TY  - JOUR
AU  - Stanković, Dalibor
AU  - Mehmeti, Eda
AU  - Katcher, Kurt
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1931
AB  - Nowadays, there is small number of analytical procedures for the quantification of the phenanthrene and its derivatives, quinones and quinonedioximes. In recent years, different studies shows that potential application of these compounds and their complexes possess important role in many search areas, medicine, catalysis, sensors and bioorganic systems. In this paper, for the first time, we offer fast, sensitive, selective and reliable electroanalytical procedure for quantification of phenanthrenequinone dioxime (PQD) based on its oxidation. Also, its electrochemical behavior in water acidic media is given. Possible electrode mechanism based on these measurements was proposed. It was found that by employing differential pulse voltammetry (DPV) in Britton-Robinson buffer solution (BRBS) at pH 3.0 using boron-doped diamond (BDD) electrode calibration curve for PQD quantification was linear in the range of 0.3 to 7.0 mu M with detection limit of 0.22 mu M. Proposed method was successfully applied for the determination of PQD in blood samples with satisfactory recovery (96-102%). Proposed method can be beneficial in the chemistry of dioximes due to advantages of BDD electrode and sensitivity and selectivity of the electroanalytical procedures. (C) 2016 Elsevier B.V. All rights reserved.
PB  - Elsevier Science Sa, Lausanne
T2  - Journal of Electroanalytical Chemistry
T1  - Electrochemical oxidation of phenanthrenequinone dioxime and its quantification using sensing at boron doped diamond electrode
VL  - 770
SP  - 84
EP  - 89
DO  - 10.1016/j.jelechem.2016.03.041
ER  - 

@article{
author = "Stanković, Dalibor and Mehmeti, Eda and Katcher, Kurt",
year = "2016",
abstract = "Nowadays, there is small number of analytical procedures for the quantification of the phenanthrene and its derivatives, quinones and quinonedioximes. In recent years, different studies shows that potential application of these compounds and their complexes possess important role in many search areas, medicine, catalysis, sensors and bioorganic systems. In this paper, for the first time, we offer fast, sensitive, selective and reliable electroanalytical procedure for quantification of phenanthrenequinone dioxime (PQD) based on its oxidation. Also, its electrochemical behavior in water acidic media is given. Possible electrode mechanism based on these measurements was proposed. It was found that by employing differential pulse voltammetry (DPV) in Britton-Robinson buffer solution (BRBS) at pH 3.0 using boron-doped diamond (BDD) electrode calibration curve for PQD quantification was linear in the range of 0.3 to 7.0 mu M with detection limit of 0.22 mu M. Proposed method was successfully applied for the determination of PQD in blood samples with satisfactory recovery (96-102%). Proposed method can be beneficial in the chemistry of dioximes due to advantages of BDD electrode and sensitivity and selectivity of the electroanalytical procedures. (C) 2016 Elsevier B.V. All rights reserved.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Journal of Electroanalytical Chemistry",
title = "Electrochemical oxidation of phenanthrenequinone dioxime and its quantification using sensing at boron doped diamond electrode",
volume = "770",
pages = "84-89",
doi = "10.1016/j.jelechem.2016.03.041"
}

Stanković, D., Mehmeti, E.,& Katcher, K.. (2016). Electrochemical oxidation of phenanthrenequinone dioxime and its quantification using sensing at boron doped diamond electrode. in Journal of Electroanalytical Chemistry
Elsevier Science Sa, Lausanne., 770, 84-89.
https://doi.org/10.1016/j.jelechem.2016.03.041

Stanković D, Mehmeti E, Katcher K. Electrochemical oxidation of phenanthrenequinone dioxime and its quantification using sensing at boron doped diamond electrode. in Journal of Electroanalytical Chemistry. 2016;770:84-89.
doi:10.1016/j.jelechem.2016.03.041 .

Stanković, Dalibor, Mehmeti, Eda, Katcher, Kurt, "Electrochemical oxidation of phenanthrenequinone dioxime and its quantification using sensing at boron doped diamond electrode" in Journal of Electroanalytical Chemistry, 770 (2016):84-89,
https://doi.org/10.1016/j.jelechem.2016.03.041 . .

