TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Pejin, Boris
AU  - Novaković, Miroslav M.
AU  - Stanković, Dalibor
AU  - Mutić, Jelena
AU  - Pajović, Snezana B.
AU  - Tešević, Vele
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2563
AB  - The overall aim of this paper was to compare the multielement composition and antioxidant capacity of two Montenegrin Merlot wines obtained from specific vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011. Elemental composition was analysed using inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS). Additionally, antioxidant capacity was assessed by cyclic voltammetry. VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, all three wines are good source of essential elements and products with a significant antioxidant activity and specific geographical origin.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro
VL  - 32
IS  - 3
SP  - 247
EP  - 251
DO  - 10.1080/14786419.2017.1347171
ER  - 

@article{
author = "Đorđević, Neda O. and Pejin, Boris and Novaković, Miroslav M. and Stanković, Dalibor and Mutić, Jelena and Pajović, Snezana B. and Tešević, Vele",
year = "2018",
abstract = "The overall aim of this paper was to compare the multielement composition and antioxidant capacity of two Montenegrin Merlot wines obtained from specific vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011. Elemental composition was analysed using inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS). Additionally, antioxidant capacity was assessed by cyclic voltammetry. VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, all three wines are good source of essential elements and products with a significant antioxidant activity and specific geographical origin.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro",
volume = "32",
number = "3",
pages = "247-251",
doi = "10.1080/14786419.2017.1347171"
}

Đorđević, N. O., Pejin, B., Novaković, M. M., Stanković, D., Mutić, J., Pajović, S. B.,& Tešević, V.. (2018). Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 32(3), 247-251.
https://doi.org/10.1080/14786419.2017.1347171

Đorđević NO, Pejin B, Novaković MM, Stanković D, Mutić J, Pajović SB, Tešević V. Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro. in Natural Product Research. 2018;32(3):247-251.
doi:10.1080/14786419.2017.1347171 .

Đorđević, Neda O., Pejin, Boris, Novaković, Miroslav M., Stanković, Dalibor, Mutić, Jelena, Pajović, Snezana B., Tešević, Vele, "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro" in Natural Product Research, 32, no. 3 (2018):247-251,
https://doi.org/10.1080/14786419.2017.1347171 . .

TY  - DATA
AU  - Đorđević, Neda O.
AU  - Pejin, Boris
AU  - Novaković, Miroslav M.
AU  - Stanković, Dalibor
AU  - Mutić, Jelena
AU  - Pajović, Snezana B.
AU  - Tešević, Vele
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3016
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Supplementary material for the article: Đorđević, N. O.; Pejin, B.; Novaković, M. M.; Stanković, D. M.; Mutić, J. J.; Pajović, S. B.; Tešević, V. V. Multielement Analysis and Antioxidant Capacity of Merlot Wine Clones Developed in Montenegro. Nat. Prod. Res. 2018, 32 (3), 247–251. https://doi.org/10.1080/14786419.2017.1347171
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3016
ER  - 

@misc{
author = "Đorđević, Neda O. and Pejin, Boris and Novaković, Miroslav M. and Stanković, Dalibor and Mutić, Jelena and Pajović, Snezana B. and Tešević, Vele",
year = "2018",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Supplementary material for the article: Đorđević, N. O.; Pejin, B.; Novaković, M. M.; Stanković, D. M.; Mutić, J. J.; Pajović, S. B.; Tešević, V. V. Multielement Analysis and Antioxidant Capacity of Merlot Wine Clones Developed in Montenegro. Nat. Prod. Res. 2018, 32 (3), 247–251. https://doi.org/10.1080/14786419.2017.1347171",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3016"
}

Đorđević, N. O., Pejin, B., Novaković, M. M., Stanković, D., Mutić, J., Pajović, S. B.,& Tešević, V.. (2018). Supplementary material for the article: Đorđević, N. O.; Pejin, B.; Novaković, M. M.; Stanković, D. M.; Mutić, J. J.; Pajović, S. B.; Tešević, V. V. Multielement Analysis and Antioxidant Capacity of Merlot Wine Clones Developed in Montenegro. Nat. Prod. Res. 2018, 32 (3), 247–251. https://doi.org/10.1080/14786419.2017.1347171. in Natural Product Research
Taylor & Francis Ltd, Abingdon..
https://hdl.handle.net/21.15107/rcub_cherry_3016

