Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200168 (University of Belgrade, Faculty of Chemistry)

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Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200168 (University of Belgrade, Faculty of Chemistry) (en)
Ministarstvo prosvete, nauke i tehnološkog razvoja Republike Srbije, Ugovor br. 451-03-68/2020-14/200168 (Univerzitet u Beogradu, Hemijski fakultet) (sr_RS)
Министарство просвете, науке и технолошког развоја Републике Србије, Уговор бр. 451-03-68/2020-14/200168 (Универзитет у Београду, Хемијски факултет) (sr)
Authors

Publications

Novel derivatives of aroylacrylic acid phenylamides as inducers of apoptosis through the ROS-mediated pathway in several cancer cell lines

Vujatović, Tamara B.; Vitorović-Todorović, Maja D.; Cvijetić, Ilija; Vasović, Tamara; Nikolić, Milan; Novaković, Irena T.; Bjelogrlić, Snežana K.

(Elsevier, 2022)

TY  - JOUR
AU  - Vujatović, Tamara B.
AU  - Vitorović-Todorović, Maja D.
AU  - Cvijetić, Ilija
AU  - Vasović, Tamara
AU  - Nikolić, Milan
AU  - Novaković, Irena T.
AU  - Bjelogrlić, Snežana K.
PY  - 2022
UR  - https://www.sciencedirect.com/science/article/pii/S0022286021018287
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4761
AB  - In the present work, the α,β-double bond of the aroylacrylic acid phenylamides was suitably modified to optimize the toxicity–antiproliferative activity ratio of the resulting compounds 1–5. The phenylamides were modified by Michael's addition of suitably chosen piperidine-containing fragments: 1-amino-N-benzylpiperidine (a1), 4-benzylpiperidine (a2), and N,N-dimethyl-N-[2-(1-piperazinyl)-ethyl]amine (a3). The compounds exerted micromolar activity toward three cancer cell lines, A549, LoVo, and Skov-3, causing apoptotic cell death. It was shown that the nature of the cyclic amine moiety at position C2 of the compounds is probably the primary determinant of anticancer activity toward tested cell lines and the acute toxicity toward brine shrimp (Artemia salina). The majority of compounds revealed the ability to vigorously induce mitochondrial superoxide anion generation in all treated cell lines, which together with cell cycle arrest at the S phase and activation of intrinsic caspase cascade, indicates the possibility that apoptosis was triggered due to irreparable chromosomal damage by acute oxidative stress. Two derivatives also exerted significant antibacterial activity with one order of magnitude higher potency than chloramphenicol in most of the investigated bacterial strains. Also, the drug-like properties for all compounds were estimated by available software tools.
PB  - Elsevier
T2  - Journal of Molecular Structure
T1  - Novel derivatives of aroylacrylic acid phenylamides as inducers of apoptosis through the ROS-mediated pathway in several cancer cell lines
VL  - 1250
SP  - 131702
DO  - 10.1016/j.molstruc.2021.131702
ER  - 
@article{
author = "Vujatović, Tamara B. and Vitorović-Todorović, Maja D. and Cvijetić, Ilija and Vasović, Tamara and Nikolić, Milan and Novaković, Irena T. and Bjelogrlić, Snežana K.",
year = "2022",
abstract = "In the present work, the α,β-double bond of the aroylacrylic acid phenylamides was suitably modified to optimize the toxicity–antiproliferative activity ratio of the resulting compounds 1–5. The phenylamides were modified by Michael's addition of suitably chosen piperidine-containing fragments: 1-amino-N-benzylpiperidine (a1), 4-benzylpiperidine (a2), and N,N-dimethyl-N-[2-(1-piperazinyl)-ethyl]amine (a3). The compounds exerted micromolar activity toward three cancer cell lines, A549, LoVo, and Skov-3, causing apoptotic cell death. It was shown that the nature of the cyclic amine moiety at position C2 of the compounds is probably the primary determinant of anticancer activity toward tested cell lines and the acute toxicity toward brine shrimp (Artemia salina). The majority of compounds revealed the ability to vigorously induce mitochondrial superoxide anion generation in all treated cell lines, which together with cell cycle arrest at the S phase and activation of intrinsic caspase cascade, indicates the possibility that apoptosis was triggered due to irreparable chromosomal damage by acute oxidative stress. Two derivatives also exerted significant antibacterial activity with one order of magnitude higher potency than chloramphenicol in most of the investigated bacterial strains. Also, the drug-like properties for all compounds were estimated by available software tools.",
publisher = "Elsevier",
journal = "Journal of Molecular Structure",
title = "Novel derivatives of aroylacrylic acid phenylamides as inducers of apoptosis through the ROS-mediated pathway in several cancer cell lines",
volume = "1250",
pages = "131702",
doi = "10.1016/j.molstruc.2021.131702"
}
Vujatović, T. B., Vitorović-Todorović, M. D., Cvijetić, I., Vasović, T., Nikolić, M., Novaković, I. T.,& Bjelogrlić, S. K.. (2022). Novel derivatives of aroylacrylic acid phenylamides as inducers of apoptosis through the ROS-mediated pathway in several cancer cell lines. in Journal of Molecular Structure
Elsevier., 1250, 131702.
https://doi.org/10.1016/j.molstruc.2021.131702
Vujatović TB, Vitorović-Todorović MD, Cvijetić I, Vasović T, Nikolić M, Novaković IT, Bjelogrlić SK. Novel derivatives of aroylacrylic acid phenylamides as inducers of apoptosis through the ROS-mediated pathway in several cancer cell lines. in Journal of Molecular Structure. 2022;1250:131702.
doi:10.1016/j.molstruc.2021.131702 .
Vujatović, Tamara B., Vitorović-Todorović, Maja D., Cvijetić, Ilija, Vasović, Tamara, Nikolić, Milan, Novaković, Irena T., Bjelogrlić, Snežana K., "Novel derivatives of aroylacrylic acid phenylamides as inducers of apoptosis through the ROS-mediated pathway in several cancer cell lines" in Journal of Molecular Structure, 1250 (2022):131702,
https://doi.org/10.1016/j.molstruc.2021.131702 . .

Human health risks and benefits assessment based on OCPs, PCBs, toxic elements and fatty acids in the pelagic fish species from the Adriatic Sea

Milićević, Tijana; Herceg Romanić, Snježana; Popović, Aleksandar R.; Mustać, Bosiljka; Đinović-Stojanović, Jasna; Jovanović, Gordana; Relić, Dubravka

(Elsevier, 2022)

TY  - JOUR
AU  - Milićević, Tijana
AU  - Herceg Romanić, Snježana
AU  - Popović, Aleksandar R.
AU  - Mustać, Bosiljka
AU  - Đinović-Stojanović, Jasna
AU  - Jovanović, Gordana
AU  - Relić, Dubravka
PY  - 2022
UR  - https://www.sciencedirect.com/science/article/pii/S0045653521025406
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4664
AB  - Benefits and risks of the fish consumption should be assessed to balance the ingestion of healthy omega-3 fatty acids and adverse chemicals. Persistent organic pollutants-POPs (organochlorine pesticides-OCPs and polychlorinated biphenyls-PCB), macro- and micro-elements and fatty acid contents were determined in six fish species from the Adriatic Sea to assess health risks for consumers (worst-case scenario, diseases development risks and benefit-risk). 16 element, 24 POPs and 14 fatty acid contents were determined in six pelagic species which can be used in human diet. Element concentrations were determined by inductively coupled plasma mass spectrometry (ICP-MS), POPs by high-resolution gas chromatography and fatty acid content by gas–liquid chromatography. Diet based on chub mackerel and round sardinella showed lower daily intake (DI) of POPs and highest DI of essential omega-3 fatty acids than other investigated species. Lower ingestion of toxic elements can be observed by consuming anchovy and round sardinella. Based on POP concentrations, there was not observed non-carcinogenic (HI) nor carcinogenic (CR) risks for consumers. Based on element concentrations, there was low HI (0.1 ≥ HI ≥ 1), while the maximum HIs and outlier values (horse mackerel and anchovy samples) implied the presence of HI (HI > 1). The most significant contributor to total non-carcinogenic and carcinogenic risks was inorganic arsenic (inorganic As). Acceptable CR for consumers was assessed, but maximum CR for consumers of horse mackerel and anchovy (CR ≥ 1 × 10–6) showed adverse effects on human health. There were low HIs for developing cardiovascular, nervous, and reproductive diseases, and maximum HIs were higher than 1. Acceptable (1 × 10−4≥CR ≥ 1 × 10−6) risks were observed for developing cancer of nervous system and reproductive organs. Among investigated fish samples, those with higher ƩBR (benefit-risks) and BR for arsenic (As) than median value have a higher risk than benefits in the human diet.
PB  - Elsevier
T2  - Chemosphere
T1  - Human health risks and benefits assessment based on OCPs, PCBs, toxic elements and fatty acids in the pelagic fish species from the Adriatic Sea
VL  - 287
SP  - 132068
DO  - 10.1016/j.chemosphere.2021.132068
ER  - 
@article{
author = "Milićević, Tijana and Herceg Romanić, Snježana and Popović, Aleksandar R. and Mustać, Bosiljka and Đinović-Stojanović, Jasna and Jovanović, Gordana and Relić, Dubravka",
year = "2022",
abstract = "Benefits and risks of the fish consumption should be assessed to balance the ingestion of healthy omega-3 fatty acids and adverse chemicals. Persistent organic pollutants-POPs (organochlorine pesticides-OCPs and polychlorinated biphenyls-PCB), macro- and micro-elements and fatty acid contents were determined in six fish species from the Adriatic Sea to assess health risks for consumers (worst-case scenario, diseases development risks and benefit-risk). 16 element, 24 POPs and 14 fatty acid contents were determined in six pelagic species which can be used in human diet. Element concentrations were determined by inductively coupled plasma mass spectrometry (ICP-MS), POPs by high-resolution gas chromatography and fatty acid content by gas–liquid chromatography. Diet based on chub mackerel and round sardinella showed lower daily intake (DI) of POPs and highest DI of essential omega-3 fatty acids than other investigated species. Lower ingestion of toxic elements can be observed by consuming anchovy and round sardinella. Based on POP concentrations, there was not observed non-carcinogenic (HI) nor carcinogenic (CR) risks for consumers. Based on element concentrations, there was low HI (0.1 ≥ HI ≥ 1), while the maximum HIs and outlier values (horse mackerel and anchovy samples) implied the presence of HI (HI > 1). The most significant contributor to total non-carcinogenic and carcinogenic risks was inorganic arsenic (inorganic As). Acceptable CR for consumers was assessed, but maximum CR for consumers of horse mackerel and anchovy (CR ≥ 1 × 10–6) showed adverse effects on human health. There were low HIs for developing cardiovascular, nervous, and reproductive diseases, and maximum HIs were higher than 1. Acceptable (1 × 10−4≥CR ≥ 1 × 10−6) risks were observed for developing cancer of nervous system and reproductive organs. Among investigated fish samples, those with higher ƩBR (benefit-risks) and BR for arsenic (As) than median value have a higher risk than benefits in the human diet.",
publisher = "Elsevier",
journal = "Chemosphere",
title = "Human health risks and benefits assessment based on OCPs, PCBs, toxic elements and fatty acids in the pelagic fish species from the Adriatic Sea",
volume = "287",
pages = "132068",
doi = "10.1016/j.chemosphere.2021.132068"
}
Milićević, T., Herceg Romanić, S., Popović, A. R., Mustać, B., Đinović-Stojanović, J., Jovanović, G.,& Relić, D.. (2022). Human health risks and benefits assessment based on OCPs, PCBs, toxic elements and fatty acids in the pelagic fish species from the Adriatic Sea. in Chemosphere
Elsevier., 287, 132068.
https://doi.org/10.1016/j.chemosphere.2021.132068
Milićević T, Herceg Romanić S, Popović AR, Mustać B, Đinović-Stojanović J, Jovanović G, Relić D. Human health risks and benefits assessment based on OCPs, PCBs, toxic elements and fatty acids in the pelagic fish species from the Adriatic Sea. in Chemosphere. 2022;287:132068.
doi:10.1016/j.chemosphere.2021.132068 .
Milićević, Tijana, Herceg Romanić, Snježana, Popović, Aleksandar R., Mustać, Bosiljka, Đinović-Stojanović, Jasna, Jovanović, Gordana, Relić, Dubravka, "Human health risks and benefits assessment based on OCPs, PCBs, toxic elements and fatty acids in the pelagic fish species from the Adriatic Sea" in Chemosphere, 287 (2022):132068,
https://doi.org/10.1016/j.chemosphere.2021.132068 . .
1

Supplementary data for the article: Milićević, T.; Romanić, S. H.; Popović, A.; Mustać, B.; Đinović-Stojanović, J.; Jovanović, G.; Relić, D. Human Health Risks and Benefits Assessment Based on OCPs, PCBs, Toxic Elements and Fatty Acids in the Pelagic Fish Species from the Adriatic Sea. Chemosphere 2022, 287, 132068. https://doi.org/10.1016/j.chemosphere.2021.132068.

