individual samples of transitional milk from mothers of preterm infants. ConclusionsOur results indicate that transitional milk of mothers of preterm infants shows slow individual variations in antioxidative defence composition; therefore, it can be used in human milk banks.
PB  - Wiley, Hoboken
T2  - Journal of Paediatrics and Child Health
T1  - Redox properties of transitional milk from mothers of preterm infants
VL  - 54
IS  - 2
SP  - 160
EP  - 164
DO  - 10.1111/jpc.13676
UR  - Kon_3415
ER  - 
@article{
author = "Minić, Simeon L. and Ješić, Miloš and Đurović, Dijana and Miletić, Srđan B. and Lugonja, Nikoleta and Marinković, Vesna and Nikolić-Kokić, Aleksandra and Spasić, Snežana and Vrvić, Miroslav M.",
year = "2018",
abstract = "AimThere is a discrepancy between the amount of transitional milk produced by mothers of preterm infants and the low capacity of premature infants to consume it. This milk can be used in milk banks, but previous studies found that there are large variations in the level of host-defence proteins in individual samples of milk from mothers of premature infants, which implies that large individual variations in antioxidative defence composition are also possible. MethodsMilk samples were collected from 20 healthy mothers of preterm infants. We determined the values for non-enzymatic antioxidative capacity parameters (oxygen radical absorbance capacity (ORAC)), static oxidation-reduction potential (ORP), activities of antioxidant defence enzymes and the amount of vitamin C in whole milk, skim and whey fractions of transitional milk. ResultsThe main low-molecular-weight antioxidant in transitional milk is vitamin C and most of it is contained in whey. ORAC is higher in whole transitional milk than in skim milk and whey, and ORP is lower in whole transitional milk than that in skim milk and whey. Antioxidative enzyme activities are similar in all individual samples of transitional milk from mothers of preterm infants. ConclusionsOur results indicate that transitional milk of mothers of preterm infants shows slow individual variations in antioxidative defence composition; therefore, it can be used in human milk banks.",
publisher = "Wiley, Hoboken",
journal = "Journal of Paediatrics and Child Health",
title = "Redox properties of transitional milk from mothers of preterm infants",
volume = "54",
number = "2",
pages = "160-164",
doi = "10.1111/jpc.13676",
url = "Kon_3415"
}
Minić, S. L., Ješić, M., Đurović, D., Miletić, S. B., Lugonja, N., Marinković, V., Nikolić-Kokić, A., Spasić, S.,& Vrvić, M. M.. (2018). Redox properties of transitional milk from mothers of preterm infants. in Journal of Paediatrics and Child Health
Wiley, Hoboken., 54(2), 160-164.
https://doi.org/10.1111/jpc.13676
Kon_3415
Minić SL, Ješić M, Đurović D, Miletić SB, Lugonja N, Marinković V, Nikolić-Kokić A, Spasić S, Vrvić MM. Redox properties of transitional milk from mothers of preterm infants. in Journal of Paediatrics and Child Health. 2018;54(2):160-164.
doi:10.1111/jpc.13676
Kon_3415 .
Minić, Simeon L., Ješić, Miloš, Đurović, Dijana, Miletić, Srđan B., Lugonja, Nikoleta, Marinković, Vesna, Nikolić-Kokić, Aleksandra, Spasić, Snežana, Vrvić, Miroslav M., "Redox properties of transitional milk from mothers of preterm infants" in Journal of Paediatrics and Child Health, 54, no. 2 (2018):160-164,
https://doi.org/10.1111/jpc.13676 .,
Kon_3415 .
4
2
2
3

Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity

Božić, Bojana; Korać, Jelena; Stanković, Dalibor; Stanić, Marina; Romanović, Mima; Pristov-Bogdanović, Jelena; Spasić, Snežana; Popović-Bijelić, Ana; Spasojević, Ivan; Bajčetić, Milica

(Elsevier, 2018)

TY  - JOUR
AU  - Božić, Bojana
AU  - Korać, Jelena
AU  - Stanković, Dalibor
AU  - Stanić, Marina
AU  - Romanović, Mima
AU  - Pristov-Bogdanović, Jelena
AU  - Spasić, Snežana
AU  - Popović-Bijelić, Ana
AU  - Spasojević, Ivan
AU  - Bajčetić, Milica
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2940
AB  - An increase in the copper pool in body fluids has been related to a number of pathological conditions, including infections. Copper ions may affect antibiotics via the formation of coordination bonds and/or redox reactions. Herein, we analyzed the interactions of Cu2+ with eight β-lactam antibiotics using UV–Vis spectrophotometry, EPR spectroscopy, and electrochemical methods. Penicillin G did not show any detectable interactions with Cu2+. Ampicillin, amoxicillin and cephalexin formed stable colored complexes with octahedral coordination environment of Cu2+ with tetragonal distortion, and primary amine group as the site of coordinate bond formation. These β-lactams increased the solubility of Cu2+ in the phosphate buffer. Ceftazidime and Cu2+ formed a complex with a similar geometry and gave rise to an organic radical. Ceftriaxone-Cu2+ complex appears to exhibit different geometry. All complexes showed 1:1 stoichiometry. Cefaclor reduced Cu2+ to Cu1+ that further reacted with molecular oxygen to produce hydrogen peroxide. Finally, meropenem underwent degradation in the presence of copper. The analysis of activity against Escherichia coli and Staphylococcus aureus showed that the effects of meropenem, amoxicillin, ampicillin, and ceftriaxone were significantly hindered in the presence of copper ions. The interactions with copper ions should be taken into account regarding the problem of antibiotic resistance and in the selection of the most efficient antimicrobial therapy for patients with altered copper homeostasis. © 2018 Elsevier Inc.
PB  - Elsevier
T2  - Free Radical Biology and Medicine
T1  - Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity
VL  - 129
SP  - 279
EP  - 285
DO  - 10.1016/j.freeradbiomed.2018.09.038
UR  - Kon_1320
ER  - 
@article{
author = "Božić, Bojana and Korać, Jelena and Stanković, Dalibor and Stanić, Marina and Romanović, Mima and Pristov-Bogdanović, Jelena and Spasić, Snežana and Popović-Bijelić, Ana and Spasojević, Ivan and Bajčetić, Milica",
year = "2018",
abstract = "An increase in the copper pool in body fluids has been related to a number of pathological conditions, including infections. Copper ions may affect antibiotics via the formation of coordination bonds and/or redox reactions. Herein, we analyzed the interactions of Cu2+ with eight β-lactam antibiotics using UV–Vis spectrophotometry, EPR spectroscopy, and electrochemical methods. Penicillin G did not show any detectable interactions with Cu2+. Ampicillin, amoxicillin and cephalexin formed stable colored complexes with octahedral coordination environment of Cu2+ with tetragonal distortion, and primary amine group as the site of coordinate bond formation. These β-lactams increased the solubility of Cu2+ in the phosphate buffer. Ceftazidime and Cu2+ formed a complex with a similar geometry and gave rise to an organic radical. Ceftriaxone-Cu2+ complex appears to exhibit different geometry. All complexes showed 1:1 stoichiometry. Cefaclor reduced Cu2+ to Cu1+ that further reacted with molecular oxygen to produce hydrogen peroxide. Finally, meropenem underwent degradation in the presence of copper. The analysis of activity against Escherichia coli and Staphylococcus aureus showed that the effects of meropenem, amoxicillin, ampicillin, and ceftriaxone were significantly hindered in the presence of copper ions. The interactions with copper ions should be taken into account regarding the problem of antibiotic resistance and in the selection of the most efficient antimicrobial therapy for patients with altered copper homeostasis. © 2018 Elsevier Inc.",
publisher = "Elsevier",
journal = "Free Radical Biology and Medicine",
title = "Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity",
volume = "129",
pages = "279-285",
doi = "10.1016/j.freeradbiomed.2018.09.038",
url = "Kon_1320"
}
Božić, B., Korać, J., Stanković, D., Stanić, M., Romanović, M., Pristov-Bogdanović, J., Spasić, S., Popović-Bijelić, A., Spasojević, I.,& Bajčetić, M.. (2018). Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity. in Free Radical Biology and Medicine
Elsevier., 129, 279-285.
https://doi.org/10.1016/j.freeradbiomed.2018.09.038
Kon_1320
Božić B, Korać J, Stanković D, Stanić M, Romanović M, Pristov-Bogdanović J, Spasić S, Popović-Bijelić A, Spasojević I, Bajčetić M. Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity. in Free Radical Biology and Medicine. 2018;129:279-285.
doi:10.1016/j.freeradbiomed.2018.09.038
Kon_1320 .
Božić, Bojana, Korać, Jelena, Stanković, Dalibor, Stanić, Marina, Romanović, Mima, Pristov-Bogdanović, Jelena, Spasić, Snežana, Popović-Bijelić, Ana, Spasojević, Ivan, Bajčetić, Milica, "Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity" in Free Radical Biology and Medicine, 129 (2018):279-285,
https://doi.org/10.1016/j.freeradbiomed.2018.09.038 .,
Kon_1320 .
1
5
4
6