TY  - JOUR
AU  - Stanković, Dalibor
AU  - Katcher, Kurt
PY  - 2015
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1707
AB  - This paper presents for the first time the study of electrochemical behavior of well known immunosuppressant drug - rapamycin (sirolimus) using boron-doped diamond electrode. Rapamycin provided single and oval-shaped oxidation peak at +1.1 V vs.Ag/AgCl electrode in Britton-Robinson buffer solution at pH 3 confirming highly irreversible behavior of analyte at boron-doped diamond electrode. A differential pulse voltammetry was used for quantification of tested drug under the optimum experimental conditions. The calibration curve was linear over the range from 0.5 to 19.5 mu M (R-2 = 0.9976) with detection limit of 0.22 mu M. Repeatability of ten successfully measurements of three different concentrations (5,10 and 15 mu M) was 2.5, 1.9 and 1.7%, respectively. Influence of most common biomolecules presented in urine samples was evaluated. The suggested analytical methodology was successfully applied for determination of rapamycin in four urine samples with excellent recoveries. The developed approach could be beneficial in analysis of rapamycin in biological samples using boron-doped diamond electrode as up-to-date electrochemical sensor and could represent inexpensive analytical alternative to separation methods.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Electrochimica Acta
T1  - The Immunosuppressive drug - Rapamycin - Electroanalytical Sensing Using Boron-Doped Diamond electrode
VL  - 168
SP  - 76
EP  - 81
DO  - 10.1016/j.electacta.2015.03.200
ER  - 

@article{
author = "Stanković, Dalibor and Katcher, Kurt",
year = "2015",
abstract = "This paper presents for the first time the study of electrochemical behavior of well known immunosuppressant drug - rapamycin (sirolimus) using boron-doped diamond electrode. Rapamycin provided single and oval-shaped oxidation peak at +1.1 V vs.Ag/AgCl electrode in Britton-Robinson buffer solution at pH 3 confirming highly irreversible behavior of analyte at boron-doped diamond electrode. A differential pulse voltammetry was used for quantification of tested drug under the optimum experimental conditions. The calibration curve was linear over the range from 0.5 to 19.5 mu M (R-2 = 0.9976) with detection limit of 0.22 mu M. Repeatability of ten successfully measurements of three different concentrations (5,10 and 15 mu M) was 2.5, 1.9 and 1.7%, respectively. Influence of most common biomolecules presented in urine samples was evaluated. The suggested analytical methodology was successfully applied for determination of rapamycin in four urine samples with excellent recoveries. The developed approach could be beneficial in analysis of rapamycin in biological samples using boron-doped diamond electrode as up-to-date electrochemical sensor and could represent inexpensive analytical alternative to separation methods.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Electrochimica Acta",
title = "The Immunosuppressive drug - Rapamycin - Electroanalytical Sensing Using Boron-Doped Diamond electrode",
volume = "168",
pages = "76-81",
doi = "10.1016/j.electacta.2015.03.200"
}

Stanković, D.,& Katcher, K.. (2015). The Immunosuppressive drug - Rapamycin - Electroanalytical Sensing Using Boron-Doped Diamond electrode. in Electrochimica Acta
Pergamon-Elsevier Science Ltd, Oxford., 168, 76-81.
https://doi.org/10.1016/j.electacta.2015.03.200

Stanković D, Katcher K. The Immunosuppressive drug - Rapamycin - Electroanalytical Sensing Using Boron-Doped Diamond electrode. in Electrochimica Acta. 2015;168:76-81.
doi:10.1016/j.electacta.2015.03.200 .

Stanković, Dalibor, Katcher, Kurt, "The Immunosuppressive drug - Rapamycin - Electroanalytical Sensing Using Boron-Doped Diamond electrode" in Electrochimica Acta, 168 (2015):76-81,
https://doi.org/10.1016/j.electacta.2015.03.200 . .