Đorđević NO, Pejin B, Novaković MM, Stanković D, Mutić J, Pajović SB, Tešević V. Supplementary material for the article: Đorđević, N. O.; Pejin, B.; Novaković, M. M.; Stanković, D. M.; Mutić, J. J.; Pajović, S. B.; Tešević, V. V. Multielement Analysis and Antioxidant Capacity of Merlot Wine Clones Developed in Montenegro. Nat. Prod. Res. 2018, 32 (3), 247–251. https://doi.org/10.1080/14786419.2017.1347171. in Natural Product Research. 2018;.
https://hdl.handle.net/21.15107/rcub_cherry_3016 .

Đorđević, Neda O., Pejin, Boris, Novaković, Miroslav M., Stanković, Dalibor, Mutić, Jelena, Pajović, Snezana B., Tešević, Vele, "Supplementary material for the article: Đorđević, N. O.; Pejin, B.; Novaković, M. M.; Stanković, D. M.; Mutić, J. J.; Pajović, S. B.; Tešević, V. V. Multielement Analysis and Antioxidant Capacity of Merlot Wine Clones Developed in Montenegro. Nat. Prod. Res. 2018, 32 (3), 247–251. https://doi.org/10.1080/14786419.2017.1347171" in Natural Product Research (2018),
https://hdl.handle.net/21.15107/rcub_cherry_3016 .

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Todorović, Nevena M.
AU  - Novaković, Irena T.
AU  - Pezo, Lato
AU  - Pejin, Boris
AU  - Maras, Vesna
AU  - Tešević, Vele
AU  - Pajović, Snezana B.
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2222
AB  - Screens of antioxidant activity (AA) of various natural products have been a focus of the research community worldwide. This work aimed to differentiate selected samples of Merlot wines originated from Montenegro, with regard to phenolic profile and antioxidant capacity studied by survival rate, total sulfhydryl groups and activities of glutathione peroxidase (GPx), glutathione reductase and catalase in H2O2-stressed Saccharomyces cerevisiae cells. In this study, DPPH assay was also performed. Higher total phenolic content leads to an enhanced AA under both conditions. The same trend was observed for catechin and gallic acid, the most abundant phenolics in the examined wine samples. Finally, the findings of an Artificial Neural Network (ANN) model were in a good agreement (r(2) = 0.978) with the experimental data. All tested samples exhibited a protective effect in H2O2-stressed yeast cells. Pre-treatment with examined wines increased survival in H2O2-stressed cells and shifted antioxidative defense towards GPx-mediated defense. Finally, sensitivity analysis of obtained ANN model highlights the complexity of the impact that variations in the concentrations of specific phenolic components have on the antioxidant defense system.
PB  - Mdpi, Basel
T2  - Molecules
T1  - Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine
VL  - 23
IS  - 8
DO  - 10.3390/molecules23081971
ER  - 

@article{
author = "Đorđević, Neda O. and Todorović, Nevena M. and Novaković, Irena T. and Pezo, Lato and Pejin, Boris and Maras, Vesna and Tešević, Vele and Pajović, Snezana B.",
year = "2018",
abstract = "Screens of antioxidant activity (AA) of various natural products have been a focus of the research community worldwide. This work aimed to differentiate selected samples of Merlot wines originated from Montenegro, with regard to phenolic profile and antioxidant capacity studied by survival rate, total sulfhydryl groups and activities of glutathione peroxidase (GPx), glutathione reductase and catalase in H2O2-stressed Saccharomyces cerevisiae cells. In this study, DPPH assay was also performed. Higher total phenolic content leads to an enhanced AA under both conditions. The same trend was observed for catechin and gallic acid, the most abundant phenolics in the examined wine samples. Finally, the findings of an Artificial Neural Network (ANN) model were in a good agreement (r(2) = 0.978) with the experimental data. All tested samples exhibited a protective effect in H2O2-stressed yeast cells. Pre-treatment with examined wines increased survival in H2O2-stressed cells and shifted antioxidative defense towards GPx-mediated defense. Finally, sensitivity analysis of obtained ANN model highlights the complexity of the impact that variations in the concentrations of specific phenolic components have on the antioxidant defense system.",
publisher = "Mdpi, Basel",
journal = "Molecules",
title = "Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine",
volume = "23",
number = "8",
doi = "10.3390/molecules23081971"
}