Milićević, Tijana; Herceg Romanić, Snježana; Popović, Aleksandar R.; Mustać, Bosiljka; Đinović-Stojanović, Jasna; Jovanović, Gordana; Relić, Dubravka

(Elsevier, 2022)

TY  - DATA
AU  - Milićević, Tijana
AU  - Herceg Romanić, Snježana
AU  - Popović, Aleksandar R.
AU  - Mustać, Bosiljka
AU  - Đinović-Stojanović, Jasna
AU  - Jovanović, Gordana
AU  - Relić, Dubravka
PY  - 2022
UR  - https://www.sciencedirect.com/science/article/pii/S0045653521025406
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4665
PB  - Elsevier
T2  - Chemosphere
T1  - Supplementary data for the article: Milićević, T.; Romanić, S. H.; Popović, A.; Mustać, B.; Đinović-Stojanović, J.; Jovanović, G.; Relić, D. Human Health Risks and Benefits Assessment Based on OCPs, PCBs, Toxic Elements and Fatty Acids in the Pelagic Fish Species from the Adriatic Sea. Chemosphere 2022, 287, 132068. https://doi.org/10.1016/j.chemosphere.2021.132068.
ER  - 
@misc{
author = "Milićević, Tijana and Herceg Romanić, Snježana and Popović, Aleksandar R. and Mustać, Bosiljka and Đinović-Stojanović, Jasna and Jovanović, Gordana and Relić, Dubravka",
year = "2022",
publisher = "Elsevier",
journal = "Chemosphere",
title = "Supplementary data for the article: Milićević, T.; Romanić, S. H.; Popović, A.; Mustać, B.; Đinović-Stojanović, J.; Jovanović, G.; Relić, D. Human Health Risks and Benefits Assessment Based on OCPs, PCBs, Toxic Elements and Fatty Acids in the Pelagic Fish Species from the Adriatic Sea. Chemosphere 2022, 287, 132068. https://doi.org/10.1016/j.chemosphere.2021.132068."
}
Milićević, T., Herceg Romanić, S., Popović, A. R., Mustać, B., Đinović-Stojanović, J., Jovanović, G.,& Relić, D.. (2022). Supplementary data for the article: Milićević, T.; Romanić, S. H.; Popović, A.; Mustać, B.; Đinović-Stojanović, J.; Jovanović, G.; Relić, D. Human Health Risks and Benefits Assessment Based on OCPs, PCBs, Toxic Elements and Fatty Acids in the Pelagic Fish Species from the Adriatic Sea. Chemosphere 2022, 287, 132068. https://doi.org/10.1016/j.chemosphere.2021.132068.. in Chemosphere
Elsevier..
Milićević T, Herceg Romanić S, Popović AR, Mustać B, Đinović-Stojanović J, Jovanović G, Relić D. Supplementary data for the article: Milićević, T.; Romanić, S. H.; Popović, A.; Mustać, B.; Đinović-Stojanović, J.; Jovanović, G.; Relić, D. Human Health Risks and Benefits Assessment Based on OCPs, PCBs, Toxic Elements and Fatty Acids in the Pelagic Fish Species from the Adriatic Sea. Chemosphere 2022, 287, 132068. https://doi.org/10.1016/j.chemosphere.2021.132068.. in Chemosphere. 2022;..
Milićević, Tijana, Herceg Romanić, Snježana, Popović, Aleksandar R., Mustać, Bosiljka, Đinović-Stojanović, Jasna, Jovanović, Gordana, Relić, Dubravka, "Supplementary data for the article: Milićević, T.; Romanić, S. H.; Popović, A.; Mustać, B.; Đinović-Stojanović, J.; Jovanović, G.; Relić, D. Human Health Risks and Benefits Assessment Based on OCPs, PCBs, Toxic Elements and Fatty Acids in the Pelagic Fish Species from the Adriatic Sea. Chemosphere 2022, 287, 132068. https://doi.org/10.1016/j.chemosphere.2021.132068." in Chemosphere (2022).

Rosemary essential oils as a promising source of bioactive compounds: Chemical composition, thermal properties, biological activity, and gastronomical perspectives

Micić, Darko; Ðurović, Saša; Riabov, Pavel; Tomić, Ana; Šovljanski, Olja; Filip, Snežana; Tosti, Tomislav; Dojčinović, Biljana; Božović, Rade; Jovanović, Dušan; Blagojević, Stevan

(Switzerland : Multidisciplinary Digital Publishing Institute (MDPI), 2021)

TY  - DATA
AU  - Micić, Darko
AU  - Ðurović, Saša
AU  - Riabov, Pavel
AU  - Tomić, Ana
AU  - Šovljanski, Olja
AU  - Filip, Snežana
AU  - Tosti, Tomislav
AU  - Dojčinović, Biljana
AU  - Božović, Rade
AU  - Jovanović, Dušan
AU  - Blagojević, Stevan
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4793
PB  - Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)
T2  - Foods
T1  - Rosemary essential oils as a promising source of bioactive compounds: Chemical composition, thermal properties, biological activity, and gastronomical perspectives
DO  - 10.3390/foods10112734
ER  - 
@misc{
author = "Micić, Darko and Ðurović, Saša and Riabov, Pavel and Tomić, Ana and Šovljanski, Olja and Filip, Snežana and Tosti, Tomislav and Dojčinović, Biljana and Božović, Rade and Jovanović, Dušan and Blagojević, Stevan",
year = "2021",
publisher = "Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)",
journal = "Foods",
title = "Rosemary essential oils as a promising source of bioactive compounds: Chemical composition, thermal properties, biological activity, and gastronomical perspectives",
doi = "10.3390/foods10112734"
}
Micić, D., Ðurović, S., Riabov, P., Tomić, A., Šovljanski, O., Filip, S., Tosti, T., Dojčinović, B., Božović, R., Jovanović, D.,& Blagojević, S.. (2021). Rosemary essential oils as a promising source of bioactive compounds: Chemical composition, thermal properties, biological activity, and gastronomical perspectives. in Foods
Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)..
https://doi.org/10.3390/foods10112734
Micić D, Ðurović S, Riabov P, Tomić A, Šovljanski O, Filip S, Tosti T, Dojčinović B, Božović R, Jovanović D, Blagojević S. Rosemary essential oils as a promising source of bioactive compounds: Chemical composition, thermal properties, biological activity, and gastronomical perspectives. in Foods. 2021;.
doi:10.3390/foods10112734 .
Micić, Darko, Ðurović, Saša, Riabov, Pavel, Tomić, Ana, Šovljanski, Olja, Filip, Snežana, Tosti, Tomislav, Dojčinović, Biljana, Božović, Rade, Jovanović, Dušan, Blagojević, Stevan, "Rosemary essential oils as a promising source of bioactive compounds: Chemical composition, thermal properties, biological activity, and gastronomical perspectives" in Foods (2021),
https://doi.org/10.3390/foods10112734 . .

Rosemary essential oils as a promising source of bioactive compounds: Chemical composition, thermal properties, biological activity, and gastronomical perspectives

Micić, Darko; Ðurović, Saša; Riabov, Pavel; Tomić, Ana; Šovljanski, Olja; Filip, Snežana; Tosti, Tomislav; Dojčinović, Biljana; Božović, Rade; Jovanović, Dušan; Blagojević, Stevan

(Switzerland : Multidisciplinary Digital Publishing Institute (MDPI), 2021)

TY  - JOUR
AU  - Micić, Darko
AU  - Ðurović, Saša
AU  - Riabov, Pavel
AU  - Tomić, Ana
AU  - Šovljanski, Olja
AU  - Filip, Snežana
AU  - Tosti, Tomislav
AU  - Dojčinović, Biljana
AU  - Božović, Rade
AU  - Jovanović, Dušan
AU  - Blagojević, Stevan
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4792
AB  - Rosemary (Rosmarinus officinalis L.) is a plant worldwide cultivated mainly for essential oils, extracts, and as a spice. Up-to-date results showed diversity in composition of the essential oils, which may influence their quality, biological activity, and thermal properties. Therefore, the aim of this study was to investigate the chemical composition, antimicrobial activity, and thermal properties of the rosemary essential oils originating from Serbia and Russia. Additionally, oils were added to the sunflower oils in order to investigate possible antioxidant activity during the frying. Investigation of the chemical profile marked α-pinene, eucalyptol, and camphor as the most abundant compounds in both oils. However, overall composition influenced in such manner that Russian oil showed significantly higher antimicrobial activity, while Serbian oil proved to be better antioxidant agent in case of frying of sunflower oil. This would significantly influence possible application of the oils, which could be used as an antioxidant agent for extension of the food shelf life, or antimicrobial agent for protection against different microbial strains.
PB  - Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)
T2  - Foods
T1  - Rosemary essential oils as a promising source of bioactive compounds: Chemical composition, thermal properties, biological activity, and gastronomical perspectives
VL  - 10
IS  - 11
SP  - 2734
DO  - 10.3390/foods10112734
ER  - 
@article{
author = "Micić, Darko and Ðurović, Saša and Riabov, Pavel and Tomić, Ana and Šovljanski, Olja and Filip, Snežana and Tosti, Tomislav and Dojčinović, Biljana and Božović, Rade and Jovanović, Dušan and Blagojević, Stevan",
year = "2021",
abstract = "Rosemary (Rosmarinus officinalis L.) is a plant worldwide cultivated mainly for essential oils, extracts, and as a spice. Up-to-date results showed diversity in composition of the essential oils, which may influence their quality, biological activity, and thermal properties. Therefore, the aim of this study was to investigate the chemical composition, antimicrobial activity, and thermal properties of the rosemary essential oils originating from Serbia and Russia. Additionally, oils were added to the sunflower oils in order to investigate possible antioxidant activity during the frying. Investigation of the chemical profile marked α-pinene, eucalyptol, and camphor as the most abundant compounds in both oils. However, overall composition influenced in such manner that Russian oil showed significantly higher antimicrobial activity, while Serbian oil proved to be better antioxidant agent in case of frying of sunflower oil. This would significantly influence possible application of the oils, which could be used as an antioxidant agent for extension of the food shelf life, or antimicrobial agent for protection against different microbial strains.",
publisher = "Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)",
journal = "Foods",
title = "Rosemary essential oils as a promising source of bioactive compounds: Chemical composition, thermal properties, biological activity, and gastronomical perspectives",
volume = "10",
number = "11",
pages = "2734",
doi = "10.3390/foods10112734"
}
Micić, D., Ðurović, S., Riabov, P., Tomić, A., Šovljanski, O., Filip, S., Tosti, T., Dojčinović, B., Božović, R., Jovanović, D.,& Blagojević, S.. (2021). Rosemary essential oils as a promising source of bioactive compounds: Chemical composition, thermal properties, biological activity, and gastronomical perspectives. in Foods
Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)., 10(11), 2734.
https://doi.org/10.3390/foods10112734
Micić D, Ðurović S, Riabov P, Tomić A, Šovljanski O, Filip S, Tosti T, Dojčinović B, Božović R, Jovanović D, Blagojević S. Rosemary essential oils as a promising source of bioactive compounds: Chemical composition, thermal properties, biological activity, and gastronomical perspectives. in Foods. 2021;10(11):2734.
doi:10.3390/foods10112734 .
Micić, Darko, Ðurović, Saša, Riabov, Pavel, Tomić, Ana, Šovljanski, Olja, Filip, Snežana, Tosti, Tomislav, Dojčinović, Biljana, Božović, Rade, Jovanović, Dušan, Blagojević, Stevan, "Rosemary essential oils as a promising source of bioactive compounds: Chemical composition, thermal properties, biological activity, and gastronomical perspectives" in Foods, 10, no. 11 (2021):2734,
https://doi.org/10.3390/foods10112734 . .

Significant Stacking Interactions of Resonance-Assisted Hydrogen-Bridged (RAHB) Rings at Large Horizontal Displacements

Blagojević Filipović, Jelena P.; Zarić, Snežana D.

(American Chemical Society, 2021)

TY  - JOUR
AU  - Blagojević Filipović, Jelena P.
AU  - Zarić, Snežana D.
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4790
AB  - The stacking contacts between two resonance-assisted hydrogen-bridged (RAHB) rings and stacking contacts between RAHB rings and C6-aromatic groups are frequently found at large horizontal displacements in the crystal structures found in the Cambridge Structural Database (CSD), particularly in the range of 4.0–6.0 and 5.5–6.5 Å, respectively. Ab initio calculations reveal that interactions at large offsets, although weaker than interactions at smaller offsets, can be significant, since a large portion of interaction energy (in some systems up to 66%) can be preserved upon shifting to larger offset values.
PB  - American Chemical Society
T2  - Crystal Growth & Design
T1  - Significant Stacking Interactions of Resonance-Assisted Hydrogen-Bridged (RAHB) Rings at Large Horizontal Displacements
VL  - 21
IS  - 9
SP  - 4947
EP  - 4958
DO  - 10.1021/acs.cgd.1c00392
ER  - 
@article{
author = "Blagojević Filipović, Jelena P. and Zarić, Snežana D.",
year = "2021",
abstract = "The stacking contacts between two resonance-assisted hydrogen-bridged (RAHB) rings and stacking contacts between RAHB rings and C6-aromatic groups are frequently found at large horizontal displacements in the crystal structures found in the Cambridge Structural Database (CSD), particularly in the range of 4.0–6.0 and 5.5–6.5 Å, respectively. Ab initio calculations reveal that interactions at large offsets, although weaker than interactions at smaller offsets, can be significant, since a large portion of interaction energy (in some systems up to 66%) can be preserved upon shifting to larger offset values.",
publisher = "American Chemical Society",
journal = "Crystal Growth & Design",
title = "Significant Stacking Interactions of Resonance-Assisted Hydrogen-Bridged (RAHB) Rings at Large Horizontal Displacements",
volume = "21",
number = "9",
pages = "4947-4958",
doi = "10.1021/acs.cgd.1c00392"
}
Blagojević Filipović, J. P.,& Zarić, S. D.. (2021). Significant Stacking Interactions of Resonance-Assisted Hydrogen-Bridged (RAHB) Rings at Large Horizontal Displacements. in Crystal Growth & Design
American Chemical Society., 21(9), 4947-4958.
https://doi.org/10.1021/acs.cgd.1c00392
Blagojević Filipović JP, Zarić SD. Significant Stacking Interactions of Resonance-Assisted Hydrogen-Bridged (RAHB) Rings at Large Horizontal Displacements. in Crystal Growth & Design. 2021;21(9):4947-4958.
doi:10.1021/acs.cgd.1c00392 .
Blagojević Filipović, Jelena P., Zarić, Snežana D., "Significant Stacking Interactions of Resonance-Assisted Hydrogen-Bridged (RAHB) Rings at Large Horizontal Displacements" in Crystal Growth & Design, 21, no. 9 (2021):4947-4958,
https://doi.org/10.1021/acs.cgd.1c00392 . .

