Anđelković, Boban D.

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Authority KeyName Variants
1148c51a-36b6-4288-b339-513d763cbb94
  • Anđelković, Boban D. (32)
  • Anđelković, Boban (3)
Projects
Natural products of wild, cultivated and edible plants: structure and bioactivity determination Allergens, antibodies, enzymes and small physiologically important molecules: design, structure, function and relevance
Reinforcement of the Faculty of Chemistry, University of Belgrade, towards becoming a Center of Excellence in the region of WB for Molecular Biotechnology and Food research Ontogenetic characterization of phylogenetic biodiversity
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200026 (University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM) Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200168 (University of Belgrade, Faculty of Chemistry)
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200288 (Innovation Center of the Faculty of Chemistry) Serbian Academy of Sciences and Arts (01-2019-F65)
Agencia Nacional de Promocion Científica y Tecnologica (PICT 2015-1620 to MCNS), CONICET (PUE INFIVE), CICPBA, UNLP DOC fellowship of the Austrian Academy of Sciences, at the Institute of Zoology, University of Graz [23811]
The synthesis of aminoquinoline-based antimalarials and botulinum neurotoxin A inhibitors Directed synthesis, structure and properties of multifunctional materials
Micromorphological, phytochemical and molecular investigations of plants - systematic, ecological and applicative aspects Microbial diversity study and characterization of beneficial environmental microorganisms
Preclinical investigation of bioactive substances Simultaneous Bioremediation and Soilification of Degraded Areas to Preserve Natural Resources of Biologically Active Substances, and Development and Production of Biomaterials and Dietetic Products
Japan International Cooperation Agency (JICA) (grassroot project “Capacity building for analysis and reduction measures of persistent organic pollutants in Serbia”) National Institute of Allergy and Infectious Diseases (U.S.) [5-U01AI082051-02, R33-AI101387]
Serbian Academy of Sciences and Arts University of Graz
U.S. Defense Threat Reduction Agency/Joint Science and Technology Office Mechanistic studies of the reactions of transition metal ion complexes with biologically relevant molecules
Studying climate change and its influence on environment: impacts, adaptation and mitigation Geography of Serbia
Ministry of Education, Science and Technological Development of the Republic of Serbia

Author's Bibliography

Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines

Nikolić, Andrea; Stanić, Jelena; Zlatar, Matija; Gruden, Maja; Anđelković, Boban; Selaković, Života; Ajdačić, Vladimir; Opsenica, Igor

(American Chemical Society (ACS), 2021)

TY  - JOUR
AU  - Nikolić, Andrea
AU  - Stanić, Jelena
AU  - Zlatar, Matija
AU  - Gruden, Maja
AU  - Anđelković, Boban
AU  - Selaković, Života
AU  - Ajdačić, Vladimir
AU  - Opsenica, Igor
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4358
AB  - The Pd-catalyzed N-arylation method for the synthesis of eighteen N,1-diaryl-1H-tetrazol-5-amine derivatives is reported. By running the reactions at 35 °C, compounds were isolated as single isomers since the undesired Dimroth rearrangement was completely suppressed. Furthermore, the Dimroth rearrangement of N,1-diaryl-1H-tetrazol-5-amines was rationalized by conducting comprehensive experiments and NMR analysis as well as density functional theory (DFT) calculations of thermodynamic stability of the compounds. It was established that the Dimroth rearrangement is thermodynamically controlled, and the equilibrium of the reaction is determined by the stability of the corresponding isomers. The mechanism was investigated by additional DFT calculations, and the opening of the tetrazole ring was shown to be the rate-determining step. By maneuvering Pd-catalyzed N-arylation and the subsequent Dimroth rearrangement, two more N,1-diaryl-1H-tetrazol-5-amine derivatives were acquired, which otherwise cannot be synthesized by employing the C–N cross-coupling reaction.
PB  - American Chemical Society (ACS)
T2  - The Journal of Organic Chemistry
T1  - Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines
VL  - 86
IS  - 6
SP  - 4794
EP  - 4803
DO  - 10.1021/acs.joc.1c00282
ER  - 
@article{
author = "Nikolić, Andrea and Stanić, Jelena and Zlatar, Matija and Gruden, Maja and Anđelković, Boban and Selaković, Života and Ajdačić, Vladimir and Opsenica, Igor",
year = "2021",
abstract = "The Pd-catalyzed N-arylation method for the synthesis of eighteen N,1-diaryl-1H-tetrazol-5-amine derivatives is reported. By running the reactions at 35 °C, compounds were isolated as single isomers since the undesired Dimroth rearrangement was completely suppressed. Furthermore, the Dimroth rearrangement of N,1-diaryl-1H-tetrazol-5-amines was rationalized by conducting comprehensive experiments and NMR analysis as well as density functional theory (DFT) calculations of thermodynamic stability of the compounds. It was established that the Dimroth rearrangement is thermodynamically controlled, and the equilibrium of the reaction is determined by the stability of the corresponding isomers. The mechanism was investigated by additional DFT calculations, and the opening of the tetrazole ring was shown to be the rate-determining step. By maneuvering Pd-catalyzed N-arylation and the subsequent Dimroth rearrangement, two more N,1-diaryl-1H-tetrazol-5-amine derivatives were acquired, which otherwise cannot be synthesized by employing the C–N cross-coupling reaction.",
publisher = "American Chemical Society (ACS)",
journal = "The Journal of Organic Chemistry",
title = "Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines",
volume = "86",
number = "6",
pages = "4794-4803",
doi = "10.1021/acs.joc.1c00282"
}
Nikolić, A., Stanić, J., Zlatar, M., Gruden, M., Anđelković, B., Selaković, Ž., Ajdačić, V.,& Opsenica, I.. (2021). Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines. in The Journal of Organic Chemistry
American Chemical Society (ACS)., 86(6), 4794-4803.
https://doi.org/10.1021/acs.joc.1c00282
Nikolić A, Stanić J, Zlatar M, Gruden M, Anđelković B, Selaković Ž, Ajdačić V, Opsenica I. Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines. in The Journal of Organic Chemistry. 2021;86(6):4794-4803.
doi:10.1021/acs.joc.1c00282 .
Nikolić, Andrea, Stanić, Jelena, Zlatar, Matija, Gruden, Maja, Anđelković, Boban, Selaković, Života, Ajdačić, Vladimir, Opsenica, Igor, "Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines" in The Journal of Organic Chemistry, 86, no. 6 (2021):4794-4803,
https://doi.org/10.1021/acs.joc.1c00282 . .
9
1
1

Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines

Nikolić, Andrea; Stanić, Jelena; Zlatar, Matija; Gruden, Maja; Anđelković, Boban; Selaković, Života; Ajdačić, Vladimir; Opsenica, Igor

(American Chemical Society (ACS), 2021)

TY  - JOUR
AU  - Nikolić, Andrea
AU  - Stanić, Jelena
AU  - Zlatar, Matija
AU  - Gruden, Maja
AU  - Anđelković, Boban
AU  - Selaković, Života
AU  - Ajdačić, Vladimir
AU  - Opsenica, Igor
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4359
AB  - The Pd-catalyzed N-arylation method for the synthesis of eighteen N,1-diaryl-1H-tetrazol-5-amine derivatives is reported. By running the reactions at 35 °C, compounds were isolated as single isomers since the undesired Dimroth rearrangement was completely suppressed. Furthermore, the Dimroth rearrangement of N,1-diaryl-1H-tetrazol-5-amines was rationalized by conducting comprehensive experiments and NMR analysis as well as density functional theory (DFT) calculations of thermodynamic stability of the compounds. It was established that the Dimroth rearrangement is thermodynamically controlled, and the equilibrium of the reaction is determined by the stability of the corresponding isomers. The mechanism was investigated by additional DFT calculations, and the opening of the tetrazole ring was shown to be the rate-determining step. By maneuvering Pd-catalyzed N-arylation and the subsequent Dimroth rearrangement, two more N,1-diaryl-1H-tetrazol-5-amine derivatives were acquired, which otherwise cannot be synthesized by employing the C–N cross-coupling reaction.
PB  - American Chemical Society (ACS)
T2  - The Journal of Organic Chemistry
T1  - Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines
VL  - 86
IS  - 6
SP  - 4794
EP  - 4803
DO  - 10.1021/acs.joc.1c00282
ER  - 
@article{
author = "Nikolić, Andrea and Stanić, Jelena and Zlatar, Matija and Gruden, Maja and Anđelković, Boban and Selaković, Života and Ajdačić, Vladimir and Opsenica, Igor",
year = "2021",
abstract = "The Pd-catalyzed N-arylation method for the synthesis of eighteen N,1-diaryl-1H-tetrazol-5-amine derivatives is reported. By running the reactions at 35 °C, compounds were isolated as single isomers since the undesired Dimroth rearrangement was completely suppressed. Furthermore, the Dimroth rearrangement of N,1-diaryl-1H-tetrazol-5-amines was rationalized by conducting comprehensive experiments and NMR analysis as well as density functional theory (DFT) calculations of thermodynamic stability of the compounds. It was established that the Dimroth rearrangement is thermodynamically controlled, and the equilibrium of the reaction is determined by the stability of the corresponding isomers. The mechanism was investigated by additional DFT calculations, and the opening of the tetrazole ring was shown to be the rate-determining step. By maneuvering Pd-catalyzed N-arylation and the subsequent Dimroth rearrangement, two more N,1-diaryl-1H-tetrazol-5-amine derivatives were acquired, which otherwise cannot be synthesized by employing the C–N cross-coupling reaction.",
publisher = "American Chemical Society (ACS)",
journal = "The Journal of Organic Chemistry",
title = "Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines",
volume = "86",
number = "6",
pages = "4794-4803",
doi = "10.1021/acs.joc.1c00282"
}
Nikolić, A., Stanić, J., Zlatar, M., Gruden, M., Anđelković, B., Selaković, Ž., Ajdačić, V.,& Opsenica, I.. (2021). Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines. in The Journal of Organic Chemistry
American Chemical Society (ACS)., 86(6), 4794-4803.
https://doi.org/10.1021/acs.joc.1c00282
Nikolić A, Stanić J, Zlatar M, Gruden M, Anđelković B, Selaković Ž, Ajdačić V, Opsenica I. Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines. in The Journal of Organic Chemistry. 2021;86(6):4794-4803.
doi:10.1021/acs.joc.1c00282 .
Nikolić, Andrea, Stanić, Jelena, Zlatar, Matija, Gruden, Maja, Anđelković, Boban, Selaković, Života, Ajdačić, Vladimir, Opsenica, Igor, "Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines" in The Journal of Organic Chemistry, 86, no. 6 (2021):4794-4803,
https://doi.org/10.1021/acs.joc.1c00282 . .
9
1
1

Supporting information for the article: Nikolić, A., Stanić, J., Zlatar, M., Gruden, M., Anđelković, B., Selaković, Ž., Ajdačić, V.,& Opsenica, I. (2021). Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines. The Journal of Organic Chemistry, American Chemical Society (ACS)., 86(6), 4794-4803. https://doi.org/10.1021/acs.joc.1c00282

Nikolić, Andrea; Stanić, Jelena; Zlatar, Matija; Gruden, Maja; Anđelković, Boban; Selaković, Života; Ajdačić, Vladimir; Opsenica, Igor

(American Chemical Society (ACS), 2021)

TY  - DATA
AU  - Nikolić, Andrea
AU  - Stanić, Jelena
AU  - Zlatar, Matija
AU  - Gruden, Maja
AU  - Anđelković, Boban
AU  - Selaković, Života
AU  - Ajdačić, Vladimir
AU  - Opsenica, Igor
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4360
AB  - Copies of 1H and 13C NMR spectra for the synthesized compounds; Extended computational results, and total electronic energies, number of imaginary frequencies;  Cartesian coordinates of all structures.
PB  - American Chemical Society (ACS)
T2  - The Journal of Organic Chemistry
T1  - Supporting information for the article: Nikolić, A., Stanić, J., Zlatar, M., Gruden, M., Anđelković, B., Selaković, Ž., Ajdačić, V.,& Opsenica, I. (2021). Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines. The Journal of Organic Chemistry, American Chemical Society (ACS)., 86(6), 4794-4803. https://doi.org/10.1021/acs.joc.1c00282
DO  - 10.1021/acs.joc.1c00282.s001
ER  - 
@misc{
author = "Nikolić, Andrea and Stanić, Jelena and Zlatar, Matija and Gruden, Maja and Anđelković, Boban and Selaković, Života and Ajdačić, Vladimir and Opsenica, Igor",
year = "2021",
abstract = "Copies of 1H and 13C NMR spectra for the synthesized compounds; Extended computational results, and total electronic energies, number of imaginary frequencies;  Cartesian coordinates of all structures.",
publisher = "American Chemical Society (ACS)",
journal = "The Journal of Organic Chemistry",
title = "Supporting information for the article: Nikolić, A., Stanić, J., Zlatar, M., Gruden, M., Anđelković, B., Selaković, Ž., Ajdačić, V.,& Opsenica, I. (2021). Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines. The Journal of Organic Chemistry, American Chemical Society (ACS)., 86(6), 4794-4803. https://doi.org/10.1021/acs.joc.1c00282",
doi = "10.1021/acs.joc.1c00282.s001"
}
Nikolić, A., Stanić, J., Zlatar, M., Gruden, M., Anđelković, B., Selaković, Ž., Ajdačić, V.,& Opsenica, I.. (2021). Supporting information for the article: Nikolić, A., Stanić, J., Zlatar, M., Gruden, M., Anđelković, B., Selaković, Ž., Ajdačić, V.,& Opsenica, I. (2021). Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines. The Journal of Organic Chemistry, American Chemical Society (ACS)., 86(6), 4794-4803. https://doi.org/10.1021/acs.joc.1c00282. in The Journal of Organic Chemistry
American Chemical Society (ACS)..
https://doi.org/10.1021/acs.joc.1c00282.s001
Nikolić A, Stanić J, Zlatar M, Gruden M, Anđelković B, Selaković Ž, Ajdačić V, Opsenica I. Supporting information for the article: Nikolić, A., Stanić, J., Zlatar, M., Gruden, M., Anđelković, B., Selaković, Ž., Ajdačić, V.,& Opsenica, I. (2021). Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines. The Journal of Organic Chemistry, American Chemical Society (ACS)., 86(6), 4794-4803. https://doi.org/10.1021/acs.joc.1c00282. in The Journal of Organic Chemistry. 2021;.
doi:10.1021/acs.joc.1c00282.s001 .
Nikolić, Andrea, Stanić, Jelena, Zlatar, Matija, Gruden, Maja, Anđelković, Boban, Selaković, Života, Ajdačić, Vladimir, Opsenica, Igor, "Supporting information for the article: Nikolić, A., Stanić, J., Zlatar, M., Gruden, M., Anđelković, B., Selaković, Ž., Ajdačić, V.,& Opsenica, I. (2021). Controlling Pd-Catalyzed N-Arylation and Dimroth Rearrangement in the Synthesis of N,1-Diaryl-1H-tetrazol-5-amines. The Journal of Organic Chemistry, American Chemical Society (ACS)., 86(6), 4794-4803. https://doi.org/10.1021/acs.joc.1c00282" in The Journal of Organic Chemistry (2021),
https://doi.org/10.1021/acs.joc.1c00282.s001 . .

Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.)

Kokalj, Doris; Gođevac, Dejan; Anđelković, Boban D.; Cigić, Blaž; Zlatić, Emil; Hribar, Janez; Vidrih, Rajko

(International Society for Horticultural Science, 2019)

TY  - CONF
AU  - Kokalj, Doris
AU  - Gođevac, Dejan
AU  - Anđelković, Boban D.
AU  - Cigić, Blaž
AU  - Zlatić, Emil
AU  - Hribar, Janez
AU  - Vidrih, Rajko
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3736
AB  - A metabolomics approach based on nuclear magnetic resonance (NMR) spectroscopy, a rapid and simple technique, was used for the assessment of chemical changes of 'Van' sweet cherries during their storage. This approach affords a holistic analysis since NMR spectroscopy allows the simultaneous detection of diverse groups of secondary and primary metabolites, and reflects the real molar levels of the metabolites. Additionally, color parameters L∗, a∗ and b∗, total phenolic content (TPC), total flavonoid content (TFC), anthocyanidins and total antioxidant potential (AOP) were measured. After harvest, cherries were stored at 1°C and sampling was done after 0, 2, 4, 7 and 10 days. Cherry skin was removed, freeze dried and stored at -80°C till analyses. For NMR analyses, freeze dried cherry skins have been extracted with methanol-d4/trifluoroacetic acid-d solvent mixture. For other analyses, samples were extracted in 70% ethanol with 1% of formic acid. The 1D and 2D NMR spectral analysis confirmed that sugars (glucose, fructose, sucrose), organic acids (malic and citric acid), and phenolic compounds (neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside) are the main compounds in the cherry skin extracts. The 1H NMR spectral data have been subjected to multivariate analysis. Orthogonal projections to latent structures (OPLS) were applied to correlate the NMR data with the storage time. The changes in chemical composition among the samples with different storage time were clearly visible on the score plot. According to the goodness of fit of the model (R 2 =0.954), and its predictive ability (Q 2 =0.634), cherry skin extracts were well-correlated with the storage time. A positive correlation of the signals corresponding to glucose, neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside with the storage time of cherries has been observed on the loading plot. According to the loading plot, the increase in the content of glucose, neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside has been correlated with the storage time of cherries. Since polyphenolic compounds were found to correlate well with the storage time, the content of redox active compounds was further assessed with AOP, TPC and TFC. All these parameters were increasing for 7 days after harvest then started to decline slightly. The content of all three anthocyanidins increased 2 days after harvest then remained stable till the end of sampling period.
PB  - International Society for Horticultural Science
C3  - Acta Horticulturae
T1  - Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.)
VL  - 1235
SP  - 483
EP  - 488
DO  - 10.17660/ActaHortic.2019.1235.67
ER  - 
@conference{
author = "Kokalj, Doris and Gođevac, Dejan and Anđelković, Boban D. and Cigić, Blaž and Zlatić, Emil and Hribar, Janez and Vidrih, Rajko",
year = "2019",
abstract = "A metabolomics approach based on nuclear magnetic resonance (NMR) spectroscopy, a rapid and simple technique, was used for the assessment of chemical changes of 'Van' sweet cherries during their storage. This approach affords a holistic analysis since NMR spectroscopy allows the simultaneous detection of diverse groups of secondary and primary metabolites, and reflects the real molar levels of the metabolites. Additionally, color parameters L∗, a∗ and b∗, total phenolic content (TPC), total flavonoid content (TFC), anthocyanidins and total antioxidant potential (AOP) were measured. After harvest, cherries were stored at 1°C and sampling was done after 0, 2, 4, 7 and 10 days. Cherry skin was removed, freeze dried and stored at -80°C till analyses. For NMR analyses, freeze dried cherry skins have been extracted with methanol-d4/trifluoroacetic acid-d solvent mixture. For other analyses, samples were extracted in 70% ethanol with 1% of formic acid. The 1D and 2D NMR spectral analysis confirmed that sugars (glucose, fructose, sucrose), organic acids (malic and citric acid), and phenolic compounds (neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside) are the main compounds in the cherry skin extracts. The 1H NMR spectral data have been subjected to multivariate analysis. Orthogonal projections to latent structures (OPLS) were applied to correlate the NMR data with the storage time. The changes in chemical composition among the samples with different storage time were clearly visible on the score plot. According to the goodness of fit of the model (R 2 =0.954), and its predictive ability (Q 2 =0.634), cherry skin extracts were well-correlated with the storage time. A positive correlation of the signals corresponding to glucose, neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside with the storage time of cherries has been observed on the loading plot. According to the loading plot, the increase in the content of glucose, neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside has been correlated with the storage time of cherries. Since polyphenolic compounds were found to correlate well with the storage time, the content of redox active compounds was further assessed with AOP, TPC and TFC. All these parameters were increasing for 7 days after harvest then started to decline slightly. The content of all three anthocyanidins increased 2 days after harvest then remained stable till the end of sampling period.",
publisher = "International Society for Horticultural Science",
journal = "Acta Horticulturae",
title = "Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.)",
volume = "1235",
pages = "483-488",
doi = "10.17660/ActaHortic.2019.1235.67"
}
Kokalj, D., Gođevac, D., Anđelković, B. D., Cigić, B., Zlatić, E., Hribar, J.,& Vidrih, R.. (2019). Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.). in Acta Horticulturae
International Society for Horticultural Science., 1235, 483-488.
https://doi.org/10.17660/ActaHortic.2019.1235.67
Kokalj D, Gođevac D, Anđelković BD, Cigić B, Zlatić E, Hribar J, Vidrih R. Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.). in Acta Horticulturae. 2019;1235:483-488.
doi:10.17660/ActaHortic.2019.1235.67 .
Kokalj, Doris, Gođevac, Dejan, Anđelković, Boban D., Cigić, Blaž, Zlatić, Emil, Hribar, Janez, Vidrih, Rajko, "Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.)" in Acta Horticulturae, 1235 (2019):483-488,
https://doi.org/10.17660/ActaHortic.2019.1235.67 . .

Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes

Ozek, Gulmira; Yur, Suleyman; Goger, Fatih; Ozek, Temel; Anđelković, Boban D.; Godjevac, Dejan; Sofrenić, Ivana V.; Aneva, Ina; Todorova, Milka; Trendafilova, Antoaneta

(Wiley-VHCA AG, 2019)

TY  - JOUR
AU  - Ozek, Gulmira
AU  - Yur, Suleyman
AU  - Goger, Fatih
AU  - Ozek, Temel
AU  - Anđelković, Boban D.
AU  - Godjevac, Dejan
AU  - Sofrenić, Ivana V.
AU  - Aneva, Ina
AU  - Todorova, Milka
AU  - Trendafilova, Antoaneta
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2922
AB  - Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied for their furanocoumarin content antioxidant potential and acetylcholinesterase and α-amylase inhibitory activities. Quantification of the furanocoumarins was performed by 1 H-NMR. Pimpinellin was found to be the main component in the roots of all studied species. Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum, respectively, while byakangelicol dominated in H. angustisectum and H. ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC 50 0.58 mg/mL and 1.83 mm, respectively). The root extracts of H. verticillatum and H. angustisectum were found to be the most effective against acetylcholinesterase (IC 50 0.30 and 0.34 mg/mL, respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7) towards α-amylase.
PB  - Wiley-VHCA AG
T2  - Chemistry and Biodiversity
T1  - Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes
VL  - 16
IS  - 4
SP  - 1800672
DO  - 10.1002/cbdv.201800672
ER  - 
@article{
author = "Ozek, Gulmira and Yur, Suleyman and Goger, Fatih and Ozek, Temel and Anđelković, Boban D. and Godjevac, Dejan and Sofrenić, Ivana V. and Aneva, Ina and Todorova, Milka and Trendafilova, Antoaneta",
year = "2019",
abstract = "Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied for their furanocoumarin content antioxidant potential and acetylcholinesterase and α-amylase inhibitory activities. Quantification of the furanocoumarins was performed by 1 H-NMR. Pimpinellin was found to be the main component in the roots of all studied species. Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum, respectively, while byakangelicol dominated in H. angustisectum and H. ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC 50 0.58 mg/mL and 1.83 mm, respectively). The root extracts of H. verticillatum and H. angustisectum were found to be the most effective against acetylcholinesterase (IC 50 0.30 and 0.34 mg/mL, respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7) towards α-amylase.",
publisher = "Wiley-VHCA AG",
journal = "Chemistry and Biodiversity",
title = "Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes",
volume = "16",
number = "4",
pages = "1800672",
doi = "10.1002/cbdv.201800672"
}
Ozek, G., Yur, S., Goger, F., Ozek, T., Anđelković, B. D., Godjevac, D., Sofrenić, I. V., Aneva, I., Todorova, M.,& Trendafilova, A.. (2019). Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes. in Chemistry and Biodiversity
Wiley-VHCA AG., 16(4), 1800672.
https://doi.org/10.1002/cbdv.201800672
Ozek G, Yur S, Goger F, Ozek T, Anđelković BD, Godjevac D, Sofrenić IV, Aneva I, Todorova M, Trendafilova A. Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes. in Chemistry and Biodiversity. 2019;16(4):1800672.
doi:10.1002/cbdv.201800672 .
Ozek, Gulmira, Yur, Suleyman, Goger, Fatih, Ozek, Temel, Anđelković, Boban D., Godjevac, Dejan, Sofrenić, Ivana V., Aneva, Ina, Todorova, Milka, Trendafilova, Antoaneta, "Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes" in Chemistry and Biodiversity, 16, no. 4 (2019):1800672,
https://doi.org/10.1002/cbdv.201800672 . .
2
1
2
1

Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes

Ozek, Gulmira; Yur, Suleyman; Goger, Fatih; Ozek, Temel; Anđelković, Boban D.; Godjevac, Dejan; Sofrenić, Ivana V.; Aneva, Ina; Todorova, Milka; Trendafilova, Antoaneta

(Wiley-VHCA AG, 2019)

TY  - JOUR
AU  - Ozek, Gulmira
AU  - Yur, Suleyman
AU  - Goger, Fatih
AU  - Ozek, Temel
AU  - Anđelković, Boban D.
AU  - Godjevac, Dejan
AU  - Sofrenić, Ivana V.
AU  - Aneva, Ina
AU  - Todorova, Milka
AU  - Trendafilova, Antoaneta
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2923
AB  - Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied for their furanocoumarin content antioxidant potential and acetylcholinesterase and α-amylase inhibitory activities. Quantification of the furanocoumarins was performed by 1 H-NMR. Pimpinellin was found to be the main component in the roots of all studied species. Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum, respectively, while byakangelicol dominated in H. angustisectum and H. ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC 50 0.58 mg/mL and 1.83 mm, respectively). The root extracts of H. verticillatum and H. angustisectum were found to be the most effective against acetylcholinesterase (IC 50 0.30 and 0.34 mg/mL, respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7) towards α-amylase.
PB  - Wiley-VHCA AG
T2  - Chemistry and Biodiversity
T1  - Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes
VL  - 16
IS  - 4
SP  - 1800672
DO  - 10.1002/cbdv.201800672
ER  - 
@article{
author = "Ozek, Gulmira and Yur, Suleyman and Goger, Fatih and Ozek, Temel and Anđelković, Boban D. and Godjevac, Dejan and Sofrenić, Ivana V. and Aneva, Ina and Todorova, Milka and Trendafilova, Antoaneta",
year = "2019",
abstract = "Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H. ternatum were studied for their furanocoumarin content antioxidant potential and acetylcholinesterase and α-amylase inhibitory activities. Quantification of the furanocoumarins was performed by 1 H-NMR. Pimpinellin was found to be the main component in the roots of all studied species. Bergapten and imperatorin were the major compounds in the fruits of H. sibiricum and H. verticillatum, respectively, while byakangelicol dominated in H. angustisectum and H. ternatum fruits. The leaf and fruit extracts of H. angustisectum demonstrated the highest DPPH radical scavenging activity and TEAC (IC 50 0.58 mg/mL and 1.83 mm, respectively). The root extracts of H. verticillatum and H. angustisectum were found to be the most effective against acetylcholinesterase (IC 50 0.30 and 0.34 mg/mL, respectively). The studied extracts were not active or demonstrated a weak inhibitory effect (%Inh. up to 29.7) towards α-amylase.",
publisher = "Wiley-VHCA AG",
journal = "Chemistry and Biodiversity",
title = "Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes",
volume = "16",
number = "4",
pages = "1800672",
doi = "10.1002/cbdv.201800672"
}
Ozek, G., Yur, S., Goger, F., Ozek, T., Anđelković, B. D., Godjevac, D., Sofrenić, I. V., Aneva, I., Todorova, M.,& Trendafilova, A.. (2019). Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes. in Chemistry and Biodiversity
Wiley-VHCA AG., 16(4), 1800672.
https://doi.org/10.1002/cbdv.201800672
Ozek G, Yur S, Goger F, Ozek T, Anđelković BD, Godjevac D, Sofrenić IV, Aneva I, Todorova M, Trendafilova A. Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes. in Chemistry and Biodiversity. 2019;16(4):1800672.
doi:10.1002/cbdv.201800672 .
Ozek, Gulmira, Yur, Suleyman, Goger, Fatih, Ozek, Temel, Anđelković, Boban D., Godjevac, Dejan, Sofrenić, Ivana V., Aneva, Ina, Todorova, Milka, Trendafilova, Antoaneta, "Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes" in Chemistry and Biodiversity, 16, no. 4 (2019):1800672,
https://doi.org/10.1002/cbdv.201800672 . .
2
1
2
1

Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata

Novaković, Miroslav M.; Bukvicki, Danka; Anđelković, Boban D.; Ilić-Tomić, Tatjana; Veljić, Milan; Tešević, Vele; Asakawa, Yoshinori

(American Chemical Society and American Society of Pharmacognosy, 2019)

TY  - JOUR
AU  - Novaković, Miroslav M.
AU  - Bukvicki, Danka
AU  - Anđelković, Boban D.
AU  - Ilić-Tomić, Tatjana
AU  - Veljić, Milan
AU  - Tešević, Vele
AU  - Asakawa, Yoshinori
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3096
AB  - Seven new bisbibenzyls (1-7) were isolated from the methanol extract of the liverwort Lunularia cruciata along with one previously known bibenzyl and five known bisbibenzyls. The structures of compounds 1-7 were elucidated on the basis of the spectroscopic data. These newly isolated bisbibenzyls may be divided into two groups, the acyclic bisbibenzyls, perrottetins (1-3), and the cyclic analogues, riccardins (4-7). Besides standard perrottetin and riccardin structures (1 and 4, respectively), they contain phenanthrene (3 and 5), dihydrophenanthrene (2), and quinone moieties (6 and 7), rarely found in natural products. The new compounds 3 and 5, as well as the known riccardin G, exhibited cytotoxic activity against the A549 lung cancer cell line with IC 50 values of 5.0, 5.0, and 2.5 μM, respectively.
PB  - American Chemical Society and American Society of Pharmacognosy
T2  - Journal of Natural Products
T1  - Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata
VL  - 82
IS  - 4
SP  - 694
EP  - 701
DO  - 10.1021/acs.jnatprod.8b00390
ER  - 
@article{
author = "Novaković, Miroslav M. and Bukvicki, Danka and Anđelković, Boban D. and Ilić-Tomić, Tatjana and Veljić, Milan and Tešević, Vele and Asakawa, Yoshinori",
year = "2019",
abstract = "Seven new bisbibenzyls (1-7) were isolated from the methanol extract of the liverwort Lunularia cruciata along with one previously known bibenzyl and five known bisbibenzyls. The structures of compounds 1-7 were elucidated on the basis of the spectroscopic data. These newly isolated bisbibenzyls may be divided into two groups, the acyclic bisbibenzyls, perrottetins (1-3), and the cyclic analogues, riccardins (4-7). Besides standard perrottetin and riccardin structures (1 and 4, respectively), they contain phenanthrene (3 and 5), dihydrophenanthrene (2), and quinone moieties (6 and 7), rarely found in natural products. The new compounds 3 and 5, as well as the known riccardin G, exhibited cytotoxic activity against the A549 lung cancer cell line with IC 50 values of 5.0, 5.0, and 2.5 μM, respectively.",
publisher = "American Chemical Society and American Society of Pharmacognosy",
journal = "Journal of Natural Products",
title = "Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata",
volume = "82",
number = "4",
pages = "694-701",
doi = "10.1021/acs.jnatprod.8b00390"
}
Novaković, M. M., Bukvicki, D., Anđelković, B. D., Ilić-Tomić, T., Veljić, M., Tešević, V.,& Asakawa, Y.. (2019). Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata. in Journal of Natural Products
American Chemical Society and American Society of Pharmacognosy., 82(4), 694-701.
https://doi.org/10.1021/acs.jnatprod.8b00390
Novaković MM, Bukvicki D, Anđelković BD, Ilić-Tomić T, Veljić M, Tešević V, Asakawa Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata. in Journal of Natural Products. 2019;82(4):694-701.
doi:10.1021/acs.jnatprod.8b00390 .
Novaković, Miroslav M., Bukvicki, Danka, Anđelković, Boban D., Ilić-Tomić, Tatjana, Veljić, Milan, Tešević, Vele, Asakawa, Yoshinori, "Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata" in Journal of Natural Products, 82, no. 4 (2019):694-701,
https://doi.org/10.1021/acs.jnatprod.8b00390 . .
1
6
5
6

Supplementary data for article: Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390

Novaković, Miroslav M.; Bukvicki, Danka; Anđelković, Boban D.; Ilić-Tomić, Tatjana; Veljić, Milan; Tešević, Vele; Asakawa, Yoshinori

(American Chemical Society and American Society of Pharmacognosy, 2019)

TY  - DATA
AU  - Novaković, Miroslav M.
AU  - Bukvicki, Danka
AU  - Anđelković, Boban D.
AU  - Ilić-Tomić, Tatjana
AU  - Veljić, Milan
AU  - Tešević, Vele
AU  - Asakawa, Yoshinori
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3097
PB  - American Chemical Society and American Society of Pharmacognosy
T2  - Journal of Natural Products
T1  - Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390
ER  - 
@misc{
author = "Novaković, Miroslav M. and Bukvicki, Danka and Anđelković, Boban D. and Ilić-Tomić, Tatjana and Veljić, Milan and Tešević, Vele and Asakawa, Yoshinori",
year = "2019",
publisher = "American Chemical Society and American Society of Pharmacognosy",
journal = "Journal of Natural Products",
title = "Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390"
}
Novaković, M. M., Bukvicki, D., Anđelković, B. D., Ilić-Tomić, T., Veljić, M., Tešević, V.,& Asakawa, Y.. (2019). Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390. in Journal of Natural Products
American Chemical Society and American Society of Pharmacognosy..
Novaković MM, Bukvicki D, Anđelković BD, Ilić-Tomić T, Veljić M, Tešević V, Asakawa Y. Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390. in Journal of Natural Products. 2019;..
Novaković, Miroslav M., Bukvicki, Danka, Anđelković, Boban D., Ilić-Tomić, Tatjana, Veljić, Milan, Tešević, Vele, Asakawa, Yoshinori, "Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390" in Journal of Natural Products (2019).

Fungal transformation and reduction of phytotoxicity of grape pomace waste

Troncozo, María I.; Lješević, Marija; Beškoski, Vladimir; Anđelković, Boban D.; Balatti, Pedro A.; Saparrat, Mario C.N.

(Elsevier, 2019)

TY  - JOUR
AU  - Troncozo, María I.
AU  - Lješević, Marija
AU  - Beškoski, Vladimir
AU  - Anđelković, Boban D.
AU  - Balatti, Pedro A.
AU  - Saparrat, Mario C.N.
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3302
AB  - Grape pomace (GP) from Vitis labrusca, the main byproduct from “American table wine” production, is recalcitrant to degradation, and its accumulation is a serious problem with negative environmental impacts. In this work, transformation of grape pomace using a steam pretreatment followed by incubation of GP during a 90-day period with six different fungi were evaluated. Several fungi tested reduced the phytotoxicity of water-soluble fraction (WSFd) from steam-pretreated GP after 90 days’ incubation to lettuce and tomato seeds. U. botrytis caused the largest effective phytotoxicity reduction of WSFd (used in the concentration range of 10–1.25% p/v) and was the only fungus causing the removal of monoaromatic compounds. Therefore, this procedure with U. botrytis effectively reduces the availability of phytotoxic monoaromatic compounds in GP, which opens a way for the development of guidelines for the management of these wastes and their potential use as organic amendments in agricultural soil.
PB  - Elsevier
T2  - Chemosphere
T1  - Fungal transformation and reduction of phytotoxicity of grape pomace waste
VL  - 237
DO  - 10.1016/j.chemosphere.2019.124458
ER  - 
@article{
author = "Troncozo, María I. and Lješević, Marija and Beškoski, Vladimir and Anđelković, Boban D. and Balatti, Pedro A. and Saparrat, Mario C.N.",
year = "2019",
abstract = "Grape pomace (GP) from Vitis labrusca, the main byproduct from “American table wine” production, is recalcitrant to degradation, and its accumulation is a serious problem with negative environmental impacts. In this work, transformation of grape pomace using a steam pretreatment followed by incubation of GP during a 90-day period with six different fungi were evaluated. Several fungi tested reduced the phytotoxicity of water-soluble fraction (WSFd) from steam-pretreated GP after 90 days’ incubation to lettuce and tomato seeds. U. botrytis caused the largest effective phytotoxicity reduction of WSFd (used in the concentration range of 10–1.25% p/v) and was the only fungus causing the removal of monoaromatic compounds. Therefore, this procedure with U. botrytis effectively reduces the availability of phytotoxic monoaromatic compounds in GP, which opens a way for the development of guidelines for the management of these wastes and their potential use as organic amendments in agricultural soil.",
publisher = "Elsevier",
journal = "Chemosphere",
title = "Fungal transformation and reduction of phytotoxicity of grape pomace waste",
volume = "237",
doi = "10.1016/j.chemosphere.2019.124458"
}
Troncozo, M. I., Lješević, M., Beškoski, V., Anđelković, B. D., Balatti, P. A.,& Saparrat, M. C.N.. (2019). Fungal transformation and reduction of phytotoxicity of grape pomace waste. in Chemosphere
Elsevier., 237.
https://doi.org/10.1016/j.chemosphere.2019.124458
Troncozo MI, Lješević M, Beškoski V, Anđelković BD, Balatti PA, Saparrat MC. Fungal transformation and reduction of phytotoxicity of grape pomace waste. in Chemosphere. 2019;237.
doi:10.1016/j.chemosphere.2019.124458 .
Troncozo, María I., Lješević, Marija, Beškoski, Vladimir, Anđelković, Boban D., Balatti, Pedro A., Saparrat, Mario C.N., "Fungal transformation and reduction of phytotoxicity of grape pomace waste" in Chemosphere, 237 (2019),
https://doi.org/10.1016/j.chemosphere.2019.124458 . .
3
3
3

Fungal transformation and reduction of phytotoxicity of grape pomace waste

Troncozo, María I.; Lješević, Marija; Beškoski, Vladimir; Anđelković, Boban D.; Balatti, Pedro A.; Saparrat, Mario C.N.

(Elsevier, 2019)

TY  - JOUR
AU  - Troncozo, María I.
AU  - Lješević, Marija
AU  - Beškoski, Vladimir
AU  - Anđelković, Boban D.
AU  - Balatti, Pedro A.
AU  - Saparrat, Mario C.N.
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3303
AB  - Grape pomace (GP) from Vitis labrusca, the main byproduct from “American table wine” production, is recalcitrant to degradation, and its accumulation is a serious problem with negative environmental impacts. In this work, transformation of grape pomace using a steam pretreatment followed by incubation of GP during a 90-day period with six different fungi were evaluated. Several fungi tested reduced the phytotoxicity of water-soluble fraction (WSFd) from steam-pretreated GP after 90 days’ incubation to lettuce and tomato seeds. U. botrytis caused the largest effective phytotoxicity reduction of WSFd (used in the concentration range of 10–1.25% p/v) and was the only fungus causing the removal of monoaromatic compounds. Therefore, this procedure with U. botrytis effectively reduces the availability of phytotoxic monoaromatic compounds in GP, which opens a way for the development of guidelines for the management of these wastes and their potential use as organic amendments in agricultural soil.
PB  - Elsevier
T2  - Chemosphere
T1  - Fungal transformation and reduction of phytotoxicity of grape pomace waste
VL  - 237
DO  - 10.1016/j.chemosphere.2019.124458
ER  - 
@article{
author = "Troncozo, María I. and Lješević, Marija and Beškoski, Vladimir and Anđelković, Boban D. and Balatti, Pedro A. and Saparrat, Mario C.N.",
year = "2019",
abstract = "Grape pomace (GP) from Vitis labrusca, the main byproduct from “American table wine” production, is recalcitrant to degradation, and its accumulation is a serious problem with negative environmental impacts. In this work, transformation of grape pomace using a steam pretreatment followed by incubation of GP during a 90-day period with six different fungi were evaluated. Several fungi tested reduced the phytotoxicity of water-soluble fraction (WSFd) from steam-pretreated GP after 90 days’ incubation to lettuce and tomato seeds. U. botrytis caused the largest effective phytotoxicity reduction of WSFd (used in the concentration range of 10–1.25% p/v) and was the only fungus causing the removal of monoaromatic compounds. Therefore, this procedure with U. botrytis effectively reduces the availability of phytotoxic monoaromatic compounds in GP, which opens a way for the development of guidelines for the management of these wastes and their potential use as organic amendments in agricultural soil.",
publisher = "Elsevier",
journal = "Chemosphere",
title = "Fungal transformation and reduction of phytotoxicity of grape pomace waste",
volume = "237",
doi = "10.1016/j.chemosphere.2019.124458"
}
Troncozo, M. I., Lješević, M., Beškoski, V., Anđelković, B. D., Balatti, P. A.,& Saparrat, M. C.N.. (2019). Fungal transformation and reduction of phytotoxicity of grape pomace waste. in Chemosphere
Elsevier., 237.
https://doi.org/10.1016/j.chemosphere.2019.124458
Troncozo MI, Lješević M, Beškoski V, Anđelković BD, Balatti PA, Saparrat MC. Fungal transformation and reduction of phytotoxicity of grape pomace waste. in Chemosphere. 2019;237.
doi:10.1016/j.chemosphere.2019.124458 .
Troncozo, María I., Lješević, Marija, Beškoski, Vladimir, Anđelković, Boban D., Balatti, Pedro A., Saparrat, Mario C.N., "Fungal transformation and reduction of phytotoxicity of grape pomace waste" in Chemosphere, 237 (2019),
https://doi.org/10.1016/j.chemosphere.2019.124458 . .
3
3
3

New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model

Konstantinović, Jelena M.; Kiris, Erkan; Kota, Krishna P.; Kugelman-Tonos, Johanny; Selaković, Milica; Cazares, Lisa H.; Terzić-Jovanović, Nataša; Verbić, Tatjana; Anđelković, Boban D.; Duplantier, Allen J.; Bavari, Sina; Šolaja, Bogdan A.

