TY  - JOUR
AU  - Sabo, Tibor
AU  - Dinovic, VA
AU  - Kaluđerović, Goran N.
AU  - Stanojković, Tatjana
AU  - Bogdanović, Goran A.
AU  - Juranic, ZD
PY  - 2005
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/693
AB  - Four platinum(IV) complexes, trans,trans-dichlorobis(N,N-dimethylglycinato)platinum(IV), trans,trans-[Pt(dmgly)(2)Cl-2] (1) and trans.trans-dibromobis(N,N'-dimethylglycinato)platinum(IV), trans,trans-[Pt(dmgly)(2)Br-2] (2), as well as, trans,trans-dichlorobis(N-methylglycinato)platinum(IV), trans,trans-[Pt(sar)(2)Cl-2] (3) and trans,trans-dibromobis(N-methylglycinato)platinum(IV), trans,trans-[Pt(sar)(2)Br-2] (4) (with configuration index for all complexes OC-6-14), were synthesized and characterized by elemental analysis, infrared and H-1 NMR spectroscopy. In the aim to assess the selectivity in the antitumor action of these complexes, the antiproliferative action of these compounds was determined to human adenocarcinoma HeLa cells; to human myelogenous leukemia K562 cells and to normal immunocompetent cells; i.e., on human PBMC. The details of the crystal structure synthesized trans,trans-[Pt(sar)(2)Br-2] complex were also reported here. In the crystal structure of trans, trans-[Pt(sar)(2)Br-2] the Pt(IV) ion had a deformed octahedral coordination with both N-methylglycinates and bromides bonded trans to one another and with the NPt-Br bond angles of 84.1(4) and 95.9(4)degrees. The trans, trans-[Pt(sar)(2)Br-2] complex molecules form 2D-layers with multiple N-H (...) O and C-H (...) O hydrogen bonds. (c) 2005 Elsevier B.V. All rights reserved.
PB  - Elsevier Science Sa, Lausanne
T2  - Inorganica Chimica Acta
T1  - Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC
VL  - 358
IS  - 7
SP  - 2239
EP  - 2245
DO  - 10.1016/j.ica.2005.01.007
ER  - 

@article{
author = "Sabo, Tibor and Dinovic, VA and Kaluđerović, Goran N. and Stanojković, Tatjana and Bogdanović, Goran A. and Juranic, ZD",
year = "2005",
abstract = "Four platinum(IV) complexes, trans,trans-dichlorobis(N,N-dimethylglycinato)platinum(IV), trans,trans-[Pt(dmgly)(2)Cl-2] (1) and trans.trans-dibromobis(N,N'-dimethylglycinato)platinum(IV), trans,trans-[Pt(dmgly)(2)Br-2] (2), as well as, trans,trans-dichlorobis(N-methylglycinato)platinum(IV), trans,trans-[Pt(sar)(2)Cl-2] (3) and trans,trans-dibromobis(N-methylglycinato)platinum(IV), trans,trans-[Pt(sar)(2)Br-2] (4) (with configuration index for all complexes OC-6-14), were synthesized and characterized by elemental analysis, infrared and H-1 NMR spectroscopy. In the aim to assess the selectivity in the antitumor action of these complexes, the antiproliferative action of these compounds was determined to human adenocarcinoma HeLa cells; to human myelogenous leukemia K562 cells and to normal immunocompetent cells; i.e., on human PBMC. The details of the crystal structure synthesized trans,trans-[Pt(sar)(2)Br-2] complex were also reported here. In the crystal structure of trans, trans-[Pt(sar)(2)Br-2] the Pt(IV) ion had a deformed octahedral coordination with both N-methylglycinates and bromides bonded trans to one another and with the NPt-Br bond angles of 84.1(4) and 95.9(4)degrees. The trans, trans-[Pt(sar)(2)Br-2] complex molecules form 2D-layers with multiple N-H (...) O and C-H (...) O hydrogen bonds. (c) 2005 Elsevier B.V. All rights reserved.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Inorganica Chimica Acta",
title = "Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC",
volume = "358",
number = "7",
pages = "2239-2245",
doi = "10.1016/j.ica.2005.01.007"
}

Sabo, T., Dinovic, V., Kaluđerović, G. N., Stanojković, T., Bogdanović, G. A.,& Juranic, Z.. (2005). Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC. in Inorganica Chimica Acta
Elsevier Science Sa, Lausanne., 358(7), 2239-2245.
https://doi.org/10.1016/j.ica.2005.01.007

Sabo T, Dinovic V, Kaluđerović GN, Stanojković T, Bogdanović GA, Juranic Z. Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC. in Inorganica Chimica Acta. 2005;358(7):2239-2245.
doi:10.1016/j.ica.2005.01.007 .

Sabo, Tibor, Dinovic, VA, Kaluđerović, Goran N., Stanojković, Tatjana, Bogdanović, Goran A., Juranic, ZD, "Syntheses and activity of some platinum(IV) complexes with N-methyl derivate of glycine and halogeno ligands against HeLa, K562 cell lines and human PBMC" in Inorganica Chimica Acta, 358, no. 7 (2005):2239-2245,
https://doi.org/10.1016/j.ica.2005.01.007 . .