Supplementary data for the article: Margetić, A.; Stojanović, S.; Ristović, M.; Vujčić, Z.; Dojnov, B. Fungal Oxidative and Hydrolyzing Enzymes as Designers in the Biological Production of Dietary Fibers from Triticale. LWT 2021, 145, 111291. https://doi.org/10.1016/j.lwt.2021.111291.

Margetić, Aleksandra; Stojanović, Sanja; Ristović, Marina; Vujčić, Zoran; Dojnov, Biljana

(Elsevier, 2021)

TY  - DATA
AU  - Margetić, Aleksandra
AU  - Stojanović, Sanja
AU  - Ristović, Marina
AU  - Vujčić, Zoran
AU  - Dojnov, Biljana
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4802
PB  - Elsevier
T2  - LWT - Food Science and Technology
T1  - Supplementary data for the article: Margetić, A.; Stojanović, S.; Ristović, M.; Vujčić, Z.; Dojnov, B. Fungal Oxidative and Hydrolyzing Enzymes as Designers in the Biological Production of Dietary Fibers from Triticale. LWT 2021, 145, 111291. https://doi.org/10.1016/j.lwt.2021.111291.
ER  - 
@misc{
author = "Margetić, Aleksandra and Stojanović, Sanja and Ristović, Marina and Vujčić, Zoran and Dojnov, Biljana",
year = "2021",
publisher = "Elsevier",
journal = "LWT - Food Science and Technology",
title = "Supplementary data for the article: Margetić, A.; Stojanović, S.; Ristović, M.; Vujčić, Z.; Dojnov, B. Fungal Oxidative and Hydrolyzing Enzymes as Designers in the Biological Production of Dietary Fibers from Triticale. LWT 2021, 145, 111291. https://doi.org/10.1016/j.lwt.2021.111291."
}
Margetić, A., Stojanović, S., Ristović, M., Vujčić, Z.,& Dojnov, B.. (2021). Supplementary data for the article: Margetić, A.; Stojanović, S.; Ristović, M.; Vujčić, Z.; Dojnov, B. Fungal Oxidative and Hydrolyzing Enzymes as Designers in the Biological Production of Dietary Fibers from Triticale. LWT 2021, 145, 111291. https://doi.org/10.1016/j.lwt.2021.111291.. in LWT - Food Science and Technology
Elsevier..
Margetić A, Stojanović S, Ristović M, Vujčić Z, Dojnov B. Supplementary data for the article: Margetić, A.; Stojanović, S.; Ristović, M.; Vujčić, Z.; Dojnov, B. Fungal Oxidative and Hydrolyzing Enzymes as Designers in the Biological Production of Dietary Fibers from Triticale. LWT 2021, 145, 111291. https://doi.org/10.1016/j.lwt.2021.111291.. in LWT - Food Science and Technology. 2021;..
Margetić, Aleksandra, Stojanović, Sanja, Ristović, Marina, Vujčić, Zoran, Dojnov, Biljana, "Supplementary data for the article: Margetić, A.; Stojanović, S.; Ristović, M.; Vujčić, Z.; Dojnov, B. Fungal Oxidative and Hydrolyzing Enzymes as Designers in the Biological Production of Dietary Fibers from Triticale. LWT 2021, 145, 111291. https://doi.org/10.1016/j.lwt.2021.111291." in LWT - Food Science and Technology (2021).

Fungal oxidative and hydrolyzing enzymes as designers in the biological production of dietary fibers from triticale

Margetić, Aleksandra; Stojanović, Sanja; Ristović, Marina; Vujčić, Zoran; Dojnov, Biljana

(Elsevier, 2021)

TY  - JOUR
AU  - Margetić, Aleksandra
AU  - Stojanović, Sanja
AU  - Ristović, Marina
AU  - Vujčić, Zoran
AU  - Dojnov, Biljana
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4801
AB  - There is an urgent need to increase the daily intake of insoluble dietary fiber, and at the same time to find new sources and new production technologies. We hypothesized that fungal enzymes directly involved in lignocellulosic material hydrolysis (Aspergillus and Trichoderma enzyme cocktails) will change the fiber structure particularly efficiently after the action of laccase (Trametes versicolor enzyme cocktail). Enzymes production on an inducing substrate (same as starting material for obtainment of insoluble dietary fibers) and their usage resulted in obtainment of novel insoluble dietary fibers with better characteristics, 24% higher swelling, 43% higher WRC and 57% higher ORC compared to insoluble dietary fibers from triticale (already proven to be a good food additive). Changes in structure were analyzed by FTIR and microscopic analysis. Antioxidative performance of the obtained products, new insoluble and released soluble dietary fibers, was analyzed in detail. Newly obtained soluble dietary fibers demonstrated up to 20 times higher antioxidant activity compared to untreated fibers (ABTS and DPPH tests). These results suggest their good performance as a future food additive. At the same time, they prove the hypothesis that the use of enzyme cocktails rich in laccase is a good choice for biological pretreatment in this process.
PB  - Elsevier
T2  - LWT - Food Science and Technology
T1  - Fungal oxidative and hydrolyzing enzymes as designers in the biological production of dietary fibers from triticale
VL  - 145
SP  - 111291
DO  - 10.1016/j.lwt.2021.111291
ER  - 
@article{
author = "Margetić, Aleksandra and Stojanović, Sanja and Ristović, Marina and Vujčić, Zoran and Dojnov, Biljana",
year = "2021",
abstract = "There is an urgent need to increase the daily intake of insoluble dietary fiber, and at the same time to find new sources and new production technologies. We hypothesized that fungal enzymes directly involved in lignocellulosic material hydrolysis (Aspergillus and Trichoderma enzyme cocktails) will change the fiber structure particularly efficiently after the action of laccase (Trametes versicolor enzyme cocktail). Enzymes production on an inducing substrate (same as starting material for obtainment of insoluble dietary fibers) and their usage resulted in obtainment of novel insoluble dietary fibers with better characteristics, 24% higher swelling, 43% higher WRC and 57% higher ORC compared to insoluble dietary fibers from triticale (already proven to be a good food additive). Changes in structure were analyzed by FTIR and microscopic analysis. Antioxidative performance of the obtained products, new insoluble and released soluble dietary fibers, was analyzed in detail. Newly obtained soluble dietary fibers demonstrated up to 20 times higher antioxidant activity compared to untreated fibers (ABTS and DPPH tests). These results suggest their good performance as a future food additive. At the same time, they prove the hypothesis that the use of enzyme cocktails rich in laccase is a good choice for biological pretreatment in this process.",
publisher = "Elsevier",
journal = "LWT - Food Science and Technology",
title = "Fungal oxidative and hydrolyzing enzymes as designers in the biological production of dietary fibers from triticale",
volume = "145",
pages = "111291",
doi = "10.1016/j.lwt.2021.111291"
}
Margetić, A., Stojanović, S., Ristović, M., Vujčić, Z.,& Dojnov, B.. (2021). Fungal oxidative and hydrolyzing enzymes as designers in the biological production of dietary fibers from triticale. in LWT - Food Science and Technology
Elsevier., 145, 111291.
https://doi.org/10.1016/j.lwt.2021.111291
Margetić A, Stojanović S, Ristović M, Vujčić Z, Dojnov B. Fungal oxidative and hydrolyzing enzymes as designers in the biological production of dietary fibers from triticale. in LWT - Food Science and Technology. 2021;145:111291.
doi:10.1016/j.lwt.2021.111291 .
Margetić, Aleksandra, Stojanović, Sanja, Ristović, Marina, Vujčić, Zoran, Dojnov, Biljana, "Fungal oxidative and hydrolyzing enzymes as designers in the biological production of dietary fibers from triticale" in LWT - Food Science and Technology, 145 (2021):111291,
https://doi.org/10.1016/j.lwt.2021.111291 . .

Recombinant Bet v 1-BanLec chimera modulates functional characteristics of peritoneal murine macrophages by promoting IL-10 secretion

Protić-Rosić, Isidora; Nešić, Andrijana; Lukić, Ivana; Miljković, Radmila; Popović, Dragan M.; Atanasković-Marković, Marina; Stojanović, Marijana; Gavrović-Jankulović, Marija

(Elsevier, 2021)

TY  - JOUR
AU  - Protić-Rosić, Isidora
AU  - Nešić, Andrijana
AU  - Lukić, Ivana
AU  - Miljković, Radmila
AU  - Popović, Dragan M.
AU  - Atanasković-Marković, Marina
AU  - Stojanović, Marijana
AU  - Gavrović-Jankulović, Marija
PY  - 2021
UR  - https://www.sciencedirect.com/science/article/pii/S0161589021001905
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4604
AB  - Allergen-specific immunotherapy (AIT) is a desensitizing treatment for allergic diseases that corrects the underlined pathological immune response to innocuous protein antigens, called allergens. Recombinant allergens employed in the AIT allowed the production of well-defined formulations that possessed consistent quality but were often less efficient than natural allergen extracts. Combining recombinant allergens with an adjuvant or immunomodulatory agent could improve AIT efficacy. This study aimed to perform structural and functional characterization of newly designed recombinant chimera composed of the Bet v 1, the major birch pollen allergen, and Banana Lectin (BanLec), TLR2, and CD14 binding protein, for the application in AIT. rBet v 1-BanLec chimera was designed in silico and expressed as a soluble fraction in Escherichia coli. Purified rBet v 1-BanLec (33.4 kDa) retained BanLec-associated biological activity of carbohydrate-binding and preserved IgE reactive epitopes of Bet v 1. The chimera revealed secondary structures with predominant β sheets. The immunomodulatory capacity of rBet v 1-BanLec tested on macrophages showed changes in myeloperoxidase activity, reduced NO production, and significant alterations in the production of cytokines when compared to both rBanLec and rBet v 1. Comparing to rBet v 1, rBet v 1-BanLec was demonstrated to be more efficient promoter of IL-10 production as well as weaker inducer of NO production and secretion of pro-inflammatory cytokines TNFα, and IL-6. The ability of rBet v 1-BanLec to promote IL-10 in together with the preserved 3D structure of Bet v 1 part implies that the construct might exert a beneficial effect in the allergen-specific immunotherapy.
PB  - Elsevier
T2  - Molecular Immunology
T2  - Molecular ImmunologyMolecular Immunology
T1  - Recombinant Bet v 1-BanLec chimera modulates functional characteristics of peritoneal murine macrophages by promoting IL-10 secretion
VL  - 138
SP  - 58
EP  - 67
DO  - 10.1016/j.molimm.2021.06.015
ER  - 
@article{
author = "Protić-Rosić, Isidora and Nešić, Andrijana and Lukić, Ivana and Miljković, Radmila and Popović, Dragan M. and Atanasković-Marković, Marina and Stojanović, Marijana and Gavrović-Jankulović, Marija",
year = "2021",
abstract = "Allergen-specific immunotherapy (AIT) is a desensitizing treatment for allergic diseases that corrects the underlined pathological immune response to innocuous protein antigens, called allergens. Recombinant allergens employed in the AIT allowed the production of well-defined formulations that possessed consistent quality but were often less efficient than natural allergen extracts. Combining recombinant allergens with an adjuvant or immunomodulatory agent could improve AIT efficacy. This study aimed to perform structural and functional characterization of newly designed recombinant chimera composed of the Bet v 1, the major birch pollen allergen, and Banana Lectin (BanLec), TLR2, and CD14 binding protein, for the application in AIT. rBet v 1-BanLec chimera was designed in silico and expressed as a soluble fraction in Escherichia coli. Purified rBet v 1-BanLec (33.4 kDa) retained BanLec-associated biological activity of carbohydrate-binding and preserved IgE reactive epitopes of Bet v 1. The chimera revealed secondary structures with predominant β sheets. The immunomodulatory capacity of rBet v 1-BanLec tested on macrophages showed changes in myeloperoxidase activity, reduced NO production, and significant alterations in the production of cytokines when compared to both rBanLec and rBet v 1. Comparing to rBet v 1, rBet v 1-BanLec was demonstrated to be more efficient promoter of IL-10 production as well as weaker inducer of NO production and secretion of pro-inflammatory cytokines TNFα, and IL-6. The ability of rBet v 1-BanLec to promote IL-10 in together with the preserved 3D structure of Bet v 1 part implies that the construct might exert a beneficial effect in the allergen-specific immunotherapy.",
publisher = "Elsevier",
journal = "Molecular Immunology, Molecular ImmunologyMolecular Immunology",
title = "Recombinant Bet v 1-BanLec chimera modulates functional characteristics of peritoneal murine macrophages by promoting IL-10 secretion",
volume = "138",
pages = "58-67",
doi = "10.1016/j.molimm.2021.06.015"
}
Protić-Rosić, I., Nešić, A., Lukić, I., Miljković, R., Popović, D. M., Atanasković-Marković, M., Stojanović, M.,& Gavrović-Jankulović, M.. (2021). Recombinant Bet v 1-BanLec chimera modulates functional characteristics of peritoneal murine macrophages by promoting IL-10 secretion. in Molecular Immunology
Elsevier., 138, 58-67.
https://doi.org/10.1016/j.molimm.2021.06.015
Protić-Rosić I, Nešić A, Lukić I, Miljković R, Popović DM, Atanasković-Marković M, Stojanović M, Gavrović-Jankulović M. Recombinant Bet v 1-BanLec chimera modulates functional characteristics of peritoneal murine macrophages by promoting IL-10 secretion. in Molecular Immunology. 2021;138:58-67.
doi:10.1016/j.molimm.2021.06.015 .
Protić-Rosić, Isidora, Nešić, Andrijana, Lukić, Ivana, Miljković, Radmila, Popović, Dragan M., Atanasković-Marković, Marina, Stojanović, Marijana, Gavrović-Jankulović, Marija, "Recombinant Bet v 1-BanLec chimera modulates functional characteristics of peritoneal murine macrophages by promoting IL-10 secretion" in Molecular Immunology, 138 (2021):58-67,
https://doi.org/10.1016/j.molimm.2021.06.015 . .

