TY  - JOUR
AU  - Ivanović, Stefan
AU  - Gođevac, Dejan
AU  - Ristivojević, Petar
AU  - Zdunić, Gordana
AU  - Stojanović, Danilo
AU  - Šavikin, Katarina
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5794
AB  - IntroductionChokeberry is a plant belonging to the family Rosaceae which has a long history of edible and medicinal use. The aims of this study are: i) to investigate of HPTLC profile of the berry samples using HPTLC technique based metabolomics approach, ii) to determine the botanical origin of investigated chokeberry adulterations iii) to identify the most important botanical markers responsible for classification.MethodsA simple, rapid, and high-throughput planar chromatography (HPTLC) method was applied in combination with multivariate techniques for differentiating chokeberry samples and identification of the main metabolites of chokeberry and four common adulterants. Images of HPTLC chromatograms obtained using two different detections i.e. visible light and derivatization with natural products reagent were used as a dataset for multivariate analysis.ResultsPrincipal component analysis and Orthogonal Partial Least Squares Discriminant Analysis confirmed the discrimination of five botanically different samples and recognized their main markers such as responsible for differences between chokeberry and four common adulterants.ConclusionThe obtained results showed that the HPTLC-based metabolomics approach can be a very reliable technique for the detection of chokeberry adulteration.
T2  - Journal of Herbal Medicine
T1  - HPTLC-based metabolomics approach for the detection of chokeberry (Aronia melanocarpa (Michx.) Elliott) adulteration
VL  - 37
SP  - 100618
DO  - 10.1016/j.hermed.2022.100618
ER  - 

@article{
author = "Ivanović, Stefan and Gođevac, Dejan and Ristivojević, Petar and Zdunić, Gordana and Stojanović, Danilo and Šavikin, Katarina",
year = "2023",
abstract = "IntroductionChokeberry is a plant belonging to the family Rosaceae which has a long history of edible and medicinal use. The aims of this study are: i) to investigate of HPTLC profile of the berry samples using HPTLC technique based metabolomics approach, ii) to determine the botanical origin of investigated chokeberry adulterations iii) to identify the most important botanical markers responsible for classification.MethodsA simple, rapid, and high-throughput planar chromatography (HPTLC) method was applied in combination with multivariate techniques for differentiating chokeberry samples and identification of the main metabolites of chokeberry and four common adulterants. Images of HPTLC chromatograms obtained using two different detections i.e. visible light and derivatization with natural products reagent were used as a dataset for multivariate analysis.ResultsPrincipal component analysis and Orthogonal Partial Least Squares Discriminant Analysis confirmed the discrimination of five botanically different samples and recognized their main markers such as responsible for differences between chokeberry and four common adulterants.ConclusionThe obtained results showed that the HPTLC-based metabolomics approach can be a very reliable technique for the detection of chokeberry adulteration.",
journal = "Journal of Herbal Medicine",
title = "HPTLC-based metabolomics approach for the detection of chokeberry (Aronia melanocarpa (Michx.) Elliott) adulteration",
volume = "37",
pages = "100618",
doi = "10.1016/j.hermed.2022.100618"
}

Ivanović, S., Gođevac, D., Ristivojević, P., Zdunić, G., Stojanović, D.,& Šavikin, K.. (2023). HPTLC-based metabolomics approach for the detection of chokeberry (Aronia melanocarpa (Michx.) Elliott) adulteration. in Journal of Herbal Medicine, 37, 100618.
https://doi.org/10.1016/j.hermed.2022.100618

Ivanović S, Gođevac D, Ristivojević P, Zdunić G, Stojanović D, Šavikin K. HPTLC-based metabolomics approach for the detection of chokeberry (Aronia melanocarpa (Michx.) Elliott) adulteration. in Journal of Herbal Medicine. 2023;37:100618.
doi:10.1016/j.hermed.2022.100618 .

Ivanović, Stefan, Gođevac, Dejan, Ristivojević, Petar, Zdunić, Gordana, Stojanović, Danilo, Šavikin, Katarina, "HPTLC-based metabolomics approach for the detection of chokeberry (Aronia melanocarpa (Michx.) Elliott) adulteration" in Journal of Herbal Medicine, 37 (2023):100618,
https://doi.org/10.1016/j.hermed.2022.100618 . .

