TY  - DATA
AU  - Jeremić, Marko
AU  - Pešić, Milica
AU  - Dinić, Jelena
AU  - Banković, Jasna
AU  - Novaković, Irena T.
AU  - Šegan, Dejan M.
AU  - Sladić, Dušan
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3612
PB  - Elsevier France-Editions Scientifiques Medicales Elsevier, Paris
T2  - European Journal of Medicinal Chemistry
T1  - Supplementary material for the article: Jeremić, M.; Pešić, M.; Dinić, J.; Banković, J.; Novakovićc, I.; Šegan, D.; Sladić, D. Simple Avarone Mimetics as Selective Agents against Multidrug Resistant Cancer Cells. European Journal of Medicinal Chemistry 2016, 118, 107–120. https://doi.org/10.1016/j.ejmech.2016.04.011
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3612
ER  - 

@misc{
author = "Jeremić, Marko and Pešić, Milica and Dinić, Jelena and Banković, Jasna and Novaković, Irena T. and Šegan, Dejan M. and Sladić, Dušan",
year = "2016",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Paris",
journal = "European Journal of Medicinal Chemistry",
title = "Supplementary material for the article: Jeremić, M.; Pešić, M.; Dinić, J.; Banković, J.; Novakovićc, I.; Šegan, D.; Sladić, D. Simple Avarone Mimetics as Selective Agents against Multidrug Resistant Cancer Cells. European Journal of Medicinal Chemistry 2016, 118, 107–120. https://doi.org/10.1016/j.ejmech.2016.04.011",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3612"
}

Jeremić, M., Pešić, M., Dinić, J., Banković, J., Novaković, I. T., Šegan, D. M.,& Sladić, D.. (2016). Supplementary material for the article: Jeremić, M.; Pešić, M.; Dinić, J.; Banković, J.; Novakovićc, I.; Šegan, D.; Sladić, D. Simple Avarone Mimetics as Selective Agents against Multidrug Resistant Cancer Cells. European Journal of Medicinal Chemistry 2016, 118, 107–120. https://doi.org/10.1016/j.ejmech.2016.04.011. in European Journal of Medicinal Chemistry
Elsevier France-Editions Scientifiques Medicales Elsevier, Paris..
https://hdl.handle.net/21.15107/rcub_cherry_3612

Jeremić M, Pešić M, Dinić J, Banković J, Novaković IT, Šegan DM, Sladić D. Supplementary material for the article: Jeremić, M.; Pešić, M.; Dinić, J.; Banković, J.; Novakovićc, I.; Šegan, D.; Sladić, D. Simple Avarone Mimetics as Selective Agents against Multidrug Resistant Cancer Cells. European Journal of Medicinal Chemistry 2016, 118, 107–120. https://doi.org/10.1016/j.ejmech.2016.04.011. in European Journal of Medicinal Chemistry. 2016;.
https://hdl.handle.net/21.15107/rcub_cherry_3612 .

Jeremić, Marko, Pešić, Milica, Dinić, Jelena, Banković, Jasna, Novaković, Irena T., Šegan, Dejan M., Sladić, Dušan, "Supplementary material for the article: Jeremić, M.; Pešić, M.; Dinić, J.; Banković, J.; Novakovićc, I.; Šegan, D.; Sladić, D. Simple Avarone Mimetics as Selective Agents against Multidrug Resistant Cancer Cells. European Journal of Medicinal Chemistry 2016, 118, 107–120. https://doi.org/10.1016/j.ejmech.2016.04.011" in European Journal of Medicinal Chemistry (2016),
https://hdl.handle.net/21.15107/rcub_cherry_3612 .

TY  - JOUR
AU  - Jeremić, Marko
AU  - Pešić, Milica
AU  - Dinić, Jelena
AU  - Banković, Jasna
AU  - Novaković, Irena T.
AU  - Šegan, Dejan M.
AU  - Sladić, Dušan
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2256
AB  - In this work, synthesis of alkylamino and aralkylamino derivatives of sesquiterpene quinone avarone and its model compound tert-butylquinone was described. For all obtained derivatives biological activity was studied. Cytotoxic activity of the synthesized derivatives towards multidrug resistant MDR human non small cell lung carcinoma NCI-H460/R cells, their sensitive counterpart NCI-H460 and human normal keratinocytes (HaCaT) as well as detection of cell death superoxide anion generation were investigated. Antimicrobial activity towards Gram positive and Gram negative bacteria and fungal cultures was determined. The results showed that strong cytotoxic activity toward cancer cells was improved with simple avarone mimetics. Some derivatives were selective towards MDR cancer cells. The most active derivatives induced apoptosis in both cancer cell lines, but not in normal cells. Superoxide production was induced by 2,6-disubstituted compounds in MDR cancer cells and not by less active 2,5-disubstituted compounds and was accompanied by the collapse of the mitochondrial transmembrane potential. Two tert-butylquinone derivatives were particularly selective towards MDR cancer cells. Some tert-butylquinone derivatives exhibited a strong antimicrobial activity. (C) 2016 Elsevier Masson SAS. All rights reserved.
PB  - Elsevier France-Editions Scientifiques Medicales Elsevier, Paris
T2  - European Journal of Medicinal Chemistry
T1  - Simple avarone mimetics as selective agents against multidrug resistant cancer cells
VL  - 118
SP  - 107
EP  - 120
DO  - 10.1016/j.ejmech.2016.04.011
ER  - 

@article{
author = "Jeremić, Marko and Pešić, Milica and Dinić, Jelena and Banković, Jasna and Novaković, Irena T. and Šegan, Dejan M. and Sladić, Dušan",
year = "2016",
abstract = "In this work, synthesis of alkylamino and aralkylamino derivatives of sesquiterpene quinone avarone and its model compound tert-butylquinone was described. For all obtained derivatives biological activity was studied. Cytotoxic activity of the synthesized derivatives towards multidrug resistant MDR human non small cell lung carcinoma NCI-H460/R cells, their sensitive counterpart NCI-H460 and human normal keratinocytes (HaCaT) as well as detection of cell death superoxide anion generation were investigated. Antimicrobial activity towards Gram positive and Gram negative bacteria and fungal cultures was determined. The results showed that strong cytotoxic activity toward cancer cells was improved with simple avarone mimetics. Some derivatives were selective towards MDR cancer cells. The most active derivatives induced apoptosis in both cancer cell lines, but not in normal cells. Superoxide production was induced by 2,6-disubstituted compounds in MDR cancer cells and not by less active 2,5-disubstituted compounds and was accompanied by the collapse of the mitochondrial transmembrane potential. Two tert-butylquinone derivatives were particularly selective towards MDR cancer cells. Some tert-butylquinone derivatives exhibited a strong antimicrobial activity. (C) 2016 Elsevier Masson SAS. All rights reserved.",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Paris",
journal = "European Journal of Medicinal Chemistry",
title = "Simple avarone mimetics as selective agents against multidrug resistant cancer cells",
volume = "118",
pages = "107-120",
doi = "10.1016/j.ejmech.2016.04.011"
}

