Vujisić, Ljubodrag V.

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Authority KeyName Variants
orcid::0000-0001-7625-7484
  • Vujisić, Ljubodrag V. (95)
Projects
Natural products of wild, cultivated and edible plants: structure and bioactivity determination Ontogenetic characterization of phylogenetic biodiversity
Sekundarni metaboliti samoniklih, lekovitih biljaka: izolovanje, karakterizacija i biloška aktivnost Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200168 (University of Belgrade, Faculty of Chemistry)
Characterization and application of fungal metabolites and assessment of new biofungicides potential Micromorphological, phytochemical and molecular investigations of plants - systematic, ecological and applicative aspects
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200026 (University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM) Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200178 (University of Belgrade, Faculty of Biology)
Diversity of the flora and vegetation of the Central Balkans: Ecology, chorology, and conservation The effects of magnetic fields and other environmental stressors on the physiological responses and behavior of different species
University of Graz Molecular characterization of bacteria from genera Bacillus and Pseudomonas as potential agents for biological control
Novel encapsulation and enzyme technologies for designing of new biocatalysts and biologically active compounds targeting enhancement of food quality, safety and competitiveness Austrian Academy of Sciences at the Institute of Zoology, University of Graz [23811]
Department of Agricultural and Food Sciences, University of Bologna, Italy DOC fellowship of the Austrian Academy of Sciences, at the Institute of Zoology, University of Graz [23811]
Federal Ministry of Education and Science project (the Federation of Bosnia and Herzegovina) [05-39-4362-1/13, 0101-39-145/13] Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200007 (University of Belgrade, Institute for Biological Research 'Siniša Stanković')
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200043 (Institute of Oncology and Radiology of Serbia, Belgrade) Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200053 (University of Belgrade, Institute for Multidisciplinary Research)
Funkcionalna analiza ontogenetske diverzifikacije faune i modifikacije evolutivnih odgovora tokom filogenije Volkswagen Stiftung
Department of Chemistry, University of Houston, 112 Fleming Building, Houston TX 77204- 5003, USA. European Commission
Advancing research in agricultural and food sciences at Faculty of Agriculture, University of Belgrade Holographic methods for generation of specific wave-fronts to better control quantum coherent effects in laser-atom interactions
Molecular mechanisms of redox signalling in homeostasis: adaptation and pathology Study of structure-function relationships in the plant cell wall and modifications of the wall structure by enzyme engineering
Investigation on the medicinal plants: morphological, chemical and pharmacological characterisation The membranes as sites of interaction between the intracellular and apoplastic environments: studies of the bioenergetics and signaling using biophysical and biochemical techniques.

Author's Bibliography

Pygidial glands of the blue ground beetle Carabus intricatus: chemical composition of the secretion and its antimicrobial activity

Vesović, Nikola; Nenadić, Marija; Soković, Marina; Ćirić, Ana; Vujisić, Ljubodrag V.; Todosijević, Marina; Stevanović, Nataša; Perić-Mataruga, Vesna; Ilijin, Larisa; Ćurčić, Srećko

(SpringerLink, 2022)

TY  - JOUR
AU  - Vesović, Nikola
AU  - Nenadić, Marija
AU  - Soković, Marina
AU  - Ćirić, Ana
AU  - Vujisić, Ljubodrag V.
AU  - Todosijević, Marina
AU  - Stevanović, Nataša
AU  - Perić-Mataruga, Vesna
AU  - Ilijin, Larisa
AU  - Ćurčić, Srećko
PY  - 2022
UR  - https://doi.org/10.1007/s00114-022-01790-0
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5183
AB  - Pygidial gland secretions are used as repellent defensive allomones in ground beetles. We provide the first precise data on the chemical composition and antimicrobial potency of the secretion of the blue ground beetle, as well as on the morphology of its pygidial glands. The latter structures were not previously studied chemoecologically and morphologically, and we hypothesized that their secretion may have some antimicrobial action, as is the case with certain Carabus species. Gas chromatography-mass spectrometry (GC-MS) was used to identify methacrylic and angelic acids as dominant chemicals in the secretion from individuals of three populations of the blue ground beetle in Serbia. We tested its secretion against selected strains of medically important microorganisms. The secretion exibits antimicrobial action against certain bacterial species and all tested micromycetes. The most significant antifungal effect of the secretion was against Penicillium ochrochloron, which is more sensitive to the secretion than to commercial antifungal drugs ketoconazole and bifonazole. Bifonazole achieved minimum inhibitory concentrations against Trichoderma viride at more than three times higher value than did the secretion, indicating a significant antifungal effect of the secretion against this micromycete as well. Additionally, we tested commercially available standards of two dominant chemicals in the secretion to investigate their interaction and antimicrobial role in the secretion. Finally, we describe all glandular morpho-functional units of the blue ground beetle. Our results suggest that the secretion of the blue ground beetle may serve not only defensive but also antimicrobial functions, which likely aid the survival of this beetle in the microbial-rich forest litter habitat.
PB  - SpringerLink
T2  - The Science of Nature
T1  - Pygidial glands of the blue ground beetle Carabus intricatus: chemical composition of the secretion and its antimicrobial activity
VL  - 109
IS  - 2
SP  - 19
DO  - 10.1007/s00114-022-01790-0
ER  - 
@article{
author = "Vesović, Nikola and Nenadić, Marija and Soković, Marina and Ćirić, Ana and Vujisić, Ljubodrag V. and Todosijević, Marina and Stevanović, Nataša and Perić-Mataruga, Vesna and Ilijin, Larisa and Ćurčić, Srećko",
year = "2022",
abstract = "Pygidial gland secretions are used as repellent defensive allomones in ground beetles. We provide the first precise data on the chemical composition and antimicrobial potency of the secretion of the blue ground beetle, as well as on the morphology of its pygidial glands. The latter structures were not previously studied chemoecologically and morphologically, and we hypothesized that their secretion may have some antimicrobial action, as is the case with certain Carabus species. Gas chromatography-mass spectrometry (GC-MS) was used to identify methacrylic and angelic acids as dominant chemicals in the secretion from individuals of three populations of the blue ground beetle in Serbia. We tested its secretion against selected strains of medically important microorganisms. The secretion exibits antimicrobial action against certain bacterial species and all tested micromycetes. The most significant antifungal effect of the secretion was against Penicillium ochrochloron, which is more sensitive to the secretion than to commercial antifungal drugs ketoconazole and bifonazole. Bifonazole achieved minimum inhibitory concentrations against Trichoderma viride at more than three times higher value than did the secretion, indicating a significant antifungal effect of the secretion against this micromycete as well. Additionally, we tested commercially available standards of two dominant chemicals in the secretion to investigate their interaction and antimicrobial role in the secretion. Finally, we describe all glandular morpho-functional units of the blue ground beetle. Our results suggest that the secretion of the blue ground beetle may serve not only defensive but also antimicrobial functions, which likely aid the survival of this beetle in the microbial-rich forest litter habitat.",
publisher = "SpringerLink",
journal = "The Science of Nature",
title = "Pygidial glands of the blue ground beetle Carabus intricatus: chemical composition of the secretion and its antimicrobial activity",
volume = "109",
number = "2",
pages = "19",
doi = "10.1007/s00114-022-01790-0"
}
Vesović, N., Nenadić, M., Soković, M., Ćirić, A., Vujisić, L. V., Todosijević, M., Stevanović, N., Perić-Mataruga, V., Ilijin, L.,& Ćurčić, S.. (2022). Pygidial glands of the blue ground beetle Carabus intricatus: chemical composition of the secretion and its antimicrobial activity. in The Science of Nature
SpringerLink., 109(2), 19.
https://doi.org/10.1007/s00114-022-01790-0
Vesović N, Nenadić M, Soković M, Ćirić A, Vujisić LV, Todosijević M, Stevanović N, Perić-Mataruga V, Ilijin L, Ćurčić S. Pygidial glands of the blue ground beetle Carabus intricatus: chemical composition of the secretion and its antimicrobial activity. in The Science of Nature. 2022;109(2):19.
doi:10.1007/s00114-022-01790-0 .
Vesović, Nikola, Nenadić, Marija, Soković, Marina, Ćirić, Ana, Vujisić, Ljubodrag V., Todosijević, Marina, Stevanović, Nataša, Perić-Mataruga, Vesna, Ilijin, Larisa, Ćurčić, Srećko, "Pygidial glands of the blue ground beetle Carabus intricatus: chemical composition of the secretion and its antimicrobial activity" in The Science of Nature, 109, no. 2 (2022):19,
https://doi.org/10.1007/s00114-022-01790-0 . .

To Professor Petar Pfendt, In calidum, et plurium retributivus memoriae: FTIR-ATR analysis of post stamps of the Principality of Serbia issued in 1866 and 1868 and their forgeries

Popović, Aleksandar R.; Anđelković, Boban D.; Đorđević, Dragana S.; Sakan, Sanja M.; Vujisić, Ljubodrag V.; Veličković, Sava; Relić, Dubravka

(2022)

TY  - JOUR
AU  - Popović, Aleksandar R.
AU  - Anđelković, Boban D.
AU  - Đorđević, Dragana S.
AU  - Sakan, Sanja M.
AU  - Vujisić, Ljubodrag V.
AU  - Veličković, Sava
AU  - Relić, Dubravka
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4942
AB  - In order to further define the potential use of FTIR-ATR spectroscopy, as a non-destructive and reliable technique, for the analysis of the characteristics of post stamps, certified originals of the Principality of Serbia stamps (“Prince Michael issues”) issued in 1866 and 1868 as well as their forgeries were ana­lyzed. Spectra enabling the comparison of the paper, dye and glue of stamps of so-called “Vienna issues”, having denominations of 10 (orange-yellow), 20 (pink) and 40 para (blue) and “Belgrade issues” (1 para-green and 2 para-reddish brown), as well as 24 expert-certified forgeries, were taken. It was shown that the applied technology was, in most of the cases, a fast and suitable technique for establishing clear differences between the spectral characteristics of the paper and dye used for the original stamps, and forgeries that were most probably made decades after the printing of the genuine stamps. The differences between print­ings of the same issues of the genuine stamps were also elaborated. It is pro­posed, for the first time in philatelic history, the possibility that “Vienna issues” stamps may have been printed on two different papers, and, having in mind the technology of printing in the 19th century, potentially, not even at the same time or in the same printing house.
T2  - Journal of the Serbian Chemical Society
T1  - To Professor Petar Pfendt, In calidum, et plurium retributivus memoriae: FTIR-ATR analysis of post stamps of the Principality of Serbia issued in 1866 and 1868 and their forgeries
VL  - 87
IS  - 1
SP  - 27
EP  - 40
DO  - 10.2298/JSC210901090P
ER  - 
@article{
author = "Popović, Aleksandar R. and Anđelković, Boban D. and Đorđević, Dragana S. and Sakan, Sanja M. and Vujisić, Ljubodrag V. and Veličković, Sava and Relić, Dubravka",
year = "2022",
abstract = "In order to further define the potential use of FTIR-ATR spectroscopy, as a non-destructive and reliable technique, for the analysis of the characteristics of post stamps, certified originals of the Principality of Serbia stamps (“Prince Michael issues”) issued in 1866 and 1868 as well as their forgeries were ana­lyzed. Spectra enabling the comparison of the paper, dye and glue of stamps of so-called “Vienna issues”, having denominations of 10 (orange-yellow), 20 (pink) and 40 para (blue) and “Belgrade issues” (1 para-green and 2 para-reddish brown), as well as 24 expert-certified forgeries, were taken. It was shown that the applied technology was, in most of the cases, a fast and suitable technique for establishing clear differences between the spectral characteristics of the paper and dye used for the original stamps, and forgeries that were most probably made decades after the printing of the genuine stamps. The differences between print­ings of the same issues of the genuine stamps were also elaborated. It is pro­posed, for the first time in philatelic history, the possibility that “Vienna issues” stamps may have been printed on two different papers, and, having in mind the technology of printing in the 19th century, potentially, not even at the same time or in the same printing house.",
journal = "Journal of the Serbian Chemical Society",
title = "To Professor Petar Pfendt, In calidum, et plurium retributivus memoriae: FTIR-ATR analysis of post stamps of the Principality of Serbia issued in 1866 and 1868 and their forgeries",
volume = "87",
number = "1",
pages = "27-40",
doi = "10.2298/JSC210901090P"
}
Popović, A. R., Anđelković, B. D., Đorđević, D. S., Sakan, S. M., Vujisić, L. V., Veličković, S.,& Relić, D.. (2022). To Professor Petar Pfendt, In calidum, et plurium retributivus memoriae: FTIR-ATR analysis of post stamps of the Principality of Serbia issued in 1866 and 1868 and their forgeries. in Journal of the Serbian Chemical Society, 87(1), 27-40.
https://doi.org/10.2298/JSC210901090P
Popović AR, Anđelković BD, Đorđević DS, Sakan SM, Vujisić LV, Veličković S, Relić D. To Professor Petar Pfendt, In calidum, et plurium retributivus memoriae: FTIR-ATR analysis of post stamps of the Principality of Serbia issued in 1866 and 1868 and their forgeries. in Journal of the Serbian Chemical Society. 2022;87(1):27-40.
doi:10.2298/JSC210901090P .
Popović, Aleksandar R., Anđelković, Boban D., Đorđević, Dragana S., Sakan, Sanja M., Vujisić, Ljubodrag V., Veličković, Sava, Relić, Dubravka, "To Professor Petar Pfendt, In calidum, et plurium retributivus memoriae: FTIR-ATR analysis of post stamps of the Principality of Serbia issued in 1866 and 1868 and their forgeries" in Journal of the Serbian Chemical Society, 87, no. 1 (2022):27-40,
https://doi.org/10.2298/JSC210901090P . .

“Scent of a fruit fly”: Cuticular chemoprofilesafter mating in differently fedDrosophilamelanogaster(Diptera: Drosophilidae) strains

Pavković‐Lučić, Sofija; Trajković, Jelena; Miličić, Dragana; Anđelković, Boban D.; Lučić, Luka; Savić, Tatjana; Vujisić, Ljubodrag V.

