TY  - JOUR
AU  - Cubells-Baeza, N.
AU  - Verhoeckx, K.C.M.
AU  - Larre, C.
AU  - Denery-Papini, Sandra
AU  - Gavrović-Jankulović, Marija
AU  - Diaz Perales, A.
PY  - 2015
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/304
AB  - Measurement of protein transport across the intestinal barrier might be a relevant approach in allergenicity risk assessment. Traditionally, studies on protein transport, were performed using stable cell lines cultured as a monolayer. One of the major advantages of these models is their relatively low price and easy handling. However, monolayers lack a physiologically relevant environment (presence of other cell-types and a mucus layer), which may have an effect on transport characteristics and thus correct prediction of protein allergenicity. This paper summarizes the most widely used epithelial models and discusses their benefits and limitations for measuring protein transport and allergic sensitization to food. © 2016 Elsevier Ltd
T2  - Drug Discovery Today: Disease Models
T1  - Applicability of epithelial models in protein permeability/transport studies and food allergy
SP  - 13
EP  - 21
DO  - 10.1016/j.ddmod.2016.08.002
ER  - 

@article{
author = "Cubells-Baeza, N. and Verhoeckx, K.C.M. and Larre, C. and Denery-Papini, Sandra and Gavrović-Jankulović, Marija and Diaz Perales, A.",
year = "2015",
abstract = "Measurement of protein transport across the intestinal barrier might be a relevant approach in allergenicity risk assessment. Traditionally, studies on protein transport, were performed using stable cell lines cultured as a monolayer. One of the major advantages of these models is their relatively low price and easy handling. However, monolayers lack a physiologically relevant environment (presence of other cell-types and a mucus layer), which may have an effect on transport characteristics and thus correct prediction of protein allergenicity. This paper summarizes the most widely used epithelial models and discusses their benefits and limitations for measuring protein transport and allergic sensitization to food. © 2016 Elsevier Ltd",
journal = "Drug Discovery Today: Disease Models",
title = "Applicability of epithelial models in protein permeability/transport studies and food allergy",
pages = "13-21",
doi = "10.1016/j.ddmod.2016.08.002"
}

Cubells-Baeza, N., Verhoeckx, K.C.M., Larre, C., Denery-Papini, S., Gavrović-Jankulović, M.,& Diaz Perales, A.. (2015). Applicability of epithelial models in protein permeability/transport studies and food allergy. in Drug Discovery Today: Disease Models, 13-21.
https://doi.org/10.1016/j.ddmod.2016.08.002

Cubells-Baeza N, Verhoeckx K, Larre C, Denery-Papini S, Gavrović-Jankulović M, Diaz Perales A. Applicability of epithelial models in protein permeability/transport studies and food allergy. in Drug Discovery Today: Disease Models. 2015;:13-21.
doi:10.1016/j.ddmod.2016.08.002 .

Cubells-Baeza, N., Verhoeckx, K.C.M., Larre, C., Denery-Papini, Sandra, Gavrović-Jankulović, Marija, Diaz Perales, A., "Applicability of epithelial models in protein permeability/transport studies and food allergy" in Drug Discovery Today: Disease Models (2015):13-21,
https://doi.org/10.1016/j.ddmod.2016.08.002 . .