Structural study of Pt(II) and Pd(II) complexes with quinoline-2-carboxaldehyde thiosemicarbazone

Ristić, Predrag; Rodić, Marko V.; Filipović, Nenad R.; Mitić, Dragana; Anđelković, Katarina K.; Todorović, Tamara

(Serbian Chemical Society, 2021)

TY  - JOUR
AU  - Ristić, Predrag
AU  - Rodić, Marko V.
AU  - Filipović, Nenad R.
AU  - Mitić, Dragana
AU  - Anđelković, Katarina K.
AU  - Todorović, Tamara
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4789
AB  - Two square-planar complexes, [PtLCl] (1) and [PdLCl] (2), were synthesized with quinoline-2-carboxaldehyde thiosemicarbazone ligand (HL), and characterized by IR and NMR spectroscopy and single crystal X-ray diffraction analysis. In both complexes, L- is coordinated tridentately via the same donor atom set, while the fourth coordination site is occupied by a chloride ion. However, the complexes are not isostructural due to different types of non-covalent intermolecular interactions. These interactions were analyzed using Hirshfeld surfaces and two-dimensional fingerprint plots.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Structural study of Pt(II) and Pd(II) complexes with quinoline-2-carboxaldehyde thiosemicarbazone
VL  - 86
IS  - 4
SP  - 393
EP  - 406
DO  - 10.2298/JSC201126079R
ER  - 
@article{
author = "Ristić, Predrag and Rodić, Marko V. and Filipović, Nenad R. and Mitić, Dragana and Anđelković, Katarina K. and Todorović, Tamara",
year = "2021",
abstract = "Two square-planar complexes, [PtLCl] (1) and [PdLCl] (2), were synthesized with quinoline-2-carboxaldehyde thiosemicarbazone ligand (HL), and characterized by IR and NMR spectroscopy and single crystal X-ray diffraction analysis. In both complexes, L- is coordinated tridentately via the same donor atom set, while the fourth coordination site is occupied by a chloride ion. However, the complexes are not isostructural due to different types of non-covalent intermolecular interactions. These interactions were analyzed using Hirshfeld surfaces and two-dimensional fingerprint plots.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Structural study of Pt(II) and Pd(II) complexes with quinoline-2-carboxaldehyde thiosemicarbazone",
volume = "86",
number = "4",
pages = "393-406",
doi = "10.2298/JSC201126079R"
}
Ristić, P., Rodić, M. V., Filipović, N. R., Mitić, D., Anđelković, K. K.,& Todorović, T.. (2021). Structural study of Pt(II) and Pd(II) complexes with quinoline-2-carboxaldehyde thiosemicarbazone. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 86(4), 393-406.
https://doi.org/10.2298/JSC201126079R
Ristić P, Rodić MV, Filipović NR, Mitić D, Anđelković KK, Todorović T. Structural study of Pt(II) and Pd(II) complexes with quinoline-2-carboxaldehyde thiosemicarbazone. in Journal of the Serbian Chemical Society. 2021;86(4):393-406.
doi:10.2298/JSC201126079R .
Ristić, Predrag, Rodić, Marko V., Filipović, Nenad R., Mitić, Dragana, Anđelković, Katarina K., Todorović, Tamara, "Structural study of Pt(II) and Pd(II) complexes with quinoline-2-carboxaldehyde thiosemicarbazone" in Journal of the Serbian Chemical Society, 86, no. 4 (2021):393-406,
https://doi.org/10.2298/JSC201126079R . .
1
1

Synthesis, characterization and biological activity of Pt(II) complexes with steroidal thiosemicarbazones

Čobeljić, Božidar; Živković, Marijana B.; Matić, Ivana Z.; Novaković, Irena T.; Sladić, Dušan M.; Anđelković, Katarina K.; Krstić, Natalija M.

(Serbian Chemical Society, 2021)

TY  - JOUR
AU  - Čobeljić, Božidar
AU  - Živković, Marijana B.
AU  - Matić, Ivana Z.
AU  - Novaković, Irena T.
AU  - Sladić, Dušan M.
AU  - Anđelković, Katarina K.
AU  - Krstić, Natalija M.
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4788
AB  - In this work, Pt(II) complexes of previously synthesized steroidal thiosemicarbazones were synthesized and characterized. The ligands and their metal complexes were studied by analytical and spectroscopic data (elemental analysis, IR, 1D-NMR and 2D-NMR, HSQC, HMBC, NOESY, COSY), the analysis of which enabled complete 1H and 13C assignments of each compound including E and Z isomers. All the synthesized ligands and complexes were screened for their cytotoxic and antimicrobial activity. The results demonstrate that the new steroidal thiosemicarbazone complexes were significantly less cytotoxic than the corresponding steroidal thiosemicarbazones. In addition, complexes showed lower antimicrobial activity than the standard drugs, similar to the activity of the starting thiosemicarbazones.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Synthesis, characterization and biological activity of Pt(II) complexes with steroidal thiosemicarbazones
VL  - 86
IS  - 5
SP  - 459
EP  - 468
ER  - 
@article{
author = "Čobeljić, Božidar and Živković, Marijana B. and Matić, Ivana Z. and Novaković, Irena T. and Sladić, Dušan M. and Anđelković, Katarina K. and Krstić, Natalija M.",
year = "2021",
abstract = "In this work, Pt(II) complexes of previously synthesized steroidal thiosemicarbazones were synthesized and characterized. The ligands and their metal complexes were studied by analytical and spectroscopic data (elemental analysis, IR, 1D-NMR and 2D-NMR, HSQC, HMBC, NOESY, COSY), the analysis of which enabled complete 1H and 13C assignments of each compound including E and Z isomers. All the synthesized ligands and complexes were screened for their cytotoxic and antimicrobial activity. The results demonstrate that the new steroidal thiosemicarbazone complexes were significantly less cytotoxic than the corresponding steroidal thiosemicarbazones. In addition, complexes showed lower antimicrobial activity than the standard drugs, similar to the activity of the starting thiosemicarbazones.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Synthesis, characterization and biological activity of Pt(II) complexes with steroidal thiosemicarbazones",
volume = "86",
number = "5",
pages = "459-468"
}
Čobeljić, B., Živković, M. B., Matić, I. Z., Novaković, I. T., Sladić, D. M., Anđelković, K. K.,& Krstić, N. M.. (2021). Synthesis, characterization and biological activity of Pt(II) complexes with steroidal thiosemicarbazones. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 86(5), 459-468.
Čobeljić B, Živković MB, Matić IZ, Novaković IT, Sladić DM, Anđelković KK, Krstić NM. Synthesis, characterization and biological activity of Pt(II) complexes with steroidal thiosemicarbazones. in Journal of the Serbian Chemical Society. 2021;86(5):459-468..
Čobeljić, Božidar, Živković, Marijana B., Matić, Ivana Z., Novaković, Irena T., Sladić, Dušan M., Anđelković, Katarina K., Krstić, Natalija M., "Synthesis, characterization and biological activity of Pt(II) complexes with steroidal thiosemicarbazones" in Journal of the Serbian Chemical Society, 86, no. 5 (2021):459-468.

Structural, antioxidant, antiproliferative and in‒silico study of pyridine-based hydrazonyl‒selenazoles and their sulphur isosteres

Araškov, Jovana B.; Nikolić, Milan; Armaković, Stevan; Armaković, Sanja; Rodić, Marko; Višnjevac, Aleksandar; Padrón, José M.; Todorović, Tamara ; Filipović, Nenad R.

(Elsevier, 2021)

TY  - JOUR
AU  - Araškov, Jovana B.
AU  - Nikolić, Milan
AU  - Armaković, Stevan
AU  - Armaković, Sanja
AU  - Rodić, Marko
AU  - Višnjevac, Aleksandar
AU  - Padrón, José M.
AU  - Todorović, Tamara 
AU  - Filipović, Nenad R.
PY  - 2021
UR  - https://www.sciencedirect.com/science/article/pii/S0022286021006451
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4539
AB  - To evaluate the impact of chalcogen atom type, we performed a comparative study of antioxidant capacity and antiproliferative activity of a focused library of three pyridine-based hydrazonyl-1,3-selenazoles and their sulfur isosteres in five antioxidant assays and in six human solid tumor cell lines, respectively. In-silico calculations were further used to check pharmacokinetic profiles of investigated compounds such as drug-likeness parameters and interaction with water. Generally, selenium compounds appear to be more potent in comparison to sulfur isosteres in the performed essays.
PB  - Elsevier
T2  - Journal of Molecular Structure
T1  - Structural, antioxidant, antiproliferative and in‒silico study of pyridine-based hydrazonyl‒selenazoles and their sulphur isosteres
VL  - 1240
SP  - 130512
DO  - 10.1016/j.molstruc.2021.130512
ER  - 
@article{
author = "Araškov, Jovana B. and Nikolić, Milan and Armaković, Stevan and Armaković, Sanja and Rodić, Marko and Višnjevac, Aleksandar and Padrón, José M. and Todorović, Tamara  and Filipović, Nenad R.",
year = "2021",
abstract = "To evaluate the impact of chalcogen atom type, we performed a comparative study of antioxidant capacity and antiproliferative activity of a focused library of three pyridine-based hydrazonyl-1,3-selenazoles and their sulfur isosteres in five antioxidant assays and in six human solid tumor cell lines, respectively. In-silico calculations were further used to check pharmacokinetic profiles of investigated compounds such as drug-likeness parameters and interaction with water. Generally, selenium compounds appear to be more potent in comparison to sulfur isosteres in the performed essays.",
publisher = "Elsevier",
journal = "Journal of Molecular Structure",
title = "Structural, antioxidant, antiproliferative and in‒silico study of pyridine-based hydrazonyl‒selenazoles and their sulphur isosteres",
volume = "1240",
pages = "130512",
doi = "10.1016/j.molstruc.2021.130512"
}
Araškov, J. B., Nikolić, M., Armaković, S., Armaković, S., Rodić, M., Višnjevac, A., Padrón, J. M., Todorović, T.,& Filipović, N. R.. (2021). Structural, antioxidant, antiproliferative and in‒silico study of pyridine-based hydrazonyl‒selenazoles and their sulphur isosteres. in Journal of Molecular Structure
Elsevier., 1240, 130512.
https://doi.org/10.1016/j.molstruc.2021.130512
Araškov JB, Nikolić M, Armaković S, Armaković S, Rodić M, Višnjevac A, Padrón JM, Todorović T, Filipović NR. Structural, antioxidant, antiproliferative and in‒silico study of pyridine-based hydrazonyl‒selenazoles and their sulphur isosteres. in Journal of Molecular Structure. 2021;1240:130512.
doi:10.1016/j.molstruc.2021.130512 .
Araškov, Jovana B., Nikolić, Milan, Armaković, Stevan, Armaković, Sanja, Rodić, Marko, Višnjevac, Aleksandar, Padrón, José M., Todorović, Tamara , Filipović, Nenad R., "Structural, antioxidant, antiproliferative and in‒silico study of pyridine-based hydrazonyl‒selenazoles and their sulphur isosteres" in Journal of Molecular Structure, 1240 (2021):130512,
https://doi.org/10.1016/j.molstruc.2021.130512 . .
7
1
1

Supplementary data for the article: Araškov, J. B.; Nikolić, M.; Armaković, S.; Armaković, S.; Rodić, M.; Višnjevac, A.; Padrón, J. M.; Todorović, T. R.; Filipović, N. R. Structural, Antioxidant, Antiproliferative and In‒silico Study of Pyridine-Based Hydrazonyl‒selenazoles and Their Sulphur Isosteres. Journal of Molecular Structure 2021, 1240, 130512. https://doi.org/10.1016/j.molstruc.2021.130512.

Araškov, Jovana B.; Nikolić, Milan; Armaković, Stevan; Armaković, Sanja; Rodić, Marko; Višnjevac, Aleksandar; Padrón, José M.; Todorović, Tamara; Filipović, Nenad R.

