TY  - JOUR
AU  - Perušković, Danica S.
AU  - Stevanović, Nikola R.
AU  - Kovačević, Gordana
AU  - Stanković, Dalibor
AU  - Lolić, Aleksandar
AU  - Baošić, Rada
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3976
AB  - A new glucose biosensor for selective and sensitive determination of glucose in beverage samples was developed. A copper complex with a Schiff base, N,N’-bis(acetylacetonato) propylenediimine, was used as a mediator. It was mixed with glucose oxidase (GOx) and prepared as carbon paste electrode (CPE). Cyclic voltammetry was used for electrochemical measurements. The biosensor showed improved sensitivity when enzyme mediator ratio was 1 : 5, and working pH was 6.6 in 0.1 M phosphate buffer. The linear response of the biosensor for glucose concentration was in the range from 0.5 to 10 mM, with low detection limit of 0.36 mM (calculated as 3 s/n) and sensitivity of 0.16 μA/mM. The reproducibility of the biosensor, calculated as relative standard deviation, was 1.9% for 6 intra-day measurements. Biosensor was stored at +4 °C between experiments, and it was stable during 14 days after the preparation. The developed biosensor was applied on determination of glucose in commercial beverages (apple and cherry juice) and obtained results showed good agreement with the reference method.
PB  - Wiley-Blackwell
T2  - ChemistrySelect
T1  - Application of N,N’-Bis(acetylacetonato)propylenediimine Copper(II) Complex as Mediator for Glucose Biosensor
VL  - 5
IS  - 5
SP  - 1671
EP  - 1675
DO  - 10.1002/slct.201904873
ER  - 

@article{
author = "Perušković, Danica S. and Stevanović, Nikola R. and Kovačević, Gordana and Stanković, Dalibor and Lolić, Aleksandar and Baošić, Rada",
year = "2020",
abstract = "A new glucose biosensor for selective and sensitive determination of glucose in beverage samples was developed. A copper complex with a Schiff base, N,N’-bis(acetylacetonato) propylenediimine, was used as a mediator. It was mixed with glucose oxidase (GOx) and prepared as carbon paste electrode (CPE). Cyclic voltammetry was used for electrochemical measurements. The biosensor showed improved sensitivity when enzyme mediator ratio was 1 : 5, and working pH was 6.6 in 0.1 M phosphate buffer. The linear response of the biosensor for glucose concentration was in the range from 0.5 to 10 mM, with low detection limit of 0.36 mM (calculated as 3 s/n) and sensitivity of 0.16 μA/mM. The reproducibility of the biosensor, calculated as relative standard deviation, was 1.9% for 6 intra-day measurements. Biosensor was stored at +4 °C between experiments, and it was stable during 14 days after the preparation. The developed biosensor was applied on determination of glucose in commercial beverages (apple and cherry juice) and obtained results showed good agreement with the reference method.",
publisher = "Wiley-Blackwell",
journal = "ChemistrySelect",
title = "Application of N,N’-Bis(acetylacetonato)propylenediimine Copper(II) Complex as Mediator for Glucose Biosensor",
volume = "5",
number = "5",
pages = "1671-1675",
doi = "10.1002/slct.201904873"
}

Perušković, D. S., Stevanović, N. R., Kovačević, G., Stanković, D., Lolić, A.,& Baošić, R.. (2020). Application of N,N’-Bis(acetylacetonato)propylenediimine Copper(II) Complex as Mediator for Glucose Biosensor. in ChemistrySelect
Wiley-Blackwell., 5(5), 1671-1675.
https://doi.org/10.1002/slct.201904873

Perušković DS, Stevanović NR, Kovačević G, Stanković D, Lolić A, Baošić R. Application of N,N’-Bis(acetylacetonato)propylenediimine Copper(II) Complex as Mediator for Glucose Biosensor. in ChemistrySelect. 2020;5(5):1671-1675.
doi:10.1002/slct.201904873 .

Perušković, Danica S., Stevanović, Nikola R., Kovačević, Gordana, Stanković, Dalibor, Lolić, Aleksandar, Baošić, Rada, "Application of N,N’-Bis(acetylacetonato)propylenediimine Copper(II) Complex as Mediator for Glucose Biosensor" in ChemistrySelect, 5, no. 5 (2020):1671-1675,
https://doi.org/10.1002/slct.201904873 . .