(Wiley, 2022)

TY  - JOUR
AU  - Pavković‐Lučić, Sofija
AU  - Trajković, Jelena
AU  - Miličić, Dragana
AU  - Anđelković, Boban D.
AU  - Lučić, Luka
AU  - Savić, Tatjana
AU  - Vujisić, Ljubodrag V.
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5019
AB  - n the world of complex smells in natural environment,feeding and mating represent two important olfactory‐guided behaviors inDrosophila melanogaster(Diptera:Drosophilidae). Diet affects the chemoprofile compositionof the individuals, which, indirectly, may significantly affecttheir mating success. In this study, chemoprofiles of re-cently mated flies belonging to fourD. melanogasterstrains,which were fed for many generations on different sub-strates (standard cornmeal—S strain; banana—B strain;carrot—C strain; tomato—T strain) were identified andquantified. In total, 67 chemical compounds were identi-fied: 48 compounds were extracted from males maintainedon banana and carrot, and 47 compounds from malesmaintained on cornmeal and tomato substrates, while totalof 60 compounds were identified in females from allstrains. The strains and the sexes significantly differed inqualitative nature of their chemoprofiles after mating. Sig-nificant differences in the relative amount of three majormale  pheromones  (cis‐vaccenyl  acetate—cVA,  (Z)‐7‐pentacosene, and (Z)‐7‐tricosene) and in female pheromone(Z,Z)‐7,11‐nonacosadiene among strains were also re-corded. Furthermore, multivariate analysis of variance(MANOVA) pointed to significant differences between irgin and mated individuals of all strains and within bothsexes. Differences in some of the well known sex pher-omones were also identified when comparing their relativeamount before and after mating. The presence of typicalmale pheromones in females, and vice versa may indicatetheir bidirectional transfer during copulation. Our resultsconfirm significant effect of mating status on cuticular hy-drocarbon (CHC) phenotypes in differently fedD. melano-gasterflies.
PB  - Wiley
T2  - Archives of Insect Biochemistry and Physiology
T1  - “Scent of a fruit fly”: Cuticular chemoprofilesafter mating in differently fedDrosophilamelanogaster(Diptera: Drosophilidae) strains
VL  - 109
IS  - 3
SP  - e21866
DO  - 10.1002/arch.21866
ER  - 
@article{
author = "Pavković‐Lučić, Sofija and Trajković, Jelena and Miličić, Dragana and Anđelković, Boban D. and Lučić, Luka and Savić, Tatjana and Vujisić, Ljubodrag V.",
year = "2022",
abstract = "n the world of complex smells in natural environment,feeding and mating represent two important olfactory‐guided behaviors inDrosophila melanogaster(Diptera:Drosophilidae). Diet affects the chemoprofile compositionof the individuals, which, indirectly, may significantly affecttheir mating success. In this study, chemoprofiles of re-cently mated flies belonging to fourD. melanogasterstrains,which were fed for many generations on different sub-strates (standard cornmeal—S strain; banana—B strain;carrot—C strain; tomato—T strain) were identified andquantified. In total, 67 chemical compounds were identi-fied: 48 compounds were extracted from males maintainedon banana and carrot, and 47 compounds from malesmaintained on cornmeal and tomato substrates, while totalof 60 compounds were identified in females from allstrains. The strains and the sexes significantly differed inqualitative nature of their chemoprofiles after mating. Sig-nificant differences in the relative amount of three majormale  pheromones  (cis‐vaccenyl  acetate—cVA,  (Z)‐7‐pentacosene, and (Z)‐7‐tricosene) and in female pheromone(Z,Z)‐7,11‐nonacosadiene among strains were also re-corded. Furthermore, multivariate analysis of variance(MANOVA) pointed to significant differences between irgin and mated individuals of all strains and within bothsexes. Differences in some of the well known sex pher-omones were also identified when comparing their relativeamount before and after mating. The presence of typicalmale pheromones in females, and vice versa may indicatetheir bidirectional transfer during copulation. Our resultsconfirm significant effect of mating status on cuticular hy-drocarbon (CHC) phenotypes in differently fedD. melano-gasterflies.",
publisher = "Wiley",
journal = "Archives of Insect Biochemistry and Physiology",
title = "“Scent of a fruit fly”: Cuticular chemoprofilesafter mating in differently fedDrosophilamelanogaster(Diptera: Drosophilidae) strains",
volume = "109",
number = "3",
pages = "e21866",
doi = "10.1002/arch.21866"
}
Pavković‐Lučić, S., Trajković, J., Miličić, D., Anđelković, B. D., Lučić, L., Savić, T.,& Vujisić, L. V.. (2022). “Scent of a fruit fly”: Cuticular chemoprofilesafter mating in differently fedDrosophilamelanogaster(Diptera: Drosophilidae) strains. in Archives of Insect Biochemistry and Physiology
Wiley., 109(3), e21866.
https://doi.org/10.1002/arch.21866
Pavković‐Lučić S, Trajković J, Miličić D, Anđelković BD, Lučić L, Savić T, Vujisić LV. “Scent of a fruit fly”: Cuticular chemoprofilesafter mating in differently fedDrosophilamelanogaster(Diptera: Drosophilidae) strains. in Archives of Insect Biochemistry and Physiology. 2022;109(3):e21866.
doi:10.1002/arch.21866 .
Pavković‐Lučić, Sofija, Trajković, Jelena, Miličić, Dragana, Anđelković, Boban D., Lučić, Luka, Savić, Tatjana, Vujisić, Ljubodrag V., "“Scent of a fruit fly”: Cuticular chemoprofilesafter mating in differently fedDrosophilamelanogaster(Diptera: Drosophilidae) strains" in Archives of Insect Biochemistry and Physiology, 109, no. 3 (2022):e21866,
https://doi.org/10.1002/arch.21866 . .
4

Inhibition potency of disulphides and trisulphides on various tumor cell lines growth

Mandić, Boris; Simić, K.; Trifunović, S.; Vujisić, Ljubodrag V.; Novaković, M.; Tešević, Vele; Miljanić, O. Š.

(2021)

TY  - JOUR
AU  - Mandić, Boris
AU  - Simić, K.
AU  - Trifunović, S.
AU  - Vujisić, Ljubodrag V.
AU  - Novaković, M.
AU  - Tešević, Vele
AU  - Miljanić, O. Š.
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4936
AB  - Tumor is one of the leading diseases of today. Chemotherapy and radiation therapy healing chances are limited, so some alternative methods are resorted to. Many papers indicated that garlic and organosulphur compounds diallyldisulphide (DADS) and diallyltrisulphide, which are main components of garlic decrease the cancer risk and inhibit the cell proliferation. In this paper inhibition potency of disulphides (DADS and its synthetic analogues) and trisulphides with different alkyl and phenyl substituents on growth of various tumor (Non-Small cell Lung Cancer, Colon cancer, CNS Cancer, Melanoma, Ovarian Cancer, Renal Cancer, Prostate Cancer, Breast Cancer, Leukemia) cell lines was investigated. Concentration of each compound (DADS, diethyl disulphide, dipropyl disulphide, diphenyl disulphide, tetraethylthiuram disulphide (TETUDS), dimetil trisulphide, dipropyl trisulphide and metilpropyl trisulphide (MPTS) was 10 μmol/L. It was found that DADS has an inhibitory effect on the growth of several cancer cell lines, but synthetic analogues TETUDS and MPTS exhibit stronger effect on certain cells lines. MPTS inhibits the growth of even 12 cell lines for more than 10%, especially leukemia cell line SR and NCI-H522 cell line of Non-Small cell Lung Cancer (reduction of growth for 24% and 47%, resp.). Trisulphide analogues exhibit little higher inhibitory effects in comparison to disulphide ones.
T2  - Digest Journal of Nanomaterials & Biostructures (DJNB)
T1  - Inhibition potency of disulphides and trisulphides on various tumor cell lines growth
VL  - 16
IS  - 2
SP  - 585
EP  - 592
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4936
ER  - 
@article{
author = "Mandić, Boris and Simić, K. and Trifunović, S. and Vujisić, Ljubodrag V. and Novaković, M. and Tešević, Vele and Miljanić, O. Š.",
year = "2021",
abstract = "Tumor is one of the leading diseases of today. Chemotherapy and radiation therapy healing chances are limited, so some alternative methods are resorted to. Many papers indicated that garlic and organosulphur compounds diallyldisulphide (DADS) and diallyltrisulphide, which are main components of garlic decrease the cancer risk and inhibit the cell proliferation. In this paper inhibition potency of disulphides (DADS and its synthetic analogues) and trisulphides with different alkyl and phenyl substituents on growth of various tumor (Non-Small cell Lung Cancer, Colon cancer, CNS Cancer, Melanoma, Ovarian Cancer, Renal Cancer, Prostate Cancer, Breast Cancer, Leukemia) cell lines was investigated. Concentration of each compound (DADS, diethyl disulphide, dipropyl disulphide, diphenyl disulphide, tetraethylthiuram disulphide (TETUDS), dimetil trisulphide, dipropyl trisulphide and metilpropyl trisulphide (MPTS) was 10 μmol/L. It was found that DADS has an inhibitory effect on the growth of several cancer cell lines, but synthetic analogues TETUDS and MPTS exhibit stronger effect on certain cells lines. MPTS inhibits the growth of even 12 cell lines for more than 10%, especially leukemia cell line SR and NCI-H522 cell line of Non-Small cell Lung Cancer (reduction of growth for 24% and 47%, resp.). Trisulphide analogues exhibit little higher inhibitory effects in comparison to disulphide ones.",
journal = "Digest Journal of Nanomaterials & Biostructures (DJNB)",
title = "Inhibition potency of disulphides and trisulphides on various tumor cell lines growth",
volume = "16",
number = "2",
pages = "585-592",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4936"
}
Mandić, B., Simić, K., Trifunović, S., Vujisić, L. V., Novaković, M., Tešević, V.,& Miljanić, O. Š.. (2021). Inhibition potency of disulphides and trisulphides on various tumor cell lines growth. in Digest Journal of Nanomaterials & Biostructures (DJNB), 16(2), 585-592.
https://hdl.handle.net/21.15107/rcub_cherry_4936
Mandić B, Simić K, Trifunović S, Vujisić LV, Novaković M, Tešević V, Miljanić OŠ. Inhibition potency of disulphides and trisulphides on various tumor cell lines growth. in Digest Journal of Nanomaterials & Biostructures (DJNB). 2021;16(2):585-592.
https://hdl.handle.net/21.15107/rcub_cherry_4936 .
Mandić, Boris, Simić, K., Trifunović, S., Vujisić, Ljubodrag V., Novaković, M., Tešević, Vele, Miljanić, O. Š., "Inhibition potency of disulphides and trisulphides on various tumor cell lines growth" in Digest Journal of Nanomaterials & Biostructures (DJNB), 16, no. 2 (2021):585-592,
https://hdl.handle.net/21.15107/rcub_cherry_4936 .

DNA protective activity of triterpenoids isolated from medicinal mushroom Fomitopsis betulina

Sofrenić, Ivana V.; Anđelković, Boban D.; Vujisić, Ljubodrag V.; Novaković, Miroslav M.; Knežević, Aleksandar; Stanković, Miroslava ; Milosavljević, Slobodan M.; Tešević, Vele

(Serbian Chemical Society, 2021)

TY  - JOUR
AU  - Sofrenić, Ivana V.
AU  - Anđelković, Boban D.
AU  - Vujisić, Ljubodrag V.
AU  - Novaković, Miroslav M.
AU  - Knežević, Aleksandar
AU  - Stanković, Miroslava

AU  - Milosavljević, Slobodan M.
AU  - Tešević, Vele
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4819
AB  - Eleven 31-methylenlanostane triterpenoids, i.e., seven 21- and four 26-oic acids, as well as a lupane triterpenoid betulin, isolated from the fruiting bodies of the mushroom Fomitopsis betulina, were tested for in vitro protective effect on chromosome aberrations in peripheral human lymphocytes using cytochalasin-B blocked micronucleus (CBMN) assay. Most of the tested compounds showed a beneficial effect by reducing DNA damage of human lymphocytes more effectively than amifostine, a radioprotective agent, used as a positive control. All the tested compounds decreased MN frequency in the concentration dependent manner, with the concentration of 2.0 µg mL-1 being the most effective – with increase of the concentration the activity slightly decreases. The structure–activity relationship (SAR) studies indicated that the lanostanes containing a conjugated 7,9 (11)-diene system exhibit lower activity than Δ8-analogues. It was also demonstrated that the DNA protective activities within the Δ8-lanostane-26-oic acid group are affected by the substitution in position 3 pattern. In the Δ8 series the oxygenation at C-12 or 16 as well as 21- or 26-oic acid functionality proved beneficial for in vitro protective effect on chromosomal aberrations. Betulin exhibited the lowest protective activity, but it is still comparable to that of amifostine.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - DNA protective activity of triterpenoids isolated from medicinal mushroom Fomitopsis betulina
VL  - 86
IS  - 9
SP  - 809
EP  - 817
DO  - 10.2298/JSC210401039S
ER  - 
@article{
author = "Sofrenić, Ivana V. and Anđelković, Boban D. and Vujisić, Ljubodrag V. and Novaković, Miroslav M. and Knežević, Aleksandar and Stanković, Miroslava
 and Milosavljević, Slobodan M. and Tešević, Vele",
year = "2021",
abstract = "Eleven 31-methylenlanostane triterpenoids, i.e., seven 21- and four 26-oic acids, as well as a lupane triterpenoid betulin, isolated from the fruiting bodies of the mushroom Fomitopsis betulina, were tested for in vitro protective effect on chromosome aberrations in peripheral human lymphocytes using cytochalasin-B blocked micronucleus (CBMN) assay. Most of the tested compounds showed a beneficial effect by reducing DNA damage of human lymphocytes more effectively than amifostine, a radioprotective agent, used as a positive control. All the tested compounds decreased MN frequency in the concentration dependent manner, with the concentration of 2.0 µg mL-1 being the most effective – with increase of the concentration the activity slightly decreases. The structure–activity relationship (SAR) studies indicated that the lanostanes containing a conjugated 7,9 (11)-diene system exhibit lower activity than Δ8-analogues. It was also demonstrated that the DNA protective activities within the Δ8-lanostane-26-oic acid group are affected by the substitution in position 3 pattern. In the Δ8 series the oxygenation at C-12 or 16 as well as 21- or 26-oic acid functionality proved beneficial for in vitro protective effect on chromosomal aberrations. Betulin exhibited the lowest protective activity, but it is still comparable to that of amifostine.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "DNA protective activity of triterpenoids isolated from medicinal mushroom Fomitopsis betulina",
volume = "86",
number = "9",
pages = "809-817",
doi = "10.2298/JSC210401039S"
}
Sofrenić, I. V., Anđelković, B. D., Vujisić, L. V., Novaković, M. M., Knežević, A., Stanković, M., Milosavljević, S. M.,& Tešević, V.. (2021). DNA protective activity of triterpenoids isolated from medicinal mushroom Fomitopsis betulina. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 86(9), 809-817.
https://doi.org/10.2298/JSC210401039S
Sofrenić IV, Anđelković BD, Vujisić LV, Novaković MM, Knežević A, Stanković M, Milosavljević SM, Tešević V. DNA protective activity of triterpenoids isolated from medicinal mushroom Fomitopsis betulina. in Journal of the Serbian Chemical Society. 2021;86(9):809-817.
doi:10.2298/JSC210401039S .
Sofrenić, Ivana V., Anđelković, Boban D., Vujisić, Ljubodrag V., Novaković, Miroslav M., Knežević, Aleksandar, Stanković, Miroslava
, Milosavljević, Slobodan M., Tešević, Vele, "DNA protective activity of triterpenoids isolated from medicinal mushroom Fomitopsis betulina" in Journal of the Serbian Chemical Society, 86, no. 9 (2021):809-817,
https://doi.org/10.2298/JSC210401039S . .

Cytotoxic triterpenoids and triterpene sugar esters from the medicinal mushroom Fomitopsis betulina

Sofrenić, Ivana V.; Anđelković, Boban D.; Todorović, Nina; Stanojković, Tatjana; Vujisić, Ljubodrag V.; Novaković, Miroslav M.; Milosavljević, Slobodan M.; Tešević, Vele

(2021)

TY  - JOUR
AU  - Sofrenić, Ivana V.
AU  - Anđelković, Boban D.
AU  - Todorović, Nina
AU  - Stanojković, Tatjana
AU  - Vujisić, Ljubodrag V.
AU  - Novaković, Miroslav M.
AU  - Milosavljević, Slobodan M.
AU  - Tešević, Vele
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4945
AB  - Thirteen undescribed 24-methylene lanostane triterpenoids, named polyporenic acids E-M and fomitosides L-O, as well as seventeen known analogues, were isolated from the fruiting bodies of the mushroom Fomitopsis betulina. Their structures were determined using 1D, 2D NMR, IR, and HRESIMS. Fomitoside L and fomitoside N exhibited cytotoxicity against HL60 leukemia cells (IC50 = 15.8 and 23.7 μM, respectively). Among the known compounds, notable cytotoxicities against HL60 leukemia cells and selectivity with respect to MRC-5 healthy cells were noticed for dehydropachymic acid (IC50 = 10.9 μM, SI 8.6), pachymic acid (IC50 = 11.0 μM, SI 9.8), 3-epi-dehydrotumulosic acid (IC50 = 19.9 μM, SI 5.8) and 12α-hydroxy-3α-(3′-hydroxy-4′-methoxycarbonyl-3′-methylbutyryloxy)-24-methyllanosta-8,24 (31)-dien-26-oic acid (IC50 = 19.2 μM, SI 2.2).
T2  - Phytochemistry
T1  - Cytotoxic triterpenoids and triterpene sugar esters from the medicinal mushroom Fomitopsis betulina
VL  - 181
SP  - 112580
DO  - 10.1016/j.phytochem.2020.112580
ER  - 
@article{
author = "Sofrenić, Ivana V. and Anđelković, Boban D. and Todorović, Nina and Stanojković, Tatjana and Vujisić, Ljubodrag V. and Novaković, Miroslav M. and Milosavljević, Slobodan M. and Tešević, Vele",
year = "2021",
abstract = "Thirteen undescribed 24-methylene lanostane triterpenoids, named polyporenic acids E-M and fomitosides L-O, as well as seventeen known analogues, were isolated from the fruiting bodies of the mushroom Fomitopsis betulina. Their structures were determined using 1D, 2D NMR, IR, and HRESIMS. Fomitoside L and fomitoside N exhibited cytotoxicity against HL60 leukemia cells (IC50 = 15.8 and 23.7 μM, respectively). Among the known compounds, notable cytotoxicities against HL60 leukemia cells and selectivity with respect to MRC-5 healthy cells were noticed for dehydropachymic acid (IC50 = 10.9 μM, SI 8.6), pachymic acid (IC50 = 11.0 μM, SI 9.8), 3-epi-dehydrotumulosic acid (IC50 = 19.9 μM, SI 5.8) and 12α-hydroxy-3α-(3′-hydroxy-4′-methoxycarbonyl-3′-methylbutyryloxy)-24-methyllanosta-8,24 (31)-dien-26-oic acid (IC50 = 19.2 μM, SI 2.2).",
journal = "Phytochemistry",
title = "Cytotoxic triterpenoids and triterpene sugar esters from the medicinal mushroom Fomitopsis betulina",
volume = "181",
pages = "112580",
doi = "10.1016/j.phytochem.2020.112580"
}
Sofrenić, I. V., Anđelković, B. D., Todorović, N., Stanojković, T., Vujisić, L. V., Novaković, M. M., Milosavljević, S. M.,& Tešević, V.. (2021). Cytotoxic triterpenoids and triterpene sugar esters from the medicinal mushroom Fomitopsis betulina. in Phytochemistry, 181, 112580.
https://doi.org/10.1016/j.phytochem.2020.112580
Sofrenić IV, Anđelković BD, Todorović N, Stanojković T, Vujisić LV, Novaković MM, Milosavljević SM, Tešević V. Cytotoxic triterpenoids and triterpene sugar esters from the medicinal mushroom Fomitopsis betulina. in Phytochemistry. 2021;181:112580.
doi:10.1016/j.phytochem.2020.112580 .
Sofrenić, Ivana V., Anđelković, Boban D., Todorović, Nina, Stanojković, Tatjana, Vujisić, Ljubodrag V., Novaković, Miroslav M., Milosavljević, Slobodan M., Tešević, Vele, "Cytotoxic triterpenoids and triterpene sugar esters from the medicinal mushroom Fomitopsis betulina" in Phytochemistry, 181 (2021):112580,
https://doi.org/10.1016/j.phytochem.2020.112580 . .
2
5
4
5

Supplementary data for the article: Sofrenić, I.; Anđelković, B.; Todorović, N.; Stanojković, T.; Vujisić, L.; Novaković, M.; Milosavljević, S.; Tešević, V. Cytotoxic Triterpenoids and Triterpene Sugar Esters from the Medicinal Mushroom Fomitopsis Betulina. Phytochemistry 2021, 181, 112580. https://doi.org/10.1016/j.phytochem.2020.112580.