Đorđević, N. O., Todorović, N. M., Novaković, I. T., Pezo, L., Pejin, B., Maras, V., Tešević, V.,& Pajović, S. B.. (2018). Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine. in Molecules
Mdpi, Basel., 23(8).
https://doi.org/10.3390/molecules23081971

Đorđević NO, Todorović NM, Novaković IT, Pezo L, Pejin B, Maras V, Tešević V, Pajović SB. Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine. in Molecules. 2018;23(8).
doi:10.3390/molecules23081971 .

Đorđević, Neda O., Todorović, Nevena M., Novaković, Irena T., Pezo, Lato, Pejin, Boris, Maras, Vesna, Tešević, Vele, Pajović, Snezana B., "Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine" in Molecules, 23, no. 8 (2018),
https://doi.org/10.3390/molecules23081971 . .

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Pejin, Boris
AU  - Novaković, Miroslav M.
AU  - Stanković, Dalibor
AU  - Mutić, Jelena
AU  - Pajović, Snezana B.
AU  - Tešević, Vele
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2535
AB  - The overall aim was to compare the quality of two Montenegrin Merlot wines obtained from new vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011, due to preliminary screening of the potential of novel Merlot vine clones for the wine industry. The content of phenolic compounds was determined by liquid chromatography tandem mass spectrometry (LC-MS/MS). Elemental composition was analysed using inductively coupled plasma optical emission spectrometery (ICP-OES) and inductively coupled plasma mass spectrometery (ICP-MS)]. Additionaly, antioxidant capacity was assessed by cyclic voltammetry. Compared with the commercial one, both wine clones contained higher percent of major phenolic compounds (namely, gallic acid and catechin) with top values recorded for VCR1 both in 2010 (30.46 +/- 0.42 mg/1) and 2011 (28.12 +/- 0.29 mg/1). The same wines were enriched with epicatechin, resveratrol, myricetin and quercetin. Furthermore, VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, both new Montenegrin Merlot wines represent good candidates for the commercialised wines with an indication of geographical origin.
PB  - Elsevier Science Bv, Amsterdam
T2  - Scientia Horticulturae
T1  - Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro
VL  - 225
SP  - 505
EP  - 511
DO  - 10.1016/j.scienta.2017.07.045
ER  - 

@article{
author = "Đorđević, Neda O. and Pejin, Boris and Novaković, Miroslav M. and Stanković, Dalibor and Mutić, Jelena and Pajović, Snezana B. and Tešević, Vele",
year = "2017",
abstract = "The overall aim was to compare the quality of two Montenegrin Merlot wines obtained from new vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011, due to preliminary screening of the potential of novel Merlot vine clones for the wine industry. The content of phenolic compounds was determined by liquid chromatography tandem mass spectrometry (LC-MS/MS). Elemental composition was analysed using inductively coupled plasma optical emission spectrometery (ICP-OES) and inductively coupled plasma mass spectrometery (ICP-MS)]. Additionaly, antioxidant capacity was assessed by cyclic voltammetry. Compared with the commercial one, both wine clones contained higher percent of major phenolic compounds (namely, gallic acid and catechin) with top values recorded for VCR1 both in 2010 (30.46 +/- 0.42 mg/1) and 2011 (28.12 +/- 0.29 mg/1). The same wines were enriched with epicatechin, resveratrol, myricetin and quercetin. Furthermore, VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, both new Montenegrin Merlot wines represent good candidates for the commercialised wines with an indication of geographical origin.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Scientia Horticulturae",
title = "Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro",
volume = "225",
pages = "505-511",
doi = "10.1016/j.scienta.2017.07.045"
}

Đorđević, N. O., Pejin, B., Novaković, M. M., Stanković, D., Mutić, J., Pajović, S. B.,& Tešević, V.. (2017). Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro. in Scientia Horticulturae
Elsevier Science Bv, Amsterdam., 225, 505-511.
https://doi.org/10.1016/j.scienta.2017.07.045

Đorđević NO, Pejin B, Novaković MM, Stanković D, Mutić J, Pajović SB, Tešević V. Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro. in Scientia Horticulturae. 2017;225:505-511.
doi:10.1016/j.scienta.2017.07.045 .