(Amer Chemical Soc, Washington, 2018)

TY  - JOUR
AU  - Konstantinović, Jelena M.
AU  - Kiris, Erkan
AU  - Kota, Krishna P.
AU  - Kugelman-Tonos, Johanny
AU  - Selaković, Milica
AU  - Cazares, Lisa H.
AU  - Terzić-Jovanović, Nataša
AU  - Verbić, Tatjana
AU  - Anđelković, Boban D.
AU  - Duplantier, Allen J.
AU  - Bavari, Sina
AU  - Šolaja, Bogdan A.
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2099
AB  - The synthesis and inhibitory potencies against botulinum neurotoxin serotype A light chain (BoNT/A LC) using in vitro HPLC based enzymatic assay for various steroidal, benzothiophene, thiophene, and adamantane 4-aminoquinoline derivatives are described. In addition, the compounds were evaluated for the activity against BoNT/A holotoxin in mouse embryonic stem cell derived motor neurons. Steroidal derivative 16 showed remarkable protection (up to 89% of uncleaved SNAP-25) even when administered 30 min postintoxication. This appears to be the first example of LC inhibitors antagonizing BoNT intoxication in mouse embryonic stem cell derived motor neurons (mES-MNs) in a postexposure model. Oral administration of 16 was well tolerated in the mouse up to 600 mg/kg, q.d. Although adequate unbound drug levels were not achieved at this dose, the favorable in vitro ADMET results strongly support further work in this series.
PB  - Amer Chemical Soc, Washington
T2  - Journal of Medicinal Chemistry
T1  - New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model
VL  - 61
IS  - 4
SP  - 1595
EP  - 1608
DO  - 10.1021/acs.jmedchem.7b01710
UR  - Kon_3430
ER  - 
@article{
author = "Konstantinović, Jelena M. and Kiris, Erkan and Kota, Krishna P. and Kugelman-Tonos, Johanny and Selaković, Milica and Cazares, Lisa H. and Terzić-Jovanović, Nataša and Verbić, Tatjana and Anđelković, Boban D. and Duplantier, Allen J. and Bavari, Sina and Šolaja, Bogdan A.",
year = "2018",
abstract = "The synthesis and inhibitory potencies against botulinum neurotoxin serotype A light chain (BoNT/A LC) using in vitro HPLC based enzymatic assay for various steroidal, benzothiophene, thiophene, and adamantane 4-aminoquinoline derivatives are described. In addition, the compounds were evaluated for the activity against BoNT/A holotoxin in mouse embryonic stem cell derived motor neurons. Steroidal derivative 16 showed remarkable protection (up to 89% of uncleaved SNAP-25) even when administered 30 min postintoxication. This appears to be the first example of LC inhibitors antagonizing BoNT intoxication in mouse embryonic stem cell derived motor neurons (mES-MNs) in a postexposure model. Oral administration of 16 was well tolerated in the mouse up to 600 mg/kg, q.d. Although adequate unbound drug levels were not achieved at this dose, the favorable in vitro ADMET results strongly support further work in this series.",
publisher = "Amer Chemical Soc, Washington",
journal = "Journal of Medicinal Chemistry",
title = "New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model",
volume = "61",
number = "4",
pages = "1595-1608",
doi = "10.1021/acs.jmedchem.7b01710",
url = "Kon_3430"
}
Konstantinović, J. M., Kiris, E., Kota, K. P., Kugelman-Tonos, J., Selaković, M., Cazares, L. H., Terzić-Jovanović, N., Verbić, T., Anđelković, B. D., Duplantier, A. J., Bavari, S.,& Šolaja, B. A.. (2018). New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model. in Journal of Medicinal Chemistry
Amer Chemical Soc, Washington., 61(4), 1595-1608.
https://doi.org/10.1021/acs.jmedchem.7b01710
Kon_3430
Konstantinović JM, Kiris E, Kota KP, Kugelman-Tonos J, Selaković M, Cazares LH, Terzić-Jovanović N, Verbić T, Anđelković BD, Duplantier AJ, Bavari S, Šolaja BA. New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model. in Journal of Medicinal Chemistry. 2018;61(4):1595-1608.
doi:10.1021/acs.jmedchem.7b01710
Kon_3430 .
Konstantinović, Jelena M., Kiris, Erkan, Kota, Krishna P., Kugelman-Tonos, Johanny, Selaković, Milica, Cazares, Lisa H., Terzić-Jovanović, Nataša, Verbić, Tatjana, Anđelković, Boban D., Duplantier, Allen J., Bavari, Sina, Šolaja, Bogdan A., "New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model" in Journal of Medicinal Chemistry, 61, no. 4 (2018):1595-1608,
https://doi.org/10.1021/acs.jmedchem.7b01710 .,
Kon_3430 .
3
3
3

Supplementary data for the article: Konstantinović, J.; Kiris, E.; Kota, K. P.; Kugelman-Tonos, J.; Videnović, M.; Cazares, L. H.; Terzić Jovanović, N.; Verbić, T. Ž.; Andjelković, B.; Duplantier, A. J.; et al. New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model. Journal of Medicinal Chemistry 2018, 61 (4), 1595–1608. https://doi.org/10.1021/acs.jmedchem.7b01710

Konstantinović, Jelena M.; Kiris, Erkan; Kota, Krishna P.; Kugelman-Tonos, Johanny; Selaković, Milica; Cazares, Lisa H.; Terzić-Jovanović, Nataša; Verbić, Tatjana; Anđelković, Boban D.; Duplantier, Allen J.; Bavari, Sina; Šolaja, Bogdan A.

(Amer Chemical Soc, Washington, 2018)

TY  - DATA
AU  - Konstantinović, Jelena M.
AU  - Kiris, Erkan
AU  - Kota, Krishna P.
AU  - Kugelman-Tonos, Johanny
AU  - Selaković, Milica
AU  - Cazares, Lisa H.
AU  - Terzić-Jovanović, Nataša
AU  - Verbić, Tatjana
AU  - Anđelković, Boban D.
AU  - Duplantier, Allen J.
AU  - Bavari, Sina
AU  - Šolaja, Bogdan A.
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3039
PB  - Amer Chemical Soc, Washington
T2  - Journal of Medicinal Chemistry
T1  - Supplementary data for the article: Konstantinović, J.; Kiris, E.; Kota, K. P.; Kugelman-Tonos, J.; Videnović, M.; Cazares, L. H.; Terzić Jovanović, N.; Verbić, T. Ž.; Andjelković, B.; Duplantier, A. J.; et al. New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model. Journal of Medicinal Chemistry 2018, 61 (4), 1595–1608. https://doi.org/10.1021/acs.jmedchem.7b01710
UR  - Kon_3430
ER  - 
@misc{
author = "Konstantinović, Jelena M. and Kiris, Erkan and Kota, Krishna P. and Kugelman-Tonos, Johanny and Selaković, Milica and Cazares, Lisa H. and Terzić-Jovanović, Nataša and Verbić, Tatjana and Anđelković, Boban D. and Duplantier, Allen J. and Bavari, Sina and Šolaja, Bogdan A.",
year = "2018",
publisher = "Amer Chemical Soc, Washington",
journal = "Journal of Medicinal Chemistry",
title = "Supplementary data for the article: Konstantinović, J.; Kiris, E.; Kota, K. P.; Kugelman-Tonos, J.; Videnović, M.; Cazares, L. H.; Terzić Jovanović, N.; Verbić, T. Ž.; Andjelković, B.; Duplantier, A. J.; et al. New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model. Journal of Medicinal Chemistry 2018, 61 (4), 1595–1608. https://doi.org/10.1021/acs.jmedchem.7b01710",
url = "Kon_3430"
}
Konstantinović, J. M., Kiris, E., Kota, K. P., Kugelman-Tonos, J., Selaković, M., Cazares, L. H., Terzić-Jovanović, N., Verbić, T., Anđelković, B. D., Duplantier, A. J., Bavari, S.,& Šolaja, B. A.. (2018). Supplementary data for the article: Konstantinović, J.; Kiris, E.; Kota, K. P.; Kugelman-Tonos, J.; Videnović, M.; Cazares, L. H.; Terzić Jovanović, N.; Verbić, T. Ž.; Andjelković, B.; Duplantier, A. J.; et al. New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model. Journal of Medicinal Chemistry 2018, 61 (4), 1595–1608. https://doi.org/10.1021/acs.jmedchem.7b01710. in Journal of Medicinal Chemistry
Amer Chemical Soc, Washington..
Kon_3430
Konstantinović JM, Kiris E, Kota KP, Kugelman-Tonos J, Selaković M, Cazares LH, Terzić-Jovanović N, Verbić T, Anđelković BD, Duplantier AJ, Bavari S, Šolaja BA. Supplementary data for the article: Konstantinović, J.; Kiris, E.; Kota, K. P.; Kugelman-Tonos, J.; Videnović, M.; Cazares, L. H.; Terzić Jovanović, N.; Verbić, T. Ž.; Andjelković, B.; Duplantier, A. J.; et al. New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model. Journal of Medicinal Chemistry 2018, 61 (4), 1595–1608. https://doi.org/10.1021/acs.jmedchem.7b01710. in Journal of Medicinal Chemistry. 2018;.
Kon_3430 .
Konstantinović, Jelena M., Kiris, Erkan, Kota, Krishna P., Kugelman-Tonos, Johanny, Selaković, Milica, Cazares, Lisa H., Terzić-Jovanović, Nataša, Verbić, Tatjana, Anđelković, Boban D., Duplantier, Allen J., Bavari, Sina, Šolaja, Bogdan A., "Supplementary data for the article: Konstantinović, J.; Kiris, E.; Kota, K. P.; Kugelman-Tonos, J.; Videnović, M.; Cazares, L. H.; Terzić Jovanović, N.; Verbić, T. Ž.; Andjelković, B.; Duplantier, A. J.; et al. New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model. Journal of Medicinal Chemistry 2018, 61 (4), 1595–1608. https://doi.org/10.1021/acs.jmedchem.7b01710" in Journal of Medicinal Chemistry (2018),
Kon_3430 .

NMR-based metabolomics study of Amphoricarpos species from Montenegro

Cvetković, Mirjana; Anđelković, Boban D.; Stevanović, Vladimir; Jadranin, Milka; Đorđević, Iris; Tešević, Vele; Milosavljević, Slobodan M.; Gođevac, Dejan

(Elsevier Science Bv, Amsterdam, 2018)

TY  - JOUR
AU  - Cvetković, Mirjana
AU  - Anđelković, Boban D.
AU  - Stevanović, Vladimir
AU  - Jadranin, Milka
AU  - Đorđević, Iris
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan M.
AU  - Gođevac, Dejan
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2148
AB  - The genus Amphoricarpos Vis. is endemic of westpart of Balkan peninsula. In order to get more insight into the ambiguous taxonomy of the genus, the metabolomic study of the Amphoricarpos samples, has been undertaken. The(1)H NMR spectroscopy combined with multivariate data analysis has been applied. OPLS-DA has been shown to be the best method for clear discrimination of these samples based on the metabolites present in the extracts. The main difference between A. autariatus and A. neumayeri has been found to be the presence of characteristic sesquiterpene lactones of guaianolide type named amphoricarpolides. While the main sesquiterpene lactone in A. neumayeri was oxidized in position 2, those present in both subspecies of A. autariatus samples were oxidized in position 9. The use of sesquiterpene lactones as taxonomic characters for differentiating species of the Asteraceae family was reviewed elsewhere. For the differentiation of two subspecies, A. autariatus ssp. autariatus, and A. autariatus ssp. bertisceus, chlorogenic and malic acid have been found to be decisive, but these compounds do not have chemotaxonomic significance. Our results were in accordance with above mentioned classification of Blecic and Mayer but they differentiate from those of the recent genomic study of the genus indicating a single, genetically, morphologically and ecologically variable species, without intraspecific taxa.
PB  - Elsevier Science Bv, Amsterdam
T2  - Phytochemistry Letters
T1  - NMR-based metabolomics study of Amphoricarpos species from Montenegro
VL  - 25
SP  - 1
EP  - 5
DO  - 10.1016/j.phytol.2018.03.013
UR  - Kon_3479
ER  - 
@article{
author = "Cvetković, Mirjana and Anđelković, Boban D. and Stevanović, Vladimir and Jadranin, Milka and Đorđević, Iris and Tešević, Vele and Milosavljević, Slobodan M. and Gođevac, Dejan",
year = "2018",
abstract = "The genus Amphoricarpos Vis. is endemic of westpart of Balkan peninsula. In order to get more insight into the ambiguous taxonomy of the genus, the metabolomic study of the Amphoricarpos samples, has been undertaken. The(1)H NMR spectroscopy combined with multivariate data analysis has been applied. OPLS-DA has been shown to be the best method for clear discrimination of these samples based on the metabolites present in the extracts. The main difference between A. autariatus and A. neumayeri has been found to be the presence of characteristic sesquiterpene lactones of guaianolide type named amphoricarpolides. While the main sesquiterpene lactone in A. neumayeri was oxidized in position 2, those present in both subspecies of A. autariatus samples were oxidized in position 9. The use of sesquiterpene lactones as taxonomic characters for differentiating species of the Asteraceae family was reviewed elsewhere. For the differentiation of two subspecies, A. autariatus ssp. autariatus, and A. autariatus ssp. bertisceus, chlorogenic and malic acid have been found to be decisive, but these compounds do not have chemotaxonomic significance. Our results were in accordance with above mentioned classification of Blecic and Mayer but they differentiate from those of the recent genomic study of the genus indicating a single, genetically, morphologically and ecologically variable species, without intraspecific taxa.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Phytochemistry Letters",
title = "NMR-based metabolomics study of Amphoricarpos species from Montenegro",
volume = "25",
pages = "1-5",
doi = "10.1016/j.phytol.2018.03.013",
url = "Kon_3479"
}
Cvetković, M., Anđelković, B. D., Stevanović, V., Jadranin, M., Đorđević, I., Tešević, V., Milosavljević, S. M.,& Gođevac, D.. (2018). NMR-based metabolomics study of Amphoricarpos species from Montenegro. in Phytochemistry Letters
Elsevier Science Bv, Amsterdam., 25, 1-5.
https://doi.org/10.1016/j.phytol.2018.03.013
Kon_3479
Cvetković M, Anđelković BD, Stevanović V, Jadranin M, Đorđević I, Tešević V, Milosavljević SM, Gođevac D. NMR-based metabolomics study of Amphoricarpos species from Montenegro. in Phytochemistry Letters. 2018;25:1-5.
doi:10.1016/j.phytol.2018.03.013
Kon_3479 .
Cvetković, Mirjana, Anđelković, Boban D., Stevanović, Vladimir, Jadranin, Milka, Đorđević, Iris, Tešević, Vele, Milosavljević, Slobodan M., Gođevac, Dejan, "NMR-based metabolomics study of Amphoricarpos species from Montenegro" in Phytochemistry Letters, 25 (2018):1-5,
https://doi.org/10.1016/j.phytol.2018.03.013 .,
Kon_3479 .
1
1
1

