TY  - JOUR
AU  - Mančić, Lidija
AU  - Đukić-Vuković, Aleksandra
AU  - Dinić, Ivana
AU  - Nikolić, Marko G.
AU  - Rabasović, Mihailo D.
AU  - Krmpot, Aleksandar J.
AU  - Costa, Antonio M. L. M.
AU  - Marinkovic, Bojan A.
AU  - Mojović, Ljiljana
AU  - Milošević, Olivera B.
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2225
AB  - The emerging up-conversion nanoparticles (UCNPs) offer a wide range of biotechnology applications, from biomarkers and deep tissue imaging, to single molecule tracking and drug delivery. Their successful conjugation to biocompatible agents is crucial for specific molecules recognition and usually requires multiple steps which may lead to low reproducibility. Here, we report a simple and rapid one-step procedure for in situ synthesis of biocompatible amino-functionalized NaYF4:Yb,Er UCNPs that could be used for NIR-driven fluorescence cell labeling. X-ray diffraction showed that UCNPs synthesized through chitosan-assisted solvothermal processing are monophasic and crystallize in a cubic alpha phase. Scanning and transmission electron microscopy revealed that the obtained crystals are spherical in shape with a mean diameter of 120 nm. Photoluminescence spectra indicated weaker green (H-2(11/2), S-4(3/2) - gt  (4)/(15/2)) and stronger red emission (F-4(9/2) - gt  (4)/(15/2)), as a result of enhanced non-radiative (4)/(11/2) - gt  (4)/(13/2) Er3+ relaxation. The presence of chitosan groups at the surface of UCNPs was confirmed by Fourier transform infrared spectroscopy, thermogravimetry and X-ray photoelectron spectroscopy. This provides their enhanced internalization in cells, at low concentration of 10 mu g ml(-1), without suppression of cell viability after 24 h of exposure. Furthermore, upon 980 nm laser irradiation, the amino-functionalized NaYF4:Yb,Er UCNPs were successfully used in vitro for labeling of two human cell types, normal gingival and oral squamous cell carcinoma.
PB  - Royal Soc Chemistry, Cambridge
T2  - RSC Advances
T1  - One-step synthesis of amino-functionalized up-converting NaYF4:Yb,Er nanoparticles for in vitro cell imaging
VL  - 8
IS  - 48
SP  - 27429
EP  - 27437
DO  - 10.1039/c8ra04178d
ER  - 

@article{
author = "Mančić, Lidija and Đukić-Vuković, Aleksandra and Dinić, Ivana and Nikolić, Marko G. and Rabasović, Mihailo D. and Krmpot, Aleksandar J. and Costa, Antonio M. L. M. and Marinkovic, Bojan A. and Mojović, Ljiljana and Milošević, Olivera B.",
year = "2018",
abstract = "The emerging up-conversion nanoparticles (UCNPs) offer a wide range of biotechnology applications, from biomarkers and deep tissue imaging, to single molecule tracking and drug delivery. Their successful conjugation to biocompatible agents is crucial for specific molecules recognition and usually requires multiple steps which may lead to low reproducibility. Here, we report a simple and rapid one-step procedure for in situ synthesis of biocompatible amino-functionalized NaYF4:Yb,Er UCNPs that could be used for NIR-driven fluorescence cell labeling. X-ray diffraction showed that UCNPs synthesized through chitosan-assisted solvothermal processing are monophasic and crystallize in a cubic alpha phase. Scanning and transmission electron microscopy revealed that the obtained crystals are spherical in shape with a mean diameter of 120 nm. Photoluminescence spectra indicated weaker green (H-2(11/2), S-4(3/2) - gt  (4)/(15/2)) and stronger red emission (F-4(9/2) - gt  (4)/(15/2)), as a result of enhanced non-radiative (4)/(11/2) - gt  (4)/(13/2) Er3+ relaxation. The presence of chitosan groups at the surface of UCNPs was confirmed by Fourier transform infrared spectroscopy, thermogravimetry and X-ray photoelectron spectroscopy. This provides their enhanced internalization in cells, at low concentration of 10 mu g ml(-1), without suppression of cell viability after 24 h of exposure. Furthermore, upon 980 nm laser irradiation, the amino-functionalized NaYF4:Yb,Er UCNPs were successfully used in vitro for labeling of two human cell types, normal gingival and oral squamous cell carcinoma.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "RSC Advances",
title = "One-step synthesis of amino-functionalized up-converting NaYF4:Yb,Er nanoparticles for in vitro cell imaging",
volume = "8",
number = "48",
pages = "27429-27437",
doi = "10.1039/c8ra04178d"
}

