TY  - JOUR
AU  - Mijatović, Aleksandar
AU  - Cakovic, Angelina
AU  - Lolić, Aleksandar
AU  - Sretenovic, Snezana
AU  - Zivanovic, Marko
AU  - Petrović, Biljana
AU  - Bogojeski, Jovana
AU  - Seklic, Dragana
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6458
AB  - Three Schiff base Cu(II) complexes, (N,N’-bis(acetylacetone)­propyl­enediimine)copper(II) complex, [Cu(acac2pn)] (1), (N,N'-bis-(ben­zoyl­acet­one)propylenediimine)copper(II) complex, [Cu(phacac2pn)] (2) and (N,N’-bis-(trifluoroacetylacetone)propylenediimine)­copper(II) complex, [Cu(tfacac2pn)] (3), were used to investigate the interactions with calf thymus DNA (ct-DNA) and bovine serum albumin (BSA) using the electronic absorption and spectro­scopic fluorescence methods. UV–Vis absorption studies showed that studied complexes interact with DNA molecule and exhibit moderate binding affinity. Fluorescence studies of complexes 1–3 also showed a possibility for DNA int­ercalation as well as a relatively high binding ability toward BSA. Among the tested complexes, the highest affinity for DNA and BSA molecules was shown by complex 1. Cytotoxic analyses, performed on human colorectal carcinoma HCT-116 and healthy lung fibroblast MRC-5 cell lines, showed that complex 2 exhibited activity on both cell lines, while complexes 1 and 3 did not show any activity.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - DNA/BSA interactions and cytotoxic studies of tetradentate N,N,O,O-Schiff base copper(II) complexes: Scientific paper
VL  - 88
IS  - 12
SP  - 1307
EP  - 1317
DO  - 10.2298/JSC230614063M
ER  - 

@article{
author = "Mijatović, Aleksandar and Cakovic, Angelina and Lolić, Aleksandar and Sretenovic, Snezana and Zivanovic, Marko and Petrović, Biljana and Bogojeski, Jovana and Seklic, Dragana",
year = "2023",
abstract = "Three Schiff base Cu(II) complexes, (N,N’-bis(acetylacetone)­propyl­enediimine)copper(II) complex, [Cu(acac2pn)] (1), (N,N'-bis-(ben­zoyl­acet­one)propylenediimine)copper(II) complex, [Cu(phacac2pn)] (2) and (N,N’-bis-(trifluoroacetylacetone)propylenediimine)­copper(II) complex, [Cu(tfacac2pn)] (3), were used to investigate the interactions with calf thymus DNA (ct-DNA) and bovine serum albumin (BSA) using the electronic absorption and spectro­scopic fluorescence methods. UV–Vis absorption studies showed that studied complexes interact with DNA molecule and exhibit moderate binding affinity. Fluorescence studies of complexes 1–3 also showed a possibility for DNA int­ercalation as well as a relatively high binding ability toward BSA. Among the tested complexes, the highest affinity for DNA and BSA molecules was shown by complex 1. Cytotoxic analyses, performed on human colorectal carcinoma HCT-116 and healthy lung fibroblast MRC-5 cell lines, showed that complex 2 exhibited activity on both cell lines, while complexes 1 and 3 did not show any activity.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "DNA/BSA interactions and cytotoxic studies of tetradentate N,N,O,O-Schiff base copper(II) complexes: Scientific paper",
volume = "88",
number = "12",
pages = "1307-1317",
doi = "10.2298/JSC230614063M"
}

Mijatović, A., Cakovic, A., Lolić, A., Sretenovic, S., Zivanovic, M., Petrović, B., Bogojeski, J.,& Seklic, D.. (2023). DNA/BSA interactions and cytotoxic studies of tetradentate N,N,O,O-Schiff base copper(II) complexes: Scientific paper. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 88(12), 1307-1317.
https://doi.org/10.2298/JSC230614063M

Mijatović A, Cakovic A, Lolić A, Sretenovic S, Zivanovic M, Petrović B, Bogojeski J, Seklic D. DNA/BSA interactions and cytotoxic studies of tetradentate N,N,O,O-Schiff base copper(II) complexes: Scientific paper. in Journal of the Serbian Chemical Society. 2023;88(12):1307-1317.
doi:10.2298/JSC230614063M .

Mijatović, Aleksandar, Cakovic, Angelina, Lolić, Aleksandar, Sretenovic, Snezana, Zivanovic, Marko, Petrović, Biljana, Bogojeski, Jovana, Seklic, Dragana, "DNA/BSA interactions and cytotoxic studies of tetradentate N,N,O,O-Schiff base copper(II) complexes: Scientific paper" in Journal of the Serbian Chemical Society, 88, no. 12 (2023):1307-1317,
https://doi.org/10.2298/JSC230614063M . .