TY  - JOUR
AU  - Antunović, Vesna R.
AU  - Tešanović, Slavna
AU  - Perušković, Danica S.
AU  - Stevanović, Nikola R.
AU  - Baošić, Rada
AU  - Mandić, Snežana D.
AU  - Lolić, Aleksandar
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2122
AB  - The is work presents the development of a flow injection system for differential pulse amperometry (DPA) for diazepam determination in the presence of oxygen. The thin flow cell consisted of the bare glassy carbon electrode, reference silver/silver chloride, and stainless steel as the auxiliary electrode. Electrochemical reduction of diazepam (DZP) was characterised by cyclic voltammetry. Azomethine reduction peak was used for DZP quantification. The detector response was linear in the range 20-250 mu mol/dm(3) of diazepam, with a calculated detection limit of 3.83 mu g/cm(3). Intraday and interday precision were 1.53 and 10.8%, respectively. The method was applied on three beverage samples, energetic drink, and two different beer samples, and obtained recoveries were from 93.65 up to 104.96%. The throughoutput of the method was up to 90 analyses per hour.
PB  - Hindawi Ltd, London
T2  - Journal of Analytical Methods in Chemistry
T1  - Development of a Flow Injection System for Differential Pulse Amperometry and Its Application for Diazepam Determination
DO  - 10.1155/2018/6121489
ER  - 

@article{
author = "Antunović, Vesna R. and Tešanović, Slavna and Perušković, Danica S. and Stevanović, Nikola R. and Baošić, Rada and Mandić, Snežana D. and Lolić, Aleksandar",
year = "2018",
abstract = "The is work presents the development of a flow injection system for differential pulse amperometry (DPA) for diazepam determination in the presence of oxygen. The thin flow cell consisted of the bare glassy carbon electrode, reference silver/silver chloride, and stainless steel as the auxiliary electrode. Electrochemical reduction of diazepam (DZP) was characterised by cyclic voltammetry. Azomethine reduction peak was used for DZP quantification. The detector response was linear in the range 20-250 mu mol/dm(3) of diazepam, with a calculated detection limit of 3.83 mu g/cm(3). Intraday and interday precision were 1.53 and 10.8%, respectively. The method was applied on three beverage samples, energetic drink, and two different beer samples, and obtained recoveries were from 93.65 up to 104.96%. The throughoutput of the method was up to 90 analyses per hour.",
publisher = "Hindawi Ltd, London",
journal = "Journal of Analytical Methods in Chemistry",
title = "Development of a Flow Injection System for Differential Pulse Amperometry and Its Application for Diazepam Determination",
doi = "10.1155/2018/6121489"
}

Antunović, V. R., Tešanović, S., Perušković, D. S., Stevanović, N. R., Baošić, R., Mandić, S. D.,& Lolić, A.. (2018). Development of a Flow Injection System for Differential Pulse Amperometry and Its Application for Diazepam Determination. in Journal of Analytical Methods in Chemistry
Hindawi Ltd, London..
https://doi.org/10.1155/2018/6121489

Antunović VR, Tešanović S, Perušković DS, Stevanović NR, Baošić R, Mandić SD, Lolić A. Development of a Flow Injection System for Differential Pulse Amperometry and Its Application for Diazepam Determination. in Journal of Analytical Methods in Chemistry. 2018;.
doi:10.1155/2018/6121489 .

Antunović, Vesna R., Tešanović, Slavna, Perušković, Danica S., Stevanović, Nikola R., Baošić, Rada, Mandić, Snežana D., Lolić, Aleksandar, "Development of a Flow Injection System for Differential Pulse Amperometry and Its Application for Diazepam Determination" in Journal of Analytical Methods in Chemistry (2018),
https://doi.org/10.1155/2018/6121489 . .

TY  - JOUR
AU  - Stevanović, Nikola R.
AU  - Perušković, Danica S.
AU  - Gašić, Uroš M.
AU  - Antunović, Vesna R.
AU  - Lolić, Aleksandar
AU  - Baošić, Rada
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2443
AB  - The objectives of this study were to gain insights into structure-retention relationships and to propose the model to estimating their retention. Chromatographic investigation of series of 36 Schiff bases and their copper(II) and nickel(II) complexes was performed under both normaland reverse-phase conditions. Chemical structures of the compounds were characterized by molecular descriptors which are calculated from the structure and related to the chromatographic retention parameters by multiple linear regression analysis. Effects of chelation on retention parameters of investigated compounds, under normal-and reverse-phase chromatographic conditions, were analyzed by principal component analysis, quantitative structure-retention relationship and quantitative structure-activity relationship models were developed on the basis of theoretical molecular descriptors, calculated exclusively from molecular structure, and parameters of retention and lipophilicity.
PB  - Wiley, Hoboken
T2  - Biomedical Chromatography
T1  - Effect of substituents on prediction of TLC retention of tetradentate Schiff bases and their Copper(II) and Nickel(II) complexes
VL  - 31
IS  - 3
DO  - 10.1002/bmc.3810
ER  - 

@article{
author = "Stevanović, Nikola R. and Perušković, Danica S. and Gašić, Uroš M. and Antunović, Vesna R. and Lolić, Aleksandar and Baošić, Rada",
year = "2017",
abstract = "The objectives of this study were to gain insights into structure-retention relationships and to propose the model to estimating their retention. Chromatographic investigation of series of 36 Schiff bases and their copper(II) and nickel(II) complexes was performed under both normaland reverse-phase conditions. Chemical structures of the compounds were characterized by molecular descriptors which are calculated from the structure and related to the chromatographic retention parameters by multiple linear regression analysis. Effects of chelation on retention parameters of investigated compounds, under normal-and reverse-phase chromatographic conditions, were analyzed by principal component analysis, quantitative structure-retention relationship and quantitative structure-activity relationship models were developed on the basis of theoretical molecular descriptors, calculated exclusively from molecular structure, and parameters of retention and lipophilicity.",
publisher = "Wiley, Hoboken",
journal = "Biomedical Chromatography",
title = "Effect of substituents on prediction of TLC retention of tetradentate Schiff bases and their Copper(II) and Nickel(II) complexes",
volume = "31",
number = "3",
doi = "10.1002/bmc.3810"
}

