TY  - JOUR
AU  - Đurović, Saša
AU  - Micić, Darko
AU  - Šorgić, Saša
AU  - Popov, Saša
AU  - Gašić, Uroš M.
AU  - Tosti, Tomislav
AU  - Kostić, Marija
AU  - Smyatskaya, Yulia A.
AU  - Blagojević, Stevan
AU  - Zeković, Zoran
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6183
AB  - Stinging nettle (SN) is an extraordinary plant from the Urticaceae botanical family. It is well-known and widely used in food and folk medicine to treat different disorders and diseases. This article aimed to study the chemical composition of SN leaves extracts, i.e., polyphenolic compounds and vitamins B and C, because many studies ascribed high biological potency to these compounds and their significance in the human diet. Besides the chemical profile, the thermal properties of the extracts were studied. The results confirmed presence of many polyphenolic compounds and vitamins B and C. It also showed that the chemical profile closely correlated with the applied extraction technique. The thermal analysis showed that analyzed samples were thermally stable up to about 160 °C. Thermal degradation of samples UAE, MAE, and MAC took place in four steps, and sample SE in three steps. Altogether, results confirmed the presence of health-beneficial compounds in stinging nettle leaves and indicated the possible application of its extract in pharmaceutical and food industries as both a medicinal and food additive.
PB  - MDPI
T2  - Molecules
T1  - Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts
VL  - 28
IS  - 5
SP  - 2278
DO  - 10.3390/molecules28052278
ER  - 

@article{
author = "Đurović, Saša and Micić, Darko and Šorgić, Saša and Popov, Saša and Gašić, Uroš M. and Tosti, Tomislav and Kostić, Marija and Smyatskaya, Yulia A. and Blagojević, Stevan and Zeković, Zoran",
year = "2023",
abstract = "Stinging nettle (SN) is an extraordinary plant from the Urticaceae botanical family. It is well-known and widely used in food and folk medicine to treat different disorders and diseases. This article aimed to study the chemical composition of SN leaves extracts, i.e., polyphenolic compounds and vitamins B and C, because many studies ascribed high biological potency to these compounds and their significance in the human diet. Besides the chemical profile, the thermal properties of the extracts were studied. The results confirmed presence of many polyphenolic compounds and vitamins B and C. It also showed that the chemical profile closely correlated with the applied extraction technique. The thermal analysis showed that analyzed samples were thermally stable up to about 160 °C. Thermal degradation of samples UAE, MAE, and MAC took place in four steps, and sample SE in three steps. Altogether, results confirmed the presence of health-beneficial compounds in stinging nettle leaves and indicated the possible application of its extract in pharmaceutical and food industries as both a medicinal and food additive.",
publisher = "MDPI",
journal = "Molecules",
title = "Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts",
volume = "28",
number = "5",
pages = "2278",
doi = "10.3390/molecules28052278"
}

Đurović, S., Micić, D., Šorgić, S., Popov, S., Gašić, U. M., Tosti, T., Kostić, M., Smyatskaya, Y. A., Blagojević, S.,& Zeković, Z.. (2023). Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts. in Molecules
MDPI., 28(5), 2278.
https://doi.org/10.3390/molecules28052278

Đurović S, Micić D, Šorgić S, Popov S, Gašić UM, Tosti T, Kostić M, Smyatskaya YA, Blagojević S, Zeković Z. Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts. in Molecules. 2023;28(5):2278.
doi:10.3390/molecules28052278 .

Đurović, Saša, Micić, Darko, Šorgić, Saša, Popov, Saša, Gašić, Uroš M., Tosti, Tomislav, Kostić, Marija, Smyatskaya, Yulia A., Blagojević, Stevan, Zeković, Zoran, "Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts" in Molecules, 28, no. 5 (2023):2278,
https://doi.org/10.3390/molecules28052278 . .

