TY  - JOUR
AU  - Veljović, Elma
AU  - Špirtović-Halilović, Selma
AU  - Muratovic, Samija
AU  - Zulj, Lidija Valek
AU  - Roca, Sunčica
AU  - Trifunović, Snežana S.
AU  - Osmanović, Amar
AU  - Završnik, Davorka
PY  - 2015
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1743
AB  - Oxidative stress is directly related to several diseases and symptoms, where antioxidant compounds, such as xanthenes, may become important in prevention and/or treatmant. Ten biologically active 9-aryl substituted 2,6,7-trihydroxyxanthen-3-one derivatives were synthesized using reliable one-pot synthesis and their structures were confirmed by IR, H-1 and C-13 NMR spectroscopy and mass spectrometry. Some of the synthesized compounds were scanned for their antioxidant potency using electrochemical method cyclic voltammetry of immobilized microparticles. Substitution of hydrogen at the phenyl ring of 2,6,7-trihydroxy-9-phenylxanthen-3-one with an electron-donating group affected the reducing power of the compounds by lowering the biological oxidation potential. These results signify the importance of xanthen-3-one derivatives as antioxidant agents and their further biological evaluation.
PB  - Croatian Chemical Soc, Zagreb
T2  - Croatica Chemica Acta
T1  - 9-Aryl Substituted Hydroxylated Xanthen-3-ones: Synthesis, Structure and Antioxidant Potency Evaluation
VL  - 88
IS  - 2
SP  - 121
EP  - 127
DO  - 10.5562/cca2595
ER  - 

@article{
author = "Veljović, Elma and Špirtović-Halilović, Selma and Muratovic, Samija and Zulj, Lidija Valek and Roca, Sunčica and Trifunović, Snežana S. and Osmanović, Amar and Završnik, Davorka",
year = "2015",
abstract = "Oxidative stress is directly related to several diseases and symptoms, where antioxidant compounds, such as xanthenes, may become important in prevention and/or treatmant. Ten biologically active 9-aryl substituted 2,6,7-trihydroxyxanthen-3-one derivatives were synthesized using reliable one-pot synthesis and their structures were confirmed by IR, H-1 and C-13 NMR spectroscopy and mass spectrometry. Some of the synthesized compounds were scanned for their antioxidant potency using electrochemical method cyclic voltammetry of immobilized microparticles. Substitution of hydrogen at the phenyl ring of 2,6,7-trihydroxy-9-phenylxanthen-3-one with an electron-donating group affected the reducing power of the compounds by lowering the biological oxidation potential. These results signify the importance of xanthen-3-one derivatives as antioxidant agents and their further biological evaluation.",
publisher = "Croatian Chemical Soc, Zagreb",
journal = "Croatica Chemica Acta",
title = "9-Aryl Substituted Hydroxylated Xanthen-3-ones: Synthesis, Structure and Antioxidant Potency Evaluation",
volume = "88",
number = "2",
pages = "121-127",
doi = "10.5562/cca2595"
}

Veljović, E., Špirtović-Halilović, S., Muratovic, S., Zulj, L. V., Roca, S., Trifunović, S. S., Osmanović, A.,& Završnik, D.. (2015). 9-Aryl Substituted Hydroxylated Xanthen-3-ones: Synthesis, Structure and Antioxidant Potency Evaluation. in Croatica Chemica Acta
Croatian Chemical Soc, Zagreb., 88(2), 121-127.
https://doi.org/10.5562/cca2595

Veljović E, Špirtović-Halilović S, Muratovic S, Zulj LV, Roca S, Trifunović SS, Osmanović A, Završnik D. 9-Aryl Substituted Hydroxylated Xanthen-3-ones: Synthesis, Structure and Antioxidant Potency Evaluation. in Croatica Chemica Acta. 2015;88(2):121-127.
doi:10.5562/cca2595 .

Veljović, Elma, Špirtović-Halilović, Selma, Muratovic, Samija, Zulj, Lidija Valek, Roca, Sunčica, Trifunović, Snežana S., Osmanović, Amar, Završnik, Davorka, "9-Aryl Substituted Hydroxylated Xanthen-3-ones: Synthesis, Structure and Antioxidant Potency Evaluation" in Croatica Chemica Acta, 88, no. 2 (2015):121-127,
https://doi.org/10.5562/cca2595 . .