Sofrenić, Ivana V.; Anđelković, Boban D.; Todorović, Nina; Stanojković, Tatjana; Vujisić, Ljubodrag V.; Novaković, Miroslav M.; Milosavljević, Slobodan M.; Tešević, Vele

(2021)

TY  - DATA
AU  - Sofrenić, Ivana V.
AU  - Anđelković, Boban D.
AU  - Todorović, Nina
AU  - Stanojković, Tatjana
AU  - Vujisić, Ljubodrag V.
AU  - Novaković, Miroslav M.
AU  - Milosavljević, Slobodan M.
AU  - Tešević, Vele
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4946
T2  - Phytochemistry
T1  - Supplementary data for the article: Sofrenić, I.; Anđelković, B.; Todorović, N.; Stanojković, T.; Vujisić, L.; Novaković, M.; Milosavljević, S.; Tešević, V. Cytotoxic Triterpenoids and Triterpene Sugar Esters from the Medicinal Mushroom Fomitopsis Betulina. Phytochemistry 2021, 181, 112580. https://doi.org/10.1016/j.phytochem.2020.112580.
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4946
ER  - 
@misc{
author = "Sofrenić, Ivana V. and Anđelković, Boban D. and Todorović, Nina and Stanojković, Tatjana and Vujisić, Ljubodrag V. and Novaković, Miroslav M. and Milosavljević, Slobodan M. and Tešević, Vele",
year = "2021",
journal = "Phytochemistry",
title = "Supplementary data for the article: Sofrenić, I.; Anđelković, B.; Todorović, N.; Stanojković, T.; Vujisić, L.; Novaković, M.; Milosavljević, S.; Tešević, V. Cytotoxic Triterpenoids and Triterpene Sugar Esters from the Medicinal Mushroom Fomitopsis Betulina. Phytochemistry 2021, 181, 112580. https://doi.org/10.1016/j.phytochem.2020.112580.",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4946"
}
Sofrenić, I. V., Anđelković, B. D., Todorović, N., Stanojković, T., Vujisić, L. V., Novaković, M. M., Milosavljević, S. M.,& Tešević, V.. (2021). Supplementary data for the article: Sofrenić, I.; Anđelković, B.; Todorović, N.; Stanojković, T.; Vujisić, L.; Novaković, M.; Milosavljević, S.; Tešević, V. Cytotoxic Triterpenoids and Triterpene Sugar Esters from the Medicinal Mushroom Fomitopsis Betulina. Phytochemistry 2021, 181, 112580. https://doi.org/10.1016/j.phytochem.2020.112580.. in Phytochemistry.
https://hdl.handle.net/21.15107/rcub_cherry_4946
Sofrenić IV, Anđelković BD, Todorović N, Stanojković T, Vujisić LV, Novaković MM, Milosavljević SM, Tešević V. Supplementary data for the article: Sofrenić, I.; Anđelković, B.; Todorović, N.; Stanojković, T.; Vujisić, L.; Novaković, M.; Milosavljević, S.; Tešević, V. Cytotoxic Triterpenoids and Triterpene Sugar Esters from the Medicinal Mushroom Fomitopsis Betulina. Phytochemistry 2021, 181, 112580. https://doi.org/10.1016/j.phytochem.2020.112580.. in Phytochemistry. 2021;.
https://hdl.handle.net/21.15107/rcub_cherry_4946 .
Sofrenić, Ivana V., Anđelković, Boban D., Todorović, Nina, Stanojković, Tatjana, Vujisić, Ljubodrag V., Novaković, Miroslav M., Milosavljević, Slobodan M., Tešević, Vele, "Supplementary data for the article: Sofrenić, I.; Anđelković, B.; Todorović, N.; Stanojković, T.; Vujisić, L.; Novaković, M.; Milosavljević, S.; Tešević, V. Cytotoxic Triterpenoids and Triterpene Sugar Esters from the Medicinal Mushroom Fomitopsis Betulina. Phytochemistry 2021, 181, 112580. https://doi.org/10.1016/j.phytochem.2020.112580." in Phytochemistry (2021),
https://hdl.handle.net/21.15107/rcub_cherry_4946 .

Screening of semi-volatile compounds in plants treated with coated cerium oxide nanoparticles by comprehensive two-dimensional gas chromatography

Milenković, Ivana; Radotić, Ksenija; Trifković, Jelena; Vujisić, Ljubodrag V.; Beškoski, Vladimir

(Wiley-VCH, 2021)

TY  - JOUR
AU  - Milenković, Ivana
AU  - Radotić, Ksenija
AU  - Trifković, Jelena
AU  - Vujisić, Ljubodrag V.
AU  - Beškoski, Vladimir
PY  - 2021
UR  - https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/jssc.202100145
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4519
AB  - Literature data about semi-volatile organic compounds in plants and the effect of cerium oxide nanoparticles on them are scarce. Surface modification of nanoparticles may change nanoparticle-environment interaction, and therefore affects compounds in plants. In this research, uncoated and glucose-, levan-, and pullulan-coated cerium oxide nanoparticles were used for wheat and pea treatment during the growth. The aim was the screening of semi-volatile organic compounds from plants’ shoots using comprehensive two-dimensional gas chromatography–mass spectrometry, a powerful separation technique allowing to reach unique separation resolution, and investigation of qualitative changes after the treatment with coated cerium oxide nanoparticles. The results were analyzed by the identification of individual peaks and fingerprint analysis by image processing. Wheat samples contained a higher number of semi-volatile organic compounds (108) compared to pea (77) but were less affected by the treatments with coated nanoparticles. The highest number of compounds was detected in wheat after the treatment with levan- and pullulan-coated nanoparticles, and in pea after treatment with levan-coated nanoparticles. This article reports a successful application of a semi-volatile organic compounds profile presented only as categorical variables and unique fingerprint images for the inter-cultivar recognition. This method may be useful in screening nanoparticles’ effects on different plants.
PB  - Wiley-VCH
T2  - Journal of Separation Science
T2  - Journal of Separation Science
T1  - Screening of semi-volatile compounds in plants treated with coated cerium oxide nanoparticles by comprehensive two-dimensional gas chromatography
VL  - 44
IS  - 11
SP  - 2260
EP  - 2268
DO  - 10.1002/jssc.202100145
ER  - 
@article{
author = "Milenković, Ivana and Radotić, Ksenija and Trifković, Jelena and Vujisić, Ljubodrag V. and Beškoski, Vladimir",
year = "2021",
abstract = "Literature data about semi-volatile organic compounds in plants and the effect of cerium oxide nanoparticles on them are scarce. Surface modification of nanoparticles may change nanoparticle-environment interaction, and therefore affects compounds in plants. In this research, uncoated and glucose-, levan-, and pullulan-coated cerium oxide nanoparticles were used for wheat and pea treatment during the growth. The aim was the screening of semi-volatile organic compounds from plants’ shoots using comprehensive two-dimensional gas chromatography–mass spectrometry, a powerful separation technique allowing to reach unique separation resolution, and investigation of qualitative changes after the treatment with coated cerium oxide nanoparticles. The results were analyzed by the identification of individual peaks and fingerprint analysis by image processing. Wheat samples contained a higher number of semi-volatile organic compounds (108) compared to pea (77) but were less affected by the treatments with coated nanoparticles. The highest number of compounds was detected in wheat after the treatment with levan- and pullulan-coated nanoparticles, and in pea after treatment with levan-coated nanoparticles. This article reports a successful application of a semi-volatile organic compounds profile presented only as categorical variables and unique fingerprint images for the inter-cultivar recognition. This method may be useful in screening nanoparticles’ effects on different plants.",
publisher = "Wiley-VCH",
journal = "Journal of Separation Science, Journal of Separation Science",
title = "Screening of semi-volatile compounds in plants treated with coated cerium oxide nanoparticles by comprehensive two-dimensional gas chromatography",
volume = "44",
number = "11",
pages = "2260-2268",
doi = "10.1002/jssc.202100145"
}
Milenković, I., Radotić, K., Trifković, J., Vujisić, L. V.,& Beškoski, V.. (2021). Screening of semi-volatile compounds in plants treated with coated cerium oxide nanoparticles by comprehensive two-dimensional gas chromatography. in Journal of Separation Science
Wiley-VCH., 44(11), 2260-2268.
https://doi.org/10.1002/jssc.202100145
Milenković I, Radotić K, Trifković J, Vujisić LV, Beškoski V. Screening of semi-volatile compounds in plants treated with coated cerium oxide nanoparticles by comprehensive two-dimensional gas chromatography. in Journal of Separation Science. 2021;44(11):2260-2268.
doi:10.1002/jssc.202100145 .
Milenković, Ivana, Radotić, Ksenija, Trifković, Jelena, Vujisić, Ljubodrag V., Beškoski, Vladimir, "Screening of semi-volatile compounds in plants treated with coated cerium oxide nanoparticles by comprehensive two-dimensional gas chromatography" in Journal of Separation Science, 44, no. 11 (2021):2260-2268,
https://doi.org/10.1002/jssc.202100145 . .
1
1
1
1

Supplementary data for the article: Milenković, I.; Radotić, K.; Trifković, J.; Vujisić, L.; Beškoski, V. P. Screening of Semi-Volatile Compounds in Plants Treated with Coated Cerium Oxide Nanoparticles by Comprehensive Two-Dimensional Gas Chromatography. Journal of Separation Science 2021, 44 (11), 2260–2268. https://doi.org/10.1002/jssc.202100145.

Milenković, Ivana; Radotić, Ksenija; Trifković, Jelena; Vujisić, Ljubodrag V.; Beškoski, Vladimir

(Wiley-VCH, 2021)

TY  - DATA
AU  - Milenković, Ivana
AU  - Radotić, Ksenija
AU  - Trifković, Jelena
AU  - Vujisić, Ljubodrag V.
AU  - Beškoski, Vladimir
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4520
PB  - Wiley-VCH
T2  - Journal of Separation Science
T1  - Supplementary data for the article: Milenković, I.; Radotić, K.; Trifković, J.; Vujisić, L.; Beškoski, V. P. Screening of Semi-Volatile Compounds in Plants Treated with Coated Cerium Oxide Nanoparticles by Comprehensive Two-Dimensional Gas Chromatography. Journal of Separation Science 2021, 44 (11), 2260–2268. https://doi.org/10.1002/jssc.202100145.
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4520
ER  - 
@misc{
author = "Milenković, Ivana and Radotić, Ksenija and Trifković, Jelena and Vujisić, Ljubodrag V. and Beškoski, Vladimir",
year = "2021",
publisher = "Wiley-VCH",
journal = "Journal of Separation Science",
title = "Supplementary data for the article: Milenković, I.; Radotić, K.; Trifković, J.; Vujisić, L.; Beškoski, V. P. Screening of Semi-Volatile Compounds in Plants Treated with Coated Cerium Oxide Nanoparticles by Comprehensive Two-Dimensional Gas Chromatography. Journal of Separation Science 2021, 44 (11), 2260–2268. https://doi.org/10.1002/jssc.202100145.",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4520"
}
Milenković, I., Radotić, K., Trifković, J., Vujisić, L. V.,& Beškoski, V.. (2021). Supplementary data for the article: Milenković, I.; Radotić, K.; Trifković, J.; Vujisić, L.; Beškoski, V. P. Screening of Semi-Volatile Compounds in Plants Treated with Coated Cerium Oxide Nanoparticles by Comprehensive Two-Dimensional Gas Chromatography. Journal of Separation Science 2021, 44 (11), 2260–2268. https://doi.org/10.1002/jssc.202100145.. in Journal of Separation Science
Wiley-VCH..
https://hdl.handle.net/21.15107/rcub_cherry_4520
Milenković I, Radotić K, Trifković J, Vujisić LV, Beškoski V. Supplementary data for the article: Milenković, I.; Radotić, K.; Trifković, J.; Vujisić, L.; Beškoski, V. P. Screening of Semi-Volatile Compounds in Plants Treated with Coated Cerium Oxide Nanoparticles by Comprehensive Two-Dimensional Gas Chromatography. Journal of Separation Science 2021, 44 (11), 2260–2268. https://doi.org/10.1002/jssc.202100145.. in Journal of Separation Science. 2021;.
https://hdl.handle.net/21.15107/rcub_cherry_4520 .
Milenković, Ivana, Radotić, Ksenija, Trifković, Jelena, Vujisić, Ljubodrag V., Beškoski, Vladimir, "Supplementary data for the article: Milenković, I.; Radotić, K.; Trifković, J.; Vujisić, L.; Beškoski, V. P. Screening of Semi-Volatile Compounds in Plants Treated with Coated Cerium Oxide Nanoparticles by Comprehensive Two-Dimensional Gas Chromatography. Journal of Separation Science 2021, 44 (11), 2260–2268. https://doi.org/10.1002/jssc.202100145." in Journal of Separation Science (2021),
https://hdl.handle.net/21.15107/rcub_cherry_4520 .

