TY  - DATA
AU  - Marković, Violeta
AU  - Erić, Slavica
AU  - Stanojković, Tatjana
AU  - Gligorijević, Nevenka
AU  - Aranđelović, Sandra
AU  - Todorović, Nina
AU  - Trifunović, Snežana S.
AU  - Manojlović, Nedeljko
AU  - Jelić, Ratomir
AU  - Joksović, Milan D.
PY  - 2011
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3573
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Bioorganic and Medicinal Chemistry Letters
T1  - Supplementary data for article: Marković, V.; Erić, S.; Stanojković, T.; Gligorijević, N.; Aranđelović, S.; Todorović, N.; Trifunović, S. S.; Manojlović, N.; Jelic, R.; Joksović, M. D. Antiproliferative Activity and QSAR Studies of a Series of New 4-Aminomethylidene Derivatives of Some Pyrazol-5-Ones. Bioorganic and Medicinal Chemistry Letters 2011, 21 (15), 4416–4421. https://doi.org/10.1016/j.bmcl.2011.06.025
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3573
ER  - 

@misc{
author = "Marković, Violeta and Erić, Slavica and Stanojković, Tatjana and Gligorijević, Nevenka and Aranđelović, Sandra and Todorović, Nina and Trifunović, Snežana S. and Manojlović, Nedeljko and Jelić, Ratomir and Joksović, Milan D.",
year = "2011",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Bioorganic and Medicinal Chemistry Letters",
title = "Supplementary data for article: Marković, V.; Erić, S.; Stanojković, T.; Gligorijević, N.; Aranđelović, S.; Todorović, N.; Trifunović, S. S.; Manojlović, N.; Jelic, R.; Joksović, M. D. Antiproliferative Activity and QSAR Studies of a Series of New 4-Aminomethylidene Derivatives of Some Pyrazol-5-Ones. Bioorganic and Medicinal Chemistry Letters 2011, 21 (15), 4416–4421. https://doi.org/10.1016/j.bmcl.2011.06.025",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3573"
}

Marković, V., Erić, S., Stanojković, T., Gligorijević, N., Aranđelović, S., Todorović, N., Trifunović, S. S., Manojlović, N., Jelić, R.,& Joksović, M. D.. (2011). Supplementary data for article: Marković, V.; Erić, S.; Stanojković, T.; Gligorijević, N.; Aranđelović, S.; Todorović, N.; Trifunović, S. S.; Manojlović, N.; Jelic, R.; Joksović, M. D. Antiproliferative Activity and QSAR Studies of a Series of New 4-Aminomethylidene Derivatives of Some Pyrazol-5-Ones. Bioorganic and Medicinal Chemistry Letters 2011, 21 (15), 4416–4421. https://doi.org/10.1016/j.bmcl.2011.06.025. in Bioorganic and Medicinal Chemistry Letters
Pergamon-Elsevier Science Ltd, Oxford..
https://hdl.handle.net/21.15107/rcub_cherry_3573

Marković V, Erić S, Stanojković T, Gligorijević N, Aranđelović S, Todorović N, Trifunović SS, Manojlović N, Jelić R, Joksović MD. Supplementary data for article: Marković, V.; Erić, S.; Stanojković, T.; Gligorijević, N.; Aranđelović, S.; Todorović, N.; Trifunović, S. S.; Manojlović, N.; Jelic, R.; Joksović, M. D. Antiproliferative Activity and QSAR Studies of a Series of New 4-Aminomethylidene Derivatives of Some Pyrazol-5-Ones. Bioorganic and Medicinal Chemistry Letters 2011, 21 (15), 4416–4421. https://doi.org/10.1016/j.bmcl.2011.06.025. in Bioorganic and Medicinal Chemistry Letters. 2011;.
https://hdl.handle.net/21.15107/rcub_cherry_3573 .

Marković, Violeta, Erić, Slavica, Stanojković, Tatjana, Gligorijević, Nevenka, Aranđelović, Sandra, Todorović, Nina, Trifunović, Snežana S., Manojlović, Nedeljko, Jelić, Ratomir, Joksović, Milan D., "Supplementary data for article: Marković, V.; Erić, S.; Stanojković, T.; Gligorijević, N.; Aranđelović, S.; Todorović, N.; Trifunović, S. S.; Manojlović, N.; Jelic, R.; Joksović, M. D. Antiproliferative Activity and QSAR Studies of a Series of New 4-Aminomethylidene Derivatives of Some Pyrazol-5-Ones. Bioorganic and Medicinal Chemistry Letters 2011, 21 (15), 4416–4421. https://doi.org/10.1016/j.bmcl.2011.06.025" in Bioorganic and Medicinal Chemistry Letters (2011),
https://hdl.handle.net/21.15107/rcub_cherry_3573 .

