TY  - JOUR
AU  - Grgurić-Šipka, Sanja
AU  - Alshtewi, Mohamed Al. Arbi M.
AU  - Jeremić, Dejan
AU  - Kaluđerović, Goran N.
AU  - Gomez-Ruiz, Santiago
AU  - Žižak, Željko S.
AU  - Juranić, Zorica D.
AU  - Sabo, Tibor
PY  - 2008
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/966
AB  - Two new p-cymene ruthenium(II) complexes containing as additional ligands N-methylpiperazine ([(eta(6)-p-cymene)RuCl2(CH3NH(CH2)(4)NH)]PF6, complex 1) or vitamin K-3-thiosemicarbazone ([(eta(6)-p-cymene)RuCl2(K(3)tsc)], complex 2) were synthesized starting from [(eta(6)-p-cymene)(2)RuCl2](2) and the corresponding ligand. The complexes were characterized by elemental analysis, IR, electronic absorption and NMR spectroscopy. The X-ray crystal structure determination of complex 1 revealed "piano-stool" geometry. The differences in the cytotoxic activity of the two complexes are discussed in terms of the ligand present.
AB  - Sintetisana su dva nova p-cimen-rutenijum(II) kompleksa koji sadrže kao dodatne ligande N-metilpiperazin ([(h6-p-cimen)RuCl2(CH3NH(CH2)4NH)]PF6, kompleks 1) i vitamin K3-tiosemikarbazon ([(h6-p-cimen)RuCl2(K3tsc)], kompleks 2). Oba nova kompleksa dobijena su polazeći od [(h6-p-cimen)2RuCl2]2 kompleksa i odgovarajućeg liganda. Kompleksi su okarakterisani elementalnom analizom, IC, elektronsko-apsorpcionom i NMR spektroskopijom. Rendgeno-strukturna analiza kompleksa 1 pokazala je “piano-stool” geometriju. U zavisnosti od prisutnog liganda diskutovana je razlika u citotoksičnoj aktivnosti ova dva dobijena kompleksa.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Synthesis, structural characterization and cytotoxic activity of two new organoruthenium(II) complexes
T1  - Sinteza, strukturna karakterizacija i citotoksična aktivnost dva nova organorutenijum(II) kompleksa
VL  - 73
IS  - 6
SP  - 619
EP  - 630
DO  - 10.2298/JSC0806619G
ER  - 

@article{
author = "Grgurić-Šipka, Sanja and Alshtewi, Mohamed Al. Arbi M. and Jeremić, Dejan and Kaluđerović, Goran N. and Gomez-Ruiz, Santiago and Žižak, Željko S. and Juranić, Zorica D. and Sabo, Tibor",
year = "2008",
abstract = "Two new p-cymene ruthenium(II) complexes containing as additional ligands N-methylpiperazine ([(eta(6)-p-cymene)RuCl2(CH3NH(CH2)(4)NH)]PF6, complex 1) or vitamin K-3-thiosemicarbazone ([(eta(6)-p-cymene)RuCl2(K(3)tsc)], complex 2) were synthesized starting from [(eta(6)-p-cymene)(2)RuCl2](2) and the corresponding ligand. The complexes were characterized by elemental analysis, IR, electronic absorption and NMR spectroscopy. The X-ray crystal structure determination of complex 1 revealed "piano-stool" geometry. The differences in the cytotoxic activity of the two complexes are discussed in terms of the ligand present., Sintetisana su dva nova p-cimen-rutenijum(II) kompleksa koji sadrže kao dodatne ligande N-metilpiperazin ([(h6-p-cimen)RuCl2(CH3NH(CH2)4NH)]PF6, kompleks 1) i vitamin K3-tiosemikarbazon ([(h6-p-cimen)RuCl2(K3tsc)], kompleks 2). Oba nova kompleksa dobijena su polazeći od [(h6-p-cimen)2RuCl2]2 kompleksa i odgovarajućeg liganda. Kompleksi su okarakterisani elementalnom analizom, IC, elektronsko-apsorpcionom i NMR spektroskopijom. Rendgeno-strukturna analiza kompleksa 1 pokazala je “piano-stool” geometriju. U zavisnosti od prisutnog liganda diskutovana je razlika u citotoksičnoj aktivnosti ova dva dobijena kompleksa.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Synthesis, structural characterization and cytotoxic activity of two new organoruthenium(II) complexes, Sinteza, strukturna karakterizacija i citotoksična aktivnost dva nova organorutenijum(II) kompleksa",
volume = "73",
number = "6",
pages = "619-630",
doi = "10.2298/JSC0806619G"
}

Grgurić-Šipka, S., Alshtewi, M. Al. A. M., Jeremić, D., Kaluđerović, G. N., Gomez-Ruiz, S., Žižak, Ž. S., Juranić, Z. D.,& Sabo, T.. (2008). Synthesis, structural characterization and cytotoxic activity of two new organoruthenium(II) complexes. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 73(6), 619-630.
https://doi.org/10.2298/JSC0806619G

Grgurić-Šipka S, Alshtewi MAAM, Jeremić D, Kaluđerović GN, Gomez-Ruiz S, Žižak ŽS, Juranić ZD, Sabo T. Synthesis, structural characterization and cytotoxic activity of two new organoruthenium(II) complexes. in Journal of the Serbian Chemical Society. 2008;73(6):619-630.
doi:10.2298/JSC0806619G .

Grgurić-Šipka, Sanja, Alshtewi, Mohamed Al. Arbi M., Jeremić, Dejan, Kaluđerović, Goran N., Gomez-Ruiz, Santiago, Žižak, Željko S., Juranić, Zorica D., Sabo, Tibor, "Synthesis, structural characterization and cytotoxic activity of two new organoruthenium(II) complexes" in Journal of the Serbian Chemical Society, 73, no. 6 (2008):619-630,
https://doi.org/10.2298/JSC0806619G . .