GC-FID-MS based metabolomics to access plum brandy quality

Ivanović, Stefan; Simić, Katarina; Tešević, Vele; Vujisić, Ljubodrag V.; Ljekočević, Marko; Gođevac, Dejan

(MDPI, 2021)

TY  - JOUR
AU  - Ivanović, Stefan
AU  - Simić, Katarina
AU  - Tešević, Vele
AU  - Vujisić, Ljubodrag V.
AU  - Ljekočević, Marko
AU  - Gođevac, Dejan
PY  - 2021
UR  - https://www.mdpi.com/1420-3049/26/5/1391
AB  - Plum brandy (Slivovitz (en); Šljivovica(sr)) is an alcoholic beverage that is increasingly consumed all over the world. Its quality assessment has become of great importance. In our study, the main volatiles and aroma compounds of 108 non-aged plum brandies originating from three plum cultivars, and fermented using different conditions, were investigated. The chemical profiles obtained after two-step GC-FID-MS analysis were subjected to multivariate data analysis to reveal the peculiarity in different cultivars and fermentation process. Correlation of plum brandy chemical composition with its sensory characteristics obtained by expert commission was also performed. The utilization of PCA and OPLS-DA multivariate analysis methods on GC-FID-MS, enabled discrimination of brandy samples based on differences in plum varieties, pH of plum mash, and addition of selected yeast or enzymes during fermentation. The correlation of brandy GC-FID-MS profiles with their sensory properties was achieved by OPLS multivariate analysis. Proposed workflow confirmed the potential of GC-FID-MS in combination with multivariate data analysis that can be applied to assess the plum brandy quality.
PB  - MDPI
T2  - Molecules
T2  - Molecules
T1  - GC-FID-MS based metabolomics to access plum brandy quality
VL  - 26
IS  - 5
SP  - 1391
DO  - 10.3390/molecules26051391
ER  - 
@article{
author = "Ivanović, Stefan and Simić, Katarina and Tešević, Vele and Vujisić, Ljubodrag V. and Ljekočević, Marko and Gođevac, Dejan",
year = "2021",
abstract = "Plum brandy (Slivovitz (en); Šljivovica(sr)) is an alcoholic beverage that is increasingly consumed all over the world. Its quality assessment has become of great importance. In our study, the main volatiles and aroma compounds of 108 non-aged plum brandies originating from three plum cultivars, and fermented using different conditions, were investigated. The chemical profiles obtained after two-step GC-FID-MS analysis were subjected to multivariate data analysis to reveal the peculiarity in different cultivars and fermentation process. Correlation of plum brandy chemical composition with its sensory characteristics obtained by expert commission was also performed. The utilization of PCA and OPLS-DA multivariate analysis methods on GC-FID-MS, enabled discrimination of brandy samples based on differences in plum varieties, pH of plum mash, and addition of selected yeast or enzymes during fermentation. The correlation of brandy GC-FID-MS profiles with their sensory properties was achieved by OPLS multivariate analysis. Proposed workflow confirmed the potential of GC-FID-MS in combination with multivariate data analysis that can be applied to assess the plum brandy quality.",
publisher = "MDPI",
journal = "Molecules, Molecules",
title = "GC-FID-MS based metabolomics to access plum brandy quality",
volume = "26",
number = "5",
pages = "1391",
doi = "10.3390/molecules26051391"
}
Ivanović, S., Simić, K., Tešević, V., Vujisić, L. V., Ljekočević, M.,& Gođevac, D.. (2021). GC-FID-MS based metabolomics to access plum brandy quality. in Molecules
MDPI., 26(5), 1391.
https://doi.org/10.3390/molecules26051391
Ivanović S, Simić K, Tešević V, Vujisić LV, Ljekočević M, Gođevac D. GC-FID-MS based metabolomics to access plum brandy quality. in Molecules. 2021;26(5):1391.
doi:10.3390/molecules26051391 .
Ivanović, Stefan, Simić, Katarina, Tešević, Vele, Vujisić, Ljubodrag V., Ljekočević, Marko, Gođevac, Dejan, "GC-FID-MS based metabolomics to access plum brandy quality" in Molecules, 26, no. 5 (2021):1391,
https://doi.org/10.3390/molecules26051391 . .
5
1
3

Supplementary data for the article: Ivanović, S.; Simić, K.; Tešević, V.; Vujisić, L.; Ljekočević, M.; Gođevac, D. GC-FID-MS Based Metabolomics to Access Plum Brandy Quality. Molecules 2021, 26 (5), 1391. https://doi.org/10.3390/molecules26051391.

Ivanović, Stefan; Simić, Katarina; Tešević, Vele; Vujisić, Ljubodrag V.; Ljekočević, Marko; Gođevac, Dejan

(MDPI, 2021)

TY  - DATA
AU  - Ivanović, Stefan
AU  - Simić, Katarina
AU  - Tešević, Vele
AU  - Vujisić, Ljubodrag V.
AU  - Ljekočević, Marko
AU  - Gođevac, Dejan
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4513
PB  - MDPI
T2  - Molecules
T1  - Supplementary data for the article: Ivanović, S.; Simić, K.; Tešević, V.; Vujisić, L.; Ljekočević, M.; Gođevac, D. GC-FID-MS Based Metabolomics to Access Plum Brandy Quality. Molecules 2021, 26 (5), 1391. https://doi.org/10.3390/molecules26051391.
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4514
ER  - 
@misc{
author = "Ivanović, Stefan and Simić, Katarina and Tešević, Vele and Vujisić, Ljubodrag V. and Ljekočević, Marko and Gođevac, Dejan",
year = "2021",
publisher = "MDPI",
journal = "Molecules",
title = "Supplementary data for the article: Ivanović, S.; Simić, K.; Tešević, V.; Vujisić, L.; Ljekočević, M.; Gođevac, D. GC-FID-MS Based Metabolomics to Access Plum Brandy Quality. Molecules 2021, 26 (5), 1391. https://doi.org/10.3390/molecules26051391.",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4514"
}
Ivanović, S., Simić, K., Tešević, V., Vujisić, L. V., Ljekočević, M.,& Gođevac, D.. (2021). Supplementary data for the article: Ivanović, S.; Simić, K.; Tešević, V.; Vujisić, L.; Ljekočević, M.; Gođevac, D. GC-FID-MS Based Metabolomics to Access Plum Brandy Quality. Molecules 2021, 26 (5), 1391. https://doi.org/10.3390/molecules26051391.. in Molecules
MDPI..
https://hdl.handle.net/21.15107/rcub_cherry_4514
Ivanović S, Simić K, Tešević V, Vujisić LV, Ljekočević M, Gođevac D. Supplementary data for the article: Ivanović, S.; Simić, K.; Tešević, V.; Vujisić, L.; Ljekočević, M.; Gođevac, D. GC-FID-MS Based Metabolomics to Access Plum Brandy Quality. Molecules 2021, 26 (5), 1391. https://doi.org/10.3390/molecules26051391.. in Molecules. 2021;.
https://hdl.handle.net/21.15107/rcub_cherry_4514 .
Ivanović, Stefan, Simić, Katarina, Tešević, Vele, Vujisić, Ljubodrag V., Ljekočević, Marko, Gođevac, Dejan, "Supplementary data for the article: Ivanović, S.; Simić, K.; Tešević, V.; Vujisić, L.; Ljekočević, M.; Gođevac, D. GC-FID-MS Based Metabolomics to Access Plum Brandy Quality. Molecules 2021, 26 (5), 1391. https://doi.org/10.3390/molecules26051391." in Molecules (2021),
https://hdl.handle.net/21.15107/rcub_cherry_4514 .

Pygidial glands of three ground beetle taxa (Insecta, Coleoptera, Carabidae): a study on their morphology and chemical composition of their secretions

Vranić, Sofija; Vesović, Nikola; Vujisić, Ljubodrag V.; Pavlović, Danica; Pantelić, Dejan; Todosijević, Marina; Ćurčić, Srećko

(Elsevier, 2021)

TY  - JOUR
AU  - Vranić, Sofija
AU  - Vesović, Nikola
AU  - Vujisić, Ljubodrag V.
AU  - Pavlović, Danica
AU  - Pantelić, Dejan
AU  - Todosijević, Marina
AU  - Ćurčić, Srećko
PY  - 2021
UR  - https://www.sciencedirect.com/science/article/pii/S0944200621000568
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4606
AB  - Morphology of the pygidial glands and chemical compositions of their secretion were analysed in the adults of three selected ground beetle taxa. Secretions of pygidial glands of Cychrus (Cychrus) semigranosus, Patrobus atrorufus and Pterostichus (Platysma) niger were chemically tested. Additionally, pygidial glands of the latter two species were investigated using bright-field microscopy and nonlinear microscopy and morphological features of the glands were described in detail. Both C. (C.) semigranosus and P. atrorufus were studied for the first time in terms of chemical ecology, while the latter species was analysed for the first time in terms of pygidial gland morphology. Altogether, eight compounds were detected in the dichloromethane extracts of the pygidial gland secretions of the three ground beetle taxa analysed. The simplest secretion mixtures were present in C. (C.) semigranosus and P. atrorufus (with two compounds each), while the extract of P. (P.) niger contained five compounds. The presence of 1-tetradecanol in the secretion of P. (P.) niger represents the first finding of this compound from the pygidial gland secretion extracts of ground beetles.
PB  - Elsevier
T2  - Zoology
T1  - Pygidial glands of three ground beetle taxa (Insecta, Coleoptera, Carabidae): a study on their morphology and chemical composition of their secretions
VL  - 148
SP  - 125948
DO  - 10.1016/j.zool.2021.125948
ER  - 
@article{
author = "Vranić, Sofija and Vesović, Nikola and Vujisić, Ljubodrag V. and Pavlović, Danica and Pantelić, Dejan and Todosijević, Marina and Ćurčić, Srećko",
year = "2021",
abstract = "Morphology of the pygidial glands and chemical compositions of their secretion were analysed in the adults of three selected ground beetle taxa. Secretions of pygidial glands of Cychrus (Cychrus) semigranosus, Patrobus atrorufus and Pterostichus (Platysma) niger were chemically tested. Additionally, pygidial glands of the latter two species were investigated using bright-field microscopy and nonlinear microscopy and morphological features of the glands were described in detail. Both C. (C.) semigranosus and P. atrorufus were studied for the first time in terms of chemical ecology, while the latter species was analysed for the first time in terms of pygidial gland morphology. Altogether, eight compounds were detected in the dichloromethane extracts of the pygidial gland secretions of the three ground beetle taxa analysed. The simplest secretion mixtures were present in C. (C.) semigranosus and P. atrorufus (with two compounds each), while the extract of P. (P.) niger contained five compounds. The presence of 1-tetradecanol in the secretion of P. (P.) niger represents the first finding of this compound from the pygidial gland secretion extracts of ground beetles.",
publisher = "Elsevier",
journal = "Zoology",
title = "Pygidial glands of three ground beetle taxa (Insecta, Coleoptera, Carabidae): a study on their morphology and chemical composition of their secretions",
volume = "148",
pages = "125948",
doi = "10.1016/j.zool.2021.125948"
}
Vranić, S., Vesović, N., Vujisić, L. V., Pavlović, D., Pantelić, D., Todosijević, M.,& Ćurčić, S.. (2021). Pygidial glands of three ground beetle taxa (Insecta, Coleoptera, Carabidae): a study on their morphology and chemical composition of their secretions. in Zoology
Elsevier., 148, 125948.
https://doi.org/10.1016/j.zool.2021.125948
Vranić S, Vesović N, Vujisić LV, Pavlović D, Pantelić D, Todosijević M, Ćurčić S. Pygidial glands of three ground beetle taxa (Insecta, Coleoptera, Carabidae): a study on their morphology and chemical composition of their secretions. in Zoology. 2021;148:125948.
doi:10.1016/j.zool.2021.125948 .
Vranić, Sofija, Vesović, Nikola, Vujisić, Ljubodrag V., Pavlović, Danica, Pantelić, Dejan, Todosijević, Marina, Ćurčić, Srećko, "Pygidial glands of three ground beetle taxa (Insecta, Coleoptera, Carabidae): a study on their morphology and chemical composition of their secretions" in Zoology, 148 (2021):125948,
https://doi.org/10.1016/j.zool.2021.125948 . .
2
1
1

Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae)

Vranić, Sofija; Ćurčić, Srećko; Vesović, Nikola; Mandić, Boris; Pantelić, Dejan; Vasović, Marija; Lazović, Vladimir; Zhang, Wang; Vujisić, Ljubodrag V.

(Elsevier, 2020)

TY  - JOUR
AU  - Vranić, Sofija
AU  - Ćurčić, Srećko
AU  - Vesović, Nikola
AU  - Mandić, Boris
AU  - Pantelić, Dejan
AU  - Vasović, Marija
AU  - Lazović, Vladimir
AU  - Zhang, Wang
AU  - Vujisić, Ljubodrag V.
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4240
AB  - Morphology of the pygidial glands and chemical composition of their secretions in adults of four ground beetle representatives of the Pterostichini tribe (Coleoptera: Carabidae) were analysed. Molops (Stenochoromus) montenegrinus, Pterostichus (Cophosus) cylindricus, P. (Feronidius) melas and P. (Pseudomaseus) nigrita were chemically tested, while the latter three species were morphologically investigated. Pterostichus (C.) cylindricus, P. (P.) nigrita and M. (S.) montenegrinus were chemically studied for the first time. Altogether, 23 chemical compounds were isolated using gas chromatography-mass spectrometry (GC-MS), of which some are new for Pterostichini or even Carabidae. Methacrylic acid was present in all species analysed. It was predominant in the secretion extract of P. (C.) cylindricus and P. (F.) melas. Isobutyric and 2-methylbutyric acids were the major components in the secretion of M. (S.) montenegrinus. Undecane, methacrylic and tiglic acids were the main components in the secretion of P. (P.) nigrita. The simplest chemical mixture was found in P. (C.) cylindricus (two compounds), while the most complex one was detected in P. (P.) nigrita (15 compounds). No significant differences in the chemical composition of the pygidial gland secretions were evidenced in P. (C.) cylindricus sampled from the same area and in the same season in two different years. Morphology of the pygidial glands of the studied species was analysed for the first time. Morphological features of the pygidial glands were observed using bright-field microscopy and nonlinear microscopy and described in details.
PB  - Elsevier
T2  - Zoology
T1  - Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae)
VL  - 142
SP  - 125772
DO  - 10.1016/j.zool.2020.125772
ER  - 
@article{
author = "Vranić, Sofija and Ćurčić, Srećko and Vesović, Nikola and Mandić, Boris and Pantelić, Dejan and Vasović, Marija and Lazović, Vladimir and Zhang, Wang and Vujisić, Ljubodrag V.",
year = "2020",
abstract = "Morphology of the pygidial glands and chemical composition of their secretions in adults of four ground beetle representatives of the Pterostichini tribe (Coleoptera: Carabidae) were analysed. Molops (Stenochoromus) montenegrinus, Pterostichus (Cophosus) cylindricus, P. (Feronidius) melas and P. (Pseudomaseus) nigrita were chemically tested, while the latter three species were morphologically investigated. Pterostichus (C.) cylindricus, P. (P.) nigrita and M. (S.) montenegrinus were chemically studied for the first time. Altogether, 23 chemical compounds were isolated using gas chromatography-mass spectrometry (GC-MS), of which some are new for Pterostichini or even Carabidae. Methacrylic acid was present in all species analysed. It was predominant in the secretion extract of P. (C.) cylindricus and P. (F.) melas. Isobutyric and 2-methylbutyric acids were the major components in the secretion of M. (S.) montenegrinus. Undecane, methacrylic and tiglic acids were the main components in the secretion of P. (P.) nigrita. The simplest chemical mixture was found in P. (C.) cylindricus (two compounds), while the most complex one was detected in P. (P.) nigrita (15 compounds). No significant differences in the chemical composition of the pygidial gland secretions were evidenced in P. (C.) cylindricus sampled from the same area and in the same season in two different years. Morphology of the pygidial glands of the studied species was analysed for the first time. Morphological features of the pygidial glands were observed using bright-field microscopy and nonlinear microscopy and described in details.",
publisher = "Elsevier",
journal = "Zoology",
title = "Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae)",
volume = "142",
pages = "125772",
doi = "10.1016/j.zool.2020.125772"
}
Vranić, S., Ćurčić, S., Vesović, N., Mandić, B., Pantelić, D., Vasović, M., Lazović, V., Zhang, W.,& Vujisić, L. V.. (2020). Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae). in Zoology
Elsevier., 142, 125772.
https://doi.org/10.1016/j.zool.2020.125772
Vranić S, Ćurčić S, Vesović N, Mandić B, Pantelić D, Vasović M, Lazović V, Zhang W, Vujisić LV. Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae). in Zoology. 2020;142:125772.
doi:10.1016/j.zool.2020.125772 .
Vranić, Sofija, Ćurčić, Srećko, Vesović, Nikola, Mandić, Boris, Pantelić, Dejan, Vasović, Marija, Lazović, Vladimir, Zhang, Wang, Vujisić, Ljubodrag V., "Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae)" in Zoology, 142 (2020):125772,
https://doi.org/10.1016/j.zool.2020.125772 . .
5
3
4

Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species

Vesović, Nikola; Ćurčić, Srećko; Todosijević, Marina; Nenadić, Marija; Zhang, Wang; Vujisić, Ljubodrag V.

