TY  - RPRT
AU  - Božić, Tatjana T.
AU  - Beškoski, Vladimir
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6063
AB  - This report provides an overview of the recruitment procedure conducted for hiring additional personnel for the International Cooperation and Project Management Office at the University of Belgrade - Faculty of Chemistry within WP4 of PFAStwin project. The purpose of the recruitment process was to identify and select highly qualified candidates who possess the necessary skills and experience to contribute effectively to the office's operations and objectives.
T1  - D4.2 Report on the recruitment procedure for hiring  additional personnel for the GO of UBFC
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6063
ER  - 

@techreport{
author = "Božić, Tatjana T. and Beškoski, Vladimir",
year = "2023",
abstract = "This report provides an overview of the recruitment procedure conducted for hiring additional personnel for the International Cooperation and Project Management Office at the University of Belgrade - Faculty of Chemistry within WP4 of PFAStwin project. The purpose of the recruitment process was to identify and select highly qualified candidates who possess the necessary skills and experience to contribute effectively to the office's operations and objectives.",
title = "D4.2 Report on the recruitment procedure for hiring  additional personnel for the GO of UBFC",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6063"
}

Božić, T. T.,& Beškoski, V.. (2023). D4.2 Report on the recruitment procedure for hiring  additional personnel for the GO of UBFC. .
https://hdl.handle.net/21.15107/rcub_cherry_6063

Božić TT, Beškoski V. D4.2 Report on the recruitment procedure for hiring  additional personnel for the GO of UBFC. 2023;.
https://hdl.handle.net/21.15107/rcub_cherry_6063 .

Božić, Tatjana T., Beškoski, Vladimir, "D4.2 Report on the recruitment procedure for hiring  additional personnel for the GO of UBFC" (2023),
https://hdl.handle.net/21.15107/rcub_cherry_6063 .

TY  - RPRT
AU  - Božić, Tatjana T.
AU  - Gruden-Pavlović, Maja
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6062
AB  - Report with the action plan on the reorganization of the work force in the UBFC was developed within WP4 of the PFAStwin project. The aim is to devise a plan for better GO performance, which will be accepted by the governing body of the UBFC and put into force.
T1  - D4.1 Report with the Action plan on the reorganization of the work force in the UBFC
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6062
ER  - 

@techreport{
author = "Božić, Tatjana T. and Gruden-Pavlović, Maja",
year = "2023",
abstract = "Report with the action plan on the reorganization of the work force in the UBFC was developed within WP4 of the PFAStwin project. The aim is to devise a plan for better GO performance, which will be accepted by the governing body of the UBFC and put into force.",
title = "D4.1 Report with the Action plan on the reorganization of the work force in the UBFC",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6062"
}

Božić, T. T.,& Gruden-Pavlović, M.. (2023). D4.1 Report with the Action plan on the reorganization of the work force in the UBFC. .
https://hdl.handle.net/21.15107/rcub_cherry_6062

Božić TT, Gruden-Pavlović M. D4.1 Report with the Action plan on the reorganization of the work force in the UBFC. 2023;.
https://hdl.handle.net/21.15107/rcub_cherry_6062 .

Božić, Tatjana T., Gruden-Pavlović, Maja, "D4.1 Report with the Action plan on the reorganization of the work force in the UBFC" (2023),
https://hdl.handle.net/21.15107/rcub_cherry_6062 .

TY  - RPRT
AU  - Jiménez, Begoña
AU  - Beškoski, Vladimir
AU  - Božić, Tatjana T.
AU  - Colomer Vidal, Pere
AU  - Muñoz Arnanz, Juan
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6060
AB  - The development of the Scientific Strategy for PFAS Analysis and Bioremediation at 
UBFC has been successfully completed through Work Package 1 of the PFAStwin project. Under this strategy, a thorough ten-year plan has been formulated. The main goal of this plan is to 
establish UBFC as a leading hub of expertise in PFAS research, fostering creative projects and cooperative efforts to tackle PFAS-related challenges. The objective of this deliverable is to create an action plan outlining the essential measures required to achieve the goals set in the ten-year plan.
T1  - D1.3 Action plan
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6060
ER  - 

@techreport{
author = "Jiménez, Begoña and Beškoski, Vladimir and Božić, Tatjana T. and Colomer Vidal, Pere and Muñoz Arnanz, Juan",
year = "2023",
abstract = "The development of the Scientific Strategy for PFAS Analysis and Bioremediation at 
UBFC has been successfully completed through Work Package 1 of the PFAStwin project. Under this strategy, a thorough ten-year plan has been formulated. The main goal of this plan is to 
establish UBFC as a leading hub of expertise in PFAS research, fostering creative projects and cooperative efforts to tackle PFAS-related challenges. The objective of this deliverable is to create an action plan outlining the essential measures required to achieve the goals set in the ten-year plan.",
title = "D1.3 Action plan",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6060"
}

Jiménez, B., Beškoski, V., Božić, T. T., Colomer Vidal, P.,& Muñoz Arnanz, J.. (2023). D1.3 Action plan. .
https://hdl.handle.net/21.15107/rcub_cherry_6060

Jiménez B, Beškoski V, Božić TT, Colomer Vidal P, Muñoz Arnanz J. D1.3 Action plan. 2023;.
https://hdl.handle.net/21.15107/rcub_cherry_6060 .

Jiménez, Begoña, Beškoski, Vladimir, Božić, Tatjana T., Colomer Vidal, Pere, Muñoz Arnanz, Juan, "D1.3 Action plan" (2023),
https://hdl.handle.net/21.15107/rcub_cherry_6060 .

TY  - GEN
AU  - Beškoski, Vladimir
AU  - Lješević, Marija
AU  - Lončarević, Branka
AU  - Božić, Tatjana T.
AU  - Relić, Dubravka
AU  - Vujisić, Ljubodrag V.
AU  - Gruden-Pavlović, Maja
AU  - Lugonja, Nikoleta
AU  - Jiménez, Begoña
AU  - Colomer Vidal, Pere
AU  - Muñoz Arnanz, Juan
AU  - Battaglia, Fabienne
AU  - Crampon, Marc
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6048
AB  - Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals that have been widely used in various industrial and consumer products due to their unique properties, such as oil and water repellency, thermal stability, and durability. However, the persistence and mobility of these chemicals in the environment have raised concerns about their potential adverse effects on human health and the environment. PFAS have been detected on a global scale in various environmental media, such as soil, water, air, and biota. As a country undergoing economic development and transition, Serbia faces the challenge of managing and addressing the PFAS contamination in its environment. This challenge requires a comprehensive and science-based strategy that can effectively reduce the exposure and risks of PFAS to human health and the environment. This document aims to provide a scientific strategy for solving the PFAS challenge in Serbia. Firstly, it is important to acknowledge that PFAS are persistent and bioaccumulative in the environment, which means that they do not break down easily and can accumulate in the food chain, posing a long-term risk to human health and the environment. Therefore, a precautionary approach is necessary to minimize the exposure and risks of PFAS. International experience and cooperation are very important for developing an effective scientifc strategy for addressing the PFAS challenge in Serbia. PFAS are a global issue, and many countries have already implemented measures to manage and reduce the exposure and risks of PFAS. Therefore, it is important to draw on international experience and best practices when developing the strategy for Serbia. International experience can provide valuable insights into the sources, pathways, and fate of PFAS, as well as the e"ectiveness of various risk management measures. For example, the United States, Canada, and some European countries have established regulatory frameworks for PFAS, which can serve as a model for Serbia. Other countries have implemented remediation measures for contaminated sites, which can provide valuable insights for selecting appropriate remediation technologies in Serbia. Moreover, international experience can provide access to the latest scientific knowledge, methods, and technologies for assessing and managing PFAS contamination. For example, international organizations such as the United Nations Environment Programme (UNEP) and the Organization for Economic Co-operation and Development (OECD) have developed guidance documents and tools for assessing and managing PFAS contamination. The scientific strategy for solving the PFAS challenge in Serbia is based on a thorough understanding of the sources, pathways, and fate of PFAS in the environment. It is also based on a comprehensive and systematic approach, including risk assessment, monitoring, regulation, remediation, and communication. This strategy is tailored to the specific context and needs of Serbia. It is based on the latest scientifc knowledge and practical experience from other countries and regions, focusing on the European Union, USA, China and Japan. The cultural, social, economic, and political factors can affect the implementation and effectiveness of the strategy, and therefore, the strategy is developed through a collaborative and participatory process involving stakeholders from different sectors and levels. The international experience provided helpful guidance and lessons learned, but ultimately, the strategy is based on local knowledge, priorities, and capacities. By implementing this strategy, we aim to contribute to that Serbia can protect its citizens and environment from the potential harm of PFAS and achieve sustainable development.
PB  - University of Belgrade – Faculty of Chemistry
T1  - Scientifc Strategy for PFAS Analysis and Bioremediation at UBFC  (2023-2033)
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6048
ER  - 

