TY  - JOUR
AU  - Stanković, Jovana
AU  - Gođevac, Dejan
AU  - Tešević, Vele
AU  - Dajić-Stevanović, Zora
AU  - Ćirić, Ana D.
AU  - Soković, Marina
AU  - Novaković, Miroslav M.
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3725
AB  - A new flavonoid glucoside derivative, patuletin 3-O-(2-O-feruloyl)-β-d-glucuronopyranosyl-(1→2)-β-d-glucopyranoside, named atriplexin IV (1), and three new triterpenoid saponin derivatives, two sulfonylated, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside-30-alolean-12-en-28-oate (2), named atriplexogenin I, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside)-30-hydroxyolean-12-en-28-oate (3), named atriplexogenin II, and β-d-glucopyranosyl-3-O-(β-d-glucopyranosyl-(1→2)-β-d-galactopyranosyl-(1→2)-α-l-arabinopyranoside)-30-alolean-12-en-28-oate (4), named atriplexogenin III, were isolated by silica gel column and semipreparative HPLC chromatography from the n-butanol extract of the salt marsh plant Atriplex tatarica. In addition, two known secondary metabolites, patuletin3-O-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (5) and patuletin 3-O-5'-O-feruloyl-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (6), were isolated for the first time from A. tatarica. The structures of the isolated compounds were elucidated by 1D and 2D NMR, HRESIMS, IR, and UV data. Antibacterial activity by the microdilution method and antibiofilm activity against P. aeruginosa were assessed. Compound 5 possesses significant antibacterial activity, while the most potent antibiofilm agent is compound 2.
PB  - American Chemical Society
T2  - Journal of Natural Products
T1  - Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa
VL  - 82
IS  - 6
SP  - 1487
EP  - 1495
DO  - 10.1021/acs.jnatprod.8b00970
ER  - 

@article{
author = "Stanković, Jovana and Gođevac, Dejan and Tešević, Vele and Dajić-Stevanović, Zora and Ćirić, Ana D. and Soković, Marina and Novaković, Miroslav M.",
year = "2019",
abstract = "A new flavonoid glucoside derivative, patuletin 3-O-(2-O-feruloyl)-β-d-glucuronopyranosyl-(1→2)-β-d-glucopyranoside, named atriplexin IV (1), and three new triterpenoid saponin derivatives, two sulfonylated, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside-30-alolean-12-en-28-oate (2), named atriplexogenin I, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside)-30-hydroxyolean-12-en-28-oate (3), named atriplexogenin II, and β-d-glucopyranosyl-3-O-(β-d-glucopyranosyl-(1→2)-β-d-galactopyranosyl-(1→2)-α-l-arabinopyranoside)-30-alolean-12-en-28-oate (4), named atriplexogenin III, were isolated by silica gel column and semipreparative HPLC chromatography from the n-butanol extract of the salt marsh plant Atriplex tatarica. In addition, two known secondary metabolites, patuletin3-O-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (5) and patuletin 3-O-5'-O-feruloyl-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (6), were isolated for the first time from A. tatarica. The structures of the isolated compounds were elucidated by 1D and 2D NMR, HRESIMS, IR, and UV data. Antibacterial activity by the microdilution method and antibiofilm activity against P. aeruginosa were assessed. Compound 5 possesses significant antibacterial activity, while the most potent antibiofilm agent is compound 2.",
publisher = "American Chemical Society",
journal = "Journal of Natural Products",
title = "Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa",
volume = "82",
number = "6",
pages = "1487-1495",
doi = "10.1021/acs.jnatprod.8b00970"
}

Stanković, J., Gođevac, D., Tešević, V., Dajić-Stevanović, Z., Ćirić, A. D., Soković, M.,& Novaković, M. M.. (2019). Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. in Journal of Natural Products
American Chemical Society., 82(6), 1487-1495.
https://doi.org/10.1021/acs.jnatprod.8b00970

Stanković J, Gođevac D, Tešević V, Dajić-Stevanović Z, Ćirić AD, Soković M, Novaković MM. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. in Journal of Natural Products. 2019;82(6):1487-1495.
doi:10.1021/acs.jnatprod.8b00970 .

Stanković, Jovana, Gođevac, Dejan, Tešević, Vele, Dajić-Stevanović, Zora, Ćirić, Ana D., Soković, Marina, Novaković, Miroslav M., "Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa" in Journal of Natural Products, 82, no. 6 (2019):1487-1495,
https://doi.org/10.1021/acs.jnatprod.8b00970 . .

TY  - DATA
AU  - Stanković, Jovana
AU  - Gođevac, Dejan
AU  - Tešević, Vele
AU  - Dajić-Stevanović, Zora
AU  - Ćirić, Ana D.
AU  - Soković, Marina
AU  - Novaković, Miroslav M.
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3726
PB  - American Chemical Society
T2  - Journal of Natural Products
T1  - Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3726
ER  - 

@misc{
author = "Stanković, Jovana and Gođevac, Dejan and Tešević, Vele and Dajić-Stevanović, Zora and Ćirić, Ana D. and Soković, Marina and Novaković, Miroslav M.",
year = "2019",
publisher = "American Chemical Society",
journal = "Journal of Natural Products",
title = "Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3726"
}

Stanković, J., Gođevac, D., Tešević, V., Dajić-Stevanović, Z., Ćirić, A. D., Soković, M.,& Novaković, M. M.. (2019). Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970. in Journal of Natural Products
American Chemical Society..
https://hdl.handle.net/21.15107/rcub_cherry_3726

Stanković J, Gođevac D, Tešević V, Dajić-Stevanović Z, Ćirić AD, Soković M, Novaković MM. Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970. in Journal of Natural Products. 2019;.
https://hdl.handle.net/21.15107/rcub_cherry_3726 .

Stanković, Jovana, Gođevac, Dejan, Tešević, Vele, Dajić-Stevanović, Zora, Ćirić, Ana D., Soković, Marina, Novaković, Miroslav M., "Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970" in Journal of Natural Products (2019),
https://hdl.handle.net/21.15107/rcub_cherry_3726 .