Supplementary material for the article: Cvetković, M.; Anđelković, B.; Stevanović, V.; Jadranin, M.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. NMR-Based Metabolomics Study of Amphoricarpos Species from Montenegro. Phytochemistry Letters 2018, 25, 1–5. https://doi.org/10.1016/j.phytol.2018.03.013

Cvetković, Mirjana; Anđelković, Boban D.; Stevanović, Vladimir; Jadranin, Milka; Đorđević, Iris; Tešević, Vele; Milosavljević, Slobodan M.; Gođevac, Dejan

(Elsevier Science Bv, Amsterdam, 2018)

TY  - DATA
AU  - Cvetković, Mirjana
AU  - Anđelković, Boban D.
AU  - Stevanović, Vladimir
AU  - Jadranin, Milka
AU  - Đorđević, Iris
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan M.
AU  - Gođevac, Dejan
PY  - 2018
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3242
PB  - Elsevier Science Bv, Amsterdam
T2  - Phytochemistry Letters
T1  - Supplementary material for the article: Cvetković, M.; Anđelković, B.; Stevanović, V.; Jadranin, M.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. NMR-Based Metabolomics Study of Amphoricarpos Species from Montenegro. Phytochemistry Letters 2018, 25, 1–5. https://doi.org/10.1016/j.phytol.2018.03.013
ER  - 
@misc{
author = "Cvetković, Mirjana and Anđelković, Boban D. and Stevanović, Vladimir and Jadranin, Milka and Đorđević, Iris and Tešević, Vele and Milosavljević, Slobodan M. and Gođevac, Dejan",
year = "2018",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Phytochemistry Letters",
title = "Supplementary material for the article: Cvetković, M.; Anđelković, B.; Stevanović, V.; Jadranin, M.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. NMR-Based Metabolomics Study of Amphoricarpos Species from Montenegro. Phytochemistry Letters 2018, 25, 1–5. https://doi.org/10.1016/j.phytol.2018.03.013"
}
Cvetković, M., Anđelković, B. D., Stevanović, V., Jadranin, M., Đorđević, I., Tešević, V., Milosavljević, S. M.,& Gođevac, D.. (2018). Supplementary material for the article: Cvetković, M.; Anđelković, B.; Stevanović, V.; Jadranin, M.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. NMR-Based Metabolomics Study of Amphoricarpos Species from Montenegro. Phytochemistry Letters 2018, 25, 1–5. https://doi.org/10.1016/j.phytol.2018.03.013. in Phytochemistry Letters
Elsevier Science Bv, Amsterdam..
Cvetković M, Anđelković BD, Stevanović V, Jadranin M, Đorđević I, Tešević V, Milosavljević SM, Gođevac D. Supplementary material for the article: Cvetković, M.; Anđelković, B.; Stevanović, V.; Jadranin, M.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. NMR-Based Metabolomics Study of Amphoricarpos Species from Montenegro. Phytochemistry Letters 2018, 25, 1–5. https://doi.org/10.1016/j.phytol.2018.03.013. in Phytochemistry Letters. 2018;..
Cvetković, Mirjana, Anđelković, Boban D., Stevanović, Vladimir, Jadranin, Milka, Đorđević, Iris, Tešević, Vele, Milosavljević, Slobodan M., Gođevac, Dejan, "Supplementary material for the article: Cvetković, M.; Anđelković, B.; Stevanović, V.; Jadranin, M.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. NMR-Based Metabolomics Study of Amphoricarpos Species from Montenegro. Phytochemistry Letters 2018, 25, 1–5. https://doi.org/10.1016/j.phytol.2018.03.013" in Phytochemistry Letters (2018).

Metabolomics study of Populus type propolis

Anđelković, Boban D.; Vujisić, Ljubodrag V.; Vučković, Ivan M.; Tešević, Vele; Vajs, Vlatka; Gođevac, Dejan

(Elsevier Science Bv, Amsterdam, 2017)

TY  - JOUR
AU  - Anđelković, Boban D.
AU  - Vujisić, Ljubodrag V.
AU  - Vučković, Ivan M.
AU  - Tešević, Vele
AU  - Vajs, Vlatka
AU  - Gođevac, Dejan
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2386
AB  - Herein, we propose rapid and simple spectroscopic methods to determine the chemical composition of propolis derived from various Populus species using a metabolomics approach. In order to correlate variability in Populus type propolis composition with the altitude of its collection, NMR, IR, and DV spec-troscopy followed by OPLS was conducted. The botanical origin of propolis was established by comparing propolis spectral data to those of buds of various Populus species. An O2PLS method was utilized to integrate two blocks of data. According to OPLS and O2PLS, the major compounds in propolis samples, collected from temperate continental climate above 500 m, were phenolic glycerides originating from P. tremula buds. Flavonoids were predominant in propolis samples collected below 400 m, originating from P. nigra and P.x euramericana buds. Samples collected at 400-500 m were of mixed origin, with variable amounts of all detected metabolites.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Metabolomics study of Populus type propolis
VL  - 135
SP  - 217
EP  - 226
DO  - 10.1016/j.jpba.2016.12.003
UR  - Kon_3202
ER  - 
@article{
author = "Anđelković, Boban D. and Vujisić, Ljubodrag V. and Vučković, Ivan M. and Tešević, Vele and Vajs, Vlatka and Gođevac, Dejan",
year = "2017",
abstract = "Herein, we propose rapid and simple spectroscopic methods to determine the chemical composition of propolis derived from various Populus species using a metabolomics approach. In order to correlate variability in Populus type propolis composition with the altitude of its collection, NMR, IR, and DV spec-troscopy followed by OPLS was conducted. The botanical origin of propolis was established by comparing propolis spectral data to those of buds of various Populus species. An O2PLS method was utilized to integrate two blocks of data. According to OPLS and O2PLS, the major compounds in propolis samples, collected from temperate continental climate above 500 m, were phenolic glycerides originating from P. tremula buds. Flavonoids were predominant in propolis samples collected below 400 m, originating from P. nigra and P.x euramericana buds. Samples collected at 400-500 m were of mixed origin, with variable amounts of all detected metabolites.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Metabolomics study of Populus type propolis",
volume = "135",
pages = "217-226",
doi = "10.1016/j.jpba.2016.12.003",
url = "Kon_3202"
}
Anđelković, B. D., Vujisić, L. V., Vučković, I. M., Tešević, V., Vajs, V.,& Gođevac, D.. (2017). Metabolomics study of Populus type propolis. in Journal of Pharmaceutical and Biomedical Analysis
Elsevier Science Bv, Amsterdam., 135, 217-226.
https://doi.org/10.1016/j.jpba.2016.12.003
Kon_3202
Anđelković BD, Vujisić LV, Vučković IM, Tešević V, Vajs V, Gođevac D. Metabolomics study of Populus type propolis. in Journal of Pharmaceutical and Biomedical Analysis. 2017;135:217-226.
doi:10.1016/j.jpba.2016.12.003
Kon_3202 .
Anđelković, Boban D., Vujisić, Ljubodrag V., Vučković, Ivan M., Tešević, Vele, Vajs, Vlatka, Gođevac, Dejan, "Metabolomics study of Populus type propolis" in Journal of Pharmaceutical and Biomedical Analysis, 135 (2017):217-226,
https://doi.org/10.1016/j.jpba.2016.12.003 .,
Kon_3202 .
1
19
19
19

Примена резултата NMR и FTIR спектроскопских техника у мултиваријантној анализи за класификацију прополиса

Anđelković, Boban D.

(Универзитет у Београду, Хемијски факултет, 2017)

TY  - THES
AU  - Anđelković, Boban D.
PY  - 2017
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=5671
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:17343/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=49973519
UR  - http://nardus.mpn.gov.rs/123456789/9332
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2756
AB  - У овом раду су приказане брзе и једноставне спектроскопске методе заодређивање хемијског састава прополиса типа топола са подручја Србије, Босне иХерцеговине и Бугарске коришћењем метаболомичког приступа. У циљукорелисања разлика у хемијском саставу прополиса топола типа са надморскомвисином са које су узорци прикупљени, коришћени су резултати NMR, IR и UVспектроскопских техника у комбинацији са PCA и OPLS статистичким методама.Ботаничко порекло прополиса је утврђено поређењем спектралних податакаузорака прополиса са спектралним подацима фенолних смола пупољакаразличитих врста топола које расту у близини локација са којих су узорциприкупљени. За корелисање две матрице (табеле) спектралних податакакоришћена је O2PLS метода. На основу примењених статистичких анализа (PCA,OPLS i O2PLS), главне компоненте у узорцима прополиса прикупљеним у регијиумерено-континенталне климе на надморској висини изнад 500 m су ацетилглицерил естри фенолних киселина са пупољака Populus tremula. Флавоноидифенолних смола пупољака врста P. nigra и P. x euramericana су најзаступљенији уузорцима прополиса прикупљеним на надморској висини испод 400 m. Узорциприкупљени на надморској висини између 400 и 500 m садрже све поменутесекундарне метаболите топола у различитим односима.Применом OPLS-DA методе на спектралне податке узорци прополиса типатопола су класификовани у две класе назване Планински прополис типа топола иРавничарски прополис типа топола.Антимикробна активност прикупљених узорака је тестирана на Грам-позитивним бактеријским сојевима Staphylococcus aureus (ATCC 6538),клиничком изолату Bacillus cereus, Micrococcus flavus (ATCC 10240) и Listeriamonocytogenes (NCTC 7973), Грам-негативним бактеријама Pseudomonasaeruginosa (ATCC 27853), Salmonella typhimurium (ATCC 13311), Escherichia coli(ATCC 35210) и хуманом изолату Enterobacter cloacae и на гљиви Fusariumoxysporum. Резултати антимикробних тестова показали су високу антимикробнуактивност прополиса према свим испитиваним микроорганизмима.
AB  - Here we have presented simple, fast and rapid spectroscopic methods fordetermination of the chemical composition of Poplar type propolis from Serbia, Bosniaand Herzegovina and Bulgaria, using metabolomics approach. The main objective wasto correlate variability in Poplar type propolis composition with the altitude of itscollection. This was carried out using NMR, IR, and UV spectroscopy followed by PCAand OPLS methods. The botanical origin of the propolis was established by comparingspectral data of propolis with those of various Populus species growing close to thecollection site. An O2PLS method was utilized to integrate two blocks of data.According to PCA, OPLS and O2PLS, the major compounds in propolis samples,collected from temperate continental climate above 500 m, were phenolic glyceridesoriginating from Populus tremula buds. Flavonoids were predominant in propolissamples collected below 400 m, originating from P. nigra and P. x euramericana buds.Samples collected at 400 – 500 m were of mixed origin with variable amount of alldetected metabolites.Using OPLS-DA method and spectral data, poplar propolis samples wereclassified in two classes named Mountain populus type and Flatland populus type.Antimicrobial activity of propolis samples was tested on Gram-positive bacteriaStaphylococcus aureus (ATCC 6538), clinical isolates of Bacillus cereus, Micrococcusflavus (ATCC 10240) and Listeria monocytogenes (NCTC 7973), Gram-negativebacteria Pseudomonas aeruginosa (ATCC 27853), Salmonella typhimurium (ATCC13311), Escherichia coli (ATCC 35210), and human isolate of Enterobacter cloacae,on fungus Fusarium oxysporum. The results of antimicrobial tests showed strongantimicrobial activity of propolis against all tested microorganisms.
PB  - Универзитет у Београду, Хемијски факултет
T2  - Универзитет у Београду
T1  - Примена резултата NMR и FTIR спектроскопских техника у мултиваријантној анализи за класификацију прополиса
ER  - 
@phdthesis{
author = "Anđelković, Boban D.",
year = "2017",
abstract = "У овом раду су приказане брзе и једноставне спектроскопске методе заодређивање хемијског састава прополиса типа топола са подручја Србије, Босне иХерцеговине и Бугарске коришћењем метаболомичког приступа. У циљукорелисања разлика у хемијском саставу прополиса топола типа са надморскомвисином са које су узорци прикупљени, коришћени су резултати NMR, IR и UVспектроскопских техника у комбинацији са PCA и OPLS статистичким методама.Ботаничко порекло прополиса је утврђено поређењем спектралних податакаузорака прополиса са спектралним подацима фенолних смола пупољакаразличитих врста топола које расту у близини локација са којих су узорциприкупљени. За корелисање две матрице (табеле) спектралних податакакоришћена је O2PLS метода. На основу примењених статистичких анализа (PCA,OPLS i O2PLS), главне компоненте у узорцима прополиса прикупљеним у регијиумерено-континенталне климе на надморској висини изнад 500 m су ацетилглицерил естри фенолних киселина са пупољака Populus tremula. Флавоноидифенолних смола пупољака врста P. nigra и P. x euramericana су најзаступљенији уузорцима прополиса прикупљеним на надморској висини испод 400 m. Узорциприкупљени на надморској висини између 400 и 500 m садрже све поменутесекундарне метаболите топола у различитим односима.Применом OPLS-DA методе на спектралне податке узорци прополиса типатопола су класификовани у две класе назване Планински прополис типа топола иРавничарски прополис типа топола.Антимикробна активност прикупљених узорака је тестирана на Грам-позитивним бактеријским сојевима Staphylococcus aureus (ATCC 6538),клиничком изолату Bacillus cereus, Micrococcus flavus (ATCC 10240) и Listeriamonocytogenes (NCTC 7973), Грам-негативним бактеријама Pseudomonasaeruginosa (ATCC 27853), Salmonella typhimurium (ATCC 13311), Escherichia coli(ATCC 35210) и хуманом изолату Enterobacter cloacae и на гљиви Fusariumoxysporum. Резултати антимикробних тестова показали су високу антимикробнуактивност прополиса према свим испитиваним микроорганизмима., Here we have presented simple, fast and rapid spectroscopic methods fordetermination of the chemical composition of Poplar type propolis from Serbia, Bosniaand Herzegovina and Bulgaria, using metabolomics approach. The main objective wasto correlate variability in Poplar type propolis composition with the altitude of itscollection. This was carried out using NMR, IR, and UV spectroscopy followed by PCAand OPLS methods. The botanical origin of the propolis was established by comparingspectral data of propolis with those of various Populus species growing close to thecollection site. An O2PLS method was utilized to integrate two blocks of data.According to PCA, OPLS and O2PLS, the major compounds in propolis samples,collected from temperate continental climate above 500 m, were phenolic glyceridesoriginating from Populus tremula buds. Flavonoids were predominant in propolissamples collected below 400 m, originating from P. nigra and P. x euramericana buds.Samples collected at 400 – 500 m were of mixed origin with variable amount of alldetected metabolites.Using OPLS-DA method and spectral data, poplar propolis samples wereclassified in two classes named Mountain populus type and Flatland populus type.Antimicrobial activity of propolis samples was tested on Gram-positive bacteriaStaphylococcus aureus (ATCC 6538), clinical isolates of Bacillus cereus, Micrococcusflavus (ATCC 10240) and Listeria monocytogenes (NCTC 7973), Gram-negativebacteria Pseudomonas aeruginosa (ATCC 27853), Salmonella typhimurium (ATCC13311), Escherichia coli (ATCC 35210), and human isolate of Enterobacter cloacae,on fungus Fusarium oxysporum. The results of antimicrobial tests showed strongantimicrobial activity of propolis against all tested microorganisms.",
publisher = "Универзитет у Београду, Хемијски факултет",
journal = "Универзитет у Београду",
title = "Примена резултата NMR и FTIR спектроскопских техника у мултиваријантној анализи за класификацију прополиса"
}
Anđelković, B. D.. (2017). Примена резултата NMR и FTIR спектроскопских техника у мултиваријантној анализи за класификацију прополиса. in Универзитет у Београду
Универзитет у Београду, Хемијски факултет..
Anđelković BD. Примена резултата NMR и FTIR спектроскопских техника у мултиваријантној анализи за класификацију прополиса. in Универзитет у Београду. 2017;..
Anđelković, Boban D., "Примена резултата NMR и FTIR спектроскопских техника у мултиваријантној анализи за класификацију прополиса" in Универзитет у Београду (2017).