TY  - JOUR
AU  - Kasalović, Marijana P.
AU  - Petrović, Angelina
AU  - Živković, Jelena M.
AU  - Kuckling, Linus
AU  - Jevtić, Verica V.
AU  - Bogojeski, Jovana
AU  - Leka, Zorica B.
AU  - Trifunović, Srećko R.
AU  - Pantelić, Nebojša Đ.
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4436
AB  - Dithiocarbamates, with their high lipophilic character and good chelating properties, could provide stabile transition metal complexes and enable these metal-based drugs to reach their biological targets. Palladium(II) and gold(III) complexes, due to its structural similarity with platinum(II)compounds, could be competitive candidates for implementing and developing new pharmacological agents. Herein, novel gold(III) complex with triammonium N-carboxyiminodiacetate as ligand has been synthesized and characterized by elemental analysis, molar conductivity measurements, FT-IR and 1H and 13C NMR spectroscopy. The proposed structure was examined and compared with analogue palladium(II) and zinc(II) complexes by density functional theory (B3LYP/def2tzvp). Additionally, DNA-binding studies by UV/Vis-spectrometer as well as ethidium-bromide (EB) and bovine serum albumin (BSA) quenching studies by spectrofluorometer were performed for gold(III), palladium(II) and zinc(II) dithiocarbamate complexes. The investigated complexes showed a good affinity to calf thymus DNA (CT-DNA) and BSA, with a higher affinity to BSA. Palladium(II) complex exhibited 5-fold a stronger affinity to DNA binding in comparison to zinc(II), but no significantly higher than gold(III) complex. Furthermore, palladium(II) and gold(III) complexes demonstrated a similar affinity toward BSA and these interactions are stronger than showed by zinc(II) complex.
PB  - Elsevier
T2  - Journal of Molecular Structure
T1  - Evaluation of DNA/BSA interactions and DFT calculations of gold(III), zinc(II) and palladium(II) complexes with triammonium N-dithiocarboxyiminodiacetate
VL  - 1229
SP  - 129622
DO  - 10.1016/j.molstruc.2020.129622
ER  - 

@article{
author = "Kasalović, Marijana P. and Petrović, Angelina and Živković, Jelena M. and Kuckling, Linus and Jevtić, Verica V. and Bogojeski, Jovana and Leka, Zorica B. and Trifunović, Srećko R. and Pantelić, Nebojša Đ.",
year = "2021",
abstract = "Dithiocarbamates, with their high lipophilic character and good chelating properties, could provide stabile transition metal complexes and enable these metal-based drugs to reach their biological targets. Palladium(II) and gold(III) complexes, due to its structural similarity with platinum(II)compounds, could be competitive candidates for implementing and developing new pharmacological agents. Herein, novel gold(III) complex with triammonium N-carboxyiminodiacetate as ligand has been synthesized and characterized by elemental analysis, molar conductivity measurements, FT-IR and 1H and 13C NMR spectroscopy. The proposed structure was examined and compared with analogue palladium(II) and zinc(II) complexes by density functional theory (B3LYP/def2tzvp). Additionally, DNA-binding studies by UV/Vis-spectrometer as well as ethidium-bromide (EB) and bovine serum albumin (BSA) quenching studies by spectrofluorometer were performed for gold(III), palladium(II) and zinc(II) dithiocarbamate complexes. The investigated complexes showed a good affinity to calf thymus DNA (CT-DNA) and BSA, with a higher affinity to BSA. Palladium(II) complex exhibited 5-fold a stronger affinity to DNA binding in comparison to zinc(II), but no significantly higher than gold(III) complex. Furthermore, palladium(II) and gold(III) complexes demonstrated a similar affinity toward BSA and these interactions are stronger than showed by zinc(II) complex.",
publisher = "Elsevier",
journal = "Journal of Molecular Structure",
title = "Evaluation of DNA/BSA interactions and DFT calculations of gold(III), zinc(II) and palladium(II) complexes with triammonium N-dithiocarboxyiminodiacetate",
volume = "1229",
pages = "129622",
doi = "10.1016/j.molstruc.2020.129622"
}

Kasalović, M. P., Petrović, A., Živković, J. M., Kuckling, L., Jevtić, V. V., Bogojeski, J., Leka, Z. B., Trifunović, S. R.,& Pantelić, N. Đ.. (2021). Evaluation of DNA/BSA interactions and DFT calculations of gold(III), zinc(II) and palladium(II) complexes with triammonium N-dithiocarboxyiminodiacetate. in Journal of Molecular Structure
Elsevier., 1229, 129622.
https://doi.org/10.1016/j.molstruc.2020.129622

Kasalović MP, Petrović A, Živković JM, Kuckling L, Jevtić VV, Bogojeski J, Leka ZB, Trifunović SR, Pantelić NĐ. Evaluation of DNA/BSA interactions and DFT calculations of gold(III), zinc(II) and palladium(II) complexes with triammonium N-dithiocarboxyiminodiacetate. in Journal of Molecular Structure. 2021;1229:129622.
doi:10.1016/j.molstruc.2020.129622 .