@misc{
author = "Beškoski, Vladimir and Lješević, Marija and Lončarević, Branka and Božić, Tatjana T. and Relić, Dubravka and Vujisić, Ljubodrag V. and Gruden-Pavlović, Maja and Lugonja, Nikoleta and Jiménez, Begoña and Colomer Vidal, Pere and Muñoz Arnanz, Juan and Battaglia, Fabienne and Crampon, Marc",
year = "2023",
abstract = "Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals that have been widely used in various industrial and consumer products due to their unique properties, such as oil and water repellency, thermal stability, and durability. However, the persistence and mobility of these chemicals in the environment have raised concerns about their potential adverse effects on human health and the environment. PFAS have been detected on a global scale in various environmental media, such as soil, water, air, and biota. As a country undergoing economic development and transition, Serbia faces the challenge of managing and addressing the PFAS contamination in its environment. This challenge requires a comprehensive and science-based strategy that can effectively reduce the exposure and risks of PFAS to human health and the environment. This document aims to provide a scientific strategy for solving the PFAS challenge in Serbia. Firstly, it is important to acknowledge that PFAS are persistent and bioaccumulative in the environment, which means that they do not break down easily and can accumulate in the food chain, posing a long-term risk to human health and the environment. Therefore, a precautionary approach is necessary to minimize the exposure and risks of PFAS. International experience and cooperation are very important for developing an effective scientifc strategy for addressing the PFAS challenge in Serbia. PFAS are a global issue, and many countries have already implemented measures to manage and reduce the exposure and risks of PFAS. Therefore, it is important to draw on international experience and best practices when developing the strategy for Serbia. International experience can provide valuable insights into the sources, pathways, and fate of PFAS, as well as the e"ectiveness of various risk management measures. For example, the United States, Canada, and some European countries have established regulatory frameworks for PFAS, which can serve as a model for Serbia. Other countries have implemented remediation measures for contaminated sites, which can provide valuable insights for selecting appropriate remediation technologies in Serbia. Moreover, international experience can provide access to the latest scientific knowledge, methods, and technologies for assessing and managing PFAS contamination. For example, international organizations such as the United Nations Environment Programme (UNEP) and the Organization for Economic Co-operation and Development (OECD) have developed guidance documents and tools for assessing and managing PFAS contamination. The scientific strategy for solving the PFAS challenge in Serbia is based on a thorough understanding of the sources, pathways, and fate of PFAS in the environment. It is also based on a comprehensive and systematic approach, including risk assessment, monitoring, regulation, remediation, and communication. This strategy is tailored to the specific context and needs of Serbia. It is based on the latest scientifc knowledge and practical experience from other countries and regions, focusing on the European Union, USA, China and Japan. The cultural, social, economic, and political factors can affect the implementation and effectiveness of the strategy, and therefore, the strategy is developed through a collaborative and participatory process involving stakeholders from different sectors and levels. The international experience provided helpful guidance and lessons learned, but ultimately, the strategy is based on local knowledge, priorities, and capacities. By implementing this strategy, we aim to contribute to that Serbia can protect its citizens and environment from the potential harm of PFAS and achieve sustainable development.",
publisher = "University of Belgrade – Faculty of Chemistry",
title = "Scientifc Strategy for PFAS Analysis and Bioremediation at UBFC  (2023-2033)",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6048"
}

Beškoski, V., Lješević, M., Lončarević, B., Božić, T. T., Relić, D., Vujisić, L. V., Gruden-Pavlović, M., Lugonja, N., Jiménez, B., Colomer Vidal, P., Muñoz Arnanz, J., Battaglia, F.,& Crampon, M.. (2023). Scientifc Strategy for PFAS Analysis and Bioremediation at UBFC  (2023-2033). 
University of Belgrade – Faculty of Chemistry..
https://hdl.handle.net/21.15107/rcub_cherry_6048

Beškoski V, Lješević M, Lončarević B, Božić TT, Relić D, Vujisić LV, Gruden-Pavlović M, Lugonja N, Jiménez B, Colomer Vidal P, Muñoz Arnanz J, Battaglia F, Crampon M. Scientifc Strategy for PFAS Analysis and Bioremediation at UBFC  (2023-2033). 2023;.
https://hdl.handle.net/21.15107/rcub_cherry_6048 .

Beškoski, Vladimir, Lješević, Marija, Lončarević, Branka, Božić, Tatjana T., Relić, Dubravka, Vujisić, Ljubodrag V., Gruden-Pavlović, Maja, Lugonja, Nikoleta, Jiménez, Begoña, Colomer Vidal, Pere, Muñoz Arnanz, Juan, Battaglia, Fabienne, Crampon, Marc, "Scientifc Strategy for PFAS Analysis and Bioremediation at UBFC  (2023-2033)" (2023),
https://hdl.handle.net/21.15107/rcub_cherry_6048 .

TY  - RPRT
AU  - Jiménez, Begoña
AU  - Beškoski, Vladimir
AU  - Božić, Tatjana T.
AU  - Colomer Vidal, Pere
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6061
AB  - The current state analysis report of the Development of scientific strategy for PFAS analysis and remediation for UBFC has been developed within WP1 of the PFAStwin project. This report describes 
all the activities involved in the development of the current state analysis, which will be an integral part of scientific strategy developed within WP1.
T1  - D1.1 Current state analysis report
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6061
ER  - 

@techreport{
author = "Jiménez, Begoña and Beškoski, Vladimir and Božić, Tatjana T. and Colomer Vidal, Pere",
year = "2022",
abstract = "The current state analysis report of the Development of scientific strategy for PFAS analysis and remediation for UBFC has been developed within WP1 of the PFAStwin project. This report describes 
all the activities involved in the development of the current state analysis, which will be an integral part of scientific strategy developed within WP1.",
title = "D1.1 Current state analysis report",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6061"
}

Jiménez, B., Beškoski, V., Božić, T. T.,& Colomer Vidal, P.. (2022). D1.1 Current state analysis report. .
https://hdl.handle.net/21.15107/rcub_cherry_6061

Jiménez B, Beškoski V, Božić TT, Colomer Vidal P. D1.1 Current state analysis report. 2022;.
https://hdl.handle.net/21.15107/rcub_cherry_6061 .