Supplementary data for the article: Božić, B.; Korać, J.; Stanković, D. M.; Stanić, M.; Romanović, M.; Pristov, J. B.; Spasić, S.; Popović-Bijelić, A.; Spasojević, I.; Bajčetić, M. Coordination and Redox Interactions of β-Lactam Antibiotics with Cu2+ in Physiological Settings and the Impact on Antibacterial Activity. Free Radical Biology and Medicine 2018, 129, 279–285. https://doi.org/10.1016/j.freeradbiomed.2018.09.038

Božić, Bojana; Korać, Jelena; Stanković, Dalibor; Stanić, Marina; Romanović, Mima; Pristov-Bogdanović, Jelena; Spasić, Snežana; Popović-Bijelić, Ana; Spasojević, Ivan; Bajčetić, Milica

(2018)

TY  - DATA
AU  - Božić, Bojana
AU  - Korać, Jelena
AU  - Stanković, Dalibor
AU  - Stanić, Marina
AU  - Romanović, Mima
AU  - Pristov-Bogdanović, Jelena
AU  - Spasić, Snežana
AU  - Popović-Bijelić, Ana
AU  - Spasojević, Ivan
AU  - Bajčetić, Milica
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2941
T2  - Free Radical Biology and Medicine
T1  - Supplementary data for the article: Božić, B.; Korać, J.; Stanković, D. M.; Stanić, M.; Romanović, M.; Pristov, J. B.; Spasić, S.; Popović-Bijelić, A.; Spasojević, I.; Bajčetić, M. Coordination and Redox Interactions of β-Lactam Antibiotics with Cu2+ in Physiological Settings and the Impact on Antibacterial Activity. Free Radical Biology and Medicine 2018, 129, 279–285. https://doi.org/10.1016/j.freeradbiomed.2018.09.038
VL  - 129
SP  - 279
EP  - 285
UR  - Kon_1320
UR  - https://hdl.handle.net/21.15107/rcub_cherry_2941
ER  - 
@misc{
author = "Božić, Bojana and Korać, Jelena and Stanković, Dalibor and Stanić, Marina and Romanović, Mima and Pristov-Bogdanović, Jelena and Spasić, Snežana and Popović-Bijelić, Ana and Spasojević, Ivan and Bajčetić, Milica",
year = "2018",
journal = "Free Radical Biology and Medicine",
title = "Supplementary data for the article: Božić, B.; Korać, J.; Stanković, D. M.; Stanić, M.; Romanović, M.; Pristov, J. B.; Spasić, S.; Popović-Bijelić, A.; Spasojević, I.; Bajčetić, M. Coordination and Redox Interactions of β-Lactam Antibiotics with Cu2+ in Physiological Settings and the Impact on Antibacterial Activity. Free Radical Biology and Medicine 2018, 129, 279–285. https://doi.org/10.1016/j.freeradbiomed.2018.09.038",
volume = "129",
pages = "279-285",
url = "Kon_1320, https://hdl.handle.net/21.15107/rcub_cherry_2941"
}
Božić, B., Korać, J., Stanković, D., Stanić, M., Romanović, M., Pristov-Bogdanović, J., Spasić, S., Popović-Bijelić, A., Spasojević, I.,& Bajčetić, M.. (2018). Supplementary data for the article: Božić, B.; Korać, J.; Stanković, D. M.; Stanić, M.; Romanović, M.; Pristov, J. B.; Spasić, S.; Popović-Bijelić, A.; Spasojević, I.; Bajčetić, M. Coordination and Redox Interactions of β-Lactam Antibiotics with Cu2+ in Physiological Settings and the Impact on Antibacterial Activity. Free Radical Biology and Medicine 2018, 129, 279–285. https://doi.org/10.1016/j.freeradbiomed.2018.09.038. in Free Radical Biology and Medicine, 129, 279-285.
Kon_1320
Božić B, Korać J, Stanković D, Stanić M, Romanović M, Pristov-Bogdanović J, Spasić S, Popović-Bijelić A, Spasojević I, Bajčetić M. Supplementary data for the article: Božić, B.; Korać, J.; Stanković, D. M.; Stanić, M.; Romanović, M.; Pristov, J. B.; Spasić, S.; Popović-Bijelić, A.; Spasojević, I.; Bajčetić, M. Coordination and Redox Interactions of β-Lactam Antibiotics with Cu2+ in Physiological Settings and the Impact on Antibacterial Activity. Free Radical Biology and Medicine 2018, 129, 279–285. https://doi.org/10.1016/j.freeradbiomed.2018.09.038. in Free Radical Biology and Medicine. 2018;129:279-285.
Kon_1320 .
Božić, Bojana, Korać, Jelena, Stanković, Dalibor, Stanić, Marina, Romanović, Mima, Pristov-Bogdanović, Jelena, Spasić, Snežana, Popović-Bijelić, Ana, Spasojević, Ivan, Bajčetić, Milica, "Supplementary data for the article: Božić, B.; Korać, J.; Stanković, D. M.; Stanić, M.; Romanović, M.; Pristov, J. B.; Spasić, S.; Popović-Bijelić, A.; Spasojević, I.; Bajčetić, M. Coordination and Redox Interactions of β-Lactam Antibiotics with Cu2+ in Physiological Settings and the Impact on Antibacterial Activity. Free Radical Biology and Medicine 2018, 129, 279–285. https://doi.org/10.1016/j.freeradbiomed.2018.09.038" in Free Radical Biology and Medicine, 129 (2018):279-285,
Kon_1320 .

Electrochemical monitoring of the breast milk quality

Lugonja, Nikoleta; Stanković, Dalibor; Miličić, Biljana; Spasić, Snežana; Marinković, Vesna; Vrvić, Miroslav M.

(Elsevier Sci Ltd, Oxford, 2018)

TY  - JOUR
AU  - Lugonja, Nikoleta
AU  - Stanković, Dalibor
AU  - Miličić, Biljana
AU  - Spasić, Snežana
AU  - Marinković, Vesna
AU  - Vrvić, Miroslav M.
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2528
AB  - The electrochemical techniques were used to determine the total antioxidant capacity of breast milks and the results were compared with a commonly used spectrophotometric (2,2-diphenyl-1-picrylhydrazyl, DPPH) method. Breast milk from mothers of preterm infants was monitored in three lactation phases and after storage of expressed milk by monitoring changes in the total antioxidant capacity over a two year period. Statistical analysis showed there was no significant difference between the ability of the three methods to detect changes in breast milk after storage. Either of the electrochemical techniques studied could be successfully used to replace the time-consuming spectrophotometric method and can be applied to clinical trials.
PB  - Elsevier Sci Ltd, Oxford
T2  - Food Chemistry
T1  - Electrochemical monitoring of the breast milk quality
VL  - 240
SP  - 567
EP  - 572
DO  - 10.1016/j.foodchem.2017.07.164
UR  - Kon_3344
ER  - 
@article{
author = "Lugonja, Nikoleta and Stanković, Dalibor and Miličić, Biljana and Spasić, Snežana and Marinković, Vesna and Vrvić, Miroslav M.",
year = "2018",
abstract = "The electrochemical techniques were used to determine the total antioxidant capacity of breast milks and the results were compared with a commonly used spectrophotometric (2,2-diphenyl-1-picrylhydrazyl, DPPH) method. Breast milk from mothers of preterm infants was monitored in three lactation phases and after storage of expressed milk by monitoring changes in the total antioxidant capacity over a two year period. Statistical analysis showed there was no significant difference between the ability of the three methods to detect changes in breast milk after storage. Either of the electrochemical techniques studied could be successfully used to replace the time-consuming spectrophotometric method and can be applied to clinical trials.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Food Chemistry",
title = "Electrochemical monitoring of the breast milk quality",
volume = "240",
pages = "567-572",
doi = "10.1016/j.foodchem.2017.07.164",
url = "Kon_3344"
}
Lugonja, N., Stanković, D., Miličić, B., Spasić, S., Marinković, V.,& Vrvić, M. M.. (2018). Electrochemical monitoring of the breast milk quality. in Food Chemistry
Elsevier Sci Ltd, Oxford., 240, 567-572.
https://doi.org/10.1016/j.foodchem.2017.07.164
Kon_3344
Lugonja N, Stanković D, Miličić B, Spasić S, Marinković V, Vrvić MM. Electrochemical monitoring of the breast milk quality. in Food Chemistry. 2018;240:567-572.
doi:10.1016/j.foodchem.2017.07.164
Kon_3344 .
Lugonja, Nikoleta, Stanković, Dalibor, Miličić, Biljana, Spasić, Snežana, Marinković, Vesna, Vrvić, Miroslav M., "Electrochemical monitoring of the breast milk quality" in Food Chemistry, 240 (2018):567-572,
https://doi.org/10.1016/j.foodchem.2017.07.164 .,
Kon_3344 .
9
8
11

Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity

Božić, Bojana; Korać, Jelena; Stanković, Dalibor; Stanić, Marina; Romanović, Mima; Pristov-Bogdanović, Jelena; Spasić, Snežana; Popović-Bijelić, Ana; Spasojević, Ivan; Bajčetić, Milica

(Elsevier, 2018)

TY  - JOUR
AU  - Božić, Bojana
AU  - Korać, Jelena
AU  - Stanković, Dalibor
AU  - Stanić, Marina
AU  - Romanović, Mima
AU  - Pristov-Bogdanović, Jelena
AU  - Spasić, Snežana
AU  - Popović-Bijelić, Ana
AU  - Spasojević, Ivan
AU  - Bajčetić, Milica
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/349
AB  - An increase in the copper pool in body fluids has been related to a number of pathological conditions, including infections. Copper ions may affect antibiotics via the formation of coordination bonds and/or redox reactions. Herein, we analyzed the interactions of Cu2+ with eight β-lactam antibiotics using UV–Vis spectrophotometry, EPR spectroscopy, and electrochemical methods. Penicillin G did not show any detectable interactions with Cu2+. Ampicillin, amoxicillin and cephalexin formed stable colored complexes with octahedral coordination environment of Cu2+ with tetragonal distortion, and primary amine group as the site of coordinate bond formation. These β-lactams increased the solubility of Cu2+ in the phosphate buffer. Ceftazidime and Cu2+ formed a complex with a similar geometry and gave rise to an organic radical. Ceftriaxone-Cu2+ complex appears to exhibit different geometry. All complexes showed 1:1 stoichiometry. Cefaclor reduced Cu2+ to Cu1+ that further reacted with molecular oxygen to produce hydrogen peroxide. Finally, meropenem underwent degradation in the presence of copper. The analysis of activity against Escherichia coli and Staphylococcus aureus showed that the effects of meropenem, amoxicillin, ampicillin, and ceftriaxone were significantly hindered in the presence of copper ions. The interactions with copper ions should be taken into account regarding the problem of antibiotic resistance and in the selection of the most efficient antimicrobial therapy for patients with altered copper homeostasis. © 2018 Elsevier Inc.
PB  - Elsevier
T2  - Free Radical Biology and Medicine
T1  - Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity
VL  - 129
SP  - 279
EP  - 285
DO  - 10.1016/j.freeradbiomed.2018.09.038
UR  - Kon_1320
ER  - 
@article{
author = "Božić, Bojana and Korać, Jelena and Stanković, Dalibor and Stanić, Marina and Romanović, Mima and Pristov-Bogdanović, Jelena and Spasić, Snežana and Popović-Bijelić, Ana and Spasojević, Ivan and Bajčetić, Milica",
year = "2018",
abstract = "An increase in the copper pool in body fluids has been related to a number of pathological conditions, including infections. Copper ions may affect antibiotics via the formation of coordination bonds and/or redox reactions. Herein, we analyzed the interactions of Cu2+ with eight β-lactam antibiotics using UV–Vis spectrophotometry, EPR spectroscopy, and electrochemical methods. Penicillin G did not show any detectable interactions with Cu2+. Ampicillin, amoxicillin and cephalexin formed stable colored complexes with octahedral coordination environment of Cu2+ with tetragonal distortion, and primary amine group as the site of coordinate bond formation. These β-lactams increased the solubility of Cu2+ in the phosphate buffer. Ceftazidime and Cu2+ formed a complex with a similar geometry and gave rise to an organic radical. Ceftriaxone-Cu2+ complex appears to exhibit different geometry. All complexes showed 1:1 stoichiometry. Cefaclor reduced Cu2+ to Cu1+ that further reacted with molecular oxygen to produce hydrogen peroxide. Finally, meropenem underwent degradation in the presence of copper. The analysis of activity against Escherichia coli and Staphylococcus aureus showed that the effects of meropenem, amoxicillin, ampicillin, and ceftriaxone were significantly hindered in the presence of copper ions. The interactions with copper ions should be taken into account regarding the problem of antibiotic resistance and in the selection of the most efficient antimicrobial therapy for patients with altered copper homeostasis. © 2018 Elsevier Inc.",
publisher = "Elsevier",
journal = "Free Radical Biology and Medicine",
title = "Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity",
volume = "129",
pages = "279-285",
doi = "10.1016/j.freeradbiomed.2018.09.038",
url = "Kon_1320"
}
Božić, B., Korać, J., Stanković, D., Stanić, M., Romanović, M., Pristov-Bogdanović, J., Spasić, S., Popović-Bijelić, A., Spasojević, I.,& Bajčetić, M.. (2018). Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity. in Free Radical Biology and Medicine
Elsevier., 129, 279-285.
https://doi.org/10.1016/j.freeradbiomed.2018.09.038
Kon_1320
Božić B, Korać J, Stanković D, Stanić M, Romanović M, Pristov-Bogdanović J, Spasić S, Popović-Bijelić A, Spasojević I, Bajčetić M. Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity. in Free Radical Biology and Medicine. 2018;129:279-285.
doi:10.1016/j.freeradbiomed.2018.09.038
Kon_1320 .
Božić, Bojana, Korać, Jelena, Stanković, Dalibor, Stanić, Marina, Romanović, Mima, Pristov-Bogdanović, Jelena, Spasić, Snežana, Popović-Bijelić, Ana, Spasojević, Ivan, Bajčetić, Milica, "Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity" in Free Radical Biology and Medicine, 129 (2018):279-285,
https://doi.org/10.1016/j.freeradbiomed.2018.09.038 .,
Kon_1320 .
1
5
4
6

Zinc concentrations in human milk and infant serum during the first six months of lactation

Đurović, Dijana; Milisavljevic, Branka; Mugosa, Boban; Lugonja, Nikoleta; Miletić, Srđan B.; Spasić, Snežana; Vrvić, Miroslav

(Elsevier Gmbh, Urban & Fischer Verlag, Jena, 2017)