Jeremić, M., Pešić, M., Dinić, J., Banković, J., Novaković, I. T., Šegan, D. M.,& Sladić, D.. (2016). Simple avarone mimetics as selective agents against multidrug resistant cancer cells. in European Journal of Medicinal Chemistry
Elsevier France-Editions Scientifiques Medicales Elsevier, Paris., 118, 107-120.
https://doi.org/10.1016/j.ejmech.2016.04.011

Jeremić M, Pešić M, Dinić J, Banković J, Novaković IT, Šegan DM, Sladić D. Simple avarone mimetics as selective agents against multidrug resistant cancer cells. in European Journal of Medicinal Chemistry. 2016;118:107-120.
doi:10.1016/j.ejmech.2016.04.011 .

Jeremić, Marko, Pešić, Milica, Dinić, Jelena, Banković, Jasna, Novaković, Irena T., Šegan, Dejan M., Sladić, Dušan, "Simple avarone mimetics as selective agents against multidrug resistant cancer cells" in European Journal of Medicinal Chemistry, 118 (2016):107-120,
https://doi.org/10.1016/j.ejmech.2016.04.011 . .

TY  - JOUR
AU  - Vilipić, Jovana
AU  - Novaković, Irena T.
AU  - Stanojković, Tatjana
AU  - Matić, Ivana Z.
AU  - Šegan, Dejan M.
AU  - Kljajić, Zoran
AU  - Sladić, Dušan
PY  - 2015
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3438
AB  - A series of eighteen derivatives of marine sesquiterpene quinone avarone and its model system tert-butylquinone with amino acids has been synthesized by nucleophilic addition of amino acids to the quinones. In vitro cytotoxic activity toward human cancer cell lines (HeLa, A549, Fem-X, 1(562, MDA-MB-453) and normal MRC-5 cell line was determined. Several compounds showed very strong inhibitory activity with IC50 values less than 10 mu M. Avarone derivatives were more active than the corresponding tert-butylquinone derivatives. The results of the cytofluorimetric analysis of cell cycle of HeLa cells showed that apoptosis might be one of possible mechanism of action of these compounds in cancer cells. In order to examine the influence of caspases on cell death, the apoptotic mechanisms induced by the tested compounds were determined using specific caspases 3, 8 and 9 inhibitors. For all compounds antibacterial activities against six strains of Gram-positive and four strains of Gram-negative bacteria were determined, as well as antifungal activity against three fungal species.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Bioorganic and Medicinal Chemistry
T1  - Synthesis and biological activity of amino acid derivatives of avarone and its model compound
VL  - 23
IS  - 21
SP  - 6930
EP  - 6942
DO  - 10.1016/j.bmc.2015.09.044
ER  - 

@article{
author = "Vilipić, Jovana and Novaković, Irena T. and Stanojković, Tatjana and Matić, Ivana Z. and Šegan, Dejan M. and Kljajić, Zoran and Sladić, Dušan",
year = "2015",
abstract = "A series of eighteen derivatives of marine sesquiterpene quinone avarone and its model system tert-butylquinone with amino acids has been synthesized by nucleophilic addition of amino acids to the quinones. In vitro cytotoxic activity toward human cancer cell lines (HeLa, A549, Fem-X, 1(562, MDA-MB-453) and normal MRC-5 cell line was determined. Several compounds showed very strong inhibitory activity with IC50 values less than 10 mu M. Avarone derivatives were more active than the corresponding tert-butylquinone derivatives. The results of the cytofluorimetric analysis of cell cycle of HeLa cells showed that apoptosis might be one of possible mechanism of action of these compounds in cancer cells. In order to examine the influence of caspases on cell death, the apoptotic mechanisms induced by the tested compounds were determined using specific caspases 3, 8 and 9 inhibitors. For all compounds antibacterial activities against six strains of Gram-positive and four strains of Gram-negative bacteria were determined, as well as antifungal activity against three fungal species.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Bioorganic and Medicinal Chemistry",
title = "Synthesis and biological activity of amino acid derivatives of avarone and its model compound",
volume = "23",
number = "21",
pages = "6930-6942",
doi = "10.1016/j.bmc.2015.09.044"
}

Vilipić, J., Novaković, I. T., Stanojković, T., Matić, I. Z., Šegan, D. M., Kljajić, Z.,& Sladić, D.. (2015). Synthesis and biological activity of amino acid derivatives of avarone and its model compound. in Bioorganic and Medicinal Chemistry
Pergamon-Elsevier Science Ltd, Oxford., 23(21), 6930-6942.
https://doi.org/10.1016/j.bmc.2015.09.044

Vilipić J, Novaković IT, Stanojković T, Matić IZ, Šegan DM, Kljajić Z, Sladić D. Synthesis and biological activity of amino acid derivatives of avarone and its model compound. in Bioorganic and Medicinal Chemistry. 2015;23(21):6930-6942.
doi:10.1016/j.bmc.2015.09.044 .

Vilipić, Jovana, Novaković, Irena T., Stanojković, Tatjana, Matić, Ivana Z., Šegan, Dejan M., Kljajić, Zoran, Sladić, Dušan, "Synthesis and biological activity of amino acid derivatives of avarone and its model compound" in Bioorganic and Medicinal Chemistry, 23, no. 21 (2015):6930-6942,
https://doi.org/10.1016/j.bmc.2015.09.044 . .