(Springer, 2020)

TY  - JOUR
AU  - Vesović, Nikola
AU  - Ćurčić, Srećko
AU  - Todosijević, Marina
AU  - Nenadić, Marija
AU  - Zhang, Wang
AU  - Vujisić, Ljubodrag V.
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3972
AB  - It is a commonly known fact that all ground beetles possess abdominal pygidial glands with relatively similar gross structure and function among species. Still, morphology of the glands and composition of their secretions have not been studied in most ground beetle species. These exocrine glands and their products are mainly associated with defence in natural environments. In this paper, we studied three predatory ground beetle species of the genus Carabus Linnaeus, 1758, namely C. (Archicarabus) montivagus Palliardi, 1825, C. (Megodontus) caelatus Fabricius, 1801, and C. (M.) violaceus Linnaeus, 1758, to identify chemical components of their pygidial gland secretions. Altogether, 10 carboxylic acids were isolated from the analysed secretions [two from the secretion of C. (A.) montivagus, 10 from that of C. (M.) caelatus, and nine from that of C. (M.) violaceus]. The finding of 2-hexenoic acid in the secretion of C. (M.) caelatus is the first finding of it within the entire subfamily Carabinae. In addition, we also analysed the morphology of glands of the species C. (M.) violaceus.
PB  - Springer
T2  - Chemoecology
T1  - Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species
VL  - 30
IS  - 2
SP  - 59
EP  - 68
DO  - 10.1007/s00049-019-00298-w
ER  - 
@article{
author = "Vesović, Nikola and Ćurčić, Srećko and Todosijević, Marina and Nenadić, Marija and Zhang, Wang and Vujisić, Ljubodrag V.",
year = "2020",
abstract = "It is a commonly known fact that all ground beetles possess abdominal pygidial glands with relatively similar gross structure and function among species. Still, morphology of the glands and composition of their secretions have not been studied in most ground beetle species. These exocrine glands and their products are mainly associated with defence in natural environments. In this paper, we studied three predatory ground beetle species of the genus Carabus Linnaeus, 1758, namely C. (Archicarabus) montivagus Palliardi, 1825, C. (Megodontus) caelatus Fabricius, 1801, and C. (M.) violaceus Linnaeus, 1758, to identify chemical components of their pygidial gland secretions. Altogether, 10 carboxylic acids were isolated from the analysed secretions [two from the secretion of C. (A.) montivagus, 10 from that of C. (M.) caelatus, and nine from that of C. (M.) violaceus]. The finding of 2-hexenoic acid in the secretion of C. (M.) caelatus is the first finding of it within the entire subfamily Carabinae. In addition, we also analysed the morphology of glands of the species C. (M.) violaceus.",
publisher = "Springer",
journal = "Chemoecology",
title = "Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species",
volume = "30",
number = "2",
pages = "59-68",
doi = "10.1007/s00049-019-00298-w"
}
Vesović, N., Ćurčić, S., Todosijević, M., Nenadić, M., Zhang, W.,& Vujisić, L. V.. (2020). Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species. in Chemoecology
Springer., 30(2), 59-68.
https://doi.org/10.1007/s00049-019-00298-w
Vesović N, Ćurčić S, Todosijević M, Nenadić M, Zhang W, Vujisić LV. Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species. in Chemoecology. 2020;30(2):59-68.
doi:10.1007/s00049-019-00298-w .
Vesović, Nikola, Ćurčić, Srećko, Todosijević, Marina, Nenadić, Marija, Zhang, Wang, Vujisić, Ljubodrag V., "Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species" in Chemoecology, 30, no. 2 (2020):59-68,
https://doi.org/10.1007/s00049-019-00298-w . .
5
4
4

Jatrophane Diterpenoids With Protective Effect on Human Lymphocytes DNA

Krstić, Gordana B.; Jadranin, Milka; Stanković, Miroslava; Aljančić, Ivana; Vujisić, Ljubodrag V.; Mandić, Boris; Tešević, Vele

(SAGE Journals, 2019)

TY  - JOUR
AU  - Krstić, Gordana B.
AU  - Jadranin, Milka
AU  - Stanković, Miroslava
AU  - Aljančić, Ivana
AU  - Vujisić, Ljubodrag V.
AU  - Mandić, Boris
AU  - Tešević, Vele
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3143
AB  - Two sets of structurally different jatrophanes (1-11 and 13-16), jatrophane 12, and latex extract of 2 Euphorbia species (17 and 18) were tested for in vitro protective effect against chromosome aberrations in peripheral human lymphocytes using the cytokinesis-block micronucleus (CBMN) assay. Jatrophanes 1-6 in minimal doses of 1 µg/mL prominently decreased micronuclei (MN) frequency in the range 44.86% to 34.29% and manifested considerable protective effect. From the other set of jatrophanes, 13 in the same minimal dose notably decreased MN frequency by 31.05%, while extracts 17 and 18 at a concentration of 4 µg/mL remarkably decreased the frequency of MN by 37.94% and 36.12%, respectively. Jatrophanes 12, 14, and 16 showed moderate protection, while 7-11 and 15 were less active than positive control. The structure-activity relationship (SAR) studies of the tested jatrophanes (1-16) indicated the favorable position of benzoate at C-8 or C-9 (3, 4, and 13) and a preference of isobutanoyloxy group at C-3 (1-3) rather than propanoyloxy at the same position (4-6) for pronounced protective effect on human lymphocytes DNA. In a previous SAR study on 11 jatrophanes (1, 3-8, and 13-16), the same structural features in 3, 4, and 13 influenced powerful inhibition of P-gp, while growth inhibition of cancer cells was more than doubled in 1 (isobutanoyloxy group at C-3) compared to 6 (propanoyloxy at C-3).
PB  - SAGE Journals
T2  - Natural Product Communications
T1  - Jatrophane Diterpenoids With Protective Effect on Human Lymphocytes DNA
VL  - 14
IS  - 5
DO  - 10.1177/1934578X19848168
ER  - 
@article{
author = "Krstić, Gordana B. and Jadranin, Milka and Stanković, Miroslava and Aljančić, Ivana and Vujisić, Ljubodrag V. and Mandić, Boris and Tešević, Vele",
year = "2019",
abstract = "Two sets of structurally different jatrophanes (1-11 and 13-16), jatrophane 12, and latex extract of 2 Euphorbia species (17 and 18) were tested for in vitro protective effect against chromosome aberrations in peripheral human lymphocytes using the cytokinesis-block micronucleus (CBMN) assay. Jatrophanes 1-6 in minimal doses of 1 µg/mL prominently decreased micronuclei (MN) frequency in the range 44.86% to 34.29% and manifested considerable protective effect. From the other set of jatrophanes, 13 in the same minimal dose notably decreased MN frequency by 31.05%, while extracts 17 and 18 at a concentration of 4 µg/mL remarkably decreased the frequency of MN by 37.94% and 36.12%, respectively. Jatrophanes 12, 14, and 16 showed moderate protection, while 7-11 and 15 were less active than positive control. The structure-activity relationship (SAR) studies of the tested jatrophanes (1-16) indicated the favorable position of benzoate at C-8 or C-9 (3, 4, and 13) and a preference of isobutanoyloxy group at C-3 (1-3) rather than propanoyloxy at the same position (4-6) for pronounced protective effect on human lymphocytes DNA. In a previous SAR study on 11 jatrophanes (1, 3-8, and 13-16), the same structural features in 3, 4, and 13 influenced powerful inhibition of P-gp, while growth inhibition of cancer cells was more than doubled in 1 (isobutanoyloxy group at C-3) compared to 6 (propanoyloxy at C-3).",
publisher = "SAGE Journals",
journal = "Natural Product Communications",
title = "Jatrophane Diterpenoids With Protective Effect on Human Lymphocytes DNA",
volume = "14",
number = "5",
doi = "10.1177/1934578X19848168"
}
Krstić, G. B., Jadranin, M., Stanković, M., Aljančić, I., Vujisić, L. V., Mandić, B.,& Tešević, V.. (2019). Jatrophane Diterpenoids With Protective Effect on Human Lymphocytes DNA. in Natural Product Communications
SAGE Journals., 14(5).
https://doi.org/10.1177/1934578X19848168
Krstić GB, Jadranin M, Stanković M, Aljančić I, Vujisić LV, Mandić B, Tešević V. Jatrophane Diterpenoids With Protective Effect on Human Lymphocytes DNA. in Natural Product Communications. 2019;14(5).
doi:10.1177/1934578X19848168 .
Krstić, Gordana B., Jadranin, Milka, Stanković, Miroslava, Aljančić, Ivana, Vujisić, Ljubodrag V., Mandić, Boris, Tešević, Vele, "Jatrophane Diterpenoids With Protective Effect on Human Lymphocytes DNA" in Natural Product Communications, 14, no. 5 (2019),
https://doi.org/10.1177/1934578X19848168 . .
4
4
5

Leaf-surface guaianolides from Amphoricarpos neumaeyri showing protective effect on human lymphocytes DNA

Cvetković, Mirjana; Đorđević, Iris; Jadranin, Milka; Stanković, Miroslava; Mandić, Boris; Milosavljević, Slobodan M.; Vujisić, Ljubodrag V.

(Informa UK Limited, 2019)

TY  - JOUR
AU  - Cvetković, Mirjana
AU  - Đorđević, Iris
AU  - Jadranin, Milka
AU  - Stanković, Miroslava
AU  - Mandić, Boris
AU  - Milosavljević, Slobodan M.
AU  - Vujisić, Ljubodrag V.
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4938
AB  - Analysis of composition of CH2Cl2 surface extract of leaves of Amphoricarpos neumayeri Vis. revealed 16 sesquiterpene lactones with guaianolide skeleton, so called amphoricarpolides, typical for this genus. Four of them, 13–16, were new derivatives and their structures were elucidated by detailed analyses of IR, NMR and MS data. Amphoricarpolide (9), its 15-O-acetyl derivative (5), and two 9β-hydroxyamphoricarpolides, 3,15-di-O-acetyl- and 3-O-acetyl-15-O-isovaleroyl derivatives (3 and 6, respectively) were tested for in vitro protective effect on chromosome aberrations in peripheral human lymphocytes using cytochalasin-B blocked micronucleus (CBMN) assay. The tested compound exerted a beneficial effect by decreasing DNA damage of human lymphocytes.
PB  - Informa UK Limited
T2  - Natural Product Research
T1  - Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA
SP  - 1
EP  - 9
DO  - 10.1080/14786419.2019.1687470
ER  - 
@article{
author = "Cvetković, Mirjana and Đorđević, Iris and Jadranin, Milka and Stanković, Miroslava and Mandić, Boris and Milosavljević, Slobodan M. and Vujisić, Ljubodrag V.",
year = "2019",
abstract = "Analysis of composition of CH2Cl2 surface extract of leaves of Amphoricarpos neumayeri Vis. revealed 16 sesquiterpene lactones with guaianolide skeleton, so called amphoricarpolides, typical for this genus. Four of them, 13–16, were new derivatives and their structures were elucidated by detailed analyses of IR, NMR and MS data. Amphoricarpolide (9), its 15-O-acetyl derivative (5), and two 9β-hydroxyamphoricarpolides, 3,15-di-O-acetyl- and 3-O-acetyl-15-O-isovaleroyl derivatives (3 and 6, respectively) were tested for in vitro protective effect on chromosome aberrations in peripheral human lymphocytes using cytochalasin-B blocked micronucleus (CBMN) assay. The tested compound exerted a beneficial effect by decreasing DNA damage of human lymphocytes.",
publisher = "Informa UK Limited",
journal = "Natural Product Research",
title = "Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA",
pages = "1-9",
doi = "10.1080/14786419.2019.1687470"
}
Cvetković, M., Đorđević, I., Jadranin, M., Stanković, M., Mandić, B., Milosavljević, S. M.,& Vujisić, L. V.. (2019). Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA. in Natural Product Research
Informa UK Limited., 1-9.
https://doi.org/10.1080/14786419.2019.1687470
Cvetković M, Đorđević I, Jadranin M, Stanković M, Mandić B, Milosavljević SM, Vujisić LV. Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA. in Natural Product Research. 2019;:1-9.
doi:10.1080/14786419.2019.1687470 .
Cvetković, Mirjana, Đorđević, Iris, Jadranin, Milka, Stanković, Miroslava, Mandić, Boris, Milosavljević, Slobodan M., Vujisić, Ljubodrag V., "Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA" in Natural Product Research (2019):1-9,
https://doi.org/10.1080/14786419.2019.1687470 . .
1
3

Essential oil profile in relation to geographic origin and plant organ of Satureja kitaibelii Wierzb. ex Heuff.

Dodoš, Tanja; Rajčević, Nemanja; Janaćković, Peđa T.; Vujisić, Ljubodrag V.; Marin, Petar D.

(Elsevier, 2019)

TY  - JOUR
AU  - Dodoš, Tanja
AU  - Rajčević, Nemanja
AU  - Janaćković, Peđa T.
AU  - Vujisić, Ljubodrag V.
AU  - Marin, Petar D.
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3296
AB  - Satureja kitaibelii is an endemic aromatic herb used in ethnomedicine for treatment of bronchitis or cough, urinary and digestive disorders, but also as a stimulant, stomachic, carminative, expectorant, anti-catarrhal, astringent and aphrodisiac. Recent investigations also show potential anticancer activity. The aim of this study was to investigate the effects of the geographic origin and the plant organs (leaves and flowers) on the essential oil profile of S. kitaibelii. Forty-five individuals from three populations were studied, and their individual essential oils (EOs) were extracted using simultaneous distillation and extraction (SDE) and analysed using gas chromatography coupled to mass spectrometry. The essential oil composition is characterised by the domination of monoterpenes (52.5–84.9%), followed by sesquiterpenes (10.9–36.0%). Analyses showed that EO profile varied considerably from one location to another. The dominant component in population Djerdap was p-cymene (21.9%), while linalool (22.2%) and p-cymene (16.9%) dominated EO of individuals from population Poganovo. Also, in the latter population, two chemotypes were observed. Population Temšica EO profile was characterized by the presence of several co-dominant components with similar content (between 5 and 12%). Highest EO variability was observed in population Poganovo, while the lowest was in population Temšica. The essential oil profiles showed differentiation between populations in agreement with the spatial distribution. To better assess the contribution of each plant part in essential oil profile, individual parts (leaves, calyx, and corolla) and whole aerial parts of the plant were analysed from a random individual. Results showed differences between EO profiles of plant parts and whole plant (herba). Furthermore, the chemical composition of herba depends on the quantity of each plant part (leaves, calyces and corollas). Profile of essential oil also varied within the plant. Sesquiterpenes dominated the essential oil from flower parts, while monoterpenes dominated in the essential oil of leaves and aerial parts of the plant.
PB  - Elsevier
T2  - Industrial Crops and Products
T1  - Essential oil profile in relation to geographic origin and plant organ of Satureja kitaibelii Wierzb. ex Heuff.
VL  - 139
DO  - 10.1016/j.indcrop.2019.111549
ER  - 
@article{
author = "Dodoš, Tanja and Rajčević, Nemanja and Janaćković, Peđa T. and Vujisić, Ljubodrag V. and Marin, Petar D.",
year = "2019",
abstract = "Satureja kitaibelii is an endemic aromatic herb used in ethnomedicine for treatment of bronchitis or cough, urinary and digestive disorders, but also as a stimulant, stomachic, carminative, expectorant, anti-catarrhal, astringent and aphrodisiac. Recent investigations also show potential anticancer activity. The aim of this study was to investigate the effects of the geographic origin and the plant organs (leaves and flowers) on the essential oil profile of S. kitaibelii. Forty-five individuals from three populations were studied, and their individual essential oils (EOs) were extracted using simultaneous distillation and extraction (SDE) and analysed using gas chromatography coupled to mass spectrometry. The essential oil composition is characterised by the domination of monoterpenes (52.5–84.9%), followed by sesquiterpenes (10.9–36.0%). Analyses showed that EO profile varied considerably from one location to another. The dominant component in population Djerdap was p-cymene (21.9%), while linalool (22.2%) and p-cymene (16.9%) dominated EO of individuals from population Poganovo. Also, in the latter population, two chemotypes were observed. Population Temšica EO profile was characterized by the presence of several co-dominant components with similar content (between 5 and 12%). Highest EO variability was observed in population Poganovo, while the lowest was in population Temšica. The essential oil profiles showed differentiation between populations in agreement with the spatial distribution. To better assess the contribution of each plant part in essential oil profile, individual parts (leaves, calyx, and corolla) and whole aerial parts of the plant were analysed from a random individual. Results showed differences between EO profiles of plant parts and whole plant (herba). Furthermore, the chemical composition of herba depends on the quantity of each plant part (leaves, calyces and corollas). Profile of essential oil also varied within the plant. Sesquiterpenes dominated the essential oil from flower parts, while monoterpenes dominated in the essential oil of leaves and aerial parts of the plant.",
publisher = "Elsevier",
journal = "Industrial Crops and Products",
title = "Essential oil profile in relation to geographic origin and plant organ of Satureja kitaibelii Wierzb. ex Heuff.",
volume = "139",
doi = "10.1016/j.indcrop.2019.111549"
}
Dodoš, T., Rajčević, N., Janaćković, P. T., Vujisić, L. V.,& Marin, P. D.. (2019). Essential oil profile in relation to geographic origin and plant organ of Satureja kitaibelii Wierzb. ex Heuff.. in Industrial Crops and Products
Elsevier., 139.
https://doi.org/10.1016/j.indcrop.2019.111549
Dodoš T, Rajčević N, Janaćković PT, Vujisić LV, Marin PD. Essential oil profile in relation to geographic origin and plant organ of Satureja kitaibelii Wierzb. ex Heuff.. in Industrial Crops and Products. 2019;139.
doi:10.1016/j.indcrop.2019.111549 .
Dodoš, Tanja, Rajčević, Nemanja, Janaćković, Peđa T., Vujisić, Ljubodrag V., Marin, Petar D., "Essential oil profile in relation to geographic origin and plant organ of Satureja kitaibelii Wierzb. ex Heuff." in Industrial Crops and Products, 139 (2019),
https://doi.org/10.1016/j.indcrop.2019.111549 . .
2
12
7
10

Supplementary material for the article: Dodoš, T.; Rajčević, N.; Janaćković, P.; Vujisić, L.; Marin, P. D. Essential Oil Profile in Relation to Geographic Origin and Plant Organ of Satureja Kitaibelii Wierzb. Ex Heuff. Industrial Crops and Products 2019, 139. https://doi.org/10.1016/j.indcrop.2019.111549

Dodoš, Tanja; Rajčević, Nemanja; Janaćković, Peđa T.; Vujisić, Ljubodrag V.; Marin, Petar D.

