TY  - JOUR
AU  - Trajković, Milos
AU  - Ferjančić, Zorana
AU  - Saičić, Radomir
AU  - Bihelović, Filip
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2869
AB  - A chiral-pool-based synthesis of the platensimycin core was achieved using (S)-lactic acid as an inexpensive starting material. The cyclohexenone ring was closed in a Mukaiyama–Michael domino sequence, while the quaternary stereocenter was created by a highly stereoselective decarboxylative allylation. The spirobicyclic skeleton was constructed by a RCM reaction. A new silver(I)-promoted cyclization reaction of Δ 6 - and Δ 7 -α-iodoketones was developed and applied for the pivotal carbon–carbon bond formation. The scope and limitations of this methodology are also presented.
PB  - Wiley
T2  - Chemistry - A European Journal
T1  - Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone
VL  - 25
IS  - 17
SP  - 4340
EP  - 4344
DO  - 10.1002/chem.201900497
ER  - 

@article{
author = "Trajković, Milos and Ferjančić, Zorana and Saičić, Radomir and Bihelović, Filip",
year = "2019",
abstract = "A chiral-pool-based synthesis of the platensimycin core was achieved using (S)-lactic acid as an inexpensive starting material. The cyclohexenone ring was closed in a Mukaiyama–Michael domino sequence, while the quaternary stereocenter was created by a highly stereoselective decarboxylative allylation. The spirobicyclic skeleton was constructed by a RCM reaction. A new silver(I)-promoted cyclization reaction of Δ 6 - and Δ 7 -α-iodoketones was developed and applied for the pivotal carbon–carbon bond formation. The scope and limitations of this methodology are also presented.",
publisher = "Wiley",
journal = "Chemistry - A European Journal",
title = "Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone",
volume = "25",
number = "17",
pages = "4340-4344",
doi = "10.1002/chem.201900497"
}

Trajković, M., Ferjančić, Z., Saičić, R.,& Bihelović, F.. (2019). Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone. in Chemistry - A European Journal
Wiley., 25(17), 4340-4344.
https://doi.org/10.1002/chem.201900497

Trajković M, Ferjančić Z, Saičić R, Bihelović F. Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone. in Chemistry - A European Journal. 2019;25(17):4340-4344.
doi:10.1002/chem.201900497 .

Trajković, Milos, Ferjančić, Zorana, Saičić, Radomir, Bihelović, Filip, "Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone" in Chemistry - A European Journal, 25, no. 17 (2019):4340-4344,
https://doi.org/10.1002/chem.201900497 . .

TY  - JOUR
AU  - Trajković, Milos
AU  - Ferjančić, Zorana
AU  - Saičić, Radomir
AU  - Bihelović, Filip
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2874
AB  - A chiral-pool-based synthesis of the platensimycin core was achieved using (S)-lactic acid as an inexpensive starting material. The cyclohexenone ring was closed in a Mukaiyama–Michael domino sequence, while the quaternary stereocenter was created by a highly stereoselective decarboxylative allylation. The spirobicyclic skeleton was constructed by a RCM reaction. A new silver(I)-promoted cyclization reaction of Δ 6 - and Δ 7 -α-iodoketones was developed and applied for the pivotal carbon–carbon bond formation. The scope and limitations of this methodology are also presented.
PB  - Wiley
T2  - Chemistry - A European Journal
T1  - Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone
VL  - 25
IS  - 17
SP  - 4340
EP  - 4344
DO  - 10.1002/chem.201900497
ER  - 

@article{
author = "Trajković, Milos and Ferjančić, Zorana and Saičić, Radomir and Bihelović, Filip",
year = "2019",
abstract = "A chiral-pool-based synthesis of the platensimycin core was achieved using (S)-lactic acid as an inexpensive starting material. The cyclohexenone ring was closed in a Mukaiyama–Michael domino sequence, while the quaternary stereocenter was created by a highly stereoselective decarboxylative allylation. The spirobicyclic skeleton was constructed by a RCM reaction. A new silver(I)-promoted cyclization reaction of Δ 6 - and Δ 7 -α-iodoketones was developed and applied for the pivotal carbon–carbon bond formation. The scope and limitations of this methodology are also presented.",
publisher = "Wiley",
journal = "Chemistry - A European Journal",
title = "Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone",
volume = "25",
number = "17",
pages = "4340-4344",
doi = "10.1002/chem.201900497"
}

Trajković, M., Ferjančić, Z., Saičić, R.,& Bihelović, F.. (2019). Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone. in Chemistry - A European Journal
Wiley., 25(17), 4340-4344.
https://doi.org/10.1002/chem.201900497

Trajković M, Ferjančić Z, Saičić R, Bihelović F. Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone. in Chemistry - A European Journal. 2019;25(17):4340-4344.
doi:10.1002/chem.201900497 .