TY  - DATA
AU  - Vilipić, Jovana
AU  - Novaković, Irena T.
AU  - Stanojković, Tatjana
AU  - Matić, Ivana Z.
AU  - Šegan, Dejan M.
AU  - Kljajić, Zoran
AU  - Sladić, Dušan
PY  - 2015
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3439
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Bioorganic and Medicinal Chemistry
T1  - Supplementary data for article: Vilipić, J.; Novaković, I.; Stanojković, T.; Matić, I.; Šegan, D.; Kljajić, Z.; Sladić, D. Synthesis and Biological Activity of Amino Acid Derivatives of Avarone and Its Model Compound. Bioorganic and Medicinal Chemistry 2015, 23 (21), 6930–6942. https://doi.org/10.1016/j.bmc.2015.09.044
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3439
ER  - 

@misc{
author = "Vilipić, Jovana and Novaković, Irena T. and Stanojković, Tatjana and Matić, Ivana Z. and Šegan, Dejan M. and Kljajić, Zoran and Sladić, Dušan",
year = "2015",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Bioorganic and Medicinal Chemistry",
title = "Supplementary data for article: Vilipić, J.; Novaković, I.; Stanojković, T.; Matić, I.; Šegan, D.; Kljajić, Z.; Sladić, D. Synthesis and Biological Activity of Amino Acid Derivatives of Avarone and Its Model Compound. Bioorganic and Medicinal Chemistry 2015, 23 (21), 6930–6942. https://doi.org/10.1016/j.bmc.2015.09.044",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3439"
}

Vilipić, J., Novaković, I. T., Stanojković, T., Matić, I. Z., Šegan, D. M., Kljajić, Z.,& Sladić, D.. (2015). Supplementary data for article: Vilipić, J.; Novaković, I.; Stanojković, T.; Matić, I.; Šegan, D.; Kljajić, Z.; Sladić, D. Synthesis and Biological Activity of Amino Acid Derivatives of Avarone and Its Model Compound. Bioorganic and Medicinal Chemistry 2015, 23 (21), 6930–6942. https://doi.org/10.1016/j.bmc.2015.09.044. in Bioorganic and Medicinal Chemistry
Pergamon-Elsevier Science Ltd, Oxford..
https://hdl.handle.net/21.15107/rcub_cherry_3439

Vilipić J, Novaković IT, Stanojković T, Matić IZ, Šegan DM, Kljajić Z, Sladić D. Supplementary data for article: Vilipić, J.; Novaković, I.; Stanojković, T.; Matić, I.; Šegan, D.; Kljajić, Z.; Sladić, D. Synthesis and Biological Activity of Amino Acid Derivatives of Avarone and Its Model Compound. Bioorganic and Medicinal Chemistry 2015, 23 (21), 6930–6942. https://doi.org/10.1016/j.bmc.2015.09.044. in Bioorganic and Medicinal Chemistry. 2015;.
https://hdl.handle.net/21.15107/rcub_cherry_3439 .

Vilipić, Jovana, Novaković, Irena T., Stanojković, Tatjana, Matić, Ivana Z., Šegan, Dejan M., Kljajić, Zoran, Sladić, Dušan, "Supplementary data for article: Vilipić, J.; Novaković, I.; Stanojković, T.; Matić, I.; Šegan, D.; Kljajić, Z.; Sladić, D. Synthesis and Biological Activity of Amino Acid Derivatives of Avarone and Its Model Compound. Bioorganic and Medicinal Chemistry 2015, 23 (21), 6930–6942. https://doi.org/10.1016/j.bmc.2015.09.044" in Bioorganic and Medicinal Chemistry (2015),
https://hdl.handle.net/21.15107/rcub_cherry_3439 .

TY  - JOUR
AU  - Vilipić, Jovana
AU  - Novaković, Irena T.
AU  - Stanojković, Tatjana
AU  - Matić, Ivana Z.
AU  - Šegan, Dejan M.
AU  - Kljajić, Zoran
AU  - Sladić, Dušan
PY  - 2015
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1997
AB  - A series of eighteen derivatives of marine sesquiterpene quinone avarone and its model system tert-butylquinone with amino acids has been synthesized by nucleophilic addition of amino acids to the quinones. In vitro cytotoxic activity toward human cancer cell lines (HeLa, A549, Fem-X, 1(562, MDA-MB-453) and normal MRC-5 cell line was determined. Several compounds showed very strong inhibitory activity with IC50 values less than 10 mu M. Avarone derivatives were more active than the corresponding tert-butylquinone derivatives. The results of the cytofluorimetric analysis of cell cycle of HeLa cells showed that apoptosis might be one of possible mechanism of action of these compounds in cancer cells. In order to examine the influence of caspases on cell death, the apoptotic mechanisms induced by the tested compounds were determined using specific caspases 3, 8 and 9 inhibitors. For all compounds antibacterial activities against six strains of Gram-positive and four strains of Gram-negative bacteria were determined, as well as antifungal activity against three fungal species.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Bioorganic and Medicinal Chemistry
T1  - Synthesis and biological activity of amino acid derivatives of avarone and its model compound
VL  - 23
IS  - 21
SP  - 6930
EP  - 6942
DO  - 10.1016/j.bmc.2015.09.044
ER  - 

@article{
author = "Vilipić, Jovana and Novaković, Irena T. and Stanojković, Tatjana and Matić, Ivana Z. and Šegan, Dejan M. and Kljajić, Zoran and Sladić, Dušan",
year = "2015",
abstract = "A series of eighteen derivatives of marine sesquiterpene quinone avarone and its model system tert-butylquinone with amino acids has been synthesized by nucleophilic addition of amino acids to the quinones. In vitro cytotoxic activity toward human cancer cell lines (HeLa, A549, Fem-X, 1(562, MDA-MB-453) and normal MRC-5 cell line was determined. Several compounds showed very strong inhibitory activity with IC50 values less than 10 mu M. Avarone derivatives were more active than the corresponding tert-butylquinone derivatives. The results of the cytofluorimetric analysis of cell cycle of HeLa cells showed that apoptosis might be one of possible mechanism of action of these compounds in cancer cells. In order to examine the influence of caspases on cell death, the apoptotic mechanisms induced by the tested compounds were determined using specific caspases 3, 8 and 9 inhibitors. For all compounds antibacterial activities against six strains of Gram-positive and four strains of Gram-negative bacteria were determined, as well as antifungal activity against three fungal species.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Bioorganic and Medicinal Chemistry",
title = "Synthesis and biological activity of amino acid derivatives of avarone and its model compound",
volume = "23",
number = "21",
pages = "6930-6942",
doi = "10.1016/j.bmc.2015.09.044"
}

Vilipić, J., Novaković, I. T., Stanojković, T., Matić, I. Z., Šegan, D. M., Kljajić, Z.,& Sladić, D.. (2015). Synthesis and biological activity of amino acid derivatives of avarone and its model compound. in Bioorganic and Medicinal Chemistry
Pergamon-Elsevier Science Ltd, Oxford., 23(21), 6930-6942.
https://doi.org/10.1016/j.bmc.2015.09.044

Vilipić J, Novaković IT, Stanojković T, Matić IZ, Šegan DM, Kljajić Z, Sladić D. Synthesis and biological activity of amino acid derivatives of avarone and its model compound. in Bioorganic and Medicinal Chemistry. 2015;23(21):6930-6942.
doi:10.1016/j.bmc.2015.09.044 .