TY  - JOUR
AU  - Božunović, Jelena
AU  - Živković, Suzana
AU  - Gašić, Uroš M.
AU  - Glamočlija, Jasmina
AU  - Ćirić, Ana D.
AU  - Matekalo, Dragana
AU  - Šiler, Branislav
AU  - Soković, Marina
AU  - Tešić, Živoslav Lj.
AU  - Mišić, Danijela
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2579
AB  - The present study was principally aimed at ascertaining the differences in metabolomics profiles and biological activities between non-hydrolyzed (ME) and hydrolyzed methanol extract (HME) of Centaurium erythraea Rafn. UHPLC-MS/MS Orbitrap analysis showed that the enzymatic hydrolysis of the extract caused changes in beta-Dglycoside/aglycone ratio of both flavonoid and secoiridoid compounds. UHPLC/DAD/ + HESI - qqqMS characterization and/or quantification of secoiridoid glucosides (SGs) and their aglycones in both ME and HME revealed gentiopicral and erythrocentaurin as the major aglycones, the same metabolic products which appear after the hydrolysis of pure swertiamarin, the dominant secoiridoid glucoside of C. erythraea. SGs played an antioxidant role only in ABTS assay, whilst the remarkable antioxidant potential of C. erythraea methanol extract is ascribed chiefly to phenolics detected in it. Interestingly, antioxidant activities of swertiamarin and sweroside recorded in ABTS assay increased after the compounds have been hydrolyzed, which highlighted their possible antioxidant role during ingestion. Strong antimicrobial activities of ME and HME against a vast array of pathogens, which exceed the effects of the reference antibiotics and antimycotics, largely depended on the amount of secoiridoids in either of the glycosylation forms. Extracts and pure secoiridoids were especially effective against most of the tested Penicillium species. On the other hand, P. funiculosum has evolved an efficient mechanism of detoxification of sub-lethal concentrations of secoiridoid glucosides, involving their biotransformation and complete digestion. The presented findings will contribute to clarify the fate and role of the SGs after C. erythraea ingestion within in vivo systems, and to further promote this remarkable plant as a food preservation additive with significant health benefits.
PB  - Elsevier Science Bv, Amsterdam
T2  - Industrial Crops and Products
T1  - In vitro and in vivo transformations of Centaurium erythraea secoiridoid glucosides alternate their antioxidant and antimicrobial capacity
VL  - 111
SP  - 705
EP  - 721
DO  - 10.1016/j.indcrop.2017.11.040
ER  - 

@article{
author = "Božunović, Jelena and Živković, Suzana and Gašić, Uroš M. and Glamočlija, Jasmina and Ćirić, Ana D. and Matekalo, Dragana and Šiler, Branislav and Soković, Marina and Tešić, Živoslav Lj. and Mišić, Danijela",
year = "2018",
abstract = "The present study was principally aimed at ascertaining the differences in metabolomics profiles and biological activities between non-hydrolyzed (ME) and hydrolyzed methanol extract (HME) of Centaurium erythraea Rafn. UHPLC-MS/MS Orbitrap analysis showed that the enzymatic hydrolysis of the extract caused changes in beta-Dglycoside/aglycone ratio of both flavonoid and secoiridoid compounds. UHPLC/DAD/ + HESI - qqqMS characterization and/or quantification of secoiridoid glucosides (SGs) and their aglycones in both ME and HME revealed gentiopicral and erythrocentaurin as the major aglycones, the same metabolic products which appear after the hydrolysis of pure swertiamarin, the dominant secoiridoid glucoside of C. erythraea. SGs played an antioxidant role only in ABTS assay, whilst the remarkable antioxidant potential of C. erythraea methanol extract is ascribed chiefly to phenolics detected in it. Interestingly, antioxidant activities of swertiamarin and sweroside recorded in ABTS assay increased after the compounds have been hydrolyzed, which highlighted their possible antioxidant role during ingestion. Strong antimicrobial activities of ME and HME against a vast array of pathogens, which exceed the effects of the reference antibiotics and antimycotics, largely depended on the amount of secoiridoids in either of the glycosylation forms. Extracts and pure secoiridoids were especially effective against most of the tested Penicillium species. On the other hand, P. funiculosum has evolved an efficient mechanism of detoxification of sub-lethal concentrations of secoiridoid glucosides, involving their biotransformation and complete digestion. The presented findings will contribute to clarify the fate and role of the SGs after C. erythraea ingestion within in vivo systems, and to further promote this remarkable plant as a food preservation additive with significant health benefits.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Industrial Crops and Products",
title = "In vitro and in vivo transformations of Centaurium erythraea secoiridoid glucosides alternate their antioxidant and antimicrobial capacity",
volume = "111",
pages = "705-721",
doi = "10.1016/j.indcrop.2017.11.040"
}

Božunović, J., Živković, S., Gašić, U. M., Glamočlija, J., Ćirić, A. D., Matekalo, D., Šiler, B., Soković, M., Tešić, Ž. Lj.,& Mišić, D.. (2018). In vitro and in vivo transformations of Centaurium erythraea secoiridoid glucosides alternate their antioxidant and antimicrobial capacity. in Industrial Crops and Products
Elsevier Science Bv, Amsterdam., 111, 705-721.
https://doi.org/10.1016/j.indcrop.2017.11.040

Božunović J, Živković S, Gašić UM, Glamočlija J, Ćirić AD, Matekalo D, Šiler B, Soković M, Tešić ŽL, Mišić D. In vitro and in vivo transformations of Centaurium erythraea secoiridoid glucosides alternate their antioxidant and antimicrobial capacity. in Industrial Crops and Products. 2018;111:705-721.
doi:10.1016/j.indcrop.2017.11.040 .

Božunović, Jelena, Živković, Suzana, Gašić, Uroš M., Glamočlija, Jasmina, Ćirić, Ana D., Matekalo, Dragana, Šiler, Branislav, Soković, Marina, Tešić, Živoslav Lj., Mišić, Danijela, "In vitro and in vivo transformations of Centaurium erythraea secoiridoid glucosides alternate their antioxidant and antimicrobial capacity" in Industrial Crops and Products, 111 (2018):705-721,
https://doi.org/10.1016/j.indcrop.2017.11.040 . .

