TY  - JOUR
AU  - Jadranin, Milka
AU  - Savić, Danica
AU  - Lupšić, Ema
AU  - Podolski-Renić, Ana
AU  - Pešić, Milica
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan M.
AU  - Krstić, Gordana B.
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6432
AB  - Euphorbia seguieriana ssp. seguieriana Necker (ES) and Euphorbia cyparissias (EC) with a habitat in the Deliblato Sands were the subject of this examination. The latexes of these so far insufficiently investigated species of the Euphorbia genus are used in traditional medicine for the treatment of wounds and warts on the skin. To determine their chemical composition, non-targeted screening of the latexes’ chloroform extracts was performed using liquid chromatography coupled with quadrupole time-of-flight mass spectrometry employing an electrospray ionization source (LC-ESI QTOF MS). The analysis of the obtained results showed that the latexes of ES and EC represent rich sources of diterpenes, tentatively identified as jatrophanes, ingenanes, tiglianes, myrsinanes, premyrsinanes, and others. Examination of the anticancer activity of the ES and EC latex extracts showed that both extracts significantly inhibited the growth of the non-small cell lung carcinoma NCI-H460 and glioblastoma U87 cell lines as well as of their corresponding multi-drug resistant (MDR) cell lines, NCI-H460/R and U87-TxR. The obtained results also revealed that the ES and EC extracts inhibited the function of P-glycoprotein (P-gp) in MDR cancer cells, whose overexpression is one of the main mechanisms underlying MDR.
PB  - MDPI
T2  - Plants
T1  - LC-ESI QToF MS Non-Targeted Screening of Latex Extracts of Euphorbia seguieriana ssp. seguieriana Necker and Euphorbia cyparissias and Determination of Their Potential Anticancer Activity
VL  - 12
IS  - 24
SP  - 4181
DO  - 10.3390/plants12244181
ER  - 

@article{
author = "Jadranin, Milka and Savić, Danica and Lupšić, Ema and Podolski-Renić, Ana and Pešić, Milica and Tešević, Vele and Milosavljević, Slobodan M. and Krstić, Gordana B.",
year = "2023",
abstract = "Euphorbia seguieriana ssp. seguieriana Necker (ES) and Euphorbia cyparissias (EC) with a habitat in the Deliblato Sands were the subject of this examination. The latexes of these so far insufficiently investigated species of the Euphorbia genus are used in traditional medicine for the treatment of wounds and warts on the skin. To determine their chemical composition, non-targeted screening of the latexes’ chloroform extracts was performed using liquid chromatography coupled with quadrupole time-of-flight mass spectrometry employing an electrospray ionization source (LC-ESI QTOF MS). The analysis of the obtained results showed that the latexes of ES and EC represent rich sources of diterpenes, tentatively identified as jatrophanes, ingenanes, tiglianes, myrsinanes, premyrsinanes, and others. Examination of the anticancer activity of the ES and EC latex extracts showed that both extracts significantly inhibited the growth of the non-small cell lung carcinoma NCI-H460 and glioblastoma U87 cell lines as well as of their corresponding multi-drug resistant (MDR) cell lines, NCI-H460/R and U87-TxR. The obtained results also revealed that the ES and EC extracts inhibited the function of P-glycoprotein (P-gp) in MDR cancer cells, whose overexpression is one of the main mechanisms underlying MDR.",
publisher = "MDPI",
journal = "Plants",
title = "LC-ESI QToF MS Non-Targeted Screening of Latex Extracts of Euphorbia seguieriana ssp. seguieriana Necker and Euphorbia cyparissias and Determination of Their Potential Anticancer Activity",
volume = "12",
number = "24",
pages = "4181",
doi = "10.3390/plants12244181"
}

Jadranin, M., Savić, D., Lupšić, E., Podolski-Renić, A., Pešić, M., Tešević, V., Milosavljević, S. M.,& Krstić, G. B.. (2023). LC-ESI QToF MS Non-Targeted Screening of Latex Extracts of Euphorbia seguieriana ssp. seguieriana Necker and Euphorbia cyparissias and Determination of Their Potential Anticancer Activity. in Plants
MDPI., 12(24), 4181.
https://doi.org/10.3390/plants12244181

Jadranin M, Savić D, Lupšić E, Podolski-Renić A, Pešić M, Tešević V, Milosavljević SM, Krstić GB. LC-ESI QToF MS Non-Targeted Screening of Latex Extracts of Euphorbia seguieriana ssp. seguieriana Necker and Euphorbia cyparissias and Determination of Their Potential Anticancer Activity. in Plants. 2023;12(24):4181.
doi:10.3390/plants12244181 .

Jadranin, Milka, Savić, Danica, Lupšić, Ema, Podolski-Renić, Ana, Pešić, Milica, Tešević, Vele, Milosavljević, Slobodan M., Krstić, Gordana B., "LC-ESI QToF MS Non-Targeted Screening of Latex Extracts of Euphorbia seguieriana ssp. seguieriana Necker and Euphorbia cyparissias and Determination of Their Potential Anticancer Activity" in Plants, 12, no. 24 (2023):4181,
https://doi.org/10.3390/plants12244181 . .

TY  - JOUR
AU  - Novaković, Miroslav M.
AU  - Todorović, Nina
AU  - Jadranin, Milka
AU  - Đorđević, Iris
AU  - Milosavljević, Slobodan M.
AU  - Mandić, Boris
AU  - Tešević, Vele
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6264
AB  - A new auronolignan, named cotinignan B, was isolated from Cotinus coggygria Scop. Structure elucidation was performed on the basis of 1H, 13C NMR, COSY, NOESY, HSQC, and HMBC experiments, supported with HR-ESI-MS, IR and UV. Additional J-HMBC NMR experiment was essential to resolve the configuration of the trisubstituted double bond. This compound represents the secondly discovered natural compound belonging to the rare auronolignan type.
PB  - Springer
T2  - Chemistry of Natural Compounds
T1  - A New Auronolignan from the Cotinus coggygria Heartwood
VL  - 59
IS  - 3
SP  - 428
EP  - 430
DO  - 10.1007/s10600-023-04016-5
ER  - 

@article{
author = "Novaković, Miroslav M. and Todorović, Nina and Jadranin, Milka and Đorđević, Iris and Milosavljević, Slobodan M. and Mandić, Boris and Tešević, Vele",
year = "2023",
abstract = "A new auronolignan, named cotinignan B, was isolated from Cotinus coggygria Scop. Structure elucidation was performed on the basis of 1H, 13C NMR, COSY, NOESY, HSQC, and HMBC experiments, supported with HR-ESI-MS, IR and UV. Additional J-HMBC NMR experiment was essential to resolve the configuration of the trisubstituted double bond. This compound represents the secondly discovered natural compound belonging to the rare auronolignan type.",
publisher = "Springer",
journal = "Chemistry of Natural Compounds",
title = "A New Auronolignan from the Cotinus coggygria Heartwood",
volume = "59",
number = "3",
pages = "428-430",
doi = "10.1007/s10600-023-04016-5"
}

Novaković, M. M., Todorović, N., Jadranin, M., Đorđević, I., Milosavljević, S. M., Mandić, B.,& Tešević, V.. (2023). A New Auronolignan from the Cotinus coggygria Heartwood. in Chemistry of Natural Compounds
Springer., 59(3), 428-430.
https://doi.org/10.1007/s10600-023-04016-5

Novaković MM, Todorović N, Jadranin M, Đorđević I, Milosavljević SM, Mandić B, Tešević V. A New Auronolignan from the Cotinus coggygria Heartwood. in Chemistry of Natural Compounds. 2023;59(3):428-430.
doi:10.1007/s10600-023-04016-5 .

Novaković, Miroslav M., Todorović, Nina, Jadranin, Milka, Đorđević, Iris, Milosavljević, Slobodan M., Mandić, Boris, Tešević, Vele, "A New Auronolignan from the Cotinus coggygria Heartwood" in Chemistry of Natural Compounds, 59, no. 3 (2023):428-430,
https://doi.org/10.1007/s10600-023-04016-5 . .

TY  - JOUR
AU  - Jadranin, Milka
AU  - Avramović, Nataša
AU  - Miladinović, Zoran P.
AU  - Gavrilović, Aleksandra
AU  - Tasic, Ljubica
AU  - Tešević, Vele
AU  - Mandić, Boris
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6391
AB  - The Lipidomic profiles of serum samples from patients with bipolar disorder (BD) and healthy controls (C) were explored and compared. The sample cohort included 31 BD patients and 31 control individuals. An untargeted lipidomics study applying liquid chromatography (LC) coupled with high-resolution mass spectrometry (HRMS) was conducted to achieve the lipid profiles. Multivariate statistical analyses (principal component analysis and partial least squares discriminant analysis) were performed, and fifty-six differential lipids were confirmed in BD and controls. Our results pointed to alterations in lipid metabolism, including pathways of glycerophospholipids, sphingolipids, glycerolipids, and sterol lipids, in BD patient sera. This study emphasized the role of lipid pathways in BD, and comprehensive research using the LC-HRMS platform is necessary for future application in the diagnosis and improvement of BD treatments.
PB  - MDPI
T2  - International Journal of Molecular Sciences
T1  - Untargeted Lipidomics Study of Bipolar Disorder Patients in Serbia
VL  - 24
IS  - 22
SP  - 16025
DO  - 10.3390/ijms242216025
ER  - 

@article{
author = "Jadranin, Milka and Avramović, Nataša and Miladinović, Zoran P. and Gavrilović, Aleksandra and Tasic, Ljubica and Tešević, Vele and Mandić, Boris",
year = "2023",
abstract = "The Lipidomic profiles of serum samples from patients with bipolar disorder (BD) and healthy controls (C) were explored and compared. The sample cohort included 31 BD patients and 31 control individuals. An untargeted lipidomics study applying liquid chromatography (LC) coupled with high-resolution mass spectrometry (HRMS) was conducted to achieve the lipid profiles. Multivariate statistical analyses (principal component analysis and partial least squares discriminant analysis) were performed, and fifty-six differential lipids were confirmed in BD and controls. Our results pointed to alterations in lipid metabolism, including pathways of glycerophospholipids, sphingolipids, glycerolipids, and sterol lipids, in BD patient sera. This study emphasized the role of lipid pathways in BD, and comprehensive research using the LC-HRMS platform is necessary for future application in the diagnosis and improvement of BD treatments.",
publisher = "MDPI",
journal = "International Journal of Molecular Sciences",
title = "Untargeted Lipidomics Study of Bipolar Disorder Patients in Serbia",
volume = "24",
number = "22",
pages = "16025",
doi = "10.3390/ijms242216025"
}

Jadranin, M., Avramović, N., Miladinović, Z. P., Gavrilović, A., Tasic, L., Tešević, V.,& Mandić, B.. (2023). Untargeted Lipidomics Study of Bipolar Disorder Patients in Serbia. in International Journal of Molecular Sciences
MDPI., 24(22), 16025.
https://doi.org/10.3390/ijms242216025

Jadranin M, Avramović N, Miladinović ZP, Gavrilović A, Tasic L, Tešević V, Mandić B. Untargeted Lipidomics Study of Bipolar Disorder Patients in Serbia. in International Journal of Molecular Sciences. 2023;24(22):16025.
doi:10.3390/ijms242216025 .

Jadranin, Milka, Avramović, Nataša, Miladinović, Zoran P., Gavrilović, Aleksandra, Tasic, Ljubica, Tešević, Vele, Mandić, Boris, "Untargeted Lipidomics Study of Bipolar Disorder Patients in Serbia" in International Journal of Molecular Sciences, 24, no. 22 (2023):16025,
https://doi.org/10.3390/ijms242216025 . .