Vilipić, Jovana, Novaković, Irena T., Stanojković, Tatjana, Matić, Ivana Z., Šegan, Dejan M., Kljajić, Zoran, Sladić, Dušan, "Synthesis and biological activity of amino acid derivatives of avarone and its model compound" in Bioorganic and Medicinal Chemistry, 23, no. 21 (2015):6930-6942,
https://doi.org/10.1016/j.bmc.2015.09.044 . .

TY  - JOUR
AU  - Dusan, Velickovic
AU  - Nenad, Milosavic
AU  - Dejan, Bezbradica
AU  - Bihelović, Filip
AU  - Segal, Ann Marie
AU  - Šegan, Dejan M.
AU  - Trbojević-Ivić, Jovana
AU  - Aleksandra, Dimitrijevic
PY  - 2014
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1797
AB  - Our investigation of the catalytic properties of Saccharomyces cerevisiae alpha-glucosidase (AGL) using hydroxybenzyl alcohol (HBA) isomers as transglucosylation substrates and their glucosides in hydrolytic reactions demonstrated interesting findings pertaining to the aglycon specificity of this important enzyme. AGL specificity increased from the para(p)- to the ortho(o)-HBA isomer in transglucosylation, whereas such AGL aglycon specificity was not seen in hydrolysis, thus indicating that the second step of the reaction (i.e., binding of the glucosyl acceptor) is rate-determining. To study the influence of substitution pattern on AGL kinetics, we compared AGL specificity, inferred from kinetic constants, for HBA isomers and other aglycon substrates. The demonstrated inhibitory effects of HBA isomers and their corresponding glucosides on AGL-catalyzed hydrolysis of p-nitrophenyl a-glucoside (PNPG) suggest that HBA glucosides act as competitive, whereas HBA isomers are noncompetitive, inhibitors. As such, we postulate that aromatic moieties cannot bind to an active site unless an enzyme-glucosyl complex has already formed, but they can interact with other regions of the enzyme molecule resulting in inhibition.
PB  - Springer, New York
T2  - Applied Microbiology and Biotechnology
T1  - The specificity of alpha-glucosidase from Saccharomyces cerevisiae differs depending on the type of reaction: hydrolysis versus transglucosylation
VL  - 98
IS  - 14
SP  - 6317
EP  - 6328
DO  - 10.1007/s00253-014-5587-9
ER  - 

@article{
author = "Dusan, Velickovic and Nenad, Milosavic and Dejan, Bezbradica and Bihelović, Filip and Segal, Ann Marie and Šegan, Dejan M. and Trbojević-Ivić, Jovana and Aleksandra, Dimitrijevic",
year = "2014",
abstract = "Our investigation of the catalytic properties of Saccharomyces cerevisiae alpha-glucosidase (AGL) using hydroxybenzyl alcohol (HBA) isomers as transglucosylation substrates and their glucosides in hydrolytic reactions demonstrated interesting findings pertaining to the aglycon specificity of this important enzyme. AGL specificity increased from the para(p)- to the ortho(o)-HBA isomer in transglucosylation, whereas such AGL aglycon specificity was not seen in hydrolysis, thus indicating that the second step of the reaction (i.e., binding of the glucosyl acceptor) is rate-determining. To study the influence of substitution pattern on AGL kinetics, we compared AGL specificity, inferred from kinetic constants, for HBA isomers and other aglycon substrates. The demonstrated inhibitory effects of HBA isomers and their corresponding glucosides on AGL-catalyzed hydrolysis of p-nitrophenyl a-glucoside (PNPG) suggest that HBA glucosides act as competitive, whereas HBA isomers are noncompetitive, inhibitors. As such, we postulate that aromatic moieties cannot bind to an active site unless an enzyme-glucosyl complex has already formed, but they can interact with other regions of the enzyme molecule resulting in inhibition.",
publisher = "Springer, New York",
journal = "Applied Microbiology and Biotechnology",
title = "The specificity of alpha-glucosidase from Saccharomyces cerevisiae differs depending on the type of reaction: hydrolysis versus transglucosylation",
volume = "98",
number = "14",
pages = "6317-6328",
doi = "10.1007/s00253-014-5587-9"
}

Dusan, V., Nenad, M., Dejan, B., Bihelović, F., Segal, A. M., Šegan, D. M., Trbojević-Ivić, J.,& Aleksandra, D.. (2014). The specificity of alpha-glucosidase from Saccharomyces cerevisiae differs depending on the type of reaction: hydrolysis versus transglucosylation. in Applied Microbiology and Biotechnology
Springer, New York., 98(14), 6317-6328.
https://doi.org/10.1007/s00253-014-5587-9

Dusan V, Nenad M, Dejan B, Bihelović F, Segal AM, Šegan DM, Trbojević-Ivić J, Aleksandra D. The specificity of alpha-glucosidase from Saccharomyces cerevisiae differs depending on the type of reaction: hydrolysis versus transglucosylation. in Applied Microbiology and Biotechnology. 2014;98(14):6317-6328.
doi:10.1007/s00253-014-5587-9 .

Dusan, Velickovic, Nenad, Milosavic, Dejan, Bezbradica, Bihelović, Filip, Segal, Ann Marie, Šegan, Dejan M., Trbojević-Ivić, Jovana, Aleksandra, Dimitrijevic, "The specificity of alpha-glucosidase from Saccharomyces cerevisiae differs depending on the type of reaction: hydrolysis versus transglucosylation" in Applied Microbiology and Biotechnology, 98, no. 14 (2014):6317-6328,
https://doi.org/10.1007/s00253-014-5587-9 . .

TY  - JOUR
AU  - Pavlović, Marija
AU  - Dimitrijević, Aleksandra
AU  - Bezbradica, Dejan
AU  - Milosavić, Nenad
AU  - Gavrović-Jankulović, Marija
AU  - Šegan, Dejan M.
AU  - Veličković, Dušan
PY  - 2014
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1516
AB  - Benzyl alcohol, a potent anesthetic and bacteriostatic, can be efficiently glucosylated by alpha-glucosidase from Saccharomyces cerevisiae to produce benzyl alcohol alpha-glucoside with a 75% yield. However, while studying the transglucosylation reaction conditions, it was found out that benzyl alcohol is a non-competitive inhibitor of alpha-glucosidase's hydrolytic activity (K-i = 18 mM, toward maltose). Due to its interesting ability to be glycosylated by the enzyme and to inhibit its hydrolytic activity, we proposed a plausible mechanism for the phenolic alpha-glucosydase inhibitor's binding, since the mechanism of inhibition has not yet been elucidated. (C) 2013 Elsevier Ltd. All rights reserved.
PB  - Elsevier Sci Ltd, Oxford
T2  - Carbohydrate Research
T1  - Dual effect of benzyl alcohol on alpha-glucosidase activity: efficient substrate for high yield transglucosylation and non-competitive inhibitor of its hydrolytic activity
VL  - 387
SP  - 14
EP  - 18
DO  - 10.1016/j.carres.2013.08.028
ER  - 