Metabolomics study of Populus type propolis

Anđelković, Boban D.; Vujisić, Ljubodrag V.; Vučković, Ivan M.; Tešević, Vele; Vajs, Vlatka; Gođevac, Dejan

(Elsevier Science Bv, Amsterdam, 2017)

TY  - JOUR
AU  - Anđelković, Boban D.
AU  - Vujisić, Ljubodrag V.
AU  - Vučković, Ivan M.
AU  - Tešević, Vele
AU  - Vajs, Vlatka
AU  - Gođevac, Dejan
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3017
AB  - Herein, we propose rapid and simple spectroscopic methods to determine the chemical composition of propolis derived from various Populus species using a metabolomics approach. In order to correlate variability in Populus type propolis composition with the altitude of its collection, NMR, IR, and DV spec-troscopy followed by OPLS was conducted. The botanical origin of propolis was established by comparing propolis spectral data to those of buds of various Populus species. An O2PLS method was utilized to integrate two blocks of data. According to OPLS and O2PLS, the major compounds in propolis samples, collected from temperate continental climate above 500 m, were phenolic glycerides originating from P. tremula buds. Flavonoids were predominant in propolis samples collected below 400 m, originating from P. nigra and P.x euramericana buds. Samples collected at 400-500 m were of mixed origin, with variable amounts of all detected metabolites.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Metabolomics study of Populus type propolis
VL  - 135
SP  - 217
EP  - 226
DO  - 10.1016/j.jpba.2016.12.003
ER  - 
@article{
author = "Anđelković, Boban D. and Vujisić, Ljubodrag V. and Vučković, Ivan M. and Tešević, Vele and Vajs, Vlatka and Gođevac, Dejan",
year = "2017",
abstract = "Herein, we propose rapid and simple spectroscopic methods to determine the chemical composition of propolis derived from various Populus species using a metabolomics approach. In order to correlate variability in Populus type propolis composition with the altitude of its collection, NMR, IR, and DV spec-troscopy followed by OPLS was conducted. The botanical origin of propolis was established by comparing propolis spectral data to those of buds of various Populus species. An O2PLS method was utilized to integrate two blocks of data. According to OPLS and O2PLS, the major compounds in propolis samples, collected from temperate continental climate above 500 m, were phenolic glycerides originating from P. tremula buds. Flavonoids were predominant in propolis samples collected below 400 m, originating from P. nigra and P.x euramericana buds. Samples collected at 400-500 m were of mixed origin, with variable amounts of all detected metabolites.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Metabolomics study of Populus type propolis",
volume = "135",
pages = "217-226",
doi = "10.1016/j.jpba.2016.12.003"
}
Anđelković, B. D., Vujisić, L. V., Vučković, I. M., Tešević, V., Vajs, V.,& Gođevac, D.. (2017). Metabolomics study of Populus type propolis. in Journal of Pharmaceutical and Biomedical Analysis
Elsevier Science Bv, Amsterdam., 135, 217-226.
https://doi.org/10.1016/j.jpba.2016.12.003
Anđelković BD, Vujisić LV, Vučković IM, Tešević V, Vajs V, Gođevac D. Metabolomics study of Populus type propolis. in Journal of Pharmaceutical and Biomedical Analysis. 2017;135:217-226.
doi:10.1016/j.jpba.2016.12.003 .
Anđelković, Boban D., Vujisić, Ljubodrag V., Vučković, Ivan M., Tešević, Vele, Vajs, Vlatka, Gođevac, Dejan, "Metabolomics study of Populus type propolis" in Journal of Pharmaceutical and Biomedical Analysis, 135 (2017):217-226,
https://doi.org/10.1016/j.jpba.2016.12.003 . .
1
19
19
19

Supplementary data for article: Andelkovic, B.; Vujisić, L. V.; Vučković, I. M.; Tešević, V.; Vajs, V.; Godevac, D. Metabolomics Study of Populus Type Propolis. Journal of Pharmaceutical and Biomedical Analysis 2017, 135, 217–226. https://doi.org/10.1016/j.jpba.2016.12.003

Anđelković, Boban D.; Vujisić, Ljubodrag V.; Vučković, Ivan M.; Tešević, Vele; Vajs, Vlatka; Gođevac, Dejan

(Elsevier Science Bv, Amsterdam, 2017)

TY  - DATA
AU  - Anđelković, Boban D.
AU  - Vujisić, Ljubodrag V.
AU  - Vučković, Ivan M.
AU  - Tešević, Vele
AU  - Vajs, Vlatka
AU  - Gođevac, Dejan
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3018
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Supplementary data for article: Andelkovic, B.; Vujisić, L. V.; Vučković, I. M.; Tešević, V.; Vajs, V.; Godevac, D. Metabolomics Study of Populus Type Propolis. Journal of Pharmaceutical and Biomedical Analysis 2017, 135, 217–226. https://doi.org/10.1016/j.jpba.2016.12.003
ER  - 
@misc{
author = "Anđelković, Boban D. and Vujisić, Ljubodrag V. and Vučković, Ivan M. and Tešević, Vele and Vajs, Vlatka and Gođevac, Dejan",
year = "2017",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Supplementary data for article: Andelkovic, B.; Vujisić, L. V.; Vučković, I. M.; Tešević, V.; Vajs, V.; Godevac, D. Metabolomics Study of Populus Type Propolis. Journal of Pharmaceutical and Biomedical Analysis 2017, 135, 217–226. https://doi.org/10.1016/j.jpba.2016.12.003"
}
Anđelković, B. D., Vujisić, L. V., Vučković, I. M., Tešević, V., Vajs, V.,& Gođevac, D.. (2017). Supplementary data for article: Andelkovic, B.; Vujisić, L. V.; Vučković, I. M.; Tešević, V.; Vajs, V.; Godevac, D. Metabolomics Study of Populus Type Propolis. Journal of Pharmaceutical and Biomedical Analysis 2017, 135, 217–226. https://doi.org/10.1016/j.jpba.2016.12.003. in Journal of Pharmaceutical and Biomedical Analysis
Elsevier Science Bv, Amsterdam..
Anđelković BD, Vujisić LV, Vučković IM, Tešević V, Vajs V, Gođevac D. Supplementary data for article: Andelkovic, B.; Vujisić, L. V.; Vučković, I. M.; Tešević, V.; Vajs, V.; Godevac, D. Metabolomics Study of Populus Type Propolis. Journal of Pharmaceutical and Biomedical Analysis 2017, 135, 217–226. https://doi.org/10.1016/j.jpba.2016.12.003. in Journal of Pharmaceutical and Biomedical Analysis. 2017;..
Anđelković, Boban D., Vujisić, Ljubodrag V., Vučković, Ivan M., Tešević, Vele, Vajs, Vlatka, Gođevac, Dejan, "Supplementary data for article: Andelkovic, B.; Vujisić, L. V.; Vučković, I. M.; Tešević, V.; Vajs, V.; Godevac, D. Metabolomics Study of Populus Type Propolis. Journal of Pharmaceutical and Biomedical Analysis 2017, 135, 217–226. https://doi.org/10.1016/j.jpba.2016.12.003" in Journal of Pharmaceutical and Biomedical Analysis (2017).

Chemical Ecology of Cave-Dwelling Millipedes: Defensive Secretions of the Typhloiulini (Diplopoda, Julida, Julidae)

Makarov, Slobodan E.; Bodner, Michaela; Reineke, Doris; Vujisić, Ljubodrag V.; Todosijević, Marina; Antić, Dragan Ž.; Vagalinski, Boyan; Lučić, Luka; Mitić, Bojan M.; Mitov, Plamen; Anđelković, Boban D.; Lucić, Sofija Pavković; Vajs, Vlatka; Tomić, Vladimir T.; Raspotnig, Guenther

(Springer, Dordrecht, 2017)

