TY  - JOUR
AU  - Kojadinović, Milica I.
AU  - Glibetić, Marija D.
AU  - Vučić, Vesna M.
AU  - Popović, Milica M.
AU  - Vidović, Nevena Đ.
AU  - Debeljak-Martačić, Jasmina D.
AU  - Arsić, Aleksandra Č.
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4791
AB  - Pomegranate juice (PJ) has potential positive effects in patients with metabolic disturbances due to a high content of polyphenols. The objective of this study was to evaluate effects of a 2-week consumption of dietary doses of PJ on blood pressure, lipid metabolism, and oxidative stress markers in overweight patients with dyslipidemia. Twenty-four patients, 8 males and 16 females, 40-60 years of age, with established overweight and dyslipidemia were randomly assigned into intervention group, who consumed 300 mL of PJ daily for 2 weeks, or control group. After 2 weeks of juice intake, intervention group had significantly lower diastolic blood pressure, low-density lipoprotein cholesterol, aminotransferase, and activity of glutathione peroxidase. Furthermore, patients who consumed PJ had reduced percentage of docosahexaenoic acid (22:6n-3, DHA) in plasma phospholipids and increased estimated activity of stearoyl-CoA desaturase. In erythrocytes, we found a significant increase in the levels of dihomo-gamma- linolenic acid (20:3n-6, DGLA) and DHA, as well as in estimated activity of Delta 6 desaturase, and a decrease in estimated activity of Delta 5 desaturase. These results show that even a short-term consumption of dietary doses of PJ exerts beneficial effects and affects lipid metabolism in overweight patients with dyslipidemia.
PB  - Mary Ann Liebert, Inc, New Rochelle
T2  - Journal of Medicinal Food
T1  - Short-Term Consumption of Pomegranate Juice Alleviates Some Metabolic Disturbances in Overweight Patients with Dyslipidemia
VL  - 24
IS  - 9
DO  - 10.1089/jmf.2020.0122
ER  - 

@article{
author = "Kojadinović, Milica I. and Glibetić, Marija D. and Vučić, Vesna M. and Popović, Milica M. and Vidović, Nevena Đ. and Debeljak-Martačić, Jasmina D. and Arsić, Aleksandra Č.",
year = "2021",
abstract = "Pomegranate juice (PJ) has potential positive effects in patients with metabolic disturbances due to a high content of polyphenols. The objective of this study was to evaluate effects of a 2-week consumption of dietary doses of PJ on blood pressure, lipid metabolism, and oxidative stress markers in overweight patients with dyslipidemia. Twenty-four patients, 8 males and 16 females, 40-60 years of age, with established overweight and dyslipidemia were randomly assigned into intervention group, who consumed 300 mL of PJ daily for 2 weeks, or control group. After 2 weeks of juice intake, intervention group had significantly lower diastolic blood pressure, low-density lipoprotein cholesterol, aminotransferase, and activity of glutathione peroxidase. Furthermore, patients who consumed PJ had reduced percentage of docosahexaenoic acid (22:6n-3, DHA) in plasma phospholipids and increased estimated activity of stearoyl-CoA desaturase. In erythrocytes, we found a significant increase in the levels of dihomo-gamma- linolenic acid (20:3n-6, DGLA) and DHA, as well as in estimated activity of Delta 6 desaturase, and a decrease in estimated activity of Delta 5 desaturase. These results show that even a short-term consumption of dietary doses of PJ exerts beneficial effects and affects lipid metabolism in overweight patients with dyslipidemia.",
publisher = "Mary Ann Liebert, Inc, New Rochelle",
journal = "Journal of Medicinal Food",
title = "Short-Term Consumption of Pomegranate Juice Alleviates Some Metabolic Disturbances in Overweight Patients with Dyslipidemia",
volume = "24",
number = "9",
doi = "10.1089/jmf.2020.0122"
}

Kojadinović, M. I., Glibetić, M. D., Vučić, V. M., Popović, M. M., Vidović, N. Đ., Debeljak-Martačić, J. D.,& Arsić, A. Č.. (2021). Short-Term Consumption of Pomegranate Juice Alleviates Some Metabolic Disturbances in Overweight Patients with Dyslipidemia. in Journal of Medicinal Food
Mary Ann Liebert, Inc, New Rochelle., 24(9).
https://doi.org/10.1089/jmf.2020.0122

Kojadinović MI, Glibetić MD, Vučić VM, Popović MM, Vidović NĐ, Debeljak-Martačić JD, Arsić AČ. Short-Term Consumption of Pomegranate Juice Alleviates Some Metabolic Disturbances in Overweight Patients with Dyslipidemia. in Journal of Medicinal Food. 2021;24(9).
doi:10.1089/jmf.2020.0122 .

Kojadinović, Milica I., Glibetić, Marija D., Vučić, Vesna M., Popović, Milica M., Vidović, Nevena Đ., Debeljak-Martačić, Jasmina D., Arsić, Aleksandra Č., "Short-Term Consumption of Pomegranate Juice Alleviates Some Metabolic Disturbances in Overweight Patients with Dyslipidemia" in Journal of Medicinal Food, 24, no. 9 (2021),
https://doi.org/10.1089/jmf.2020.0122 . .