TY  - JOUR
AU  - Cinková, Kristína
AU  - Kianicková, Kristína
AU  - Stanković, Dalibor
AU  - Vojs, Marian
AU  - Marton, Marian
AU  - Šovrc, Ľubomír
PY  - 2018
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2102
AB  - In this work, the electrochemical oxidation and subsequent determination of uric acid was investigated using boron-doped diamond electrodes with various B/C ratios (0-2000 ppm). The cyclic voltammetric study showed one irreversible oxidation peak at +(1.1-1.25) V (vs. Ag/AgCl/3 M KCl) in the presence of Britton-Robinson buffer (pH 2.25) depending on the boron content. Employing differential pulse voltammetry using the 2000 ppm boron-doped diamond electrode the acquired analytical parameters were as follows: a limit of detection of 7.7 M, a limit of quantification of 26 M and intra-day repeatability (relative standard deviation of 2.9% for n = 15). After performing an interference study, the method was applied to the determination of uric acid in biological samples (human urine). The uric acid concentrations determined in the urine samples were compared with the reference values stated in the literature. The proposed methodology using boron-doped diamond electrodes could find applications in uric acid sensing within clinical, pharmaceutical and environmental analysis.
PB  - Royal Soc Chemistry, Cambridge
T2  - Analytical Methods
T1  - The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid
VL  - 10
IS  - 9
SP  - 991
EP  - 996
DO  - 10.1039/c7ay02720f
ER  - 

@article{
author = "Cinková, Kristína and Kianicková, Kristína and Stanković, Dalibor and Vojs, Marian and Marton, Marian and Šovrc, Ľubomír",
year = "2018",
abstract = "In this work, the electrochemical oxidation and subsequent determination of uric acid was investigated using boron-doped diamond electrodes with various B/C ratios (0-2000 ppm). The cyclic voltammetric study showed one irreversible oxidation peak at +(1.1-1.25) V (vs. Ag/AgCl/3 M KCl) in the presence of Britton-Robinson buffer (pH 2.25) depending on the boron content. Employing differential pulse voltammetry using the 2000 ppm boron-doped diamond electrode the acquired analytical parameters were as follows: a limit of detection of 7.7 M, a limit of quantification of 26 M and intra-day repeatability (relative standard deviation of 2.9% for n = 15). After performing an interference study, the method was applied to the determination of uric acid in biological samples (human urine). The uric acid concentrations determined in the urine samples were compared with the reference values stated in the literature. The proposed methodology using boron-doped diamond electrodes could find applications in uric acid sensing within clinical, pharmaceutical and environmental analysis.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Analytical Methods",
title = "The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid",
volume = "10",
number = "9",
pages = "991-996",
doi = "10.1039/c7ay02720f"
}

Cinková, K., Kianicková, K., Stanković, D., Vojs, M., Marton, M.,& Šovrc, Ľ.. (2018). The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid. in Analytical Methods
Royal Soc Chemistry, Cambridge., 10(9), 991-996.
https://doi.org/10.1039/c7ay02720f

Cinková K, Kianicková K, Stanković D, Vojs M, Marton M, Šovrc Ľ. The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid. in Analytical Methods. 2018;10(9):991-996.
doi:10.1039/c7ay02720f .

Cinková, Kristína, Kianicková, Kristína, Stanković, Dalibor, Vojs, Marian, Marton, Marian, Šovrc, Ľubomír, "The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid" in Analytical Methods, 10, no. 9 (2018):991-996,
https://doi.org/10.1039/c7ay02720f . .

