Jakimov, Dimitar

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  • Jakimov, Dimitar (1)
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Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids

Joksović, Milan D.; Bogdanović, Gordana; Kojić, Vesna; Szecsenyi, Katalin Meszaros; Leovac, Vukadin M.; Jakimov, Dimitar; Trifunović, Snežana S.; Marković, Violeta; Joksović, Ljubinka

(Wiley-Blackwell, Malden, 2010)

TY  - JOUR
AU  - Joksović, Milan D.
AU  - Bogdanović, Gordana
AU  - Kojić, Vesna
AU  - Szecsenyi, Katalin Meszaros
AU  - Leovac, Vukadin M.
AU  - Jakimov, Dimitar
AU  - Trifunović, Snežana S.
AU  - Marković, Violeta
AU  - Joksović, Ljubinka
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1097
AB  - New N-[(1,3-diphenylpyrazol-4-yl)methyl]alpha-amino acids (1a-i) have been synthesized and tested in vitro for their antiproliferative activity against human myelogenous leukemia K562, colon adenocarcinoma HT-29, cervix carcinoma HeLa, and normal fetal lung fibroblasts, MRC-5. Compounds derived from both phenylalanine enantiomer precursors appeared to be the most active against myelogenous leukemia K562 cell lines with a high cytotoxic potential.
PB  - Wiley-Blackwell, Malden
T2  - Journal of Heterocyclic Chemistry
T1  - Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids
VL  - 47
IS  - 4
SP  - 850
EP  - 856
DO  - 10.1002/jhet.400
ER  - 
@article{
author = "Joksović, Milan D. and Bogdanović, Gordana and Kojić, Vesna and Szecsenyi, Katalin Meszaros and Leovac, Vukadin M. and Jakimov, Dimitar and Trifunović, Snežana S. and Marković, Violeta and Joksović, Ljubinka",
year = "2010",
abstract = "New N-[(1,3-diphenylpyrazol-4-yl)methyl]alpha-amino acids (1a-i) have been synthesized and tested in vitro for their antiproliferative activity against human myelogenous leukemia K562, colon adenocarcinoma HT-29, cervix carcinoma HeLa, and normal fetal lung fibroblasts, MRC-5. Compounds derived from both phenylalanine enantiomer precursors appeared to be the most active against myelogenous leukemia K562 cell lines with a high cytotoxic potential.",
publisher = "Wiley-Blackwell, Malden",
journal = "Journal of Heterocyclic Chemistry",
title = "Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids",
volume = "47",
number = "4",
pages = "850-856",
doi = "10.1002/jhet.400"
}
Joksović, M. D., Bogdanović, G., Kojić, V., Szecsenyi, K. M., Leovac, V. M., Jakimov, D., Trifunović, S. S., Marković, V.,& Joksović, L.. (2010). Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids. in Journal of Heterocyclic Chemistry
Wiley-Blackwell, Malden., 47(4), 850-856.
https://doi.org/10.1002/jhet.400
Joksović MD, Bogdanović G, Kojić V, Szecsenyi KM, Leovac VM, Jakimov D, Trifunović SS, Marković V, Joksović L. Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids. in Journal of Heterocyclic Chemistry. 2010;47(4):850-856.
doi:10.1002/jhet.400 .
Joksović, Milan D., Bogdanović, Gordana, Kojić, Vesna, Szecsenyi, Katalin Meszaros, Leovac, Vukadin M., Jakimov, Dimitar, Trifunović, Snežana S., Marković, Violeta, Joksović, Ljubinka, "Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids" in Journal of Heterocyclic Chemistry, 47, no. 4 (2010):850-856,
https://doi.org/10.1002/jhet.400 . .
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