@article{
author = "Pavlović, Marija and Dimitrijević, Aleksandra and Bezbradica, Dejan and Milosavić, Nenad and Gavrović-Jankulović, Marija and Šegan, Dejan M. and Veličković, Dušan",
year = "2014",
abstract = "Benzyl alcohol, a potent anesthetic and bacteriostatic, can be efficiently glucosylated by alpha-glucosidase from Saccharomyces cerevisiae to produce benzyl alcohol alpha-glucoside with a 75% yield. However, while studying the transglucosylation reaction conditions, it was found out that benzyl alcohol is a non-competitive inhibitor of alpha-glucosidase's hydrolytic activity (K-i = 18 mM, toward maltose). Due to its interesting ability to be glycosylated by the enzyme and to inhibit its hydrolytic activity, we proposed a plausible mechanism for the phenolic alpha-glucosydase inhibitor's binding, since the mechanism of inhibition has not yet been elucidated. (C) 2013 Elsevier Ltd. All rights reserved.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Carbohydrate Research",
title = "Dual effect of benzyl alcohol on alpha-glucosidase activity: efficient substrate for high yield transglucosylation and non-competitive inhibitor of its hydrolytic activity",
volume = "387",
pages = "14-18",
doi = "10.1016/j.carres.2013.08.028"
}

Pavlović, M., Dimitrijević, A., Bezbradica, D., Milosavić, N., Gavrović-Jankulović, M., Šegan, D. M.,& Veličković, D.. (2014). Dual effect of benzyl alcohol on alpha-glucosidase activity: efficient substrate for high yield transglucosylation and non-competitive inhibitor of its hydrolytic activity. in Carbohydrate Research
Elsevier Sci Ltd, Oxford., 387, 14-18.
https://doi.org/10.1016/j.carres.2013.08.028

Pavlović M, Dimitrijević A, Bezbradica D, Milosavić N, Gavrović-Jankulović M, Šegan DM, Veličković D. Dual effect of benzyl alcohol on alpha-glucosidase activity: efficient substrate for high yield transglucosylation and non-competitive inhibitor of its hydrolytic activity. in Carbohydrate Research. 2014;387:14-18.
doi:10.1016/j.carres.2013.08.028 .

Pavlović, Marija, Dimitrijević, Aleksandra, Bezbradica, Dejan, Milosavić, Nenad, Gavrović-Jankulović, Marija, Šegan, Dejan M., Veličković, Dušan, "Dual effect of benzyl alcohol on alpha-glucosidase activity: efficient substrate for high yield transglucosylation and non-competitive inhibitor of its hydrolytic activity" in Carbohydrate Research, 387 (2014):14-18,
https://doi.org/10.1016/j.carres.2013.08.028 . .

TY  - JOUR
AU  - Šegan, Dejan M.
AU  - Vukicevic, Rastko D.
AU  - Šegan, Sandra B.
AU  - Šojić, Nešo
AU  - Buriez, Olivier
AU  - Manojlović, Dragan D.
PY  - 2011
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1222
AB  - Cyclic voltammetry and ultramicroelectrodes were used to investigate the kinetic aspects of the electrochemical bromination of 3,4,6-tri-O-acetyl-D-glucal (1) in acetonitrile (AN), dichloromethane (DCM), and dimethylsulfoxide (DMSO). Qualitative and quantitative results, determined notably from the kinetic parameter [glucal]/nu representing the competition between glucal concentration and time, clearly showed that glucal bromination depended on the nature of both the solvent and the in situ electrogenerated reactive brominated species (Br-2 or Br-3(-)) obtained from the oxidation of a bromide salt. It was especially shown that Br-2 reacted more rapidly than Br-3(-) towards (1). On the other hand, the reactivity of both brominated species appeared to follow the solvent polarity order since the highest reactivity was obtained in DMSO whereas the lowest one was found in DCM. (C) 2011 Elsevier Ltd. All rights reserved.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Electrochimica Acta
T1  - Kinetic investigations of the electrochemical bromination of peracetylated D-glucal in organic solvents
VL  - 56
IS  - 27
SP  - 9968
EP  - 9972
DO  - 10.1016/j.electacta.2011.08.085
ER  - 

@article{
author = "Šegan, Dejan M. and Vukicevic, Rastko D. and Šegan, Sandra B. and Šojić, Nešo and Buriez, Olivier and Manojlović, Dragan D.",
year = "2011",
abstract = "Cyclic voltammetry and ultramicroelectrodes were used to investigate the kinetic aspects of the electrochemical bromination of 3,4,6-tri-O-acetyl-D-glucal (1) in acetonitrile (AN), dichloromethane (DCM), and dimethylsulfoxide (DMSO). Qualitative and quantitative results, determined notably from the kinetic parameter [glucal]/nu representing the competition between glucal concentration and time, clearly showed that glucal bromination depended on the nature of both the solvent and the in situ electrogenerated reactive brominated species (Br-2 or Br-3(-)) obtained from the oxidation of a bromide salt. It was especially shown that Br-2 reacted more rapidly than Br-3(-) towards (1). On the other hand, the reactivity of both brominated species appeared to follow the solvent polarity order since the highest reactivity was obtained in DMSO whereas the lowest one was found in DCM. (C) 2011 Elsevier Ltd. All rights reserved.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Electrochimica Acta",
title = "Kinetic investigations of the electrochemical bromination of peracetylated D-glucal in organic solvents",
volume = "56",
number = "27",
pages = "9968-9972",
doi = "10.1016/j.electacta.2011.08.085"
}

Šegan, D. M., Vukicevic, R. D., Šegan, S. B., Šojić, N., Buriez, O.,& Manojlović, D. D.. (2011). Kinetic investigations of the electrochemical bromination of peracetylated D-glucal in organic solvents. in Electrochimica Acta
Pergamon-Elsevier Science Ltd, Oxford., 56(27), 9968-9972.
https://doi.org/10.1016/j.electacta.2011.08.085

Šegan DM, Vukicevic RD, Šegan SB, Šojić N, Buriez O, Manojlović DD. Kinetic investigations of the electrochemical bromination of peracetylated D-glucal in organic solvents. in Electrochimica Acta. 2011;56(27):9968-9972.
doi:10.1016/j.electacta.2011.08.085 .