TY  - JOUR
AU  - Ivanović, Stefan
AU  - Simić, Katarina
AU  - Lekić, Stefan
AU  - Jadranin, Milka
AU  - Vujisić, Ljubodrag V.
AU  - Gođevac, Dejan
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5655
AB  - Allium ursinum and poisonous adulterants Convallaria majalis and Arum maculatum were used as a model for detection of adulterants in edible plant. A. ursinum samples were spiked with C. majalis and A. maculatum to mimic adulteration. Metabolomic fingerprinting of all samples was performed using 1H NMR spectroscopy, and the resulting data sets were subjected to multivariate data analysis. As a result of this analysis, signals of adulterants were extracted from the data, and the structures of biomarkers of adulteration from partially purified samples were elucidated using 2D NMR and LC-MS techniques. Thus, isovitexin and vicenin II, azetidine-2-carboxylic acid, and trigonelline indicated adulteration of A. ursinum samples with C. majalis. Isovitexin was also recognized to be an indicator of adulteration of A. ursinum with A. maculatum. In conclusion, the case study of A. ursinum suggested that plant metabolomics approach could be utilized for identification of low molecular weight biomarkers of adulteration in edible plants. © 2022 by the authors.
PB  - MDPI
T2  - Metabolites
T1  - Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum
VL  - 12
SP  - 849
DO  - 10.3390/metabo12090849
ER  - 

@article{
author = "Ivanović, Stefan and Simić, Katarina and Lekić, Stefan and Jadranin, Milka and Vujisić, Ljubodrag V. and Gođevac, Dejan",
year = "2022",
abstract = "Allium ursinum and poisonous adulterants Convallaria majalis and Arum maculatum were used as a model for detection of adulterants in edible plant. A. ursinum samples were spiked with C. majalis and A. maculatum to mimic adulteration. Metabolomic fingerprinting of all samples was performed using 1H NMR spectroscopy, and the resulting data sets were subjected to multivariate data analysis. As a result of this analysis, signals of adulterants were extracted from the data, and the structures of biomarkers of adulteration from partially purified samples were elucidated using 2D NMR and LC-MS techniques. Thus, isovitexin and vicenin II, azetidine-2-carboxylic acid, and trigonelline indicated adulteration of A. ursinum samples with C. majalis. Isovitexin was also recognized to be an indicator of adulteration of A. ursinum with A. maculatum. In conclusion, the case study of A. ursinum suggested that plant metabolomics approach could be utilized for identification of low molecular weight biomarkers of adulteration in edible plants. © 2022 by the authors.",
publisher = "MDPI",
journal = "Metabolites",
title = "Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum",
volume = "12",
pages = "849",
doi = "10.3390/metabo12090849"
}

Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L. V.,& Gođevac, D.. (2022). Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites
MDPI., 12, 849.
https://doi.org/10.3390/metabo12090849

Ivanović S, Simić K, Lekić S, Jadranin M, Vujisić LV, Gođevac D. Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites. 2022;12:849.
doi:10.3390/metabo12090849 .

Ivanović, Stefan, Simić, Katarina, Lekić, Stefan, Jadranin, Milka, Vujisić, Ljubodrag V., Gođevac, Dejan, "Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum" in Metabolites, 12 (2022):849,
https://doi.org/10.3390/metabo12090849 . .

TY  - DATA
AU  - Ivanović, Stefan
AU  - Simić, Katarina
AU  - Lekić, Stefan
AU  - Jadranin, Milka
AU  - Vujisić, Ljubodrag V.
AU  - Gođevac, Dejan
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5660
AB  - Allium ursinum and poisonous adulterants Convallaria majalis and Arum maculatum were used as a model for detection of adulterants in edible plant. A. ursinum samples were spiked with C. majalis and A. maculatum to mimic adulteration. Metabolomic fingerprinting of all samples was performed using 1H NMR spectroscopy, and the resulting data sets were subjected to multivariate data analysis. As a result of this analysis, signals of adulterants were extracted from the data, and the structures of biomarkers of adulteration from partially purified samples were elucidated using 2D NMR and LC-MS techniques. Thus, isovitexin and vicenin II, azetidine-2-carboxylic acid, and trigonelline indicated adulteration of A. ursinum samples with C. majalis. Isovitexin was also recognized to be an indicator of adulteration of A. ursinum with A. maculatum. In conclusion, the case study of A. ursinum suggested that plant metabolomics approach could be utilized for identification of low molecular weight biomarkers of adulteration in edible plants. © 2022 by the authors.
PB  - MDPI
T2  - Metabolites
T1  - Supplementary material for: Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L.,& Gođevac, D.. (2022). Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites MDPI., 12, 849. https://doi.org/10.3390/metabo12090849
VL  - 12
SP  - 849
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5660
ER  - 

@misc{
author = "Ivanović, Stefan and Simić, Katarina and Lekić, Stefan and Jadranin, Milka and Vujisić, Ljubodrag V. and Gođevac, Dejan",
year = "2022",
abstract = "Allium ursinum and poisonous adulterants Convallaria majalis and Arum maculatum were used as a model for detection of adulterants in edible plant. A. ursinum samples were spiked with C. majalis and A. maculatum to mimic adulteration. Metabolomic fingerprinting of all samples was performed using 1H NMR spectroscopy, and the resulting data sets were subjected to multivariate data analysis. As a result of this analysis, signals of adulterants were extracted from the data, and the structures of biomarkers of adulteration from partially purified samples were elucidated using 2D NMR and LC-MS techniques. Thus, isovitexin and vicenin II, azetidine-2-carboxylic acid, and trigonelline indicated adulteration of A. ursinum samples with C. majalis. Isovitexin was also recognized to be an indicator of adulteration of A. ursinum with A. maculatum. In conclusion, the case study of A. ursinum suggested that plant metabolomics approach could be utilized for identification of low molecular weight biomarkers of adulteration in edible plants. © 2022 by the authors.",
publisher = "MDPI",
journal = "Metabolites",
title = "Supplementary material for: Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L.,& Gođevac, D.. (2022). Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites MDPI., 12, 849. https://doi.org/10.3390/metabo12090849",
volume = "12",
pages = "849",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5660"
}

Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L. V.,& Gođevac, D.. (2022). Supplementary material for: Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L.,& Gođevac, D.. (2022). Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites MDPI., 12, 849. https://doi.org/10.3390/metabo12090849. in Metabolites
MDPI., 12, 849.
https://hdl.handle.net/21.15107/rcub_cherry_5660

Ivanović S, Simić K, Lekić S, Jadranin M, Vujisić LV, Gođevac D. Supplementary material for: Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L.,& Gođevac, D.. (2022). Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites MDPI., 12, 849. https://doi.org/10.3390/metabo12090849. in Metabolites. 2022;12:849.
https://hdl.handle.net/21.15107/rcub_cherry_5660 .

Ivanović, Stefan, Simić, Katarina, Lekić, Stefan, Jadranin, Milka, Vujisić, Ljubodrag V., Gođevac, Dejan, "Supplementary material for: Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L.,& Gođevac, D.. (2022). Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites MDPI., 12, 849. https://doi.org/10.3390/metabo12090849" in Metabolites, 12 (2022):849,
https://hdl.handle.net/21.15107/rcub_cherry_5660 .

TY  - JOUR
AU  - Đorđević, Iris
AU  - Cvetković, Mirjana
AU  - Jadranin, Milka
AU  - Bojović, Srđan R.
AU  - Anđelković, Boban D.
AU  - Sofrenić, Ivana V.
AU  - Simić, Katarina
PY  - 2021
UR  - http://www.doiserbia.nb.rs/Article.aspx?ID=0352-51392100083D
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4941
AB  - Phytochemistry deals with the study of secondary metabolites produced by plants that synthesize these compounds for many reasons, including their own protection against attack of herbivores and plant diseases. Secondary metabolites are believed to represent plant adaptation to various environmental factors and that they enabled the survival of the species. Secondary metabolites of plants can have curative or toxic effects in humans and animals. Herbal medicine has a long tradition in folk medicine and until the early 20th century, when synthetic organic chemistry began to develop, plants were the main source of medicines. The two basic goals of our phytochemical research are: isolation and identification of new (biologically active) compounds ? potential drugs, and chemotaxonomy (chemosystematics). In the following text through one selected example, the genus Amphoricarpos Vis., our phytochemical research is shown on both aspects.
PB  - Belgrade : Serbian Chemical Socitey
T2  - Journal of the Serbian Chemical Society
T1  - Phytochemical study of the genus Amphoricarpos
VL  - 86
IS  - 12
SP  - 1177
EP  - 1193
DO  - 10.2298/JSC210726083D
ER  - 

@article{
author = "Đorđević, Iris and Cvetković, Mirjana and Jadranin, Milka and Bojović, Srđan R. and Anđelković, Boban D. and Sofrenić, Ivana V. and Simić, Katarina",
year = "2021",
abstract = "Phytochemistry deals with the study of secondary metabolites produced by plants that synthesize these compounds for many reasons, including their own protection against attack of herbivores and plant diseases. Secondary metabolites are believed to represent plant adaptation to various environmental factors and that they enabled the survival of the species. Secondary metabolites of plants can have curative or toxic effects in humans and animals. Herbal medicine has a long tradition in folk medicine and until the early 20th century, when synthetic organic chemistry began to develop, plants were the main source of medicines. The two basic goals of our phytochemical research are: isolation and identification of new (biologically active) compounds ? potential drugs, and chemotaxonomy (chemosystematics). In the following text through one selected example, the genus Amphoricarpos Vis., our phytochemical research is shown on both aspects.",
publisher = "Belgrade : Serbian Chemical Socitey",
journal = "Journal of the Serbian Chemical Society",
title = "Phytochemical study of the genus Amphoricarpos",
volume = "86",
number = "12",
pages = "1177-1193",
doi = "10.2298/JSC210726083D"
}

Đorđević, I., Cvetković, M., Jadranin, M., Bojović, S. R., Anđelković, B. D., Sofrenić, I. V.,& Simić, K.. (2021). Phytochemical study of the genus Amphoricarpos. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Socitey., 86(12), 1177-1193.
https://doi.org/10.2298/JSC210726083D

Đorđević I, Cvetković M, Jadranin M, Bojović SR, Anđelković BD, Sofrenić IV, Simić K. Phytochemical study of the genus Amphoricarpos. in Journal of the Serbian Chemical Society. 2021;86(12):1177-1193.
doi:10.2298/JSC210726083D .

Đorđević, Iris, Cvetković, Mirjana, Jadranin, Milka, Bojović, Srđan R., Anđelković, Boban D., Sofrenić, Ivana V., Simić, Katarina, "Phytochemical study of the genus Amphoricarpos" in Journal of the Serbian Chemical Society, 86, no. 12 (2021):1177-1193,
https://doi.org/10.2298/JSC210726083D . .