TY  - DATA
AU  - Božunović, Jelena
AU  - Živković, Suzana
AU  - Gašić, Uroš M.
AU  - Glamočlija, Jasmina
AU  - Ćirić, Ana D.
AU  - Matekalo, Dragana
AU  - Šiler, Branislav
AU  - Soković, Marina
AU  - Tešić, Živoslav Lj.
AU  - Mišić, Danijela
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3208
PB  - Elsevier Science Bv, Amsterdam
T2  - Industrial Crops and Products
T1  - Supplementary material for the article: Božunović, J.; Živković, S.; Gašić, U.; Glamočlija, J.; Ćirić, A.; Matekalo, D.; Šiler, B.; Soković, M.; Tešić, Ž.; Mišić, D. In Vitro and in Vivo Transformations of Centaurium Erythraea Secoiridoid Glucosides Alternate Their Antioxidant and Antimicrobial Capacity. Industrial Crops and Products 2018, 111, 705–721. https://doi.org/10.1016/j.indcrop.2017.11.040
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3208
ER  - 

@misc{
author = "Božunović, Jelena and Živković, Suzana and Gašić, Uroš M. and Glamočlija, Jasmina and Ćirić, Ana D. and Matekalo, Dragana and Šiler, Branislav and Soković, Marina and Tešić, Živoslav Lj. and Mišić, Danijela",
year = "2018",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Industrial Crops and Products",
title = "Supplementary material for the article: Božunović, J.; Živković, S.; Gašić, U.; Glamočlija, J.; Ćirić, A.; Matekalo, D.; Šiler, B.; Soković, M.; Tešić, Ž.; Mišić, D. In Vitro and in Vivo Transformations of Centaurium Erythraea Secoiridoid Glucosides Alternate Their Antioxidant and Antimicrobial Capacity. Industrial Crops and Products 2018, 111, 705–721. https://doi.org/10.1016/j.indcrop.2017.11.040",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3208"
}

Božunović, J., Živković, S., Gašić, U. M., Glamočlija, J., Ćirić, A. D., Matekalo, D., Šiler, B., Soković, M., Tešić, Ž. Lj.,& Mišić, D.. (2018). Supplementary material for the article: Božunović, J.; Živković, S.; Gašić, U.; Glamočlija, J.; Ćirić, A.; Matekalo, D.; Šiler, B.; Soković, M.; Tešić, Ž.; Mišić, D. In Vitro and in Vivo Transformations of Centaurium Erythraea Secoiridoid Glucosides Alternate Their Antioxidant and Antimicrobial Capacity. Industrial Crops and Products 2018, 111, 705–721. https://doi.org/10.1016/j.indcrop.2017.11.040. in Industrial Crops and Products
Elsevier Science Bv, Amsterdam..
https://hdl.handle.net/21.15107/rcub_cherry_3208

Božunović J, Živković S, Gašić UM, Glamočlija J, Ćirić AD, Matekalo D, Šiler B, Soković M, Tešić ŽL, Mišić D. Supplementary material for the article: Božunović, J.; Živković, S.; Gašić, U.; Glamočlija, J.; Ćirić, A.; Matekalo, D.; Šiler, B.; Soković, M.; Tešić, Ž.; Mišić, D. In Vitro and in Vivo Transformations of Centaurium Erythraea Secoiridoid Glucosides Alternate Their Antioxidant and Antimicrobial Capacity. Industrial Crops and Products 2018, 111, 705–721. https://doi.org/10.1016/j.indcrop.2017.11.040. in Industrial Crops and Products. 2018;.
https://hdl.handle.net/21.15107/rcub_cherry_3208 .

Božunović, Jelena, Živković, Suzana, Gašić, Uroš M., Glamočlija, Jasmina, Ćirić, Ana D., Matekalo, Dragana, Šiler, Branislav, Soković, Marina, Tešić, Živoslav Lj., Mišić, Danijela, "Supplementary material for the article: Božunović, J.; Živković, S.; Gašić, U.; Glamočlija, J.; Ćirić, A.; Matekalo, D.; Šiler, B.; Soković, M.; Tešić, Ž.; Mišić, D. In Vitro and in Vivo Transformations of Centaurium Erythraea Secoiridoid Glucosides Alternate Their Antioxidant and Antimicrobial Capacity. Industrial Crops and Products 2018, 111, 705–721. https://doi.org/10.1016/j.indcrop.2017.11.040" in Industrial Crops and Products (2018),
https://hdl.handle.net/21.15107/rcub_cherry_3208 .

TY  - JOUR
AU  - Nenadic, Marija
AU  - Soković, Marina
AU  - Glamočlija, Jasmina
AU  - Ćirić, Ana D.
AU  - Peric-Mataruga, Vesna
AU  - Ilijin, Larisa
AU  - Tešević, Vele
AU  - Todosijević, Marina
AU  - Vujisić, Ljubodrag V.
AU  - Vesović, Nikola
AU  - Ćurčić, Srećko
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2381
AB  - Recently, various insect secretions have been tested as possible antimicrobial agents. In beetles, these secretions are essentially products of various exocrine glands, of which particular emphasis is on pygidial glands that are common for the suborder Adephaga. The antimicrobial potential of the pygidial gland secretion isolated from the adults of Calosoma sycophanta against human pathogens has been tested and compared with the potential of other carabid species, particularly within the tribe Carabini. The antimicrobial assay includes a microdilution method which was applied in order to determine the minimal inhibitory, minimal fungicidal and minimal bactericidal concentrations. It has been tested the effect of the secretion against eight strains of fungal and eight strains of bacterial species. The secretion sample of the tested carabid species has shown statistically significant antifungal effect against all strains of treated micromycetes, the highest in comparison with previously tested carabids (Carabus spp., Laemostenus punctatus and Abax parallelepipedus). Aspergillus versicolor proved to be the most sensitive micromycete, while the remaining seven fungal strains have shown the same level of sensibility. In comparison with commercial mycotics ketoconazole and bifonazole, applied as positive controls, the tested secretion showed much higher antifungal activity for all fungal strains. Antibacterial effect has been manifested only against one bacterial strain (Escherichia coli), contrary to other previously studied carabid species. These observations might have a significant impact on the ecological domain and possible purpose in biomedical studies and applications in the future. Additionally, morpho-histology of the pygidial glands of C. sycophanta is investigated and discussed.
PB  - Springer, New York
T2  - Applied Microbiology and Biotechnology
T1  - The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens
VL  - 101
IS  - 3
SP  - 977
EP  - 985
DO  - 10.1007/s00253-016-8082-7
ER  - 