Stevanović, N. R., Perušković, D. S., Gašić, U. M., Antunović, V. R., Lolić, A.,& Baošić, R.. (2017). Effect of substituents on prediction of TLC retention of tetradentate Schiff bases and their Copper(II) and Nickel(II) complexes. in Biomedical Chromatography
Wiley, Hoboken., 31(3).
https://doi.org/10.1002/bmc.3810

Stevanović NR, Perušković DS, Gašić UM, Antunović VR, Lolić A, Baošić R. Effect of substituents on prediction of TLC retention of tetradentate Schiff bases and their Copper(II) and Nickel(II) complexes. in Biomedical Chromatography. 2017;31(3).
doi:10.1002/bmc.3810 .

Stevanović, Nikola R., Perušković, Danica S., Gašić, Uroš M., Antunović, Vesna R., Lolić, Aleksandar, Baošić, Rada, "Effect of substituents on prediction of TLC retention of tetradentate Schiff bases and their Copper(II) and Nickel(II) complexes" in Biomedical Chromatography, 31, no. 3 (2017),
https://doi.org/10.1002/bmc.3810 . .

TY  - JOUR
AU  - Đogo Mračević, Svetlana
AU  - Arnautović, Slađana
AU  - Lolić, Aleksandar
AU  - Perušković, Danica S.
AU  - Bakić, Tamara
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4988
AB  - Porast životnog standarda je znatno uticao na ishranu i proizvodnju
hrane. Meso i mesne prerađevine su, zbog svoje visoke nutritivne vrednosti,
značajan segment ljudske ishrane i bogat izvor elemenata u tragovima
poput Fe, Zn, Mn, Ca, K, Mg, ali s druge strane, mogu akumulirati
teške metale kao što su Cd i Pb. Toksične koncentracije metala u
mišićima su retke, ali ih jetra i bubrezi akumuliraju. U industriji mesa,
kao aditivi, važnu ulogu imaju nitriti, koji vremenom mogu preći u toksične
i kancerogene nitrozamine što zavisi od pH, temperature, redoks
potencijala kao i količine dodatih nitrita. U praćenju kvaliteta mesa
i mesnih prerađevina, bitno je pratiti sadržaj metala, ali i rezidualne
koncentracije nitrita.
Cilj ovog rada je bio određivanje sadržaja Cd, Cu, Fe i Zn u uzorcima
svinjskog i goveđeg mesa i svinjskoj džigerici, te sadržaja nitrita u
uzorcima svinjskog i goveđeg mesa i mesnim prerađevinama – paštetama
i kobasicama. Metali su određivani primenom metode ICP- AES,
a nitriti standardnom metodom SRPS ISO 2918/1999. Sadržaj gvožđa
u džigerici je 189,2 μg/kg, svinjskom i goveđem mesu 89,78 μg/kg, odnosno
87,79 μg/kg. Sadržaj Cu i Zn u svim ispitivanim uzorcima je u
dozvoljenim granicama, a Cd se u uzorku svinjskog mesa nalazi 1,2
puta više nego što je dozvoljeno. Na osnovu dobijenih rezultata može
se pretpostaviti da je inicijalno dodata količina nitrita u proizvodnom
procesu bila u skladu sa zakonski definisanim ograničenjem.
PB  - Časopis društva za ishranu Srbije
T2  - Hrana i ishrana
T1  - Determination of nitrite and heavy metals content in meat and its product
T1  - Određivanje sadržaja nitrita i teških metala u mesu i proizvodima od mesa
VL  - 52
IS  - 2
SP  - 24
EP  - 29
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4988
ER  - 

