TY  - JOUR
AU  - Drazici, Branka
AU  - Popovic, Gordana
AU  - Jelić, Ratomir
AU  - Sladić, Dušan
AU  - Mitić, Dragana
AU  - Anđelković, Katarina K.
AU  - Tešić, Živoslav Lj.
PY  - 2009
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/622
AB  - Acid-base equilibria of Zn(II) and Fe(III) complexes with N',N'(2)-bis-[(1E)-1-(2-pyridyl)ethylidene]ethanedihydrazide (ligand L1) and N',N'(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide (ligand L2), i.e., [Fe(L1)Cl(2)(H(2)O)], [Fe(L2)Cl(H(2)O)](2+), [Zn(L1)(H(2)O)(3)](+) and [Zn(L2)(H(2)O)(2)](2+), which expressed cytotoxic activity, were investigated in aqueous media. The equilibrium constants were determined potentiometrically at 25 degrees C at a constant ionic strength of 0.10 mol/dm(3) (Na(2)SO(4)). The results showed that at pH  lt  8 both the Fe(III) complexes studied here have three, while [Zn(L1)(H(2)O)(3)](+) and [Zn(L2)(H(2)O)(2)](2+) have one and two titratable protons, respectively. Based on the obtained values for the equilibrium constants, protonation schemes of the examined complexes are proposed.
AB  - U ovom radu su proučavane kiselinsko-bazne ravnoteže u vodenim rastvorima kompleksa Zn(II) i Fe(III) sa N',N'2-bis[(1E)-1-(2-piridil)etiliden]etandihidrazidom (ligand L1) i N',N'2-bis[(1E)-1-(2-piridil)etiliden]propandihidrazidom (ligand L2), tj. [Fe(L1)Cl2(H2O)], [Fe(L2)Cl(H2O)]2+, [Zn(L1)(H2O)3]+, [Zn(L2)(H2O)2]2+, koji pokazuju citotoksičnu aktivnost. Ravnotežne konstante su određivane potenciometrijski, na temperaturi 25°C i pri konstantnoj jonskoj jačini 0,10 mol/dm3 Na2SO4. Utvrđeno je da u intervalu pH  lt  8 ispitivani Fe(III) kompleksi imaju tri, [Zn(L1)(H2O)3]+ jedan, a [Zn(L2)(H2O)2]2+ dva protona koji mogu da se titrišu. Na osnovu dobijenih vrednosti za konstante, pretpostavljene su i odgovarajuće protonacione sheme.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Acid-base equilibria of the Zn(II) and Fe(III) complexes with condensation products of 2-acetylpyridine and the dihydrazide of oxalic and malonic acid
T1  - Kiselinsko-bazne ravnoteže kompleksa Fe(III) i Zn(II) sa kondenzacionim derivatima 2-acetilpiridina i hidrazida oksalne, odnosno malonske kiseline
VL  - 74
IS  - 3
SP  - 269
EP  - 277
DO  - 10.2298/JSC0903269D
ER  - 

@article{
author = "Drazici, Branka and Popovic, Gordana and Jelić, Ratomir and Sladić, Dušan and Mitić, Dragana and Anđelković, Katarina K. and Tešić, Živoslav Lj.",
year = "2009",
abstract = "Acid-base equilibria of Zn(II) and Fe(III) complexes with N',N'(2)-bis-[(1E)-1-(2-pyridyl)ethylidene]ethanedihydrazide (ligand L1) and N',N'(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide (ligand L2), i.e., [Fe(L1)Cl(2)(H(2)O)], [Fe(L2)Cl(H(2)O)](2+), [Zn(L1)(H(2)O)(3)](+) and [Zn(L2)(H(2)O)(2)](2+), which expressed cytotoxic activity, were investigated in aqueous media. The equilibrium constants were determined potentiometrically at 25 degrees C at a constant ionic strength of 0.10 mol/dm(3) (Na(2)SO(4)). The results showed that at pH  lt  8 both the Fe(III) complexes studied here have three, while [Zn(L1)(H(2)O)(3)](+) and [Zn(L2)(H(2)O)(2)](2+) have one and two titratable protons, respectively. Based on the obtained values for the equilibrium constants, protonation schemes of the examined complexes are proposed., U ovom radu su proučavane kiselinsko-bazne ravnoteže u vodenim rastvorima kompleksa Zn(II) i Fe(III) sa N',N'2-bis[(1E)-1-(2-piridil)etiliden]etandihidrazidom (ligand L1) i N',N'2-bis[(1E)-1-(2-piridil)etiliden]propandihidrazidom (ligand L2), tj. [Fe(L1)Cl2(H2O)], [Fe(L2)Cl(H2O)]2+, [Zn(L1)(H2O)3]+, [Zn(L2)(H2O)2]2+, koji pokazuju citotoksičnu aktivnost. Ravnotežne konstante su određivane potenciometrijski, na temperaturi 25°C i pri konstantnoj jonskoj jačini 0,10 mol/dm3 Na2SO4. Utvrđeno je da u intervalu pH  lt  8 ispitivani Fe(III) kompleksi imaju tri, [Zn(L1)(H2O)3]+ jedan, a [Zn(L2)(H2O)2]2+ dva protona koji mogu da se titrišu. Na osnovu dobijenih vrednosti za konstante, pretpostavljene su i odgovarajuće protonacione sheme.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Acid-base equilibria of the Zn(II) and Fe(III) complexes with condensation products of 2-acetylpyridine and the dihydrazide of oxalic and malonic acid, Kiselinsko-bazne ravnoteže kompleksa Fe(III) i Zn(II) sa kondenzacionim derivatima 2-acetilpiridina i hidrazida oksalne, odnosno malonske kiseline",
volume = "74",
number = "3",
pages = "269-277",
doi = "10.2298/JSC0903269D"
}

Drazici, B., Popovic, G., Jelić, R., Sladić, D., Mitić, D., Anđelković, K. K.,& Tešić, Ž. Lj.. (2009). Acid-base equilibria of the Zn(II) and Fe(III) complexes with condensation products of 2-acetylpyridine and the dihydrazide of oxalic and malonic acid. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 74(3), 269-277.
https://doi.org/10.2298/JSC0903269D

Drazici B, Popovic G, Jelić R, Sladić D, Mitić D, Anđelković KK, Tešić ŽL. Acid-base equilibria of the Zn(II) and Fe(III) complexes with condensation products of 2-acetylpyridine and the dihydrazide of oxalic and malonic acid. in Journal of the Serbian Chemical Society. 2009;74(3):269-277.
doi:10.2298/JSC0903269D .

Drazici, Branka, Popovic, Gordana, Jelić, Ratomir, Sladić, Dušan, Mitić, Dragana, Anđelković, Katarina K., Tešić, Živoslav Lj., "Acid-base equilibria of the Zn(II) and Fe(III) complexes with condensation products of 2-acetylpyridine and the dihydrazide of oxalic and malonic acid" in Journal of the Serbian Chemical Society, 74, no. 3 (2009):269-277,
https://doi.org/10.2298/JSC0903269D . .