Mančić, L., Đukić-Vuković, A., Dinić, I., Nikolić, M. G., Rabasović, M. D., Krmpot, A. J., Costa, A. M. L. M., Marinkovic, B. A., Mojović, L.,& Milošević, O. B.. (2018). One-step synthesis of amino-functionalized up-converting NaYF4:Yb,Er nanoparticles for in vitro cell imaging. in RSC Advances
Royal Soc Chemistry, Cambridge., 8(48), 27429-27437.
https://doi.org/10.1039/c8ra04178d

Mančić L, Đukić-Vuković A, Dinić I, Nikolić MG, Rabasović MD, Krmpot AJ, Costa AMLM, Marinkovic BA, Mojović L, Milošević OB. One-step synthesis of amino-functionalized up-converting NaYF4:Yb,Er nanoparticles for in vitro cell imaging. in RSC Advances. 2018;8(48):27429-27437.
doi:10.1039/c8ra04178d .

Mančić, Lidija, Đukić-Vuković, Aleksandra, Dinić, Ivana, Nikolić, Marko G., Rabasović, Mihailo D., Krmpot, Aleksandar J., Costa, Antonio M. L. M., Marinkovic, Bojan A., Mojović, Ljiljana, Milošević, Olivera B., "One-step synthesis of amino-functionalized up-converting NaYF4:Yb,Er nanoparticles for in vitro cell imaging" in RSC Advances, 8, no. 48 (2018):27429-27437,
https://doi.org/10.1039/c8ra04178d . .

TY  - DATA
AU  - Mančić, Lidija
AU  - Đukić-Vuković, Aleksandra
AU  - Dinić, Ivana
AU  - Nikolić, Marko G.
AU  - Rabasović, Mihailo D.
AU  - Krmpot, Aleksandar J.
AU  - Costa, Antonio M. L. M.
AU  - Marinkovic, Bojan A.
AU  - Mojović, Ljiljana
AU  - Milošević, Olivera
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3132
PB  - Royal Soc Chemistry, Cambridge
T2  - RSC Advances
T1  - Supplementary data for the article: Mancic, L.; Djukic-Vukovic, A.; Dinic, I.; Nikolic, M. G.; Rabasovic, M. D.; Krmpot, A. J.; Costa, A. M. L. M.; Marinkovic, B. A.; Mojovic, L.; Milosevic, O. One-Step Synthesis of Amino-Functionalized up-Converting NaYF 4 :Yb,Er Nanoparticles for: In Vitro Cell Imaging. RSC Advances 2018, 8 (48), 27429–27437. https://doi.org/10.1039/c8ra04178d
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3132
ER  - 

@misc{
author = "Mančić, Lidija and Đukić-Vuković, Aleksandra and Dinić, Ivana and Nikolić, Marko G. and Rabasović, Mihailo D. and Krmpot, Aleksandar J. and Costa, Antonio M. L. M. and Marinkovic, Bojan A. and Mojović, Ljiljana and Milošević, Olivera",
year = "2018",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "RSC Advances",
title = "Supplementary data for the article: Mancic, L.; Djukic-Vukovic, A.; Dinic, I.; Nikolic, M. G.; Rabasovic, M. D.; Krmpot, A. J.; Costa, A. M. L. M.; Marinkovic, B. A.; Mojovic, L.; Milosevic, O. One-Step Synthesis of Amino-Functionalized up-Converting NaYF 4 :Yb,Er Nanoparticles for: In Vitro Cell Imaging. RSC Advances 2018, 8 (48), 27429–27437. https://doi.org/10.1039/c8ra04178d",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3132"
}