Trajković, Milos, Ferjančić, Zorana, Saičić, Radomir, Bihelović, Filip, "Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone" in Chemistry - A European Journal, 25, no. 17 (2019):4340-4344,
https://doi.org/10.1002/chem.201900497 . .

TY  - DATA
AU  - Trajković, Milos
AU  - Ferjančić, Zorana
AU  - Saičić, Radomir
AU  - Bihelović, Filip
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3842
PB  - Wiley
T2  - Chemistry - A European Journal
T1  - Supplementary data for the article: Trajkovic, M.; Ferjancic, Z.; Saicic, R. N.; Bihelovic, F. Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone. Chemistry - A European Journal 2019, 25 (17), 4340–4344. https://doi.org/10.1002/chem.201900497
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3842
ER  - 

@misc{
author = "Trajković, Milos and Ferjančić, Zorana and Saičić, Radomir and Bihelović, Filip",
year = "2019",
publisher = "Wiley",
journal = "Chemistry - A European Journal",
title = "Supplementary data for the article: Trajkovic, M.; Ferjancic, Z.; Saicic, R. N.; Bihelovic, F. Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone. Chemistry - A European Journal 2019, 25 (17), 4340–4344. https://doi.org/10.1002/chem.201900497",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3842"
}

Trajković, M., Ferjančić, Z., Saičić, R.,& Bihelović, F.. (2019). Supplementary data for the article: Trajkovic, M.; Ferjancic, Z.; Saicic, R. N.; Bihelovic, F. Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone. Chemistry - A European Journal 2019, 25 (17), 4340–4344. https://doi.org/10.1002/chem.201900497. in Chemistry - A European Journal
Wiley..
https://hdl.handle.net/21.15107/rcub_cherry_3842

Trajković M, Ferjančić Z, Saičić R, Bihelović F. Supplementary data for the article: Trajkovic, M.; Ferjancic, Z.; Saicic, R. N.; Bihelovic, F. Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone. Chemistry - A European Journal 2019, 25 (17), 4340–4344. https://doi.org/10.1002/chem.201900497. in Chemistry - A European Journal. 2019;.
https://hdl.handle.net/21.15107/rcub_cherry_3842 .

Trajković, Milos, Ferjančić, Zorana, Saičić, Radomir, Bihelović, Filip, "Supplementary data for the article: Trajkovic, M.; Ferjancic, Z.; Saicic, R. N.; Bihelovic, F. Enantioselective Synthesis of the Platensimycin Core by Silver(I)-Promoted Cyclization of Δ 6 -α-Iodoketone. Chemistry - A European Journal 2019, 25 (17), 4340–4344. https://doi.org/10.1002/chem.201900497" in Chemistry - A European Journal (2019),
https://hdl.handle.net/21.15107/rcub_cherry_3842 .

TY  - JOUR
AU  - Trajković, Milos
AU  - Balanac, Vesna
AU  - Ferjančić, Zorana
AU  - Saičić, Radomir
PY  - 2014
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1876
AB  - Enantioselective synthesis of (+)-swainsonine was achieved in 9 steps, with 24% overall yield. The key feature of the synthesis is the tactical combination of reactions: organocatalyzed aldolization/reductive amination, which allows for a rapid construction of highly functionalized heterocyclic systems. In a similar way (+)-8-epi-swainsonine was synthesized (7 steps, 28%).
PB  - Royal Soc Chemistry, Cambridge
T2  - RSC Advances
T1  - Total synthesis of (+)-swainsonine and (+)-8-epi-swainsonine
VL  - 4
IS  - 96
SP  - 53722
EP  - 53724
DO  - 10.1039/c4ra11978a
ER  - 

@article{
author = "Trajković, Milos and Balanac, Vesna and Ferjančić, Zorana and Saičić, Radomir",
year = "2014",
abstract = "Enantioselective synthesis of (+)-swainsonine was achieved in 9 steps, with 24% overall yield. The key feature of the synthesis is the tactical combination of reactions: organocatalyzed aldolization/reductive amination, which allows for a rapid construction of highly functionalized heterocyclic systems. In a similar way (+)-8-epi-swainsonine was synthesized (7 steps, 28%).",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "RSC Advances",
title = "Total synthesis of (+)-swainsonine and (+)-8-epi-swainsonine",
volume = "4",
number = "96",
pages = "53722-53724",
doi = "10.1039/c4ra11978a"
}