Šegan, Dejan M., Vukicevic, Rastko D., Šegan, Sandra B., Šojić, Nešo, Buriez, Olivier, Manojlović, Dragan D., "Kinetic investigations of the electrochemical bromination of peracetylated D-glucal in organic solvents" in Electrochimica Acta, 56, no. 27 (2011):9968-9972,
https://doi.org/10.1016/j.electacta.2011.08.085 . .

TY  - JOUR
AU  - Ratkovic, Zoran
AU  - Novaković, Slađana B.
AU  - Bogdanović, Goran A.
AU  - Šegan, Dejan M.
AU  - Vukicevic, Rastko D.
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1098
AB  - The one-pot synthesis of seven new (2-alkylthiobenzoyl)ferrocenes has been achieved by Friedel-Crafts acylation of ferrocene with acid chlorides generated in situ from the corresponding carboxylic acids and phosphorous trichloride. The obtained compounds were characterized by spectroscopic data (UV, IR, (1)H and (13)C NMR), whereas their electrochemical properties have been investigated by cyclic voltammetry. The single-crystal X-ray structure determinations for three of them are also reported. Each of the three derivatives exhibits the intramolecular C-H center dot center dot center dot O interaction which involves the donor from the cyclopentadienyl (Cp) ring and the carbonyl oxygen as acceptor. This interaction favors the coplanar arrangement of the two moieties. The angles between the vectors coinciding the C-O bonds and the corresponding Cp planes are all below 6.4 degrees. Conventional hydrogen bonds do not exist in any of the three crystal structures but some weak intermolecular interactions of the C-H center dot center dot center dot, C-H center dot center dot center dot S and C-H center dot center dot center dot pi types have been found and analyzed in detail. Different geometrical parameters for these crystal structures as well as for 22 similar ones extracted from Cambridge Structural Database (CSD) have been compared and analyzed. (C) 2010 Elsevier Ltd. All rights reserved.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Polyhedron
T1  - Synthesis, spectral characterization and electrochemical properties of (2-alkylthiobenzoyl)ferrocenes. Crystal structures of 2-methylthio, 2-ethylthio and 2-isopropylthio derivatives
VL  - 29
IS  - 11
SP  - 2311
EP  - 2317
DO  - 10.1016/j.poly.2010.04.034
ER  - 

@article{
author = "Ratkovic, Zoran and Novaković, Slađana B. and Bogdanović, Goran A. and Šegan, Dejan M. and Vukicevic, Rastko D.",
year = "2010",
abstract = "The one-pot synthesis of seven new (2-alkylthiobenzoyl)ferrocenes has been achieved by Friedel-Crafts acylation of ferrocene with acid chlorides generated in situ from the corresponding carboxylic acids and phosphorous trichloride. The obtained compounds were characterized by spectroscopic data (UV, IR, (1)H and (13)C NMR), whereas their electrochemical properties have been investigated by cyclic voltammetry. The single-crystal X-ray structure determinations for three of them are also reported. Each of the three derivatives exhibits the intramolecular C-H center dot center dot center dot O interaction which involves the donor from the cyclopentadienyl (Cp) ring and the carbonyl oxygen as acceptor. This interaction favors the coplanar arrangement of the two moieties. The angles between the vectors coinciding the C-O bonds and the corresponding Cp planes are all below 6.4 degrees. Conventional hydrogen bonds do not exist in any of the three crystal structures but some weak intermolecular interactions of the C-H center dot center dot center dot, C-H center dot center dot center dot S and C-H center dot center dot center dot pi types have been found and analyzed in detail. Different geometrical parameters for these crystal structures as well as for 22 similar ones extracted from Cambridge Structural Database (CSD) have been compared and analyzed. (C) 2010 Elsevier Ltd. All rights reserved.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Polyhedron",
title = "Synthesis, spectral characterization and electrochemical properties of (2-alkylthiobenzoyl)ferrocenes. Crystal structures of 2-methylthio, 2-ethylthio and 2-isopropylthio derivatives",
volume = "29",
number = "11",
pages = "2311-2317",
doi = "10.1016/j.poly.2010.04.034"
}

Ratkovic, Z., Novaković, S. B., Bogdanović, G. A., Šegan, D. M.,& Vukicevic, R. D.. (2010). Synthesis, spectral characterization and electrochemical properties of (2-alkylthiobenzoyl)ferrocenes. Crystal structures of 2-methylthio, 2-ethylthio and 2-isopropylthio derivatives. in Polyhedron
Pergamon-Elsevier Science Ltd, Oxford., 29(11), 2311-2317.
https://doi.org/10.1016/j.poly.2010.04.034

Ratkovic Z, Novaković SB, Bogdanović GA, Šegan DM, Vukicevic RD. Synthesis, spectral characterization and electrochemical properties of (2-alkylthiobenzoyl)ferrocenes. Crystal structures of 2-methylthio, 2-ethylthio and 2-isopropylthio derivatives. in Polyhedron. 2010;29(11):2311-2317.
doi:10.1016/j.poly.2010.04.034 .

Ratkovic, Zoran, Novaković, Slađana B., Bogdanović, Goran A., Šegan, Dejan M., Vukicevic, Rastko D., "Synthesis, spectral characterization and electrochemical properties of (2-alkylthiobenzoyl)ferrocenes. Crystal structures of 2-methylthio, 2-ethylthio and 2-isopropylthio derivatives" in Polyhedron, 29, no. 11 (2010):2311-2317,
https://doi.org/10.1016/j.poly.2010.04.034 . .

TY  - JOUR
AU  - Sredic, Svjetlana
AU  - Davidovic, Milorad
AU  - Spasjevic-de-Bire, Anne
AU  - Mioč, Ubavka B.
AU  - Todorović, Marija B.
AU  - Šegan, Dejan M.
AU  - Jovanović, Dušan
AU  - Polizos, George
AU  - Pissis, Polycarpos
PY  - 2008
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/968
AB  - Our previous experiences with incorporation of polyoxometalates (POMs) ill different substrates have been very successful, because new nanocomposites with better conductive, catalytical and biochemical characteristics have been obtained. The results of intercalation of different mass% of ammonium decavanadate (ADV) in Al-pillared interlayered clays (Al-PILCs) are presented. The Al-PILCs were prepared using natural raw material, bentonite, containing a high percentage of montmorillonite (MM). Synthesis of ADV has been described in a previous paper. The structure of ADV hexahydrate was determined at low temperature, 100 K. A kappa refinement was performed to estimate the atomic charges. A sol-gel procedure was applied to obtain Al-PILCs composite intercalated with ADV hexahydrate (from 2 to 5 mass% of ADV). Structure and morphological properties of the new material, a nanocomposite of Al-PILCs-ADV, were investigated by X-ray powder diffraction (XRPD) and atomic force microscopy (AFM). To understand better how ADV is incorporated in the MM substrate, specific surface areas, pore structures and pore distributions were determined. Electrical and dielectric properties of the new materials were investigated by thermally stimulated depolarization currents (TSDCs) and broadband dielectric relaxation spectroscopy (DRS). The electrical conductivity of the nanocomposite was found to increase, in relation to MM, by intercalating with a small amount of ADV. (C) 2008 Published by Elsevier Ltd.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Journal of Physics and Chemistry of Solids
T1  - Inorganic-inorganic nanocomposite: Surface and conductive properties
VL  - 69
IS  - 8
SP  - 1883
EP  - 1890
DO  - 10.1016/j.jpcs.2007.12.023
ER  - 