Jiménez, Begoña, Beškoski, Vladimir, Božić, Tatjana T., Colomer Vidal, Pere, "D1.1 Current state analysis report" (2022),
https://hdl.handle.net/21.15107/rcub_cherry_6061 .

TY  - RPRT
AU  - Beškoski, Vladimir
AU  - Božić, Tatjana T.
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6047
AB  - A report on the kick-off meeting has been developed within Work Package 6 
Management of the PFAStwin. This report describes the first consortium meeting and 
all the decisions made to achieve the PFAStwin project's goals through effective 
management and networking.
T1  - D6.1. Report on kick-off meeting
UR  - https://hdl.handle.net/21.15107/rcub_cherry_6047
ER  - 

@techreport{
author = "Beškoski, Vladimir and Božić, Tatjana T.",
year = "2022",
abstract = "A report on the kick-off meeting has been developed within Work Package 6 
Management of the PFAStwin. This report describes the first consortium meeting and 
all the decisions made to achieve the PFAStwin project's goals through effective 
management and networking.",
title = "D6.1. Report on kick-off meeting",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6047"
}

Beškoski, V.,& Božić, T. T.. (2022). D6.1. Report on kick-off meeting. .
https://hdl.handle.net/21.15107/rcub_cherry_6047

Beškoski V, Božić TT. D6.1. Report on kick-off meeting. 2022;.
https://hdl.handle.net/21.15107/rcub_cherry_6047 .

Beškoski, Vladimir, Božić, Tatjana T., "D6.1. Report on kick-off meeting" (2022),
https://hdl.handle.net/21.15107/rcub_cherry_6047 .

TY  - JOUR
AU  - Kovacevic-Filipovic, Milica
AU  - Ilić, Vesna
AU  - Vujčić, Zoran
AU  - Dojnov, Biljana
AU  - Stevanov-Pavlović, Marija
AU  - Mijacevic, Zora
AU  - Božić, Tatjana T.
PY  - 2012
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1257
AB  - Serum amyloid A proteins (SAA) are very sensitive acute phase proteins, displaying multiple isoforms in plasma and different body fluids. They are currently under investigation as biomarkers of diseases. The aim of the present study was to compare the concentration and isoform expression of SAA in serum and milk of cows with bacteriologically negative milk (control group) and naturally occurring Staphylococcus aureus (S. aureus) subclinical mastitis (subclinical mastitis group). Somatic cell count (SCC) and bacteriological analyses were performed to establish the control and subclinical mastitis group. SAA concentration was evaluated using a commercial ELISA kit, while expression of different isoforms (serum A-SAA and milk M-SAA3 isoforms) was visualized by denaturing isoelectrical focusing and immunoblotting. The SAA concentrations in sera and milk of cows in the subclinical mastitis group were three and 100 times higher than in those from the control group of cows, respectively. Cows in the subclinical mastitis group had more acidic SAA isoforms in serum with the most prominent one at pI 5.5. This isoform was not detected in sera from the control group. Milk samples in the subclinical mastitis group contained abundant highly alkaline M-SAA3 isoforms and most of the serum isoforms, except for that at pI 5.5. In the subclinical mastitis group SAA isoforms with equivalent pI as serum isoforms accounted for 20% of the total SAA concentration in milk. There were significant differences in the concentrations and isoform patterns of SAA in serum and milk between the control and subclinical mastitis groups of cows. Also, we demonstrated that serum SAA isoforms were not transferred to milk proportion to their plasma content. (C) 2011 Elsevier B.V. All rights reserved.
PB  - Elsevier Science Bv, Amsterdam
T2  - Veterinary Immunology and Immunopathology
T1  - Serum amyloid A isoforms in serum and milk from cows with Staphylococcus aureus subclinical mastitis
VL  - 145
IS  - 1-2
SP  - 120
EP  - 128
DO  - 10.1016/j.vetimm.2011.10.015
ER  - 

@article{
author = "Kovacevic-Filipovic, Milica and Ilić, Vesna and Vujčić, Zoran and Dojnov, Biljana and Stevanov-Pavlović, Marija and Mijacevic, Zora and Božić, Tatjana T.",
year = "2012",
abstract = "Serum amyloid A proteins (SAA) are very sensitive acute phase proteins, displaying multiple isoforms in plasma and different body fluids. They are currently under investigation as biomarkers of diseases. The aim of the present study was to compare the concentration and isoform expression of SAA in serum and milk of cows with bacteriologically negative milk (control group) and naturally occurring Staphylococcus aureus (S. aureus) subclinical mastitis (subclinical mastitis group). Somatic cell count (SCC) and bacteriological analyses were performed to establish the control and subclinical mastitis group. SAA concentration was evaluated using a commercial ELISA kit, while expression of different isoforms (serum A-SAA and milk M-SAA3 isoforms) was visualized by denaturing isoelectrical focusing and immunoblotting. The SAA concentrations in sera and milk of cows in the subclinical mastitis group were three and 100 times higher than in those from the control group of cows, respectively. Cows in the subclinical mastitis group had more acidic SAA isoforms in serum with the most prominent one at pI 5.5. This isoform was not detected in sera from the control group. Milk samples in the subclinical mastitis group contained abundant highly alkaline M-SAA3 isoforms and most of the serum isoforms, except for that at pI 5.5. In the subclinical mastitis group SAA isoforms with equivalent pI as serum isoforms accounted for 20% of the total SAA concentration in milk. There were significant differences in the concentrations and isoform patterns of SAA in serum and milk between the control and subclinical mastitis groups of cows. Also, we demonstrated that serum SAA isoforms were not transferred to milk proportion to their plasma content. (C) 2011 Elsevier B.V. All rights reserved.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Veterinary Immunology and Immunopathology",
title = "Serum amyloid A isoforms in serum and milk from cows with Staphylococcus aureus subclinical mastitis",
volume = "145",
number = "1-2",
pages = "120-128",
doi = "10.1016/j.vetimm.2011.10.015"
}

Kovacevic-Filipovic, M., Ilić, V., Vujčić, Z., Dojnov, B., Stevanov-Pavlović, M., Mijacevic, Z.,& Božić, T. T.. (2012). Serum amyloid A isoforms in serum and milk from cows with Staphylococcus aureus subclinical mastitis. in Veterinary Immunology and Immunopathology
Elsevier Science Bv, Amsterdam., 145(1-2), 120-128.
https://doi.org/10.1016/j.vetimm.2011.10.015

Kovacevic-Filipovic M, Ilić V, Vujčić Z, Dojnov B, Stevanov-Pavlović M, Mijacevic Z, Božić TT. Serum amyloid A isoforms in serum and milk from cows with Staphylococcus aureus subclinical mastitis. in Veterinary Immunology and Immunopathology. 2012;145(1-2):120-128.
doi:10.1016/j.vetimm.2011.10.015 .

Kovacevic-Filipovic, Milica, Ilić, Vesna, Vujčić, Zoran, Dojnov, Biljana, Stevanov-Pavlović, Marija, Mijacevic, Zora, Božić, Tatjana T., "Serum amyloid A isoforms in serum and milk from cows with Staphylococcus aureus subclinical mastitis" in Veterinary Immunology and Immunopathology, 145, no. 1-2 (2012):120-128,
https://doi.org/10.1016/j.vetimm.2011.10.015 . .