TY  - JOUR
AU  - Makarov, Slobodan E.
AU  - Bodner, Michaela
AU  - Reineke, Doris
AU  - Vujisić, Ljubodrag V.
AU  - Todosijević, Marina
AU  - Antić, Dragan Ž.
AU  - Vagalinski, Boyan
AU  - Lučić, Luka
AU  - Mitić, Bojan M.
AU  - Mitov, Plamen
AU  - Anđelković, Boban D.
AU  - Lucić, Sofija Pavković
AU  - Vajs, Vlatka
AU  - Tomić, Vladimir T.
AU  - Raspotnig, Guenther
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2450
AB  - Cave animals live under highly constant ecological conditions and in permanent darkness, and many evolutionary adaptations of cave-dwellers have been triggered by their specific environment. A similar "cave effect" leading to pronounced chemical interactions under such conditions may be assumed, but the chemoecology of troglobionts is mostly unknown. We investigated the defensive chemistry of a largely cave-dwelling julid group, the controversial tribe "Typhloiulini", and we included some cave-dwelling and some endogean representatives. While chemical defense in juliform diplopods is known to be highly uniform, and mainly based on methyl- and methoxy-substituted benzoquinones, the defensive secretions of typhloiulines contained ethyl-benzoquinones and related compounds. Interestingly, ethyl-benzoquinones were found in some, but not all cave-dwelling typhloiulines, and some non-cave dwellers also contained these compounds. On the other hand, ethyl-benzoquinones were not detected in troglobiont nor in endogean typhloiuline outgroups. In order to explain the taxonomic pattern of ethyl-benzoquinone occurrence, and to unravel whether a cave-effect triggered ethyl-benzoquinone evolution, we classed the "Typhloiulini" investigated here within a phylogenetic framework of julid taxa, and traced the evolutionary history of ethyl-benzoquinones in typhloiulines in relation to cave-dwelling. The results indicated a cave-independent evolution of ethyl-substituted benzoquinones, indicating the absence of a "cave effect" on the secretions of troglobiont Typhloiulini. Ethyl-benzoquinones probably evolved early in an epi- or endogean ancestor of a clade including several, but not all Typhloiulus (basically comprising a taxonomic entity known as "Typhloiulus sensu stricto") and Serboiulus. Ethyl-benzoquinones are proposed as novel and valuable chemical characters for julid systematics.
PB  - Springer, Dordrecht
T2  - Journal of Chemical Ecology
T1  - Chemical Ecology of Cave-Dwelling Millipedes: Defensive Secretions of the Typhloiulini (Diplopoda, Julida, Julidae)
VL  - 43
IS  - 4
SP  - 317
EP  - 326
DO  - 10.1007/s10886-017-0832-1
UR  - Kon_3266
ER  - 
@article{
author = "Makarov, Slobodan E. and Bodner, Michaela and Reineke, Doris and Vujisić, Ljubodrag V. and Todosijević, Marina and Antić, Dragan Ž. and Vagalinski, Boyan and Lučić, Luka and Mitić, Bojan M. and Mitov, Plamen and Anđelković, Boban D. and Lucić, Sofija Pavković and Vajs, Vlatka and Tomić, Vladimir T. and Raspotnig, Guenther",
year = "2017",
abstract = "Cave animals live under highly constant ecological conditions and in permanent darkness, and many evolutionary adaptations of cave-dwellers have been triggered by their specific environment. A similar "cave effect" leading to pronounced chemical interactions under such conditions may be assumed, but the chemoecology of troglobionts is mostly unknown. We investigated the defensive chemistry of a largely cave-dwelling julid group, the controversial tribe "Typhloiulini", and we included some cave-dwelling and some endogean representatives. While chemical defense in juliform diplopods is known to be highly uniform, and mainly based on methyl- and methoxy-substituted benzoquinones, the defensive secretions of typhloiulines contained ethyl-benzoquinones and related compounds. Interestingly, ethyl-benzoquinones were found in some, but not all cave-dwelling typhloiulines, and some non-cave dwellers also contained these compounds. On the other hand, ethyl-benzoquinones were not detected in troglobiont nor in endogean typhloiuline outgroups. In order to explain the taxonomic pattern of ethyl-benzoquinone occurrence, and to unravel whether a cave-effect triggered ethyl-benzoquinone evolution, we classed the "Typhloiulini" investigated here within a phylogenetic framework of julid taxa, and traced the evolutionary history of ethyl-benzoquinones in typhloiulines in relation to cave-dwelling. The results indicated a cave-independent evolution of ethyl-substituted benzoquinones, indicating the absence of a "cave effect" on the secretions of troglobiont Typhloiulini. Ethyl-benzoquinones probably evolved early in an epi- or endogean ancestor of a clade including several, but not all Typhloiulus (basically comprising a taxonomic entity known as "Typhloiulus sensu stricto") and Serboiulus. Ethyl-benzoquinones are proposed as novel and valuable chemical characters for julid systematics.",
publisher = "Springer, Dordrecht",
journal = "Journal of Chemical Ecology",
title = "Chemical Ecology of Cave-Dwelling Millipedes: Defensive Secretions of the Typhloiulini (Diplopoda, Julida, Julidae)",
volume = "43",
number = "4",
pages = "317-326",
doi = "10.1007/s10886-017-0832-1",
url = "Kon_3266"
}
Makarov, S. E., Bodner, M., Reineke, D., Vujisić, L. V., Todosijević, M., Antić, D. Ž., Vagalinski, B., Lučić, L., Mitić, B. M., Mitov, P., Anđelković, B. D., Lucić, S. P., Vajs, V., Tomić, V. T.,& Raspotnig, G.. (2017). Chemical Ecology of Cave-Dwelling Millipedes: Defensive Secretions of the Typhloiulini (Diplopoda, Julida, Julidae). in Journal of Chemical Ecology
Springer, Dordrecht., 43(4), 317-326.
https://doi.org/10.1007/s10886-017-0832-1
Kon_3266
Makarov SE, Bodner M, Reineke D, Vujisić LV, Todosijević M, Antić DŽ, Vagalinski B, Lučić L, Mitić BM, Mitov P, Anđelković BD, Lucić SP, Vajs V, Tomić VT, Raspotnig G. Chemical Ecology of Cave-Dwelling Millipedes: Defensive Secretions of the Typhloiulini (Diplopoda, Julida, Julidae). in Journal of Chemical Ecology. 2017;43(4):317-326.
doi:10.1007/s10886-017-0832-1
Kon_3266 .
Makarov, Slobodan E., Bodner, Michaela, Reineke, Doris, Vujisić, Ljubodrag V., Todosijević, Marina, Antić, Dragan Ž., Vagalinski, Boyan, Lučić, Luka, Mitić, Bojan M., Mitov, Plamen, Anđelković, Boban D., Lucić, Sofija Pavković, Vajs, Vlatka, Tomić, Vladimir T., Raspotnig, Guenther, "Chemical Ecology of Cave-Dwelling Millipedes: Defensive Secretions of the Typhloiulini (Diplopoda, Julida, Julidae)" in Journal of Chemical Ecology, 43, no. 4 (2017):317-326,
https://doi.org/10.1007/s10886-017-0832-1 .,
Kon_3266 .
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8
8

Supplementary data for article: Makarov, S. E.; Bodner, M.; Reineke, D.; Vujisić, L. V.; Todosijević, M. M.; Antić, D. Ž.; Vagalinski, B.; Lučić, L. R.; Mitić, B. M.; Mitov, P.; et al. Chemical Ecology of Cave-Dwelling Millipedes: Defensive Secretions of the Typhloiulini (Diplopoda, Julida, Julidae). Journal of Chemical Ecology 2017, 43 (4), 317–326. https://doi.org/10.1007/s10886-017-0832-1

Makarov, Slobodan E.; Bodner, Michaela; Reineke, Doris; Vujisić, Ljubodrag V.; Todosijević, Marina; Antić, Dragan Ž.; Vagalinski, Boyan; Lučić, Luka; Mitić, Bojan M.; Mitov, Plamen; Anđelković, Boban D.; Lucić, Sofija Pavković; Vajs, Vlatka; Tomić, Vladimir T.; Raspotnig, Guenther

(Springer, Dordrecht, 2017)

TY  - DATA
AU  -  Makarov, Slobodan E.
AU  - Bodner, Michaela
AU  - Reineke, Doris
AU  - Vujisić, Ljubodrag V.
AU  - Todosijević, Marina
AU  - Antić, Dragan Ž.
AU  - Vagalinski, Boyan
AU  - Lučić, Luka
AU  - Mitić, Bojan M.
AU  - Mitov, Plamen
AU  - Anđelković, Boban D.
AU  - Lucić, Sofija Pavković
AU  - Vajs, Vlatka
AU  - Tomić, Vladimir T.
AU  - Raspotnig, Guenther
PY  - 2017
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3085
PB  - Springer, Dordrecht
T2  - Journal of Chemical Ecology
T1  - Supplementary data for article:  Makarov, S. E.; Bodner, M.; Reineke, D.; Vujisić, L. V.; Todosijević, M. M.; Antić, D. Ž.; Vagalinski, B.; Lučić, L. R.; Mitić, B. M.; Mitov, P.; et al. Chemical Ecology of Cave-Dwelling Millipedes: Defensive Secretions of the Typhloiulini (Diplopoda, Julida, Julidae). Journal of Chemical Ecology 2017, 43 (4), 317–326. 
 https://doi.org/10.1007/s10886-017-0832-1
ER  - 
@misc{
author = " Makarov, Slobodan E. and Bodner, Michaela and Reineke, Doris and Vujisić, Ljubodrag V. and Todosijević, Marina and Antić, Dragan Ž. and Vagalinski, Boyan and Lučić, Luka and Mitić, Bojan M. and Mitov, Plamen and Anđelković, Boban D. and Lucić, Sofija Pavković and Vajs, Vlatka and Tomić, Vladimir T. and Raspotnig, Guenther",
year = "2017",
publisher = "Springer, Dordrecht",
journal = "Journal of Chemical Ecology",
title = "Supplementary data for article:  Makarov, S. E.; Bodner, M.; Reineke, D.; Vujisić, L. V.; Todosijević, M. M.; Antić, D. Ž.; Vagalinski, B.; Lučić, L. R.; Mitić, B. M.; Mitov, P.; et al. Chemical Ecology of Cave-Dwelling Millipedes: Defensive Secretions of the Typhloiulini (Diplopoda, Julida, Julidae). Journal of Chemical Ecology 2017, 43 (4), 317–326. 
 https://doi.org/10.1007/s10886-017-0832-1"
}
Makarov, S. E., Bodner, M., Reineke, D., Vujisić, L. V., Todosijević, M., Antić, D. Ž., Vagalinski, B., Lučić, L., Mitić, B. M., Mitov, P., Anđelković, B. D., Lucić, S. P., Vajs, V., Tomić, V. T.,& Raspotnig, G.. (2017). Supplementary data for article:  Makarov, S. E.; Bodner, M.; Reineke, D.; Vujisić, L. V.; Todosijević, M. M.; Antić, D. Ž.; Vagalinski, B.; Lučić, L. R.; Mitić, B. M.; Mitov, P.; et al. Chemical Ecology of Cave-Dwelling Millipedes: Defensive Secretions of the Typhloiulini (Diplopoda, Julida, Julidae). Journal of Chemical Ecology 2017, 43 (4), 317–326. 
 https://doi.org/10.1007/s10886-017-0832-1. in Journal of Chemical Ecology
Springer, Dordrecht..
Makarov SE, Bodner M, Reineke D, Vujisić LV, Todosijević M, Antić DŽ, Vagalinski B, Lučić L, Mitić BM, Mitov P, Anđelković BD, Lucić SP, Vajs V, Tomić VT, Raspotnig G. Supplementary data for article:  Makarov, S. E.; Bodner, M.; Reineke, D.; Vujisić, L. V.; Todosijević, M. M.; Antić, D. Ž.; Vagalinski, B.; Lučić, L. R.; Mitić, B. M.; Mitov, P.; et al. Chemical Ecology of Cave-Dwelling Millipedes: Defensive Secretions of the Typhloiulini (Diplopoda, Julida, Julidae). Journal of Chemical Ecology 2017, 43 (4), 317–326. 
 https://doi.org/10.1007/s10886-017-0832-1. in Journal of Chemical Ecology. 2017;..
Makarov, Slobodan E., Bodner, Michaela, Reineke, Doris, Vujisić, Ljubodrag V., Todosijević, Marina, Antić, Dragan Ž., Vagalinski, Boyan, Lučić, Luka, Mitić, Bojan M., Mitov, Plamen, Anđelković, Boban D., Lucić, Sofija Pavković, Vajs, Vlatka, Tomić, Vladimir T., Raspotnig, Guenther, "Supplementary data for article:  Makarov, S. E.; Bodner, M.; Reineke, D.; Vujisić, L. V.; Todosijević, M. M.; Antić, D. Ž.; Vagalinski, B.; Lučić, L. R.; Mitić, B. M.; Mitov, P.; et al. Chemical Ecology of Cave-Dwelling Millipedes: Defensive Secretions of the Typhloiulini (Diplopoda, Julida, Julidae). Journal of Chemical Ecology 2017, 43 (4), 317–326. 
 https://doi.org/10.1007/s10886-017-0832-1" in Journal of Chemical Ecology (2017).

Metabolic changes in Euphorbia palusrtis latex after fungal infection

Krstić, Gordana B.; Anđelković, Boban D.; Choi, Young Hae; Vajs, Vlatka; Stević, Tatjana; Tešević, Vele; Gođevac, Dejan

(Pergamon-Elsevier Science Ltd, Oxford, 2016)

TY  - JOUR
AU  - Krstić, Gordana B.
AU  - Anđelković, Boban D.
AU  - Choi, Young Hae
AU  - Vajs, Vlatka
AU  - Stević, Tatjana
AU  - Tešević, Vele
AU  - Gođevac, Dejan
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2335
AB  - The variations of metabolic profile of the latex of wild-growing Euphorbia palustris was carried out using multivariate analysis of NMR spectral data. One population was infected with fungi Fusarium sporotrichioides, Fusarium proliferatum and Alternaria alternata, while the other consisted of healthy plant species. The non-polar metabolites of latex extracts such as benzoyl ingenol-laurate, amyrin decadienoate esters, cis-1,4-polyisoprene, and 24-methylenecycloartanol were identified using H-1 and 2D NMR spectra. Principal component analysis of H-1 NMR data provided a clear discrimination between the latex of infected and healthy plants. Minimum inhibitory concentration and minimum fungicidal concentration values of the latex extracts of healthy and infected plants were determined. The latex of infected plants was found to contain higher levels of benzoyl ingenol-laurate and 24-methylenecycloartanol, of which concentrations were strongly correlated with the antifungal activities of the latex. (C) 2016 Elsevier Ltd. All rights reserved.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Phytochemistry
T1  - Metabolic changes in Euphorbia palusrtis latex after fungal infection
VL  - 131
SP  - 17
EP  - 25
DO  - 10.1016/j.phytochem.2016.08.005
UR  - Kon_3151
ER  - 
@article{
author = "Krstić, Gordana B. and Anđelković, Boban D. and Choi, Young Hae and Vajs, Vlatka and Stević, Tatjana and Tešević, Vele and Gođevac, Dejan",
year = "2016",
abstract = "The variations of metabolic profile of the latex of wild-growing Euphorbia palustris was carried out using multivariate analysis of NMR spectral data. One population was infected with fungi Fusarium sporotrichioides, Fusarium proliferatum and Alternaria alternata, while the other consisted of healthy plant species. The non-polar metabolites of latex extracts such as benzoyl ingenol-laurate, amyrin decadienoate esters, cis-1,4-polyisoprene, and 24-methylenecycloartanol were identified using H-1 and 2D NMR spectra. Principal component analysis of H-1 NMR data provided a clear discrimination between the latex of infected and healthy plants. Minimum inhibitory concentration and minimum fungicidal concentration values of the latex extracts of healthy and infected plants were determined. The latex of infected plants was found to contain higher levels of benzoyl ingenol-laurate and 24-methylenecycloartanol, of which concentrations were strongly correlated with the antifungal activities of the latex. (C) 2016 Elsevier Ltd. All rights reserved.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Phytochemistry",
title = "Metabolic changes in Euphorbia palusrtis latex after fungal infection",
volume = "131",
pages = "17-25",
doi = "10.1016/j.phytochem.2016.08.005",
url = "Kon_3151"
}
Krstić, G. B., Anđelković, B. D., Choi, Y. H., Vajs, V., Stević, T., Tešević, V.,& Gođevac, D.. (2016). Metabolic changes in Euphorbia palusrtis latex after fungal infection. in Phytochemistry
Pergamon-Elsevier Science Ltd, Oxford., 131, 17-25.
https://doi.org/10.1016/j.phytochem.2016.08.005
Kon_3151
Krstić GB, Anđelković BD, Choi YH, Vajs V, Stević T, Tešević V, Gođevac D. Metabolic changes in Euphorbia palusrtis latex after fungal infection. in Phytochemistry. 2016;131:17-25.
doi:10.1016/j.phytochem.2016.08.005
Kon_3151 .
Krstić, Gordana B., Anđelković, Boban D., Choi, Young Hae, Vajs, Vlatka, Stević, Tatjana, Tešević, Vele, Gođevac, Dejan, "Metabolic changes in Euphorbia palusrtis latex after fungal infection" in Phytochemistry, 131 (2016):17-25,
https://doi.org/10.1016/j.phytochem.2016.08.005 .,
Kon_3151 .
10
7
9