@article{
author = "Nenadic, Marija and Soković, Marina and Glamočlija, Jasmina and Ćirić, Ana D. and Peric-Mataruga, Vesna and Ilijin, Larisa and Tešević, Vele and Todosijević, Marina and Vujisić, Ljubodrag V. and Vesović, Nikola and Ćurčić, Srećko",
year = "2017",
abstract = "Recently, various insect secretions have been tested as possible antimicrobial agents. In beetles, these secretions are essentially products of various exocrine glands, of which particular emphasis is on pygidial glands that are common for the suborder Adephaga. The antimicrobial potential of the pygidial gland secretion isolated from the adults of Calosoma sycophanta against human pathogens has been tested and compared with the potential of other carabid species, particularly within the tribe Carabini. The antimicrobial assay includes a microdilution method which was applied in order to determine the minimal inhibitory, minimal fungicidal and minimal bactericidal concentrations. It has been tested the effect of the secretion against eight strains of fungal and eight strains of bacterial species. The secretion sample of the tested carabid species has shown statistically significant antifungal effect against all strains of treated micromycetes, the highest in comparison with previously tested carabids (Carabus spp., Laemostenus punctatus and Abax parallelepipedus). Aspergillus versicolor proved to be the most sensitive micromycete, while the remaining seven fungal strains have shown the same level of sensibility. In comparison with commercial mycotics ketoconazole and bifonazole, applied as positive controls, the tested secretion showed much higher antifungal activity for all fungal strains. Antibacterial effect has been manifested only against one bacterial strain (Escherichia coli), contrary to other previously studied carabid species. These observations might have a significant impact on the ecological domain and possible purpose in biomedical studies and applications in the future. Additionally, morpho-histology of the pygidial glands of C. sycophanta is investigated and discussed.",
publisher = "Springer, New York",
journal = "Applied Microbiology and Biotechnology",
title = "The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens",
volume = "101",
number = "3",
pages = "977-985",
doi = "10.1007/s00253-016-8082-7"
}

Nenadic, M., Soković, M., Glamočlija, J., Ćirić, A. D., Peric-Mataruga, V., Ilijin, L., Tešević, V., Todosijević, M., Vujisić, L. V., Vesović, N.,& Ćurčić, S.. (2017). The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens. in Applied Microbiology and Biotechnology
Springer, New York., 101(3), 977-985.
https://doi.org/10.1007/s00253-016-8082-7

Nenadic M, Soković M, Glamočlija J, Ćirić AD, Peric-Mataruga V, Ilijin L, Tešević V, Todosijević M, Vujisić LV, Vesović N, Ćurčić S. The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens. in Applied Microbiology and Biotechnology. 2017;101(3):977-985.
doi:10.1007/s00253-016-8082-7 .

Nenadic, Marija, Soković, Marina, Glamočlija, Jasmina, Ćirić, Ana D., Peric-Mataruga, Vesna, Ilijin, Larisa, Tešević, Vele, Todosijević, Marina, Vujisić, Ljubodrag V., Vesović, Nikola, Ćurčić, Srećko, "The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens" in Applied Microbiology and Biotechnology, 101, no. 3 (2017):977-985,
https://doi.org/10.1007/s00253-016-8082-7 . .

TY  - JOUR
AU  - Nenadic, Marija
AU  - Ljaljević-Grbić, Milica
AU  - Stupar, Miloš
AU  - Vukojević, Jelena
AU  - Ćirić, Ana D.
AU  - Tešević, Vele
AU  - Vujisić, Ljubodrag V.
AU  - Todosijević, Marina
AU  - Vesović, Nikola
AU  - Živković, Nemanja
AU  - Ćurčić, Srećko
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2474
AB  - The antifungal potential of the pygidial gland secretion of the troglophilic ground beetle Laemostenus punctatus from a cave in Southeastern Serbia against cave-dwelling micromycetes, isolated from the same habitat, has been investigated. Eleven collected samples were analyzed and 32 isolates of cave-dwelling fungi were documented. A total of 14 fungal species were identified as members of the genera Aspergillus, Penicillium, Alternaria, Cladosporium, Rhizopus, Trichoderma, Arthrinium, Aureobasidium, Epicoccum, Talaromyces, and Fusarium. Five isolates were selected for testing the antifungal activity of the pygidial gland secretion : Talaromyces duclauxi, Aspergillus brunneouniseriatus, Penicillium sp., Rhizopus stolonifer, and Trichoderma viride. The microdilution method has been applied to detect minimal inhibitory concentrations (MICs) and minimal fungicidal concentrations (MFCs). The most sensitive isolate was Penicillium sp., while the other isolates demonstrated a high level of resistance to the tested agent. L. punctatus has developed a special mechanism of producing specific compounds that act synergistically within the secretion mixture, which are responsible for the antifungal action against pathogens from the cave. The results open opportunities for further research in the field of ground beetle defense against pathogens, which could have an important application in human medicine, in addition to the environmental impact, primarily.
PB  - Springer Heidelberg, Heidelberg
T2  - Naturwissenschaften
T1  - Antifungal activity of the pygidial gland secretion of Laemostenus punctatus (Coleoptera: Carabidae) against cave-dwelling micromycetes
VL  - 104
IS  - 5-6
SP  - 52
DO  - 10.1007/s00114-017-1474-4
ER  - 

