TY  - JOUR
AU  - Ðurđić, Slađana
AU  - Stanković, V.
AU  - Perić, M.
AU  - Ognjanović, Miloš
AU  - Šovrc, Ľubomír
AU  - Mutić, Jelena
AU  - Stanković, Dalibor
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3716
AB  - In present work boron doped diamond (BDD) electrode was applied for studying electrochemical behavior, as well as for quantitative determination of natural alkaloid, tubocurarine (arrow poison/ TUB). Electrochemical behavior was investigated using several organic solvents and aqueous buffers, at different pHs, as supporting electrolytes. After selection of the most appropriate supporting electrolyte and investigation of its electrochemical behavior, analytical procedures for quantitative analysis of TUB were developed in an acetonitrile/methanol (80:20) mixture and in 1 mol L−1 nitric acid, which had linear quantification ranges from 4 × 10−6 to 1 × 10−4 mol L−1 (LOD = 3.07 × 10−6 mol L−1) and 4 × 10−6 to 9 × 10−5 mol L−1 (LOD = 2.45 × 10−6 mol L−1 and 5.28 × 10−7 mol L−1, depending on the selected peak), respectively. The oxidation mechanism of TUB was proposed from the theoretical aspect. Remarkable selectivity and good sensitivity were obtained after the TUB quantification method was optimized, allowing application of the developed method for TUB quantification in biological fluids, with excellent reproducibility, accuracy and precision.
PB  - Electrochemical Society Inc.
T2  - Journal of the Electrochemical Society
T1  - Electrochemistry of the arrow poison, tubocurarine, using boron doped diamond electrode: Experimental and theoretical approaches
VL  - 166
IS  - 14
SP  - G157
EP  - G161
DO  - 10.1149/2.1241914jes
ER  - 

@article{
author = "Ðurđić, Slađana and Stanković, V. and Perić, M. and Ognjanović, Miloš and Šovrc, Ľubomír and Mutić, Jelena and Stanković, Dalibor",
year = "2019",
abstract = "In present work boron doped diamond (BDD) electrode was applied for studying electrochemical behavior, as well as for quantitative determination of natural alkaloid, tubocurarine (arrow poison/ TUB). Electrochemical behavior was investigated using several organic solvents and aqueous buffers, at different pHs, as supporting electrolytes. After selection of the most appropriate supporting electrolyte and investigation of its electrochemical behavior, analytical procedures for quantitative analysis of TUB were developed in an acetonitrile/methanol (80:20) mixture and in 1 mol L−1 nitric acid, which had linear quantification ranges from 4 × 10−6 to 1 × 10−4 mol L−1 (LOD = 3.07 × 10−6 mol L−1) and 4 × 10−6 to 9 × 10−5 mol L−1 (LOD = 2.45 × 10−6 mol L−1 and 5.28 × 10−7 mol L−1, depending on the selected peak), respectively. The oxidation mechanism of TUB was proposed from the theoretical aspect. Remarkable selectivity and good sensitivity were obtained after the TUB quantification method was optimized, allowing application of the developed method for TUB quantification in biological fluids, with excellent reproducibility, accuracy and precision.",
publisher = "Electrochemical Society Inc.",
journal = "Journal of the Electrochemical Society",
title = "Electrochemistry of the arrow poison, tubocurarine, using boron doped diamond electrode: Experimental and theoretical approaches",
volume = "166",
number = "14",
pages = "G157-G161",
doi = "10.1149/2.1241914jes"
}

Ðurđić, S., Stanković, V., Perić, M., Ognjanović, M., Šovrc, Ľ., Mutić, J.,& Stanković, D.. (2019). Electrochemistry of the arrow poison, tubocurarine, using boron doped diamond electrode: Experimental and theoretical approaches. in Journal of the Electrochemical Society
Electrochemical Society Inc.., 166(14), G157-G161.
https://doi.org/10.1149/2.1241914jes

Ðurđić S, Stanković V, Perić M, Ognjanović M, Šovrc Ľ, Mutić J, Stanković D. Electrochemistry of the arrow poison, tubocurarine, using boron doped diamond electrode: Experimental and theoretical approaches. in Journal of the Electrochemical Society. 2019;166(14):G157-G161.
doi:10.1149/2.1241914jes .

Ðurđić, Slađana, Stanković, V., Perić, M., Ognjanović, Miloš, Šovrc, Ľubomír, Mutić, Jelena, Stanković, Dalibor, "Electrochemistry of the arrow poison, tubocurarine, using boron doped diamond electrode: Experimental and theoretical approaches" in Journal of the Electrochemical Society, 166, no. 14 (2019):G157-G161,
https://doi.org/10.1149/2.1241914jes . .