@article{
author = "Đogo Mračević, Svetlana and Arnautović, Slađana and Lolić, Aleksandar and Perušković, Danica S. and Bakić, Tamara",
year = "2017",
abstract = "Porast životnog standarda je znatno uticao na ishranu i proizvodnju
hrane. Meso i mesne prerađevine su, zbog svoje visoke nutritivne vrednosti,
značajan segment ljudske ishrane i bogat izvor elemenata u tragovima
poput Fe, Zn, Mn, Ca, K, Mg, ali s druge strane, mogu akumulirati
teške metale kao što su Cd i Pb. Toksične koncentracije metala u
mišićima su retke, ali ih jetra i bubrezi akumuliraju. U industriji mesa,
kao aditivi, važnu ulogu imaju nitriti, koji vremenom mogu preći u toksične
i kancerogene nitrozamine što zavisi od pH, temperature, redoks
potencijala kao i količine dodatih nitrita. U praćenju kvaliteta mesa
i mesnih prerađevina, bitno je pratiti sadržaj metala, ali i rezidualne
koncentracije nitrita.
Cilj ovog rada je bio određivanje sadržaja Cd, Cu, Fe i Zn u uzorcima
svinjskog i goveđeg mesa i svinjskoj džigerici, te sadržaja nitrita u
uzorcima svinjskog i goveđeg mesa i mesnim prerađevinama – paštetama
i kobasicama. Metali su određivani primenom metode ICP- AES,
a nitriti standardnom metodom SRPS ISO 2918/1999. Sadržaj gvožđa
u džigerici je 189,2 μg/kg, svinjskom i goveđem mesu 89,78 μg/kg, odnosno
87,79 μg/kg. Sadržaj Cu i Zn u svim ispitivanim uzorcima je u
dozvoljenim granicama, a Cd se u uzorku svinjskog mesa nalazi 1,2
puta više nego što je dozvoljeno. Na osnovu dobijenih rezultata može
se pretpostaviti da je inicijalno dodata količina nitrita u proizvodnom
procesu bila u skladu sa zakonski definisanim ograničenjem.",
publisher = "Časopis društva za ishranu Srbije",
journal = "Hrana i ishrana",
title = "Determination of nitrite and heavy metals content in meat and its product, Određivanje sadržaja nitrita i teških metala u mesu i proizvodima od mesa",
volume = "52",
number = "2",
pages = "24-29",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4988"
}

Đogo Mračević, S., Arnautović, S., Lolić, A., Perušković, D. S.,& Bakić, T.. (2017). Determination of nitrite and heavy metals content in meat and its product. in Hrana i ishrana
Časopis društva za ishranu Srbije., 52(2), 24-29.
https://hdl.handle.net/21.15107/rcub_cherry_4988

Đogo Mračević S, Arnautović S, Lolić A, Perušković DS, Bakić T. Determination of nitrite and heavy metals content in meat and its product. in Hrana i ishrana. 2017;52(2):24-29.
https://hdl.handle.net/21.15107/rcub_cherry_4988 .

Đogo Mračević, Svetlana, Arnautović, Slađana, Lolić, Aleksandar, Perušković, Danica S., Bakić, Tamara, "Determination of nitrite and heavy metals content in meat and its product" in Hrana i ishrana, 52, no. 2 (2017):24-29,
https://hdl.handle.net/21.15107/rcub_cherry_4988 .

TY  - JOUR
AU  - Perušković, Danica S.
AU  - Gašić, Uroš M.
AU  - Antunović, Vesna R.
AU  - Lolić, Aleksandar
AU  - Baošić, Rada
AU  - Stevanović, Nikola R.
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2982
AB  - The objectives of this study were to gain insights into structure-retention relationships and to propose the model to estimating their retention. Chromatographic investigation of series of 36 Schiff bases and their copper(II) and nickel(II) complexes was performed under both normaland reverse-phase conditions. Chemical structures of the compounds were characterized by molecular descriptors which are calculated from the structure and related to the chromatographic retention parameters by multiple linear regression analysis. Effects of chelation on retention parameters of investigated compounds, under normal-and reverse-phase chromatographic conditions, were analyzed by principal component analysis, quantitative structure-retention relationship and quantitative structure-activity relationship models were developed on the basis of theoretical molecular descriptors, calculated exclusively from molecular structure, and parameters of retention and lipophilicity.
PB  - Wiley, Hoboken
T2  - Biomedical Chromatography
T1  - Effect of substituents on prediction of TLC retention of tetradentate Schiff bases and their Copper(II) and Nickel(II) complexes
VL  - 31
IS  - 3
DO  - 10.1002/bmc.3810
ER  - 

@article{
author = "Perušković, Danica S. and Gašić, Uroš M. and Antunović, Vesna R. and Lolić, Aleksandar and Baošić, Rada and Stevanović, Nikola R.",
year = "2017",
abstract = "The objectives of this study were to gain insights into structure-retention relationships and to propose the model to estimating their retention. Chromatographic investigation of series of 36 Schiff bases and their copper(II) and nickel(II) complexes was performed under both normaland reverse-phase conditions. Chemical structures of the compounds were characterized by molecular descriptors which are calculated from the structure and related to the chromatographic retention parameters by multiple linear regression analysis. Effects of chelation on retention parameters of investigated compounds, under normal-and reverse-phase chromatographic conditions, were analyzed by principal component analysis, quantitative structure-retention relationship and quantitative structure-activity relationship models were developed on the basis of theoretical molecular descriptors, calculated exclusively from molecular structure, and parameters of retention and lipophilicity.",
publisher = "Wiley, Hoboken",
journal = "Biomedical Chromatography",
title = "Effect of substituents on prediction of TLC retention of tetradentate Schiff bases and their Copper(II) and Nickel(II) complexes",
volume = "31",
number = "3",
doi = "10.1002/bmc.3810"
}

Perušković, D. S., Gašić, U. M., Antunović, V. R., Lolić, A., Baošić, R.,& Stevanović, N. R.. (2017). Effect of substituents on prediction of TLC retention of tetradentate Schiff bases and their Copper(II) and Nickel(II) complexes. in Biomedical Chromatography
Wiley, Hoboken., 31(3).
https://doi.org/10.1002/bmc.3810

Perušković DS, Gašić UM, Antunović VR, Lolić A, Baošić R, Stevanović NR. Effect of substituents on prediction of TLC retention of tetradentate Schiff bases and their Copper(II) and Nickel(II) complexes. in Biomedical Chromatography. 2017;31(3).
doi:10.1002/bmc.3810 .