TY  - JOUR
AU  - Kaluđerović, Goran N.
AU  - Dinovic, VM
AU  - Juranic, ZD
AU  - Stanojković, Tatjana
AU  - Sabo, Tibor
PY  - 2005
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/685
AB  - This paper reports on syntheses and characterization of chlorotribromo(O,O-n-butyl-ethylenediamine-N,N'-di-3-propanoate)platinum(IV) [II], dichlorodiiodo(O,O-ii-butyl-ethylenediamine-N,N'-di-3-propanoate)platinum(IV) [III], and dichloro(O,O-n-butyl-ethylenediamine-N,N'-di-3-propanoate)platinum(II) [V] complexes, with the formulae [Pt(dbeddp)Br3Cl], [Pt(dbeddp)Cl2I2] and [Pt(dbeddp)Cl-2], respectively. The complexes were characterized by elemental analysis, infrared, H-1 and C-13 NMR spectroscopy and electrospray mass spectrometry. In the aim to assess the selectivity in the antitumor action of these complexes, as well, as tetrachloro(O,O-n-butyl-ethylenediamine-N,N'-di-3-propanoate)platinum(IV) [I] and tetrachloro(O,O-n-pentyl-ethylenediamine-N,N'-di-3-propanoate)platinum(IV) [IV], the antiproliferative action of these compounds was determined to human adenocarcinoma HeLa cells, to human myelogenous leukemia K562 cells and to normal immunocompetent cells, i.e., on human peripheral blood mononuclear PBMC cells. (C) 2004 Elsevier Inc. All rights reserved.
PB  - Elsevier Science Inc, New York
T2  - Journal of Inorganic Biochemistry
T1  - Activity of some platinum(II/IV) complexes with O,O-n-butyl-and O,O-n-pentyl-ethylenediamine-N,N '-di-3-propanoate and halogeno ligands against HeLa and K562 cell lines and human PBMC
VL  - 99
IS  - 2
SP  - 488
EP  - 496
DO  - 10.1016/j.jinorgbio.2004.10.025
ER  - 

@article{
author = "Kaluđerović, Goran N. and Dinovic, VM and Juranic, ZD and Stanojković, Tatjana and Sabo, Tibor",
year = "2005",
abstract = "This paper reports on syntheses and characterization of chlorotribromo(O,O-n-butyl-ethylenediamine-N,N'-di-3-propanoate)platinum(IV) [II], dichlorodiiodo(O,O-ii-butyl-ethylenediamine-N,N'-di-3-propanoate)platinum(IV) [III], and dichloro(O,O-n-butyl-ethylenediamine-N,N'-di-3-propanoate)platinum(II) [V] complexes, with the formulae [Pt(dbeddp)Br3Cl], [Pt(dbeddp)Cl2I2] and [Pt(dbeddp)Cl-2], respectively. The complexes were characterized by elemental analysis, infrared, H-1 and C-13 NMR spectroscopy and electrospray mass spectrometry. In the aim to assess the selectivity in the antitumor action of these complexes, as well, as tetrachloro(O,O-n-butyl-ethylenediamine-N,N'-di-3-propanoate)platinum(IV) [I] and tetrachloro(O,O-n-pentyl-ethylenediamine-N,N'-di-3-propanoate)platinum(IV) [IV], the antiproliferative action of these compounds was determined to human adenocarcinoma HeLa cells, to human myelogenous leukemia K562 cells and to normal immunocompetent cells, i.e., on human peripheral blood mononuclear PBMC cells. (C) 2004 Elsevier Inc. All rights reserved.",
publisher = "Elsevier Science Inc, New York",
journal = "Journal of Inorganic Biochemistry",
title = "Activity of some platinum(II/IV) complexes with O,O-n-butyl-and O,O-n-pentyl-ethylenediamine-N,N '-di-3-propanoate and halogeno ligands against HeLa and K562 cell lines and human PBMC",
volume = "99",
number = "2",
pages = "488-496",
doi = "10.1016/j.jinorgbio.2004.10.025"
}

Kaluđerović, G. N., Dinovic, V., Juranic, Z., Stanojković, T.,& Sabo, T.. (2005). Activity of some platinum(II/IV) complexes with O,O-n-butyl-and O,O-n-pentyl-ethylenediamine-N,N '-di-3-propanoate and halogeno ligands against HeLa and K562 cell lines and human PBMC. in Journal of Inorganic Biochemistry
Elsevier Science Inc, New York., 99(2), 488-496.
https://doi.org/10.1016/j.jinorgbio.2004.10.025

Kaluđerović GN, Dinovic V, Juranic Z, Stanojković T, Sabo T. Activity of some platinum(II/IV) complexes with O,O-n-butyl-and O,O-n-pentyl-ethylenediamine-N,N '-di-3-propanoate and halogeno ligands against HeLa and K562 cell lines and human PBMC. in Journal of Inorganic Biochemistry. 2005;99(2):488-496.
doi:10.1016/j.jinorgbio.2004.10.025 .

Kaluđerović, Goran N., Dinovic, VM, Juranic, ZD, Stanojković, Tatjana, Sabo, Tibor, "Activity of some platinum(II/IV) complexes with O,O-n-butyl-and O,O-n-pentyl-ethylenediamine-N,N '-di-3-propanoate and halogeno ligands against HeLa and K562 cell lines and human PBMC" in Journal of Inorganic Biochemistry, 99, no. 2 (2005):488-496,
https://doi.org/10.1016/j.jinorgbio.2004.10.025 . .