TY  - JOUR
AU  - Mudrić, Jelena
AU  - Drinić, Zorica
AU  - Zdunić, Gordana
AU  - Todosijević, Marina
AU  - Bigović, Dubravka
AU  - Menković, Nebojša
AU  - Šavikin, Katarina
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4305
AB  - Rose hip seed oil is a rich source of polyunsaturated fatty acids, as well as tocopherols, carotenoids, sterols, phospholipids, and phenolic com­pounds. On the other hand, due to the high content of polyunsaturated fatty acids, this oil is prone to oxidation. The aim of this study was to investigate the influence of a natural antioxidant, i.e., pomegranate peel extract, and its com­bination with butylated hydroxytoluene as a commonly used synthetic anti­oxidant, on the stability of rose hip oil. The stability of samples without and with different antioxidants was monitored through analysis of the fatty acid composition and measurement of the quality and stability parameters of the oil (peroxide value, p-anisidine value, thiobarbituric acid reactive substances inhi­bition, total phenolic content and antiradical activity) during a storage period of 12 days at 65 °C. Pomegranate peel extract (0.1 %) inhibited more effectively the second stage of oxidation than butylated hydroxytoluene (0.02 %), while the first stage of oxidation was better prevented by the synthetic antioxidant. Furthermore, the addition of pomegranate peel extract increased the total phen­olic content of the rose hip oil as well as its antiradical activity. Thus, pome­granate peel extract could be used as a potent natural antioxidant for the stabil­ization of beneficial but unstable rose hip oil.
T2  - Journal of the Serbian Chemical Society
T1  - Stabilization of rose hip oil by pomegranate peel extract during accelerated storage
VL  - 85
IS  - 12
SP  - 1553
EP  - 1563
DO  - 10.2298/JSC200424064M
ER  - 

@article{
author = "Mudrić, Jelena and Drinić, Zorica and Zdunić, Gordana and Todosijević, Marina and Bigović, Dubravka and Menković, Nebojša and Šavikin, Katarina",
year = "2020",
abstract = "Rose hip seed oil is a rich source of polyunsaturated fatty acids, as well as tocopherols, carotenoids, sterols, phospholipids, and phenolic com­pounds. On the other hand, due to the high content of polyunsaturated fatty acids, this oil is prone to oxidation. The aim of this study was to investigate the influence of a natural antioxidant, i.e., pomegranate peel extract, and its com­bination with butylated hydroxytoluene as a commonly used synthetic anti­oxidant, on the stability of rose hip oil. The stability of samples without and with different antioxidants was monitored through analysis of the fatty acid composition and measurement of the quality and stability parameters of the oil (peroxide value, p-anisidine value, thiobarbituric acid reactive substances inhi­bition, total phenolic content and antiradical activity) during a storage period of 12 days at 65 °C. Pomegranate peel extract (0.1 %) inhibited more effectively the second stage of oxidation than butylated hydroxytoluene (0.02 %), while the first stage of oxidation was better prevented by the synthetic antioxidant. Furthermore, the addition of pomegranate peel extract increased the total phen­olic content of the rose hip oil as well as its antiradical activity. Thus, pome­granate peel extract could be used as a potent natural antioxidant for the stabil­ization of beneficial but unstable rose hip oil.",
journal = "Journal of the Serbian Chemical Society",
title = "Stabilization of rose hip oil by pomegranate peel extract during accelerated storage",
volume = "85",
number = "12",
pages = "1553-1563",
doi = "10.2298/JSC200424064M"
}

Mudrić, J., Drinić, Z., Zdunić, G., Todosijević, M., Bigović, D., Menković, N.,& Šavikin, K.. (2020). Stabilization of rose hip oil by pomegranate peel extract during accelerated storage. in Journal of the Serbian Chemical Society, 85(12), 1553-1563.
https://doi.org/10.2298/JSC200424064M

Mudrić J, Drinić Z, Zdunić G, Todosijević M, Bigović D, Menković N, Šavikin K. Stabilization of rose hip oil by pomegranate peel extract during accelerated storage. in Journal of the Serbian Chemical Society. 2020;85(12):1553-1563.
doi:10.2298/JSC200424064M .

Mudrić, Jelena, Drinić, Zorica, Zdunić, Gordana, Todosijević, Marina, Bigović, Dubravka, Menković, Nebojša, Šavikin, Katarina, "Stabilization of rose hip oil by pomegranate peel extract during accelerated storage" in Journal of the Serbian Chemical Society, 85, no. 12 (2020):1553-1563,
https://doi.org/10.2298/JSC200424064M . .