TY  - JOUR
AU  - Đurović, Dijana
AU  - Milisavljevic, Branka
AU  - Mugosa, Boban
AU  - Lugonja, Nikoleta
AU  - Miletić, Srđan B.
AU  - Spasić, Snežana
AU  - Vrvić, Miroslav
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4966
AB  - Normal supply of zinc to the newborn via milk is essential for normal development. Using ICP-OES, we analyzed changes in the level of Zn in milk and infant serum in the neonatal period (Day 1 and Day 28 post partum) and at 6 months after delivery, in the cohort of 60 mothers and exclusively breastfed babies. Zn level in the serum showed increase (significant at 6 months) during this period (mg/mL): Day 1: 0.52 +/- 0.12; Day 28; 0.59 +/- 0.19; 6 months: 0.68 +/- 0.28. The concentration of Zn in the milk showed an opposite (decreasing) trend during the follow up: Day 1: 4.70 +/- 1.74 mg/L; Day 28: 2.65 +/- 1.06; 6 months: 0.46 +/- 0.36. A significant negative correlation was established between serum and milk [Zn] at day 28 (R = -0.338; p = 0.008), whereas a positive correlation was found at 6 months between these parameters (R = 0.306; p = 0.018). There was no significant correlation between [Zn] in the milk and serum and infants' body mass, mothers' age and mass at delivery. The level of Zn in the milk at 6 months of lactation is not sufficient to meet the recommended values. This implies that in Serbian population, Zn supplementation might be needed in the later phase of lactation.
PB  - Elsevier Gmbh, Urban & Fischer Verlag, Jena
T2  - Journal of Trace Elements in Medicine and Biology
T1  - Zinc concentrations in human milk and infant serum during the first six months of lactation
VL  - 41
SP  - 75
EP  - 78
DO  - 10.1016/j.jtemb.2017.02.012
ER  - 
@article{
author = "Đurović, Dijana and Milisavljevic, Branka and Mugosa, Boban and Lugonja, Nikoleta and Miletić, Srđan B. and Spasić, Snežana and Vrvić, Miroslav",
year = "2017",
abstract = "Normal supply of zinc to the newborn via milk is essential for normal development. Using ICP-OES, we analyzed changes in the level of Zn in milk and infant serum in the neonatal period (Day 1 and Day 28 post partum) and at 6 months after delivery, in the cohort of 60 mothers and exclusively breastfed babies. Zn level in the serum showed increase (significant at 6 months) during this period (mg/mL): Day 1: 0.52 +/- 0.12; Day 28; 0.59 +/- 0.19; 6 months: 0.68 +/- 0.28. The concentration of Zn in the milk showed an opposite (decreasing) trend during the follow up: Day 1: 4.70 +/- 1.74 mg/L; Day 28: 2.65 +/- 1.06; 6 months: 0.46 +/- 0.36. A significant negative correlation was established between serum and milk [Zn] at day 28 (R = -0.338; p = 0.008), whereas a positive correlation was found at 6 months between these parameters (R = 0.306; p = 0.018). There was no significant correlation between [Zn] in the milk and serum and infants' body mass, mothers' age and mass at delivery. The level of Zn in the milk at 6 months of lactation is not sufficient to meet the recommended values. This implies that in Serbian population, Zn supplementation might be needed in the later phase of lactation.",
publisher = "Elsevier Gmbh, Urban & Fischer Verlag, Jena",
journal = "Journal of Trace Elements in Medicine and Biology",
title = "Zinc concentrations in human milk and infant serum during the first six months of lactation",
volume = "41",
pages = "75-78",
doi = "10.1016/j.jtemb.2017.02.012"
}
Đurović, D., Milisavljevic, B., Mugosa, B., Lugonja, N., Miletić, S. B., Spasić, S.,& Vrvić, M.. (2017). Zinc concentrations in human milk and infant serum during the first six months of lactation. in Journal of Trace Elements in Medicine and Biology
Elsevier Gmbh, Urban & Fischer Verlag, Jena., 41, 75-78.
https://doi.org/10.1016/j.jtemb.2017.02.012
Đurović D, Milisavljevic B, Mugosa B, Lugonja N, Miletić SB, Spasić S, Vrvić M. Zinc concentrations in human milk and infant serum during the first six months of lactation. in Journal of Trace Elements in Medicine and Biology. 2017;41:75-78.
doi:10.1016/j.jtemb.2017.02.012 .
Đurović, Dijana, Milisavljevic, Branka, Mugosa, Boban, Lugonja, Nikoleta, Miletić, Srđan B., Spasić, Snežana, Vrvić, Miroslav, "Zinc concentrations in human milk and infant serum during the first six months of lactation" in Journal of Trace Elements in Medicine and Biology, 41 (2017):75-78,
https://doi.org/10.1016/j.jtemb.2017.02.012 . .
9
7
9

Antioxidative Activity of Colostrum and Human Milk: Effects of Pasteurization and Storage

Marinković, Vesna; Rankovic-Janevski, Milica; Spasić, Snežana; Nikolić-Kokić, Aleksandra; Lugonja, Nikoleta; Đurović, Dijana; Miletić, Srđan B.; Vrvić, Miroslav; Spasojević, Ivan

(Lippincott Williams & Wilkins, Philadelphia, 2016)

TY  - JOUR
AU  - Marinković, Vesna
AU  - Rankovic-Janevski, Milica
AU  - Spasić, Snežana
AU  - Nikolić-Kokić, Aleksandra
AU  - Lugonja, Nikoleta
AU  - Đurović, Dijana
AU  - Miletić, Srđan B.
AU  - Vrvić, Miroslav
AU  - Spasojević, Ivan
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4973
AB  - Objectives: Milk banks collect, pasteurize, and freeze/store human milk. The processing may alter redox properties of milk, but the effects have not been fully examined. Methods: We collected 10 mature milk and 10 colostrum samples and applied a battery of biochemical assays and electron paramagnetic resonance spectroscopy to inspect changes that milk undergoes with pasteurization and 30 days storage at -20 degrees C. Results: Pasteurization and storage of raw milk did not affect total nonenzymatic antioxidative capacity, but specific components and features were altered. Urate radical and ascorbyl radical emerge as products of exposure of milk to hydroxyl radical-generating system. Processing shifted the load of antioxidative activity from ascorbate to urate and lowered the capacity of milk to diminish hydroxyl radical. Pasteurization caused a significant drop in the activity of 2 major antioxidative enzymes-superoxide dismutase and glutathione peroxidase, whereas freezing/storage of raw milk affected only superoxide dismutase. Colostrum showed drastically higher total nonenzymatic antioxidative capacity, hydroxyl radical scavenging ability, and glutathione reductase activity compared with mature milk. Conclusions: Pasteurization and storage affect nonenzymatic and enzymatic antioxidative agents in human milk. It appears that nonenzymatic antioxidative systems in colostrum and milk are different. The effects of processing may be partially compensated by fortification/spiking with ascorbate before use.
PB  - Lippincott Williams & Wilkins, Philadelphia
T2  - Journal of Pediatric Gastroenterology and Nutrition
T1  - Antioxidative Activity of Colostrum and Human Milk: Effects of Pasteurization and Storage
VL  - 62
IS  - 6
SP  - 901
EP  - 906
DO  - 10.1097/MPG.0000000000001090
ER  - 
@article{
author = "Marinković, Vesna and Rankovic-Janevski, Milica and Spasić, Snežana and Nikolić-Kokić, Aleksandra and Lugonja, Nikoleta and Đurović, Dijana and Miletić, Srđan B. and Vrvić, Miroslav and Spasojević, Ivan",
year = "2016",
abstract = "Objectives: Milk banks collect, pasteurize, and freeze/store human milk. The processing may alter redox properties of milk, but the effects have not been fully examined. Methods: We collected 10 mature milk and 10 colostrum samples and applied a battery of biochemical assays and electron paramagnetic resonance spectroscopy to inspect changes that milk undergoes with pasteurization and 30 days storage at -20 degrees C. Results: Pasteurization and storage of raw milk did not affect total nonenzymatic antioxidative capacity, but specific components and features were altered. Urate radical and ascorbyl radical emerge as products of exposure of milk to hydroxyl radical-generating system. Processing shifted the load of antioxidative activity from ascorbate to urate and lowered the capacity of milk to diminish hydroxyl radical. Pasteurization caused a significant drop in the activity of 2 major antioxidative enzymes-superoxide dismutase and glutathione peroxidase, whereas freezing/storage of raw milk affected only superoxide dismutase. Colostrum showed drastically higher total nonenzymatic antioxidative capacity, hydroxyl radical scavenging ability, and glutathione reductase activity compared with mature milk. Conclusions: Pasteurization and storage affect nonenzymatic and enzymatic antioxidative agents in human milk. It appears that nonenzymatic antioxidative systems in colostrum and milk are different. The effects of processing may be partially compensated by fortification/spiking with ascorbate before use.",
publisher = "Lippincott Williams & Wilkins, Philadelphia",
journal = "Journal of Pediatric Gastroenterology and Nutrition",
title = "Antioxidative Activity of Colostrum and Human Milk: Effects of Pasteurization and Storage",
volume = "62",
number = "6",
pages = "901-906",
doi = "10.1097/MPG.0000000000001090"
}
Marinković, V., Rankovic-Janevski, M., Spasić, S., Nikolić-Kokić, A., Lugonja, N., Đurović, D., Miletić, S. B., Vrvić, M.,& Spasojević, I.. (2016). Antioxidative Activity of Colostrum and Human Milk: Effects of Pasteurization and Storage. in Journal of Pediatric Gastroenterology and Nutrition
Lippincott Williams & Wilkins, Philadelphia., 62(6), 901-906.
https://doi.org/10.1097/MPG.0000000000001090
Marinković V, Rankovic-Janevski M, Spasić S, Nikolić-Kokić A, Lugonja N, Đurović D, Miletić SB, Vrvić M, Spasojević I. Antioxidative Activity of Colostrum and Human Milk: Effects of Pasteurization and Storage. in Journal of Pediatric Gastroenterology and Nutrition. 2016;62(6):901-906.
doi:10.1097/MPG.0000000000001090 .
Marinković, Vesna, Rankovic-Janevski, Milica, Spasić, Snežana, Nikolić-Kokić, Aleksandra, Lugonja, Nikoleta, Đurović, Dijana, Miletić, Srđan B., Vrvić, Miroslav, Spasojević, Ivan, "Antioxidative Activity of Colostrum and Human Milk: Effects of Pasteurization and Storage" in Journal of Pediatric Gastroenterology and Nutrition, 62, no. 6 (2016):901-906,
https://doi.org/10.1097/MPG.0000000000001090 . .
34
28
34