(Elsevier, 2019)

TY  - DATA
AU  - Dodoš, Tanja
AU  - Rajčević, Nemanja
AU  - Janaćković, Peđa T.
AU  - Vujisić, Ljubodrag V.
AU  - Marin, Petar D.
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3297
PB  - Elsevier
T2  - Industrial Crops and Products
T1  - Supplementary material for the article: Dodoš, T.; Rajčević, N.; Janaćković, P.; Vujisić, L.; Marin, P. D. Essential Oil Profile in Relation to Geographic Origin and Plant Organ of Satureja Kitaibelii Wierzb. Ex Heuff. Industrial Crops and Products 2019, 139. https://doi.org/10.1016/j.indcrop.2019.111549
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3297
ER  - 
@misc{
author = "Dodoš, Tanja and Rajčević, Nemanja and Janaćković, Peđa T. and Vujisić, Ljubodrag V. and Marin, Petar D.",
year = "2019",
publisher = "Elsevier",
journal = "Industrial Crops and Products",
title = "Supplementary material for the article: Dodoš, T.; Rajčević, N.; Janaćković, P.; Vujisić, L.; Marin, P. D. Essential Oil Profile in Relation to Geographic Origin and Plant Organ of Satureja Kitaibelii Wierzb. Ex Heuff. Industrial Crops and Products 2019, 139. https://doi.org/10.1016/j.indcrop.2019.111549",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3297"
}
Dodoš, T., Rajčević, N., Janaćković, P. T., Vujisić, L. V.,& Marin, P. D.. (2019). Supplementary material for the article: Dodoš, T.; Rajčević, N.; Janaćković, P.; Vujisić, L.; Marin, P. D. Essential Oil Profile in Relation to Geographic Origin and Plant Organ of Satureja Kitaibelii Wierzb. Ex Heuff. Industrial Crops and Products 2019, 139. https://doi.org/10.1016/j.indcrop.2019.111549. in Industrial Crops and Products
Elsevier..
https://hdl.handle.net/21.15107/rcub_cherry_3297
Dodoš T, Rajčević N, Janaćković PT, Vujisić LV, Marin PD. Supplementary material for the article: Dodoš, T.; Rajčević, N.; Janaćković, P.; Vujisić, L.; Marin, P. D. Essential Oil Profile in Relation to Geographic Origin and Plant Organ of Satureja Kitaibelii Wierzb. Ex Heuff. Industrial Crops and Products 2019, 139. https://doi.org/10.1016/j.indcrop.2019.111549. in Industrial Crops and Products. 2019;.
https://hdl.handle.net/21.15107/rcub_cherry_3297 .
Dodoš, Tanja, Rajčević, Nemanja, Janaćković, Peđa T., Vujisić, Ljubodrag V., Marin, Petar D., "Supplementary material for the article: Dodoš, T.; Rajčević, N.; Janaćković, P.; Vujisić, L.; Marin, P. D. Essential Oil Profile in Relation to Geographic Origin and Plant Organ of Satureja Kitaibelii Wierzb. Ex Heuff. Industrial Crops and Products 2019, 139. https://doi.org/10.1016/j.indcrop.2019.111549" in Industrial Crops and Products (2019),
https://hdl.handle.net/21.15107/rcub_cherry_3297 .

Millipedes vs. pathogens: Defensive secretions of some julids (Diplopoda: Julida) as potential antimicrobial agents

Ilic, Bojan; Dimkić, Ivica; Unković, Nikola; Ljaljević-Grbić, Milica; Vukojević, Jelena; Vujisić, Ljubodrag V.; Tešević, Vele; Stanković, Slaviša; Makarov, Slobodan E.; Lučić, Luka

(Wiley, Hoboken, 2018)

TY  - JOUR
AU  - Ilic, Bojan
AU  - Dimkić, Ivica
AU  - Unković, Nikola
AU  - Ljaljević-Grbić, Milica
AU  - Vukojević, Jelena
AU  - Vujisić, Ljubodrag V.
AU  - Tešević, Vele
AU  - Stanković, Slaviša
AU  - Makarov, Slobodan E.
AU  - Lučić, Luka
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2198
AB  - In the light of growing interest in discovering new sources of natural antimicrobial agents, we extracted and tested the efficiency of julid defensive secretions in comparison with commercially used antibiotic and antimycotics. This work involved chemical characterization of the defensive secretions of Cylindroiulus boleti (C. L. Koch, 1847), Megaphyllum bosniense (Verhoeff, 1897) and M.unilineatum (C. L. Koch, 1838), as well as in vitro evaluation of their antimicrobial activity against 11 bacteria, one yeast and eight filamentous fungi. Compounds of the analysed defensive secretions included p-benzoquinones, alkyl esters of fatty acids and ketones. Ketones were recorded for the first time in the order Julida, and they were detected in secretions of both Megaphyllum species. All three analysed defensive secretions showed antibacterial and antifungal potential against all of the tested pathogens. Staphylococcus aureus proved to be the most sensitive bacterial strain to all analysed secretions. Also, defensive secretion of M.unilineatum showed significant antibacterial potential against Bacillus subtilis. The most resistant bacterial strains in this study were Escherichia coli, Erwinia persicina and Pseudomonas syringae pv. tomato. Analysed defensive secretions achieved the strongest antifungal activity against Aspergillus parasiticus (secretions of all three millipede species), Penicillium griseofulvum (secretions of C.boleti and M.bosniense) and Cladosporium oxysporum (secretion of M.unilineatum). The most resistant mycromycetes were A.niger (to all tested defensive secretions), A.flavus (to secretion of M.unilineatum) and P.lanosum (to secretions of C.boleti and M.bosniense). Our results showed a generally lower level of activity compared to antibiotic and a significantly higher level compared to antimycotics. The results of this study elucidate and open opportunities for further research in the field of millipede chemical ecology.
PB  - Wiley, Hoboken
T2  - Journal of Applied Entomology
T1  - Millipedes vs. pathogens: Defensive secretions of some julids (Diplopoda: Julida) as potential antimicrobial agents
VL  - 142
IS  - 8
SP  - 775
EP  - 791
DO  - 10.1111/jen.12526
UR  - Kon_3529
ER  - 
@article{
author = "Ilic, Bojan and Dimkić, Ivica and Unković, Nikola and Ljaljević-Grbić, Milica and Vukojević, Jelena and Vujisić, Ljubodrag V. and Tešević, Vele and Stanković, Slaviša and Makarov, Slobodan E. and Lučić, Luka",
year = "2018",
abstract = "In the light of growing interest in discovering new sources of natural antimicrobial agents, we extracted and tested the efficiency of julid defensive secretions in comparison with commercially used antibiotic and antimycotics. This work involved chemical characterization of the defensive secretions of Cylindroiulus boleti (C. L. Koch, 1847), Megaphyllum bosniense (Verhoeff, 1897) and M.unilineatum (C. L. Koch, 1838), as well as in vitro evaluation of their antimicrobial activity against 11 bacteria, one yeast and eight filamentous fungi. Compounds of the analysed defensive secretions included p-benzoquinones, alkyl esters of fatty acids and ketones. Ketones were recorded for the first time in the order Julida, and they were detected in secretions of both Megaphyllum species. All three analysed defensive secretions showed antibacterial and antifungal potential against all of the tested pathogens. Staphylococcus aureus proved to be the most sensitive bacterial strain to all analysed secretions. Also, defensive secretion of M.unilineatum showed significant antibacterial potential against Bacillus subtilis. The most resistant bacterial strains in this study were Escherichia coli, Erwinia persicina and Pseudomonas syringae pv. tomato. Analysed defensive secretions achieved the strongest antifungal activity against Aspergillus parasiticus (secretions of all three millipede species), Penicillium griseofulvum (secretions of C.boleti and M.bosniense) and Cladosporium oxysporum (secretion of M.unilineatum). The most resistant mycromycetes were A.niger (to all tested defensive secretions), A.flavus (to secretion of M.unilineatum) and P.lanosum (to secretions of C.boleti and M.bosniense). Our results showed a generally lower level of activity compared to antibiotic and a significantly higher level compared to antimycotics. The results of this study elucidate and open opportunities for further research in the field of millipede chemical ecology.",
publisher = "Wiley, Hoboken",
journal = "Journal of Applied Entomology",
title = "Millipedes vs. pathogens: Defensive secretions of some julids (Diplopoda: Julida) as potential antimicrobial agents",
volume = "142",
number = "8",
pages = "775-791",
doi = "10.1111/jen.12526",
url = "Kon_3529"
}
Ilic, B., Dimkić, I., Unković, N., Ljaljević-Grbić, M., Vukojević, J., Vujisić, L. V., Tešević, V., Stanković, S., Makarov, S. E.,& Lučić, L.. (2018). Millipedes vs. pathogens: Defensive secretions of some julids (Diplopoda: Julida) as potential antimicrobial agents. in Journal of Applied Entomology
Wiley, Hoboken., 142(8), 775-791.
https://doi.org/10.1111/jen.12526
Kon_3529
Ilic B, Dimkić I, Unković N, Ljaljević-Grbić M, Vukojević J, Vujisić LV, Tešević V, Stanković S, Makarov SE, Lučić L. Millipedes vs. pathogens: Defensive secretions of some julids (Diplopoda: Julida) as potential antimicrobial agents. in Journal of Applied Entomology. 2018;142(8):775-791.
doi:10.1111/jen.12526
Kon_3529 .
Ilic, Bojan, Dimkić, Ivica, Unković, Nikola, Ljaljević-Grbić, Milica, Vukojević, Jelena, Vujisić, Ljubodrag V., Tešević, Vele, Stanković, Slaviša, Makarov, Slobodan E., Lučić, Luka, "Millipedes vs. pathogens: Defensive secretions of some julids (Diplopoda: Julida) as potential antimicrobial agents" in Journal of Applied Entomology, 142, no. 8 (2018):775-791,
https://doi.org/10.1111/jen.12526 .,
Kon_3529 .
4
4
4

Supplementary material for the article: Ilić, B.; Dimkić, I.; Unković, N.; Grbić, M. L.; Vukojević, J.; Vujisić, L.; Tešević, V.; Stanković, S.; Makarov, S.; Lučić, L. Millipedes vs. Pathogens: Defensive Secretions of Some Julids (Diplopoda: Julida) as Potential Antimicrobial Agents. Journal of Applied Entomology 2018, 142 (8), 775–791. https://doi.org/10.1111/jen.12526

Ilic, Bojan; Dimkić, Ivica; Unković, Nikola; Ljaljević-Grbić, Milica; Vukojević, Jelena; Vujisić, Ljubodrag V.; Tešević, Vele; Stanković, Slaviša; Makarov, Slobodan E.; Lučić, Luka

(Wiley, Hoboken, 2018)

TY  - DATA
AU  - Ilic, Bojan
AU  - Dimkić, Ivica
AU  - Unković, Nikola
AU  - Ljaljević-Grbić, Milica
AU  - Vukojević, Jelena
AU  - Vujisić, Ljubodrag V.
AU  - Tešević, Vele
AU  - Stanković, Slaviša
AU  - Makarov, Slobodan E.
AU  - Lučić, Luka
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3238
PB  - Wiley, Hoboken
T2  - Journal of Applied Entomology
T1  - Supplementary material for the article: Ilić, B.; Dimkić, I.; Unković, N.; Grbić, M. L.; Vukojević, J.; Vujisić, L.; Tešević, V.; Stanković, S.; Makarov, S.; Lučić, L. Millipedes vs. Pathogens: Defensive Secretions of Some Julids (Diplopoda: Julida) as Potential Antimicrobial Agents. Journal of Applied Entomology 2018, 142 (8), 775–791. https://doi.org/10.1111/jen.12526
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3238
ER  - 
@misc{
author = "Ilic, Bojan and Dimkić, Ivica and Unković, Nikola and Ljaljević-Grbić, Milica and Vukojević, Jelena and Vujisić, Ljubodrag V. and Tešević, Vele and Stanković, Slaviša and Makarov, Slobodan E. and Lučić, Luka",
year = "2018",
publisher = "Wiley, Hoboken",
journal = "Journal of Applied Entomology",
title = "Supplementary material for the article: Ilić, B.; Dimkić, I.; Unković, N.; Grbić, M. L.; Vukojević, J.; Vujisić, L.; Tešević, V.; Stanković, S.; Makarov, S.; Lučić, L. Millipedes vs. Pathogens: Defensive Secretions of Some Julids (Diplopoda: Julida) as Potential Antimicrobial Agents. Journal of Applied Entomology 2018, 142 (8), 775–791. https://doi.org/10.1111/jen.12526",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3238"
}
Ilic, B., Dimkić, I., Unković, N., Ljaljević-Grbić, M., Vukojević, J., Vujisić, L. V., Tešević, V., Stanković, S., Makarov, S. E.,& Lučić, L.. (2018). Supplementary material for the article: Ilić, B.; Dimkić, I.; Unković, N.; Grbić, M. L.; Vukojević, J.; Vujisić, L.; Tešević, V.; Stanković, S.; Makarov, S.; Lučić, L. Millipedes vs. Pathogens: Defensive Secretions of Some Julids (Diplopoda: Julida) as Potential Antimicrobial Agents. Journal of Applied Entomology 2018, 142 (8), 775–791. https://doi.org/10.1111/jen.12526. in Journal of Applied Entomology
Wiley, Hoboken..
https://hdl.handle.net/21.15107/rcub_cherry_3238
Ilic B, Dimkić I, Unković N, Ljaljević-Grbić M, Vukojević J, Vujisić LV, Tešević V, Stanković S, Makarov SE, Lučić L. Supplementary material for the article: Ilić, B.; Dimkić, I.; Unković, N.; Grbić, M. L.; Vukojević, J.; Vujisić, L.; Tešević, V.; Stanković, S.; Makarov, S.; Lučić, L. Millipedes vs. Pathogens: Defensive Secretions of Some Julids (Diplopoda: Julida) as Potential Antimicrobial Agents. Journal of Applied Entomology 2018, 142 (8), 775–791. https://doi.org/10.1111/jen.12526. in Journal of Applied Entomology. 2018;.
https://hdl.handle.net/21.15107/rcub_cherry_3238 .
Ilic, Bojan, Dimkić, Ivica, Unković, Nikola, Ljaljević-Grbić, Milica, Vukojević, Jelena, Vujisić, Ljubodrag V., Tešević, Vele, Stanković, Slaviša, Makarov, Slobodan E., Lučić, Luka, "Supplementary material for the article: Ilić, B.; Dimkić, I.; Unković, N.; Grbić, M. L.; Vukojević, J.; Vujisić, L.; Tešević, V.; Stanković, S.; Makarov, S.; Lučić, L. Millipedes vs. Pathogens: Defensive Secretions of Some Julids (Diplopoda: Julida) as Potential Antimicrobial Agents. Journal of Applied Entomology 2018, 142 (8), 775–791. https://doi.org/10.1111/jen.12526" in Journal of Applied Entomology (2018),
https://hdl.handle.net/21.15107/rcub_cherry_3238 .