@article{
author = "Sredic, Svjetlana and Davidovic, Milorad and Spasjevic-de-Bire, Anne and Mioč, Ubavka B. and Todorović, Marija B. and Šegan, Dejan M. and Jovanović, Dušan and Polizos, George and Pissis, Polycarpos",
year = "2008",
abstract = "Our previous experiences with incorporation of polyoxometalates (POMs) ill different substrates have been very successful, because new nanocomposites with better conductive, catalytical and biochemical characteristics have been obtained. The results of intercalation of different mass% of ammonium decavanadate (ADV) in Al-pillared interlayered clays (Al-PILCs) are presented. The Al-PILCs were prepared using natural raw material, bentonite, containing a high percentage of montmorillonite (MM). Synthesis of ADV has been described in a previous paper. The structure of ADV hexahydrate was determined at low temperature, 100 K. A kappa refinement was performed to estimate the atomic charges. A sol-gel procedure was applied to obtain Al-PILCs composite intercalated with ADV hexahydrate (from 2 to 5 mass% of ADV). Structure and morphological properties of the new material, a nanocomposite of Al-PILCs-ADV, were investigated by X-ray powder diffraction (XRPD) and atomic force microscopy (AFM). To understand better how ADV is incorporated in the MM substrate, specific surface areas, pore structures and pore distributions were determined. Electrical and dielectric properties of the new materials were investigated by thermally stimulated depolarization currents (TSDCs) and broadband dielectric relaxation spectroscopy (DRS). The electrical conductivity of the nanocomposite was found to increase, in relation to MM, by intercalating with a small amount of ADV. (C) 2008 Published by Elsevier Ltd.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Journal of Physics and Chemistry of Solids",
title = "Inorganic-inorganic nanocomposite: Surface and conductive properties",
volume = "69",
number = "8",
pages = "1883-1890",
doi = "10.1016/j.jpcs.2007.12.023"
}

Sredic, S., Davidovic, M., Spasjevic-de-Bire, A., Mioč, U. B., Todorović, M. B., Šegan, D. M., Jovanović, D., Polizos, G.,& Pissis, P.. (2008). Inorganic-inorganic nanocomposite: Surface and conductive properties. in Journal of Physics and Chemistry of Solids
Pergamon-Elsevier Science Ltd, Oxford., 69(8), 1883-1890.
https://doi.org/10.1016/j.jpcs.2007.12.023

Sredic S, Davidovic M, Spasjevic-de-Bire A, Mioč UB, Todorović MB, Šegan DM, Jovanović D, Polizos G, Pissis P. Inorganic-inorganic nanocomposite: Surface and conductive properties. in Journal of Physics and Chemistry of Solids. 2008;69(8):1883-1890.
doi:10.1016/j.jpcs.2007.12.023 .

Sredic, Svjetlana, Davidovic, Milorad, Spasjevic-de-Bire, Anne, Mioč, Ubavka B., Todorović, Marija B., Šegan, Dejan M., Jovanović, Dušan, Polizos, George, Pissis, Polycarpos, "Inorganic-inorganic nanocomposite: Surface and conductive properties" in Journal of Physics and Chemistry of Solids, 69, no. 8 (2008):1883-1890,
https://doi.org/10.1016/j.jpcs.2007.12.023 . .

TY  - JOUR
AU  - Colovic, Marija
AU  - Vukicevic, Mirjana
AU  - Šegan, Dejan M.
AU  - Manojlović, Dragan D.
AU  - Šojić, Nešo
AU  - Somsak, Laszlo
AU  - Vukicevic, Rastko D.
PY  - 2008
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/909
AB  - Bromination of glycals with tribromides formed in situ from bromine and different bromide salts in dichloromethane (DCM) or acetonitrile (AN) was found to give predominantly the products of anti addition of bromine from the C-6 side in high yields. The same selectivity, which was much higher compared to bromination with bromine alone, was achieved in bromination of these substrates by anodic generation of bromine from the same salts.
PB  - Wiley-V C H Verlag Gmbh, Weinheim
T2  - Advanced Synthesis and Catalysis
T1  - Electrochemical bromination of peracetylated glycals
VL  - 350
IS  - 1
SP  - 29
EP  - 34
DO  - 10.1002/adsc.200700310
ER  - 

@article{
author = "Colovic, Marija and Vukicevic, Mirjana and Šegan, Dejan M. and Manojlović, Dragan D. and Šojić, Nešo and Somsak, Laszlo and Vukicevic, Rastko D.",
year = "2008",
abstract = "Bromination of glycals with tribromides formed in situ from bromine and different bromide salts in dichloromethane (DCM) or acetonitrile (AN) was found to give predominantly the products of anti addition of bromine from the C-6 side in high yields. The same selectivity, which was much higher compared to bromination with bromine alone, was achieved in bromination of these substrates by anodic generation of bromine from the same salts.",
publisher = "Wiley-V C H Verlag Gmbh, Weinheim",
journal = "Advanced Synthesis and Catalysis",
title = "Electrochemical bromination of peracetylated glycals",
volume = "350",
number = "1",
pages = "29-34",
doi = "10.1002/adsc.200700310"
}

Colovic, M., Vukicevic, M., Šegan, D. M., Manojlović, D. D., Šojić, N., Somsak, L.,& Vukicevic, R. D.. (2008). Electrochemical bromination of peracetylated glycals. in Advanced Synthesis and Catalysis
Wiley-V C H Verlag Gmbh, Weinheim., 350(1), 29-34.
https://doi.org/10.1002/adsc.200700310

Colovic M, Vukicevic M, Šegan DM, Manojlović DD, Šojić N, Somsak L, Vukicevic RD. Electrochemical bromination of peracetylated glycals. in Advanced Synthesis and Catalysis. 2008;350(1):29-34.
doi:10.1002/adsc.200700310 .