@article{
author = "Nenadic, Marija and Ljaljević-Grbić, Milica and Stupar, Miloš and Vukojević, Jelena and Ćirić, Ana D. and Tešević, Vele and Vujisić, Ljubodrag V. and Todosijević, Marina and Vesović, Nikola and Živković, Nemanja and Ćurčić, Srećko",
year = "2017",
abstract = "The antifungal potential of the pygidial gland secretion of the troglophilic ground beetle Laemostenus punctatus from a cave in Southeastern Serbia against cave-dwelling micromycetes, isolated from the same habitat, has been investigated. Eleven collected samples were analyzed and 32 isolates of cave-dwelling fungi were documented. A total of 14 fungal species were identified as members of the genera Aspergillus, Penicillium, Alternaria, Cladosporium, Rhizopus, Trichoderma, Arthrinium, Aureobasidium, Epicoccum, Talaromyces, and Fusarium. Five isolates were selected for testing the antifungal activity of the pygidial gland secretion : Talaromyces duclauxi, Aspergillus brunneouniseriatus, Penicillium sp., Rhizopus stolonifer, and Trichoderma viride. The microdilution method has been applied to detect minimal inhibitory concentrations (MICs) and minimal fungicidal concentrations (MFCs). The most sensitive isolate was Penicillium sp., while the other isolates demonstrated a high level of resistance to the tested agent. L. punctatus has developed a special mechanism of producing specific compounds that act synergistically within the secretion mixture, which are responsible for the antifungal action against pathogens from the cave. The results open opportunities for further research in the field of ground beetle defense against pathogens, which could have an important application in human medicine, in addition to the environmental impact, primarily.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Naturwissenschaften",
title = "Antifungal activity of the pygidial gland secretion of Laemostenus punctatus (Coleoptera: Carabidae) against cave-dwelling micromycetes",
volume = "104",
number = "5-6",
pages = "52",
doi = "10.1007/s00114-017-1474-4"
}

Nenadic, M., Ljaljević-Grbić, M., Stupar, M., Vukojević, J., Ćirić, A. D., Tešević, V., Vujisić, L. V., Todosijević, M., Vesović, N., Živković, N.,& Ćurčić, S.. (2017). Antifungal activity of the pygidial gland secretion of Laemostenus punctatus (Coleoptera: Carabidae) against cave-dwelling micromycetes. in Naturwissenschaften
Springer Heidelberg, Heidelberg., 104(5-6), 52.
https://doi.org/10.1007/s00114-017-1474-4

Nenadic M, Ljaljević-Grbić M, Stupar M, Vukojević J, Ćirić AD, Tešević V, Vujisić LV, Todosijević M, Vesović N, Živković N, Ćurčić S. Antifungal activity of the pygidial gland secretion of Laemostenus punctatus (Coleoptera: Carabidae) against cave-dwelling micromycetes. in Naturwissenschaften. 2017;104(5-6):52.
doi:10.1007/s00114-017-1474-4 .

Nenadic, Marija, Ljaljević-Grbić, Milica, Stupar, Miloš, Vukojević, Jelena, Ćirić, Ana D., Tešević, Vele, Vujisić, Ljubodrag V., Todosijević, Marina, Vesović, Nikola, Živković, Nemanja, Ćurčić, Srećko, "Antifungal activity of the pygidial gland secretion of Laemostenus punctatus (Coleoptera: Carabidae) against cave-dwelling micromycetes" in Naturwissenschaften, 104, no. 5-6 (2017):52,
https://doi.org/10.1007/s00114-017-1474-4 . .

TY  - JOUR
AU  - Ilic-Tomić, Tatjana
AU  - Soković, Marina
AU  - Vojnović, Sandra
AU  - Ćirić, Ana D.
AU  - Veljić, Milan
AU  - Nikodinović-Runić, Jasmina
AU  - Novaković, Miroslav M.
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2395
AB  - Diarylheptanoids from the barks of Alnus viridis ssp. viridis (green alder) and Alnus glutinosa (black alder) were explored for anti-quorum sensing activity. Chemicals with anti-quorum sensing activity have recently been examined for antimicrobial applications. The anti-quorum sensing activity of the selected diarylheptanoids was determined using two biosensors, namely Pseudomonas aeruginosa PAO1 and Chromobacterium violaceum CV026. Although all of the investigated compounds negatively influenced the motility of P. aeruginosa PAO1, four were able to inhibit biofilm formation of this human opportunistic pathogen for 40-70%. Three of the diarylheptanoids (3, 4, and 5) negatively influenced the biosynthesis of pyocyanin, which is under the control of quorum sensing. Platyphyllenone (7) and hirsutenone (5) were able to inhibit the biosynthesis of violacein in C. violaceum CV026, with 5 being able to inhibit the synthesis of both biopigments. Only one of the tested diarylheptanoids (1) was shown to significantly decrease the production of acyl homoserine lactones (AHL) in P. aeruginosa PAO1, more specifically, production of the long chain N-(3-oxododecanoyl)- l-HSL. On the other side, four diarylheptanoids (2-5) significantly reduced the synthesis of 2-alkyl-4-quinolones, part of the P. aeruginosa quinolone-mediated signaling system. To properly assess therapeutic potential of these compounds, their in vitro antiproliferative effect on normal human lung fibroblasts was determined, with doses affecting cell proliferation between 10 and 100 mu g/mL. This study confirms that the barks of green and black alders are rich source of phytochemicals with a wide range of biological activities that could further be exploited as natural agents against bacterial contaminations and infections.
PB  - Georg Thieme Verlag Kg, Stuttgart
T2  - Planta Medica
T1  - Diarylheptanoids from Alnus viridis ssp viridis and Alnus glutinosa: Modulation of Quorum Sensing Activity in Pseudomonas aeruginosa
VL  - 83
IS  - 01-02
SP  - 117
EP  - 125
DO  - 10.1055/s-0042-107674
ER  - 

@article{
author = "Ilic-Tomić, Tatjana and Soković, Marina and Vojnović, Sandra and Ćirić, Ana D. and Veljić, Milan and Nikodinović-Runić, Jasmina and Novaković, Miroslav M.",
year = "2017",
abstract = "Diarylheptanoids from the barks of Alnus viridis ssp. viridis (green alder) and Alnus glutinosa (black alder) were explored for anti-quorum sensing activity. Chemicals with anti-quorum sensing activity have recently been examined for antimicrobial applications. The anti-quorum sensing activity of the selected diarylheptanoids was determined using two biosensors, namely Pseudomonas aeruginosa PAO1 and Chromobacterium violaceum CV026. Although all of the investigated compounds negatively influenced the motility of P. aeruginosa PAO1, four were able to inhibit biofilm formation of this human opportunistic pathogen for 40-70%. Three of the diarylheptanoids (3, 4, and 5) negatively influenced the biosynthesis of pyocyanin, which is under the control of quorum sensing. Platyphyllenone (7) and hirsutenone (5) were able to inhibit the biosynthesis of violacein in C. violaceum CV026, with 5 being able to inhibit the synthesis of both biopigments. Only one of the tested diarylheptanoids (1) was shown to significantly decrease the production of acyl homoserine lactones (AHL) in P. aeruginosa PAO1, more specifically, production of the long chain N-(3-oxododecanoyl)- l-HSL. On the other side, four diarylheptanoids (2-5) significantly reduced the synthesis of 2-alkyl-4-quinolones, part of the P. aeruginosa quinolone-mediated signaling system. To properly assess therapeutic potential of these compounds, their in vitro antiproliferative effect on normal human lung fibroblasts was determined, with doses affecting cell proliferation between 10 and 100 mu g/mL. This study confirms that the barks of green and black alders are rich source of phytochemicals with a wide range of biological activities that could further be exploited as natural agents against bacterial contaminations and infections.",
publisher = "Georg Thieme Verlag Kg, Stuttgart",
journal = "Planta Medica",
title = "Diarylheptanoids from Alnus viridis ssp viridis and Alnus glutinosa: Modulation of Quorum Sensing Activity in Pseudomonas aeruginosa",
volume = "83",
number = "01-02",
pages = "117-125",
doi = "10.1055/s-0042-107674"
}