TY  - JOUR
AU  - Damjanović, Ana
AU  - Zdunić, Gordana
AU  - Šavikin, Katarina
AU  - Mandić, Boris
AU  - Jadranin, Milka
AU  - Matić, Ivana Z.
AU  - Stanojković, Tatjana
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2366
AB  - The cytotoxicity of Mahonia aquifolium ethanol and water extracts was examined using MTT test. The morphological changes were analyzed by fluorescence microscopy. Cell cycle distribution and possible activation of caspase-dependent pathway of cell death were assessed by flow cytometry. The effects of ethanol and water extracts on migration of endothelial EA. hy926 cells were analyzed by in vitro scratch assay and inhibition of angiogenesis was detected using tube formation assay. Both extracts demonstrated cytotoxic effects on cancer cell lines with very high selectivity. Morphological evaluation indicated apoptosis. These results were confirmed with cell cycle analysis, where there was accumulation of cancer cells in the subG1 phase. Ethanol and water extracts induced a caspase-dependent apoptosis in HeLa cells through activation of caspase-3 and caspase-8. Both extracts showed the ability to inbibit the migration of EA. hy926 cells and initial steps of angiogenesis. In addition, ethanol extract exerted significant anti-angiogenic effect.
PB  - Bangladesh Pharmacological Soc, Shahbah
T2  - Bangladesh Journal of Pharmacology
T1  - Evaluation of the anti-cancer potential of Mahonia aquifolium extracts via apoptosis and anti-angiogenesis
VL  - 11
IS  - 3
SP  - 741
EP  - 749
DO  - 10.3329/bjp.v11i3.27103
ER  - 

@article{
author = "Damjanović, Ana and Zdunić, Gordana and Šavikin, Katarina and Mandić, Boris and Jadranin, Milka and Matić, Ivana Z. and Stanojković, Tatjana",
year = "2016",
abstract = "The cytotoxicity of Mahonia aquifolium ethanol and water extracts was examined using MTT test. The morphological changes were analyzed by fluorescence microscopy. Cell cycle distribution and possible activation of caspase-dependent pathway of cell death were assessed by flow cytometry. The effects of ethanol and water extracts on migration of endothelial EA. hy926 cells were analyzed by in vitro scratch assay and inhibition of angiogenesis was detected using tube formation assay. Both extracts demonstrated cytotoxic effects on cancer cell lines with very high selectivity. Morphological evaluation indicated apoptosis. These results were confirmed with cell cycle analysis, where there was accumulation of cancer cells in the subG1 phase. Ethanol and water extracts induced a caspase-dependent apoptosis in HeLa cells through activation of caspase-3 and caspase-8. Both extracts showed the ability to inbibit the migration of EA. hy926 cells and initial steps of angiogenesis. In addition, ethanol extract exerted significant anti-angiogenic effect.",
publisher = "Bangladesh Pharmacological Soc, Shahbah",
journal = "Bangladesh Journal of Pharmacology",
title = "Evaluation of the anti-cancer potential of Mahonia aquifolium extracts via apoptosis and anti-angiogenesis",
volume = "11",
number = "3",
pages = "741-749",
doi = "10.3329/bjp.v11i3.27103"
}

Damjanović, A., Zdunić, G., Šavikin, K., Mandić, B., Jadranin, M., Matić, I. Z.,& Stanojković, T.. (2016). Evaluation of the anti-cancer potential of Mahonia aquifolium extracts via apoptosis and anti-angiogenesis. in Bangladesh Journal of Pharmacology
Bangladesh Pharmacological Soc, Shahbah., 11(3), 741-749.
https://doi.org/10.3329/bjp.v11i3.27103

Damjanović A, Zdunić G, Šavikin K, Mandić B, Jadranin M, Matić IZ, Stanojković T. Evaluation of the anti-cancer potential of Mahonia aquifolium extracts via apoptosis and anti-angiogenesis. in Bangladesh Journal of Pharmacology. 2016;11(3):741-749.
doi:10.3329/bjp.v11i3.27103 .

Damjanović, Ana, Zdunić, Gordana, Šavikin, Katarina, Mandić, Boris, Jadranin, Milka, Matić, Ivana Z., Stanojković, Tatjana, "Evaluation of the anti-cancer potential of Mahonia aquifolium extracts via apoptosis and anti-angiogenesis" in Bangladesh Journal of Pharmacology, 11, no. 3 (2016):741-749,
https://doi.org/10.3329/bjp.v11i3.27103 . .