TY  - JOUR
AU  - Milosavljević, Saša
AU  - Jadranin, Milka
AU  - Mladenović, Mića
AU  - Tešević, Vele
AU  - Menković, Nebojša
AU  - Mutavdžić, Dragosav
AU  - Krstić, Gordana B.
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4624
AB  - The aim of this research was to verify the authenticity of monofloral honeys from the territory of the Republic of Serbia on the basis of physicochemical parameters routinely measured in honey quality control using multivariate analysis. Seventeen samples of monofloral honey (11 samples of acacia honey and 6 samples of sunflower honey) from the territory of the Republic of Serbia were analyzed. Physicochemical analysis of the samples included the examination of basic quality parameters and qualitative and quantitative analyses of phenolic compounds. In the samples tested, a total of 93 phenolic compounds were tentatively identified, and 19 of them were quantified. The obtained physicochemical analysis of the data served as input for the multivariate analysis. The hеаt map, which is useful for visualizing numerical data, was used for this purpose. The obtained results showed that the applied data can serve to clearly separate acacia and sunflower honeys.
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Physicochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia
VL  - 40
IS  - 1
SP  - 57
EP  - 67
DO  - 10.20450/mjcce.2021.2186
ER  - 

@article{
author = "Milosavljević, Saša and Jadranin, Milka and Mladenović, Mića and Tešević, Vele and Menković, Nebojša and Mutavdžić, Dragosav and Krstić, Gordana B.",
year = "2021",
abstract = "The aim of this research was to verify the authenticity of monofloral honeys from the territory of the Republic of Serbia on the basis of physicochemical parameters routinely measured in honey quality control using multivariate analysis. Seventeen samples of monofloral honey (11 samples of acacia honey and 6 samples of sunflower honey) from the territory of the Republic of Serbia were analyzed. Physicochemical analysis of the samples included the examination of basic quality parameters and qualitative and quantitative analyses of phenolic compounds. In the samples tested, a total of 93 phenolic compounds were tentatively identified, and 19 of them were quantified. The obtained physicochemical analysis of the data served as input for the multivariate analysis. The hеаt map, which is useful for visualizing numerical data, was used for this purpose. The obtained results showed that the applied data can serve to clearly separate acacia and sunflower honeys.",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Physicochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia",
volume = "40",
number = "1",
pages = "57-67",
doi = "10.20450/mjcce.2021.2186"
}

Milosavljević, S., Jadranin, M., Mladenović, M., Tešević, V., Menković, N., Mutavdžić, D.,& Krstić, G. B.. (2021). Physicochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia. in Macedonian Journal of Chemistry and Chemical Engineering, 40(1), 57-67.
https://doi.org/10.20450/mjcce.2021.2186

Milosavljević S, Jadranin M, Mladenović M, Tešević V, Menković N, Mutavdžić D, Krstić GB. Physicochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia. in Macedonian Journal of Chemistry and Chemical Engineering. 2021;40(1):57-67.
doi:10.20450/mjcce.2021.2186 .

Milosavljević, Saša, Jadranin, Milka, Mladenović, Mića, Tešević, Vele, Menković, Nebojša, Mutavdžić, Dragosav, Krstić, Gordana B., "Physicochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia" in Macedonian Journal of Chemistry and Chemical Engineering, 40, no. 1 (2021):57-67,
https://doi.org/10.20450/mjcce.2021.2186 . .

TY  - DATA
AU  - Topalović, Ana
AU  - Bogdanović, Višnja
AU  - Đurović, Dijana
AU  - Mugoša, Boban
AU  - Jadranin, Milka
AU  - Tešević, Vele
AU  - Beškoski, Vladimir
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4830
PB  - Emerald Publishing Limited
T2  - British Food Journal
T1  - Supplementary data for the article: Ivanović, L.; Topalović, A.; Bogdanović, V.; Đurović, D.; Mugoša, B.; Jadranin, M.; Tešević, V.; Beškoski, V. Antiproliferative Activity and Antioxidative Potential of Swiss Chard from Montenegro, Grown under Different Irrigation and Fertilization Regimes. British Food Journal 2021, 123 (7), 2335–2348. https://doi.org/10.1108/BFJ-11-2020-1062.
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4830
ER  - 

@misc{
author = "Topalović, Ana and Bogdanović, Višnja and Đurović, Dijana and Mugoša, Boban and Jadranin, Milka and Tešević, Vele and Beškoski, Vladimir",
year = "2021",
publisher = "Emerald Publishing Limited",
journal = "British Food Journal",
title = "Supplementary data for the article: Ivanović, L.; Topalović, A.; Bogdanović, V.; Đurović, D.; Mugoša, B.; Jadranin, M.; Tešević, V.; Beškoski, V. Antiproliferative Activity and Antioxidative Potential of Swiss Chard from Montenegro, Grown under Different Irrigation and Fertilization Regimes. British Food Journal 2021, 123 (7), 2335–2348. https://doi.org/10.1108/BFJ-11-2020-1062.",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4830"
}

Topalović, A., Bogdanović, V., Đurović, D., Mugoša, B., Jadranin, M., Tešević, V.,& Beškoski, V.. (2021). Supplementary data for the article: Ivanović, L.; Topalović, A.; Bogdanović, V.; Đurović, D.; Mugoša, B.; Jadranin, M.; Tešević, V.; Beškoski, V. Antiproliferative Activity and Antioxidative Potential of Swiss Chard from Montenegro, Grown under Different Irrigation and Fertilization Regimes. British Food Journal 2021, 123 (7), 2335–2348. https://doi.org/10.1108/BFJ-11-2020-1062.. in British Food Journal
Emerald Publishing Limited..
https://hdl.handle.net/21.15107/rcub_cherry_4830

Topalović A, Bogdanović V, Đurović D, Mugoša B, Jadranin M, Tešević V, Beškoski V. Supplementary data for the article: Ivanović, L.; Topalović, A.; Bogdanović, V.; Đurović, D.; Mugoša, B.; Jadranin, M.; Tešević, V.; Beškoski, V. Antiproliferative Activity and Antioxidative Potential of Swiss Chard from Montenegro, Grown under Different Irrigation and Fertilization Regimes. British Food Journal 2021, 123 (7), 2335–2348. https://doi.org/10.1108/BFJ-11-2020-1062.. in British Food Journal. 2021;.
https://hdl.handle.net/21.15107/rcub_cherry_4830 .

Topalović, Ana, Bogdanović, Višnja, Đurović, Dijana, Mugoša, Boban, Jadranin, Milka, Tešević, Vele, Beškoski, Vladimir, "Supplementary data for the article: Ivanović, L.; Topalović, A.; Bogdanović, V.; Đurović, D.; Mugoša, B.; Jadranin, M.; Tešević, V.; Beškoski, V. Antiproliferative Activity and Antioxidative Potential of Swiss Chard from Montenegro, Grown under Different Irrigation and Fertilization Regimes. British Food Journal 2021, 123 (7), 2335–2348. https://doi.org/10.1108/BFJ-11-2020-1062." in British Food Journal (2021),
https://hdl.handle.net/21.15107/rcub_cherry_4830 .

TY  - JOUR
AU  - Vučković, Ivan
AU  - Stiković, Sonja
AU  - Stešević, Danijela
AU  - Jadranin, Milka
AU  - Trifunović, Snežana S.
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5040
AB  - The plant species Pimpinella serbica (Vis.) Drude, endemic to West
Balkans, belongs to the genus Pimpinella L. (Apiaceae) according to newer
botanical classification. Initially, the plant was described as Pancicia serbica Vis.
and long considered as a monotypic genus. Previous phytochemical investigations
of this plant were limited to the essential oil analysis by the GC–MS method. This
is first study that includes LC-DAD–MS screening of the extracts of the roots and
aerial parts, followed by isolation of secondary metabolites using chromatographic
techniques. Five compounds belonging to phenylpropanoids and polyacetylenes,
well known for their bioactivities, were isolated and structurally determined by
combined spectroscopic methods (UV, NMR, MS). Dillapiole (1), nothoapiole (2)
and oplopantriol A 18-acetate (4) were found in both extracts, while falcarindiol (3)
was isolated from the roots and dendrotrifidol (5) from the aerial parts only. The
phytochemical profile of P. serbica L. supports its position in the Pimpinella L.
genus.
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Phytochemical investigation of Pimpinella serbica
VL  - 86
IS  - 12
SP  - 1241
EP  - 1247
DO  - 10.2298/JSC210816081V
ER  - 

@article{
author = "Vučković, Ivan and Stiković, Sonja and Stešević, Danijela and Jadranin, Milka and Trifunović, Snežana S.",
year = "2021",
abstract = "The plant species Pimpinella serbica (Vis.) Drude, endemic to West
Balkans, belongs to the genus Pimpinella L. (Apiaceae) according to newer
botanical classification. Initially, the plant was described as Pancicia serbica Vis.
and long considered as a monotypic genus. Previous phytochemical investigations
of this plant were limited to the essential oil analysis by the GC–MS method. This
is first study that includes LC-DAD–MS screening of the extracts of the roots and
aerial parts, followed by isolation of secondary metabolites using chromatographic
techniques. Five compounds belonging to phenylpropanoids and polyacetylenes,
well known for their bioactivities, were isolated and structurally determined by
combined spectroscopic methods (UV, NMR, MS). Dillapiole (1), nothoapiole (2)
and oplopantriol A 18-acetate (4) were found in both extracts, while falcarindiol (3)
was isolated from the roots and dendrotrifidol (5) from the aerial parts only. The
phytochemical profile of P. serbica L. supports its position in the Pimpinella L.
genus.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Phytochemical investigation of Pimpinella serbica",
volume = "86",
number = "12",
pages = "1241-1247",
doi = "10.2298/JSC210816081V"
}

Vučković, I., Stiković, S., Stešević, D., Jadranin, M.,& Trifunović, S. S.. (2021). Phytochemical investigation of Pimpinella serbica. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society., 86(12), 1241-1247.
https://doi.org/10.2298/JSC210816081V

Vučković I, Stiković S, Stešević D, Jadranin M, Trifunović SS. Phytochemical investigation of Pimpinella serbica. in Journal of the Serbian Chemical Society. 2021;86(12):1241-1247.
doi:10.2298/JSC210816081V .

Vučković, Ivan, Stiković, Sonja, Stešević, Danijela, Jadranin, Milka, Trifunović, Snežana S., "Phytochemical investigation of Pimpinella serbica" in Journal of the Serbian Chemical Society, 86, no. 12 (2021):1241-1247,
https://doi.org/10.2298/JSC210816081V . .

TY  - DATA
AU  - Vučković, Ivan
AU  - Stiković, Sonja
AU  - Stešević, Danijela
AU  - Jadranin, Milka
AU  - Trifunović, Snežana S.
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5117
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Supplementary data for the article: Vučković, I.; Stiković, S.; Stešević, D.; Jadranin, M.; Trifunović, S. Phytochemical Investigation of Pimpinella Serbica. Journal of the Serbian Chemical Society 2021, 86 (12), 1241–1247. https://doi.org/10.2298/JSC210816081V.
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5117
ER  - 

@misc{
author = "Vučković, Ivan and Stiković, Sonja and Stešević, Danijela and Jadranin, Milka and Trifunović, Snežana S.",
year = "2021",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Supplementary data for the article: Vučković, I.; Stiković, S.; Stešević, D.; Jadranin, M.; Trifunović, S. Phytochemical Investigation of Pimpinella Serbica. Journal of the Serbian Chemical Society 2021, 86 (12), 1241–1247. https://doi.org/10.2298/JSC210816081V.",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5117"
}

Vučković, I., Stiković, S., Stešević, D., Jadranin, M.,& Trifunović, S. S.. (2021). Supplementary data for the article: Vučković, I.; Stiković, S.; Stešević, D.; Jadranin, M.; Trifunović, S. Phytochemical Investigation of Pimpinella Serbica. Journal of the Serbian Chemical Society 2021, 86 (12), 1241–1247. https://doi.org/10.2298/JSC210816081V.. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society..
https://hdl.handle.net/21.15107/rcub_cherry_5117

Vučković I, Stiković S, Stešević D, Jadranin M, Trifunović SS. Supplementary data for the article: Vučković, I.; Stiković, S.; Stešević, D.; Jadranin, M.; Trifunović, S. Phytochemical Investigation of Pimpinella Serbica. Journal of the Serbian Chemical Society 2021, 86 (12), 1241–1247. https://doi.org/10.2298/JSC210816081V.. in Journal of the Serbian Chemical Society. 2021;.
https://hdl.handle.net/21.15107/rcub_cherry_5117 .