Colovic, Marija, Vukicevic, Mirjana, Šegan, Dejan M., Manojlović, Dragan D., Šojić, Nešo, Somsak, Laszlo, Vukicevic, Rastko D., "Electrochemical bromination of peracetylated glycals" in Advanced Synthesis and Catalysis, 350, no. 1 (2008):29-34,
https://doi.org/10.1002/adsc.200700310 . .

TY  - JOUR
AU  - Simic, Aleksandra
AU  - Manojlović, Dragan D.
AU  - Šegan, Dejan M.
AU  - Todorović, Marija B.
PY  - 2007
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/898
AB  - We have investigated the electrochemical oxidation of a number natural phenolics ( salicylic acid, m-hydroxybenzoic acid, p-hydroxybenzoic acid, protocatechuic acid, o-coumaric acid, m-coumaric acid, p-coumaric acid, caffeic acid, quercetin and rutin) using cyclic voltammetry. The antioxidant properties of these compounds were also studied. A structural analysis of the tested phenolics suggests that multiple OH substitution and conjugation are important determinants of the free radical scavenging activity and electrochemical behavior. Compounds with low oxidation potentials (Epa lower than 0.45) showed antioxidant activity, whereas compounds with high Epa values ( gt  0.45) act as prooxidants.
PB  - Molecular Diversity Preservation Int, Basel
T2  - Molecules
T1  - Electrochemical Behavior and antioxidant and prooxidant activity of natural phenolics
VL  - 12
IS  - 10
SP  - 2327
EP  - 2340
DO  - 10.3390/12102327
ER  - 

@article{
author = "Simic, Aleksandra and Manojlović, Dragan D. and Šegan, Dejan M. and Todorović, Marija B.",
year = "2007",
abstract = "We have investigated the electrochemical oxidation of a number natural phenolics ( salicylic acid, m-hydroxybenzoic acid, p-hydroxybenzoic acid, protocatechuic acid, o-coumaric acid, m-coumaric acid, p-coumaric acid, caffeic acid, quercetin and rutin) using cyclic voltammetry. The antioxidant properties of these compounds were also studied. A structural analysis of the tested phenolics suggests that multiple OH substitution and conjugation are important determinants of the free radical scavenging activity and electrochemical behavior. Compounds with low oxidation potentials (Epa lower than 0.45) showed antioxidant activity, whereas compounds with high Epa values ( gt  0.45) act as prooxidants.",
publisher = "Molecular Diversity Preservation Int, Basel",
journal = "Molecules",
title = "Electrochemical Behavior and antioxidant and prooxidant activity of natural phenolics",
volume = "12",
number = "10",
pages = "2327-2340",
doi = "10.3390/12102327"
}

Simic, A., Manojlović, D. D., Šegan, D. M.,& Todorović, M. B.. (2007). Electrochemical Behavior and antioxidant and prooxidant activity of natural phenolics. in Molecules
Molecular Diversity Preservation Int, Basel., 12(10), 2327-2340.
https://doi.org/10.3390/12102327

Simic A, Manojlović DD, Šegan DM, Todorović MB. Electrochemical Behavior and antioxidant and prooxidant activity of natural phenolics. in Molecules. 2007;12(10):2327-2340.
doi:10.3390/12102327 .

Simic, Aleksandra, Manojlović, Dragan D., Šegan, Dejan M., Todorović, Marija B., "Electrochemical Behavior and antioxidant and prooxidant activity of natural phenolics" in Molecules, 12, no. 10 (2007):2327-2340,
https://doi.org/10.3390/12102327 . .

TY  - JOUR
AU  - Todorović, Marija B.
AU  - Mioč, Ubavka B.
AU  - Holclajtner-Antunović, Ivanka
AU  - Šegan, Dejan M.
PY  - 2005
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/723
AB  - It is known that various polyoxovanadates interact specifically with enzymes, which is the main way of their biochemical activity. Therefore we have synthesized ammonium decavanadate, (NH4)(6)V(10)O(28)(.)6H(2)O. The novel compound was characterized by elemental and thermal analysis, X-ray powder and single crystal diffraction and IR and Raman spectroscopy. Its conductive properties have been studied, too. The spectroscopic analysis has shown the presence of hydrogen bonds of different strengths. In order to improve the biochemical activity of this compound and having in mind the presence of strong hydrogen bonds, we essayed the synthesis of complex of polyoxovanadate with alanine. The obtained product was characterized by the mentioned methods.
PB  - Trans Tech Publications Ltd, Zurich-Uetikon
T2  - Materials Science Forum
T1  - Synthesis and characterization of ammonium Decavanadate (V)
VL  - 494
SP  - 351
EP  - 356
DO  - 10.4028/www.scientific.net/MSF.494.351
ER  - 

@article{
author = "Todorović, Marija B. and Mioč, Ubavka B. and Holclajtner-Antunović, Ivanka and Šegan, Dejan M.",
year = "2005",
abstract = "It is known that various polyoxovanadates interact specifically with enzymes, which is the main way of their biochemical activity. Therefore we have synthesized ammonium decavanadate, (NH4)(6)V(10)O(28)(.)6H(2)O. The novel compound was characterized by elemental and thermal analysis, X-ray powder and single crystal diffraction and IR and Raman spectroscopy. Its conductive properties have been studied, too. The spectroscopic analysis has shown the presence of hydrogen bonds of different strengths. In order to improve the biochemical activity of this compound and having in mind the presence of strong hydrogen bonds, we essayed the synthesis of complex of polyoxovanadate with alanine. The obtained product was characterized by the mentioned methods.",
publisher = "Trans Tech Publications Ltd, Zurich-Uetikon",
journal = "Materials Science Forum",
title = "Synthesis and characterization of ammonium Decavanadate (V)",
volume = "494",
pages = "351-356",
doi = "10.4028/www.scientific.net/MSF.494.351"
}

Todorović, M. B., Mioč, U. B., Holclajtner-Antunović, I.,& Šegan, D. M.. (2005). Synthesis and characterization of ammonium Decavanadate (V). in Materials Science Forum
Trans Tech Publications Ltd, Zurich-Uetikon., 494, 351-356.
https://doi.org/10.4028/www.scientific.net/MSF.494.351

Todorović MB, Mioč UB, Holclajtner-Antunović I, Šegan DM. Synthesis and characterization of ammonium Decavanadate (V). in Materials Science Forum. 2005;494:351-356.
doi:10.4028/www.scientific.net/MSF.494.351 .

Todorović, Marija B., Mioč, Ubavka B., Holclajtner-Antunović, Ivanka, Šegan, Dejan M., "Synthesis and characterization of ammonium Decavanadate (V)" in Materials Science Forum, 494 (2005):351-356,
https://doi.org/10.4028/www.scientific.net/MSF.494.351 . .