TY  - JOUR
AU  - Marković, Violeta
AU  - Erić, Slavica
AU  - Stanojković, Tatjana
AU  - Gligorijević, Nevenka
AU  - Aranđelović, Sandra
AU  - Todorović, Nina
AU  - Trifunović, Snežana S.
AU  - Manojlović, Nedeljko
AU  - Jelić, Ratomir
AU  - Joksović, Milan D.
PY  - 2011
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1175
AB  - Twenty five 4-aminomethylidene derivatives obtained from 3-phenyl-2-pyrazolin-5-one and 1,3-diphenyl-2-pyrazolin-5-one were synthesized and tested for their antiproliferative activity against human breast cancer MDA-MB-361 and MDA-MB-453 cell lines. The compounds derived from 1,3-diphenyl-2-pyrazolin-5-one exhibited the most remarkable activity in the treatment of both cell lines. In vitro antiproliferative activities were accompanied by an important apoptotic fraction of both cell lines; also, compounds inhibited key endothelial cell functions implicated in invasion and angiogenesis. QSAR methods were performed in order to analyze the influence of structural features of the compounds investigated on the antiproliferative potential on MDA-MB-361 and MDA-MB-453 cancer cells. One-parameter heuristic analysis was performed and different whole molecule and fragmental descriptors were considered for rationalization of mechanism of interaction of these compounds with active place of hypothetical target included in tumorigenesis.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Bioorganic and Medicinal Chemistry Letters
T1  - Antiproliferative activity and QSAR studies of a series of new 4-aminomethylidene derivatives of some pyrazol-5-ones
VL  - 21
IS  - 15
SP  - 4416
EP  - 4421
DO  - 10.1016/j.bmcl.2011.06.025
ER  - 

@article{
author = "Marković, Violeta and Erić, Slavica and Stanojković, Tatjana and Gligorijević, Nevenka and Aranđelović, Sandra and Todorović, Nina and Trifunović, Snežana S. and Manojlović, Nedeljko and Jelić, Ratomir and Joksović, Milan D.",
year = "2011",
abstract = "Twenty five 4-aminomethylidene derivatives obtained from 3-phenyl-2-pyrazolin-5-one and 1,3-diphenyl-2-pyrazolin-5-one were synthesized and tested for their antiproliferative activity against human breast cancer MDA-MB-361 and MDA-MB-453 cell lines. The compounds derived from 1,3-diphenyl-2-pyrazolin-5-one exhibited the most remarkable activity in the treatment of both cell lines. In vitro antiproliferative activities were accompanied by an important apoptotic fraction of both cell lines; also, compounds inhibited key endothelial cell functions implicated in invasion and angiogenesis. QSAR methods were performed in order to analyze the influence of structural features of the compounds investigated on the antiproliferative potential on MDA-MB-361 and MDA-MB-453 cancer cells. One-parameter heuristic analysis was performed and different whole molecule and fragmental descriptors were considered for rationalization of mechanism of interaction of these compounds with active place of hypothetical target included in tumorigenesis.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Bioorganic and Medicinal Chemistry Letters",
title = "Antiproliferative activity and QSAR studies of a series of new 4-aminomethylidene derivatives of some pyrazol-5-ones",
volume = "21",
number = "15",
pages = "4416-4421",
doi = "10.1016/j.bmcl.2011.06.025"
}

Marković, V., Erić, S., Stanojković, T., Gligorijević, N., Aranđelović, S., Todorović, N., Trifunović, S. S., Manojlović, N., Jelić, R.,& Joksović, M. D.. (2011). Antiproliferative activity and QSAR studies of a series of new 4-aminomethylidene derivatives of some pyrazol-5-ones. in Bioorganic and Medicinal Chemistry Letters
Pergamon-Elsevier Science Ltd, Oxford., 21(15), 4416-4421.
https://doi.org/10.1016/j.bmcl.2011.06.025

Marković V, Erić S, Stanojković T, Gligorijević N, Aranđelović S, Todorović N, Trifunović SS, Manojlović N, Jelić R, Joksović MD. Antiproliferative activity and QSAR studies of a series of new 4-aminomethylidene derivatives of some pyrazol-5-ones. in Bioorganic and Medicinal Chemistry Letters. 2011;21(15):4416-4421.
doi:10.1016/j.bmcl.2011.06.025 .

Marković, Violeta, Erić, Slavica, Stanojković, Tatjana, Gligorijević, Nevenka, Aranđelović, Sandra, Todorović, Nina, Trifunović, Snežana S., Manojlović, Nedeljko, Jelić, Ratomir, Joksović, Milan D., "Antiproliferative activity and QSAR studies of a series of new 4-aminomethylidene derivatives of some pyrazol-5-ones" in Bioorganic and Medicinal Chemistry Letters, 21, no. 15 (2011):4416-4421,
https://doi.org/10.1016/j.bmcl.2011.06.025 . .