TY  - JOUR
AU  - Đurašinović, Tatjana
AU  - Lopandić, Zorana
AU  - Protić-Rosić, Isidora
AU  - Nešić, Andrijana
AU  - Trbojević-Ivić, Jovana
AU  - Jappe, Uta
AU  - Gavrović-Jankulović, Marija
PY  - 2024
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6338
AB  - Banana allergy is often associated with the pollen and latex allergies, which led us to the  hypothesis that some yet unidentified banana allergen could provide a basis of the latex-pollen-fruit syndrome. S-adenosyl-L-homocysteine hydrolase (SAHH) was recently identified in the literature as a novel plant allergen. This study aimed to assess the allergenic potential of the naturally occurring banana SAHH (nSAHH) and its recombinant homolog produced in E. coli (rSAHH). nSAHH showed IgE reactivity with a serum pool of twelve banana-allergic persons,
while rSAHH displayed IgE reactivity in ten out of the twelve tested patients. Five linear B-cell epitopes were identified on the rSAHH surface, exhibiting ≥ 90 % sequence homology with relevant plant SAHH allergens. Our findings have elucidated SAHH as a novel plant panallergen, underlying the cross-reactivity between plant derived food and respiratory allergens, confirming our initial hypothesis.
PB  - Elsevier
T2  - Food Chemistry
T1  - Identification of S-adenosyl-L-homocysteine hydrolase from banana fruit as a novel plant panallergen
VL  - 437
SP  - 137782
DO  - 10.1016/j.foodchem.2023.137782
ER  - 

@article{
author = "Đurašinović, Tatjana and Lopandić, Zorana and Protić-Rosić, Isidora and Nešić, Andrijana and Trbojević-Ivić, Jovana and Jappe, Uta and Gavrović-Jankulović, Marija",
year = "2024",
abstract = "Banana allergy is often associated with the pollen and latex allergies, which led us to the  hypothesis that some yet unidentified banana allergen could provide a basis of the latex-pollen-fruit syndrome. S-adenosyl-L-homocysteine hydrolase (SAHH) was recently identified in the literature as a novel plant allergen. This study aimed to assess the allergenic potential of the naturally occurring banana SAHH (nSAHH) and its recombinant homolog produced in E. coli (rSAHH). nSAHH showed IgE reactivity with a serum pool of twelve banana-allergic persons,
while rSAHH displayed IgE reactivity in ten out of the twelve tested patients. Five linear B-cell epitopes were identified on the rSAHH surface, exhibiting ≥ 90 % sequence homology with relevant plant SAHH allergens. Our findings have elucidated SAHH as a novel plant panallergen, underlying the cross-reactivity between plant derived food and respiratory allergens, confirming our initial hypothesis.",
publisher = "Elsevier",
journal = "Food Chemistry",
title = "Identification of S-adenosyl-L-homocysteine hydrolase from banana fruit as a novel plant panallergen",
volume = "437",
pages = "137782",
doi = "10.1016/j.foodchem.2023.137782"
}

Đurašinović, T., Lopandić, Z., Protić-Rosić, I., Nešić, A., Trbojević-Ivić, J., Jappe, U.,& Gavrović-Jankulović, M.. (2024). Identification of S-adenosyl-L-homocysteine hydrolase from banana fruit as a novel plant panallergen. in Food Chemistry
Elsevier., 437, 137782.
https://doi.org/10.1016/j.foodchem.2023.137782

Đurašinović T, Lopandić Z, Protić-Rosić I, Nešić A, Trbojević-Ivić J, Jappe U, Gavrović-Jankulović M. Identification of S-adenosyl-L-homocysteine hydrolase from banana fruit as a novel plant panallergen. in Food Chemistry. 2024;437:137782.
doi:10.1016/j.foodchem.2023.137782 .

Đurašinović, Tatjana, Lopandić, Zorana, Protić-Rosić, Isidora, Nešić, Andrijana, Trbojević-Ivić, Jovana, Jappe, Uta, Gavrović-Jankulović, Marija, "Identification of S-adenosyl-L-homocysteine hydrolase from banana fruit as a novel plant panallergen" in Food Chemistry, 437 (2024):137782,
https://doi.org/10.1016/j.foodchem.2023.137782 . .

TY  - JOUR
AU  - Knežević, Sara
AU  - Ognjanović, Miloš
AU  - Gavrović-Jankulović, Marija
AU  - Đurašinović, Tatjana
AU  - Antić, Bratislav
AU  - Vranješ-Đurić, Sanja
AU  - Stanković, Dalibor
PY  - 2022
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4720
AB  - S-Adenosyl-L-Homocysteine (AdoHcy) is a crucial pathological factor in homocysteine-associated disorders. We developed an impedimetric approach for single drop S-Adenosyl-L-Homocysteine detection, based on S-Adenosyl-L-Homocysteine hydrolase (SAH), produced in the prokaryotic expression system (E. coli) by recombinant DNA technology, immobilized on citrate acid-coated gallium oxyhydroxide dispersed over single-walled carbon nanotubes (CA/GaO(OH)@SWCNT). The proposed biosensor offers detection of AdoHcy, with a limit of detection (LOD) of 0.17 μM. with operating linear range from 1 to 44 μM. The remarkable stability of gallium oxyhydroxide crystal was further improved by citric acid coating and its optical, electrical and physical anisotropy was skipped using SWCNTs.
PB  - Wiley
T2  - Electroanalysis
T1  - S-Adenosyl-L-Homocysteine Hydrolase Immobilized on Citric Acid-capped Gallium Oxyhydroxide on SWCNTs Modified Electrode for AdoHcy Impedimetric Sensing
VL  - 34
IS  - 1
SP  - 15
EP  - 24
DO  - 10.1002/elan.202100362
ER  - 