Vučković, Ivan, Stiković, Sonja, Stešević, Danijela, Jadranin, Milka, Trifunović, Snežana S., "Supplementary data for the article: Vučković, I.; Stiković, S.; Stešević, D.; Jadranin, M.; Trifunović, S. Phytochemical Investigation of Pimpinella Serbica. Journal of the Serbian Chemical Society 2021, 86 (12), 1241–1247. https://doi.org/10.2298/JSC210816081V." in Journal of the Serbian Chemical Society (2021),
https://hdl.handle.net/21.15107/rcub_cherry_5117 .

TY  - JOUR
AU  - Ivanović, Ljubica
AU  - Topalović, Ana
AU  - Bogdanović, Višnja
AU  - Đurović, Dijana
AU  - Mugoša, Boban
AU  - Jadranin, Milka
AU  - Tešević, Vele
AU  - Beškoski, Vladimir
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4829
AB  - The purpose of this paper is to determine the polyphenol content, antioxidative potential and antiproliferative activity of Swiss chard from Montenegro, grown under different irrigation and fertilization regimes. Design/methodology/approach: Swiss chard was grown in the open field (Lješkopolje, Montenegro) where it was subjected to different fertilization and irrigation regimes. Chard samples were analyzed for previously identified polyphenols and for antioxidant parameters. Additionally, in order to complete the biological activities, chard extracts were tested for antiproliferative activity against MFC-7 and HT-29 tumor cell lines. Findings: The polyphenols identified in Swiss chard were flavonoids: vitexin-2?-O-xyloside, vitexin-6?-O-acetyl-2?-O-xyloside, vitexin-6?-O-malonyl-2?-O-xyloside and isorhamnetin-3,7-diglucoside. In the antioxidant tests, DPPH (2,2-diphenyl-1-picrylhydrazyl), and ABTS (2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid)), chard extract had values of 7.00 and 8.50 (mean values) µmol Trolox (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid) equ/d.w., respectively. The tested chard extracts inhibited cell proliferation at different concentrations (3.125–50.0 µg/mL) against the MCF-7 cell line, after 24 and 48 h of incubation. The antiproliferative activity, expressed in terms of IC50, was 32.97 and 86.45 µg/mL after 24 h of incubation and 20.76 and 23.33 µg/mL after 48 h of incubation, for treated and untreated chard extracts, respectively. Originality/value: These data suggest Montenegrin Swiss chard grown under different irrigation and fertilization treatments can be considered as a functional food and should be included in an everyday diet. The collected data could help in the growth improvement of chard with functional food properties.
PB  - Emerald Publishing Limited
T2  - British Food Journal
T1  - Antiproliferative activity and antioxidative potential of Swiss chard from Montenegro, grown under different irrigation and fertilization regimes
VL  - 123
IS  - 7
SP  - 2335
EP  - 2348
EP  - Supplementary material: [https://cherry.chem.bg.ac.rs/handle/123456789/4830]
DO  - 10.1108/BFJ-11-2020-1062
ER  - 

@article{
author = "Ivanović, Ljubica and Topalović, Ana and Bogdanović, Višnja and Đurović, Dijana and Mugoša, Boban and Jadranin, Milka and Tešević, Vele and Beškoski, Vladimir",
year = "2021",
abstract = "The purpose of this paper is to determine the polyphenol content, antioxidative potential and antiproliferative activity of Swiss chard from Montenegro, grown under different irrigation and fertilization regimes. Design/methodology/approach: Swiss chard was grown in the open field (Lješkopolje, Montenegro) where it was subjected to different fertilization and irrigation regimes. Chard samples were analyzed for previously identified polyphenols and for antioxidant parameters. Additionally, in order to complete the biological activities, chard extracts were tested for antiproliferative activity against MFC-7 and HT-29 tumor cell lines. Findings: The polyphenols identified in Swiss chard were flavonoids: vitexin-2?-O-xyloside, vitexin-6?-O-acetyl-2?-O-xyloside, vitexin-6?-O-malonyl-2?-O-xyloside and isorhamnetin-3,7-diglucoside. In the antioxidant tests, DPPH (2,2-diphenyl-1-picrylhydrazyl), and ABTS (2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid)), chard extract had values of 7.00 and 8.50 (mean values) µmol Trolox (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid) equ/d.w., respectively. The tested chard extracts inhibited cell proliferation at different concentrations (3.125–50.0 µg/mL) against the MCF-7 cell line, after 24 and 48 h of incubation. The antiproliferative activity, expressed in terms of IC50, was 32.97 and 86.45 µg/mL after 24 h of incubation and 20.76 and 23.33 µg/mL after 48 h of incubation, for treated and untreated chard extracts, respectively. Originality/value: These data suggest Montenegrin Swiss chard grown under different irrigation and fertilization treatments can be considered as a functional food and should be included in an everyday diet. The collected data could help in the growth improvement of chard with functional food properties.",
publisher = "Emerald Publishing Limited",
journal = "British Food Journal",
title = "Antiproliferative activity and antioxidative potential of Swiss chard from Montenegro, grown under different irrigation and fertilization regimes",
volume = "123",
number = "7",
pages = "2335-2348-Supplementary material: [https://cherry.chem.bg.ac.rs/handle/123456789/4830]",
doi = "10.1108/BFJ-11-2020-1062"
}

Ivanović, L., Topalović, A., Bogdanović, V., Đurović, D., Mugoša, B., Jadranin, M., Tešević, V.,& Beškoski, V.. (2021). Antiproliferative activity and antioxidative potential of Swiss chard from Montenegro, grown under different irrigation and fertilization regimes. in British Food Journal
Emerald Publishing Limited., 123(7), 2335-2348.
https://doi.org/10.1108/BFJ-11-2020-1062

Ivanović L, Topalović A, Bogdanović V, Đurović D, Mugoša B, Jadranin M, Tešević V, Beškoski V. Antiproliferative activity and antioxidative potential of Swiss chard from Montenegro, grown under different irrigation and fertilization regimes. in British Food Journal. 2021;123(7):2335-2348.
doi:10.1108/BFJ-11-2020-1062 .

Ivanović, Ljubica, Topalović, Ana, Bogdanović, Višnja, Đurović, Dijana, Mugoša, Boban, Jadranin, Milka, Tešević, Vele, Beškoski, Vladimir, "Antiproliferative activity and antioxidative potential of Swiss chard from Montenegro, grown under different irrigation and fertilization regimes" in British Food Journal, 123, no. 7 (2021):2335-2348,
https://doi.org/10.1108/BFJ-11-2020-1062 . .

TY  - JOUR
AU  - Čukanović, Jelena
AU  - Tešević, Vele
AU  - Jadranin, Milka
AU  - Ljubojević, Mirjana
AU  - Mladenović, Emina
AU  - Kostić, Saša
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3806
AB  - Horse chestnut (Aesculus hippocastanum L.) is a deciduous tree which is widely used on urban green spaces in Serbia. Also, the seed of horse chestnut is an important raw material in pharmaceutical industry, owing to its medicinal properties. In this study, the content of fatty acids, flavonoids, aescin and heavy metals in seeds of 11 horse chestnut genotypes growing in urban conditions was investigated. A total of 16 fatty acids were identified. Unsaturated fatty acids in seed samples were the most abundat. Among the saturated fatty acids, palmitic acid was the dominant one, with a total average content of 8.12%. Oleic acid, with the total average content of 53.46%, was the most abundant unsaturated fatty acid. The results of this study indicated the presence of the following flavonoids: quercetin, kaempferol and rutin. Rutin was the most abundant, averagely contributing with 6.071 μg/g to the total quantified polyphenolics in all samples. The total aescin content ranged from 0.82% to 4.16%. Fruits of park and street trees from small- and middle-sized cities can be used in pharmaceutical industry as raw material. Differences between different urban site categories and localities were detected, which indicates the biochemical plasticity of the seeds to urban morphology.
PB  - Elsevier
T2  - Biochemical Systematics and Ecology
T1  - Horse chestnut (Aesculus hippocastanum L.) seed fatty acids, flavonoids and heavy metals plasticity to different urban environments
VL  - 89
EP  - 103980
DO  - 10.1016/j.bse.2019.103980
ER  - 

@article{
author = "Čukanović, Jelena and Tešević, Vele and Jadranin, Milka and Ljubojević, Mirjana and Mladenović, Emina and Kostić, Saša",
year = "2020",
abstract = "Horse chestnut (Aesculus hippocastanum L.) is a deciduous tree which is widely used on urban green spaces in Serbia. Also, the seed of horse chestnut is an important raw material in pharmaceutical industry, owing to its medicinal properties. In this study, the content of fatty acids, flavonoids, aescin and heavy metals in seeds of 11 horse chestnut genotypes growing in urban conditions was investigated. A total of 16 fatty acids were identified. Unsaturated fatty acids in seed samples were the most abundat. Among the saturated fatty acids, palmitic acid was the dominant one, with a total average content of 8.12%. Oleic acid, with the total average content of 53.46%, was the most abundant unsaturated fatty acid. The results of this study indicated the presence of the following flavonoids: quercetin, kaempferol and rutin. Rutin was the most abundant, averagely contributing with 6.071 μg/g to the total quantified polyphenolics in all samples. The total aescin content ranged from 0.82% to 4.16%. Fruits of park and street trees from small- and middle-sized cities can be used in pharmaceutical industry as raw material. Differences between different urban site categories and localities were detected, which indicates the biochemical plasticity of the seeds to urban morphology.",
publisher = "Elsevier",
journal = "Biochemical Systematics and Ecology",
title = "Horse chestnut (Aesculus hippocastanum L.) seed fatty acids, flavonoids and heavy metals plasticity to different urban environments",
volume = "89",
pages = "103980",
doi = "10.1016/j.bse.2019.103980"
}

Čukanović, J., Tešević, V., Jadranin, M., Ljubojević, M., Mladenović, E.,& Kostić, S.. (2020). Horse chestnut (Aesculus hippocastanum L.) seed fatty acids, flavonoids and heavy metals plasticity to different urban environments. in Biochemical Systematics and Ecology
Elsevier., 89.
https://doi.org/10.1016/j.bse.2019.103980

Čukanović J, Tešević V, Jadranin M, Ljubojević M, Mladenović E, Kostić S. Horse chestnut (Aesculus hippocastanum L.) seed fatty acids, flavonoids and heavy metals plasticity to different urban environments. in Biochemical Systematics and Ecology. 2020;89:null-103980.
doi:10.1016/j.bse.2019.103980 .

Čukanović, Jelena, Tešević, Vele, Jadranin, Milka, Ljubojević, Mirjana, Mladenović, Emina, Kostić, Saša, "Horse chestnut (Aesculus hippocastanum L.) seed fatty acids, flavonoids and heavy metals plasticity to different urban environments" in Biochemical Systematics and Ecology, 89 (2020),
https://doi.org/10.1016/j.bse.2019.103980 . .