Perušković, Danica S., Gašić, Uroš M., Antunović, Vesna R., Lolić, Aleksandar, Baošić, Rada, Stevanović, Nikola R., "Effect of substituents on prediction of TLC retention of tetradentate Schiff bases and their Copper(II) and Nickel(II) complexes" in Biomedical Chromatography, 31, no. 3 (2017),
https://doi.org/10.1002/bmc.3810 . .

TY  - CONF
AU  - Lolić, Aleksandar
AU  - Antunović, Vesna R.
AU  - Tešanović, Slavna
AU  - Perušković, Danica S.
AU  - Stevanović, Nikola R.
AU  - Baošić, Rada
AU  - Nikolić, Snežana
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4994
AB  - Diazepam belongs to the group of benzodiazepine drugs, and its consumption with alcohol enhances its sedative effect and absorption rate. That is why it is often used as “date rape drug” [1]. In our experiments we applied the flow injection system on diazepam determination on a bare glassy carbon electrode. The electrochemical determination of diazepam is based on reduction of the azomethine group yielding a dyhidrodiazepam. The single cathodic peak is caused by the reduction of diazepam by a two electron change. The reduction potential is highly dependent on pH value of the electrolyte, shifting to more negative potentials with higher pH [2].
PB  - ISEP Instituto Superior de Engenharia do Porto
C3  - 1st workshop on Electrochemistry Devices (Bio)Sensors, October 13-14, 2016, Porto, Portugal, Book of Abstracts pp 31
T1  - Determination of diazepam by flow-injection with amperometric detection in beverages
SP  - 37
EP  - 37
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4994
ER  - 

@conference{
author = "Lolić, Aleksandar and Antunović, Vesna R. and Tešanović, Slavna and Perušković, Danica S. and Stevanović, Nikola R. and Baošić, Rada and Nikolić, Snežana",
year = "2016",
abstract = "Diazepam belongs to the group of benzodiazepine drugs, and its consumption with alcohol enhances its sedative effect and absorption rate. That is why it is often used as “date rape drug” [1]. In our experiments we applied the flow injection system on diazepam determination on a bare glassy carbon electrode. The electrochemical determination of diazepam is based on reduction of the azomethine group yielding a dyhidrodiazepam. The single cathodic peak is caused by the reduction of diazepam by a two electron change. The reduction potential is highly dependent on pH value of the electrolyte, shifting to more negative potentials with higher pH [2].",
publisher = "ISEP Instituto Superior de Engenharia do Porto",
journal = "1st workshop on Electrochemistry Devices (Bio)Sensors, October 13-14, 2016, Porto, Portugal, Book of Abstracts pp 31",
title = "Determination of diazepam by flow-injection with amperometric detection in beverages",
pages = "37-37",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4994"
}

Lolić, A., Antunović, V. R., Tešanović, S., Perušković, D. S., Stevanović, N. R., Baošić, R.,& Nikolić, S.. (2016). Determination of diazepam by flow-injection with amperometric detection in beverages. in 1st workshop on Electrochemistry Devices (Bio)Sensors, October 13-14, 2016, Porto, Portugal, Book of Abstracts pp 31
ISEP Instituto Superior de Engenharia do Porto., 37-37.
https://hdl.handle.net/21.15107/rcub_cherry_4994

Lolić A, Antunović VR, Tešanović S, Perušković DS, Stevanović NR, Baošić R, Nikolić S. Determination of diazepam by flow-injection with amperometric detection in beverages. in 1st workshop on Electrochemistry Devices (Bio)Sensors, October 13-14, 2016, Porto, Portugal, Book of Abstracts pp 31. 2016;:37-37.
https://hdl.handle.net/21.15107/rcub_cherry_4994 .

Lolić, Aleksandar, Antunović, Vesna R., Tešanović, Slavna, Perušković, Danica S., Stevanović, Nikola R., Baošić, Rada, Nikolić, Snežana, "Determination of diazepam by flow-injection with amperometric detection in beverages" in 1st workshop on Electrochemistry Devices (Bio)Sensors, October 13-14, 2016, Porto, Portugal, Book of Abstracts pp 31 (2016):37-37,
https://hdl.handle.net/21.15107/rcub_cherry_4994 .