TY  - JOUR
AU  - Milenković, Milica R.
AU  - Warżajtis, Beata
AU  - Rychlewska, Urszula
AU  - Radanović, Dušanka D.
AU  - Anđelković, Katarina K.
AU  - Božić, Tatjana T.
AU  - Vujčić, Miroslava
AU  - Sladić, Dušan
PY  - 2012
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1267
AB  - The facile preparation of a racemic hydrazine bridged diphosphonium compound possessing a ring system analogous to bicyclo[3.3.2]decane is reported. Although the reaction yield is low, the structure of the compound, which possesses an eight-membered ring, two phosphonium cationic centers, a biimino bridge, molecular chirality and two fused aromatic rings locked into roughly perpendicular planes is unusual. The compound displays substantial biological activity in the brine shrimp test and cleaves plasmid DNA.
PB  - Mdpi Ag, Basel
T2  - Molecules
T1  - Synthesis, Spectral and Solid State Characterization of a New Bioactive Hydrazine Bridged Cyclic Diphosphonium Compound
VL  - 17
IS  - 3
SP  - 2567
EP  - 2578
DO  - 10.3390/molecules17032567
ER  - 

@article{
author = "Milenković, Milica R. and Warżajtis, Beata and Rychlewska, Urszula and Radanović, Dušanka D. and Anđelković, Katarina K. and Božić, Tatjana T. and Vujčić, Miroslava and Sladić, Dušan",
year = "2012",
abstract = "The facile preparation of a racemic hydrazine bridged diphosphonium compound possessing a ring system analogous to bicyclo[3.3.2]decane is reported. Although the reaction yield is low, the structure of the compound, which possesses an eight-membered ring, two phosphonium cationic centers, a biimino bridge, molecular chirality and two fused aromatic rings locked into roughly perpendicular planes is unusual. The compound displays substantial biological activity in the brine shrimp test and cleaves plasmid DNA.",
publisher = "Mdpi Ag, Basel",
journal = "Molecules",
title = "Synthesis, Spectral and Solid State Characterization of a New Bioactive Hydrazine Bridged Cyclic Diphosphonium Compound",
volume = "17",
number = "3",
pages = "2567-2578",
doi = "10.3390/molecules17032567"
}

Milenković, M. R., Warżajtis, B., Rychlewska, U., Radanović, D. D., Anđelković, K. K., Božić, T. T., Vujčić, M.,& Sladić, D.. (2012). Synthesis, Spectral and Solid State Characterization of a New Bioactive Hydrazine Bridged Cyclic Diphosphonium Compound. in Molecules
Mdpi Ag, Basel., 17(3), 2567-2578.
https://doi.org/10.3390/molecules17032567

Milenković MR, Warżajtis B, Rychlewska U, Radanović DD, Anđelković KK, Božić TT, Vujčić M, Sladić D. Synthesis, Spectral and Solid State Characterization of a New Bioactive Hydrazine Bridged Cyclic Diphosphonium Compound. in Molecules. 2012;17(3):2567-2578.
doi:10.3390/molecules17032567 .

Milenković, Milica R., Warżajtis, Beata, Rychlewska, Urszula, Radanović, Dušanka D., Anđelković, Katarina K., Božić, Tatjana T., Vujčić, Miroslava, Sladić, Dušan, "Synthesis, Spectral and Solid State Characterization of a New Bioactive Hydrazine Bridged Cyclic Diphosphonium Compound" in Molecules, 17, no. 3 (2012):2567-2578,
https://doi.org/10.3390/molecules17032567 . .

TY  - JOUR
AU  - Božić, Tatjana T.
AU  - Novaković, Irena T.
AU  - Gasic, Miroslav J.
AU  - Juranić, Zorica D.
AU  - Stanojković, Tatjana
AU  - Tufegdžić, Srđan
AU  - Kljajić, Zoran
AU  - Sladić, Dušan
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1057
AB  - Nine alkyl(aryl)thio derivatives of the marine sesquiterpene quinone avarone were synthesized by nucleophilic addition of thiols or thiophenol to avarone. In most cases only one regioisomer was obtained. Their cytotoxic activities, brine shrimp lethality and antibacterial activity were evaluated, as well as those of some previously synthesized avarone derivatives. Anti-HIV activity of two derivatives was tested. Electrochemical properties were determined for all the derivatives in Order to obtain more accurate information on structure-activity relationships. Most derivatives showed cytotoxic activity against tumor cell lines, with IC(50) values less than 10 mu M for some of them, in particular those with electron-donating substituents. The most active Compound was 4'-(methylamino)avarone, with IC(50) value of 2.4 mu M to melanoma Fem-X cells, and no cytotoxicity to normal lymphocytes. (C) 2009 Elsevier Masson SAS. All Fights reserved.
PB  - Elsevier France-Editions Scientifiques Medicales Elsevier, Paris
T2  - European Journal of Medicinal Chemistry
T1  - Synthesis and biological activity of derivatives of the marine quinone avarone
VL  - 45
IS  - 3
SP  - 923
EP  - 929
DO  - 10.1016/j.ejmech.2009.11.033
ER  - 

@article{
author = "Božić, Tatjana T. and Novaković, Irena T. and Gasic, Miroslav J. and Juranić, Zorica D. and Stanojković, Tatjana and Tufegdžić, Srđan and Kljajić, Zoran and Sladić, Dušan",
year = "2010",
abstract = "Nine alkyl(aryl)thio derivatives of the marine sesquiterpene quinone avarone were synthesized by nucleophilic addition of thiols or thiophenol to avarone. In most cases only one regioisomer was obtained. Their cytotoxic activities, brine shrimp lethality and antibacterial activity were evaluated, as well as those of some previously synthesized avarone derivatives. Anti-HIV activity of two derivatives was tested. Electrochemical properties were determined for all the derivatives in Order to obtain more accurate information on structure-activity relationships. Most derivatives showed cytotoxic activity against tumor cell lines, with IC(50) values less than 10 mu M for some of them, in particular those with electron-donating substituents. The most active Compound was 4'-(methylamino)avarone, with IC(50) value of 2.4 mu M to melanoma Fem-X cells, and no cytotoxicity to normal lymphocytes. (C) 2009 Elsevier Masson SAS. All Fights reserved.",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Paris",
journal = "European Journal of Medicinal Chemistry",
title = "Synthesis and biological activity of derivatives of the marine quinone avarone",
volume = "45",
number = "3",
pages = "923-929",
doi = "10.1016/j.ejmech.2009.11.033"
}

Božić, T. T., Novaković, I. T., Gasic, M. J., Juranić, Z. D., Stanojković, T., Tufegdžić, S., Kljajić, Z.,& Sladić, D.. (2010). Synthesis and biological activity of derivatives of the marine quinone avarone. in European Journal of Medicinal Chemistry
Elsevier France-Editions Scientifiques Medicales Elsevier, Paris., 45(3), 923-929.
https://doi.org/10.1016/j.ejmech.2009.11.033

Božić TT, Novaković IT, Gasic MJ, Juranić ZD, Stanojković T, Tufegdžić S, Kljajić Z, Sladić D. Synthesis and biological activity of derivatives of the marine quinone avarone. in European Journal of Medicinal Chemistry. 2010;45(3):923-929.
doi:10.1016/j.ejmech.2009.11.033 .

Božić, Tatjana T., Novaković, Irena T., Gasic, Miroslav J., Juranić, Zorica D., Stanojković, Tatjana, Tufegdžić, Srđan, Kljajić, Zoran, Sladić, Dušan, "Synthesis and biological activity of derivatives of the marine quinone avarone" in European Journal of Medicinal Chemistry, 45, no. 3 (2010):923-929,
https://doi.org/10.1016/j.ejmech.2009.11.033 . .