Đorđević, Neda O., Pejin, Boris, Novaković, Miroslav M., Stanković, Dalibor, Mutić, Jelena, Pajović, Snezana B., Tešević, Vele, "Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro" in Scientia Horticulturae, 225 (2017):505-511,
https://doi.org/10.1016/j.scienta.2017.07.045 . .

TY  - DATA
AU  - Đorđević, Neda O.
AU  - Novaković, Miroslav M.
AU  - Pejin, Boris
AU  - Mutić, Jelena
AU  - Vajs, Vlatka
AU  - Pajović, Snezana B.
AU  - Tešević, Vele
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3028
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Supplementary data for article: Đorđevic, N. O.; Novaković, M. M.; Pejin, B.; Mutić, J.; Vajs, V.; Pajovic, S. B.; Tešević, V. Comparative Analytical Study of the Selected Wine Varieties Grown in Montenegro. Natural Product Research 2017, 31 (15), 1825–1830. https://doi.org/10.1080/14786419.2017.1289209
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3028
ER  - 

@misc{
author = "Đorđević, Neda O. and Novaković, Miroslav M. and Pejin, Boris and Mutić, Jelena and Vajs, Vlatka and Pajović, Snezana B. and Tešević, Vele",
year = "2017",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Supplementary data for article: Đorđevic, N. O.; Novaković, M. M.; Pejin, B.; Mutić, J.; Vajs, V.; Pajovic, S. B.; Tešević, V. Comparative Analytical Study of the Selected Wine Varieties Grown in Montenegro. Natural Product Research 2017, 31 (15), 1825–1830. https://doi.org/10.1080/14786419.2017.1289209",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3028"
}

Đorđević, N. O., Novaković, M. M., Pejin, B., Mutić, J., Vajs, V., Pajović, S. B.,& Tešević, V.. (2017). Supplementary data for article: Đorđevic, N. O.; Novaković, M. M.; Pejin, B.; Mutić, J.; Vajs, V.; Pajovic, S. B.; Tešević, V. Comparative Analytical Study of the Selected Wine Varieties Grown in Montenegro. Natural Product Research 2017, 31 (15), 1825–1830. https://doi.org/10.1080/14786419.2017.1289209. in Natural Product Research
Taylor & Francis Ltd, Abingdon..
https://hdl.handle.net/21.15107/rcub_cherry_3028

Đorđević NO, Novaković MM, Pejin B, Mutić J, Vajs V, Pajović SB, Tešević V. Supplementary data for article: Đorđevic, N. O.; Novaković, M. M.; Pejin, B.; Mutić, J.; Vajs, V.; Pajovic, S. B.; Tešević, V. Comparative Analytical Study of the Selected Wine Varieties Grown in Montenegro. Natural Product Research 2017, 31 (15), 1825–1830. https://doi.org/10.1080/14786419.2017.1289209. in Natural Product Research. 2017;.
https://hdl.handle.net/21.15107/rcub_cherry_3028 .

Đorđević, Neda O., Novaković, Miroslav M., Pejin, Boris, Mutić, Jelena, Vajs, Vlatka, Pajović, Snezana B., Tešević, Vele, "Supplementary data for article: Đorđevic, N. O.; Novaković, M. M.; Pejin, B.; Mutić, J.; Vajs, V.; Pajovic, S. B.; Tešević, V. Comparative Analytical Study of the Selected Wine Varieties Grown in Montenegro. Natural Product Research 2017, 31 (15), 1825–1830. https://doi.org/10.1080/14786419.2017.1289209" in Natural Product Research (2017),
https://hdl.handle.net/21.15107/rcub_cherry_3028 .