The effects of altitude on the chemical composition of Populus type propolis

Gođevac, Dejan; Anđelković, Boban D.; Vajs, Vlatka; Tešević, Vele

(Georg Thieme Verlag Kg, Stuttgart, 2016)

TY  - CONF
AU  - Gođevac, Dejan
AU  - Anđelković, Boban D.
AU  - Vajs, Vlatka
AU  - Tešević, Vele
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2530
PB  - Georg Thieme Verlag Kg, Stuttgart
C3  - Planta Medica
T1  - The effects of altitude on the chemical composition of Populus type propolis
VL  - 82
DO  - 10.1055/s-0036-1596367
UR  - Kon_3346
ER  - 
@conference{
author = "Gođevac, Dejan and Anđelković, Boban D. and Vajs, Vlatka and Tešević, Vele",
year = "2016",
publisher = "Georg Thieme Verlag Kg, Stuttgart",
journal = "Planta Medica",
title = "The effects of altitude on the chemical composition of Populus type propolis",
volume = "82",
doi = "10.1055/s-0036-1596367",
url = "Kon_3346"
}
Gođevac, D., Anđelković, B. D., Vajs, V.,& Tešević, V.. (2016). The effects of altitude on the chemical composition of Populus type propolis. in Planta Medica
Georg Thieme Verlag Kg, Stuttgart., 82.
https://doi.org/10.1055/s-0036-1596367
Kon_3346
Gođevac D, Anđelković BD, Vajs V, Tešević V. The effects of altitude on the chemical composition of Populus type propolis. in Planta Medica. 2016;82.
doi:10.1055/s-0036-1596367
Kon_3346 .
Gođevac, Dejan, Anđelković, Boban D., Vajs, Vlatka, Tešević, Vele, "The effects of altitude on the chemical composition of Populus type propolis" in Planta Medica, 82 (2016),
https://doi.org/10.1055/s-0036-1596367 .,
Kon_3346 .
1
1

Supplementary data for the article: Krstić, G.; Anđelković, B.; Choi, Y. H.; Vajs, V.; Stević, T.; Tešević, V.; Gođevac, D. Metabolic Changes in Euphorbia Palusrtis Latex after Fungal Infection. Phytochemistry 2016, 131, 17–25. https://doi.org/10.1016/j.phytochem.2016.08.005

Krstić, Gordana B.; Anđelković, Boban D.; Choi, Young Hae; Vajs, Vlatka; Stević, Tatjana; Tešević, Vele; Gođevac, Dejan

(Pergamon-Elsevier Science Ltd, Oxford, 2016)

TY  - DATA
AU  - Krstić, Gordana B.
AU  - Anđelković, Boban D.
AU  - Choi, Young Hae
AU  - Vajs, Vlatka
AU  - Stević, Tatjana
AU  - Tešević, Vele
AU  - Gođevac, Dejan
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3564
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Phytochemistry
T1  - Supplementary data for the article: Krstić, G.; Anđelković, B.; Choi, Y. H.; Vajs, V.; Stević, T.; Tešević, V.; Gođevac, D. Metabolic Changes in Euphorbia Palusrtis Latex after Fungal Infection. Phytochemistry 2016, 131, 17–25. https://doi.org/10.1016/j.phytochem.2016.08.005
ER  - 
@misc{
author = "Krstić, Gordana B. and Anđelković, Boban D. and Choi, Young Hae and Vajs, Vlatka and Stević, Tatjana and Tešević, Vele and Gođevac, Dejan",
year = "2016",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Phytochemistry",
title = "Supplementary data for the article: Krstić, G.; Anđelković, B.; Choi, Y. H.; Vajs, V.; Stević, T.; Tešević, V.; Gođevac, D. Metabolic Changes in Euphorbia Palusrtis Latex after Fungal Infection. Phytochemistry 2016, 131, 17–25. https://doi.org/10.1016/j.phytochem.2016.08.005"
}
Krstić, G. B., Anđelković, B. D., Choi, Y. H., Vajs, V., Stević, T., Tešević, V.,& Gođevac, D.. (2016). Supplementary data for the article: Krstić, G.; Anđelković, B.; Choi, Y. H.; Vajs, V.; Stević, T.; Tešević, V.; Gođevac, D. Metabolic Changes in Euphorbia Palusrtis Latex after Fungal Infection. Phytochemistry 2016, 131, 17–25. https://doi.org/10.1016/j.phytochem.2016.08.005. in Phytochemistry
Pergamon-Elsevier Science Ltd, Oxford..
Krstić GB, Anđelković BD, Choi YH, Vajs V, Stević T, Tešević V, Gođevac D. Supplementary data for the article: Krstić, G.; Anđelković, B.; Choi, Y. H.; Vajs, V.; Stević, T.; Tešević, V.; Gođevac, D. Metabolic Changes in Euphorbia Palusrtis Latex after Fungal Infection. Phytochemistry 2016, 131, 17–25. https://doi.org/10.1016/j.phytochem.2016.08.005. in Phytochemistry. 2016;..
Krstić, Gordana B., Anđelković, Boban D., Choi, Young Hae, Vajs, Vlatka, Stević, Tatjana, Tešević, Vele, Gođevac, Dejan, "Supplementary data for the article: Krstić, G.; Anđelković, B.; Choi, Y. H.; Vajs, V.; Stević, T.; Tešević, V.; Gođevac, D. Metabolic Changes in Euphorbia Palusrtis Latex after Fungal Infection. Phytochemistry 2016, 131, 17–25. https://doi.org/10.1016/j.phytochem.2016.08.005" in Phytochemistry (2016).

Supplementary material for the article: Rašković, B.; Vatić, S.; Andelković, B.; Blagojević, V.; Polović, N. Optimizing Storage Conditions to Prevent Cold Denaturation of Trypsin for Sequencing and to Prolong Its Shelf Life. Biochemical Engineering Journal 2016, 105, 168–176. https://doi.org/10.1016/j.bej.2015.09.018

Rašković, Brankica; Vatić, Saša; Anđelković, Boban D.; Blagojević, Vladimir A.; Polović, Natalija

(Elsevier Science Bv, Amsterdam, 2016)

TY  - DATA
AU  - Rašković, Brankica
AU  - Vatić, Saša
AU  - Anđelković, Boban D.
AU  - Blagojević, Vladimir A.
AU  - Polović, Natalija
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3586
PB  - Elsevier Science Bv, Amsterdam
T2  - Biochemical Engineering Journal
T1  - Supplementary material for the article: Rašković, B.; Vatić, S.; Andelković, B.; Blagojević, V.; Polović, N. Optimizing Storage  Conditions to Prevent Cold Denaturation of Trypsin for Sequencing and to Prolong Its Shelf  Life. Biochemical Engineering Journal 2016, 105, 168–176.  https://doi.org/10.1016/j.bej.2015.09.018
ER  - 
@misc{
author = "Rašković, Brankica and Vatić, Saša and Anđelković, Boban D. and Blagojević, Vladimir A. and Polović, Natalija",
year = "2016",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Biochemical Engineering Journal",
title = "Supplementary material for the article: Rašković, B.; Vatić, S.; Andelković, B.; Blagojević, V.; Polović, N. Optimizing Storage  Conditions to Prevent Cold Denaturation of Trypsin for Sequencing and to Prolong Its Shelf  Life. Biochemical Engineering Journal 2016, 105, 168–176.  https://doi.org/10.1016/j.bej.2015.09.018"
}
Rašković, B., Vatić, S., Anđelković, B. D., Blagojević, V. A.,& Polović, N.. (2016). Supplementary material for the article: Rašković, B.; Vatić, S.; Andelković, B.; Blagojević, V.; Polović, N. Optimizing Storage  Conditions to Prevent Cold Denaturation of Trypsin for Sequencing and to Prolong Its Shelf  Life. Biochemical Engineering Journal 2016, 105, 168–176.  https://doi.org/10.1016/j.bej.2015.09.018. in Biochemical Engineering Journal
Elsevier Science Bv, Amsterdam..
Rašković B, Vatić S, Anđelković BD, Blagojević VA, Polović N. Supplementary material for the article: Rašković, B.; Vatić, S.; Andelković, B.; Blagojević, V.; Polović, N. Optimizing Storage  Conditions to Prevent Cold Denaturation of Trypsin for Sequencing and to Prolong Its Shelf  Life. Biochemical Engineering Journal 2016, 105, 168–176.  https://doi.org/10.1016/j.bej.2015.09.018. in Biochemical Engineering Journal. 2016;..
Rašković, Brankica, Vatić, Saša, Anđelković, Boban D., Blagojević, Vladimir A., Polović, Natalija, "Supplementary material for the article: Rašković, B.; Vatić, S.; Andelković, B.; Blagojević, V.; Polović, N. Optimizing Storage  Conditions to Prevent Cold Denaturation of Trypsin for Sequencing and to Prolong Its Shelf  Life. Biochemical Engineering Journal 2016, 105, 168–176.  https://doi.org/10.1016/j.bej.2015.09.018" in Biochemical Engineering Journal (2016).

Optimizing storage conditions to prevent cold denaturation of trypsin for sequencing and to prolong its shelf life

Rašković, Brankica; Vatić, Saša; Anđelković, Boban D.; Blagojević, Vladimir A.; Polović, Natalija

(Elsevier Science Bv, Amsterdam, 2016)

TY  - JOUR
AU  - Rašković, Brankica
AU  - Vatić, Saša
AU  - Anđelković, Boban D.
AU  - Blagojević, Vladimir A.
AU  - Polović, Natalija
PY  - 2016
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2024
AB  - Trypsin is a serine protease with widespread applications, including protein sequencing and typsin mass fingerprinting. In the present study, the storage of trypsin in acidic conditions significantly affected the recovery of activity (40%) after 7 freeze-thaw cycles. Further, trypsin lost parts of its native secondary structure elements, which resulted in a 10% increase in beta-sheet content (band maximum detected at a frequency of 1634 cm in the Fourier transform infrared (FT-IR) spectrum) indicative of freezing-induced denaturation of the protein. The cold storage of trypsin in ammonium bicarbonate (pH 8.2) with the addition of ayoprotectants, such as glycerol or lysine, led to protein stabilization (complete secondary structure content preservation was detected by FT-IR), higher activity recovery ( gt 90%) and modest autolysis ( lt 10%). High activity recovery ( gt 90%) was also detected with the addition of propylene glycol and polyethylene glycol, saccharides and arginine. Nevertheless, trypsin stored at pH 8.2 with the addition of glycerol or lysine was as efficient as untreated trypsin in the trypsin mass fingerprinting analysis of BSA, suggesting that the cold storage of trypsin in slightly alkaline conditions with the addition of cryoprotectants could prolong its shelf life. (C) 2015 Elsevier B.V. All rights reserved.
PB  - Elsevier Science Bv, Amsterdam
T2  - Biochemical Engineering Journal
T1  - Optimizing storage conditions to prevent cold denaturation of trypsin for sequencing and to prolong its shelf life
VL  - 105
SP  - 168
EP  - 176
DO  - 10.1016/j.bej.2015.09.018
UR  - Kon_2979
ER  - 
@article{
author = "Rašković, Brankica and Vatić, Saša and Anđelković, Boban D. and Blagojević, Vladimir A. and Polović, Natalija",
year = "2016",
abstract = "Trypsin is a serine protease with widespread applications, including protein sequencing and typsin mass fingerprinting. In the present study, the storage of trypsin in acidic conditions significantly affected the recovery of activity (40%) after 7 freeze-thaw cycles. Further, trypsin lost parts of its native secondary structure elements, which resulted in a 10% increase in beta-sheet content (band maximum detected at a frequency of 1634 cm in the Fourier transform infrared (FT-IR) spectrum) indicative of freezing-induced denaturation of the protein. The cold storage of trypsin in ammonium bicarbonate (pH 8.2) with the addition of ayoprotectants, such as glycerol or lysine, led to protein stabilization (complete secondary structure content preservation was detected by FT-IR), higher activity recovery ( gt 90%) and modest autolysis ( lt 10%). High activity recovery ( gt 90%) was also detected with the addition of propylene glycol and polyethylene glycol, saccharides and arginine. Nevertheless, trypsin stored at pH 8.2 with the addition of glycerol or lysine was as efficient as untreated trypsin in the trypsin mass fingerprinting analysis of BSA, suggesting that the cold storage of trypsin in slightly alkaline conditions with the addition of cryoprotectants could prolong its shelf life. (C) 2015 Elsevier B.V. All rights reserved.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Biochemical Engineering Journal",
title = "Optimizing storage conditions to prevent cold denaturation of trypsin for sequencing and to prolong its shelf life",
volume = "105",
pages = "168-176",
doi = "10.1016/j.bej.2015.09.018",
url = "Kon_2979"
}
Rašković, B., Vatić, S., Anđelković, B. D., Blagojević, V. A.,& Polović, N.. (2016). Optimizing storage conditions to prevent cold denaturation of trypsin for sequencing and to prolong its shelf life. in Biochemical Engineering Journal
Elsevier Science Bv, Amsterdam., 105, 168-176.
https://doi.org/10.1016/j.bej.2015.09.018
Kon_2979
Rašković B, Vatić S, Anđelković BD, Blagojević VA, Polović N. Optimizing storage conditions to prevent cold denaturation of trypsin for sequencing and to prolong its shelf life. in Biochemical Engineering Journal. 2016;105:168-176.
doi:10.1016/j.bej.2015.09.018
Kon_2979 .
Rašković, Brankica, Vatić, Saša, Anđelković, Boban D., Blagojević, Vladimir A., Polović, Natalija, "Optimizing storage conditions to prevent cold denaturation of trypsin for sequencing and to prolong its shelf life" in Biochemical Engineering Journal, 105 (2016):168-176,
https://doi.org/10.1016/j.bej.2015.09.018 .,
Kon_2979 .
4
5
5