Ilic-Tomić, T., Soković, M., Vojnović, S., Ćirić, A. D., Veljić, M., Nikodinović-Runić, J.,& Novaković, M. M.. (2017). Diarylheptanoids from Alnus viridis ssp viridis and Alnus glutinosa: Modulation of Quorum Sensing Activity in Pseudomonas aeruginosa. in Planta Medica
Georg Thieme Verlag Kg, Stuttgart., 83(01-02), 117-125.
https://doi.org/10.1055/s-0042-107674

Ilic-Tomić T, Soković M, Vojnović S, Ćirić AD, Veljić M, Nikodinović-Runić J, Novaković MM. Diarylheptanoids from Alnus viridis ssp viridis and Alnus glutinosa: Modulation of Quorum Sensing Activity in Pseudomonas aeruginosa. in Planta Medica. 2017;83(01-02):117-125.
doi:10.1055/s-0042-107674 .

Ilic-Tomić, Tatjana, Soković, Marina, Vojnović, Sandra, Ćirić, Ana D., Veljić, Milan, Nikodinović-Runić, Jasmina, Novaković, Miroslav M., "Diarylheptanoids from Alnus viridis ssp viridis and Alnus glutinosa: Modulation of Quorum Sensing Activity in Pseudomonas aeruginosa" in Planta Medica, 83, no. 01-02 (2017):117-125,
https://doi.org/10.1055/s-0042-107674 . .

TY  - JOUR
AU  - Nenadic, Marija
AU  - Soković, Marina
AU  - Glamočlija, Jasmina
AU  - Ćirić, Ana D.
AU  - Peric-Mataruga, Vesna
AU  - Ilijin, Larisa
AU  - Tešević, Vele
AU  - Vujisić, Ljubodrag V.
AU  - Todosijević, Marina
AU  - Vesović, Nikola
AU  - Ćurčić, Srećko
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1904
AB  - The antimicrobial properties of the pygidial gland secretions released by the adults of the three ground beetle species, Carabus ullrichii, C. coriaceus, and Abax parallelepipedus, have been tested. Microdilution method was applied for detection of minimal inhibitory concentrations (MICs), minimal bactericidal concentrations (MBCs), and minimal fungicidal concentrations (MFCs). Additionally, morpho-histology of the pygidial glands is investigated. We have tested 16 laboratory and clinical strains of human pathogens-eight bacterial both gram-positive and gram-negative species and eight fungal species. The pygidial secretion samples of C. ullrichii have showed the strongest antimicrobial effect against all strains of treated bacteria and fungi. Staphylococcus aureus, Lysteria monocytogenes, and Salmonella typhimurium proved to be the most sensitive bacterial strains. Penicillium funiculosum proved to be the most sensitive micromycete, while P. ochrochloron and P. verrucosum var. cyclopium the most resistant micromycetes. The pygidial secretion of C. coriaceus has showed antibacterial potential solely against Pseudomonas aeruginosa and antifungal activity against Aspergillus fumigatus, A. versicolor, A. ochraceus, and P. ochrochloron. Antibacterial properties of pygidial gland secretion of A. parallelepipedus were achieved against P. aeruginosa, while antifungal activity was detected against five of the eight tested micromycetes (A. fumigatus, A. versicolor, A. ochraceus, Trichoderma viride, and P. verrucosum var. cyclopium). Commercial antibiotics Streptomycin and Ampicillin and mycotics Ketoconazole and Bifonazole, applied as the positive controls, showed higher antibacterial/antifungal properties for all bacterial and fungal strains. The results of this observation might have a significant impact on the environmental aspects and possible medical purpose in the future.
PB  - Springer Heidelberg, Heidelberg
T2  - Naturwissenschaften
T1  - Antimicrobial activity of the pygidial gland secretion of three ground beetle species (Insecta: Coleoptera: Carabidae)
VL  - 103
IS  - 3-4
SP  - 34
DO  - 10.1007/s00114-016-1358-z
ER  - 

@article{
author = "Nenadic, Marija and Soković, Marina and Glamočlija, Jasmina and Ćirić, Ana D. and Peric-Mataruga, Vesna and Ilijin, Larisa and Tešević, Vele and Vujisić, Ljubodrag V. and Todosijević, Marina and Vesović, Nikola and Ćurčić, Srećko",
year = "2016",
abstract = "The antimicrobial properties of the pygidial gland secretions released by the adults of the three ground beetle species, Carabus ullrichii, C. coriaceus, and Abax parallelepipedus, have been tested. Microdilution method was applied for detection of minimal inhibitory concentrations (MICs), minimal bactericidal concentrations (MBCs), and minimal fungicidal concentrations (MFCs). Additionally, morpho-histology of the pygidial glands is investigated. We have tested 16 laboratory and clinical strains of human pathogens-eight bacterial both gram-positive and gram-negative species and eight fungal species. The pygidial secretion samples of C. ullrichii have showed the strongest antimicrobial effect against all strains of treated bacteria and fungi. Staphylococcus aureus, Lysteria monocytogenes, and Salmonella typhimurium proved to be the most sensitive bacterial strains. Penicillium funiculosum proved to be the most sensitive micromycete, while P. ochrochloron and P. verrucosum var. cyclopium the most resistant micromycetes. The pygidial secretion of C. coriaceus has showed antibacterial potential solely against Pseudomonas aeruginosa and antifungal activity against Aspergillus fumigatus, A. versicolor, A. ochraceus, and P. ochrochloron. Antibacterial properties of pygidial gland secretion of A. parallelepipedus were achieved against P. aeruginosa, while antifungal activity was detected against five of the eight tested micromycetes (A. fumigatus, A. versicolor, A. ochraceus, Trichoderma viride, and P. verrucosum var. cyclopium). Commercial antibiotics Streptomycin and Ampicillin and mycotics Ketoconazole and Bifonazole, applied as the positive controls, showed higher antibacterial/antifungal properties for all bacterial and fungal strains. The results of this observation might have a significant impact on the environmental aspects and possible medical purpose in the future.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Naturwissenschaften",
title = "Antimicrobial activity of the pygidial gland secretion of three ground beetle species (Insecta: Coleoptera: Carabidae)",
volume = "103",
number = "3-4",
pages = "34",
doi = "10.1007/s00114-016-1358-z"
}