@article{
author = "Knežević, Sara and Ognjanović, Miloš and Gavrović-Jankulović, Marija and Đurašinović, Tatjana and Antić, Bratislav and Vranješ-Đurić, Sanja and Stanković, Dalibor",
year = "2022",
abstract = "S-Adenosyl-L-Homocysteine (AdoHcy) is a crucial pathological factor in homocysteine-associated disorders. We developed an impedimetric approach for single drop S-Adenosyl-L-Homocysteine detection, based on S-Adenosyl-L-Homocysteine hydrolase (SAH), produced in the prokaryotic expression system (E. coli) by recombinant DNA technology, immobilized on citrate acid-coated gallium oxyhydroxide dispersed over single-walled carbon nanotubes (CA/GaO(OH)@SWCNT). The proposed biosensor offers detection of AdoHcy, with a limit of detection (LOD) of 0.17 μM. with operating linear range from 1 to 44 μM. The remarkable stability of gallium oxyhydroxide crystal was further improved by citric acid coating and its optical, electrical and physical anisotropy was skipped using SWCNTs.",
publisher = "Wiley",
journal = "Electroanalysis",
title = "S-Adenosyl-L-Homocysteine Hydrolase Immobilized on Citric Acid-capped Gallium Oxyhydroxide on SWCNTs Modified Electrode for AdoHcy Impedimetric Sensing",
volume = "34",
number = "1",
pages = "15-24",
doi = "10.1002/elan.202100362"
}

Knežević, S., Ognjanović, M., Gavrović-Jankulović, M., Đurašinović, T., Antić, B., Vranješ-Đurić, S.,& Stanković, D.. (2022). S-Adenosyl-L-Homocysteine Hydrolase Immobilized on Citric Acid-capped Gallium Oxyhydroxide on SWCNTs Modified Electrode for AdoHcy Impedimetric Sensing. in Electroanalysis
Wiley., 34(1), 15-24.
https://doi.org/10.1002/elan.202100362

Knežević S, Ognjanović M, Gavrović-Jankulović M, Đurašinović T, Antić B, Vranješ-Đurić S, Stanković D. S-Adenosyl-L-Homocysteine Hydrolase Immobilized on Citric Acid-capped Gallium Oxyhydroxide on SWCNTs Modified Electrode for AdoHcy Impedimetric Sensing. in Electroanalysis. 2022;34(1):15-24.
doi:10.1002/elan.202100362 .

Knežević, Sara, Ognjanović, Miloš, Gavrović-Jankulović, Marija, Đurašinović, Tatjana, Antić, Bratislav, Vranješ-Đurić, Sanja, Stanković, Dalibor, "S-Adenosyl-L-Homocysteine Hydrolase Immobilized on Citric Acid-capped Gallium Oxyhydroxide on SWCNTs Modified Electrode for AdoHcy Impedimetric Sensing" in Electroanalysis, 34, no. 1 (2022):15-24,
https://doi.org/10.1002/elan.202100362 . .

TY  - CONF
AU  - Đurašinović, Tatjana
AU  - Bazović, Vedrana
AU  - Trbojević-Ivić, Jovana
AU  - Nešić, Andrijana N.
AU  - Gavrović-Jankulović, Marija
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5165
PB  - Belgrade : Faculty of Chemistry
C3  - Proceedings of the Tenth Conference of the Serbian Biochemical Society, Biochemical Insight into Molecular Mechanicms, Serbia
T1  - Screening of potential inhibitors of recombinant S-adenosyl-L-homocysteine hydrolase from banana
SP  - 50
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5165
ER  - 

@conference{
author = "Đurašinović, Tatjana and Bazović, Vedrana and Trbojević-Ivić, Jovana and Nešić, Andrijana N. and Gavrović-Jankulović, Marija",
year = "2021",
publisher = "Belgrade : Faculty of Chemistry",
journal = "Proceedings of the Tenth Conference of the Serbian Biochemical Society, Biochemical Insight into Molecular Mechanicms, Serbia",
title = "Screening of potential inhibitors of recombinant S-adenosyl-L-homocysteine hydrolase from banana",
pages = "50",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5165"
}

Đurašinović, T., Bazović, V., Trbojević-Ivić, J., Nešić, A. N.,& Gavrović-Jankulović, M.. (2021). Screening of potential inhibitors of recombinant S-adenosyl-L-homocysteine hydrolase from banana. in Proceedings of the Tenth Conference of the Serbian Biochemical Society, Biochemical Insight into Molecular Mechanicms, Serbia
Belgrade : Faculty of Chemistry., 50.
https://hdl.handle.net/21.15107/rcub_cherry_5165

Đurašinović T, Bazović V, Trbojević-Ivić J, Nešić AN, Gavrović-Jankulović M. Screening of potential inhibitors of recombinant S-adenosyl-L-homocysteine hydrolase from banana. in Proceedings of the Tenth Conference of the Serbian Biochemical Society, Biochemical Insight into Molecular Mechanicms, Serbia. 2021;:50.
https://hdl.handle.net/21.15107/rcub_cherry_5165 .

Đurašinović, Tatjana, Bazović, Vedrana, Trbojević-Ivić, Jovana, Nešić, Andrijana N., Gavrović-Jankulović, Marija, "Screening of potential inhibitors of recombinant S-adenosyl-L-homocysteine hydrolase from banana" in Proceedings of the Tenth Conference of the Serbian Biochemical Society, Biochemical Insight into Molecular Mechanicms, Serbia (2021):50,
https://hdl.handle.net/21.15107/rcub_cherry_5165 .