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Novaković, Miroslav M.
AU  - Pejin, Boris
AU  - Mutić, Jelena
AU  - Vajs, Vlatka
AU  - Pajović, Snezana B.
AU  - Tešević, Vele
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2481
AB  - Samples of the selected red wine varieties grown in Montenegro (Merlot, Cabernet Sauvignon and Vranac; vintages 2010-2012) were compared according to total phenolic content, anti-DPPH radical activity, phenolic profile and elemental composition. All the samples showed profound anti-DPPH radical activity, due to high content of total phenolic compounds (R=0.92). The most abundant phenolics were catechin and gallic acid with the highest values recorded for Merlot 2012 (43.22 and 28.65mg/L, respectively). In addition to this, the content of essential elements including the potentially toxic ones was within healthy (safe) level for all the samples analysed. This study has actually pointed out Merlot wine variety as the best quality one, though all three varieties may be used as safe and health-promoting nutritional products. [GRAPHICS] .
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Comparative analytical study of the selected wine varieties grown in Montenegro
VL  - 31
IS  - 15
SP  - 1825
EP  - 1830
DO  - 10.1080/14786419.2017.1289209
ER  - 

@article{
author = "Đorđević, Neda O. and Novaković, Miroslav M. and Pejin, Boris and Mutić, Jelena and Vajs, Vlatka and Pajović, Snezana B. and Tešević, Vele",
year = "2017",
abstract = "Samples of the selected red wine varieties grown in Montenegro (Merlot, Cabernet Sauvignon and Vranac; vintages 2010-2012) were compared according to total phenolic content, anti-DPPH radical activity, phenolic profile and elemental composition. All the samples showed profound anti-DPPH radical activity, due to high content of total phenolic compounds (R=0.92). The most abundant phenolics were catechin and gallic acid with the highest values recorded for Merlot 2012 (43.22 and 28.65mg/L, respectively). In addition to this, the content of essential elements including the potentially toxic ones was within healthy (safe) level for all the samples analysed. This study has actually pointed out Merlot wine variety as the best quality one, though all three varieties may be used as safe and health-promoting nutritional products. [GRAPHICS] .",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Comparative analytical study of the selected wine varieties grown in Montenegro",
volume = "31",
number = "15",
pages = "1825-1830",
doi = "10.1080/14786419.2017.1289209"
}

Đorđević, N. O., Novaković, M. M., Pejin, B., Mutić, J., Vajs, V., Pajović, S. B.,& Tešević, V.. (2017). Comparative analytical study of the selected wine varieties grown in Montenegro. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 31(15), 1825-1830.
https://doi.org/10.1080/14786419.2017.1289209

Đorđević NO, Novaković MM, Pejin B, Mutić J, Vajs V, Pajović SB, Tešević V. Comparative analytical study of the selected wine varieties grown in Montenegro. in Natural Product Research. 2017;31(15):1825-1830.
doi:10.1080/14786419.2017.1289209 .

Đorđević, Neda O., Novaković, Miroslav M., Pejin, Boris, Mutić, Jelena, Vajs, Vlatka, Pajović, Snezana B., Tešević, Vele, "Comparative analytical study of the selected wine varieties grown in Montenegro" in Natural Product Research, 31, no. 15 (2017):1825-1830,
https://doi.org/10.1080/14786419.2017.1289209 . .