Trajković, M., Balanac, V., Ferjančić, Z.,& Saičić, R.. (2014). Total synthesis of (+)-swainsonine and (+)-8-epi-swainsonine. in RSC Advances
Royal Soc Chemistry, Cambridge., 4(96), 53722-53724.
https://doi.org/10.1039/c4ra11978a

Trajković M, Balanac V, Ferjančić Z, Saičić R. Total synthesis of (+)-swainsonine and (+)-8-epi-swainsonine. in RSC Advances. 2014;4(96):53722-53724.
doi:10.1039/c4ra11978a .

Trajković, Milos, Balanac, Vesna, Ferjančić, Zorana, Saičić, Radomir, "Total synthesis of (+)-swainsonine and (+)-8-epi-swainsonine" in RSC Advances, 4, no. 96 (2014):53722-53724,
https://doi.org/10.1039/c4ra11978a . .

TY  - DATA
AU  - Trajković, Milos
AU  - Ferjančić, Zorana
AU  - Saičić, Radomir
PY  - 2013
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3495
PB  - Georg Thieme Verlag Kg, Stuttgart
T2  - Synthesis, Stuttgart
T1  - Supplementary data for article: Trajković, M.; Ferjančić, Z.; Saičić, R. Formal Synthesis of (-)-Oseltamivir Phosphate. Synthesis, Stuttgart 2013, 45 (3), 389–395. https://doi.org/10.1055/s-0032-1317948
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3495
ER  - 

@misc{
author = "Trajković, Milos and Ferjančić, Zorana and Saičić, Radomir",
year = "2013",
publisher = "Georg Thieme Verlag Kg, Stuttgart",
journal = "Synthesis, Stuttgart",
title = "Supplementary data for article: Trajković, M.; Ferjančić, Z.; Saičić, R. Formal Synthesis of (-)-Oseltamivir Phosphate. Synthesis, Stuttgart 2013, 45 (3), 389–395. https://doi.org/10.1055/s-0032-1317948",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3495"
}

Trajković, M., Ferjančić, Z.,& Saičić, R.. (2013). Supplementary data for article: Trajković, M.; Ferjančić, Z.; Saičić, R. Formal Synthesis of (-)-Oseltamivir Phosphate. Synthesis, Stuttgart 2013, 45 (3), 389–395. https://doi.org/10.1055/s-0032-1317948. in Synthesis, Stuttgart
Georg Thieme Verlag Kg, Stuttgart..
https://hdl.handle.net/21.15107/rcub_cherry_3495

Trajković M, Ferjančić Z, Saičić R. Supplementary data for article: Trajković, M.; Ferjančić, Z.; Saičić, R. Formal Synthesis of (-)-Oseltamivir Phosphate. Synthesis, Stuttgart 2013, 45 (3), 389–395. https://doi.org/10.1055/s-0032-1317948. in Synthesis, Stuttgart. 2013;.
https://hdl.handle.net/21.15107/rcub_cherry_3495 .

Trajković, Milos, Ferjančić, Zorana, Saičić, Radomir, "Supplementary data for article: Trajković, M.; Ferjančić, Z.; Saičić, R. Formal Synthesis of (-)-Oseltamivir Phosphate. Synthesis, Stuttgart 2013, 45 (3), 389–395. https://doi.org/10.1055/s-0032-1317948" in Synthesis, Stuttgart (2013),
https://hdl.handle.net/21.15107/rcub_cherry_3495 .

TY  - JOUR
AU  - Trajković, Milos
AU  - Ferjančić, Zorana
AU  - Saičić, Radomir
PY  - 2013
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1596
AB  - The formal synthesis of (-)-oseltamivir phosphate (Tamiflu (TM)) was accomplished starting from (S)-pyroglutamic acid. The synthesis comprised two carbon-carbon bond forming reactions, the first one being a diastereoselective, indium-mediated allylation of a pyroglutamic aldehyde derivative. However, attempts to effect the second carbon-carbon bond formation - cyclohexene ring closure - using an enol-exo aldolization of a dialdehyde resulted in the formation of a product with the opposite regioselectivity. This shortcoming could be overcome by using a reaction sequence of Mannich methylenation/ring-closing metathesis, which provided the desired regioisomer in high yield.
PB  - Georg Thieme Verlag Kg, Stuttgart
T2  - Synthesis, Stuttgart
T1  - Formal Synthesis of (-)-Oseltamivir Phosphate
VL  - 45
IS  - 3
SP  - 389
EP  - 395
DO  - 10.1055/s-0032-1317948
ER  - 