The Effect of Humic Acids on Zymogenous Microbial Consortia Growth

Miletić, Srđan B.; Spasić, Snežana; Avdalović, Jelena; Beškoski, Vladimir; Ilić, Mila V.; Gojgić-Cvijović, Gordana D.; Vrvić, Miroslav M.

(Wiley-Blackwell, Hoboken, 2014)

TY  - JOUR
AU  - Miletić, Srđan B.
AU  - Spasić, Snežana
AU  - Avdalović, Jelena
AU  - Beškoski, Vladimir
AU  - Ilić, Mila V.
AU  - Gojgić-Cvijović, Gordana D.
AU  - Vrvić, Miroslav M.
PY  - 2014
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1852
AB  - This paper describes experiments with standard humic acids (HA-S) and humic acids (HA) isolated from soil that was contaminated with mazut and treated with a consortium of microorganisms for the process of bioremediation (HA-E). Both acids inhibited the toxicity of ferric chloride and increased the growth of a zymogenous microbial consortia compared with controls. Electron paramagnetic resonance spectroscopy showed that HA-S and HA-E exhibit high anti-oxidative activity involving free radical scavenging and iron sequestration. HA additionally promote microbial consortium growth by providing protection from oxidative stress.
PB  - Wiley-Blackwell, Hoboken
T2  - CLEAN - Soil Air Water
T1  - The Effect of Humic Acids on Zymogenous Microbial Consortia Growth
VL  - 42
IS  - 9
SP  - 1280
EP  - 1283
DO  - 10.1002/clen.201300034
UR  - Kon_2735
ER  - 
@article{
author = "Miletić, Srđan B. and Spasić, Snežana and Avdalović, Jelena and Beškoski, Vladimir and Ilić, Mila V. and Gojgić-Cvijović, Gordana D. and Vrvić, Miroslav M.",
year = "2014",
abstract = "This paper describes experiments with standard humic acids (HA-S) and humic acids (HA) isolated from soil that was contaminated with mazut and treated with a consortium of microorganisms for the process of bioremediation (HA-E). Both acids inhibited the toxicity of ferric chloride and increased the growth of a zymogenous microbial consortia compared with controls. Electron paramagnetic resonance spectroscopy showed that HA-S and HA-E exhibit high anti-oxidative activity involving free radical scavenging and iron sequestration. HA additionally promote microbial consortium growth by providing protection from oxidative stress.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "CLEAN - Soil Air Water",
title = "The Effect of Humic Acids on Zymogenous Microbial Consortia Growth",
volume = "42",
number = "9",
pages = "1280-1283",
doi = "10.1002/clen.201300034",
url = "Kon_2735"
}
Miletić, S. B., Spasić, S., Avdalović, J., Beškoski, V., Ilić, M. V., Gojgić-Cvijović, G. D.,& Vrvić, M. M.. (2014). The Effect of Humic Acids on Zymogenous Microbial Consortia Growth. in CLEAN - Soil Air Water
Wiley-Blackwell, Hoboken., 42(9), 1280-1283.
https://doi.org/10.1002/clen.201300034
Kon_2735
Miletić SB, Spasić S, Avdalović J, Beškoski V, Ilić MV, Gojgić-Cvijović GD, Vrvić MM. The Effect of Humic Acids on Zymogenous Microbial Consortia Growth. in CLEAN - Soil Air Water. 2014;42(9):1280-1283.
doi:10.1002/clen.201300034
Kon_2735 .
Miletić, Srđan B., Spasić, Snežana, Avdalović, Jelena, Beškoski, Vladimir, Ilić, Mila V., Gojgić-Cvijović, Gordana D., Vrvić, Miroslav M., "The Effect of Humic Acids on Zymogenous Microbial Consortia Growth" in CLEAN - Soil Air Water, 42, no. 9 (2014):1280-1283,
https://doi.org/10.1002/clen.201300034 .,
Kon_2735 .
1
3
3

Simultaneous bioremediation and soilification-new technology for recovery ash dump of thermoelectric power plants

Avdalović, Jelena; Milić, Jelena; Ilić, Mila; Miletić, Srđan B.; Beškoski, Vladimir; Gojgić-Cvijović, Gordana; Spasić, Snežana; Potkonjak, Branislav; Jakovljević, Dragica; Vrvić, Miroslav

(Belgrade : Association for the Development and use soill and landfills, 2014)

TY  - CONF
AU  - Avdalović, Jelena
AU  - Milić, Jelena
AU  - Ilić, Mila
AU  - Miletić, Srđan B.
AU  - Beškoski, Vladimir
AU  - Gojgić-Cvijović, Gordana
AU  - Spasić, Snežana
AU  - Potkonjak, Branislav
AU  - Jakovljević, Dragica
AU  - Vrvić, Miroslav
PY  - 2014
UR  - http://www.chem.bg.ac.rs/~p43004/ref/2014/2014_zrenjanin_javdalovic.pdf
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4954
PB  - Belgrade : Association for the Development and use soill and landfills
C3  - Planning and lend use and landfills in terms of sustainable development and new remediation technologies “Soil 2014”, Proceedings
T1  - Simultaneous bioremediation and soilification-new technology for recovery ash dump of thermoelectric power plants
SP  - 11
EP  - 15
UR  - https://hdl.handle.net/21.15107/rcub_cer_3955
ER  - 
@conference{
author = "Avdalović, Jelena and Milić, Jelena and Ilić, Mila and Miletić, Srđan B. and Beškoski, Vladimir and Gojgić-Cvijović, Gordana and Spasić, Snežana and Potkonjak, Branislav and Jakovljević, Dragica and Vrvić, Miroslav",
year = "2014",
publisher = "Belgrade : Association for the Development and use soill and landfills",
journal = "Planning and lend use and landfills in terms of sustainable development and new remediation technologies “Soil 2014”, Proceedings",
title = "Simultaneous bioremediation and soilification-new technology for recovery ash dump of thermoelectric power plants",
pages = "11-15",
url = "https://hdl.handle.net/21.15107/rcub_cer_3955"
}
Avdalović, J., Milić, J., Ilić, M., Miletić, S. B., Beškoski, V., Gojgić-Cvijović, G., Spasić, S., Potkonjak, B., Jakovljević, D.,& Vrvić, M.. (2014). Simultaneous bioremediation and soilification-new technology for recovery ash dump of thermoelectric power plants. in Planning and lend use and landfills in terms of sustainable development and new remediation technologies “Soil 2014”, Proceedings
Belgrade : Association for the Development and use soill and landfills., 11-15.
https://hdl.handle.net/21.15107/rcub_cer_3955
Avdalović J, Milić J, Ilić M, Miletić SB, Beškoski V, Gojgić-Cvijović G, Spasić S, Potkonjak B, Jakovljević D, Vrvić M. Simultaneous bioremediation and soilification-new technology for recovery ash dump of thermoelectric power plants. in Planning and lend use and landfills in terms of sustainable development and new remediation technologies “Soil 2014”, Proceedings. 2014;:11-15.
https://hdl.handle.net/21.15107/rcub_cer_3955 .
Avdalović, Jelena, Milić, Jelena, Ilić, Mila, Miletić, Srđan B., Beškoski, Vladimir, Gojgić-Cvijović, Gordana, Spasić, Snežana, Potkonjak, Branislav, Jakovljević, Dragica, Vrvić, Miroslav, "Simultaneous bioremediation and soilification-new technology for recovery ash dump of thermoelectric power plants" in Planning and lend use and landfills in terms of sustainable development and new remediation technologies “Soil 2014”, Proceedings (2014):11-15,
https://hdl.handle.net/21.15107/rcub_cer_3955 .