TY  - CHAP
AU  - Menković, N.
AU  - Šavikin, Katarina
AU  - Zdunić, Gordana
AU  - Milosavljević, Slobodan M.
AU  - Živković, Jelena M.
PY  - 2014
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/288
AB  - The main objectives of this study were to collect information on the use of wild medicinal plants by local people living in the high mountain region of northern Montenegro and to conduct local botanical and ecological surveys. During terrain expeditions, 412 plant species (38 endemic) were identified, and the most abundant family was Rosaceae, followed by Cupressaceae and Lamiaceae. Plant use was documented by speaking with 75 people (mean age 57, 61∈% female, 39∈% male) who were born in and residents of northern Montenegro. Information on 116 plant species belonging to 40 families for the treatment of various human ailments was gathered. Botanical families, such as Asteraceae, Rosaceae, and Lamiaceae, were represented by the highest number of species reported by informants (14, 13, and 7 species, respectively). The most frequently reported medicinal uses were ones for treating gastrointestinal and respiratory diseases. Aerial parts (33.3∈%) were found to be highly utilized plant parts followed by roots (20.8∈%) and leaves (17.3∈%). Only two endemic species (Dianthus knapii and Pinus peuce) proved useful in folk tradition. Active ingredients of plant species officinal in the European Pharmacopoeia 6.0 (Ph. Eur. 6.0) were studied, and we assessed possibilities for commercial exploitation for local economic development. This work increases the ethnobotanical data from Montenegro, safeguards local folk knowledge, and provides information on new or scarcely reported properties of medicinal plants, whose traditional use requires experimental validation. © 2014 Springer Science+Business Media New York. All rights reserved.
T2  - Ethnobotany and Biocultural Diversities in the Balkans: Perspectives on Sustainable Rural Developmen
T1  - Medicinal plants in Northern Montenegro: Traditional knowledge, quality, and resources
SP  - 197
EP  - 228
DO  - 10.1007/978-1-4939-1492-0_11
ER  - 

@inbook{
author = "Menković, N. and Šavikin, Katarina and Zdunić, Gordana and Milosavljević, Slobodan M. and Živković, Jelena M.",
year = "2014",
abstract = "The main objectives of this study were to collect information on the use of wild medicinal plants by local people living in the high mountain region of northern Montenegro and to conduct local botanical and ecological surveys. During terrain expeditions, 412 plant species (38 endemic) were identified, and the most abundant family was Rosaceae, followed by Cupressaceae and Lamiaceae. Plant use was documented by speaking with 75 people (mean age 57, 61∈% female, 39∈% male) who were born in and residents of northern Montenegro. Information on 116 plant species belonging to 40 families for the treatment of various human ailments was gathered. Botanical families, such as Asteraceae, Rosaceae, and Lamiaceae, were represented by the highest number of species reported by informants (14, 13, and 7 species, respectively). The most frequently reported medicinal uses were ones for treating gastrointestinal and respiratory diseases. Aerial parts (33.3∈%) were found to be highly utilized plant parts followed by roots (20.8∈%) and leaves (17.3∈%). Only two endemic species (Dianthus knapii and Pinus peuce) proved useful in folk tradition. Active ingredients of plant species officinal in the European Pharmacopoeia 6.0 (Ph. Eur. 6.0) were studied, and we assessed possibilities for commercial exploitation for local economic development. This work increases the ethnobotanical data from Montenegro, safeguards local folk knowledge, and provides information on new or scarcely reported properties of medicinal plants, whose traditional use requires experimental validation. © 2014 Springer Science+Business Media New York. All rights reserved.",
journal = "Ethnobotany and Biocultural Diversities in the Balkans: Perspectives on Sustainable Rural Developmen",
booktitle = "Medicinal plants in Northern Montenegro: Traditional knowledge, quality, and resources",
pages = "197-228",
doi = "10.1007/978-1-4939-1492-0_11"
}

Menković, N., Šavikin, K., Zdunić, G., Milosavljević, S. M.,& Živković, J. M.. (2014). Medicinal plants in Northern Montenegro: Traditional knowledge, quality, and resources. in Ethnobotany and Biocultural Diversities in the Balkans: Perspectives on Sustainable Rural Developmen, 197-228.
https://doi.org/10.1007/978-1-4939-1492-0_11

Menković N, Šavikin K, Zdunić G, Milosavljević SM, Živković JM. Medicinal plants in Northern Montenegro: Traditional knowledge, quality, and resources. in Ethnobotany and Biocultural Diversities in the Balkans: Perspectives on Sustainable Rural Developmen. 2014;:197-228.
doi:10.1007/978-1-4939-1492-0_11 .