TY  - JOUR
AU  - Vujić, Bojan
AU  - Vidaković, Vera
AU  - Jadranin, Milka
AU  - Novaković, Irena T.
AU  - Trifunović, Snežana S.
AU  - Tešević, Vele
AU  - Mandić, Boris
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3962
AB  - Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.
PB  - MDPI
T2  - Plants
T1  - Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts
VL  - 9
IS  - 3
SP  - 337
DO  - 10.3390/plants9030337
ER  - 

@article{
author = "Vujić, Bojan and Vidaković, Vera and Jadranin, Milka and Novaković, Irena T. and Trifunović, Snežana S. and Tešević, Vele and Mandić, Boris",
year = "2020",
abstract = "Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.",
publisher = "MDPI",
journal = "Plants",
title = "Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts",
volume = "9",
number = "3",
pages = "337",
doi = "10.3390/plants9030337"
}

Vujić, B., Vidaković, V., Jadranin, M., Novaković, I. T., Trifunović, S. S., Tešević, V.,& Mandić, B.. (2020). Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts. in Plants
MDPI., 9(3), 337.
https://doi.org/10.3390/plants9030337

Vujić B, Vidaković V, Jadranin M, Novaković IT, Trifunović SS, Tešević V, Mandić B. Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts. in Plants. 2020;9(3):337.
doi:10.3390/plants9030337 .

Vujić, Bojan, Vidaković, Vera, Jadranin, Milka, Novaković, Irena T., Trifunović, Snežana S., Tešević, Vele, Mandić, Boris, "Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts" in Plants, 9, no. 3 (2020):337,
https://doi.org/10.3390/plants9030337 . .

TY  - JOUR
AU  - Lisov, Nikolina
AU  - Petrovic, Aleksandar
AU  - Čakar, Uroš
AU  - Jadranin, Milka
AU  - Tešević, Vele
AU  - Bukarica-Gojković, Ljiljana
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4309
AB  - In this study, we estimated the usage of Cabernet Sauvignon in microvinifications, obtaining wines with increased phenolic compound content. Kinetic extraction of phenolic compounds during alcoholic fermentation was affected by maceration time (3, 5, 7, 14 and 21 days) and the addition and kinetics of enzyme preparations (EP). The highest extraction rates were observed for catechin (EXV EP – EXV enzyme preparation and CP EP – Color plus enzyme preparation) and p-hydroxybenzoic acid (Car EP - Caractere enzyme preparation). According to extraction time of the analyzed phenolic compounds, maximal values (ellagic acid, ferulic acid, chlorogenic acid, caffeic acid, naringenin, p-hydroxybenzoic acid, p-coumaric acid, protocatechuic acid, trans-resveratrol, syringic acid, vanillin, and vanillic acid) were obtained on day 15 of maceration with addition of CP EP, with exceptions of gallic acid, catechin, and myricetin. Prolonged maceration times, up to 21 days, showed the most potent DPPH free radical scavenging activity with Car EP and the highest Ferric Reducing Ability of Plasma (FRAP) values with CP EP.
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Extraction kinetic of some phenolic compounds during Cabernet Sauvignon alcoholic fermentation and antioxidant properties of derived wines
VL  - 39
IS  - 2
SP  - 185
EP  - 196
DO  - 10.20450/mjcce.2020.2060
ER  - 

@article{
author = "Lisov, Nikolina and Petrovic, Aleksandar and Čakar, Uroš and Jadranin, Milka and Tešević, Vele and Bukarica-Gojković, Ljiljana",
year = "2020",
abstract = "In this study, we estimated the usage of Cabernet Sauvignon in microvinifications, obtaining wines with increased phenolic compound content. Kinetic extraction of phenolic compounds during alcoholic fermentation was affected by maceration time (3, 5, 7, 14 and 21 days) and the addition and kinetics of enzyme preparations (EP). The highest extraction rates were observed for catechin (EXV EP – EXV enzyme preparation and CP EP – Color plus enzyme preparation) and p-hydroxybenzoic acid (Car EP - Caractere enzyme preparation). According to extraction time of the analyzed phenolic compounds, maximal values (ellagic acid, ferulic acid, chlorogenic acid, caffeic acid, naringenin, p-hydroxybenzoic acid, p-coumaric acid, protocatechuic acid, trans-resveratrol, syringic acid, vanillin, and vanillic acid) were obtained on day 15 of maceration with addition of CP EP, with exceptions of gallic acid, catechin, and myricetin. Prolonged maceration times, up to 21 days, showed the most potent DPPH free radical scavenging activity with Car EP and the highest Ferric Reducing Ability of Plasma (FRAP) values with CP EP.",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Extraction kinetic of some phenolic compounds during Cabernet Sauvignon alcoholic fermentation and antioxidant properties of derived wines",
volume = "39",
number = "2",
pages = "185-196",
doi = "10.20450/mjcce.2020.2060"
}

Lisov, N., Petrovic, A., Čakar, U., Jadranin, M., Tešević, V.,& Bukarica-Gojković, L.. (2020). Extraction kinetic of some phenolic compounds during Cabernet Sauvignon alcoholic fermentation and antioxidant properties of derived wines. in Macedonian Journal of Chemistry and Chemical Engineering, 39(2), 185-196.
https://doi.org/10.20450/mjcce.2020.2060

Lisov N, Petrovic A, Čakar U, Jadranin M, Tešević V, Bukarica-Gojković L. Extraction kinetic of some phenolic compounds during Cabernet Sauvignon alcoholic fermentation and antioxidant properties of derived wines. in Macedonian Journal of Chemistry and Chemical Engineering. 2020;39(2):185-196.
doi:10.20450/mjcce.2020.2060 .

Lisov, Nikolina, Petrovic, Aleksandar, Čakar, Uroš, Jadranin, Milka, Tešević, Vele, Bukarica-Gojković, Ljiljana, "Extraction kinetic of some phenolic compounds during Cabernet Sauvignon alcoholic fermentation and antioxidant properties of derived wines" in Macedonian Journal of Chemistry and Chemical Engineering, 39, no. 2 (2020):185-196,
https://doi.org/10.20450/mjcce.2020.2060 . .

TY  - DATA
AU  - Čukanović, Jelena
AU  - Tešević, Vele
AU  - Jadranin, Milka
AU  - Ljubojević, Mirjana
AU  - Mladenović, Emina
AU  - Kostić, Saša
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3807
PB  - Elsevier
T2  - Biochemical Systematics and Ecology
T1  - Supplementary data for article: Čukanović, J.; Tešević, V.; Jadranin, M.; Ljubojević, M.; Mladenović, E.; Kostić, S. Horse Chestnut (Aesculus Hippocastanum L.) Seed Fatty Acids, Flavonoids and Heavy Metals Plasticity to Different Urban Environments. Biochemical Systematics and Ecology 2020, 89. https://doi.org/10.1016/j.bse.2019.103980
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3807
ER  - 

@misc{
author = "Čukanović, Jelena and Tešević, Vele and Jadranin, Milka and Ljubojević, Mirjana and Mladenović, Emina and Kostić, Saša",
year = "2020",
publisher = "Elsevier",
journal = "Biochemical Systematics and Ecology",
title = "Supplementary data for article: Čukanović, J.; Tešević, V.; Jadranin, M.; Ljubojević, M.; Mladenović, E.; Kostić, S. Horse Chestnut (Aesculus Hippocastanum L.) Seed Fatty Acids, Flavonoids and Heavy Metals Plasticity to Different Urban Environments. Biochemical Systematics and Ecology 2020, 89. https://doi.org/10.1016/j.bse.2019.103980",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3807"
}

Čukanović, J., Tešević, V., Jadranin, M., Ljubojević, M., Mladenović, E.,& Kostić, S.. (2020). Supplementary data for article: Čukanović, J.; Tešević, V.; Jadranin, M.; Ljubojević, M.; Mladenović, E.; Kostić, S. Horse Chestnut (Aesculus Hippocastanum L.) Seed Fatty Acids, Flavonoids and Heavy Metals Plasticity to Different Urban Environments. Biochemical Systematics and Ecology 2020, 89. https://doi.org/10.1016/j.bse.2019.103980. in Biochemical Systematics and Ecology
Elsevier..
https://hdl.handle.net/21.15107/rcub_cherry_3807

Čukanović J, Tešević V, Jadranin M, Ljubojević M, Mladenović E, Kostić S. Supplementary data for article: Čukanović, J.; Tešević, V.; Jadranin, M.; Ljubojević, M.; Mladenović, E.; Kostić, S. Horse Chestnut (Aesculus Hippocastanum L.) Seed Fatty Acids, Flavonoids and Heavy Metals Plasticity to Different Urban Environments. Biochemical Systematics and Ecology 2020, 89. https://doi.org/10.1016/j.bse.2019.103980. in Biochemical Systematics and Ecology. 2020;.
https://hdl.handle.net/21.15107/rcub_cherry_3807 .

Čukanović, Jelena, Tešević, Vele, Jadranin, Milka, Ljubojević, Mirjana, Mladenović, Emina, Kostić, Saša, "Supplementary data for article: Čukanović, J.; Tešević, V.; Jadranin, M.; Ljubojević, M.; Mladenović, E.; Kostić, S. Horse Chestnut (Aesculus Hippocastanum L.) Seed Fatty Acids, Flavonoids and Heavy Metals Plasticity to Different Urban Environments. Biochemical Systematics and Ecology 2020, 89. https://doi.org/10.1016/j.bse.2019.103980" in Biochemical Systematics and Ecology (2020),
https://hdl.handle.net/21.15107/rcub_cherry_3807 .

TY  - JOUR
AU  - Krstić, Gordana B.
AU  - Jadranin, Milka
AU  - Stanković, Miroslava
AU  - Aljančić, Ivana
AU  - Vujisić, Ljubodrag V.
AU  - Mandić, Boris
AU  - Tešević, Vele
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3143
AB  - Two sets of structurally different jatrophanes (1-11 and 13-16), jatrophane 12, and latex extract of 2 Euphorbia species (17 and 18) were tested for in vitro protective effect against chromosome aberrations in peripheral human lymphocytes using the cytokinesis-block micronucleus (CBMN) assay. Jatrophanes 1-6 in minimal doses of 1 µg/mL prominently decreased micronuclei (MN) frequency in the range 44.86% to 34.29% and manifested considerable protective effect. From the other set of jatrophanes, 13 in the same minimal dose notably decreased MN frequency by 31.05%, while extracts 17 and 18 at a concentration of 4 µg/mL remarkably decreased the frequency of MN by 37.94% and 36.12%, respectively. Jatrophanes 12, 14, and 16 showed moderate protection, while 7-11 and 15 were less active than positive control. The structure-activity relationship (SAR) studies of the tested jatrophanes (1-16) indicated the favorable position of benzoate at C-8 or C-9 (3, 4, and 13) and a preference of isobutanoyloxy group at C-3 (1-3) rather than propanoyloxy at the same position (4-6) for pronounced protective effect on human lymphocytes DNA. In a previous SAR study on 11 jatrophanes (1, 3-8, and 13-16), the same structural features in 3, 4, and 13 influenced powerful inhibition of P-gp, while growth inhibition of cancer cells was more than doubled in 1 (isobutanoyloxy group at C-3) compared to 6 (propanoyloxy at C-3).
PB  - SAGE Journals
T2  - Natural Product Communications
T1  - Jatrophane Diterpenoids With Protective Effect on Human Lymphocytes DNA
VL  - 14
IS  - 5
DO  - 10.1177/1934578X19848168
ER  - 