@article{
author = "Trajković, Milos and Ferjančić, Zorana and Saičić, Radomir",
year = "2013",
abstract = "The formal synthesis of (-)-oseltamivir phosphate (Tamiflu (TM)) was accomplished starting from (S)-pyroglutamic acid. The synthesis comprised two carbon-carbon bond forming reactions, the first one being a diastereoselective, indium-mediated allylation of a pyroglutamic aldehyde derivative. However, attempts to effect the second carbon-carbon bond formation - cyclohexene ring closure - using an enol-exo aldolization of a dialdehyde resulted in the formation of a product with the opposite regioselectivity. This shortcoming could be overcome by using a reaction sequence of Mannich methylenation/ring-closing metathesis, which provided the desired regioisomer in high yield.",
publisher = "Georg Thieme Verlag Kg, Stuttgart",
journal = "Synthesis, Stuttgart",
title = "Formal Synthesis of (-)-Oseltamivir Phosphate",
volume = "45",
number = "3",
pages = "389-395",
doi = "10.1055/s-0032-1317948"
}

Trajković, M., Ferjančić, Z.,& Saičić, R.. (2013). Formal Synthesis of (-)-Oseltamivir Phosphate. in Synthesis, Stuttgart
Georg Thieme Verlag Kg, Stuttgart., 45(3), 389-395.
https://doi.org/10.1055/s-0032-1317948

Trajković M, Ferjančić Z, Saičić R. Formal Synthesis of (-)-Oseltamivir Phosphate. in Synthesis, Stuttgart. 2013;45(3):389-395.
doi:10.1055/s-0032-1317948 .

Trajković, Milos, Ferjančić, Zorana, Saičić, Radomir, "Formal Synthesis of (-)-Oseltamivir Phosphate" in Synthesis, Stuttgart, 45, no. 3 (2013):389-395,
https://doi.org/10.1055/s-0032-1317948 . .

TY  - JOUR
AU  - Trajković, Milos
AU  - Ferjančić, Zorana
AU  - Saičić, Radomir
PY  - 2012
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1318
AB  - The palladium/silane reduction of a serine thioester derivative allows for the preparation of enantiomerically pure Garner's aldehyde from serine, in gram quantities within 24 h.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Tetrahedron Asymmetry
T1  - A convenient procedure for the preparation of Garner's aldehyde
VL  - 23
IS  - 8
SP  - 602
EP  - 604
DO  - 10.1016/j.tetasy.2012.03.019
ER  - 

@article{
author = "Trajković, Milos and Ferjančić, Zorana and Saičić, Radomir",
year = "2012",
abstract = "The palladium/silane reduction of a serine thioester derivative allows for the preparation of enantiomerically pure Garner's aldehyde from serine, in gram quantities within 24 h.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Tetrahedron Asymmetry",
title = "A convenient procedure for the preparation of Garner's aldehyde",
volume = "23",
number = "8",
pages = "602-604",
doi = "10.1016/j.tetasy.2012.03.019"
}

Trajković, M., Ferjančić, Z.,& Saičić, R.. (2012). A convenient procedure for the preparation of Garner's aldehyde. in Tetrahedron Asymmetry
Pergamon-Elsevier Science Ltd, Oxford., 23(8), 602-604.
https://doi.org/10.1016/j.tetasy.2012.03.019

Trajković M, Ferjančić Z, Saičić R. A convenient procedure for the preparation of Garner's aldehyde. in Tetrahedron Asymmetry. 2012;23(8):602-604.
doi:10.1016/j.tetasy.2012.03.019 .

Trajković, Milos, Ferjančić, Zorana, Saičić, Radomir, "A convenient procedure for the preparation of Garner's aldehyde" in Tetrahedron Asymmetry, 23, no. 8 (2012):602-604,
https://doi.org/10.1016/j.tetasy.2012.03.019 . .