Menković, N., Šavikin, Katarina, Zdunić, Gordana, Milosavljević, Slobodan M., Živković, Jelena M., "Medicinal plants in Northern Montenegro: Traditional knowledge, quality, and resources" in Ethnobotany and Biocultural Diversities in the Balkans: Perspectives on Sustainable Rural Developmen (2014):197-228,
https://doi.org/10.1007/978-1-4939-1492-0_11 . .

TY  - JOUR
AU  - Menković, N.
AU  - Šavikin, Katarina
AU  - Tasic, S.
AU  - Zdunić, Gordana
AU  - Stesevic, D.
AU  - Milosavljević, Slobodan M.
AU  - Vincek, D.
PY  - 2011
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1146
AB  - Aim of the study: The main objectives were to collect information on the use of wild growing medicinal plants by local people living in high mountain region of Montenegro and conduct local botanical and ecological surveys. Active ingredients of plant species officinal in European Pharmacopoeia 6.0 (Ph. Eur. 6.0) were studied and we assessed possibilities for commercial exploitation for local economic development. Materials and methods: The 75 people that were interviewed (40-82 years old) identified 94 species for treatment of various human ailments. For each named species, the following elements are provided: botanical name, family, part(s) used, medicinal use and perceived property, listing in published pharmacopoeias, the relative abundance of each species and locality where the plant was collected. Chemical analyses were done according to prescriptions of Ph. Eur. 6.0 in order to estimate potential commercial use of native plants. Results and conclusion: The most common in traditional usage were Rosaceae (11 species) making 11.7%, Asteraceae (10 species) 10.6% and Lamiaceae (7 species) 7.4%. From 94 species reported, 35 (37.2%) are officinal in Ph. Eur. 6.0 and 12 in national pharmacopoeias (12.8%). Aerial parts were mostly used (43.6%). The most frequently reported medicinal uses were for treating gastrointestinal (57.4%) and respiratory diseases (41.5%). (C) 2010 Elsevier Ireland Ltd. All rights reserved.
PB  - Elsevier Ireland Ltd, Clare
T2  - Journal of Ethnopharmacology
T1  - Ethnobotanical study on traditional uses of wild medicinal plants in Prokletije Mountains (Montenegro)
VL  - 133
IS  - 1
SP  - 97
EP  - 107
DO  - 10.1016/j.jep.2010.09.008
ER  - 

@article{
author = "Menković, N. and Šavikin, Katarina and Tasic, S. and Zdunić, Gordana and Stesevic, D. and Milosavljević, Slobodan M. and Vincek, D.",
year = "2011",
abstract = "Aim of the study: The main objectives were to collect information on the use of wild growing medicinal plants by local people living in high mountain region of Montenegro and conduct local botanical and ecological surveys. Active ingredients of plant species officinal in European Pharmacopoeia 6.0 (Ph. Eur. 6.0) were studied and we assessed possibilities for commercial exploitation for local economic development. Materials and methods: The 75 people that were interviewed (40-82 years old) identified 94 species for treatment of various human ailments. For each named species, the following elements are provided: botanical name, family, part(s) used, medicinal use and perceived property, listing in published pharmacopoeias, the relative abundance of each species and locality where the plant was collected. Chemical analyses were done according to prescriptions of Ph. Eur. 6.0 in order to estimate potential commercial use of native plants. Results and conclusion: The most common in traditional usage were Rosaceae (11 species) making 11.7%, Asteraceae (10 species) 10.6% and Lamiaceae (7 species) 7.4%. From 94 species reported, 35 (37.2%) are officinal in Ph. Eur. 6.0 and 12 in national pharmacopoeias (12.8%). Aerial parts were mostly used (43.6%). The most frequently reported medicinal uses were for treating gastrointestinal (57.4%) and respiratory diseases (41.5%). (C) 2010 Elsevier Ireland Ltd. All rights reserved.",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Journal of Ethnopharmacology",
title = "Ethnobotanical study on traditional uses of wild medicinal plants in Prokletije Mountains (Montenegro)",
volume = "133",
number = "1",
pages = "97-107",
doi = "10.1016/j.jep.2010.09.008"
}