Nenadic, M., Soković, M., Glamočlija, J., Ćirić, A. D., Peric-Mataruga, V., Ilijin, L., Tešević, V., Vujisić, L. V., Todosijević, M., Vesović, N.,& Ćurčić, S.. (2016). Antimicrobial activity of the pygidial gland secretion of three ground beetle species (Insecta: Coleoptera: Carabidae). in Naturwissenschaften
Springer Heidelberg, Heidelberg., 103(3-4), 34.
https://doi.org/10.1007/s00114-016-1358-z

Nenadic M, Soković M, Glamočlija J, Ćirić AD, Peric-Mataruga V, Ilijin L, Tešević V, Vujisić LV, Todosijević M, Vesović N, Ćurčić S. Antimicrobial activity of the pygidial gland secretion of three ground beetle species (Insecta: Coleoptera: Carabidae). in Naturwissenschaften. 2016;103(3-4):34.
doi:10.1007/s00114-016-1358-z .

Nenadic, Marija, Soković, Marina, Glamočlija, Jasmina, Ćirić, Ana D., Peric-Mataruga, Vesna, Ilijin, Larisa, Tešević, Vele, Vujisić, Ljubodrag V., Todosijević, Marina, Vesović, Nikola, Ćurčić, Srećko, "Antimicrobial activity of the pygidial gland secretion of three ground beetle species (Insecta: Coleoptera: Carabidae)" in Naturwissenschaften, 103, no. 3-4 (2016):34,
https://doi.org/10.1007/s00114-016-1358-z . .

TY  - JOUR
AU  - Mileski, Ksenija S.
AU  - Ćirić, Ana D.
AU  - Trifunović, Snežana S.
AU  - Ristić, Mihailo S.
AU  - Soković, Marina
AU  - Matevski, Vlado S.
AU  - Tešević, Vele
AU  - Jadranin, Milka
AU  - Marin, Petar D.
AU  - Džamić, Ana M.
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3521
AB  - GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.
PB  - Royal Soc Chemistry, Cambridge
T2  - Food and Function
T1  - Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1
VL  - 7
IS  - 9
SP  - 4061
EP  - 4074
DO  - 10.1039/c6fo01018k
ER  - 

@article{
author = "Mileski, Ksenija S. and Ćirić, Ana D. and Trifunović, Snežana S. and Ristić, Mihailo S. and Soković, Marina and Matevski, Vlado S. and Tešević, Vele and Jadranin, Milka and Marin, Petar D. and Džamić, Ana M.",
year = "2016",
abstract = "GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Food and Function",
title = "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1",
volume = "7",
number = "9",
pages = "4061-4074",
doi = "10.1039/c6fo01018k"
}

Mileski, K. S., Ćirić, A. D., Trifunović, S. S., Ristić, M. S., Soković, M., Matevski, V. S., Tešević, V., Jadranin, M., Marin, P. D.,& Džamić, A. M.. (2016). Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food and Function
Royal Soc Chemistry, Cambridge., 7(9), 4061-4074.
https://doi.org/10.1039/c6fo01018k

Mileski KS, Ćirić AD, Trifunović SS, Ristić MS, Soković M, Matevski VS, Tešević V, Jadranin M, Marin PD, Džamić AM. Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food and Function. 2016;7(9):4061-4074.
doi:10.1039/c6fo01018k .

Mileski, Ksenija S., Ćirić, Ana D., Trifunović, Snežana S., Ristić, Mihailo S., Soković, Marina, Matevski, Vlado S., Tešević, Vele, Jadranin, Milka, Marin, Petar D., Džamić, Ana M., "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1" in Food and Function, 7, no. 9 (2016):4061-4074,
https://doi.org/10.1039/c6fo01018k . .

TY  - JOUR
AU  - Bukvicki, Danka
AU  - Ćirić, Ana D.
AU  - Soković, Marina
AU  - Vannini, Lucia
AU  - Nissen, Lorenzo
AU  - Novaković, Miroslav M.
AU  - Vujisić, Ljubodrag V.
AU  - Asakawa, Yoshinori
AU  - Marin, Petar D.
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2374
AB  - The chemical composition, antimicrobial and antiquorum sensing activity of the essential oil of Micromeria thymifolia (Scop.) Fritsch were investigated. Limonene, piperitone epoxide and piperitenone epoxide were found as the main constituents using a gas chromatography-mass spectrometry technique. In vitro antimicrobial activity of the oil was tested against six bacterial and seven fungal strains and high antimicrobial potential was noticed. Minimum inhibitory concentration varied from 0.031 mg/mL to 0.5 mg/mL for bacterial and 0.062 mg/mL to 0.5 mg/mL for fungal strains. The antiquorum properties of the essential oil were evaluated on Pseudomonas aeruginosa PAO1. The oil was tested at subMiC concentrations for anti-quorum sensing activity. The analyses on quorum-sensing functions have been carried out by evaluating twitching and swarming of bacterial cultures and the total amount of pyocyanin production produced by P. aeruginosa. This study showed that M thymifolia essential oil exhibited antiquorum sensing activity and may be used as an antipathogenic drug.
PB  - Natural Products Inc, Westerville
T2  - Natural Product Communications
T1  - Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa
VL  - 11
IS  - 12
SP  - 1903
EP  - 1906
UR  - https://hdl.handle.net/21.15107/rcub_cherry_2374
ER  - 