Mančić, L., Đukić-Vuković, A., Dinić, I., Nikolić, M. G., Rabasović, M. D., Krmpot, A. J., Costa, A. M. L. M., Marinkovic, B. A., Mojović, L.,& Milošević, O.. (2018). Supplementary data for the article: Mancic, L.; Djukic-Vukovic, A.; Dinic, I.; Nikolic, M. G.; Rabasovic, M. D.; Krmpot, A. J.; Costa, A. M. L. M.; Marinkovic, B. A.; Mojovic, L.; Milosevic, O. One-Step Synthesis of Amino-Functionalized up-Converting NaYF 4 :Yb,Er Nanoparticles for: In Vitro Cell Imaging. RSC Advances 2018, 8 (48), 27429–27437. https://doi.org/10.1039/c8ra04178d. in RSC Advances
Royal Soc Chemistry, Cambridge..
https://hdl.handle.net/21.15107/rcub_cherry_3132

Mančić L, Đukić-Vuković A, Dinić I, Nikolić MG, Rabasović MD, Krmpot AJ, Costa AMLM, Marinkovic BA, Mojović L, Milošević O. Supplementary data for the article: Mancic, L.; Djukic-Vukovic, A.; Dinic, I.; Nikolic, M. G.; Rabasovic, M. D.; Krmpot, A. J.; Costa, A. M. L. M.; Marinkovic, B. A.; Mojovic, L.; Milosevic, O. One-Step Synthesis of Amino-Functionalized up-Converting NaYF 4 :Yb,Er Nanoparticles for: In Vitro Cell Imaging. RSC Advances 2018, 8 (48), 27429–27437. https://doi.org/10.1039/c8ra04178d. in RSC Advances. 2018;.
https://hdl.handle.net/21.15107/rcub_cherry_3132 .

Mančić, Lidija, Đukić-Vuković, Aleksandra, Dinić, Ivana, Nikolić, Marko G., Rabasović, Mihailo D., Krmpot, Aleksandar J., Costa, Antonio M. L. M., Marinkovic, Bojan A., Mojović, Ljiljana, Milošević, Olivera, "Supplementary data for the article: Mancic, L.; Djukic-Vukovic, A.; Dinic, I.; Nikolic, M. G.; Rabasovic, M. D.; Krmpot, A. J.; Costa, A. M. L. M.; Marinkovic, B. A.; Mojovic, L.; Milosevic, O. One-Step Synthesis of Amino-Functionalized up-Converting NaYF 4 :Yb,Er Nanoparticles for: In Vitro Cell Imaging. RSC Advances 2018, 8 (48), 27429–27437. https://doi.org/10.1039/c8ra04178d" in RSC Advances (2018),
https://hdl.handle.net/21.15107/rcub_cherry_3132 .

TY  - JOUR
AU  - Dinić, Ivana
AU  - Mančić, Lidija
AU  - Rabanal, Maria Eugenia
AU  - Yamamoto, Kazuhiro
AU  - Ohara, Satoshi
AU  - Tamura, Sayaka
AU  - Koji, Tomita
AU  - Costa, Antonio M. L. M.
AU  - Marinkovic, Bojan A.
AU  - Milošević, Olivera B.
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2424
AB  - In this feature article, we highlight our works on compositional and structural dependence of up converting rare earth (RE) fluorides obtained through ethylenediamine tetraacetic acid (EDTA) assisted hydrothermal synthesis. Various nanostructures were obtained by tuning of experimental conditions, such as precursor's concentration, degree of doping, reaction time and solvent used during synthesis. We correlated in detail the structural, morphological and optical properties of YF3 and NaYF4 compounds co-doped with Yb3+ and Er3+ (introduced in total mol% of 8 and 20). For this purpose, X-ray powder diffraction, scanning and transmission electron microscopy, energy dispersive X-ray and Furrier transform infrared spectroscopy, as well as, the photoluminescence spectra and decay times were recorded and analyzed. The particle size and phase content were found to be dependent on the nucleation rate, which, in turn, was governed by the precursor concentration, degree of doping and solvent type. The transformation from cubic to hexagonal NaYF4:Yb3+/Er3+ phase was found to be sensitive to the reaction time and precursors concentration, while the crystallization of orthorhombic YF3:Yb3+/Er3+ phase is achieved through lowering of dopants concentration or by changing of solvent during hydrothermal treatment. The up-conversion photoluminescence demonstrated morphology and crystal phase dependence and is found to be superior in microcrystalline samples, independent on their phase composition. (C) 2016 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology japan. All rights reserved.
PB  - Elsevier Science Bv, Amsterdam
T2  - Advanced Powder Technology
T1  - Compositional and structural dependence of up-converting rare earth fluorides obtained through EDTA assisted hydro/solvothermal synthesis
VL  - 28
IS  - 1
SP  - 73
EP  - 82
DO  - 10.1016/j.apt.2016.09.021
ER  - 

