TY  - JOUR
AU  - Krstić, Gordana B.
AU  - Saidu, Muhammad Bello
AU  - Bombicz, Petra
AU  - De, Sourav
AU  - Ali, Hazhmat
AU  - Zupkó, István
AU  - Berkecz, Róbert
AU  - Gallah, Umar Shehu
AU  - Rédei, Dóra
AU  - Hohmann, Judit
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6197
AB  - Five unusual meroterpenoids based on new carbon skeletons, pauciflorins A–E (1–5), were isolated by multistep chromatographic separations of a methanol extract of the aerial parts of Centrapalus pauciflorus. Compounds 1–3 are derived by the connection of a 2-nor-chromone and a monoterpene unit, whereas 4 and 5 are dihydrochromone–monoterpene adducts with a rarely occurring orthoester functionality. The structures were solved using 1D and 2D NMR, HRESIMS, and single-crystal X-ray diffraction. Pauciflorins A–E were evaluated for antiproliferative activity against human gynecological cancer cell lines, but were inactive (IC50 < 10 μM) in each case.
PB  - American Chemical Society
T2  - Journal of Natural Products
T1  - Pauciflorins A–E, Unexpected Chromone–Monoterpene-Derived Meroterpenoids from Centrapalus pauciflorus
VL  - 86
IS  - 4
SP  - 891
EP  - 896
DO  - 10.1021/acs.jnatprod.2c01132
ER  - 

@article{
author = "Krstić, Gordana B. and Saidu, Muhammad Bello and Bombicz, Petra and De, Sourav and Ali, Hazhmat and Zupkó, István and Berkecz, Róbert and Gallah, Umar Shehu and Rédei, Dóra and Hohmann, Judit",
year = "2023",
abstract = "Five unusual meroterpenoids based on new carbon skeletons, pauciflorins A–E (1–5), were isolated by multistep chromatographic separations of a methanol extract of the aerial parts of Centrapalus pauciflorus. Compounds 1–3 are derived by the connection of a 2-nor-chromone and a monoterpene unit, whereas 4 and 5 are dihydrochromone–monoterpene adducts with a rarely occurring orthoester functionality. The structures were solved using 1D and 2D NMR, HRESIMS, and single-crystal X-ray diffraction. Pauciflorins A–E were evaluated for antiproliferative activity against human gynecological cancer cell lines, but were inactive (IC50 < 10 μM) in each case.",
publisher = "American Chemical Society",
journal = "Journal of Natural Products",
title = "Pauciflorins A–E, Unexpected Chromone–Monoterpene-Derived Meroterpenoids from Centrapalus pauciflorus",
volume = "86",
number = "4",
pages = "891-896",
doi = "10.1021/acs.jnatprod.2c01132"
}

Krstić, G. B., Saidu, M. B., Bombicz, P., De, S., Ali, H., Zupkó, I., Berkecz, R., Gallah, U. S., Rédei, D.,& Hohmann, J.. (2023). Pauciflorins A–E, Unexpected Chromone–Monoterpene-Derived Meroterpenoids from Centrapalus pauciflorus. in Journal of Natural Products
American Chemical Society., 86(4), 891-896.
https://doi.org/10.1021/acs.jnatprod.2c01132

Krstić GB, Saidu MB, Bombicz P, De S, Ali H, Zupkó I, Berkecz R, Gallah US, Rédei D, Hohmann J. Pauciflorins A–E, Unexpected Chromone–Monoterpene-Derived Meroterpenoids from Centrapalus pauciflorus. in Journal of Natural Products. 2023;86(4):891-896.
doi:10.1021/acs.jnatprod.2c01132 .

Krstić, Gordana B., Saidu, Muhammad Bello, Bombicz, Petra, De, Sourav, Ali, Hazhmat, Zupkó, István, Berkecz, Róbert, Gallah, Umar Shehu, Rédei, Dóra, Hohmann, Judit, "Pauciflorins A–E, Unexpected Chromone–Monoterpene-Derived Meroterpenoids from Centrapalus pauciflorus" in Journal of Natural Products, 86, no. 4 (2023):891-896,
https://doi.org/10.1021/acs.jnatprod.2c01132 . .