Comparative Electrochemical Determination of Total Antioxidant Activity in Infant Formula with Breast Milk

Lugonja, Nikoleta; Stanković, Dalibor; Spasić, Snežana; Roglić, Goran; Manojlović, Dragan D.; Vrvić, Miroslav M.

(Springer, New York, 2014)

TY  - JOUR
AU  - Lugonja, Nikoleta
AU  - Stanković, Dalibor
AU  - Spasić, Snežana
AU  - Roglić, Goran
AU  - Manojlović, Dragan D.
AU  - Vrvić, Miroslav M.
PY  - 2014
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1487
AB  - The aim of this study is to investigate the significance of breast milk and infant formula in the prevention of oxidative stress, by electrochemical determination of the total antioxidant potential, demonstrating the relationship between the antioxidant capacity of milk and postnatal age. Human breast milk, commercial UHT milk, and infant formulas supplemented with prebiotics were used. Samples were diluted in phosphate buffer solution, and the total antioxidant activity was potentiometrically measured by the iodine/iodide redox couple with the Pt Fisher electrode as a working electrode and saturated calomel as a reference electrode. Cyclic voltammograms and differential pulse voltammograms were recorded with the glassy carbon electrode as the working electrode, an accessory platinum electrode, and an Ag/AgCl reference electrode. The potentiometric measurement indicates that human breast milk has the highest redox potential, while the commercial UHT milk has very low potential. Infant formulas also have high potential. The main advantage of electrochemical methods used to assess the total antioxidant activity of milk was that they directly monitored the electron-donating ability of the compounds and could be used for the quantitative analysis of the total antioxidants of different types of milk.
PB  - Springer, New York
T2  - Food Analytical Methods
T1  - Comparative Electrochemical Determination of Total Antioxidant Activity in Infant Formula with Breast Milk
VL  - 7
IS  - 2
SP  - 337
EP  - 344
DO  - 10.1007/s12161-013-9631-7
UR  - Kon_2607
ER  - 
@article{
author = "Lugonja, Nikoleta and Stanković, Dalibor and Spasić, Snežana and Roglić, Goran and Manojlović, Dragan D. and Vrvić, Miroslav M.",
year = "2014",
abstract = "The aim of this study is to investigate the significance of breast milk and infant formula in the prevention of oxidative stress, by electrochemical determination of the total antioxidant potential, demonstrating the relationship between the antioxidant capacity of milk and postnatal age. Human breast milk, commercial UHT milk, and infant formulas supplemented with prebiotics were used. Samples were diluted in phosphate buffer solution, and the total antioxidant activity was potentiometrically measured by the iodine/iodide redox couple with the Pt Fisher electrode as a working electrode and saturated calomel as a reference electrode. Cyclic voltammograms and differential pulse voltammograms were recorded with the glassy carbon electrode as the working electrode, an accessory platinum electrode, and an Ag/AgCl reference electrode. The potentiometric measurement indicates that human breast milk has the highest redox potential, while the commercial UHT milk has very low potential. Infant formulas also have high potential. The main advantage of electrochemical methods used to assess the total antioxidant activity of milk was that they directly monitored the electron-donating ability of the compounds and could be used for the quantitative analysis of the total antioxidants of different types of milk.",
publisher = "Springer, New York",
journal = "Food Analytical Methods",
title = "Comparative Electrochemical Determination of Total Antioxidant Activity in Infant Formula with Breast Milk",
volume = "7",
number = "2",
pages = "337-344",
doi = "10.1007/s12161-013-9631-7",
url = "Kon_2607"
}
Lugonja, N., Stanković, D., Spasić, S., Roglić, G., Manojlović, D. D.,& Vrvić, M. M.. (2014). Comparative Electrochemical Determination of Total Antioxidant Activity in Infant Formula with Breast Milk. in Food Analytical Methods
Springer, New York., 7(2), 337-344.
https://doi.org/10.1007/s12161-013-9631-7
Kon_2607
Lugonja N, Stanković D, Spasić S, Roglić G, Manojlović DD, Vrvić MM. Comparative Electrochemical Determination of Total Antioxidant Activity in Infant Formula with Breast Milk. in Food Analytical Methods. 2014;7(2):337-344.
doi:10.1007/s12161-013-9631-7
Kon_2607 .
Lugonja, Nikoleta, Stanković, Dalibor, Spasić, Snežana, Roglić, Goran, Manojlović, Dragan D., Vrvić, Miroslav M., "Comparative Electrochemical Determination of Total Antioxidant Activity in Infant Formula with Breast Milk" in Food Analytical Methods, 7, no. 2 (2014):337-344,
https://doi.org/10.1007/s12161-013-9631-7 .,
Kon_2607 .
12
9
13

Proizvodni mobilni bioreaktor i dobijanje biomase mikroorganizama za bioremedijaciju

Vrvić, Miroslav; Gojgić-Cvijović, Gordana; Jakovljević, Dragica; Spasić, Snežana; Radulović, Milanka; Beškoski, Vladimir; Ilić, Mila; Milić, Jelena; Miletić, Srđan B.; Bajić, Danica

(Projekat TR 20131A, 2010)

TY  - GEN
AU  - Vrvić, Miroslav
AU  - Gojgić-Cvijović, Gordana
AU  - Jakovljević, Dragica
AU  - Spasić, Snežana
AU  - Radulović, Milanka
AU  - Beškoski, Vladimir
AU  - Ilić, Mila
AU  - Milić, Jelena
AU  - Miletić, Srđan B.
AU  - Bajić, Danica
PY  - 2010
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5252
AB  - Tehničko rešenje Mobilni bioreaktor za dobijanje imobilisanih mikroorganizama za bioremedijaciju, se odnosi na nov i ekonomičan postupak u tehnologiji bioremedijacije zemljišta zagadjenih organskim supstancama, prvenstveno naftom i naftnim derivatima. Ovom tehnologijom se rešava problem izlivene nafte, njenih derivata i pratećih zagadjivača pomoću mikroorganizama sa lica mesta na samom mestu zagadjenja. Mobilni bioreaktor je pokretan tako da se na samom mestu kontaminacije umnožava tj. proizvodi velika količina specifičnih mikroorganizama prirodno prisutnih u tom ekosistemu koji zagadjujuću supstancu razlažu i koriste kao hranu. U bioreaktoru se ti mikroorganizmi dodatno optimizuju za konkretno zagadjenje.
PB  - Projekat TR 20131A
T1  - Proizvodni mobilni bioreaktor i dobijanje biomase mikroorganizama za bioremedijaciju
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5252
ER  - 
@misc{
author = "Vrvić, Miroslav and Gojgić-Cvijović, Gordana and Jakovljević, Dragica and Spasić, Snežana and Radulović, Milanka and Beškoski, Vladimir and Ilić, Mila and Milić, Jelena and Miletić, Srđan B. and Bajić, Danica",
year = "2010",
abstract = "Tehničko rešenje Mobilni bioreaktor za dobijanje imobilisanih mikroorganizama za bioremedijaciju, se odnosi na nov i ekonomičan postupak u tehnologiji bioremedijacije zemljišta zagadjenih organskim supstancama, prvenstveno naftom i naftnim derivatima. Ovom tehnologijom se rešava problem izlivene nafte, njenih derivata i pratećih zagadjivača pomoću mikroorganizama sa lica mesta na samom mestu zagadjenja. Mobilni bioreaktor je pokretan tako da se na samom mestu kontaminacije umnožava tj. proizvodi velika količina specifičnih mikroorganizama prirodno prisutnih u tom ekosistemu koji zagadjujuću supstancu razlažu i koriste kao hranu. U bioreaktoru se ti mikroorganizmi dodatno optimizuju za konkretno zagadjenje.",
publisher = "Projekat TR 20131A",
title = "Proizvodni mobilni bioreaktor i dobijanje biomase mikroorganizama za bioremedijaciju",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5252"
}
Vrvić, M., Gojgić-Cvijović, G., Jakovljević, D., Spasić, S., Radulović, M., Beškoski, V., Ilić, M., Milić, J., Miletić, S. B.,& Bajić, D.. (2010). Proizvodni mobilni bioreaktor i dobijanje biomase mikroorganizama za bioremedijaciju. 
Projekat TR 20131A..
https://hdl.handle.net/21.15107/rcub_cherry_5252
Vrvić M, Gojgić-Cvijović G, Jakovljević D, Spasić S, Radulović M, Beškoski V, Ilić M, Milić J, Miletić SB, Bajić D. Proizvodni mobilni bioreaktor i dobijanje biomase mikroorganizama za bioremedijaciju. 2010;.
https://hdl.handle.net/21.15107/rcub_cherry_5252 .
Vrvić, Miroslav, Gojgić-Cvijović, Gordana, Jakovljević, Dragica, Spasić, Snežana, Radulović, Milanka, Beškoski, Vladimir, Ilić, Mila, Milić, Jelena, Miletić, Srđan B., Bajić, Danica, "Proizvodni mobilni bioreaktor i dobijanje biomase mikroorganizama za bioremedijaciju" (2010),
https://hdl.handle.net/21.15107/rcub_cherry_5252 .