Menković, N., Šavikin, K., Tasic, S., Zdunić, G., Stesevic, D., Milosavljević, S. M.,& Vincek, D.. (2011). Ethnobotanical study on traditional uses of wild medicinal plants in Prokletije Mountains (Montenegro). in Journal of Ethnopharmacology
Elsevier Ireland Ltd, Clare., 133(1), 97-107.
https://doi.org/10.1016/j.jep.2010.09.008

Menković N, Šavikin K, Tasic S, Zdunić G, Stesevic D, Milosavljević SM, Vincek D. Ethnobotanical study on traditional uses of wild medicinal plants in Prokletije Mountains (Montenegro). in Journal of Ethnopharmacology. 2011;133(1):97-107.
doi:10.1016/j.jep.2010.09.008 .

Menković, N., Šavikin, Katarina, Tasic, S., Zdunić, Gordana, Stesevic, D., Milosavljević, Slobodan M., Vincek, D., "Ethnobotanical study on traditional uses of wild medicinal plants in Prokletije Mountains (Montenegro)" in Journal of Ethnopharmacology, 133, no. 1 (2011):97-107,
https://doi.org/10.1016/j.jep.2010.09.008 . .

TY  - JOUR
AU  - Zdunić, Gordana
AU  - Gođevac, Dejan
AU  - Šavikin, Katarina
AU  - Novaković, Miroslav M.
AU  - Milosavljević, Slobodan M.
AU  - Petrović, Silvana
PY  - 2011
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1148
AB  - The chemical composition and free radical scavenging properties of the MeOH extract of Hypericum richeri and its subsequent CHCl3, n-BuOH, EtOAc and aqueous extracts were investigated. Four quercetin-3-O-glycosides, three myricetin-3-O-glycosides, 3-O- and 5-O-caffeoylquinic acid, quercetin, I3,II8-biapigenin, pseudohypericin and hypericin were identified. The constituents of the extracts were quantified using HPLC-DAD (high-performance liquid chromatography-diode array detector). Isolation of the compounds from n-BuOH and EtOAc extracts was conducted by column chromatography. Antioxidant capacity of the extracts was evaluated by superoxide radical and ABTS root+ scavenging assays and inhibition of lipid peroxidation. The EtOAc extract of H. richeri was the most potent antioxidant in all experiments. Free radical scavenging compounds were identified by HPLC-DPPH root (high-performance liquid chromatography-2,2-diphenyl-1-picrylhydrazyl) post-column derivatisation method, where all phenolic compounds except I3,II8-biapigenin exhibited radical scavenging properties. This is the first report of the presence of myricetin-3-O-rutinoside, myricetin-3-O-galactoside, myricetin-3-O-glucoside, 5-O-caffeoylquinic acid and I3,II8-biapigenin in H. richeri.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Isolation and identification of phenolic compounds from Hypericum richeri Vill. and their antioxidant capacity
VL  - 25
IS  - 3
SP  - 175
EP  - 187
DO  - 10.1080/14786410802401390
ER  - 

@article{
author = "Zdunić, Gordana and Gođevac, Dejan and Šavikin, Katarina and Novaković, Miroslav M. and Milosavljević, Slobodan M. and Petrović, Silvana",
year = "2011",
abstract = "The chemical composition and free radical scavenging properties of the MeOH extract of Hypericum richeri and its subsequent CHCl3, n-BuOH, EtOAc and aqueous extracts were investigated. Four quercetin-3-O-glycosides, three myricetin-3-O-glycosides, 3-O- and 5-O-caffeoylquinic acid, quercetin, I3,II8-biapigenin, pseudohypericin and hypericin were identified. The constituents of the extracts were quantified using HPLC-DAD (high-performance liquid chromatography-diode array detector). Isolation of the compounds from n-BuOH and EtOAc extracts was conducted by column chromatography. Antioxidant capacity of the extracts was evaluated by superoxide radical and ABTS root+ scavenging assays and inhibition of lipid peroxidation. The EtOAc extract of H. richeri was the most potent antioxidant in all experiments. Free radical scavenging compounds were identified by HPLC-DPPH root (high-performance liquid chromatography-2,2-diphenyl-1-picrylhydrazyl) post-column derivatisation method, where all phenolic compounds except I3,II8-biapigenin exhibited radical scavenging properties. This is the first report of the presence of myricetin-3-O-rutinoside, myricetin-3-O-galactoside, myricetin-3-O-glucoside, 5-O-caffeoylquinic acid and I3,II8-biapigenin in H. richeri.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Isolation and identification of phenolic compounds from Hypericum richeri Vill. and their antioxidant capacity",
volume = "25",
number = "3",
pages = "175-187",
doi = "10.1080/14786410802401390"
}