TY  - JOUR
AU  - Perušković, Danica S.
AU  - Daric, Branka
AU  - Blagus, Anita
AU  - Stevanović, Nikola R.
AU  - Pavlović, Aleksandra V.
AU  - Lolić, Aleksandar
AU  - Baošić, Rada
PY  - 2015
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1894
AB  - The lipophilic character of polydentate Schiff bases was investigated by reversed-phase thin-layer chromatography. In order to determine retention parameter as a measure of the lipophilicity of the tested compounds, three different binary solvent systems, composed of water and organic modifier (methanol, acetonitrile, and tetrahydrofuran), were used. Lipophilicity parameters together with 2D molecular descriptors were subjected to the multivariate statistical analysis. Principal component analysis was employed to reveal the most influential factors governing the lipophilicity of the investigated compounds. Finally, the influence of organic modifier on determination of lipophilicity parameters was discussed.
PB  - Springer Wien, Wien
T2  - Monatshefte Fur Chemie
T1  - Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases
VL  - 146
IS  - 1
SP  - 1
EP  - 6
DO  - 10.1007/s00706-014-1313-7
ER  - 

@article{
author = "Perušković, Danica S. and Daric, Branka and Blagus, Anita and Stevanović, Nikola R. and Pavlović, Aleksandra V. and Lolić, Aleksandar and Baošić, Rada",
year = "2015",
abstract = "The lipophilic character of polydentate Schiff bases was investigated by reversed-phase thin-layer chromatography. In order to determine retention parameter as a measure of the lipophilicity of the tested compounds, three different binary solvent systems, composed of water and organic modifier (methanol, acetonitrile, and tetrahydrofuran), were used. Lipophilicity parameters together with 2D molecular descriptors were subjected to the multivariate statistical analysis. Principal component analysis was employed to reveal the most influential factors governing the lipophilicity of the investigated compounds. Finally, the influence of organic modifier on determination of lipophilicity parameters was discussed.",
publisher = "Springer Wien, Wien",
journal = "Monatshefte Fur Chemie",
title = "Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases",
volume = "146",
number = "1",
pages = "1-6",
doi = "10.1007/s00706-014-1313-7"
}

Perušković, D. S., Daric, B., Blagus, A., Stevanović, N. R., Pavlović, A. V., Lolić, A.,& Baošić, R.. (2015). Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases. in Monatshefte Fur Chemie
Springer Wien, Wien., 146(1), 1-6.
https://doi.org/10.1007/s00706-014-1313-7

Perušković DS, Daric B, Blagus A, Stevanović NR, Pavlović AV, Lolić A, Baošić R. Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases. in Monatshefte Fur Chemie. 2015;146(1):1-6.
doi:10.1007/s00706-014-1313-7 .

Perušković, Danica S., Daric, Branka, Blagus, Anita, Stevanović, Nikola R., Pavlović, Aleksandra V., Lolić, Aleksandar, Baošić, Rada, "Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases" in Monatshefte Fur Chemie, 146, no. 1 (2015):1-6,
https://doi.org/10.1007/s00706-014-1313-7 . .

TY  - JOUR
AU  - Perušković, Danica S.
AU  - Stevanović, Nikola R.
AU  - Lolić, Aleksandar
AU  - Nikolić, Milan
AU  - Baošić, Rada
PY  - 2014
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4950
AB  - The retention behavior and lipophilicity parameters of some antiphychotics were determined using reversed-phase thin layer chromatography. Quantitative structure-activity relationships studies have been performed to correlate the molecular characteristics of observed compounds with their retention as well as with their chromatographically determinated lipophilicity parameters.
The effect of different organic modifiers (acetone, tetrahydrofuran, and methanol) has been studied. The retention of investigated compounds decreases linearly with increasing concentration of organic modifier. The chemical structures of the antipsychotics have been characterized by molecular descriptors which are calculated from the structure and related to chromatographically determinated lipophilicity parameters by multiple linear regression analysis. This approach gives us the possibility to gain insight into factors responsible for the retention as well as lipophilicity of the investigated set of the compounds. The most prominent factors affecting lipophilicity of the investigated substances are Solubility, Energy of the highest occupied molecular orbital, and Energy of the lowest unoccupied molecular orbital. The obtained models were used for interpretation of the lipophilicity of the investigated compounds. The prediction results are in good agreement with the experimental value. This study provides good information about pharmacologically important physico-chemical parameters of observed antipsychotics relevant to variations in molecular lipophilicity and chromatographic behavior. Established QSAR models could be helpful in design of novel multitarget antipsychotic compounds.
PB  - Scientific Research Publishing
T2  - American Journal of Analytical Chemistry
T1  - Quantitative Structure-Activity Relationship Study of Some Antipsychotics by Multiple Linear Regressions
VL  - 5
IS  - 5
SP  - 335
EP  - 342
DO  - 10.4236/ajac.2014.55041
ER  - 