Novi proizvod i tehnologija za: „Formulacija pet mlečnih kašica ’Impamil-MIL MLEČNE KAŠICE’ bez glutenskih cerealija i uspostavljanje tehnologije za proizvodnju“ - Na tržištu!

Vrvić, Miroslav; Milić, Jelena; Martinov, O.; Ilić, Mila; Lugonja, Nikoleta; Jakovljević, Dragica; Gojgić-Cvijović, Gordana; Potkonjak, B.; Spasić, Snežana; Miletić, Srđan B.; Beškoski, Vladimir

(University of Belgrade - Institute of Chemistry, Technology and Metallurgy, 2009)

TY  - GEN
AU  - Vrvić, Miroslav
AU  - Milić, Jelena
AU  - Martinov, O.
AU  - Ilić, Mila
AU  - Lugonja, Nikoleta
AU  - Jakovljević, Dragica
AU  - Gojgić-Cvijović, Gordana
AU  - Potkonjak, B.
AU  - Spasić, Snežana
AU  - Miletić, Srđan B.
AU  - Beškoski, Vladimir
PY  - 2009
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5237
AB  - Istraživanje, razvoj i primena rezultata u oblasti dizajniranja, formulisanja, osvajanja tehnologija i proizvodnja i plasman novih dijetetskih proizvoda-namirnica iz kategorija infant formula, prelaznih formula i hrane za decu do 3 godine, kao i specijalnih formulacija za posebne (medicinske) namene u uspešnoj, korektnoj, kolegijalnoj i tolerantnoj saradnji CH-IHTM i “Impamil” doo su dobar zalog za nove primene i stalna usavršavanja postojećih proizvoda prema savremenim rezultatima nauke o biohemiji hrane i ishrane i pedijatrije i zahtevima medjunarodne napredne regulative i legislative.
PB  - University of Belgrade - Institute of Chemistry, Technology and Metallurgy
T1  - Novi proizvod i tehnologija za: „Formulacija pet mlečnih kašica ’Impamil-MIL MLEČNE KAŠICE’ bez glutenskih cerealija i uspostavljanje tehnologije za proizvodnju“ - Na tržištu!
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5237
ER  - 
@misc{
author = "Vrvić, Miroslav and Milić, Jelena and Martinov, O. and Ilić, Mila and Lugonja, Nikoleta and Jakovljević, Dragica and Gojgić-Cvijović, Gordana and Potkonjak, B. and Spasić, Snežana and Miletić, Srđan B. and Beškoski, Vladimir",
year = "2009",
abstract = "Istraživanje, razvoj i primena rezultata u oblasti dizajniranja, formulisanja, osvajanja tehnologija i proizvodnja i plasman novih dijetetskih proizvoda-namirnica iz kategorija infant formula, prelaznih formula i hrane za decu do 3 godine, kao i specijalnih formulacija za posebne (medicinske) namene u uspešnoj, korektnoj, kolegijalnoj i tolerantnoj saradnji CH-IHTM i “Impamil” doo su dobar zalog za nove primene i stalna usavršavanja postojećih proizvoda prema savremenim rezultatima nauke o biohemiji hrane i ishrane i pedijatrije i zahtevima medjunarodne napredne regulative i legislative.",
publisher = "University of Belgrade - Institute of Chemistry, Technology and Metallurgy",
title = "Novi proizvod i tehnologija za: „Formulacija pet mlečnih kašica ’Impamil-MIL MLEČNE KAŠICE’ bez glutenskih cerealija i uspostavljanje tehnologije za proizvodnju“ - Na tržištu!",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5237"
}
Vrvić, M., Milić, J., Martinov, O., Ilić, M., Lugonja, N., Jakovljević, D., Gojgić-Cvijović, G., Potkonjak, B., Spasić, S., Miletić, S. B.,& Beškoski, V.. (2009). Novi proizvod i tehnologija za: „Formulacija pet mlečnih kašica ’Impamil-MIL MLEČNE KAŠICE’ bez glutenskih cerealija i uspostavljanje tehnologije za proizvodnju“ - Na tržištu!. 
University of Belgrade - Institute of Chemistry, Technology and Metallurgy..
https://hdl.handle.net/21.15107/rcub_cherry_5237
Vrvić M, Milić J, Martinov O, Ilić M, Lugonja N, Jakovljević D, Gojgić-Cvijović G, Potkonjak B, Spasić S, Miletić SB, Beškoski V. Novi proizvod i tehnologija za: „Formulacija pet mlečnih kašica ’Impamil-MIL MLEČNE KAŠICE’ bez glutenskih cerealija i uspostavljanje tehnologije za proizvodnju“ - Na tržištu!. 2009;.
https://hdl.handle.net/21.15107/rcub_cherry_5237 .
Vrvić, Miroslav, Milić, Jelena, Martinov, O., Ilić, Mila, Lugonja, Nikoleta, Jakovljević, Dragica, Gojgić-Cvijović, Gordana, Potkonjak, B., Spasić, Snežana, Miletić, Srđan B., Beškoski, Vladimir, "Novi proizvod i tehnologija za: „Formulacija pet mlečnih kašica ’Impamil-MIL MLEČNE KAŠICE’ bez glutenskih cerealija i uspostavljanje tehnologije za proizvodnju“ - Na tržištu!" (2009),
https://hdl.handle.net/21.15107/rcub_cherry_5237 .

Novi proizvod i tehnologija za: Specijalna mlečna formula bez laktoze, za ishranu odojčadi i male dece sa intolerancijom laktoze i dijarejom ’Impamil-MIL FL’“ - Na tržištu!

Vrvić, Miroslav; Milić, Jelena; Martinov, O.; Ilić, Mila; Lugonja, Nikoleta; Jakovljević, Dragica; Gojgić-Cvijović, Gordana; Potkonjak, B.; Spasić, Snežana; Miletić, Srđan B.; Beškoski, Vladimir

(University of Belgrade - Institute of Chemistry, Technology and Metallurgy, 2009)