@article{
author = "Dinić, Ivana and Mančić, Lidija and Rabanal, Maria Eugenia and Yamamoto, Kazuhiro and Ohara, Satoshi and Tamura, Sayaka and Koji, Tomita and Costa, Antonio M. L. M. and Marinkovic, Bojan A. and Milošević, Olivera B.",
year = "2017",
abstract = "In this feature article, we highlight our works on compositional and structural dependence of up converting rare earth (RE) fluorides obtained through ethylenediamine tetraacetic acid (EDTA) assisted hydrothermal synthesis. Various nanostructures were obtained by tuning of experimental conditions, such as precursor's concentration, degree of doping, reaction time and solvent used during synthesis. We correlated in detail the structural, morphological and optical properties of YF3 and NaYF4 compounds co-doped with Yb3+ and Er3+ (introduced in total mol% of 8 and 20). For this purpose, X-ray powder diffraction, scanning and transmission electron microscopy, energy dispersive X-ray and Furrier transform infrared spectroscopy, as well as, the photoluminescence spectra and decay times were recorded and analyzed. The particle size and phase content were found to be dependent on the nucleation rate, which, in turn, was governed by the precursor concentration, degree of doping and solvent type. The transformation from cubic to hexagonal NaYF4:Yb3+/Er3+ phase was found to be sensitive to the reaction time and precursors concentration, while the crystallization of orthorhombic YF3:Yb3+/Er3+ phase is achieved through lowering of dopants concentration or by changing of solvent during hydrothermal treatment. The up-conversion photoluminescence demonstrated morphology and crystal phase dependence and is found to be superior in microcrystalline samples, independent on their phase composition. (C) 2016 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology japan. All rights reserved.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Advanced Powder Technology",
title = "Compositional and structural dependence of up-converting rare earth fluorides obtained through EDTA assisted hydro/solvothermal synthesis",
volume = "28",
number = "1",
pages = "73-82",
doi = "10.1016/j.apt.2016.09.021"
}

Dinić, I., Mančić, L., Rabanal, M. E., Yamamoto, K., Ohara, S., Tamura, S., Koji, T., Costa, A. M. L. M., Marinkovic, B. A.,& Milošević, O. B.. (2017). Compositional and structural dependence of up-converting rare earth fluorides obtained through EDTA assisted hydro/solvothermal synthesis. in Advanced Powder Technology
Elsevier Science Bv, Amsterdam., 28(1), 73-82.
https://doi.org/10.1016/j.apt.2016.09.021

Dinić I, Mančić L, Rabanal ME, Yamamoto K, Ohara S, Tamura S, Koji T, Costa AMLM, Marinkovic BA, Milošević OB. Compositional and structural dependence of up-converting rare earth fluorides obtained through EDTA assisted hydro/solvothermal synthesis. in Advanced Powder Technology. 2017;28(1):73-82.
doi:10.1016/j.apt.2016.09.021 .

Dinić, Ivana, Mančić, Lidija, Rabanal, Maria Eugenia, Yamamoto, Kazuhiro, Ohara, Satoshi, Tamura, Sayaka, Koji, Tomita, Costa, Antonio M. L. M., Marinkovic, Bojan A., Milošević, Olivera B., "Compositional and structural dependence of up-converting rare earth fluorides obtained through EDTA assisted hydro/solvothermal synthesis" in Advanced Powder Technology, 28, no. 1 (2017):73-82,
https://doi.org/10.1016/j.apt.2016.09.021 . .