TY  - JOUR
AU  - Todorović, Tamara
AU  - Bacchi, Alessia
AU  - Sladić, Dušan
AU  - Todorović, Nina
AU  - Božić, Tatjana T.
AU  - Radanović, Dušanka D.
AU  - Filipović, Nenad R.
AU  - Pelizzi, Giancarlo
AU  - Anđelković, Katarina K.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/873
AB  - Five new complexes of Pt(II), Pd(II), Co(III) and Ni(II) with 2-pyridine(quinoline) carboxaldehyde selenose-micarbazones were synthesized and characterized. Crystal structures of Pt(II) complex with the pyridine derivative and Co(III) complex with the quinoline derivative were determined. In all complexes the ligands were coordinated through N(2)Se donor atom set forming either square-planar (Pt, Pd) or octahedral (Co, Ni) geometry. All complexes showed biological activity. (C) 2009 Elsevier B. V. All rights reserved.
PB  - Elsevier Science Sa, Lausanne
T2  - Inorganica Chimica Acta
T1  - Synthesis, characterization and biological activity evaluation of Pt(II), Pd(II), Co(III) and Ni(II) complexes with N-heteroaromatic selenosemicarbazones
VL  - 362
IS  - 10
SP  - 3813
EP  - 3820
DO  - 10.1016/j.ica.2009.04.047
ER  - 

@article{
author = "Todorović, Tamara and Bacchi, Alessia and Sladić, Dušan and Todorović, Nina and Božić, Tatjana T. and Radanović, Dušanka D. and Filipović, Nenad R. and Pelizzi, Giancarlo and Anđelković, Katarina K.",
year = "2009",
abstract = "Five new complexes of Pt(II), Pd(II), Co(III) and Ni(II) with 2-pyridine(quinoline) carboxaldehyde selenose-micarbazones were synthesized and characterized. Crystal structures of Pt(II) complex with the pyridine derivative and Co(III) complex with the quinoline derivative were determined. In all complexes the ligands were coordinated through N(2)Se donor atom set forming either square-planar (Pt, Pd) or octahedral (Co, Ni) geometry. All complexes showed biological activity. (C) 2009 Elsevier B. V. All rights reserved.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Inorganica Chimica Acta",
title = "Synthesis, characterization and biological activity evaluation of Pt(II), Pd(II), Co(III) and Ni(II) complexes with N-heteroaromatic selenosemicarbazones",
volume = "362",
number = "10",
pages = "3813-3820",
doi = "10.1016/j.ica.2009.04.047"
}

Todorović, T., Bacchi, A., Sladić, D., Todorović, N., Božić, T. T., Radanović, D. D., Filipović, N. R., Pelizzi, G.,& Anđelković, K. K.. (2009). Synthesis, characterization and biological activity evaluation of Pt(II), Pd(II), Co(III) and Ni(II) complexes with N-heteroaromatic selenosemicarbazones. in Inorganica Chimica Acta
Elsevier Science Sa, Lausanne., 362(10), 3813-3820.
https://doi.org/10.1016/j.ica.2009.04.047

Todorović T, Bacchi A, Sladić D, Todorović N, Božić TT, Radanović DD, Filipović NR, Pelizzi G, Anđelković KK. Synthesis, characterization and biological activity evaluation of Pt(II), Pd(II), Co(III) and Ni(II) complexes with N-heteroaromatic selenosemicarbazones. in Inorganica Chimica Acta. 2009;362(10):3813-3820.
doi:10.1016/j.ica.2009.04.047 .

Todorović, Tamara, Bacchi, Alessia, Sladić, Dušan, Todorović, Nina, Božić, Tatjana T., Radanović, Dušanka D., Filipović, Nenad R., Pelizzi, Giancarlo, Anđelković, Katarina K., "Synthesis, characterization and biological activity evaluation of Pt(II), Pd(II), Co(III) and Ni(II) complexes with N-heteroaromatic selenosemicarbazones" in Inorganica Chimica Acta, 362, no. 10 (2009):3813-3820,
https://doi.org/10.1016/j.ica.2009.04.047 . .

TY  - JOUR
AU  - Gasi, Katarina M. Penov
AU  - Brenesel, Maja Dj. Djurendic
AU  - Djurendic, Evgenija A.
AU  - Sakac, Marija N.
AU  - Canadi, Janos J.
AU  - Daljev, Jovana J.
AU  - Armbruster, Thomas
AU  - Andrić, Silvana A.
AU  - Sladić, Dušan
AU  - Božić, Tatjana T.
AU  - Novaković, Irena T.
AU  - Juranić, Zorica D.
PY  - 2007
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/765
AB  - Starting from dehydroepiandrosterone (1) 17-picolyl (2), 17-picolinylidene (7), 17-picolinylidene-16-one (10 and 11), and 17-picolyl-16-one (15) derivatives of androst-5-ene were synthesized in one, two, four and five steps respectively. By the Oppenauer oxidation or dehydration of 2, 7, 10, and 11 with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ), the corresponding A and B ring modified derivatives 3, 5, 6, 8, 9, and 12-14 were obtained. The structure of 2 was unambiguously proved by the appropriate X-ray structural analysis. Compounds 3, 5,9,12-14 showed inhibitory activity against the enzyme aromatase. Antibacterial activity toxicity to brine shrimp Artemia salina, antitumor activity against three tumor cell lines (human cervix carcinoma HeLa cells, human melanoma FemX cells, and human myelogenous leukemia K562 cells) and toxicity against peripheral blood mononuclear cells were evaluated. Three tested compounds, namely 11, 13, and 15, showed strong activity against all three cell lines, the IC50 values being in the range of 4-10 mu M. (c) 2006 Elsevier Inc. All rights reserved.
PB  - Elsevier Science Inc, New York
T2  - Steroids
T1  - Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives
VL  - 72
IS  - 1
SP  - 31
EP  - 40
DO  - 10.1016/j.steroids.2006.10.002
ER  - 

@article{
author = "Gasi, Katarina M. Penov and Brenesel, Maja Dj. Djurendic and Djurendic, Evgenija A. and Sakac, Marija N. and Canadi, Janos J. and Daljev, Jovana J. and Armbruster, Thomas and Andrić, Silvana A. and Sladić, Dušan and Božić, Tatjana T. and Novaković, Irena T. and Juranić, Zorica D.",
year = "2007",
abstract = "Starting from dehydroepiandrosterone (1) 17-picolyl (2), 17-picolinylidene (7), 17-picolinylidene-16-one (10 and 11), and 17-picolyl-16-one (15) derivatives of androst-5-ene were synthesized in one, two, four and five steps respectively. By the Oppenauer oxidation or dehydration of 2, 7, 10, and 11 with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ), the corresponding A and B ring modified derivatives 3, 5, 6, 8, 9, and 12-14 were obtained. The structure of 2 was unambiguously proved by the appropriate X-ray structural analysis. Compounds 3, 5,9,12-14 showed inhibitory activity against the enzyme aromatase. Antibacterial activity toxicity to brine shrimp Artemia salina, antitumor activity against three tumor cell lines (human cervix carcinoma HeLa cells, human melanoma FemX cells, and human myelogenous leukemia K562 cells) and toxicity against peripheral blood mononuclear cells were evaluated. Three tested compounds, namely 11, 13, and 15, showed strong activity against all three cell lines, the IC50 values being in the range of 4-10 mu M. (c) 2006 Elsevier Inc. All rights reserved.",
publisher = "Elsevier Science Inc, New York",
journal = "Steroids",
title = "Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives",
volume = "72",
number = "1",
pages = "31-40",
doi = "10.1016/j.steroids.2006.10.002"
}

Gasi, K. M. P., Brenesel, M. Dj. D., Djurendic, E. A., Sakac, M. N., Canadi, J. J., Daljev, J. J., Armbruster, T., Andrić, S. A., Sladić, D., Božić, T. T., Novaković, I. T.,& Juranić, Z. D.. (2007). Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives. in Steroids
Elsevier Science Inc, New York., 72(1), 31-40.
https://doi.org/10.1016/j.steroids.2006.10.002

Gasi KMP, Brenesel MDD, Djurendic EA, Sakac MN, Canadi JJ, Daljev JJ, Armbruster T, Andrić SA, Sladić D, Božić TT, Novaković IT, Juranić ZD. Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives. in Steroids. 2007;72(1):31-40.
doi:10.1016/j.steroids.2006.10.002 .