TY  - JOUR
AU  - Samiec, Petr
AU  - Šovrc, Ľubomír
AU  - Stanković, Dalibor
AU  - Vojs, Marian
AU  - Marton, Marian
AU  - Navrátilová, Zuzana
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2442
AB  - The boron-doped diamond electrodes (BDDEs) with different dopant levels were applied as advanced, mercury-free and modification-free electroanalytical platforms for simple and reliable quantification of benzodiazepines, bromazepam (BZ) and alprazolam (ALZ). Cyclic voltammetric measurements revealed that the electrode reactions of both analytes were manifested by one irreversible and diffusion-controlled reduction peak at -1.10V in Britton-Robinson buffer of pH 11 for BZ using lab-made BDDE with 1000 ppm B/C ratio and -0.84V in BR buffer of pH 5 for ALZ using commercial BDDE with 1000 ppm B/C ratio. Differential pulse voltammetry was used for construction of calibration curves for BZ and ALZ, respectively, with the analytical parameters as follows: the linear dynamic ranges of 1 x 10(-6)-1 x 10(-4) and 8 x 10(-7)-1 x 10(-4) mol/L, the detection limit of 3.1 x 10(-7) and 6.4 x 10(-7) mol/L and the excellent repeatability with the relative standard deviation below 3% for both drugs. The developed methods were applied to analysis of the pharmaceutical tablets with the recoveries from 97.33 to 100.85% for BZ and from 94.14 to 101.32% for ALZ. The usage of BDDEs as advanced electrochemical sensors in drug analysis represents a facile and effective analytical approach which may replace mercury-based sensors and chemically modified electrodes in previous benzodiazepines sensing.
PB  - Elsevier Science Sa, Lausanne
T2  - Sensors and Actuators B: Chemical
T1  - Mercury-free and modification-free electroanalytical approach towards bromazepam and alprazolam sensing: A facile and efficient assay for their quantification in pharmaceuticals using boron-doped diamond electrodes
VL  - 245
SP  - 963
EP  - 971
DO  - 10.1016/j.snb.2017.02.023
ER  - 

@article{
author = "Samiec, Petr and Šovrc, Ľubomír and Stanković, Dalibor and Vojs, Marian and Marton, Marian and Navrátilová, Zuzana",
year = "2017",
abstract = "The boron-doped diamond electrodes (BDDEs) with different dopant levels were applied as advanced, mercury-free and modification-free electroanalytical platforms for simple and reliable quantification of benzodiazepines, bromazepam (BZ) and alprazolam (ALZ). Cyclic voltammetric measurements revealed that the electrode reactions of both analytes were manifested by one irreversible and diffusion-controlled reduction peak at -1.10V in Britton-Robinson buffer of pH 11 for BZ using lab-made BDDE with 1000 ppm B/C ratio and -0.84V in BR buffer of pH 5 for ALZ using commercial BDDE with 1000 ppm B/C ratio. Differential pulse voltammetry was used for construction of calibration curves for BZ and ALZ, respectively, with the analytical parameters as follows: the linear dynamic ranges of 1 x 10(-6)-1 x 10(-4) and 8 x 10(-7)-1 x 10(-4) mol/L, the detection limit of 3.1 x 10(-7) and 6.4 x 10(-7) mol/L and the excellent repeatability with the relative standard deviation below 3% for both drugs. The developed methods were applied to analysis of the pharmaceutical tablets with the recoveries from 97.33 to 100.85% for BZ and from 94.14 to 101.32% for ALZ. The usage of BDDEs as advanced electrochemical sensors in drug analysis represents a facile and effective analytical approach which may replace mercury-based sensors and chemically modified electrodes in previous benzodiazepines sensing.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Sensors and Actuators B: Chemical",
title = "Mercury-free and modification-free electroanalytical approach towards bromazepam and alprazolam sensing: A facile and efficient assay for their quantification in pharmaceuticals using boron-doped diamond electrodes",
volume = "245",
pages = "963-971",
doi = "10.1016/j.snb.2017.02.023"
}

Samiec, P., Šovrc, Ľ., Stanković, D., Vojs, M., Marton, M.,& Navrátilová, Z.. (2017). Mercury-free and modification-free electroanalytical approach towards bromazepam and alprazolam sensing: A facile and efficient assay for their quantification in pharmaceuticals using boron-doped diamond electrodes. in Sensors and Actuators B: Chemical
Elsevier Science Sa, Lausanne., 245, 963-971.
https://doi.org/10.1016/j.snb.2017.02.023

Samiec P, Šovrc Ľ, Stanković D, Vojs M, Marton M, Navrátilová Z. Mercury-free and modification-free electroanalytical approach towards bromazepam and alprazolam sensing: A facile and efficient assay for their quantification in pharmaceuticals using boron-doped diamond electrodes. in Sensors and Actuators B: Chemical. 2017;245:963-971.
doi:10.1016/j.snb.2017.02.023 .

Samiec, Petr, Šovrc, Ľubomír, Stanković, Dalibor, Vojs, Marian, Marton, Marian, Navrátilová, Zuzana, "Mercury-free and modification-free electroanalytical approach towards bromazepam and alprazolam sensing: A facile and efficient assay for their quantification in pharmaceuticals using boron-doped diamond electrodes" in Sensors and Actuators B: Chemical, 245 (2017):963-971,
https://doi.org/10.1016/j.snb.2017.02.023 . .