@article{
author = "Krstić, Gordana B. and Jadranin, Milka and Stanković, Miroslava and Aljančić, Ivana and Vujisić, Ljubodrag V. and Mandić, Boris and Tešević, Vele",
year = "2019",
abstract = "Two sets of structurally different jatrophanes (1-11 and 13-16), jatrophane 12, and latex extract of 2 Euphorbia species (17 and 18) were tested for in vitro protective effect against chromosome aberrations in peripheral human lymphocytes using the cytokinesis-block micronucleus (CBMN) assay. Jatrophanes 1-6 in minimal doses of 1 µg/mL prominently decreased micronuclei (MN) frequency in the range 44.86% to 34.29% and manifested considerable protective effect. From the other set of jatrophanes, 13 in the same minimal dose notably decreased MN frequency by 31.05%, while extracts 17 and 18 at a concentration of 4 µg/mL remarkably decreased the frequency of MN by 37.94% and 36.12%, respectively. Jatrophanes 12, 14, and 16 showed moderate protection, while 7-11 and 15 were less active than positive control. The structure-activity relationship (SAR) studies of the tested jatrophanes (1-16) indicated the favorable position of benzoate at C-8 or C-9 (3, 4, and 13) and a preference of isobutanoyloxy group at C-3 (1-3) rather than propanoyloxy at the same position (4-6) for pronounced protective effect on human lymphocytes DNA. In a previous SAR study on 11 jatrophanes (1, 3-8, and 13-16), the same structural features in 3, 4, and 13 influenced powerful inhibition of P-gp, while growth inhibition of cancer cells was more than doubled in 1 (isobutanoyloxy group at C-3) compared to 6 (propanoyloxy at C-3).",
publisher = "SAGE Journals",
journal = "Natural Product Communications",
title = "Jatrophane Diterpenoids With Protective Effect on Human Lymphocytes DNA",
volume = "14",
number = "5",
doi = "10.1177/1934578X19848168"
}

Krstić, G. B., Jadranin, M., Stanković, M., Aljančić, I., Vujisić, L. V., Mandić, B.,& Tešević, V.. (2019). Jatrophane Diterpenoids With Protective Effect on Human Lymphocytes DNA. in Natural Product Communications
SAGE Journals., 14(5).
https://doi.org/10.1177/1934578X19848168

Krstić GB, Jadranin M, Stanković M, Aljančić I, Vujisić LV, Mandić B, Tešević V. Jatrophane Diterpenoids With Protective Effect on Human Lymphocytes DNA. in Natural Product Communications. 2019;14(5).
doi:10.1177/1934578X19848168 .

Krstić, Gordana B., Jadranin, Milka, Stanković, Miroslava, Aljančić, Ivana, Vujisić, Ljubodrag V., Mandić, Boris, Tešević, Vele, "Jatrophane Diterpenoids With Protective Effect on Human Lymphocytes DNA" in Natural Product Communications, 14, no. 5 (2019),
https://doi.org/10.1177/1934578X19848168 . .

TY  - JOUR
AU  - Krstić, Gordana B.
AU  - Novaković, Miroslav M.
AU  - Jadranin, Milka
AU  - Tešević, Vele
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3931
AB  - In this study, three tetracyclic triterpenes: (3S,24S)-tirucall-7-ene-3,24,25-triol (1), (3S,24R)-tirucall-7-ene-3,24,25-triol (2) and inoterpene C (3), were isolated from the milkweed Euphorbia nicaeensis All. using dry-column flash silica gel chromatography and semipreparative normal-phase HPLC. Their structures were determined on the basis of 1D and 2D NMR spectra and literature review. Although these three compounds have previously been isolated from other plant species, this is the first time that they have been isolated from E. nicaeensis.
T2  - Advanced Technologies
T1  - Tetracyclic triterpenoids from Euphorbia nicaeensis All
VL  - 8
IS  - 2
SP  - 37
EP  - 45
DO  - 10.5937/savteh1902037K
ER  - 

@article{
author = "Krstić, Gordana B. and Novaković, Miroslav M. and Jadranin, Milka and Tešević, Vele",
year = "2019",
abstract = "In this study, three tetracyclic triterpenes: (3S,24S)-tirucall-7-ene-3,24,25-triol (1), (3S,24R)-tirucall-7-ene-3,24,25-triol (2) and inoterpene C (3), were isolated from the milkweed Euphorbia nicaeensis All. using dry-column flash silica gel chromatography and semipreparative normal-phase HPLC. Their structures were determined on the basis of 1D and 2D NMR spectra and literature review. Although these three compounds have previously been isolated from other plant species, this is the first time that they have been isolated from E. nicaeensis.",
journal = "Advanced Technologies",
title = "Tetracyclic triterpenoids from Euphorbia nicaeensis All",
volume = "8",
number = "2",
pages = "37-45",
doi = "10.5937/savteh1902037K"
}

Krstić, G. B., Novaković, M. M., Jadranin, M.,& Tešević, V.. (2019). Tetracyclic triterpenoids from Euphorbia nicaeensis All. in Advanced Technologies, 8(2), 37-45.
https://doi.org/10.5937/savteh1902037K

Krstić GB, Novaković MM, Jadranin M, Tešević V. Tetracyclic triterpenoids from Euphorbia nicaeensis All. in Advanced Technologies. 2019;8(2):37-45.
doi:10.5937/savteh1902037K .

Krstić, Gordana B., Novaković, Miroslav M., Jadranin, Milka, Tešević, Vele, "Tetracyclic triterpenoids from Euphorbia nicaeensis All" in Advanced Technologies, 8, no. 2 (2019):37-45,
https://doi.org/10.5937/savteh1902037K . .

TY  - JOUR
AU  - Cvetković, Mirjana
AU  - Đorđević, Iris
AU  - Jadranin, Milka
AU  - Stanković, Miroslava
AU  - Mandić, Boris
AU  - Milosavljević, Slobodan M.
AU  - Vujisić, Ljubodrag V.
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4938
AB  - Analysis of composition of CH2Cl2 surface extract of leaves of Amphoricarpos neumayeri Vis. revealed 16 sesquiterpene lactones with guaianolide skeleton, so called amphoricarpolides, typical for this genus. Four of them, 13–16, were new derivatives and their structures were elucidated by detailed analyses of IR, NMR and MS data. Amphoricarpolide (9), its 15-O-acetyl derivative (5), and two 9β-hydroxyamphoricarpolides, 3,15-di-O-acetyl- and 3-O-acetyl-15-O-isovaleroyl derivatives (3 and 6, respectively) were tested for in vitro protective effect on chromosome aberrations in peripheral human lymphocytes using cytochalasin-B blocked micronucleus (CBMN) assay. The tested compound exerted a beneficial effect by decreasing DNA damage of human lymphocytes.
PB  - Informa UK Limited
T2  - Natural Product Research
T1  - Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA
SP  - 1
EP  - 9
DO  - 10.1080/14786419.2019.1687470
ER  - 

@article{
author = "Cvetković, Mirjana and Đorđević, Iris and Jadranin, Milka and Stanković, Miroslava and Mandić, Boris and Milosavljević, Slobodan M. and Vujisić, Ljubodrag V.",
year = "2019",
abstract = "Analysis of composition of CH2Cl2 surface extract of leaves of Amphoricarpos neumayeri Vis. revealed 16 sesquiterpene lactones with guaianolide skeleton, so called amphoricarpolides, typical for this genus. Four of them, 13–16, were new derivatives and their structures were elucidated by detailed analyses of IR, NMR and MS data. Amphoricarpolide (9), its 15-O-acetyl derivative (5), and two 9β-hydroxyamphoricarpolides, 3,15-di-O-acetyl- and 3-O-acetyl-15-O-isovaleroyl derivatives (3 and 6, respectively) were tested for in vitro protective effect on chromosome aberrations in peripheral human lymphocytes using cytochalasin-B blocked micronucleus (CBMN) assay. The tested compound exerted a beneficial effect by decreasing DNA damage of human lymphocytes.",
publisher = "Informa UK Limited",
journal = "Natural Product Research",
title = "Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA",
pages = "1-9",
doi = "10.1080/14786419.2019.1687470"
}

Cvetković, M., Đorđević, I., Jadranin, M., Stanković, M., Mandić, B., Milosavljević, S. M.,& Vujisić, L. V.. (2019). Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA. in Natural Product Research
Informa UK Limited., 1-9.
https://doi.org/10.1080/14786419.2019.1687470

Cvetković M, Đorđević I, Jadranin M, Stanković M, Mandić B, Milosavljević SM, Vujisić LV. Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA. in Natural Product Research. 2019;:1-9.
doi:10.1080/14786419.2019.1687470 .

Cvetković, Mirjana, Đorđević, Iris, Jadranin, Milka, Stanković, Miroslava, Mandić, Boris, Milosavljević, Slobodan M., Vujisić, Ljubodrag V., "Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA" in Natural Product Research (2019):1-9,
https://doi.org/10.1080/14786419.2019.1687470 . .

TY  - JOUR
AU  - Trifunović-Macedoljan, Jelena
AU  - Pantelić, Nebojša Đ.
AU  - Jadranin, Milka
AU  - Juranić, Ivan O.
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3724
AB  - The biosynthetic pathway of biogenic amines is very active during the growth of many tumour cells. Non-Hodgkin lymphoma represents a very heterogeneous group of malignancies. The concentration level of some biogenic amines (putrescine, histamine, spermidine, epinephrine, and spermine) was investigated to elucidate whether they could be observed as markers for the patients with non-Hodgkin’s lymphoma. In this study, the method of acidic extraction of five biogenic amines from human serum, dansyl chloride pre-column derivatization, and LC/DAD analysis were used to determine the content of biogenic amines in biological fluids. The results indicate that statistically significant differences exist in putrescine, spermidine and histamine contents in non-Hodgkin’s patients versus healthy controls. The concentrations of putrescine, spermidine and epinephrine were elevated, and histamine was lower compared to controls. Based on their content, serum biogenic amines could be considered as potential tumour markers.
PB  - Editura Academiei Romane
T2  - Revue Roumaine de Chimie
T1  - Biogenic amines content in the serum of patients with non-Hodgkin’s lymphoma
VL  - 64
IS  - 8
SP  - 681
EP  - 686
DO  - 10.3224/rrch.2019.64.8.05
ER  - 

@article{
author = "Trifunović-Macedoljan, Jelena and Pantelić, Nebojša Đ. and Jadranin, Milka and Juranić, Ivan O.",
year = "2019",
abstract = "The biosynthetic pathway of biogenic amines is very active during the growth of many tumour cells. Non-Hodgkin lymphoma represents a very heterogeneous group of malignancies. The concentration level of some biogenic amines (putrescine, histamine, spermidine, epinephrine, and spermine) was investigated to elucidate whether they could be observed as markers for the patients with non-Hodgkin’s lymphoma. In this study, the method of acidic extraction of five biogenic amines from human serum, dansyl chloride pre-column derivatization, and LC/DAD analysis were used to determine the content of biogenic amines in biological fluids. The results indicate that statistically significant differences exist in putrescine, spermidine and histamine contents in non-Hodgkin’s patients versus healthy controls. The concentrations of putrescine, spermidine and epinephrine were elevated, and histamine was lower compared to controls. Based on their content, serum biogenic amines could be considered as potential tumour markers.",
publisher = "Editura Academiei Romane",
journal = "Revue Roumaine de Chimie",
title = "Biogenic amines content in the serum of patients with non-Hodgkin’s lymphoma",
volume = "64",
number = "8",
pages = "681-686",
doi = "10.3224/rrch.2019.64.8.05"
}

Trifunović-Macedoljan, J., Pantelić, N. Đ., Jadranin, M.,& Juranić, I. O.. (2019). Biogenic amines content in the serum of patients with non-Hodgkin’s lymphoma. in Revue Roumaine de Chimie
Editura Academiei Romane., 64(8), 681-686.
https://doi.org/10.3224/rrch.2019.64.8.05

Trifunović-Macedoljan J, Pantelić NĐ, Jadranin M, Juranić IO. Biogenic amines content in the serum of patients with non-Hodgkin’s lymphoma. in Revue Roumaine de Chimie. 2019;64(8):681-686.
doi:10.3224/rrch.2019.64.8.05 .