Kasalović, Marijana P., Petrović, Angelina, Živković, Jelena M., Kuckling, Linus, Jevtić, Verica V., Bogojeski, Jovana, Leka, Zorica B., Trifunović, Srećko R., Pantelić, Nebojša Đ., "Evaluation of DNA/BSA interactions and DFT calculations of gold(III), zinc(II) and palladium(II) complexes with triammonium N-dithiocarboxyiminodiacetate" in Journal of Molecular Structure, 1229 (2021):129622,
https://doi.org/10.1016/j.molstruc.2020.129622 . .

TY  - DATA
AU  - Kasalović, Marijana P.
AU  - Petrović, Angelina
AU  - Živković, Jelena M.
AU  - Kuckling, Linus
AU  - Jevtić, Verica V.
AU  - Bogojeski, Jovana
AU  - Leka, Zorica B.
AU  - Trifunović, Srećko R.
AU  - Pantelić, Nebojša Đ.
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4438
PB  - Elsevier
T2  - Journal of Molecular Structure
T1  - Supplementary data for the article: Kasalović, M. P.; Petrović, A.; Živković, J. M.; Kuckling, L.; Jevtić, V. V.; Bogojeski, J.; Leka, Z. B.; Trifunović, S. R.; Pantelić, N. Đ. Evaluation of DNA/BSA Interactions and DFT Calculations of Gold(III), Zinc(II) and Palladium(II) Complexes with Triammonium N-Dithiocarboxyiminodiacetate. Journal of Molecular Structure 2021, 1229, 129622. https://doi.org/10.1016/j.molstruc.2020.129622.
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4438
ER  - 

@misc{
author = "Kasalović, Marijana P. and Petrović, Angelina and Živković, Jelena M. and Kuckling, Linus and Jevtić, Verica V. and Bogojeski, Jovana and Leka, Zorica B. and Trifunović, Srećko R. and Pantelić, Nebojša Đ.",
year = "2021",
publisher = "Elsevier",
journal = "Journal of Molecular Structure",
title = "Supplementary data for the article: Kasalović, M. P.; Petrović, A.; Živković, J. M.; Kuckling, L.; Jevtić, V. V.; Bogojeski, J.; Leka, Z. B.; Trifunović, S. R.; Pantelić, N. Đ. Evaluation of DNA/BSA Interactions and DFT Calculations of Gold(III), Zinc(II) and Palladium(II) Complexes with Triammonium N-Dithiocarboxyiminodiacetate. Journal of Molecular Structure 2021, 1229, 129622. https://doi.org/10.1016/j.molstruc.2020.129622.",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4438"
}

Kasalović, M. P., Petrović, A., Živković, J. M., Kuckling, L., Jevtić, V. V., Bogojeski, J., Leka, Z. B., Trifunović, S. R.,& Pantelić, N. Đ.. (2021). Supplementary data for the article: Kasalović, M. P.; Petrović, A.; Živković, J. M.; Kuckling, L.; Jevtić, V. V.; Bogojeski, J.; Leka, Z. B.; Trifunović, S. R.; Pantelić, N. Đ. Evaluation of DNA/BSA Interactions and DFT Calculations of Gold(III), Zinc(II) and Palladium(II) Complexes with Triammonium N-Dithiocarboxyiminodiacetate. Journal of Molecular Structure 2021, 1229, 129622. https://doi.org/10.1016/j.molstruc.2020.129622.. in Journal of Molecular Structure
Elsevier..
https://hdl.handle.net/21.15107/rcub_cherry_4438

Kasalović MP, Petrović A, Živković JM, Kuckling L, Jevtić VV, Bogojeski J, Leka ZB, Trifunović SR, Pantelić NĐ. Supplementary data for the article: Kasalović, M. P.; Petrović, A.; Živković, J. M.; Kuckling, L.; Jevtić, V. V.; Bogojeski, J.; Leka, Z. B.; Trifunović, S. R.; Pantelić, N. Đ. Evaluation of DNA/BSA Interactions and DFT Calculations of Gold(III), Zinc(II) and Palladium(II) Complexes with Triammonium N-Dithiocarboxyiminodiacetate. Journal of Molecular Structure 2021, 1229, 129622. https://doi.org/10.1016/j.molstruc.2020.129622.. in Journal of Molecular Structure. 2021;.
https://hdl.handle.net/21.15107/rcub_cherry_4438 .

Kasalović, Marijana P., Petrović, Angelina, Živković, Jelena M., Kuckling, Linus, Jevtić, Verica V., Bogojeski, Jovana, Leka, Zorica B., Trifunović, Srećko R., Pantelić, Nebojša Đ., "Supplementary data for the article: Kasalović, M. P.; Petrović, A.; Živković, J. M.; Kuckling, L.; Jevtić, V. V.; Bogojeski, J.; Leka, Z. B.; Trifunović, S. R.; Pantelić, N. Đ. Evaluation of DNA/BSA Interactions and DFT Calculations of Gold(III), Zinc(II) and Palladium(II) Complexes with Triammonium N-Dithiocarboxyiminodiacetate. Journal of Molecular Structure 2021, 1229, 129622. https://doi.org/10.1016/j.molstruc.2020.129622." in Journal of Molecular Structure (2021),
https://hdl.handle.net/21.15107/rcub_cherry_4438 .