TY  - JOUR
AU  - Trifunović, Snežana S.
AU  - Vajs, Vlatka
AU  - Macura, S.
AU  - Juranić, N.
AU  - Djarmati, Z
AU  - Jankov, Ratko M.
AU  - Milosavljevic, S
PY  - 1998
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/400
AB  - The isolation of two oxidation products of hyperforin from the aerial parts of Hypericum perforatum and their structure determination by means of 2D NMR methods is reported. The products had the same 1-(2-methyl-1-oxopropyl)-2,12-dioxo-3,10 beta-bis(3-methyl-2-butenyl)-11 beta-methyl-11 alpha-(4-methyl-3-pentenyl)-5-oxatricyclo[6.3.1.0(4.8)]-3-dodecene skeleton. In addition, one of them, with the same number of carbons as hyperforin (C35H52O5), contained a 1-methyl-1-hydroxyethyl group in the 6 beta-position, whereas the other compound (a hemiacetal, C32H46O5), presumably a degradation product of hyperforin, exhibited a 6-hydroxy function. The latter was an inseparable mixture of 6 alpha- and 6 beta-hydroxy epimers undergoing (according to phase sensitive NOESY) mutual :interconversion. (C) 1998 Elsevier Science Ltd. All rights reserved.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Phytochemistry
T1  - Oxidation products of hyperforin from Hypericum perforatum
VL  - 49
IS  - 5
SP  - 1305
EP  - 1310
DO  - 10.1016/S0031-9422(97)00903-5
ER  - 

@article{
author = "Trifunović, Snežana S. and Vajs, Vlatka and Macura, S. and Juranić, N. and Djarmati, Z and Jankov, Ratko M. and Milosavljevic, S",
year = "1998",
abstract = "The isolation of two oxidation products of hyperforin from the aerial parts of Hypericum perforatum and their structure determination by means of 2D NMR methods is reported. The products had the same 1-(2-methyl-1-oxopropyl)-2,12-dioxo-3,10 beta-bis(3-methyl-2-butenyl)-11 beta-methyl-11 alpha-(4-methyl-3-pentenyl)-5-oxatricyclo[6.3.1.0(4.8)]-3-dodecene skeleton. In addition, one of them, with the same number of carbons as hyperforin (C35H52O5), contained a 1-methyl-1-hydroxyethyl group in the 6 beta-position, whereas the other compound (a hemiacetal, C32H46O5), presumably a degradation product of hyperforin, exhibited a 6-hydroxy function. The latter was an inseparable mixture of 6 alpha- and 6 beta-hydroxy epimers undergoing (according to phase sensitive NOESY) mutual :interconversion. (C) 1998 Elsevier Science Ltd. All rights reserved.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Phytochemistry",
title = "Oxidation products of hyperforin from Hypericum perforatum",
volume = "49",
number = "5",
pages = "1305-1310",
doi = "10.1016/S0031-9422(97)00903-5"
}

Trifunović, S. S., Vajs, V., Macura, S., Juranić, N., Djarmati, Z., Jankov, R. M.,& Milosavljevic, S.. (1998). Oxidation products of hyperforin from Hypericum perforatum. in Phytochemistry
Pergamon-Elsevier Science Ltd, Oxford., 49(5), 1305-1310.
https://doi.org/10.1016/S0031-9422(97)00903-5

Trifunović SS, Vajs V, Macura S, Juranić N, Djarmati Z, Jankov RM, Milosavljevic S. Oxidation products of hyperforin from Hypericum perforatum. in Phytochemistry. 1998;49(5):1305-1310.
doi:10.1016/S0031-9422(97)00903-5 .

Trifunović, Snežana S., Vajs, Vlatka, Macura, S., Juranić, N., Djarmati, Z, Jankov, Ratko M., Milosavljevic, S, "Oxidation products of hyperforin from Hypericum perforatum" in Phytochemistry, 49, no. 5 (1998):1305-1310,
https://doi.org/10.1016/S0031-9422(97)00903-5 . .