@article{
author = "Bukvicki, Danka and Ćirić, Ana D. and Soković, Marina and Vannini, Lucia and Nissen, Lorenzo and Novaković, Miroslav M. and Vujisić, Ljubodrag V. and Asakawa, Yoshinori and Marin, Petar D.",
year = "2016",
abstract = "The chemical composition, antimicrobial and antiquorum sensing activity of the essential oil of Micromeria thymifolia (Scop.) Fritsch were investigated. Limonene, piperitone epoxide and piperitenone epoxide were found as the main constituents using a gas chromatography-mass spectrometry technique. In vitro antimicrobial activity of the oil was tested against six bacterial and seven fungal strains and high antimicrobial potential was noticed. Minimum inhibitory concentration varied from 0.031 mg/mL to 0.5 mg/mL for bacterial and 0.062 mg/mL to 0.5 mg/mL for fungal strains. The antiquorum properties of the essential oil were evaluated on Pseudomonas aeruginosa PAO1. The oil was tested at subMiC concentrations for anti-quorum sensing activity. The analyses on quorum-sensing functions have been carried out by evaluating twitching and swarming of bacterial cultures and the total amount of pyocyanin production produced by P. aeruginosa. This study showed that M thymifolia essential oil exhibited antiquorum sensing activity and may be used as an antipathogenic drug.",
publisher = "Natural Products Inc, Westerville",
journal = "Natural Product Communications",
title = "Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa",
volume = "11",
number = "12",
pages = "1903-1906",
url = "https://hdl.handle.net/21.15107/rcub_cherry_2374"
}

Bukvicki, D., Ćirić, A. D., Soković, M., Vannini, L., Nissen, L., Novaković, M. M., Vujisić, L. V., Asakawa, Y.,& Marin, P. D.. (2016). Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa. in Natural Product Communications
Natural Products Inc, Westerville., 11(12), 1903-1906.
https://hdl.handle.net/21.15107/rcub_cherry_2374

Bukvicki D, Ćirić AD, Soković M, Vannini L, Nissen L, Novaković MM, Vujisić LV, Asakawa Y, Marin PD. Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa. in Natural Product Communications. 2016;11(12):1903-1906.
https://hdl.handle.net/21.15107/rcub_cherry_2374 .

Bukvicki, Danka, Ćirić, Ana D., Soković, Marina, Vannini, Lucia, Nissen, Lorenzo, Novaković, Miroslav M., Vujisić, Ljubodrag V., Asakawa, Yoshinori, Marin, Petar D., "Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa" in Natural Product Communications, 11, no. 12 (2016):1903-1906,
https://hdl.handle.net/21.15107/rcub_cherry_2374 .

TY  - JOUR
AU  - Pejin, Boris
AU  - Glamočlija, Jasmina
AU  - Ćirić, Ana D.
AU  - Radotić, Ksenija
AU  - Vajs, Vlatka
AU  - Tešević, Vele
AU  - Hegedis, Aleksandar
AU  - Karaman, Ivo
AU  - Horvatovic, Mladen
AU  - Soković, Marina
PY  - 2012
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1565
AB  - The antimicrobial activity of the freshwater bryozoan Hyalinella punctata (Hancock, 1850) was tested by microdilution method against eight bacteria and eight fungi for the first time. All five crude extracts (hexane, acetone, dimethyl sulfoxide, methanol and water) showed good antibacterial and antifungal potential in vitro wherein the acetone extract was the most active (MICs 0.50-7.00 mu g/ml and MBCs 2.50-10.00 mu g/ml).
PB  - Inst Materials Physics, Bucharest
T2  - Digest Journal of Nanomaterials and Biostructures
T1  - Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850)
VL  - 7
IS  - 3
SP  - 1021
EP  - 1026
UR  - https://hdl.handle.net/21.15107/rcub_cherry_1565
ER  - 

@article{
author = "Pejin, Boris and Glamočlija, Jasmina and Ćirić, Ana D. and Radotić, Ksenija and Vajs, Vlatka and Tešević, Vele and Hegedis, Aleksandar and Karaman, Ivo and Horvatovic, Mladen and Soković, Marina",
year = "2012",
abstract = "The antimicrobial activity of the freshwater bryozoan Hyalinella punctata (Hancock, 1850) was tested by microdilution method against eight bacteria and eight fungi for the first time. All five crude extracts (hexane, acetone, dimethyl sulfoxide, methanol and water) showed good antibacterial and antifungal potential in vitro wherein the acetone extract was the most active (MICs 0.50-7.00 mu g/ml and MBCs 2.50-10.00 mu g/ml).",
publisher = "Inst Materials Physics, Bucharest",
journal = "Digest Journal of Nanomaterials and Biostructures",
title = "Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850)",
volume = "7",
number = "3",
pages = "1021-1026",
url = "https://hdl.handle.net/21.15107/rcub_cherry_1565"
}

Pejin, B., Glamočlija, J., Ćirić, A. D., Radotić, K., Vajs, V., Tešević, V., Hegedis, A., Karaman, I., Horvatovic, M.,& Soković, M.. (2012). Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850). in Digest Journal of Nanomaterials and Biostructures
Inst Materials Physics, Bucharest., 7(3), 1021-1026.
https://hdl.handle.net/21.15107/rcub_cherry_1565

Pejin B, Glamočlija J, Ćirić AD, Radotić K, Vajs V, Tešević V, Hegedis A, Karaman I, Horvatovic M, Soković M. Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850). in Digest Journal of Nanomaterials and Biostructures. 2012;7(3):1021-1026.
https://hdl.handle.net/21.15107/rcub_cherry_1565 .

Pejin, Boris, Glamočlija, Jasmina, Ćirić, Ana D., Radotić, Ksenija, Vajs, Vlatka, Tešević, Vele, Hegedis, Aleksandar, Karaman, Ivo, Horvatovic, Mladen, Soković, Marina, "Antimicrobial Activity of the Freshwater Bryozoan Hyalinella Punctata (Hancock, 1850)" in Digest Journal of Nanomaterials and Biostructures, 7, no. 3 (2012):1021-1026,
https://hdl.handle.net/21.15107/rcub_cherry_1565 .