TY  - JOUR
AU  - Filipović, Dragana
AU  - Mandić, Ljuba M.
AU  - Kanazir, Dusan
AU  - Pajović, Snezana B.
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1072
AB  - Cellular protection against oxidative stress is afforded by the enzyme superoxide dismutase (SOD). In this study, the protein levels of copper-zinc SOD (CuZnSOD) in the cytosolic and nuclear fraction, manganese SOD (MnSOD) in the mitochondrial, and cytosolic fraction and cytochrome c (cyt c) in the liver of male rats exposed to 2 h of acute immobilization (IM) or Cold stress, 21 days chronic isolation or their combinations (chronic/acute stress) were examined. The serum corticosterone (CORT) level was measured, as an indicator of stress stimuli. Both acute stressors with elevated CORT levels caused a decrease of mitochondrial MnSOD, while acute IM resulted in redistribution of the CuZnSOD protein level between the cytosolic and nuclear fraction. Chronic isolation, during which the CORT level was close to control value, resulted in an increase of cytosolic CuZnSOD, whereas a decrease of MnSOD in mitochondrial and its corresponding increase in cytosol fraction was found. In both combined stress regimes, an increase of the CuZnSOD and MnSOD levels in the cytosolic fraction was recorded whereby increase of the CORT level was observed only in the chronic isolation followed by acute IM. The data indicate that acute and/or chronic stress models have different degrees of influence on serum CORT and SOD subcellular protein levels. Increased cytosolic CuZnSOD protein level under chronic isolation suggests that state of oxidative stress may also exist under CORT level similar to the basal value. The presence of MnSOD and cyt c in the cytosolic fraction could serve as useful parameters for mitochondrial dysfunction.
PB  - Springer, Dordrecht
T2  - Molecular and Cellular Biochemistry
T1  - Acute and/or chronic stress models modulate CuZnSOD and MnSOD protein expression in rat liver
VL  - 338
IS  - 1-2
SP  - 167
EP  - 174
DO  - 10.1007/s11010-009-0350-8
ER  - 

@article{
author = "Filipović, Dragana and Mandić, Ljuba M. and Kanazir, Dusan and Pajović, Snezana B.",
year = "2010",
abstract = "Cellular protection against oxidative stress is afforded by the enzyme superoxide dismutase (SOD). In this study, the protein levels of copper-zinc SOD (CuZnSOD) in the cytosolic and nuclear fraction, manganese SOD (MnSOD) in the mitochondrial, and cytosolic fraction and cytochrome c (cyt c) in the liver of male rats exposed to 2 h of acute immobilization (IM) or Cold stress, 21 days chronic isolation or their combinations (chronic/acute stress) were examined. The serum corticosterone (CORT) level was measured, as an indicator of stress stimuli. Both acute stressors with elevated CORT levels caused a decrease of mitochondrial MnSOD, while acute IM resulted in redistribution of the CuZnSOD protein level between the cytosolic and nuclear fraction. Chronic isolation, during which the CORT level was close to control value, resulted in an increase of cytosolic CuZnSOD, whereas a decrease of MnSOD in mitochondrial and its corresponding increase in cytosol fraction was found. In both combined stress regimes, an increase of the CuZnSOD and MnSOD levels in the cytosolic fraction was recorded whereby increase of the CORT level was observed only in the chronic isolation followed by acute IM. The data indicate that acute and/or chronic stress models have different degrees of influence on serum CORT and SOD subcellular protein levels. Increased cytosolic CuZnSOD protein level under chronic isolation suggests that state of oxidative stress may also exist under CORT level similar to the basal value. The presence of MnSOD and cyt c in the cytosolic fraction could serve as useful parameters for mitochondrial dysfunction.",
publisher = "Springer, Dordrecht",
journal = "Molecular and Cellular Biochemistry",
title = "Acute and/or chronic stress models modulate CuZnSOD and MnSOD protein expression in rat liver",
volume = "338",
number = "1-2",
pages = "167-174",
doi = "10.1007/s11010-009-0350-8"
}

Filipović, D., Mandić, L. M., Kanazir, D.,& Pajović, S. B.. (2010). Acute and/or chronic stress models modulate CuZnSOD and MnSOD protein expression in rat liver. in Molecular and Cellular Biochemistry
Springer, Dordrecht., 338(1-2), 167-174.
https://doi.org/10.1007/s11010-009-0350-8

Filipović D, Mandić LM, Kanazir D, Pajović SB. Acute and/or chronic stress models modulate CuZnSOD and MnSOD protein expression in rat liver. in Molecular and Cellular Biochemistry. 2010;338(1-2):167-174.
doi:10.1007/s11010-009-0350-8 .

Filipović, Dragana, Mandić, Ljuba M., Kanazir, Dusan, Pajović, Snezana B., "Acute and/or chronic stress models modulate CuZnSOD and MnSOD protein expression in rat liver" in Molecular and Cellular Biochemistry, 338, no. 1-2 (2010):167-174,
https://doi.org/10.1007/s11010-009-0350-8 . .