@article{
author = "Perušković, Danica S. and Stevanović, Nikola R. and Lolić, Aleksandar and Nikolić, Milan and Baošić, Rada",
year = "2014",
abstract = "The retention behavior and lipophilicity parameters of some antiphychotics were determined using reversed-phase thin layer chromatography. Quantitative structure-activity relationships studies have been performed to correlate the molecular characteristics of observed compounds with their retention as well as with their chromatographically determinated lipophilicity parameters.
The effect of different organic modifiers (acetone, tetrahydrofuran, and methanol) has been studied. The retention of investigated compounds decreases linearly with increasing concentration of organic modifier. The chemical structures of the antipsychotics have been characterized by molecular descriptors which are calculated from the structure and related to chromatographically determinated lipophilicity parameters by multiple linear regression analysis. This approach gives us the possibility to gain insight into factors responsible for the retention as well as lipophilicity of the investigated set of the compounds. The most prominent factors affecting lipophilicity of the investigated substances are Solubility, Energy of the highest occupied molecular orbital, and Energy of the lowest unoccupied molecular orbital. The obtained models were used for interpretation of the lipophilicity of the investigated compounds. The prediction results are in good agreement with the experimental value. This study provides good information about pharmacologically important physico-chemical parameters of observed antipsychotics relevant to variations in molecular lipophilicity and chromatographic behavior. Established QSAR models could be helpful in design of novel multitarget antipsychotic compounds.",
publisher = "Scientific Research Publishing",
journal = "American Journal of Analytical Chemistry",
title = "Quantitative Structure-Activity Relationship Study of Some Antipsychotics by Multiple Linear Regressions",
volume = "5",
number = "5",
pages = "335-342",
doi = "10.4236/ajac.2014.55041"
}

Perušković, D. S., Stevanović, N. R., Lolić, A., Nikolić, M.,& Baošić, R.. (2014). Quantitative Structure-Activity Relationship Study of Some Antipsychotics by Multiple Linear Regressions. in American Journal of Analytical Chemistry
Scientific Research Publishing., 5(5), 335-342.
https://doi.org/10.4236/ajac.2014.55041

Perušković DS, Stevanović NR, Lolić A, Nikolić M, Baošić R. Quantitative Structure-Activity Relationship Study of Some Antipsychotics by Multiple Linear Regressions. in American Journal of Analytical Chemistry. 2014;5(5):335-342.
doi:10.4236/ajac.2014.55041 .

Perušković, Danica S., Stevanović, Nikola R., Lolić, Aleksandar, Nikolić, Milan, Baošić, Rada, "Quantitative Structure-Activity Relationship Study of Some Antipsychotics by Multiple Linear Regressions" in American Journal of Analytical Chemistry, 5, no. 5 (2014):335-342,
https://doi.org/10.4236/ajac.2014.55041 . .

TY  - CONF
AU  - Perušković, Danica S.
AU  - Stevanović, Nikola R.
AU  - Lolić, Aleksandar
AU  - Mandić, Snežana
AU  - Baošić, Rada
PY  - 2014
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4993
AB  - Schiff bases play an important role in inorganic chemistry as they easily form stable complexes
with majority of transition metal ions. Complexes of Schiff bases have been recognized as
models for biologically important species. The aim of this work is to investigate chromatographic
behaviour of series of 12 tetradentate Schiff bases and corresponding copper(II) and
nickel(II) complexes by normal- and reversed-phase thin layer chromatography, and optimization
of chromatographic conditions for their separation. Chromatographic methods have been
frequently applied for determination of retention parameter (RM), which is used for quantitative
relationships between chemical structure and retention. The chemical structures of investigated
compounds can be characterized by molecular descriptors. Quantitative structure-retention relationship
(QSRR) describes how molecular structure affects chromatographic retention. In the case
of thin layer chromatography, the QSRR studies are usually based on RM value, which is defined
by Bate-Smith and Westall eguation. In this study we used two stationary and twenty two
mobile phases. Also, in this work we used multivariant regression analysis to confirm the optimal
chromatographic conditions.
C3  - 9th Aegean Analytical Chemistry Days, 29 Sept-03 Oct 2014, Chios, Greece, Book of Abstracts, P4-09
T1  - Chromatographic behaviour of tetradentate Schiff base and corresponding Copper(II) and Nickel(II) complexes by NP- and RP-TLC
SP  - 193
EP  - 193
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4993
ER  - 

@conference{
author = "Perušković, Danica S. and Stevanović, Nikola R. and Lolić, Aleksandar and Mandić, Snežana and Baošić, Rada",
year = "2014",
abstract = "Schiff bases play an important role in inorganic chemistry as they easily form stable complexes
with majority of transition metal ions. Complexes of Schiff bases have been recognized as
models for biologically important species. The aim of this work is to investigate chromatographic
behaviour of series of 12 tetradentate Schiff bases and corresponding copper(II) and
nickel(II) complexes by normal- and reversed-phase thin layer chromatography, and optimization
of chromatographic conditions for their separation. Chromatographic methods have been
frequently applied for determination of retention parameter (RM), which is used for quantitative
relationships between chemical structure and retention. The chemical structures of investigated
compounds can be characterized by molecular descriptors. Quantitative structure-retention relationship
(QSRR) describes how molecular structure affects chromatographic retention. In the case
of thin layer chromatography, the QSRR studies are usually based on RM value, which is defined
by Bate-Smith and Westall eguation. In this study we used two stationary and twenty two
mobile phases. Also, in this work we used multivariant regression analysis to confirm the optimal
chromatographic conditions.",
journal = "9th Aegean Analytical Chemistry Days, 29 Sept-03 Oct 2014, Chios, Greece, Book of Abstracts, P4-09",
title = "Chromatographic behaviour of tetradentate Schiff base and corresponding Copper(II) and Nickel(II) complexes by NP- and RP-TLC",
pages = "193-193",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4993"
}

