TY  - THES
AU  - Lekić, Stefan
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5607
AB  - Ovaj rad imao je tri glavna cilja; prvenstveno, prikupljena je relevantna grupa uzoraka kao valjana osnova za naredna ispitivanja: autentični uzorci A. ursinum i simulirani lažni uzorci. Pored toga, A. ursinum je pomešana sa C. majalis i A. maculatum da bi se oponašalo falsifikovanje. Sledeći cilj bio je da se izvrši metabolomički otisak prsta korišćenjem NMR spektroskopije. Ogromni skupovi podataka, dobijeni nakon obrade NMR spektara, obrađeni su putem multivarijantne analize u cilju razlikovanja autentičnih od simuliranih lažnih uzoraka. Poslednji cilj bilo je utvrđivanje strukture biomarkera falsifikovanja iz delimično prečišćenih uzoraka korišćenjem 2D NMR i LC-MS tehnika.
T1  - NMR metabolomička analiza za detekciju adulteranata u biljnoj vrsti allium ursinum
SP  - 2
EP  - 64
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5607
ER  - 

@mastersthesis{
author = "Lekić, Stefan",
year = "2022",
abstract = "Ovaj rad imao je tri glavna cilja; prvenstveno, prikupljena je relevantna grupa uzoraka kao valjana osnova za naredna ispitivanja: autentični uzorci A. ursinum i simulirani lažni uzorci. Pored toga, A. ursinum je pomešana sa C. majalis i A. maculatum da bi se oponašalo falsifikovanje. Sledeći cilj bio je da se izvrši metabolomički otisak prsta korišćenjem NMR spektroskopije. Ogromni skupovi podataka, dobijeni nakon obrade NMR spektara, obrađeni su putem multivarijantne analize u cilju razlikovanja autentičnih od simuliranih lažnih uzoraka. Poslednji cilj bilo je utvrđivanje strukture biomarkera falsifikovanja iz delimično prečišćenih uzoraka korišćenjem 2D NMR i LC-MS tehnika.",
title = "NMR metabolomička analiza za detekciju adulteranata u biljnoj vrsti allium ursinum",
pages = "2-64",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5607"
}

Lekić, S.. (2022). NMR metabolomička analiza za detekciju adulteranata u biljnoj vrsti allium ursinum. , 2-64.
https://hdl.handle.net/21.15107/rcub_cherry_5607

Lekić S. NMR metabolomička analiza za detekciju adulteranata u biljnoj vrsti allium ursinum. 2022;:2-64.
https://hdl.handle.net/21.15107/rcub_cherry_5607 .

Lekić, Stefan, "NMR metabolomička analiza za detekciju adulteranata u biljnoj vrsti allium ursinum" (2022):2-64,
https://hdl.handle.net/21.15107/rcub_cherry_5607 .

TY  - JOUR
AU  - Ivanović, Stefan
AU  - Simić, Katarina
AU  - Lekić, Stefan
AU  - Jadranin, Milka
AU  - Vujisić, Ljubodrag V.
AU  - Gođevac, Dejan
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5655
AB  - Allium ursinum and poisonous adulterants Convallaria majalis and Arum maculatum were used as a model for detection of adulterants in edible plant. A. ursinum samples were spiked with C. majalis and A. maculatum to mimic adulteration. Metabolomic fingerprinting of all samples was performed using 1H NMR spectroscopy, and the resulting data sets were subjected to multivariate data analysis. As a result of this analysis, signals of adulterants were extracted from the data, and the structures of biomarkers of adulteration from partially purified samples were elucidated using 2D NMR and LC-MS techniques. Thus, isovitexin and vicenin II, azetidine-2-carboxylic acid, and trigonelline indicated adulteration of A. ursinum samples with C. majalis. Isovitexin was also recognized to be an indicator of adulteration of A. ursinum with A. maculatum. In conclusion, the case study of A. ursinum suggested that plant metabolomics approach could be utilized for identification of low molecular weight biomarkers of adulteration in edible plants. © 2022 by the authors.
PB  - MDPI
T2  - Metabolites
T1  - Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum
VL  - 12
SP  - 849
DO  - 10.3390/metabo12090849
ER  - 