Short communication: Cheese supplemented with Thymus algeriensis oil, a potential natural food preservative

Bukvicki, Danka; Giweli, Abdulhmid; Stojković, Dejan; Vujisić, Ljubodrag V.; Tešević, Vele; Nikolić, Miloš; Soković, Marina; Marin, Petar D.

(Elsevier Science Inc, New York, 2018)

TY  - JOUR
AU  - Bukvicki, Danka
AU  - Giweli, Abdulhmid
AU  - Stojković, Dejan
AU  - Vujisić, Ljubodrag V.
AU  - Tešević, Vele
AU  - Nikolić, Miloš
AU  - Soković, Marina
AU  - Marin, Petar D.
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2140
AB  - The essential oil of Thymus algeriensis was analyzed as a potential preservative in soft cheese. We developed a novel method to test the preserving properties of essential oil in soft cheese. Contamination incidence of Penicillium aurantiogriseum was absent after 30 d of storage at 4 degrees C with 25 mu L of essential oil added. The antimicrobial activity was tested against 8 bacteria and 8 fungi. Thymus algeriensis oil showed inhibitory activity against tested bacteria at 0.03 to 0.09 mg/mL, and bactericidal activity was achieved at 0.05 to 0.15 mg/mL. For antifungal activity, minimum inhibitory concentrations ranged between 0.01 and 0.04 mg/mL and minimum fungicidal concentrations between 0.01 and 0.04 mg/mL. Furthermore, the oil was also screened for antiradical activity using the 1,1-diphenyl-2-picrylhydrazyl assay. The results showed that the oil was active and achieved half-maximal inhibitory activity at 0.132 mg/mL. We used gas chromatography, gas chromatography-mass spectrometry, and nuclear magnetic resonance spectrometry to investigate the volatile compounds from the oil. Carvacrol was identified as the main compound in the oil, represented by 80.9% of the total constituents, followed by p-cymene (7.7%).
PB  - Elsevier Science Inc, New York
T2  - Journal of Dairy Science
T1  - Short communication: Cheese supplemented with Thymus algeriensis oil, a potential natural food preservative
VL  - 101
IS  - 5
SP  - 3859
EP  - 3865
DO  - 10.3168/jds.2017-13714
UR  - Kon_3471
ER  - 
@article{
author = "Bukvicki, Danka and Giweli, Abdulhmid and Stojković, Dejan and Vujisić, Ljubodrag V. and Tešević, Vele and Nikolić, Miloš and Soković, Marina and Marin, Petar D.",
year = "2018",
abstract = "The essential oil of Thymus algeriensis was analyzed as a potential preservative in soft cheese. We developed a novel method to test the preserving properties of essential oil in soft cheese. Contamination incidence of Penicillium aurantiogriseum was absent after 30 d of storage at 4 degrees C with 25 mu L of essential oil added. The antimicrobial activity was tested against 8 bacteria and 8 fungi. Thymus algeriensis oil showed inhibitory activity against tested bacteria at 0.03 to 0.09 mg/mL, and bactericidal activity was achieved at 0.05 to 0.15 mg/mL. For antifungal activity, minimum inhibitory concentrations ranged between 0.01 and 0.04 mg/mL and minimum fungicidal concentrations between 0.01 and 0.04 mg/mL. Furthermore, the oil was also screened for antiradical activity using the 1,1-diphenyl-2-picrylhydrazyl assay. The results showed that the oil was active and achieved half-maximal inhibitory activity at 0.132 mg/mL. We used gas chromatography, gas chromatography-mass spectrometry, and nuclear magnetic resonance spectrometry to investigate the volatile compounds from the oil. Carvacrol was identified as the main compound in the oil, represented by 80.9% of the total constituents, followed by p-cymene (7.7%).",
publisher = "Elsevier Science Inc, New York",
journal = "Journal of Dairy Science",
title = "Short communication: Cheese supplemented with Thymus algeriensis oil, a potential natural food preservative",
volume = "101",
number = "5",
pages = "3859-3865",
doi = "10.3168/jds.2017-13714",
url = "Kon_3471"
}
Bukvicki, D., Giweli, A., Stojković, D., Vujisić, L. V., Tešević, V., Nikolić, M., Soković, M.,& Marin, P. D.. (2018). Short communication: Cheese supplemented with Thymus algeriensis oil, a potential natural food preservative. in Journal of Dairy Science
Elsevier Science Inc, New York., 101(5), 3859-3865.
https://doi.org/10.3168/jds.2017-13714
Kon_3471
Bukvicki D, Giweli A, Stojković D, Vujisić LV, Tešević V, Nikolić M, Soković M, Marin PD. Short communication: Cheese supplemented with Thymus algeriensis oil, a potential natural food preservative. in Journal of Dairy Science. 2018;101(5):3859-3865.
doi:10.3168/jds.2017-13714
Kon_3471 .
Bukvicki, Danka, Giweli, Abdulhmid, Stojković, Dejan, Vujisić, Ljubodrag V., Tešević, Vele, Nikolić, Miloš, Soković, Marina, Marin, Petar D., "Short communication: Cheese supplemented with Thymus algeriensis oil, a potential natural food preservative" in Journal of Dairy Science, 101, no. 5 (2018):3859-3865,
https://doi.org/10.3168/jds.2017-13714 .,
Kon_3471 .
1
15
11
16

NMR Spectroscopy in the Analysis of Illegal Drugs

Vajs, Vlatka; Đorđević, Iris; Vujisić, Ljubodrag V.; Milosavljević, Slobodan M.

(2018)

TY  - CHAP
AU  - Vajs, Vlatka
AU  - Đorđević, Iris
AU  - Vujisić, Ljubodrag V.
AU  - Milosavljević, Slobodan M.
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2841
AB  - The detection of illegal drugs in various samples has been among the most fascinating objects for the practicing analytical chemist involved in forensic analysis. For centuries (until the end of the nineteenth century), drugs were almost entirely of natural origin, mostly herbal, and in some cases slightly chemically modified (e.g., through acetylation of morphine to heroin). By the development of synthetic organic chemistry (commencing at the beginning of the twentieth century), quite a few synthetic drugs designed to mimic the pharmacological effects of drugs originating from natural sources have been designed (e.g., cannabimimetic indazole derivatives or amphetamines, etc.). Detection of such synthetic drugs, named “designer drugs,” due to a large number of new substances continuously emerging on the market, is crucial. The efficacy of this analysis has become a tremendous challenge in the analytical forensic field. A development of fast identification and structural characterization is greatly facilitated by the advent of modern spectroscopic techniques, namely nuclear magnetic resonance spectroscopy (NMR) and modern mass spectrometry (MS) as well as separation techniques, such as gas and liquid chromatography (GC and LC). Nowadays, rapid strategies for chemical characterizations of illicit drugs are available.
T2  - Chromatographic Techniques in the Forensic Analysis of Designer Drugs
T1  - NMR Spectroscopy in the Analysis of Illegal Drugs
SP  - 177
EP  - 197
DO  - 10.1201/9781315313177
ER  - 
@inbook{
author = "Vajs, Vlatka and Đorđević, Iris and Vujisić, Ljubodrag V. and Milosavljević, Slobodan M.",
year = "2018",
abstract = "The detection of illegal drugs in various samples has been among the most fascinating objects for the practicing analytical chemist involved in forensic analysis. For centuries (until the end of the nineteenth century), drugs were almost entirely of natural origin, mostly herbal, and in some cases slightly chemically modified (e.g., through acetylation of morphine to heroin). By the development of synthetic organic chemistry (commencing at the beginning of the twentieth century), quite a few synthetic drugs designed to mimic the pharmacological effects of drugs originating from natural sources have been designed (e.g., cannabimimetic indazole derivatives or amphetamines, etc.). Detection of such synthetic drugs, named “designer drugs,” due to a large number of new substances continuously emerging on the market, is crucial. The efficacy of this analysis has become a tremendous challenge in the analytical forensic field. A development of fast identification and structural characterization is greatly facilitated by the advent of modern spectroscopic techniques, namely nuclear magnetic resonance spectroscopy (NMR) and modern mass spectrometry (MS) as well as separation techniques, such as gas and liquid chromatography (GC and LC). Nowadays, rapid strategies for chemical characterizations of illicit drugs are available.",
journal = "Chromatographic Techniques in the Forensic Analysis of Designer Drugs",
booktitle = "NMR Spectroscopy in the Analysis of Illegal Drugs",
pages = "177-197",
doi = "10.1201/9781315313177"
}
Vajs, V., Đorđević, I., Vujisić, L. V.,& Milosavljević, S. M.. (2018). NMR Spectroscopy in the Analysis of Illegal Drugs. in Chromatographic Techniques in the Forensic Analysis of Designer Drugs, 177-197.
https://doi.org/10.1201/9781315313177
Vajs V, Đorđević I, Vujisić LV, Milosavljević SM. NMR Spectroscopy in the Analysis of Illegal Drugs. in Chromatographic Techniques in the Forensic Analysis of Designer Drugs. 2018;:177-197.
doi:10.1201/9781315313177 .
Vajs, Vlatka, Đorđević, Iris, Vujisić, Ljubodrag V., Milosavljević, Slobodan M., "NMR Spectroscopy in the Analysis of Illegal Drugs" in Chromatographic Techniques in the Forensic Analysis of Designer Drugs (2018):177-197,
https://doi.org/10.1201/9781315313177 . .
4

Supplementary data for the article: Ljaljević Grbić, M.; Unković, N.; Dimkić, I.; Janaćković, P.; Gavrilović, M.; Stanojević, O.; Stupar, M.; Vujisić, L.; Jelikić, A.; Stanković, S.; et al. Frankincense and Myrrh Essential Oils and Burn Incense Fume against Micro-Inhabitants of Sacral Ambients. Wisdom of the Ancients? Journal of Ethnopharmacology 2018, 219, 1–14. https://doi.org/10.1016/j.jep.2018.03.003

Ljaljević-Grbić, Milica; Unković, Nikola; Dimkić, Ivica; Janaćković, Peđa T.; Gavrilović, Milan; Stanojević, Olja; Stupar, Miloš; Vujisić, Ljubodrag V.; Jelikić, Aleksa; Stanković, Slaviša; Vukojević, Jelena

(Elsevier Ireland Ltd, Clare, 2018)

TY  - DATA
AU  - Ljaljević-Grbić, Milica
AU  - Unković, Nikola
AU  - Dimkić, Ivica
AU  - Janaćković, Peđa T.
AU  - Gavrilović, Milan
AU  - Stanojević, Olja
AU  - Stupar, Miloš
AU  - Vujisić, Ljubodrag V.
AU  - Jelikić, Aleksa
AU  - Stanković, Slaviša
AU  - Vukojević, Jelena
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2931
PB  - Elsevier Ireland Ltd, Clare
T2  - Journal of Ethnopharmacology
T1  - Supplementary data for the article: Ljaljević Grbić, M.; Unković, N.; Dimkić, I.; Janaćković, P.; Gavrilović, M.; Stanojević, O.; Stupar, M.; Vujisić, L.; Jelikić, A.; Stanković, S.; et al. Frankincense and Myrrh Essential Oils and Burn Incense Fume against Micro-Inhabitants of Sacral Ambients. Wisdom of the Ancients? Journal of Ethnopharmacology 2018, 219, 1–14. https://doi.org/10.1016/j.jep.2018.03.003
UR  - https://hdl.handle.net/21.15107/rcub_cherry_2931
ER  - 
@misc{
author = "Ljaljević-Grbić, Milica and Unković, Nikola and Dimkić, Ivica and Janaćković, Peđa T. and Gavrilović, Milan and Stanojević, Olja and Stupar, Miloš and Vujisić, Ljubodrag V. and Jelikić, Aleksa and Stanković, Slaviša and Vukojević, Jelena",
year = "2018",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Journal of Ethnopharmacology",
title = "Supplementary data for the article: Ljaljević Grbić, M.; Unković, N.; Dimkić, I.; Janaćković, P.; Gavrilović, M.; Stanojević, O.; Stupar, M.; Vujisić, L.; Jelikić, A.; Stanković, S.; et al. Frankincense and Myrrh Essential Oils and Burn Incense Fume against Micro-Inhabitants of Sacral Ambients. Wisdom of the Ancients? Journal of Ethnopharmacology 2018, 219, 1–14. https://doi.org/10.1016/j.jep.2018.03.003",
url = "https://hdl.handle.net/21.15107/rcub_cherry_2931"
}
Ljaljević-Grbić, M., Unković, N., Dimkić, I., Janaćković, P. T., Gavrilović, M., Stanojević, O., Stupar, M., Vujisić, L. V., Jelikić, A., Stanković, S.,& Vukojević, J.. (2018). Supplementary data for the article: Ljaljević Grbić, M.; Unković, N.; Dimkić, I.; Janaćković, P.; Gavrilović, M.; Stanojević, O.; Stupar, M.; Vujisić, L.; Jelikić, A.; Stanković, S.; et al. Frankincense and Myrrh Essential Oils and Burn Incense Fume against Micro-Inhabitants of Sacral Ambients. Wisdom of the Ancients? Journal of Ethnopharmacology 2018, 219, 1–14. https://doi.org/10.1016/j.jep.2018.03.003. in Journal of Ethnopharmacology
Elsevier Ireland Ltd, Clare..
https://hdl.handle.net/21.15107/rcub_cherry_2931
Ljaljević-Grbić M, Unković N, Dimkić I, Janaćković PT, Gavrilović M, Stanojević O, Stupar M, Vujisić LV, Jelikić A, Stanković S, Vukojević J. Supplementary data for the article: Ljaljević Grbić, M.; Unković, N.; Dimkić, I.; Janaćković, P.; Gavrilović, M.; Stanojević, O.; Stupar, M.; Vujisić, L.; Jelikić, A.; Stanković, S.; et al. Frankincense and Myrrh Essential Oils and Burn Incense Fume against Micro-Inhabitants of Sacral Ambients. Wisdom of the Ancients? Journal of Ethnopharmacology 2018, 219, 1–14. https://doi.org/10.1016/j.jep.2018.03.003. in Journal of Ethnopharmacology. 2018;.
https://hdl.handle.net/21.15107/rcub_cherry_2931 .
Ljaljević-Grbić, Milica, Unković, Nikola, Dimkić, Ivica, Janaćković, Peđa T., Gavrilović, Milan, Stanojević, Olja, Stupar, Miloš, Vujisić, Ljubodrag V., Jelikić, Aleksa, Stanković, Slaviša, Vukojević, Jelena, "Supplementary data for the article: Ljaljević Grbić, M.; Unković, N.; Dimkić, I.; Janaćković, P.; Gavrilović, M.; Stanojević, O.; Stupar, M.; Vujisić, L.; Jelikić, A.; Stanković, S.; et al. Frankincense and Myrrh Essential Oils and Burn Incense Fume against Micro-Inhabitants of Sacral Ambients. Wisdom of the Ancients? Journal of Ethnopharmacology 2018, 219, 1–14. https://doi.org/10.1016/j.jep.2018.03.003" in Journal of Ethnopharmacology (2018),
https://hdl.handle.net/21.15107/rcub_cherry_2931 .

Frankincense and myrrh essential oils and burn incense fume against micro-inhabitants of sacral ambients. Wisdom of the ancients?