Gasi, Katarina M. Penov, Brenesel, Maja Dj. Djurendic, Djurendic, Evgenija A., Sakac, Marija N., Canadi, Janos J., Daljev, Jovana J., Armbruster, Thomas, Andrić, Silvana A., Sladić, Dušan, Božić, Tatjana T., Novaković, Irena T., Juranić, Zorica D., "Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives" in Steroids, 72, no. 1 (2007):31-40,
https://doi.org/10.1016/j.steroids.2006.10.002 . .

TY  - JOUR
AU  - Todorović, Tamara
AU  - Bacchi, Alessia
AU  - Juranic, Nenad O.
AU  - Sladić, Dušan
AU  - Pelizzi, Giancarlo
AU  - Božić, Tatjana T.
AU  - Filipović, Nenad R.
AU  - Anđelković, Katarina K.
PY  - 2007
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/859
AB  - New complexes of Cd(II), Zn(II) and Ni(II) with 2-quinolinecarboxaldehyde selenosernicarbazone (Hqasesc) were synthesized and structurally characterized. The structure of the ligand, Cd(II) and Zn(II) complexes was determined by NMR and IR spectroscopy, elemental microanalysis and molar conductivity measurements. Both complexes occur in solution in two forms, the major tetrahedral and minor octahedral. In the major Cd(II) complex one qasesc(-) ligand is coordinated as a tridentate, the fourth coordination site being occupied by acetate, while in the major Zn(II) complex two qasesc- ligands are coordinated as bidentates. In both minor complexes two qasesc- ligands are coordinated as tridentates forming the octahedral geometry around the central metal ion. The only paramagnetic complex in the series is Ni(II) complex for which X-ray structure analysis was performed. The complex has the angularly distorted octahedral geometry with two qasesc- ligands coordinated as tridentates, in a similar way as in the minor complexes of Cd(11) and Zn(11). (c) 2007 Elsevier Ltd. All rights reserved.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Polyhedron
T1  - Synthesis and characterization of novel Cd(II), Zn(II) and Ni(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone. Crystal structure of bis(2-quinolinecarboxaldehyde selenosemicarbazonato)nickel(II)
VL  - 26
IS  - 13
SP  - 3428
EP  - 3436
DO  - 10.1016/j.poly.2007.03.023
ER  - 

@article{
author = "Todorović, Tamara and Bacchi, Alessia and Juranic, Nenad O. and Sladić, Dušan and Pelizzi, Giancarlo and Božić, Tatjana T. and Filipović, Nenad R. and Anđelković, Katarina K.",
year = "2007",
abstract = "New complexes of Cd(II), Zn(II) and Ni(II) with 2-quinolinecarboxaldehyde selenosernicarbazone (Hqasesc) were synthesized and structurally characterized. The structure of the ligand, Cd(II) and Zn(II) complexes was determined by NMR and IR spectroscopy, elemental microanalysis and molar conductivity measurements. Both complexes occur in solution in two forms, the major tetrahedral and minor octahedral. In the major Cd(II) complex one qasesc(-) ligand is coordinated as a tridentate, the fourth coordination site being occupied by acetate, while in the major Zn(II) complex two qasesc- ligands are coordinated as bidentates. In both minor complexes two qasesc- ligands are coordinated as tridentates forming the octahedral geometry around the central metal ion. The only paramagnetic complex in the series is Ni(II) complex for which X-ray structure analysis was performed. The complex has the angularly distorted octahedral geometry with two qasesc- ligands coordinated as tridentates, in a similar way as in the minor complexes of Cd(11) and Zn(11). (c) 2007 Elsevier Ltd. All rights reserved.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Polyhedron",
title = "Synthesis and characterization of novel Cd(II), Zn(II) and Ni(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone. Crystal structure of bis(2-quinolinecarboxaldehyde selenosemicarbazonato)nickel(II)",
volume = "26",
number = "13",
pages = "3428-3436",
doi = "10.1016/j.poly.2007.03.023"
}

Todorović, T., Bacchi, A., Juranic, N. O., Sladić, D., Pelizzi, G., Božić, T. T., Filipović, N. R.,& Anđelković, K. K.. (2007). Synthesis and characterization of novel Cd(II), Zn(II) and Ni(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone. Crystal structure of bis(2-quinolinecarboxaldehyde selenosemicarbazonato)nickel(II). in Polyhedron
Pergamon-Elsevier Science Ltd, Oxford., 26(13), 3428-3436.
https://doi.org/10.1016/j.poly.2007.03.023

Todorović T, Bacchi A, Juranic NO, Sladić D, Pelizzi G, Božić TT, Filipović NR, Anđelković KK. Synthesis and characterization of novel Cd(II), Zn(II) and Ni(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone. Crystal structure of bis(2-quinolinecarboxaldehyde selenosemicarbazonato)nickel(II). in Polyhedron. 2007;26(13):3428-3436.
doi:10.1016/j.poly.2007.03.023 .

Todorović, Tamara, Bacchi, Alessia, Juranic, Nenad O., Sladić, Dušan, Pelizzi, Giancarlo, Božić, Tatjana T., Filipović, Nenad R., Anđelković, Katarina K., "Synthesis and characterization of novel Cd(II), Zn(II) and Ni(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone. Crystal structure of bis(2-quinolinecarboxaldehyde selenosemicarbazonato)nickel(II)" in Polyhedron, 26, no. 13 (2007):3428-3436,
https://doi.org/10.1016/j.poly.2007.03.023 . .

TY  - CONF
AU  - Božić, Tatjana T.
AU  - Novaković, Irena T.
AU  - Gasic, M
AU  - Sladić, Dušan
PY  - 2005
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/752
PB  - Blackwell Publishing, Oxford
C3  - FEBS Journal / Federation of European of Biochemical Societies
T1  - Covalent modification of hexokinase by biologically active quinones
VL  - 272
SP  - 302
EP  - 302
UR  - https://hdl.handle.net/21.15107/rcub_cherry_752
ER  - 

@conference{
author = "Božić, Tatjana T. and Novaković, Irena T. and Gasic, M and Sladić, Dušan",
year = "2005",
publisher = "Blackwell Publishing, Oxford",
journal = "FEBS Journal / Federation of European of Biochemical Societies",
title = "Covalent modification of hexokinase by biologically active quinones",
volume = "272",
pages = "302-302",
url = "https://hdl.handle.net/21.15107/rcub_cherry_752"
}

Božić, T. T., Novaković, I. T., Gasic, M.,& Sladić, D.. (2005). Covalent modification of hexokinase by biologically active quinones. in FEBS Journal / Federation of European of Biochemical Societies
Blackwell Publishing, Oxford., 272, 302-302.
https://hdl.handle.net/21.15107/rcub_cherry_752

Božić TT, Novaković IT, Gasic M, Sladić D. Covalent modification of hexokinase by biologically active quinones. in FEBS Journal / Federation of European of Biochemical Societies. 2005;272:302-302.
https://hdl.handle.net/21.15107/rcub_cherry_752 .