Zdunić, G., Gođevac, D., Šavikin, K., Novaković, M. M., Milosavljević, S. M.,& Petrović, S.. (2011). Isolation and identification of phenolic compounds from Hypericum richeri Vill. and their antioxidant capacity. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 25(3), 175-187.
https://doi.org/10.1080/14786410802401390

Zdunić G, Gođevac D, Šavikin K, Novaković MM, Milosavljević SM, Petrović S. Isolation and identification of phenolic compounds from Hypericum richeri Vill. and their antioxidant capacity. in Natural Product Research. 2011;25(3):175-187.
doi:10.1080/14786410802401390 .

Zdunić, Gordana, Gođevac, Dejan, Šavikin, Katarina, Novaković, Miroslav M., Milosavljević, Slobodan M., Petrović, Silvana, "Isolation and identification of phenolic compounds from Hypericum richeri Vill. and their antioxidant capacity" in Natural Product Research, 25, no. 3 (2011):175-187,
https://doi.org/10.1080/14786410802401390 . .

TY  - JOUR
AU  - Jankovic, Teodora
AU  - Krstic-Milosevic, Dijana
AU  - Aljančić, Ivana
AU  - Šavikin, Katarina
AU  - Menkovic, Nebojsa
AU  - Radanović, Dragoja
AU  - Milosavljević, Slobodan M.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/615
AB  - Xanthone-O-glycosides with 1,3,7,8-oxidation pattern and flavone isoorientin-3'-O-glucoside were isolated from the aerial parts of Gentiana utriculosa. Xanthone-C-glucoside lancerin was detected in Gentiana species for the first time. The distribution of these compounds within the section Calathianae is discussed.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Phytochemical re-investigation of Gentiana utriculosa
VL  - 23
IS  - 5
SP  - 466
EP  - 469
DO  - 10.1080/14786410802079477
ER  - 

@article{
author = "Jankovic, Teodora and Krstic-Milosevic, Dijana and Aljančić, Ivana and Šavikin, Katarina and Menkovic, Nebojsa and Radanović, Dragoja and Milosavljević, Slobodan M.",
year = "2009",
abstract = "Xanthone-O-glycosides with 1,3,7,8-oxidation pattern and flavone isoorientin-3'-O-glucoside were isolated from the aerial parts of Gentiana utriculosa. Xanthone-C-glucoside lancerin was detected in Gentiana species for the first time. The distribution of these compounds within the section Calathianae is discussed.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Phytochemical re-investigation of Gentiana utriculosa",
volume = "23",
number = "5",
pages = "466-469",
doi = "10.1080/14786410802079477"
}

Jankovic, T., Krstic-Milosevic, D., Aljančić, I., Šavikin, K., Menkovic, N., Radanović, D.,& Milosavljević, S. M.. (2009). Phytochemical re-investigation of Gentiana utriculosa. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 23(5), 466-469.
https://doi.org/10.1080/14786410802079477

Jankovic T, Krstic-Milosevic D, Aljančić I, Šavikin K, Menkovic N, Radanović D, Milosavljević SM. Phytochemical re-investigation of Gentiana utriculosa. in Natural Product Research. 2009;23(5):466-469.
doi:10.1080/14786410802079477 .

Jankovic, Teodora, Krstic-Milosevic, Dijana, Aljančić, Ivana, Šavikin, Katarina, Menkovic, Nebojsa, Radanović, Dragoja, Milosavljević, Slobodan M., "Phytochemical re-investigation of Gentiana utriculosa" in Natural Product Research, 23, no. 5 (2009):466-469,
https://doi.org/10.1080/14786410802079477 . .