@article{
author = "Ivanović, Stefan and Simić, Katarina and Lekić, Stefan and Jadranin, Milka and Vujisić, Ljubodrag V. and Gođevac, Dejan",
year = "2022",
abstract = "Allium ursinum and poisonous adulterants Convallaria majalis and Arum maculatum were used as a model for detection of adulterants in edible plant. A. ursinum samples were spiked with C. majalis and A. maculatum to mimic adulteration. Metabolomic fingerprinting of all samples was performed using 1H NMR spectroscopy, and the resulting data sets were subjected to multivariate data analysis. As a result of this analysis, signals of adulterants were extracted from the data, and the structures of biomarkers of adulteration from partially purified samples were elucidated using 2D NMR and LC-MS techniques. Thus, isovitexin and vicenin II, azetidine-2-carboxylic acid, and trigonelline indicated adulteration of A. ursinum samples with C. majalis. Isovitexin was also recognized to be an indicator of adulteration of A. ursinum with A. maculatum. In conclusion, the case study of A. ursinum suggested that plant metabolomics approach could be utilized for identification of low molecular weight biomarkers of adulteration in edible plants. © 2022 by the authors.",
publisher = "MDPI",
journal = "Metabolites",
title = "Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum",
volume = "12",
pages = "849",
doi = "10.3390/metabo12090849"
}

Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L. V.,& Gođevac, D.. (2022). Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites
MDPI., 12, 849.
https://doi.org/10.3390/metabo12090849

Ivanović S, Simić K, Lekić S, Jadranin M, Vujisić LV, Gođevac D. Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites. 2022;12:849.
doi:10.3390/metabo12090849 .

Ivanović, Stefan, Simić, Katarina, Lekić, Stefan, Jadranin, Milka, Vujisić, Ljubodrag V., Gođevac, Dejan, "Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum" in Metabolites, 12 (2022):849,
https://doi.org/10.3390/metabo12090849 . .

TY  - DATA
AU  - Ivanović, Stefan
AU  - Simić, Katarina
AU  - Lekić, Stefan
AU  - Jadranin, Milka
AU  - Vujisić, Ljubodrag V.
AU  - Gođevac, Dejan
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5660
AB  - Allium ursinum and poisonous adulterants Convallaria majalis and Arum maculatum were used as a model for detection of adulterants in edible plant. A. ursinum samples were spiked with C. majalis and A. maculatum to mimic adulteration. Metabolomic fingerprinting of all samples was performed using 1H NMR spectroscopy, and the resulting data sets were subjected to multivariate data analysis. As a result of this analysis, signals of adulterants were extracted from the data, and the structures of biomarkers of adulteration from partially purified samples were elucidated using 2D NMR and LC-MS techniques. Thus, isovitexin and vicenin II, azetidine-2-carboxylic acid, and trigonelline indicated adulteration of A. ursinum samples with C. majalis. Isovitexin was also recognized to be an indicator of adulteration of A. ursinum with A. maculatum. In conclusion, the case study of A. ursinum suggested that plant metabolomics approach could be utilized for identification of low molecular weight biomarkers of adulteration in edible plants. © 2022 by the authors.
PB  - MDPI
T2  - Metabolites
T1  - Supplementary material for: Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L.,& Gođevac, D.. (2022). Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites MDPI., 12, 849. https://doi.org/10.3390/metabo12090849
VL  - 12
SP  - 849
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5660
ER  - 

@misc{
author = "Ivanović, Stefan and Simić, Katarina and Lekić, Stefan and Jadranin, Milka and Vujisić, Ljubodrag V. and Gođevac, Dejan",
year = "2022",
abstract = "Allium ursinum and poisonous adulterants Convallaria majalis and Arum maculatum were used as a model for detection of adulterants in edible plant. A. ursinum samples were spiked with C. majalis and A. maculatum to mimic adulteration. Metabolomic fingerprinting of all samples was performed using 1H NMR spectroscopy, and the resulting data sets were subjected to multivariate data analysis. As a result of this analysis, signals of adulterants were extracted from the data, and the structures of biomarkers of adulteration from partially purified samples were elucidated using 2D NMR and LC-MS techniques. Thus, isovitexin and vicenin II, azetidine-2-carboxylic acid, and trigonelline indicated adulteration of A. ursinum samples with C. majalis. Isovitexin was also recognized to be an indicator of adulteration of A. ursinum with A. maculatum. In conclusion, the case study of A. ursinum suggested that plant metabolomics approach could be utilized for identification of low molecular weight biomarkers of adulteration in edible plants. © 2022 by the authors.",
publisher = "MDPI",
journal = "Metabolites",
title = "Supplementary material for: Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L.,& Gođevac, D.. (2022). Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites MDPI., 12, 849. https://doi.org/10.3390/metabo12090849",
volume = "12",
pages = "849",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5660"
}

Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L. V.,& Gođevac, D.. (2022). Supplementary material for: Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L.,& Gođevac, D.. (2022). Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites MDPI., 12, 849. https://doi.org/10.3390/metabo12090849. in Metabolites
MDPI., 12, 849.
https://hdl.handle.net/21.15107/rcub_cherry_5660

Ivanović S, Simić K, Lekić S, Jadranin M, Vujisić LV, Gođevac D. Supplementary material for: Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L.,& Gođevac, D.. (2022). Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites MDPI., 12, 849. https://doi.org/10.3390/metabo12090849. in Metabolites. 2022;12:849.
https://hdl.handle.net/21.15107/rcub_cherry_5660 .

Ivanović, Stefan, Simić, Katarina, Lekić, Stefan, Jadranin, Milka, Vujisić, Ljubodrag V., Gođevac, Dejan, "Supplementary material for: Ivanović, S., Simić, K., Lekić, S., Jadranin, M., Vujisić, L.,& Gođevac, D.. (2022). Plant Metabolomics as a Tool for Detecting Adulterants in Edible Plant: A Case Study of Allium ursinum. in Metabolites MDPI., 12, 849. https://doi.org/10.3390/metabo12090849" in Metabolites, 12 (2022):849,
https://hdl.handle.net/21.15107/rcub_cherry_5660 .

TY  - THES
AU  - Lekić, Stefan
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4732
AB  - Biljna vrsta Euphorbia palustris pripada rodu Euphorbia iz familije Euphorbiaceae. U
oviru ovog završnog rada iz biljne vrste E. palustris izolovan je, a potom i okarakterisan
triterpen cikloartanskog tipa. Izolovanje i ispitivanje biloške aktivnosti
triterpena iz lateksa navedene biljne vrste može doprineti primeni ovih jedinjena u
medicinske svrhe. Pokazalo se da mnogi diterpeni i triterpeni izolovani iz lateksa
biljnih vrsta Euphorbia pokazaju značajne biloške aktivnosti, kao što su antivirusne,
anti-HIV, antibakterijske, antitumorne itd.
T1  - Izolovanje i karakterizacija triterpena
cikloartanskog tipa iz biljke Euphorbia palustris
SP  - 1
EP  - 20
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4732
ER  - 

@misc{
author = "Lekić, Stefan",
year = "2021",
abstract = "Biljna vrsta Euphorbia palustris pripada rodu Euphorbia iz familije Euphorbiaceae. U
oviru ovog završnog rada iz biljne vrste E. palustris izolovan je, a potom i okarakterisan
triterpen cikloartanskog tipa. Izolovanje i ispitivanje biloške aktivnosti
triterpena iz lateksa navedene biljne vrste može doprineti primeni ovih jedinjena u
medicinske svrhe. Pokazalo se da mnogi diterpeni i triterpeni izolovani iz lateksa
biljnih vrsta Euphorbia pokazaju značajne biloške aktivnosti, kao što su antivirusne,
anti-HIV, antibakterijske, antitumorne itd.",
title = "Izolovanje i karakterizacija triterpena
cikloartanskog tipa iz biljke Euphorbia palustris",
pages = "1-20",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4732"
}

Lekić, S.. (2021). Izolovanje i karakterizacija triterpena
cikloartanskog tipa iz biljke Euphorbia palustris. , 1-20.
https://hdl.handle.net/21.15107/rcub_cherry_4732

Lekić S. Izolovanje i karakterizacija triterpena
cikloartanskog tipa iz biljke Euphorbia palustris. 2021;:1-20.
https://hdl.handle.net/21.15107/rcub_cherry_4732 .

Lekić, Stefan, "Izolovanje i karakterizacija triterpena
cikloartanskog tipa iz biljke Euphorbia palustris" (2021):1-20,
https://hdl.handle.net/21.15107/rcub_cherry_4732 .