(Elsevier, 2021)

TY  - DATA
AU  - Araškov, Jovana B.
AU  - Nikolić, Milan
AU  - Armaković, Stevan
AU  - Armaković, Sanja
AU  - Rodić, Marko
AU  - Višnjevac, Aleksandar
AU  - Padrón, José M.
AU  - Todorović, Tamara
AU  - Filipović, Nenad R.
PY  - 2021
UR  - https://www.sciencedirect.com/science/article/pii/S0022286021006451
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4540
PB  - Elsevier
T2  - Journal of Molecular Structure
T1  - Supplementary data for the article: Araškov, J. B.; Nikolić, M.; Armaković, S.; Armaković, S.; Rodić, M.; Višnjevac, A.; Padrón, J. M.; Todorović, T. R.; Filipović, N. R. Structural, Antioxidant, Antiproliferative and In‒silico Study of Pyridine-Based Hydrazonyl‒selenazoles and Their Sulphur Isosteres. Journal of Molecular Structure 2021, 1240, 130512. https://doi.org/10.1016/j.molstruc.2021.130512.
ER  - 
@misc{
author = "Araškov, Jovana B. and Nikolić, Milan and Armaković, Stevan and Armaković, Sanja and Rodić, Marko and Višnjevac, Aleksandar and Padrón, José M. and Todorović, Tamara and Filipović, Nenad R.",
year = "2021",
publisher = "Elsevier",
journal = "Journal of Molecular Structure",
title = "Supplementary data for the article: Araškov, J. B.; Nikolić, M.; Armaković, S.; Armaković, S.; Rodić, M.; Višnjevac, A.; Padrón, J. M.; Todorović, T. R.; Filipović, N. R. Structural, Antioxidant, Antiproliferative and In‒silico Study of Pyridine-Based Hydrazonyl‒selenazoles and Their Sulphur Isosteres. Journal of Molecular Structure 2021, 1240, 130512. https://doi.org/10.1016/j.molstruc.2021.130512."
}
Araškov, J. B., Nikolić, M., Armaković, S., Armaković, S., Rodić, M., Višnjevac, A., Padrón, J. M., Todorović, T.,& Filipović, N. R.. (2021). Supplementary data for the article: Araškov, J. B.; Nikolić, M.; Armaković, S.; Armaković, S.; Rodić, M.; Višnjevac, A.; Padrón, J. M.; Todorović, T. R.; Filipović, N. R. Structural, Antioxidant, Antiproliferative and In‒silico Study of Pyridine-Based Hydrazonyl‒selenazoles and Their Sulphur Isosteres. Journal of Molecular Structure 2021, 1240, 130512. https://doi.org/10.1016/j.molstruc.2021.130512.. in Journal of Molecular Structure
Elsevier..
Araškov JB, Nikolić M, Armaković S, Armaković S, Rodić M, Višnjevac A, Padrón JM, Todorović T, Filipović NR. Supplementary data for the article: Araškov, J. B.; Nikolić, M.; Armaković, S.; Armaković, S.; Rodić, M.; Višnjevac, A.; Padrón, J. M.; Todorović, T. R.; Filipović, N. R. Structural, Antioxidant, Antiproliferative and In‒silico Study of Pyridine-Based Hydrazonyl‒selenazoles and Their Sulphur Isosteres. Journal of Molecular Structure 2021, 1240, 130512. https://doi.org/10.1016/j.molstruc.2021.130512.. in Journal of Molecular Structure. 2021;..
Araškov, Jovana B., Nikolić, Milan, Armaković, Stevan, Armaković, Sanja, Rodić, Marko, Višnjevac, Aleksandar, Padrón, José M., Todorović, Tamara, Filipović, Nenad R., "Supplementary data for the article: Araškov, J. B.; Nikolić, M.; Armaković, S.; Armaković, S.; Rodić, M.; Višnjevac, A.; Padrón, J. M.; Todorović, T. R.; Filipović, N. R. Structural, Antioxidant, Antiproliferative and In‒silico Study of Pyridine-Based Hydrazonyl‒selenazoles and Their Sulphur Isosteres. Journal of Molecular Structure 2021, 1240, 130512. https://doi.org/10.1016/j.molstruc.2021.130512." in Journal of Molecular Structure (2021).

Synthesis, characterization, antimicrobial and cytotoxic activity and DNA-binding properties of d-metal complexes with hydrazones of Girard’s T and P reagents

Stevanović, Nevena; Mazzeo, Paolo Pio; Bacchi, Alessia; Matić, Ivana Z.; Đorđić Crnogorac, Marija; Stanojković, Tatjana; Vujčić, Miroslava; Novaković, Irena T.; Radanović, Dušanka; Šumar-Ristović, Maja; Sladić, Dušan; Čobeljić, Božidar; Anđelković, Katarina K.

(Springer, 2021)

TY  - JOUR
AU  - Stevanović, Nevena
AU  - Mazzeo, Paolo Pio
AU  - Bacchi, Alessia
AU  - Matić, Ivana Z.
AU  - Đorđić Crnogorac, Marija
AU  - Stanojković, Tatjana
AU  - Vujčić, Miroslava
AU  - Novaković, Irena T.
AU  - Radanović, Dušanka
AU  - Šumar-Ristović, Maja
AU  - Sladić, Dušan
AU  - Čobeljić, Božidar
AU  - Anđelković, Katarina K.
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4673
AB  - In this work synthesis, characterization and crystal structures of 1, Zn(II) complex ([ZnL1(NCS)2]), with (E)-1-(2-oxo-2-(2-(quinolin-2-ylmethylene)hydrazinyl)ethyl)pyridin-1-ium chloride (HL1Cl) and 2, Bi(III) complex ([BiHL2Cl4] × 1/2CH3OH), with (E)-N,N,N-trimethyl-2-oxo-2-(2-(1-(thiazol-2-yl)ethylidene)hydrazinyl)ethan-1-aminium chloride (HL2Cl), have been reported. Zn(II) complex possesses a distorted trigonal bipyramidal geometry while surroundings around Bi(III) ion are extended pentagonal bipyramidal. Antimicrobial activity, brine shrimp assay and DPPH radical scavenging activity of both complexes, including previously synthesized complexes with HL2Cl ligand (Zn(II) and Ni(II)) and complexes with (E)-N,N,N-trimethyl-2-oxo-2-(2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)ethan-1-aminium chloride (HL3Cl) (Zn(II), Cu(II), Cd(II), Co(II), Fe(III), Ni(II)), were evaluated. For the most active complexes, cytotoxic activity against five malignant cancer cell lines (HeLa, A375, MCF7, PC-3 and A549) and normal cell line HaCaT, as well as generation of reactive oxygen species (ROS), was tested.
PB  - Springer
T2  - JBIC Journal of Biological Inorganic Chemistry
T1  - Synthesis, characterization, antimicrobial and cytotoxic activity and DNA-binding properties of d-metal complexes with hydrazones of Girard’s T and P reagents
VL  - 26
SP  - 863
EP  - 880
DO  - 10.1007/s00775-021-01893-5
ER  - 
@article{
author = "Stevanović, Nevena and Mazzeo, Paolo Pio and Bacchi, Alessia and Matić, Ivana Z. and Đorđić Crnogorac, Marija and Stanojković, Tatjana and Vujčić, Miroslava and Novaković, Irena T. and Radanović, Dušanka and Šumar-Ristović, Maja and Sladić, Dušan and Čobeljić, Božidar and Anđelković, Katarina K.",
year = "2021",
abstract = "In this work synthesis, characterization and crystal structures of 1, Zn(II) complex ([ZnL1(NCS)2]), with (E)-1-(2-oxo-2-(2-(quinolin-2-ylmethylene)hydrazinyl)ethyl)pyridin-1-ium chloride (HL1Cl) and 2, Bi(III) complex ([BiHL2Cl4] × 1/2CH3OH), with (E)-N,N,N-trimethyl-2-oxo-2-(2-(1-(thiazol-2-yl)ethylidene)hydrazinyl)ethan-1-aminium chloride (HL2Cl), have been reported. Zn(II) complex possesses a distorted trigonal bipyramidal geometry while surroundings around Bi(III) ion are extended pentagonal bipyramidal. Antimicrobial activity, brine shrimp assay and DPPH radical scavenging activity of both complexes, including previously synthesized complexes with HL2Cl ligand (Zn(II) and Ni(II)) and complexes with (E)-N,N,N-trimethyl-2-oxo-2-(2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)ethan-1-aminium chloride (HL3Cl) (Zn(II), Cu(II), Cd(II), Co(II), Fe(III), Ni(II)), were evaluated. For the most active complexes, cytotoxic activity against five malignant cancer cell lines (HeLa, A375, MCF7, PC-3 and A549) and normal cell line HaCaT, as well as generation of reactive oxygen species (ROS), was tested.",
publisher = "Springer",
journal = "JBIC Journal of Biological Inorganic Chemistry",
title = "Synthesis, characterization, antimicrobial and cytotoxic activity and DNA-binding properties of d-metal complexes with hydrazones of Girard’s T and P reagents",
volume = "26",
pages = "863-880",
doi = "10.1007/s00775-021-01893-5"
}
Stevanović, N., Mazzeo, P. P., Bacchi, A., Matić, I. Z., Đorđić Crnogorac, M., Stanojković, T., Vujčić, M., Novaković, I. T., Radanović, D., Šumar-Ristović, M., Sladić, D., Čobeljić, B.,& Anđelković, K. K.. (2021). Synthesis, characterization, antimicrobial and cytotoxic activity and DNA-binding properties of d-metal complexes with hydrazones of Girard’s T and P reagents. in JBIC Journal of Biological Inorganic Chemistry
Springer., 26, 863-880.
https://doi.org/10.1007/s00775-021-01893-5
Stevanović N, Mazzeo PP, Bacchi A, Matić IZ, Đorđić Crnogorac M, Stanojković T, Vujčić M, Novaković IT, Radanović D, Šumar-Ristović M, Sladić D, Čobeljić B, Anđelković KK. Synthesis, characterization, antimicrobial and cytotoxic activity and DNA-binding properties of d-metal complexes with hydrazones of Girard’s T and P reagents. in JBIC Journal of Biological Inorganic Chemistry. 2021;26:863-880.
doi:10.1007/s00775-021-01893-5 .
Stevanović, Nevena, Mazzeo, Paolo Pio, Bacchi, Alessia, Matić, Ivana Z., Đorđić Crnogorac, Marija, Stanojković, Tatjana, Vujčić, Miroslava, Novaković, Irena T., Radanović, Dušanka, Šumar-Ristović, Maja, Sladić, Dušan, Čobeljić, Božidar, Anđelković, Katarina K., "Synthesis, characterization, antimicrobial and cytotoxic activity and DNA-binding properties of d-metal complexes with hydrazones of Girard’s T and P reagents" in JBIC Journal of Biological Inorganic Chemistry, 26 (2021):863-880,
https://doi.org/10.1007/s00775-021-01893-5 . .

Supplementary data for the article: Stevanović, N.; Mazzeo, P. P.; Bacchi, A.; Matić, I. Z.; Đorđić Crnogorac, M.; Stanojković, T.; Vujčić, M.; Novaković, I.; Radanović, D.; Šumar-Ristović, M.; Sladić, D.; Čobeljić, B.; Anđelković, K. Synthesis, Characterization, Antimicrobial and Cytotoxic Activity and DNA-Binding Properties of d-Metal Complexes with Hydrazones of Girard’s T and P Reagents. J Biol Inorg Chem 2021. https://doi.org/10.1007/s00775-021-01893-5.

Stevanović, Nevena; Mazzeo, Paolo Pio; Bacchi, Alessia; Matić, Ivana Z.; Đorđić Crnogorac, Marija; Stanojković, Tatjana; Vujčić, Miroslava; Novaković, Irena T.; Radanović, Dušanka; Šumar-Ristović, Maja; Sladić, Dušan; Čobeljić, Božidar; Anđelković, Katarina K.

(Springer, 2021)