TY  - GEN
AU  - Vrvić, Miroslav
AU  - Milić, Jelena
AU  - Martinov, O.
AU  - Ilić, Mila
AU  - Lugonja, Nikoleta
AU  - Jakovljević, Dragica
AU  - Gojgić-Cvijović, Gordana
AU  - Potkonjak, B.
AU  - Spasić, Snežana
AU  - Miletić, Srđan B.
AU  - Beškoski, Vladimir
PY  - 2009
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5238
AB  - Istraživanje, razvoj i primena rezultata u oblasti dizajniranja, formulisanja, osvajanja tehnologija i proizvodnja i plasman novih dijetetskih proizvoda-namirnica iz kategorija infant formula, prelaznih formula i hrane za decu do 3 godine, kao i specijalnih formulacija za posebne (medicinske) namene u uspešnoj, korektnoj, kolegijalnoj i tolerantnoj saradnji CH-IHTM i “Impamil” doo su dobar zalog za nove primene i stalna usavršavanja postojećih proizvoda prema savremenim rezultatima nauke o biohemiji hrane i ishrane i pedijatrije i zahtevima medjunarodne napredne regulative i legislative.
PB  - University of Belgrade - Institute of Chemistry, Technology and Metallurgy
T1  - Novi proizvod i tehnologija za: Specijalna mlečna formula bez laktoze, za ishranu odojčadi i male dece sa intolerancijom laktoze i dijarejom ’Impamil-MIL FL’“ - Na tržištu!
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5238
ER  - 
@misc{
author = "Vrvić, Miroslav and Milić, Jelena and Martinov, O. and Ilić, Mila and Lugonja, Nikoleta and Jakovljević, Dragica and Gojgić-Cvijović, Gordana and Potkonjak, B. and Spasić, Snežana and Miletić, Srđan B. and Beškoski, Vladimir",
year = "2009",
abstract = "Istraživanje, razvoj i primena rezultata u oblasti dizajniranja, formulisanja, osvajanja tehnologija i proizvodnja i plasman novih dijetetskih proizvoda-namirnica iz kategorija infant formula, prelaznih formula i hrane za decu do 3 godine, kao i specijalnih formulacija za posebne (medicinske) namene u uspešnoj, korektnoj, kolegijalnoj i tolerantnoj saradnji CH-IHTM i “Impamil” doo su dobar zalog za nove primene i stalna usavršavanja postojećih proizvoda prema savremenim rezultatima nauke o biohemiji hrane i ishrane i pedijatrije i zahtevima medjunarodne napredne regulative i legislative.",
publisher = "University of Belgrade - Institute of Chemistry, Technology and Metallurgy",
title = "Novi proizvod i tehnologija za: Specijalna mlečna formula bez laktoze, za ishranu odojčadi i male dece sa intolerancijom laktoze i dijarejom ’Impamil-MIL FL’“ - Na tržištu!",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5238"
}
Vrvić, M., Milić, J., Martinov, O., Ilić, M., Lugonja, N., Jakovljević, D., Gojgić-Cvijović, G., Potkonjak, B., Spasić, S., Miletić, S. B.,& Beškoski, V.. (2009). Novi proizvod i tehnologija za: Specijalna mlečna formula bez laktoze, za ishranu odojčadi i male dece sa intolerancijom laktoze i dijarejom ’Impamil-MIL FL’“ - Na tržištu!. 
University of Belgrade - Institute of Chemistry, Technology and Metallurgy..
https://hdl.handle.net/21.15107/rcub_cherry_5238
Vrvić M, Milić J, Martinov O, Ilić M, Lugonja N, Jakovljević D, Gojgić-Cvijović G, Potkonjak B, Spasić S, Miletić SB, Beškoski V. Novi proizvod i tehnologija za: Specijalna mlečna formula bez laktoze, za ishranu odojčadi i male dece sa intolerancijom laktoze i dijarejom ’Impamil-MIL FL’“ - Na tržištu!. 2009;.
https://hdl.handle.net/21.15107/rcub_cherry_5238 .
Vrvić, Miroslav, Milić, Jelena, Martinov, O., Ilić, Mila, Lugonja, Nikoleta, Jakovljević, Dragica, Gojgić-Cvijović, Gordana, Potkonjak, B., Spasić, Snežana, Miletić, Srđan B., Beškoski, Vladimir, "Novi proizvod i tehnologija za: Specijalna mlečna formula bez laktoze, za ishranu odojčadi i male dece sa intolerancijom laktoze i dijarejom ’Impamil-MIL FL’“ - Na tržištu!" (2009),
https://hdl.handle.net/21.15107/rcub_cherry_5238 .

Novi proizvod i tehnologija za: „Dopunska formula mleka za decu stariju od godinu dana - Impamil® MIL 3“, Proizvodjač „Impamil®“ doo, Beograd-Zemun Na tržištu!

Vrvić, Miroslav; Milić, Jelena; Martinov, Olga B.; Ilić, Mila; Lugonja, Nikoleta; Jakovljević, Dragica; Gojgić-Cvijović, Gordana; Potkonjak, Branislav; Spasić, Snežana; Miletić, Srđan B.; Beškoski, Vladimir

(University of Belgrade - Institute of Chemistry, Technology and Metallurgy, 2009)

TY  - GEN
AU  - Vrvić, Miroslav
AU  - Milić, Jelena
AU  - Martinov, Olga B.
AU  - Ilić, Mila
AU  - Lugonja, Nikoleta
AU  - Jakovljević, Dragica
AU  - Gojgić-Cvijović, Gordana
AU  - Potkonjak, Branislav
AU  - Spasić, Snežana
AU  - Miletić, Srđan B.
AU  - Beškoski, Vladimir
PY  - 2009
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5258
AB  - Istraživanje, razvoj i primena rezultata u oblasti dizajniranja, formulisanja, osvajanja tehnologija i proizvodnja i plasman novih dijetetskih proizvoda-namirnica iz kategorija infant formula, prelaznih formula i hrane za decu do 3 godine, kao i specijalnih formulacija za posebne (medicinske) namene u uspešnoj, korektnoj, kolegijalnoj i tolerantnoj saradnji CH-IHTM i “Impamil” doo su dobar zalog za nove primene i stalna usavršavanja postojećih proizvoda prema savremenim rezultatima nauke o biohemiji hrane i ishrane i pedijatrije i zahtevima medjunarodne napredne regulative i legislative.
PB  - University of Belgrade - Institute of Chemistry, Technology and Metallurgy
T1  - Novi proizvod i tehnologija za: „Dopunska formula mleka za decu stariju od godinu dana - Impamil® MIL 3“, Proizvodjač „Impamil®“ doo, Beograd-Zemun Na tržištu!
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5258
ER  - 
@misc{
author = "Vrvić, Miroslav and Milić, Jelena and Martinov, Olga B. and Ilić, Mila and Lugonja, Nikoleta and Jakovljević, Dragica and Gojgić-Cvijović, Gordana and Potkonjak, Branislav and Spasić, Snežana and Miletić, Srđan B. and Beškoski, Vladimir",
year = "2009",
abstract = "Istraživanje, razvoj i primena rezultata u oblasti dizajniranja, formulisanja, osvajanja tehnologija i proizvodnja i plasman novih dijetetskih proizvoda-namirnica iz kategorija infant formula, prelaznih formula i hrane za decu do 3 godine, kao i specijalnih formulacija za posebne (medicinske) namene u uspešnoj, korektnoj, kolegijalnoj i tolerantnoj saradnji CH-IHTM i “Impamil” doo su dobar zalog za nove primene i stalna usavršavanja postojećih proizvoda prema savremenim rezultatima nauke o biohemiji hrane i ishrane i pedijatrije i zahtevima medjunarodne napredne regulative i legislative.",
publisher = "University of Belgrade - Institute of Chemistry, Technology and Metallurgy",
title = "Novi proizvod i tehnologija za: „Dopunska formula mleka za decu stariju od godinu dana - Impamil® MIL 3“, Proizvodjač „Impamil®“ doo, Beograd-Zemun Na tržištu!",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5258"
}
Vrvić, M., Milić, J., Martinov, O. B., Ilić, M., Lugonja, N., Jakovljević, D., Gojgić-Cvijović, G., Potkonjak, B., Spasić, S., Miletić, S. B.,& Beškoski, V.. (2009). Novi proizvod i tehnologija za: „Dopunska formula mleka za decu stariju od godinu dana - Impamil® MIL 3“, Proizvodjač „Impamil®“ doo, Beograd-Zemun Na tržištu!. 
University of Belgrade - Institute of Chemistry, Technology and Metallurgy..
https://hdl.handle.net/21.15107/rcub_cherry_5258
Vrvić M, Milić J, Martinov OB, Ilić M, Lugonja N, Jakovljević D, Gojgić-Cvijović G, Potkonjak B, Spasić S, Miletić SB, Beškoski V. Novi proizvod i tehnologija za: „Dopunska formula mleka za decu stariju od godinu dana - Impamil® MIL 3“, Proizvodjač „Impamil®“ doo, Beograd-Zemun Na tržištu!. 2009;.
https://hdl.handle.net/21.15107/rcub_cherry_5258 .
Vrvić, Miroslav, Milić, Jelena, Martinov, Olga B., Ilić, Mila, Lugonja, Nikoleta, Jakovljević, Dragica, Gojgić-Cvijović, Gordana, Potkonjak, Branislav, Spasić, Snežana, Miletić, Srđan B., Beškoski, Vladimir, "Novi proizvod i tehnologija za: „Dopunska formula mleka za decu stariju od godinu dana - Impamil® MIL 3“, Proizvodjač „Impamil®“ doo, Beograd-Zemun Na tržištu!" (2009),
https://hdl.handle.net/21.15107/rcub_cherry_5258 .