Božić, Tatjana T., Novaković, Irena T., Gasic, M, Sladić, Dušan, "Covalent modification of hexokinase by biologically active quinones" in FEBS Journal / Federation of European of Biochemical Societies, 272 (2005):302-302,
https://hdl.handle.net/21.15107/rcub_cherry_752 .

TY  - JOUR
AU  - Sladić, Dušan
AU  - Novaković, Irena T.
AU  - Vujčić, Zoran
AU  - Božić, Tatjana T.
AU  - Božić, Nataša
AU  - Milić, Dragana
AU  - Šolaja, Bogdan A.
AU  - Gasic, MJ
PY  - 2004
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/678
AB  - The avarone/avarol quinone/hydroquinone couple shows considerable antitumor activity. In this work, covalent modification of beta-lactoglobulin by avarone and its derivatives as well as by the synthetic steroidal quinone 2,5(10)-estradiene-1,4,17-trione and its derivatives were studied. The techniques for studying chemical modification of beta-lactoglobulin by quinones were: UV/Vis spectrophotometry, SDS PAGE and isoelectrofocusing. SDS PAGE results suggest that polymerization of the protein Occurs. It Could be seen that the protein of 18 kD gives the bands of 20 kD, 36 kD, 40 kD, 45 kD, 64 kD and 128 kD depending on modification agent. The shift of the pl of the protein (5.4) upon modification toward lower values (from pl 5.0 to 5.3) indicated that lysine amino groups are the principal site of the reaction of beta-lactoglobulin with the quinones.
AB  - Hinonsko/hidrohinonski par avaron/avarol pokazuje značajnu antitumorsku aktivnost. U ovom radu proučavane su kovalentne modifikacije β-laktoglobulina avaronom, sintetičkim steroidnim hinonom 2,5(10)-estradien-1,4,17-trionom i njihovim derivatima. Tehnike za praćenje hemijske modifikacije bile su: UV/Vis spektrofotometrija, SDS PAGE i izoelektrofokusiranje. Rezultati SDS PAGE ukazuju da se dešava polimerizacija proteina.Može se videti da protein od 18 kD daje trake od 20 kD, 36 kD, 40 kD, 45 kD, 64 kD i 128 kD u zavisnosti od agensa za modifikaciju. Pomeranje pI vrednosti proteina (5,4) nakon modifikacije ka nižim vrednostima (od pI 5,0 do 5,3) pokazuje da su amino-grupe lizina glavna mesta reakcije β-laktoglobulina sa hinonima.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Protein covalent modification by biologically active quinones
T1  - Kovalentne modifikacije proteina biološki aktivnim hinonima
VL  - 69
IS  - 11
SP  - 901
EP  - 907
DO  - 10.2298/JSC0411901S
ER  - 

@article{
author = "Sladić, Dušan and Novaković, Irena T. and Vujčić, Zoran and Božić, Tatjana T. and Božić, Nataša and Milić, Dragana and Šolaja, Bogdan A. and Gasic, MJ",
year = "2004",
abstract = "The avarone/avarol quinone/hydroquinone couple shows considerable antitumor activity. In this work, covalent modification of beta-lactoglobulin by avarone and its derivatives as well as by the synthetic steroidal quinone 2,5(10)-estradiene-1,4,17-trione and its derivatives were studied. The techniques for studying chemical modification of beta-lactoglobulin by quinones were: UV/Vis spectrophotometry, SDS PAGE and isoelectrofocusing. SDS PAGE results suggest that polymerization of the protein Occurs. It Could be seen that the protein of 18 kD gives the bands of 20 kD, 36 kD, 40 kD, 45 kD, 64 kD and 128 kD depending on modification agent. The shift of the pl of the protein (5.4) upon modification toward lower values (from pl 5.0 to 5.3) indicated that lysine amino groups are the principal site of the reaction of beta-lactoglobulin with the quinones., Hinonsko/hidrohinonski par avaron/avarol pokazuje značajnu antitumorsku aktivnost. U ovom radu proučavane su kovalentne modifikacije β-laktoglobulina avaronom, sintetičkim steroidnim hinonom 2,5(10)-estradien-1,4,17-trionom i njihovim derivatima. Tehnike za praćenje hemijske modifikacije bile su: UV/Vis spektrofotometrija, SDS PAGE i izoelektrofokusiranje. Rezultati SDS PAGE ukazuju da se dešava polimerizacija proteina.Može se videti da protein od 18 kD daje trake od 20 kD, 36 kD, 40 kD, 45 kD, 64 kD i 128 kD u zavisnosti od agensa za modifikaciju. Pomeranje pI vrednosti proteina (5,4) nakon modifikacije ka nižim vrednostima (od pI 5,0 do 5,3) pokazuje da su amino-grupe lizina glavna mesta reakcije β-laktoglobulina sa hinonima.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Protein covalent modification by biologically active quinones, Kovalentne modifikacije proteina biološki aktivnim hinonima",
volume = "69",
number = "11",
pages = "901-907",
doi = "10.2298/JSC0411901S"
}

Sladić, D., Novaković, I. T., Vujčić, Z., Božić, T. T., Božić, N., Milić, D., Šolaja, B. A.,& Gasic, M.. (2004). Protein covalent modification by biologically active quinones. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 69(11), 901-907.
https://doi.org/10.2298/JSC0411901S

Sladić D, Novaković IT, Vujčić Z, Božić TT, Božić N, Milić D, Šolaja BA, Gasic M. Protein covalent modification by biologically active quinones. in Journal of the Serbian Chemical Society. 2004;69(11):901-907.
doi:10.2298/JSC0411901S .

Sladić, Dušan, Novaković, Irena T., Vujčić, Zoran, Božić, Tatjana T., Božić, Nataša, Milić, Dragana, Šolaja, Bogdan A., Gasic, MJ, "Protein covalent modification by biologically active quinones" in Journal of the Serbian Chemical Society, 69, no. 11 (2004):901-907,
https://doi.org/10.2298/JSC0411901S . .