Trifunović-Macedoljan, Jelena, Pantelić, Nebojša Đ., Jadranin, Milka, Juranić, Ivan O., "Biogenic amines content in the serum of patients with non-Hodgkin’s lymphoma" in Revue Roumaine de Chimie, 64, no. 8 (2019):681-686,
https://doi.org/10.3224/rrch.2019.64.8.05 . .

TY  - JOUR
AU  - Ljekočević, Marko
AU  - Jadranin, Milka
AU  - Stanković, Jovana
AU  - Popović, Branko
AU  - Nikićević, Ninoslav
AU  - Petrović, Aleksandar
AU  - Tešević, Vele
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3047
AB  - Plum wines made from two cultivars of Prunus domestica L. (Požegača and Crvena ranka) and one cultivar of Prunus insititia L. (Trnovača) were evaluated for their total phenolic and anthocyanin contents. LC–MS/MS analysis based on specific MS transitions in the multiple reaction monitoring (MRM) mode was used for the identification and quantification of selected phenolic compounds. Catechin, chlorogenic and caffeic acids, as well as quercetin, were identified as the main polyphenols in plum wines. The total amount of phenolic compounds ranged from 1.24 to 1.58 g gallic acid equivalent per L. Among the examined wines, the Crvena ranka wine had a higher content of anthocyanins (12.31 mg cyanidin-3-glucoside equivalent per L). The antioxidant capacity of the wines was determined using the DPPH assay. The variations in the physicochemical characteristics, phenolic composition and DPPH radical scavenging activity of these wines are related to differences due to the different plum cultivars used in the preparation of each wine
T2  - Journal of the Serbian Chemical Society
T1  - Phenolic composition and DPPH radical scavenging activity of plum wine produced from three plum cultivars
VL  - 84
IS  - 2
SP  - 141
EP  - 151
DO  - 10.2298/JSC180710096L
ER  - 

@article{
author = "Ljekočević, Marko and Jadranin, Milka and Stanković, Jovana and Popović, Branko and Nikićević, Ninoslav and Petrović, Aleksandar and Tešević, Vele",
year = "2019",
abstract = "Plum wines made from two cultivars of Prunus domestica L. (Požegača and Crvena ranka) and one cultivar of Prunus insititia L. (Trnovača) were evaluated for their total phenolic and anthocyanin contents. LC–MS/MS analysis based on specific MS transitions in the multiple reaction monitoring (MRM) mode was used for the identification and quantification of selected phenolic compounds. Catechin, chlorogenic and caffeic acids, as well as quercetin, were identified as the main polyphenols in plum wines. The total amount of phenolic compounds ranged from 1.24 to 1.58 g gallic acid equivalent per L. Among the examined wines, the Crvena ranka wine had a higher content of anthocyanins (12.31 mg cyanidin-3-glucoside equivalent per L). The antioxidant capacity of the wines was determined using the DPPH assay. The variations in the physicochemical characteristics, phenolic composition and DPPH radical scavenging activity of these wines are related to differences due to the different plum cultivars used in the preparation of each wine",
journal = "Journal of the Serbian Chemical Society",
title = "Phenolic composition and DPPH radical scavenging activity of plum wine produced from three plum cultivars",
volume = "84",
number = "2",
pages = "141-151",
doi = "10.2298/JSC180710096L"
}

Ljekočević, M., Jadranin, M., Stanković, J., Popović, B., Nikićević, N., Petrović, A.,& Tešević, V.. (2019). Phenolic composition and DPPH radical scavenging activity of plum wine produced from three plum cultivars. in Journal of the Serbian Chemical Society, 84(2), 141-151.
https://doi.org/10.2298/JSC180710096L

Ljekočević M, Jadranin M, Stanković J, Popović B, Nikićević N, Petrović A, Tešević V. Phenolic composition and DPPH radical scavenging activity of plum wine produced from three plum cultivars. in Journal of the Serbian Chemical Society. 2019;84(2):141-151.
doi:10.2298/JSC180710096L .

Ljekočević, Marko, Jadranin, Milka, Stanković, Jovana, Popović, Branko, Nikićević, Ninoslav, Petrović, Aleksandar, Tešević, Vele, "Phenolic composition and DPPH radical scavenging activity of plum wine produced from three plum cultivars" in Journal of the Serbian Chemical Society, 84, no. 2 (2019):141-151,
https://doi.org/10.2298/JSC180710096L . .

TY  - DATA
AU  - Cvetković, Mirjana
AU  - Anđelković, Boban D.
AU  - Stevanović, Vladimir
AU  - Jadranin, Milka
AU  - Đorđević, Iris
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan M.
AU  - Gođevac, Dejan
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3242
PB  - Elsevier Science Bv, Amsterdam
T2  - Phytochemistry Letters
T1  - Supplementary material for the article: Cvetković, M.; Anđelković, B.; Stevanović, V.; Jadranin, M.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. NMR-Based Metabolomics Study of Amphoricarpos Species from Montenegro. Phytochemistry Letters 2018, 25, 1–5. https://doi.org/10.1016/j.phytol.2018.03.013
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3242
ER  - 

@misc{
author = "Cvetković, Mirjana and Anđelković, Boban D. and Stevanović, Vladimir and Jadranin, Milka and Đorđević, Iris and Tešević, Vele and Milosavljević, Slobodan M. and Gođevac, Dejan",
year = "2018",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Phytochemistry Letters",
title = "Supplementary material for the article: Cvetković, M.; Anđelković, B.; Stevanović, V.; Jadranin, M.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. NMR-Based Metabolomics Study of Amphoricarpos Species from Montenegro. Phytochemistry Letters 2018, 25, 1–5. https://doi.org/10.1016/j.phytol.2018.03.013",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3242"
}

Cvetković, M., Anđelković, B. D., Stevanović, V., Jadranin, M., Đorđević, I., Tešević, V., Milosavljević, S. M.,& Gođevac, D.. (2018). Supplementary material for the article: Cvetković, M.; Anđelković, B.; Stevanović, V.; Jadranin, M.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. NMR-Based Metabolomics Study of Amphoricarpos Species from Montenegro. Phytochemistry Letters 2018, 25, 1–5. https://doi.org/10.1016/j.phytol.2018.03.013. in Phytochemistry Letters
Elsevier Science Bv, Amsterdam..
https://hdl.handle.net/21.15107/rcub_cherry_3242

Cvetković M, Anđelković BD, Stevanović V, Jadranin M, Đorđević I, Tešević V, Milosavljević SM, Gođevac D. Supplementary material for the article: Cvetković, M.; Anđelković, B.; Stevanović, V.; Jadranin, M.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. NMR-Based Metabolomics Study of Amphoricarpos Species from Montenegro. Phytochemistry Letters 2018, 25, 1–5. https://doi.org/10.1016/j.phytol.2018.03.013. in Phytochemistry Letters. 2018;.
https://hdl.handle.net/21.15107/rcub_cherry_3242 .

Cvetković, Mirjana, Anđelković, Boban D., Stevanović, Vladimir, Jadranin, Milka, Đorđević, Iris, Tešević, Vele, Milosavljević, Slobodan M., Gođevac, Dejan, "Supplementary material for the article: Cvetković, M.; Anđelković, B.; Stevanović, V.; Jadranin, M.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. NMR-Based Metabolomics Study of Amphoricarpos Species from Montenegro. Phytochemistry Letters 2018, 25, 1–5. https://doi.org/10.1016/j.phytol.2018.03.013" in Phytochemistry Letters (2018),
https://hdl.handle.net/21.15107/rcub_cherry_3242 .

TY  - JOUR
AU  - Krstić, Gordana B.
AU  - Jadranin, Milka
AU  - Todorović, Nina
AU  - Pešić, Milica
AU  - Stanković, Tijana
AU  - Aljančić, Ivana
AU  - Tešević, Vele
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2108
AB  - Seven previously undescribed jatrophane diterpenoids, nicaeenin A-G, with eight known jatrophane diterpenoids, namely euphodendrophanes A-C, F, N, O, Q S, were isolated from latex of Euphorbia nicaeensis collected in Serbia. The chemical structures of the compounds were determined by spectro-scopic analysis including 1D and 2D NMR and HRESIMS experiments. All but one of the previously undescribed jatrophanes, showed significant potential to inhibit P-glycoprotein (P-gp) activity in two MDR cancer cells (NCI-H460/12 and DLD1-TxR). The most powerful were nicaeenin F and nicaeenin G. Moreover nicaeenin G significantly stronger sensitized NCI-H460/R cells to DOX than Dex-VER. (C) 2018 Elsevier Ltd. All rights reserved.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Phytochemistry
T1  - Jatrophane diterpenoids with multidrug-resistance modulating activity from the latex of Euphorbia nicaeensis
VL  - 148
SP  - 104
EP  - 112
DO  - 10.1016/j.phytochem.2018.01.016
ER  - 

@article{
author = "Krstić, Gordana B. and Jadranin, Milka and Todorović, Nina and Pešić, Milica and Stanković, Tijana and Aljančić, Ivana and Tešević, Vele",
year = "2018",
abstract = "Seven previously undescribed jatrophane diterpenoids, nicaeenin A-G, with eight known jatrophane diterpenoids, namely euphodendrophanes A-C, F, N, O, Q S, were isolated from latex of Euphorbia nicaeensis collected in Serbia. The chemical structures of the compounds were determined by spectro-scopic analysis including 1D and 2D NMR and HRESIMS experiments. All but one of the previously undescribed jatrophanes, showed significant potential to inhibit P-glycoprotein (P-gp) activity in two MDR cancer cells (NCI-H460/12 and DLD1-TxR). The most powerful were nicaeenin F and nicaeenin G. Moreover nicaeenin G significantly stronger sensitized NCI-H460/R cells to DOX than Dex-VER. (C) 2018 Elsevier Ltd. All rights reserved.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Phytochemistry",
title = "Jatrophane diterpenoids with multidrug-resistance modulating activity from the latex of Euphorbia nicaeensis",
volume = "148",
pages = "104-112",
doi = "10.1016/j.phytochem.2018.01.016"
}

Krstić, G. B., Jadranin, M., Todorović, N., Pešić, M., Stanković, T., Aljančić, I.,& Tešević, V.. (2018). Jatrophane diterpenoids with multidrug-resistance modulating activity from the latex of Euphorbia nicaeensis. in Phytochemistry
Pergamon-Elsevier Science Ltd, Oxford., 148, 104-112.
https://doi.org/10.1016/j.phytochem.2018.01.016

Krstić GB, Jadranin M, Todorović N, Pešić M, Stanković T, Aljančić I, Tešević V. Jatrophane diterpenoids with multidrug-resistance modulating activity from the latex of Euphorbia nicaeensis. in Phytochemistry. 2018;148:104-112.
doi:10.1016/j.phytochem.2018.01.016 .

Krstić, Gordana B., Jadranin, Milka, Todorović, Nina, Pešić, Milica, Stanković, Tijana, Aljančić, Ivana, Tešević, Vele, "Jatrophane diterpenoids with multidrug-resistance modulating activity from the latex of Euphorbia nicaeensis" in Phytochemistry, 148 (2018):104-112,
https://doi.org/10.1016/j.phytochem.2018.01.016 . .