Perušković, D. S., Stevanović, N. R., Lolić, A., Mandić, S.,& Baošić, R.. (2014). Chromatographic behaviour of tetradentate Schiff base and corresponding Copper(II) and Nickel(II) complexes by NP- and RP-TLC. in 9th Aegean Analytical Chemistry Days, 29 Sept-03 Oct 2014, Chios, Greece, Book of Abstracts, P4-09, 193-193.
https://hdl.handle.net/21.15107/rcub_cherry_4993

Perušković DS, Stevanović NR, Lolić A, Mandić S, Baošić R. Chromatographic behaviour of tetradentate Schiff base and corresponding Copper(II) and Nickel(II) complexes by NP- and RP-TLC. in 9th Aegean Analytical Chemistry Days, 29 Sept-03 Oct 2014, Chios, Greece, Book of Abstracts, P4-09. 2014;:193-193.
https://hdl.handle.net/21.15107/rcub_cherry_4993 .

Perušković, Danica S., Stevanović, Nikola R., Lolić, Aleksandar, Mandić, Snežana, Baošić, Rada, "Chromatographic behaviour of tetradentate Schiff base and corresponding Copper(II) and Nickel(II) complexes by NP- and RP-TLC" in 9th Aegean Analytical Chemistry Days, 29 Sept-03 Oct 2014, Chios, Greece, Book of Abstracts, P4-09 (2014):193-193,
https://hdl.handle.net/21.15107/rcub_cherry_4993 .

TY  - JOUR
AU  - Perušković, Danica S.
AU  - Stevanović, Nikola R.
AU  - Lolić, Aleksandar
AU  - Baošić, Rada
PY  - 2014
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1508
AB  - The objectives of this study were to gain insights into the structure-retention and structure-lipophilicity relationships of series of twenty antidepressants and to propose model for estimating their retention and lipophilicity. The lipophilicity of antidepressants has been determined by reversed-phase thin-layer chromatography using binary methanol-water mobile phases. The chemical structures of the antidepressants have been characterized by molecular descriptors which are calculated from the structure and related to the chromatographic retention parameters as well as chromatographically determinated lipophilicity parameters by multiple linear regression analysis. The obtained models were used for interpretation of the lipophilicity and retention behavior of the investigated compounds.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Letters in Drug Design and Discovery
T1  - Correlation Between Structure, Retention and Lipophilicity of Some Antidepressants: QSRR and QSAR Studies
VL  - 11
IS  - 2
SP  - 162
EP  - 168
UR  - https://hdl.handle.net/21.15107/rcub_cherry_1508
ER  - 

@article{
author = "Perušković, Danica S. and Stevanović, Nikola R. and Lolić, Aleksandar and Baošić, Rada",
year = "2014",
abstract = "The objectives of this study were to gain insights into the structure-retention and structure-lipophilicity relationships of series of twenty antidepressants and to propose model for estimating their retention and lipophilicity. The lipophilicity of antidepressants has been determined by reversed-phase thin-layer chromatography using binary methanol-water mobile phases. The chemical structures of the antidepressants have been characterized by molecular descriptors which are calculated from the structure and related to the chromatographic retention parameters as well as chromatographically determinated lipophilicity parameters by multiple linear regression analysis. The obtained models were used for interpretation of the lipophilicity and retention behavior of the investigated compounds.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Letters in Drug Design and Discovery",
title = "Correlation Between Structure, Retention and Lipophilicity of Some Antidepressants: QSRR and QSAR Studies",
volume = "11",
number = "2",
pages = "162-168",
url = "https://hdl.handle.net/21.15107/rcub_cherry_1508"
}

Perušković, D. S., Stevanović, N. R., Lolić, A.,& Baošić, R.. (2014). Correlation Between Structure, Retention and Lipophilicity of Some Antidepressants: QSRR and QSAR Studies. in Letters in Drug Design and Discovery
Bentham Science Publ Ltd, Sharjah., 11(2), 162-168.
https://hdl.handle.net/21.15107/rcub_cherry_1508

Perušković DS, Stevanović NR, Lolić A, Baošić R. Correlation Between Structure, Retention and Lipophilicity of Some Antidepressants: QSRR and QSAR Studies. in Letters in Drug Design and Discovery. 2014;11(2):162-168.
https://hdl.handle.net/21.15107/rcub_cherry_1508 .

Perušković, Danica S., Stevanović, Nikola R., Lolić, Aleksandar, Baošić, Rada, "Correlation Between Structure, Retention and Lipophilicity of Some Antidepressants: QSRR and QSAR Studies" in Letters in Drug Design and Discovery, 11, no. 2 (2014):162-168,
https://hdl.handle.net/21.15107/rcub_cherry_1508 .