TY  - JOUR
AU  - Veljović, Sonja
AU  - Petrović, Marija
AU  - Jovanović, Marina
AU  - Mitić-Ćulafić, Dragana
AU  - Semen, Tanja Živković
AU  - Kostić, Marija
AU  - Natić, Maja
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6188
AB  - To the best of the author’s knowledge, so far, the utilization of industrial solid Ganoderma lucidum waste was not investigated as a potential source of remaining valuable bioactive compounds. The aim of our study was to chemically characterize the extract prepared with 96% and 70% ethanol utilizing G. lucidum waste from industrial ethanol (GE) and water (GW) extraction. The phenolic profile was assessed by UHPLC-MS/MS, while the amino acid content of selected extracts was done by GC-MS. The chemical composition of the extracts was obtained by ATP-FTIR analysis, and the peak at 1637 cm− 1 of spectra originating from C = O stretching vibration of amide I, was exclusively detected in samples prepared with 70% ethanol. Among eleven amino acids detected in G. lucidum residues, the most abundant was essential amino acid phenylalanine. Phenolic profile revealed p-hydroxybenzoic acid and chlorogenic acid as dominant in all the samples analyzed. The cytotoxic activity against two human cancer cell lines (colon carcinoma (HCT116) and melanoma (Hs294T)), photoprotective activity, and antioxidant activity of G. lucidum residues ethanol extracts (70% and 96%) were examined. The most prominent cytotoxic effect on HCT116 and Hs294T cells was attributed to extract prepared from the water extract production. The sun protection factor (SPF) values of extracts analyzed were found to be in the range from 1.86 (GE96) to 4.80 (GW70). Therefore, G. lucidum solid waste appeared to be a valuable source of bioactive compounds with antioxidant, photoprotective and cytotoxic activities.
T2  - Journal of Food Measurement and Characterization
T1  - Industrial solid wastes from Ganoderma lucidum extract production: chemical characterization and investigation of antioxidant, photoprotective and cytotoxic activities
VL  - 17
IS  - 4
SP  - 3673
EP  - 3682
DO  - 10.1007/s11694-023-01897-6
ER  - 

@article{
author = "Veljović, Sonja and Petrović, Marija and Jovanović, Marina and Mitić-Ćulafić, Dragana and Semen, Tanja Živković and Kostić, Marija and Natić, Maja",
year = "2023",
abstract = "To the best of the author’s knowledge, so far, the utilization of industrial solid Ganoderma lucidum waste was not investigated as a potential source of remaining valuable bioactive compounds. The aim of our study was to chemically characterize the extract prepared with 96% and 70% ethanol utilizing G. lucidum waste from industrial ethanol (GE) and water (GW) extraction. The phenolic profile was assessed by UHPLC-MS/MS, while the amino acid content of selected extracts was done by GC-MS. The chemical composition of the extracts was obtained by ATP-FTIR analysis, and the peak at 1637 cm− 1 of spectra originating from C = O stretching vibration of amide I, was exclusively detected in samples prepared with 70% ethanol. Among eleven amino acids detected in G. lucidum residues, the most abundant was essential amino acid phenylalanine. Phenolic profile revealed p-hydroxybenzoic acid and chlorogenic acid as dominant in all the samples analyzed. The cytotoxic activity against two human cancer cell lines (colon carcinoma (HCT116) and melanoma (Hs294T)), photoprotective activity, and antioxidant activity of G. lucidum residues ethanol extracts (70% and 96%) were examined. The most prominent cytotoxic effect on HCT116 and Hs294T cells was attributed to extract prepared from the water extract production. The sun protection factor (SPF) values of extracts analyzed were found to be in the range from 1.86 (GE96) to 4.80 (GW70). Therefore, G. lucidum solid waste appeared to be a valuable source of bioactive compounds with antioxidant, photoprotective and cytotoxic activities.",
journal = "Journal of Food Measurement and Characterization",
title = "Industrial solid wastes from Ganoderma lucidum extract production: chemical characterization and investigation of antioxidant, photoprotective and cytotoxic activities",
volume = "17",
number = "4",
pages = "3673-3682",
doi = "10.1007/s11694-023-01897-6"
}

Veljović, S., Petrović, M., Jovanović, M., Mitić-Ćulafić, D., Semen, T. Ž., Kostić, M.,& Natić, M.. (2023). Industrial solid wastes from Ganoderma lucidum extract production: chemical characterization and investigation of antioxidant, photoprotective and cytotoxic activities. in Journal of Food Measurement and Characterization, 17(4), 3673-3682.
https://doi.org/10.1007/s11694-023-01897-6

Veljović S, Petrović M, Jovanović M, Mitić-Ćulafić D, Semen TŽ, Kostić M, Natić M. Industrial solid wastes from Ganoderma lucidum extract production: chemical characterization and investigation of antioxidant, photoprotective and cytotoxic activities. in Journal of Food Measurement and Characterization. 2023;17(4):3673-3682.
doi:10.1007/s11694-023-01897-6 .

Veljović, Sonja, Petrović, Marija, Jovanović, Marina, Mitić-Ćulafić, Dragana, Semen, Tanja Živković, Kostić, Marija, Natić, Maja, "Industrial solid wastes from Ganoderma lucidum extract production: chemical characterization and investigation of antioxidant, photoprotective and cytotoxic activities" in Journal of Food Measurement and Characterization, 17, no. 4 (2023):3673-3682,
https://doi.org/10.1007/s11694-023-01897-6 . .