TY  - DATA
AU  - Stevanović, Nevena
AU  - Mazzeo, Paolo Pio
AU  - Bacchi, Alessia
AU  - Matić, Ivana Z.
AU  - Đorđić Crnogorac, Marija
AU  - Stanojković, Tatjana
AU  - Vujčić, Miroslava
AU  - Novaković, Irena T.
AU  - Radanović, Dušanka
AU  - Šumar-Ristović, Maja
AU  - Sladić, Dušan
AU  - Čobeljić, Božidar
AU  - Anđelković, Katarina K.
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4675
AB  - In this work synthesis, characterization and crystal structures of 1, Zn(II) complex ([ZnL1(NCS)2]), with (E)-1-(2-oxo-2-(2-(quinolin-2-ylmethylene)hydrazinyl)ethyl)pyridin-1-ium chloride (HL1Cl) and 2, Bi(III) complex ([BiHL2Cl4] × 1/2CH3OH), with (E)-N,N,N-trimethyl-2-oxo-2-(2-(1-(thiazol-2-yl)ethylidene)hydrazinyl)ethan-1-aminium chloride (HL2Cl), have been reported. Zn(II) complex possesses a distorted trigonal bipyramidal geometry while surroundings around Bi(III) ion are extended pentagonal bipyramidal. Antimicrobial activity, brine shrimp assay and DPPH radical scavenging activity of both complexes, including previously synthesized complexes with HL2Cl ligand (Zn(II) and Ni(II)) and complexes with (E)-N,N,N-trimethyl-2-oxo-2-(2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)ethan-1-aminium chloride (HL3Cl) (Zn(II), Cu(II), Cd(II), Co(II), Fe(III), Ni(II)), were evaluated. For the most active complexes, cytotoxic activity against five malignant cancer cell lines (HeLa, A375, MCF7, PC-3 and A549) and normal cell line HaCaT, as well as generation of reactive oxygen species (ROS), was tested.
PB  - Springer
T2  - JBIC Journal of Biological Inorganic Chemistry
T1  - Supplementary data for the article: Stevanović, N.; Mazzeo, P. P.; Bacchi, A.; Matić, I. Z.; Đorđić Crnogorac, M.; Stanojković, T.; Vujčić, M.; Novaković, I.; Radanović, D.; Šumar-Ristović, M.; Sladić, D.; Čobeljić, B.; Anđelković, K. Synthesis, Characterization, Antimicrobial and Cytotoxic Activity and DNA-Binding Properties of d-Metal Complexes with Hydrazones of Girard’s T and P Reagents. J Biol Inorg Chem 2021. https://doi.org/10.1007/s00775-021-01893-5.
ER  - 
@misc{
author = "Stevanović, Nevena and Mazzeo, Paolo Pio and Bacchi, Alessia and Matić, Ivana Z. and Đorđić Crnogorac, Marija and Stanojković, Tatjana and Vujčić, Miroslava and Novaković, Irena T. and Radanović, Dušanka and Šumar-Ristović, Maja and Sladić, Dušan and Čobeljić, Božidar and Anđelković, Katarina K.",
year = "2021",
abstract = "In this work synthesis, characterization and crystal structures of 1, Zn(II) complex ([ZnL1(NCS)2]), with (E)-1-(2-oxo-2-(2-(quinolin-2-ylmethylene)hydrazinyl)ethyl)pyridin-1-ium chloride (HL1Cl) and 2, Bi(III) complex ([BiHL2Cl4] × 1/2CH3OH), with (E)-N,N,N-trimethyl-2-oxo-2-(2-(1-(thiazol-2-yl)ethylidene)hydrazinyl)ethan-1-aminium chloride (HL2Cl), have been reported. Zn(II) complex possesses a distorted trigonal bipyramidal geometry while surroundings around Bi(III) ion are extended pentagonal bipyramidal. Antimicrobial activity, brine shrimp assay and DPPH radical scavenging activity of both complexes, including previously synthesized complexes with HL2Cl ligand (Zn(II) and Ni(II)) and complexes with (E)-N,N,N-trimethyl-2-oxo-2-(2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)ethan-1-aminium chloride (HL3Cl) (Zn(II), Cu(II), Cd(II), Co(II), Fe(III), Ni(II)), were evaluated. For the most active complexes, cytotoxic activity against five malignant cancer cell lines (HeLa, A375, MCF7, PC-3 and A549) and normal cell line HaCaT, as well as generation of reactive oxygen species (ROS), was tested.",
publisher = "Springer",
journal = "JBIC Journal of Biological Inorganic Chemistry",
title = "Supplementary data for the article: Stevanović, N.; Mazzeo, P. P.; Bacchi, A.; Matić, I. Z.; Đorđić Crnogorac, M.; Stanojković, T.; Vujčić, M.; Novaković, I.; Radanović, D.; Šumar-Ristović, M.; Sladić, D.; Čobeljić, B.; Anđelković, K. Synthesis, Characterization, Antimicrobial and Cytotoxic Activity and DNA-Binding Properties of d-Metal Complexes with Hydrazones of Girard’s T and P Reagents. J Biol Inorg Chem 2021. https://doi.org/10.1007/s00775-021-01893-5."
}
Stevanović, N., Mazzeo, P. P., Bacchi, A., Matić, I. Z., Đorđić Crnogorac, M., Stanojković, T., Vujčić, M., Novaković, I. T., Radanović, D., Šumar-Ristović, M., Sladić, D., Čobeljić, B.,& Anđelković, K. K.. (2021). Supplementary data for the article: Stevanović, N.; Mazzeo, P. P.; Bacchi, A.; Matić, I. Z.; Đorđić Crnogorac, M.; Stanojković, T.; Vujčić, M.; Novaković, I.; Radanović, D.; Šumar-Ristović, M.; Sladić, D.; Čobeljić, B.; Anđelković, K. Synthesis, Characterization, Antimicrobial and Cytotoxic Activity and DNA-Binding Properties of d-Metal Complexes with Hydrazones of Girard’s T and P Reagents. J Biol Inorg Chem 2021. https://doi.org/10.1007/s00775-021-01893-5.. in JBIC Journal of Biological Inorganic Chemistry
Springer..
Stevanović N, Mazzeo PP, Bacchi A, Matić IZ, Đorđić Crnogorac M, Stanojković T, Vujčić M, Novaković IT, Radanović D, Šumar-Ristović M, Sladić D, Čobeljić B, Anđelković KK. Supplementary data for the article: Stevanović, N.; Mazzeo, P. P.; Bacchi, A.; Matić, I. Z.; Đorđić Crnogorac, M.; Stanojković, T.; Vujčić, M.; Novaković, I.; Radanović, D.; Šumar-Ristović, M.; Sladić, D.; Čobeljić, B.; Anđelković, K. Synthesis, Characterization, Antimicrobial and Cytotoxic Activity and DNA-Binding Properties of d-Metal Complexes with Hydrazones of Girard’s T and P Reagents. J Biol Inorg Chem 2021. https://doi.org/10.1007/s00775-021-01893-5.. in JBIC Journal of Biological Inorganic Chemistry. 2021;..
Stevanović, Nevena, Mazzeo, Paolo Pio, Bacchi, Alessia, Matić, Ivana Z., Đorđić Crnogorac, Marija, Stanojković, Tatjana, Vujčić, Miroslava, Novaković, Irena T., Radanović, Dušanka, Šumar-Ristović, Maja, Sladić, Dušan, Čobeljić, Božidar, Anđelković, Katarina K., "Supplementary data for the article: Stevanović, N.; Mazzeo, P. P.; Bacchi, A.; Matić, I. Z.; Đorđić Crnogorac, M.; Stanojković, T.; Vujčić, M.; Novaković, I.; Radanović, D.; Šumar-Ristović, M.; Sladić, D.; Čobeljić, B.; Anđelković, K. Synthesis, Characterization, Antimicrobial and Cytotoxic Activity and DNA-Binding Properties of d-Metal Complexes with Hydrazones of Girard’s T and P Reagents. J Biol Inorg Chem 2021. https://doi.org/10.1007/s00775-021-01893-5." in JBIC Journal of Biological Inorganic Chemistry (2021).

Antioxidant Capacity and Quality of Human Milk and Infant Formula Determined by Direct Current Polarography

Lugonja, Nikoleta; Gorjanović, Stanislava; Pastor, Ferenc; Marinković, Vesna S.; Miličić, Biljana; Vrvić, Miroslav M.; Spasić, Snežana

(Springer Link, 2021)

TY  - JOUR
AU  - Lugonja, Nikoleta
AU  - Gorjanović, Stanislava
AU  - Pastor, Ferenc
AU  - Marinković, Vesna S.
AU  - Miličić, Biljana
AU  - Vrvić, Miroslav M.
AU  - Spasić, Snežana
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4517
AB  - Antioxidants present in infant food contribute to its nutritive value and provide protection from oxidative damage. Here, a direct current polarographic method, based on a decrease of anodic current from the hydroxoperhydroxo-mercury(II) complex (HPMC) formed at a mercury dropping electrode at its potential of dissolution, was used to determine the total antioxidant capacity (TAC) of infant formulas, human milk collected from mothers of full-term and preterm infants, human milk supplemented with fortifier, and cow milk. TAC of milk samples and infant formula correlated with protein content measured by the Bradford method (Pearson correlation coefficient 0.605, p<0.001), while TAC of human milk correlated with content of free thiol groups measured by the Ellman method (0.779, p<0.001). The results obtained showed that, in contrast to the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, HPMC enables specific insight into the quality of infant milk food which reflects the amounts of free thiol groups and protein content. The significant contribution of milk proteins and the most prevalent amino acids, particularly cysteine, arginine, and phenylalanine, to TAC was shown. Thus, the HPMC method might be useful in monitoring the quality of infant formulas and human milk for preterm infants before and after supplementation with fortifier.
PB  - Springer Link
T2  - Food Analytical Methods
T2  - Food Analytical Methods
T1  - Antioxidant Capacity and Quality of Human Milk and Infant Formula Determined by Direct Current Polarography
VL  - 14
SP  - 1987
EP  - 1994
DO  - 10.1007/s12161-021-02030-3
ER  - 
@article{
author = "Lugonja, Nikoleta and Gorjanović, Stanislava and Pastor, Ferenc and Marinković, Vesna S. and Miličić, Biljana and Vrvić, Miroslav M. and Spasić, Snežana",
year = "2021",
abstract = "Antioxidants present in infant food contribute to its nutritive value and provide protection from oxidative damage. Here, a direct current polarographic method, based on a decrease of anodic current from the hydroxoperhydroxo-mercury(II) complex (HPMC) formed at a mercury dropping electrode at its potential of dissolution, was used to determine the total antioxidant capacity (TAC) of infant formulas, human milk collected from mothers of full-term and preterm infants, human milk supplemented with fortifier, and cow milk. TAC of milk samples and infant formula correlated with protein content measured by the Bradford method (Pearson correlation coefficient 0.605, p<0.001), while TAC of human milk correlated with content of free thiol groups measured by the Ellman method (0.779, p<0.001). The results obtained showed that, in contrast to the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, HPMC enables specific insight into the quality of infant milk food which reflects the amounts of free thiol groups and protein content. The significant contribution of milk proteins and the most prevalent amino acids, particularly cysteine, arginine, and phenylalanine, to TAC was shown. Thus, the HPMC method might be useful in monitoring the quality of infant formulas and human milk for preterm infants before and after supplementation with fortifier.",
publisher = "Springer Link",
journal = "Food Analytical Methods, Food Analytical Methods",
title = "Antioxidant Capacity and Quality of Human Milk and Infant Formula Determined by Direct Current Polarography",
volume = "14",
pages = "1987-1994",
doi = "10.1007/s12161-021-02030-3"
}
Lugonja, N., Gorjanović, S., Pastor, F., Marinković, V. S., Miličić, B., Vrvić, M. M.,& Spasić, S.. (2021). Antioxidant Capacity and Quality of Human Milk and Infant Formula Determined by Direct Current Polarography. in Food Analytical Methods
Springer Link., 14, 1987-1994.
https://doi.org/10.1007/s12161-021-02030-3
Lugonja N, Gorjanović S, Pastor F, Marinković VS, Miličić B, Vrvić MM, Spasić S. Antioxidant Capacity and Quality of Human Milk and Infant Formula Determined by Direct Current Polarography. in Food Analytical Methods. 2021;14:1987-1994.
doi:10.1007/s12161-021-02030-3 .
Lugonja, Nikoleta, Gorjanović, Stanislava, Pastor, Ferenc, Marinković, Vesna S., Miličić, Biljana, Vrvić, Miroslav M., Spasić, Snežana, "Antioxidant Capacity and Quality of Human Milk and Infant Formula Determined by Direct Current Polarography" in Food Analytical Methods, 14 (2021):1987-1994,
https://doi.org/10.1007/s12161-021-02030-3 . .

DFT study of the radical scavenging activity of isoxanthohumol, humulones (α-acids), and iso-α-acids from beer

Cvijetić, Ilija; Bigović, Miljan; Ristivojević, Petar; Vitorović-Todorović, Maja D.; Zloh, Mire; Milojković-Opsenica, Dušanka

(Springer, 2021)

TY  - JOUR
AU  - Cvijetić, Ilija
AU  - Bigović, Miljan
AU  - Ristivojević, Petar
AU  - Vitorović-Todorović, Maja D.
AU  - Zloh, Mire
AU  - Milojković-Opsenica, Dušanka
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4534
AB  - Humulones and iso-humulones are potent natural antioxidants found in beer. In this study, density functional theory (DFT) method was applied for elucidating the structure-antioxidant activity relationship and molecular mechanism of antioxidant activity of eight bioactive humulones previously identified in different beer samples: isoxanthohumol, (R)- and (S)-adhumulone, cis- and trans-iso-adhumulone, cis- and trans-iso-n-humulone, and desdimethyl-octahydro-iso-cohumulone. The calculated bond dissociation enthalpies (BDEs) suggest that desdimethyl-octahydro-iso-cohumulone was the most potent compound with BDEs 5.1 and 23.9 kJ/mol lower compared to the values for resveratrol in gas phase and water, respectively. The enolic –OH is the most reactive site for hydrogen atom transfer (HAT). The presence of β-keto group with respect to enolic –OH diminishes the HAT potency via the formation of a strong intramolecular hydrogen bond. Another common antioxidant mechanism, single electron transfer followed by proton transfer (SET-PT), is only feasible for isoxanthohumol. The results of this study indicate a strong correlation between the increased antioxidant activity of beer products and the higher content of reduced iso-α-acids.
PB  - Springer
T2  - Structural Chemistry
T1  - DFT study of the radical scavenging activity of isoxanthohumol, humulones (α-acids), and iso-α-acids from beer
VL  - 32
SP  - 2051
EP  - 2059
DO  - 10.1007/s11224-021-01780-4
ER  - 
@article{
author = "Cvijetić, Ilija and Bigović, Miljan and Ristivojević, Petar and Vitorović-Todorović, Maja D. and Zloh, Mire and Milojković-Opsenica, Dušanka",
year = "2021",
abstract = "Humulones and iso-humulones are potent natural antioxidants found in beer. In this study, density functional theory (DFT) method was applied for elucidating the structure-antioxidant activity relationship and molecular mechanism of antioxidant activity of eight bioactive humulones previously identified in different beer samples: isoxanthohumol, (R)- and (S)-adhumulone, cis- and trans-iso-adhumulone, cis- and trans-iso-n-humulone, and desdimethyl-octahydro-iso-cohumulone. The calculated bond dissociation enthalpies (BDEs) suggest that desdimethyl-octahydro-iso-cohumulone was the most potent compound with BDEs 5.1 and 23.9 kJ/mol lower compared to the values for resveratrol in gas phase and water, respectively. The enolic –OH is the most reactive site for hydrogen atom transfer (HAT). The presence of β-keto group with respect to enolic –OH diminishes the HAT potency via the formation of a strong intramolecular hydrogen bond. Another common antioxidant mechanism, single electron transfer followed by proton transfer (SET-PT), is only feasible for isoxanthohumol. The results of this study indicate a strong correlation between the increased antioxidant activity of beer products and the higher content of reduced iso-α-acids.",
publisher = "Springer",
journal = "Structural Chemistry",
title = "DFT study of the radical scavenging activity of isoxanthohumol, humulones (α-acids), and iso-α-acids from beer",
volume = "32",
pages = "2051-2059",
doi = "10.1007/s11224-021-01780-4"
}
Cvijetić, I., Bigović, M., Ristivojević, P., Vitorović-Todorović, M. D., Zloh, M.,& Milojković-Opsenica, D.. (2021). DFT study of the radical scavenging activity of isoxanthohumol, humulones (α-acids), and iso-α-acids from beer. in Structural Chemistry
Springer., 32, 2051-2059.
https://doi.org/10.1007/s11224-021-01780-4
Cvijetić I, Bigović M, Ristivojević P, Vitorović-Todorović MD, Zloh M, Milojković-Opsenica D. DFT study of the radical scavenging activity of isoxanthohumol, humulones (α-acids), and iso-α-acids from beer. in Structural Chemistry. 2021;32:2051-2059.
doi:10.1007/s11224-021-01780-4 .
Cvijetić, Ilija, Bigović, Miljan, Ristivojević, Petar, Vitorović-Todorović, Maja D., Zloh, Mire, Milojković-Opsenica, Dušanka, "DFT study of the radical scavenging activity of isoxanthohumol, humulones (α-acids), and iso-α-acids from beer" in Structural Chemistry, 32 (2021):2051-2059,
https://doi.org/10.1007/s11224-021-01780-4 . .
2
2
1