TY  - DATA
AU  - Krstić, Gordana B.
AU  - Jadranin, Milka
AU  - Todorović, Nina
AU  - Pešić, Milica
AU  - Stanković, Tijana
AU  - Aljančić, Ivana
AU  - Tešević, Vele
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3234
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Phytochemistry
T1  - Supplementary material for the article: Krstić, G.; Jadranin, M.; Todorović, N. M.; Pešić, M.; Stanković, T.; Aljančić, I. S.; Tešević, V. V. Jatrophane Diterpenoids with Multidrug-Resistance Modulating Activity from the Latex of Euphorbia Nicaeensis. Phytochemistry 2018, 148, 104–112. https://doi.org/10.1016/j.phytochem.2018.01.016
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3234
ER  - 

@misc{
author = "Krstić, Gordana B. and Jadranin, Milka and Todorović, Nina and Pešić, Milica and Stanković, Tijana and Aljančić, Ivana and Tešević, Vele",
year = "2018",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Phytochemistry",
title = "Supplementary material for the article: Krstić, G.; Jadranin, M.; Todorović, N. M.; Pešić, M.; Stanković, T.; Aljančić, I. S.; Tešević, V. V. Jatrophane Diterpenoids with Multidrug-Resistance Modulating Activity from the Latex of Euphorbia Nicaeensis. Phytochemistry 2018, 148, 104–112. https://doi.org/10.1016/j.phytochem.2018.01.016",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3234"
}

Krstić, G. B., Jadranin, M., Todorović, N., Pešić, M., Stanković, T., Aljančić, I.,& Tešević, V.. (2018). Supplementary material for the article: Krstić, G.; Jadranin, M.; Todorović, N. M.; Pešić, M.; Stanković, T.; Aljančić, I. S.; Tešević, V. V. Jatrophane Diterpenoids with Multidrug-Resistance Modulating Activity from the Latex of Euphorbia Nicaeensis. Phytochemistry 2018, 148, 104–112. https://doi.org/10.1016/j.phytochem.2018.01.016. in Phytochemistry
Pergamon-Elsevier Science Ltd, Oxford..
https://hdl.handle.net/21.15107/rcub_cherry_3234

Krstić GB, Jadranin M, Todorović N, Pešić M, Stanković T, Aljančić I, Tešević V. Supplementary material for the article: Krstić, G.; Jadranin, M.; Todorović, N. M.; Pešić, M.; Stanković, T.; Aljančić, I. S.; Tešević, V. V. Jatrophane Diterpenoids with Multidrug-Resistance Modulating Activity from the Latex of Euphorbia Nicaeensis. Phytochemistry 2018, 148, 104–112. https://doi.org/10.1016/j.phytochem.2018.01.016. in Phytochemistry. 2018;.
https://hdl.handle.net/21.15107/rcub_cherry_3234 .

Krstić, Gordana B., Jadranin, Milka, Todorović, Nina, Pešić, Milica, Stanković, Tijana, Aljančić, Ivana, Tešević, Vele, "Supplementary material for the article: Krstić, G.; Jadranin, M.; Todorović, N. M.; Pešić, M.; Stanković, T.; Aljančić, I. S.; Tešević, V. V. Jatrophane Diterpenoids with Multidrug-Resistance Modulating Activity from the Latex of Euphorbia Nicaeensis. Phytochemistry 2018, 148, 104–112. https://doi.org/10.1016/j.phytochem.2018.01.016" in Phytochemistry (2018),
https://hdl.handle.net/21.15107/rcub_cherry_3234 .

TY  - JOUR
AU  - Cvetković, Mirjana
AU  - Anđelković, Boban D.
AU  - Stevanović, Vladimir
AU  - Jadranin, Milka
AU  - Đorđević, Iris
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan M.
AU  - Gođevac, Dejan
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2148
AB  - The genus Amphoricarpos Vis. is endemic of westpart of Balkan peninsula. In order to get more insight into the ambiguous taxonomy of the genus, the metabolomic study of the Amphoricarpos samples, has been undertaken. The(1)H NMR spectroscopy combined with multivariate data analysis has been applied. OPLS-DA has been shown to be the best method for clear discrimination of these samples based on the metabolites present in the extracts. The main difference between A. autariatus and A. neumayeri has been found to be the presence of characteristic sesquiterpene lactones of guaianolide type named amphoricarpolides. While the main sesquiterpene lactone in A. neumayeri was oxidized in position 2, those present in both subspecies of A. autariatus samples were oxidized in position 9. The use of sesquiterpene lactones as taxonomic characters for differentiating species of the Asteraceae family was reviewed elsewhere. For the differentiation of two subspecies, A. autariatus ssp. autariatus, and A. autariatus ssp. bertisceus, chlorogenic and malic acid have been found to be decisive, but these compounds do not have chemotaxonomic significance. Our results were in accordance with above mentioned classification of Blecic and Mayer but they differentiate from those of the recent genomic study of the genus indicating a single, genetically, morphologically and ecologically variable species, without intraspecific taxa.
PB  - Elsevier Science Bv, Amsterdam
T2  - Phytochemistry Letters
T1  - NMR-based metabolomics study of Amphoricarpos species from Montenegro
VL  - 25
SP  - 1
EP  - 5
DO  - 10.1016/j.phytol.2018.03.013
ER  - 

@article{
author = "Cvetković, Mirjana and Anđelković, Boban D. and Stevanović, Vladimir and Jadranin, Milka and Đorđević, Iris and Tešević, Vele and Milosavljević, Slobodan M. and Gođevac, Dejan",
year = "2018",
abstract = "The genus Amphoricarpos Vis. is endemic of westpart of Balkan peninsula. In order to get more insight into the ambiguous taxonomy of the genus, the metabolomic study of the Amphoricarpos samples, has been undertaken. The(1)H NMR spectroscopy combined with multivariate data analysis has been applied. OPLS-DA has been shown to be the best method for clear discrimination of these samples based on the metabolites present in the extracts. The main difference between A. autariatus and A. neumayeri has been found to be the presence of characteristic sesquiterpene lactones of guaianolide type named amphoricarpolides. While the main sesquiterpene lactone in A. neumayeri was oxidized in position 2, those present in both subspecies of A. autariatus samples were oxidized in position 9. The use of sesquiterpene lactones as taxonomic characters for differentiating species of the Asteraceae family was reviewed elsewhere. For the differentiation of two subspecies, A. autariatus ssp. autariatus, and A. autariatus ssp. bertisceus, chlorogenic and malic acid have been found to be decisive, but these compounds do not have chemotaxonomic significance. Our results were in accordance with above mentioned classification of Blecic and Mayer but they differentiate from those of the recent genomic study of the genus indicating a single, genetically, morphologically and ecologically variable species, without intraspecific taxa.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Phytochemistry Letters",
title = "NMR-based metabolomics study of Amphoricarpos species from Montenegro",
volume = "25",
pages = "1-5",
doi = "10.1016/j.phytol.2018.03.013"
}

Cvetković, M., Anđelković, B. D., Stevanović, V., Jadranin, M., Đorđević, I., Tešević, V., Milosavljević, S. M.,& Gođevac, D.. (2018). NMR-based metabolomics study of Amphoricarpos species from Montenegro. in Phytochemistry Letters
Elsevier Science Bv, Amsterdam., 25, 1-5.
https://doi.org/10.1016/j.phytol.2018.03.013

Cvetković M, Anđelković BD, Stevanović V, Jadranin M, Đorđević I, Tešević V, Milosavljević SM, Gođevac D. NMR-based metabolomics study of Amphoricarpos species from Montenegro. in Phytochemistry Letters. 2018;25:1-5.
doi:10.1016/j.phytol.2018.03.013 .

Cvetković, Mirjana, Anđelković, Boban D., Stevanović, Vladimir, Jadranin, Milka, Đorđević, Iris, Tešević, Vele, Milosavljević, Slobodan M., Gođevac, Dejan, "NMR-based metabolomics study of Amphoricarpos species from Montenegro" in Phytochemistry Letters, 25 (2018):1-5,
https://doi.org/10.1016/j.phytol.2018.03.013 . .

TY  - JOUR
AU  - Ljubijankić, Nevzeta
AU  - Stanković, Miomir
AU  - Tešević, Vele
AU  - Grgurić-Šipka, Sanja
AU  - Jadranin, Milka
AU  - Begić, Sabina
AU  - Šabanović, Elma
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/332
AB  - This study evaluates the genotoxic potential of two Ru(III) complexes with thiosemicarbazone based ligands. The complexes were tested for in vitro protective effect on chromosome aberrations in peripheral human lymphocytes using the cytokinesis block micronucleus (CBMN) assay at concentrations 1.5; 3.7 and 7.4 μg/mL. The cell culture treated with the tested complexes, at 3.7 μg/mL concentration, decreased a frequency of micronucleus for 37% and 32%, when compared with the control cell cultures. At concentration of 7.4 (1.5) μg/mL of this complexes exhibited slightly lower effect of micronucleus for 30% (35%) and 27% (29%), when compared with the control cell cultures. © RASĀYAN. All rights reserved.
T2  - Rasayan Journal of Chemistry
T1  - Cytokinesis block micronucleus assay in human lymphocytes after exposure to Ru(III) thiosemicarbazone complexes in vitro
VL  - 11
IS  - 2
SP  - 647
EP  - 652
DO  - 10.31788/rjc.2018.1123004
ER  - 

@article{
author = "Ljubijankić, Nevzeta and Stanković, Miomir and Tešević, Vele and Grgurić-Šipka, Sanja and Jadranin, Milka and Begić, Sabina and Šabanović, Elma",
year = "2018",
abstract = "This study evaluates the genotoxic potential of two Ru(III) complexes with thiosemicarbazone based ligands. The complexes were tested for in vitro protective effect on chromosome aberrations in peripheral human lymphocytes using the cytokinesis block micronucleus (CBMN) assay at concentrations 1.5; 3.7 and 7.4 μg/mL. The cell culture treated with the tested complexes, at 3.7 μg/mL concentration, decreased a frequency of micronucleus for 37% and 32%, when compared with the control cell cultures. At concentration of 7.4 (1.5) μg/mL of this complexes exhibited slightly lower effect of micronucleus for 30% (35%) and 27% (29%), when compared with the control cell cultures. © RASĀYAN. All rights reserved.",
journal = "Rasayan Journal of Chemistry",
title = "Cytokinesis block micronucleus assay in human lymphocytes after exposure to Ru(III) thiosemicarbazone complexes in vitro",
volume = "11",
number = "2",
pages = "647-652",
doi = "10.31788/rjc.2018.1123004"
}

Ljubijankić, N., Stanković, M., Tešević, V., Grgurić-Šipka, S., Jadranin, M., Begić, S.,& Šabanović, E.. (2018). Cytokinesis block micronucleus assay in human lymphocytes after exposure to Ru(III) thiosemicarbazone complexes in vitro. in Rasayan Journal of Chemistry, 11(2), 647-652.
https://doi.org/10.31788/rjc.2018.1123004

Ljubijankić N, Stanković M, Tešević V, Grgurić-Šipka S, Jadranin M, Begić S, Šabanović E. Cytokinesis block micronucleus assay in human lymphocytes after exposure to Ru(III) thiosemicarbazone complexes in vitro. in Rasayan Journal of Chemistry. 2018;11(2):647-652.
doi:10.31788/rjc.2018.1123004 .

Ljubijankić, Nevzeta, Stanković, Miomir, Tešević, Vele, Grgurić-Šipka, Sanja, Jadranin, Milka, Begić, Sabina, Šabanović, Elma, "Cytokinesis block micronucleus assay in human lymphocytes after exposure to Ru(III) thiosemicarbazone complexes in vitro" in Rasayan Journal of Chemistry, 11, no. 2 (2018):647-652,
https://doi.org/10.31788/rjc.2018.1123004 . .