TY  - JOUR
AU  - Novaković, Irena T.
AU  - Vujčić, Zoran
AU  - Božić, Tatjana T.
AU  - Božić, Nataša
AU  - Milosavic, N
AU  - Sladić, Dušan
PY  - 2003
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/552
AB  - The avarone/avarol quinone/hydroquinone couple. as well as their derivatives show considerable antitumor activity. In this work, covalent modifications of beta-lactogglobulin. isolated from cow milk by avarone, its model compound 2-tert-butyl-1,4-benzoquinone. and several of their alkylthio derivatives were studied. The techniques applied for as-saying the modifications were: UV/VIS spectrophotometry, SDS PAGE and isoelectrofocusing. The results of the SDS PAGE suggest that polymerisation of the protein occurs. The shift of the pI of the protein upon modification toward lower values indicates that lysine amino groups are the principal site of die reaction of beta-lactoglobulin with the quinones.
AB  - Hinonsko/hidrohinonski par avaron/avarol i njihovi derivati pokazuju značajnu antitumorsku aktivnost. U ovom radu proučavane su kovalentne modifikacije β-laktoglobulina, izolovanog iz kravljeg mleka, avaronom, njegovim model-jedinjenjem 2-tert-butil-1,4-benzohinonom i njihovim alkiltio-derivatima. Za ispitivanje modifikacija korišćene su UV/VIS spektrofotometrija, SDS PAGE i izoelektrofokusiranje. Rezultat SDS PAGE ukazuje da se protein polimerizuje. Pomeranje pI vrednosti proteina nakon modifikacije ka nižim vrednostima pokazuje da su amino grupe lizina glavna mesta reakcije β-laktoglobulina sa hinonima.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Chemical modification of beta-lactoglobulin by quinones
T1  - Hemijske modifikacije β-laktoglobulina hinonima
VL  - 68
IS  - 4-5
SP  - 243
EP  - 248
DO  - 10.2298/JSC0305243N
ER  - 

@article{
author = "Novaković, Irena T. and Vujčić, Zoran and Božić, Tatjana T. and Božić, Nataša and Milosavic, N and Sladić, Dušan",
year = "2003",
abstract = "The avarone/avarol quinone/hydroquinone couple. as well as their derivatives show considerable antitumor activity. In this work, covalent modifications of beta-lactogglobulin. isolated from cow milk by avarone, its model compound 2-tert-butyl-1,4-benzoquinone. and several of their alkylthio derivatives were studied. The techniques applied for as-saying the modifications were: UV/VIS spectrophotometry, SDS PAGE and isoelectrofocusing. The results of the SDS PAGE suggest that polymerisation of the protein occurs. The shift of the pI of the protein upon modification toward lower values indicates that lysine amino groups are the principal site of die reaction of beta-lactoglobulin with the quinones., Hinonsko/hidrohinonski par avaron/avarol i njihovi derivati pokazuju značajnu antitumorsku aktivnost. U ovom radu proučavane su kovalentne modifikacije β-laktoglobulina, izolovanog iz kravljeg mleka, avaronom, njegovim model-jedinjenjem 2-tert-butil-1,4-benzohinonom i njihovim alkiltio-derivatima. Za ispitivanje modifikacija korišćene su UV/VIS spektrofotometrija, SDS PAGE i izoelektrofokusiranje. Rezultat SDS PAGE ukazuje da se protein polimerizuje. Pomeranje pI vrednosti proteina nakon modifikacije ka nižim vrednostima pokazuje da su amino grupe lizina glavna mesta reakcije β-laktoglobulina sa hinonima.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Chemical modification of beta-lactoglobulin by quinones, Hemijske modifikacije β-laktoglobulina hinonima",
volume = "68",
number = "4-5",
pages = "243-248",
doi = "10.2298/JSC0305243N"
}

Novaković, I. T., Vujčić, Z., Božić, T. T., Božić, N., Milosavic, N.,& Sladić, D.. (2003). Chemical modification of beta-lactoglobulin by quinones. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 68(4-5), 243-248.
https://doi.org/10.2298/JSC0305243N

Novaković IT, Vujčić Z, Božić TT, Božić N, Milosavic N, Sladić D. Chemical modification of beta-lactoglobulin by quinones. in Journal of the Serbian Chemical Society. 2003;68(4-5):243-248.
doi:10.2298/JSC0305243N .

Novaković, Irena T., Vujčić, Zoran, Božić, Tatjana T., Božić, Nataša, Milosavic, N, Sladić, Dušan, "Chemical modification of beta-lactoglobulin by quinones" in Journal of the Serbian Chemical Society, 68, no. 4-5 (2003):243-248,
https://doi.org/10.2298/JSC0305243N . .

TY  - JOUR
AU  - Božić, Tatjana T.
AU  - Sladić, Dušan
AU  - Zlatović, Mario
AU  - Novaković, Irena T.
AU  - Trifunović, Snežana S.
AU  - Gasic, MJ
PY  - 2002
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/506
AB  - The regioselectivity of the reaction of conjugate addition of thiols, amines, methanol and hydrogen chloride with the monoalkyl-1,4-benzoquinones avarone and 2-tert-butyl-1,4-benzoquinone was investigated. It was shown that the regioselectivity of the reaction is influenced by the electrophilicity of position 5 in unprotonated 2-alkylquinones, the increased electrophilicity of position 6 in acidic medium, and by the acidity of the intermediate hydroquinones.
AB  - Proučavana je regioselektivnost konjugovane adicije tiola, amina, metanola i hlorovodonika na monoalkil-1,4-benzohinone avaron i 2-tert-butil-1,4-benzohinon. Pokazano je da na regioselektivnost reakcije utiču elektrofilnost položaja 5 neprotonovanih 2-alkil-hinona i povećana elektrofilnost položaja 6 u kiseloj sredini, kao i kiselost intermedijernih hidrohinona.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Regioselectivity of conjugate additions to monoalkyl-1,4-benzoquinones
T1  - Regioselektivnost konjugovane adicijena monoalkil-1,4-benzohinone
VL  - 67
IS  - 8-9
SP  - 547
EP  - 551
DO  - 10.2298/JSC0209547B
ER  - 

@article{
author = "Božić, Tatjana T. and Sladić, Dušan and Zlatović, Mario and Novaković, Irena T. and Trifunović, Snežana S. and Gasic, MJ",
year = "2002",
abstract = "The regioselectivity of the reaction of conjugate addition of thiols, amines, methanol and hydrogen chloride with the monoalkyl-1,4-benzoquinones avarone and 2-tert-butyl-1,4-benzoquinone was investigated. It was shown that the regioselectivity of the reaction is influenced by the electrophilicity of position 5 in unprotonated 2-alkylquinones, the increased electrophilicity of position 6 in acidic medium, and by the acidity of the intermediate hydroquinones., Proučavana je regioselektivnost konjugovane adicije tiola, amina, metanola i hlorovodonika na monoalkil-1,4-benzohinone avaron i 2-tert-butil-1,4-benzohinon. Pokazano je da na regioselektivnost reakcije utiču elektrofilnost položaja 5 neprotonovanih 2-alkil-hinona i povećana elektrofilnost položaja 6 u kiseloj sredini, kao i kiselost intermedijernih hidrohinona.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Regioselectivity of conjugate additions to monoalkyl-1,4-benzoquinones, Regioselektivnost konjugovane adicijena monoalkil-1,4-benzohinone",
volume = "67",
number = "8-9",
pages = "547-551",
doi = "10.2298/JSC0209547B"
}

Božić, T. T., Sladić, D., Zlatović, M., Novaković, I. T., Trifunović, S. S.,& Gasic, M.. (2002). Regioselectivity of conjugate additions to monoalkyl-1,4-benzoquinones. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 67(8-9), 547-551.
https://doi.org/10.2298/JSC0209547B

Božić TT, Sladić D, Zlatović M, Novaković IT, Trifunović SS, Gasic M. Regioselectivity of conjugate additions to monoalkyl-1,4-benzoquinones. in Journal of the Serbian Chemical Society. 2002;67(8-9):547-551.
doi:10.2298/JSC0209547B .

Božić, Tatjana T., Sladić, Dušan, Zlatović, Mario, Novaković, Irena T., Trifunović, Snežana S., Gasic, MJ, "Regioselectivity of conjugate additions to monoalkyl-1,4-benzoquinones" in Journal of the Serbian Chemical Society, 67, no. 8-9 (2002):547-551,
https://doi.org/10.2298/JSC0209547B . .