TY  - DATA
AU  - Trajković, Milos
AU  - Ferjančić, Zorana
AU  - Saičić, Radomir
PY  - 2011
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3571
PB  - Royal Soc Chemistry, Cambridge
T2  - Organic and Biomolecular Chemistry
T1  - Supplementary data for article: Trajković, M.; Ferjančić, Z.; Saičić, R. An Aldol Approach to the Enantioselective Synthesis of (-)-Oseltamivir Phosphate. Organic and Biomolecular Chemistry 2011, 9 (20), 6927–6929. https://doi.org/10.1039/c1ob06248d
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3571
ER  - 

@misc{
author = "Trajković, Milos and Ferjančić, Zorana and Saičić, Radomir",
year = "2011",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Organic and Biomolecular Chemistry",
title = "Supplementary data for article: Trajković, M.; Ferjančić, Z.; Saičić, R. An Aldol Approach to the Enantioselective Synthesis of (-)-Oseltamivir Phosphate. Organic and Biomolecular Chemistry 2011, 9 (20), 6927–6929. https://doi.org/10.1039/c1ob06248d",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3571"
}

Trajković, M., Ferjančić, Z.,& Saičić, R.. (2011). Supplementary data for article: Trajković, M.; Ferjančić, Z.; Saičić, R. An Aldol Approach to the Enantioselective Synthesis of (-)-Oseltamivir Phosphate. Organic and Biomolecular Chemistry 2011, 9 (20), 6927–6929. https://doi.org/10.1039/c1ob06248d. in Organic and Biomolecular Chemistry
Royal Soc Chemistry, Cambridge..
https://hdl.handle.net/21.15107/rcub_cherry_3571

Trajković M, Ferjančić Z, Saičić R. Supplementary data for article: Trajković, M.; Ferjančić, Z.; Saičić, R. An Aldol Approach to the Enantioselective Synthesis of (-)-Oseltamivir Phosphate. Organic and Biomolecular Chemistry 2011, 9 (20), 6927–6929. https://doi.org/10.1039/c1ob06248d. in Organic and Biomolecular Chemistry. 2011;.
https://hdl.handle.net/21.15107/rcub_cherry_3571 .

Trajković, Milos, Ferjančić, Zorana, Saičić, Radomir, "Supplementary data for article: Trajković, M.; Ferjančić, Z.; Saičić, R. An Aldol Approach to the Enantioselective Synthesis of (-)-Oseltamivir Phosphate. Organic and Biomolecular Chemistry 2011, 9 (20), 6927–6929. https://doi.org/10.1039/c1ob06248d" in Organic and Biomolecular Chemistry (2011),
https://hdl.handle.net/21.15107/rcub_cherry_3571 .

TY  - JOUR
AU  - Trajković, Milos
AU  - Ferjančić, Zorana
AU  - Saičić, Radomir
PY  - 2011
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1210
AB  - A formal asymmetric synthesis of the antiviral agent (-)-oseltamivir phosphate is achieved using two aldol reactions as key steps.
PB  - Royal Soc Chemistry, Cambridge
T2  - Organic and Biomolecular Chemistry
T1  - An aldol approach to the enantioselective synthesis of (-)-oseltamivir phosphate
VL  - 9
IS  - 20
SP  - 6927
EP  - 6929
DO  - 10.1039/c1ob06248d
ER  - 

@article{
author = "Trajković, Milos and Ferjančić, Zorana and Saičić, Radomir",
year = "2011",
abstract = "A formal asymmetric synthesis of the antiviral agent (-)-oseltamivir phosphate is achieved using two aldol reactions as key steps.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Organic and Biomolecular Chemistry",
title = "An aldol approach to the enantioselective synthesis of (-)-oseltamivir phosphate",
volume = "9",
number = "20",
pages = "6927-6929",
doi = "10.1039/c1ob06248d"
}

Trajković, M., Ferjančić, Z.,& Saičić, R.. (2011). An aldol approach to the enantioselective synthesis of (-)-oseltamivir phosphate. in Organic and Biomolecular Chemistry
Royal Soc Chemistry, Cambridge., 9(20), 6927-6929.
https://doi.org/10.1039/c1ob06248d

Trajković M, Ferjančić Z, Saičić R. An aldol approach to the enantioselective synthesis of (-)-oseltamivir phosphate. in Organic and Biomolecular Chemistry. 2011;9(20):6927-6929.
doi:10.1039/c1ob06248d .

Trajković, Milos, Ferjančić, Zorana, Saičić, Radomir, "An aldol approach to the enantioselective synthesis of (-)-oseltamivir phosphate" in Organic and Biomolecular Chemistry, 9, no. 20 (2011):6927-6929,
https://doi.org/10.1039/c1ob06248d . .