TY  - JOUR
AU  - Opsenica, Igor
AU  - Smith, Kirsten K.
AU  - Gerena, Lucia
AU  - Gaica, Sandra
AU  - Šolaja, Bogdan A.
PY  - 2008
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/587
AB  - Several tetraoxane and 4-aminoquinoline molecules were prepared in order to examine the influence of ribofuranose as a carrier molecule on the antimalarial activity of test compounds. The synthesized compounds showed pronounced antimalarial activity against Plasmodium falciparum chloroquine susceptible D6, chloroquine resistant W2 and multidrug-resistant TM91C235 (Thailand) strains. The aminoquinoline derivative 4 was more active against W2 and TM91C235 strains than the control compounds (CQ and MFQ).
AB  - U ovom radu prikazana je sinteza nekoliko ribofuranozidnih tetraoksana i 4-aminohinolina u cilju sagledavanja odnosa struktura-aktivnost ove vrste antimalarika. Jedinjenja su pokazala izraženu antimalarijsku aktivnost prema hlorokin-osetljivom (D6), hlorokin-rezistentnom (W2) i višestruko rezistentnom (TM91C235 (Thailand)) soju Plasmodium falciparum. Aminohinolinski derivat 4 je aktivniji prema W2 i TM91C235 sojevima od kontrolnih jedinjenja (hlorokin i meflokin).
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Ribofuranose as a carrier of tetraoxane and 4-aminoquinoline antimalarial pharmacophores
T1  - Ribofuranoza kao nosač tetraoksanske i 4-aminohinolinske antimalarijske farmakofore
VL  - 73
IS  - 11
SP  - 1021
EP  - 1025
DO  - 10.2298/JSC0811021O
ER  - 

@article{
author = "Opsenica, Igor and Smith, Kirsten K. and Gerena, Lucia and Gaica, Sandra and Šolaja, Bogdan A.",
year = "2008",
abstract = "Several tetraoxane and 4-aminoquinoline molecules were prepared in order to examine the influence of ribofuranose as a carrier molecule on the antimalarial activity of test compounds. The synthesized compounds showed pronounced antimalarial activity against Plasmodium falciparum chloroquine susceptible D6, chloroquine resistant W2 and multidrug-resistant TM91C235 (Thailand) strains. The aminoquinoline derivative 4 was more active against W2 and TM91C235 strains than the control compounds (CQ and MFQ)., U ovom radu prikazana je sinteza nekoliko ribofuranozidnih tetraoksana i 4-aminohinolina u cilju sagledavanja odnosa struktura-aktivnost ove vrste antimalarika. Jedinjenja su pokazala izraženu antimalarijsku aktivnost prema hlorokin-osetljivom (D6), hlorokin-rezistentnom (W2) i višestruko rezistentnom (TM91C235 (Thailand)) soju Plasmodium falciparum. Aminohinolinski derivat 4 je aktivniji prema W2 i TM91C235 sojevima od kontrolnih jedinjenja (hlorokin i meflokin).",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Ribofuranose as a carrier of tetraoxane and 4-aminoquinoline antimalarial pharmacophores, Ribofuranoza kao nosač tetraoksanske i 4-aminohinolinske antimalarijske farmakofore",
volume = "73",
number = "11",
pages = "1021-1025",
doi = "10.2298/JSC0811021O"
}

Opsenica, I., Smith, K. K., Gerena, L., Gaica, S.,& Šolaja, B. A.. (2008). Ribofuranose as a carrier of tetraoxane and 4-aminoquinoline antimalarial pharmacophores. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 73(11), 1021-1025.
https://doi.org/10.2298/JSC0811021O

Opsenica I, Smith KK, Gerena L, Gaica S, Šolaja BA. Ribofuranose as a carrier of tetraoxane and 4-aminoquinoline antimalarial pharmacophores. in Journal of the Serbian Chemical Society. 2008;73(11):1021-1025.
doi:10.2298/JSC0811021O .

Opsenica, Igor, Smith, Kirsten K., Gerena, Lucia, Gaica, Sandra, Šolaja, Bogdan A., "Ribofuranose as a carrier of tetraoxane and 4-aminoquinoline antimalarial pharmacophores" in Journal of the Serbian Chemical Society, 73, no. 11 (2008):1021-1025,
https://doi.org/10.2298/JSC0811021O . .