New applications of advanced instrumental techniques for the characterization of food allergenic proteins

Benedé, Sara; Lozano-Ojalvo, Daniel; Cristobal, Susana; Costa, Joana; D’Auria, Enza; Ćirković-Veličković, Tanja; Garrido-Arandia, María; Karakaya, Sibel; Mafra, Isabel; Mazzucchelli, Gabriel; Picariello, Gianluca; Romero-Sahagun, Alejandro; Villa, Caterina; Roncada, Paola; Molina, Elena

(Taylor & Francis Group, 2021)

TY  - JOUR
AU  - Benedé, Sara
AU  - Lozano-Ojalvo, Daniel
AU  - Cristobal, Susana
AU  - Costa, Joana
AU  - D’Auria, Enza
AU  - Ćirković-Veličković, Tanja
AU  - Garrido-Arandia, María
AU  - Karakaya, Sibel
AU  - Mafra, Isabel
AU  - Mazzucchelli, Gabriel
AU  - Picariello, Gianluca
AU  - Romero-Sahagun, Alejandro
AU  - Villa, Caterina
AU  - Roncada, Paola
AU  - Molina, Elena
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4548
AB  - Current approaches based on electrophoretic, chromatographic or immunochemical principles have allowed characterizing multiple allergens, mapping their epitopes, studying their mechanisms of action, developing detection and diagnostic methods and therapeutic strategies for the food and pharmaceutical industry. However, some of the common structural features related to the allergenic potential of food proteins remain unknown, or the pathological mechanism of food allergy is not yet fully understood. In addition, it is also necessary to evaluate new allergens from novel protein sources that may pose a new risk for consumers. Technological development has allowed the expansion of advanced technologies for which their whole potential has not been entirely exploited and could provide novel contributions to still unexplored molecular traits underlying both the structure of food allergens and the mechanisms through which they sensitize or elicit adverse responses in human subjects, as well as improving analytical techniques for their detection. This review presents cutting-edge instrumental techniques recently applied when studying structural and functional aspects of proteins, mechanism of action and interaction between biomolecules. We also exemplify their role in the food allergy research and discuss their new possible applications in several areas of the food allergy field.
PB  - Taylor & Francis Group
T2  - Critical Reviews in Food Science and Nutrition
T1  - New applications of advanced instrumental techniques for the characterization of food allergenic proteins
VL  - n/a
DO  - 10.1080/10408398.2021.1931806
ER  - 
@article{
author = "Benedé, Sara and Lozano-Ojalvo, Daniel and Cristobal, Susana and Costa, Joana and D’Auria, Enza and Ćirković-Veličković, Tanja and Garrido-Arandia, María and Karakaya, Sibel and Mafra, Isabel and Mazzucchelli, Gabriel and Picariello, Gianluca and Romero-Sahagun, Alejandro and Villa, Caterina and Roncada, Paola and Molina, Elena",
year = "2021",
abstract = "Current approaches based on electrophoretic, chromatographic or immunochemical principles have allowed characterizing multiple allergens, mapping their epitopes, studying their mechanisms of action, developing detection and diagnostic methods and therapeutic strategies for the food and pharmaceutical industry. However, some of the common structural features related to the allergenic potential of food proteins remain unknown, or the pathological mechanism of food allergy is not yet fully understood. In addition, it is also necessary to evaluate new allergens from novel protein sources that may pose a new risk for consumers. Technological development has allowed the expansion of advanced technologies for which their whole potential has not been entirely exploited and could provide novel contributions to still unexplored molecular traits underlying both the structure of food allergens and the mechanisms through which they sensitize or elicit adverse responses in human subjects, as well as improving analytical techniques for their detection. This review presents cutting-edge instrumental techniques recently applied when studying structural and functional aspects of proteins, mechanism of action and interaction between biomolecules. We also exemplify their role in the food allergy research and discuss their new possible applications in several areas of the food allergy field.",
publisher = "Taylor & Francis Group",
journal = "Critical Reviews in Food Science and Nutrition",
title = "New applications of advanced instrumental techniques for the characterization of food allergenic proteins",
volume = "n/a",
doi = "10.1080/10408398.2021.1931806"
}
Benedé, S., Lozano-Ojalvo, D., Cristobal, S., Costa, J., D’Auria, E., Ćirković-Veličković, T., Garrido-Arandia, M., Karakaya, S., Mafra, I., Mazzucchelli, G., Picariello, G., Romero-Sahagun, A., Villa, C., Roncada, P.,& Molina, E.. (2021). New applications of advanced instrumental techniques for the characterization of food allergenic proteins. in Critical Reviews in Food Science and Nutrition
Taylor & Francis Group., n/a.
https://doi.org/10.1080/10408398.2021.1931806
Benedé S, Lozano-Ojalvo D, Cristobal S, Costa J, D’Auria E, Ćirković-Veličković T, Garrido-Arandia M, Karakaya S, Mafra I, Mazzucchelli G, Picariello G, Romero-Sahagun A, Villa C, Roncada P, Molina E. New applications of advanced instrumental techniques for the characterization of food allergenic proteins. in Critical Reviews in Food Science and Nutrition. 2021;n/a.
doi:10.1080/10408398.2021.1931806 .
Benedé, Sara, Lozano-Ojalvo, Daniel, Cristobal, Susana, Costa, Joana, D’Auria, Enza, Ćirković-Veličković, Tanja, Garrido-Arandia, María, Karakaya, Sibel, Mafra, Isabel, Mazzucchelli, Gabriel, Picariello, Gianluca, Romero-Sahagun, Alejandro, Villa, Caterina, Roncada, Paola, Molina, Elena, "New applications of advanced instrumental techniques for the characterization of food allergenic proteins" in Critical Reviews in Food Science and Nutrition, n/a (2021),
https://doi.org/10.1080/10408398.2021.1931806 . .
1
1

Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles

Radović, Magdalena; Mirković, Marija; Nikolić, Aleksandar S.; Kuraica, Milorad; Iskrenović, Predrag; Milanović, Zorana; Vranješ-Đurić, Sanja; Perić, Marko

(Springer, 2021)

TY  - JOUR
AU  - Radović, Magdalena
AU  - Mirković, Marija
AU  - Nikolić, Aleksandar S.
AU  - Kuraica, Milorad
AU  - Iskrenović, Predrag
AU  - Milanović, Zorana
AU  - Vranješ-Đurić, Sanja
AU  - Perić, Marko
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4569
AB  - Different phosphates and phosphonates have shown excellent coating ability toward magnetic nanoparticles, improving their stability and biocompatibility which enables their biomedical application. The magnetic hyperthermia efficiency of phosphates (IDP and IHP) and phosphonates (MDP and HEDP) coated Fe3O4 magnetic nanoparticles (MNPs) were evaluated in an alternating magnetic field. For a deeper understanding of hyperthermia, the behavior of investigated MNPs in the non-alternating magnetic field was monitored by measuring the transparency of the sample. To investigate their theranostic potential coated Fe3O4-MNPs were radiolabeled with radionuclide 177Lu. Phosphate coated MNPs were radiolabeled in high radiolabeling yield (&gt; 99%) while phosphonate coated MNPs reached maximum radiolabeling yield of 78%. Regardless lower radiolabeling yield both radiolabeled phosphonate MNPs may be further purified reaching radiochemical purity of more than 95%. In vitro stabile radiolabeled nanoparticles in saline and HSA were obtained. The high heating ability of phosphates and phosphonates coated MNPs as sine qua non for efficient in vivo hyperthermia treatment and satisfactory radiolabeling yield justifies their further research in order to develop new theranostic agents. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PB  - Springer
T2  - Journal of Inorganic and Organometallic Polymers and Materials
T1  - Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles
VL  - 31
SP  - 4426
EP  - 4433
DO  - 10.1007/s10904-021-02059-1
ER  - 
@article{
author = "Radović, Magdalena and Mirković, Marija and Nikolić, Aleksandar S. and Kuraica, Milorad and Iskrenović, Predrag and Milanović, Zorana and Vranješ-Đurić, Sanja and Perić, Marko",
year = "2021",
abstract = "Different phosphates and phosphonates have shown excellent coating ability toward magnetic nanoparticles, improving their stability and biocompatibility which enables their biomedical application. The magnetic hyperthermia efficiency of phosphates (IDP and IHP) and phosphonates (MDP and HEDP) coated Fe3O4 magnetic nanoparticles (MNPs) were evaluated in an alternating magnetic field. For a deeper understanding of hyperthermia, the behavior of investigated MNPs in the non-alternating magnetic field was monitored by measuring the transparency of the sample. To investigate their theranostic potential coated Fe3O4-MNPs were radiolabeled with radionuclide 177Lu. Phosphate coated MNPs were radiolabeled in high radiolabeling yield (&gt; 99%) while phosphonate coated MNPs reached maximum radiolabeling yield of 78%. Regardless lower radiolabeling yield both radiolabeled phosphonate MNPs may be further purified reaching radiochemical purity of more than 95%. In vitro stabile radiolabeled nanoparticles in saline and HSA were obtained. The high heating ability of phosphates and phosphonates coated MNPs as sine qua non for efficient in vivo hyperthermia treatment and satisfactory radiolabeling yield justifies their further research in order to develop new theranostic agents. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",
publisher = "Springer",
journal = "Journal of Inorganic and Organometallic Polymers and Materials",
title = "Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles",
volume = "31",
pages = "4426-4433",
doi = "10.1007/s10904-021-02059-1"
}
Radović, M., Mirković, M., Nikolić, A. S., Kuraica, M., Iskrenović, P., Milanović, Z., Vranješ-Đurić, S.,& Perić, M.. (2021). Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles. in Journal of Inorganic and Organometallic Polymers and Materials
Springer., 31, 4426-4433.
https://doi.org/10.1007/s10904-021-02059-1
Radović M, Mirković M, Nikolić AS, Kuraica M, Iskrenović P, Milanović Z, Vranješ-Đurić S, Perić M. Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles. in Journal of Inorganic and Organometallic Polymers and Materials. 2021;31:4426-4433.
doi:10.1007/s10904-021-02059-1 .
Radović, Magdalena, Mirković, Marija, Nikolić, Aleksandar S., Kuraica, Milorad, Iskrenović, Predrag, Milanović, Zorana, Vranješ-Đurić, Sanja, Perić, Marko, "Transmittance Measurements in Non-alternating Magnetic Field as Reliable Method for Determining of Heating Properties of Phosphate and Phosphonate Coated Fe3O4 Magnetic Nanoparticles" in Journal of Inorganic and Organometallic Polymers and Materials, 31 (2021):4426-4433,
https://doi.org/10.1007/s10904-021-02059-1 . .