Ljaljević-Grbić, Milica; Unković, Nikola; Dimkić, Ivica; Janaćković, Peđa T.; Gavrilović, Milan; Stanojević, Olja; Stupar, Miloš; Vujisić, Ljubodrag V.; Jelikić, Aleksa; Stanković, Slaviša; Vukojević, Jelena

(Elsevier Ireland Ltd, Clare, 2018)

TY  - JOUR
AU  - Ljaljević-Grbić, Milica
AU  - Unković, Nikola
AU  - Dimkić, Ivica
AU  - Janaćković, Peđa T.
AU  - Gavrilović, Milan
AU  - Stanojević, Olja
AU  - Stupar, Miloš
AU  - Vujisić, Ljubodrag V.
AU  - Jelikić, Aleksa
AU  - Stanković, Slaviša
AU  - Vukojević, Jelena
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2158
AB  - Ethnopharmacological relevance: Essential oils obtained from resins of Boswellia carteri Birdw. and Commiphora myrrha (Nees) Engl., commonly known as frankincense and true myrrh respectively, have been used extensively since 2800 BCE for the treatment of skin sores, wounds, teeth, inflammation, and urinary tract diseases in traditional medicine; for preparation of mummification balms and unguents; and also as incense and perfumes. Since ancient times, burning of frankincense and myrrh in places of worship for spiritual purposes and contemplation (a ubiquitous practice across various religions) had hygienic functions, to refine the smell and reduce contagion by purifying the indoor air. Aim of the study: The general purpose of the study was to assess the in vitro antimicrobial potential of the liquid and vapour phases of B. carteri and C. myrrha essential oils and burn incense, as well as to test the effectiveness of their in situ application to cleanse microbially-contaminated air within the ambient of an investigated 17th century church. Materials and methods: The chemical composition of B. carteri and C. myrrha essential oils, obtained by hydro distillation of frankincense and true myrrh oleo gum resins was determined using GC/MS, and antimicrobial properties of their liquid and vapour phases were assessed by the broth microdilution and microatmosphere diffusion methods. Chemical analysis of burn incense fume obtained using bottle gas washing with dichloromethane as a solvent was performed by GC/MS, while its antimicrobial activity was evaluated using a modified microatmosphere diffusion method to evaluate germination inhibition for fungi and CFU count reduction for bacteria. The in situ antimicrobial activity of B. carteri burn incense and essential oil vapour phase was assessed in the sealed nave and diaconicon of the church, respectively. Results: The dominant compounds of B. carteri EO were a-pinene (38.41%) and myrcene (15.21%), while C. myrrha EO was characterized by high content of furanoeudesma-1,3-diene (17.65%), followed by curzerene (12.97%), f3-elemene (12.70%), and germacrene B (12.15%). Burn incense fume and soot had a-pinene (68.6%) and incensole (28.6%) as the most dominant compounds, respectively. In vitro antimicrobial assays demonstrated high bacterial and fungal sensitivity to the liquid and vapour phases of Eos, and burn incense fume. In situ application of B. carteri EO vapour and incense fume resulted in reduction of air -borne viable microbial counts by up to 45.39 +/- 2.83% for fungi and 67.56 +/- 3.12% for bacteria (EO); and by up to 80.43 +/- 2.07% for fungi and 91.43 +/- 1.26% for bacteria (incense fume). Conclusions: The antimicrobial properties of essential oil derived from frankincense, a compound with wellknown traditional use, showed that it possesses a clear potential as a natural antimicrobial agent. Moreover, the results suggest possible application of B. carteri EO vapour and incense fume as occasional air purifiers in sacral ambients, apart from daily church rituals.
PB  - Elsevier Ireland Ltd, Clare
T2  - Journal of Ethnopharmacology
T1  - Frankincense and myrrh essential oils and burn incense fume against micro-inhabitants of sacral ambients. Wisdom of the ancients?
VL  - 219
SP  - 1
EP  - 14
DO  - 10.1016/j.jep.2018.03.003
UR  - Kon_3489
ER  - 
@article{
author = "Ljaljević-Grbić, Milica and Unković, Nikola and Dimkić, Ivica and Janaćković, Peđa T. and Gavrilović, Milan and Stanojević, Olja and Stupar, Miloš and Vujisić, Ljubodrag V. and Jelikić, Aleksa and Stanković, Slaviša and Vukojević, Jelena",
year = "2018",
abstract = "Ethnopharmacological relevance: Essential oils obtained from resins of Boswellia carteri Birdw. and Commiphora myrrha (Nees) Engl., commonly known as frankincense and true myrrh respectively, have been used extensively since 2800 BCE for the treatment of skin sores, wounds, teeth, inflammation, and urinary tract diseases in traditional medicine; for preparation of mummification balms and unguents; and also as incense and perfumes. Since ancient times, burning of frankincense and myrrh in places of worship for spiritual purposes and contemplation (a ubiquitous practice across various religions) had hygienic functions, to refine the smell and reduce contagion by purifying the indoor air. Aim of the study: The general purpose of the study was to assess the in vitro antimicrobial potential of the liquid and vapour phases of B. carteri and C. myrrha essential oils and burn incense, as well as to test the effectiveness of their in situ application to cleanse microbially-contaminated air within the ambient of an investigated 17th century church. Materials and methods: The chemical composition of B. carteri and C. myrrha essential oils, obtained by hydro distillation of frankincense and true myrrh oleo gum resins was determined using GC/MS, and antimicrobial properties of their liquid and vapour phases were assessed by the broth microdilution and microatmosphere diffusion methods. Chemical analysis of burn incense fume obtained using bottle gas washing with dichloromethane as a solvent was performed by GC/MS, while its antimicrobial activity was evaluated using a modified microatmosphere diffusion method to evaluate germination inhibition for fungi and CFU count reduction for bacteria. The in situ antimicrobial activity of B. carteri burn incense and essential oil vapour phase was assessed in the sealed nave and diaconicon of the church, respectively. Results: The dominant compounds of B. carteri EO were a-pinene (38.41%) and myrcene (15.21%), while C. myrrha EO was characterized by high content of furanoeudesma-1,3-diene (17.65%), followed by curzerene (12.97%), f3-elemene (12.70%), and germacrene B (12.15%). Burn incense fume and soot had a-pinene (68.6%) and incensole (28.6%) as the most dominant compounds, respectively. In vitro antimicrobial assays demonstrated high bacterial and fungal sensitivity to the liquid and vapour phases of Eos, and burn incense fume. In situ application of B. carteri EO vapour and incense fume resulted in reduction of air -borne viable microbial counts by up to 45.39 +/- 2.83% for fungi and 67.56 +/- 3.12% for bacteria (EO); and by up to 80.43 +/- 2.07% for fungi and 91.43 +/- 1.26% for bacteria (incense fume). Conclusions: The antimicrobial properties of essential oil derived from frankincense, a compound with wellknown traditional use, showed that it possesses a clear potential as a natural antimicrobial agent. Moreover, the results suggest possible application of B. carteri EO vapour and incense fume as occasional air purifiers in sacral ambients, apart from daily church rituals.",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Journal of Ethnopharmacology",
title = "Frankincense and myrrh essential oils and burn incense fume against micro-inhabitants of sacral ambients. Wisdom of the ancients?",
volume = "219",
pages = "1-14",
doi = "10.1016/j.jep.2018.03.003",
url = "Kon_3489"
}
Ljaljević-Grbić, M., Unković, N., Dimkić, I., Janaćković, P. T., Gavrilović, M., Stanojević, O., Stupar, M., Vujisić, L. V., Jelikić, A., Stanković, S.,& Vukojević, J.. (2018). Frankincense and myrrh essential oils and burn incense fume against micro-inhabitants of sacral ambients. Wisdom of the ancients?. in Journal of Ethnopharmacology
Elsevier Ireland Ltd, Clare., 219, 1-14.
https://doi.org/10.1016/j.jep.2018.03.003
Kon_3489
Ljaljević-Grbić M, Unković N, Dimkić I, Janaćković PT, Gavrilović M, Stanojević O, Stupar M, Vujisić LV, Jelikić A, Stanković S, Vukojević J. Frankincense and myrrh essential oils and burn incense fume against micro-inhabitants of sacral ambients. Wisdom of the ancients?. in Journal of Ethnopharmacology. 2018;219:1-14.
doi:10.1016/j.jep.2018.03.003
Kon_3489 .
Ljaljević-Grbić, Milica, Unković, Nikola, Dimkić, Ivica, Janaćković, Peđa T., Gavrilović, Milan, Stanojević, Olja, Stupar, Miloš, Vujisić, Ljubodrag V., Jelikić, Aleksa, Stanković, Slaviša, Vukojević, Jelena, "Frankincense and myrrh essential oils and burn incense fume against micro-inhabitants of sacral ambients. Wisdom of the ancients?" in Journal of Ethnopharmacology, 219 (2018):1-14,
https://doi.org/10.1016/j.jep.2018.03.003 .,
Kon_3489 .
35
20
19
20

Enzymatic lipophilization of vitamin C with linoleic acid: Determination of antioxidant and diffusion properties of L-ascorbyl linoleate

Ćorović, Marija; Milivojević, Ana; Carević, Milica B.; Banjanac, Katarina; Vujisić, Ljubodrag V.; Pjanović, Rada V.; Bezbradica, Dejan

(2018)

TY  - JOUR
AU  - Ćorović, Marija
AU  - Milivojević, Ana
AU  - Carević, Milica B.
AU  - Banjanac, Katarina
AU  - Vujisić, Ljubodrag V.
AU  - Pjanović, Rada V.
AU  - Bezbradica, Dejan
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/217
AB  - Lipophilic derivatives of vitamin C are additives with antioxidant properties, attractive for application in food, cosmetics and pharmaceutics. They could be synthesized in lipase-catalyzed processes by using various acyl donors. Hereby, we present application of linoleic acid, which is polyunsaturated fatty acid essential in human nutrition, for esterification of vitamin C catalyzed by immobilized enzyme preparation Novozym® 435 in acetone. Highest specific ester yield, 9.7 mmol/g of immobilized lipase, was accomplished with 0.15 M of vitamin C, 0.6 M of linoleic acid, 3 g/l of enzyme and 0.07% (v/v) of water, at 60°C. NMR analyses of purified product proved that synthesized molecule was identical to 6-O-ascorbyl linoleate. Capacity of ester for scavenging 2,2-diphenyl-1-picrylhydrazyl radicals was two times higher comparing to parent molecule, vitamin C. Its diffusion coefficient, determined using Franz cell and cellulose acetate membrane, was 40% higher than palmitate and 62% higher than oleate. Obtained results showed that L-ascorbyl linoleate could be successfully synthesized in biocatalyzed processes. Furthermore, it was demonstrated that it possess high potential for application in different lipophilic products due to its liposolubility, high antioxidant efficiency and good diffusion properties.
AB  - Lipofilni derivati vitamina C su aditivi sa antioksidativnim dejstvom pogodni za primenu u prehrambenim, kozmetičkim i farmaceutskim proizvodima. Mogu biti sintetisani u procesima katalizovanim lipazama korišćenjem različitih acil-donora. U ovom radu, opisana je primena linolne kiseline, polinezasićene masne kiseline esencijalne u ljudskoj ishrani, u esterifikaciji vitamina C katalizovanoj imobilisanim enzimskim preparatom Novozym® 435 u acetonu. Najviši specifični prinos estra od 9,7 mmol/g imobilisane lipaze, ostvaren je sa 0,15 M vitamina C, 0,6 M linolne kiseline, 3 g/l enzima i 0,07 zapr. % vode, na 60°C. NMR analize prečišćenog proizvoda dokazale su da je sintetisani molekul identičan 6-O-askorbil-linolatu. Kapacitet estra za vezivanje 2,2- difenil-1-pikrilhidrazil radikala bio je dva puta viši u odnosu na sam vitamin C. Njegov koeficijent difuzije, određen korišćenjem Franz-ove ćelije i celuloza-acetatne membrane, bio je za 40% viši u odnosu na palmitat i za 62% u odnosu na oleat. Ostvareni rezultati pokazali su da L-askorbil-linolat može uspešno biti sintetisan u biokatalizovanom procesu. Pored toga, dokazano je da ovaj estar poseduje značajan potencijal za primenu u različitim lipofilnim proizvodima zbog svoje liposolubilnosti, snažnog antioksidativnog dejstva i pogodnih difuzionih karakteristika.
T2  - Food and Feed Research
T1  - Enzymatic lipophilization of vitamin C with linoleic acid: Determination of antioxidant and diffusion properties of L-ascorbyl linoleate
T1  - enzimska lipofilizacija vitamina C linolnom kiselinom - određivanje antioksidativnih i difuzionih svojstava L-askorbil-linolata
VL  - 45
IS  - 1
SP  - 1
EP  - 10
DO  - 10.5937/FFR1801001C
UR  - Kon_157
ER  - 
@article{
author = "Ćorović, Marija and Milivojević, Ana and Carević, Milica B. and Banjanac, Katarina and Vujisić, Ljubodrag V. and Pjanović, Rada V. and Bezbradica, Dejan",
year = "2018",
abstract = "Lipophilic derivatives of vitamin C are additives with antioxidant properties, attractive for application in food, cosmetics and pharmaceutics. They could be synthesized in lipase-catalyzed processes by using various acyl donors. Hereby, we present application of linoleic acid, which is polyunsaturated fatty acid essential in human nutrition, for esterification of vitamin C catalyzed by immobilized enzyme preparation Novozym® 435 in acetone. Highest specific ester yield, 9.7 mmol/g of immobilized lipase, was accomplished with 0.15 M of vitamin C, 0.6 M of linoleic acid, 3 g/l of enzyme and 0.07% (v/v) of water, at 60°C. NMR analyses of purified product proved that synthesized molecule was identical to 6-O-ascorbyl linoleate. Capacity of ester for scavenging 2,2-diphenyl-1-picrylhydrazyl radicals was two times higher comparing to parent molecule, vitamin C. Its diffusion coefficient, determined using Franz cell and cellulose acetate membrane, was 40% higher than palmitate and 62% higher than oleate. Obtained results showed that L-ascorbyl linoleate could be successfully synthesized in biocatalyzed processes. Furthermore, it was demonstrated that it possess high potential for application in different lipophilic products due to its liposolubility, high antioxidant efficiency and good diffusion properties., Lipofilni derivati vitamina C su aditivi sa antioksidativnim dejstvom pogodni za primenu u prehrambenim, kozmetičkim i farmaceutskim proizvodima. Mogu biti sintetisani u procesima katalizovanim lipazama korišćenjem različitih acil-donora. U ovom radu, opisana je primena linolne kiseline, polinezasićene masne kiseline esencijalne u ljudskoj ishrani, u esterifikaciji vitamina C katalizovanoj imobilisanim enzimskim preparatom Novozym® 435 u acetonu. Najviši specifični prinos estra od 9,7 mmol/g imobilisane lipaze, ostvaren je sa 0,15 M vitamina C, 0,6 M linolne kiseline, 3 g/l enzima i 0,07 zapr. % vode, na 60°C. NMR analize prečišćenog proizvoda dokazale su da je sintetisani molekul identičan 6-O-askorbil-linolatu. Kapacitet estra za vezivanje 2,2- difenil-1-pikrilhidrazil radikala bio je dva puta viši u odnosu na sam vitamin C. Njegov koeficijent difuzije, određen korišćenjem Franz-ove ćelije i celuloza-acetatne membrane, bio je za 40% viši u odnosu na palmitat i za 62% u odnosu na oleat. Ostvareni rezultati pokazali su da L-askorbil-linolat može uspešno biti sintetisan u biokatalizovanom procesu. Pored toga, dokazano je da ovaj estar poseduje značajan potencijal za primenu u različitim lipofilnim proizvodima zbog svoje liposolubilnosti, snažnog antioksidativnog dejstva i pogodnih difuzionih karakteristika.",
journal = "Food and Feed Research",
title = "Enzymatic lipophilization of vitamin C with linoleic acid: Determination of antioxidant and diffusion properties of L-ascorbyl linoleate, enzimska lipofilizacija vitamina C linolnom kiselinom - određivanje antioksidativnih i difuzionih svojstava L-askorbil-linolata",
volume = "45",
number = "1",
pages = "1-10",
doi = "10.5937/FFR1801001C",
url = "Kon_157"
}
Ćorović, M., Milivojević, A., Carević, M. B., Banjanac, K., Vujisić, L. V., Pjanović, R. V.,& Bezbradica, D.. (2018). Enzymatic lipophilization of vitamin C with linoleic acid: Determination of antioxidant and diffusion properties of L-ascorbyl linoleate. in Food and Feed Research, 45(1), 1-10.
https://doi.org/10.5937/FFR1801001C
Kon_157
Ćorović M, Milivojević A, Carević MB, Banjanac K, Vujisić LV, Pjanović RV, Bezbradica D. Enzymatic lipophilization of vitamin C with linoleic acid: Determination of antioxidant and diffusion properties of L-ascorbyl linoleate. in Food and Feed Research. 2018;45(1):1-10.
doi:10.5937/FFR1801001C
Kon_157 .
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