TY  - JOUR
AU  - Gođevac, Dejan
AU  - Pejin, Boris
AU  - Zdunić, Gordana
AU  - Šavikin, Katarina
AU  - Stesevic, Danijela
AU  - Vajs, Vlatka
AU  - Milosavljević, Slobodan M.
PY  - 2008
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/943
AB  - Rutin (1, main constituent) and two flavone C-glycosides, vitexin (2) and vitexin 2 ''-O-alpha-rhamnopyranoside (3) were isolated from the aerial parts of Onobrychis montana subsp. scardica. They were identified by (1)H-NMR, (13)C-NMR and UV-Vis spectroscopy (procedure with shift reagents), and high resolution ESI-MS. A relatively high content of 1 (5.27 mg/g of dry plant material), measured by HPLC, indicated O. montana subsp. scardica as a new natural source of this biologically active compound. The isolated flavonoid compounds might be of value as chemotaxonomic markers.
AB  - Iz nadzemnih delova Onobrychis montana subsp. scardica izolovani su rutin (1, glavni sastojak) i dva flavonoidna S-glikozida, viteksin (2) i njegov 2''-O-α-ramnopiranozid (3). Njihova struktura je određena primenom 1H-NMR, 13C-NMR i UV spektroskopije (procedura sa reagensima UV-pomeranja) i masene spektrometrije visokog razlaganja (HR-ESI-MS). Relativno visok sadržaj rutina (5.27 mg/g suvog materijala) određen pomoću tečne hromatografije (HPLC), ukazuje na O. montana subsp. scardica kao nov prirodni izvor ovog biološki aktivnog jedinjenja. Izolovana jedinjenja mogu biti i od vrednosti kao hemotaksonomski markeri.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Flavonoids from the aerial parts of Onobrychis montana subsp scardica
T1  - Flavonoidi iz nadzemnih delova Onobrychis montana subsp. scardica
VL  - 73
IS  - 5
SP  - 525
EP  - 529
DO  - 10.2298/JSC0805525G
ER  - 

@article{
author = "Gođevac, Dejan and Pejin, Boris and Zdunić, Gordana and Šavikin, Katarina and Stesevic, Danijela and Vajs, Vlatka and Milosavljević, Slobodan M.",
year = "2008",
abstract = "Rutin (1, main constituent) and two flavone C-glycosides, vitexin (2) and vitexin 2 ''-O-alpha-rhamnopyranoside (3) were isolated from the aerial parts of Onobrychis montana subsp. scardica. They were identified by (1)H-NMR, (13)C-NMR and UV-Vis spectroscopy (procedure with shift reagents), and high resolution ESI-MS. A relatively high content of 1 (5.27 mg/g of dry plant material), measured by HPLC, indicated O. montana subsp. scardica as a new natural source of this biologically active compound. The isolated flavonoid compounds might be of value as chemotaxonomic markers., Iz nadzemnih delova Onobrychis montana subsp. scardica izolovani su rutin (1, glavni sastojak) i dva flavonoidna S-glikozida, viteksin (2) i njegov 2''-O-α-ramnopiranozid (3). Njihova struktura je određena primenom 1H-NMR, 13C-NMR i UV spektroskopije (procedura sa reagensima UV-pomeranja) i masene spektrometrije visokog razlaganja (HR-ESI-MS). Relativno visok sadržaj rutina (5.27 mg/g suvog materijala) određen pomoću tečne hromatografije (HPLC), ukazuje na O. montana subsp. scardica kao nov prirodni izvor ovog biološki aktivnog jedinjenja. Izolovana jedinjenja mogu biti i od vrednosti kao hemotaksonomski markeri.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Flavonoids from the aerial parts of Onobrychis montana subsp scardica, Flavonoidi iz nadzemnih delova Onobrychis montana subsp. scardica",
volume = "73",
number = "5",
pages = "525-529",
doi = "10.2298/JSC0805525G"
}

Gođevac, D., Pejin, B., Zdunić, G., Šavikin, K., Stesevic, D., Vajs, V.,& Milosavljević, S. M.. (2008). Flavonoids from the aerial parts of Onobrychis montana subsp scardica. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 73(5), 525-529.
https://doi.org/10.2298/JSC0805525G

Gođevac D, Pejin B, Zdunić G, Šavikin K, Stesevic D, Vajs V, Milosavljević SM. Flavonoids from the aerial parts of Onobrychis montana subsp scardica. in Journal of the Serbian Chemical Society. 2008;73(5):525-529.
doi:10.2298/JSC0805525G .

Gođevac, Dejan, Pejin, Boris, Zdunić, Gordana, Šavikin, Katarina, Stesevic, Danijela, Vajs, Vlatka, Milosavljević, Slobodan M., "Flavonoids from the aerial parts of Onobrychis montana subsp scardica" in Journal of the Serbian Chemical Society, 73, no. 5 (2008):525-529,
https://doi.org/10.2298/JSC0805525G . .