The programme for professional development of chemistry teachers’ assessment competency

Tomašević, Biljana; Trivić, Dragica; Milanović, Vesna D.; Ralević, Lidija

(Serbian Chemical Society, 2021)

TY  - JOUR
AU  - Tomašević, Biljana
AU  - Trivić, Dragica
AU  - Milanović, Vesna D.
AU  - Ralević, Lidija
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4786
AB  - The aim of this paper is to investigate the effects of the programme for professional development of chemistry teachers on their competencies for conducting formative and summative assessment in chemistry teaching. The programme participants were 30 chemistry teachers from primary and secondary schools. Data were collected using a questionnaire at the beginning and at the end of the programme implementation. The programme included four workshops with the same structure: the introduction, group work and the discussion of the results obtained through group work. The workshops focused on: i) the assessment as a support for chemistry learning; ii) the harmonization of teaching and learning activities, formative and summative assessment, feedback from formative assessment and the criteria used to evaluate students in summative assessment; iii) the evaluation of the validity of tasks used for formative and summative assessment according to the curricula aims and the educational standards; iv) designing tasks for monitoring students’ progress towards certain educational standards. Teachers’ responses show the impact of the programme for the development of their competencies for assessment, particularly regarding formative and summative assessment and designing various kinds of assessment in accordance with the achievement standards.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - The programme for professional development of chemistry teachers’ assessment competency
VL  - 86
IS  - 10
SP  - 997
EP  - 1010
DO  - 10.2298/JSC210710052T
ER  - 
@article{
author = "Tomašević, Biljana and Trivić, Dragica and Milanović, Vesna D. and Ralević, Lidija",
year = "2021",
abstract = "The aim of this paper is to investigate the effects of the programme for professional development of chemistry teachers on their competencies for conducting formative and summative assessment in chemistry teaching. The programme participants were 30 chemistry teachers from primary and secondary schools. Data were collected using a questionnaire at the beginning and at the end of the programme implementation. The programme included four workshops with the same structure: the introduction, group work and the discussion of the results obtained through group work. The workshops focused on: i) the assessment as a support for chemistry learning; ii) the harmonization of teaching and learning activities, formative and summative assessment, feedback from formative assessment and the criteria used to evaluate students in summative assessment; iii) the evaluation of the validity of tasks used for formative and summative assessment according to the curricula aims and the educational standards; iv) designing tasks for monitoring students’ progress towards certain educational standards. Teachers’ responses show the impact of the programme for the development of their competencies for assessment, particularly regarding formative and summative assessment and designing various kinds of assessment in accordance with the achievement standards.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "The programme for professional development of chemistry teachers’ assessment competency",
volume = "86",
number = "10",
pages = "997-1010",
doi = "10.2298/JSC210710052T"
}
Tomašević, B., Trivić, D., Milanović, V. D.,& Ralević, L.. (2021). The programme for professional development of chemistry teachers’ assessment competency. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 86(10), 997-1010.
https://doi.org/10.2298/JSC210710052T
Tomašević B, Trivić D, Milanović VD, Ralević L. The programme for professional development of chemistry teachers’ assessment competency. in Journal of the Serbian Chemical Society. 2021;86(10):997-1010.
doi:10.2298/JSC210710052T .
Tomašević, Biljana, Trivić, Dragica, Milanović, Vesna D., Ralević, Lidija, "The programme for professional development of chemistry teachers’ assessment competency" in Journal of the Serbian Chemical Society, 86, no. 10 (2021):997-1010,
https://doi.org/10.2298/JSC210710052T . .

Molecular Mechanisms of Possible Action of Phenolic Compounds in COVID-19 Protection and Prevention

Gligorijevic, Nikola; Radomirovic, Mirjana; Nedic, Olgica; Stojadinovic, Marija; Khulal, Urmila; Stanic-Vucinic, Dragana; Cirkovic Velickovic, Tanja

(MDPI, 2021)

TY  - JOUR
AU  - Gligorijevic, Nikola
AU  - Radomirovic, Mirjana
AU  - Nedic, Olgica
AU  - Stojadinovic, Marija
AU  - Khulal, Urmila
AU  - Stanic-Vucinic, Dragana
AU  - Cirkovic Velickovic, Tanja
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4784
AB  - The worldwide outbreak of COVID-19 was caused by a pathogenic virus called Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Therapies against SARS-CoV-2 target the virus or human cells or the immune system. However, therapies based on specific antibodies, such as vaccines and monoclonal antibodies, may become inefficient enough when the virus changes its antigenicity due to mutations. Polyphenols are the major class of bioactive compounds in nature, exerting diverse health effects based on their direct antioxidant activity and their effects in the modulation of intracellular signaling. There are currently numerous clinical trials investigating the effects of polyphenols in prophylaxis and the treatment of COVID-19, from symptomatic, via moderate and severe COVID-19 treatment, to anti-fibrotic treatment in discharged COVID-19 patients. Antiviral activities of polyphenols and their impact on immune system modulation could serve as a solid basis for developing polyphenol-based natural approaches for preventing and treating COVID-19.
PB  - MDPI
T2  - International Journal of Molecular Sciences
T1  - Molecular Mechanisms of Possible Action of Phenolic Compounds in COVID-19 Protection and Prevention
VL  - 22
IS  - 22
SP  - 12385
DO  - 10.3390/ijms222212385
ER  - 
@article{
author = "Gligorijevic, Nikola and Radomirovic, Mirjana and Nedic, Olgica and Stojadinovic, Marija and Khulal, Urmila and Stanic-Vucinic, Dragana and Cirkovic Velickovic, Tanja",
year = "2021",
abstract = "The worldwide outbreak of COVID-19 was caused by a pathogenic virus called Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Therapies against SARS-CoV-2 target the virus or human cells or the immune system. However, therapies based on specific antibodies, such as vaccines and monoclonal antibodies, may become inefficient enough when the virus changes its antigenicity due to mutations. Polyphenols are the major class of bioactive compounds in nature, exerting diverse health effects based on their direct antioxidant activity and their effects in the modulation of intracellular signaling. There are currently numerous clinical trials investigating the effects of polyphenols in prophylaxis and the treatment of COVID-19, from symptomatic, via moderate and severe COVID-19 treatment, to anti-fibrotic treatment in discharged COVID-19 patients. Antiviral activities of polyphenols and their impact on immune system modulation could serve as a solid basis for developing polyphenol-based natural approaches for preventing and treating COVID-19.",
publisher = "MDPI",
journal = "International Journal of Molecular Sciences",
title = "Molecular Mechanisms of Possible Action of Phenolic Compounds in COVID-19 Protection and Prevention",
volume = "22",
number = "22",
pages = "12385",
doi = "10.3390/ijms222212385"
}
Gligorijevic, N., Radomirovic, M., Nedic, O., Stojadinovic, M., Khulal, U., Stanic-Vucinic, D.,& Cirkovic Velickovic, T.. (2021). Molecular Mechanisms of Possible Action of Phenolic Compounds in COVID-19 Protection and Prevention. in International Journal of Molecular Sciences
MDPI., 22(22), 12385.
https://doi.org/10.3390/ijms222212385
Gligorijevic N, Radomirovic M, Nedic O, Stojadinovic M, Khulal U, Stanic-Vucinic D, Cirkovic Velickovic T. Molecular Mechanisms of Possible Action of Phenolic Compounds in COVID-19 Protection and Prevention. in International Journal of Molecular Sciences. 2021;22(22):12385.
doi:10.3390/ijms222212385 .
Gligorijevic, Nikola, Radomirovic, Mirjana, Nedic, Olgica, Stojadinovic, Marija, Khulal, Urmila, Stanic-Vucinic, Dragana, Cirkovic Velickovic, Tanja, "Molecular Mechanisms of Possible Action of Phenolic Compounds in COVID-19 Protection and Prevention" in International Journal of Molecular Sciences, 22, no. 22 (2021):12385,
https://doi.org/10.3390/ijms222212385 . .
1

The Thermochemistry of Alkyne Insertion into a Palladacycle Outlines the Solvation Conundrum in DFT

Milovanović, Milan R.; Boucher, Mélanie; Cornaton, Yann; Zarić, Snežana D.; Pfeffer, Michel; Djukic, Jean-Pierre

(Wiley, 2021)

TY  - JOUR
AU  - Milovanović, Milan R.
AU  - Boucher, Mélanie
AU  - Cornaton, Yann
AU  - Zarić, Snežana D.
AU  - Pfeffer, Michel
AU  - Djukic, Jean-Pierre
PY  - 2021
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1002/ejic.202100750
UR  - C:\Users\Ana\Zotero\storage\ZAYTN3C5\Milovanović et al. - 2021 - The Thermochemistry of Alkyne Insertion into a Pal.pdf
UR  - C:\Users\Ana\Zotero\storage\JYEI976E\ejic.html
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4783
AB  - In an effort to determine the thermochemistry of established organometallic transformation, the well documented reaction of alkynes with a palladacycle was investigated by isothermal titration calorimetry (ITC). Although the mechanism of the insertion of unsaturated substrates into the Pd−C bond of cyclopalladated compounds is known, no information is available so far about their thermochemistry. The enthalpies of the reactions of Ph−C≡C−Ph and MeOC(O)−C≡C(O)COMe with the bisacetonitrilo salt of the N,N-benzylamine palladacycle were determined by ITC in chlorobenzene after having optimized the conditions to ensure that only the double and a single insertion of alkynes were occurring respectively. The reaction energy profile established by DFT for the double insertion process involving Ph−C≡C−Ph confirmed earlier conclusions on the rate determining character of the first insertion. Further computations of reaction enthalpies reveal significant discrepancies between ITC and DFT-D/continuum solvation enthalpies, that are suspected to arise from an unexpected explicit noncovalent interaction of PhCl with the components of the reaction.
PB  - Wiley
T2  - European Journal of Inorganic Chemistry
T1  - The Thermochemistry of Alkyne Insertion into a Palladacycle Outlines the Solvation Conundrum in DFT
VL  - 2021
IS  - 45
SP  - 4690
EP  - 4699
DO  - 10.1002/ejic.202100750
ER  - 
@article{
author = "Milovanović, Milan R. and Boucher, Mélanie and Cornaton, Yann and Zarić, Snežana D. and Pfeffer, Michel and Djukic, Jean-Pierre",
year = "2021",
abstract = "In an effort to determine the thermochemistry of established organometallic transformation, the well documented reaction of alkynes with a palladacycle was investigated by isothermal titration calorimetry (ITC). Although the mechanism of the insertion of unsaturated substrates into the Pd−C bond of cyclopalladated compounds is known, no information is available so far about their thermochemistry. The enthalpies of the reactions of Ph−C≡C−Ph and MeOC(O)−C≡C(O)COMe with the bisacetonitrilo salt of the N,N-benzylamine palladacycle were determined by ITC in chlorobenzene after having optimized the conditions to ensure that only the double and a single insertion of alkynes were occurring respectively. The reaction energy profile established by DFT for the double insertion process involving Ph−C≡C−Ph confirmed earlier conclusions on the rate determining character of the first insertion. Further computations of reaction enthalpies reveal significant discrepancies between ITC and DFT-D/continuum solvation enthalpies, that are suspected to arise from an unexpected explicit noncovalent interaction of PhCl with the components of the reaction.",
publisher = "Wiley",
journal = "European Journal of Inorganic Chemistry",
title = "The Thermochemistry of Alkyne Insertion into a Palladacycle Outlines the Solvation Conundrum in DFT",
volume = "2021",
number = "45",
pages = "4690-4699",
doi = "10.1002/ejic.202100750"
}
Milovanović, M. R., Boucher, M., Cornaton, Y., Zarić, S. D., Pfeffer, M.,& Djukic, J.. (2021). The Thermochemistry of Alkyne Insertion into a Palladacycle Outlines the Solvation Conundrum in DFT. in European Journal of Inorganic Chemistry
Wiley., 2021(45), 4690-4699.
https://doi.org/10.1002/ejic.202100750
Milovanović MR, Boucher M, Cornaton Y, Zarić SD, Pfeffer M, Djukic J. The Thermochemistry of Alkyne Insertion into a Palladacycle Outlines the Solvation Conundrum in DFT. in European Journal of Inorganic Chemistry. 2021;2021(45):4690-4699.
doi:10.1002/ejic.202100750 .
Milovanović, Milan R., Boucher, Mélanie, Cornaton, Yann, Zarić, Snežana D., Pfeffer, Michel, Djukic, Jean-Pierre, "The Thermochemistry of Alkyne Insertion into a Palladacycle Outlines the Solvation Conundrum in DFT" in European Journal of Inorganic Chemistry, 2021, no. 45 (2021):4690-4699,
https://doi.org/10.1002/ejic.202100750 . .
1

Triplet state (anti)aromaticity of some monoheterocyclic analogues of benzene, naphthalene and anthracene

Baranac-Stojanović, Marija; Stojanović, Milovan; Aleksić, Jovana

(Royal Society of Chemistry, 2021)

TY  - JOUR
AU  - Baranac-Stojanović, Marija
AU  - Stojanović, Milovan
AU  - Aleksić, Jovana
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4355
AB  - Aromaticity–antiaromaticity switch upon singlet–triplet transition of some biologically and synthetically important monoheterocycles (heteroatom = N, O, Si, P, and S) derived from benzene, naphthalene and anthracene was studied by employing energetic, magnetic and structural aromaticity criteria, at the density functional theory (DFT) level. The relationship between spin density distribution, (anti)aromaticity and singlet–triplet energy gaps, in the studied molecules, was found. In general, spin delocalization results in antiaromaticity, spin density localization to one ring in bi- and tricycles localizes antiaromaticity and spin localization on a heteroatom reduces global and local antiaromaticity. The latter reaches nonaromaticity in the case of silicon atoms which have larger orbitals and show more tendency to accept unpaired electrons. Spin density localization in bi- and tricycles allows benzene subunit(s) to develop local aromaticity, which, when combined with nonaromatic silacycle and weak global antiaromaticity, results in overall triplet state weak aromaticity. The singlet–triplet energy gaps decrease with a decrease in the triplet state antiaromaticity and are the lowest for silicon-containing compounds.
PB  - Royal Society of Chemistry
T2  - New Journal of Chemistry
T1  - Triplet state (anti)aromaticity of some monoheterocyclic analogues of benzene, naphthalene and anthracene
VL  - 45
IS  - 11
SP  - 5060
EP  - 5074
DO  - 10.1039/D1NJ00207D
ER  - 
@article{
author = "Baranac-Stojanović, Marija and Stojanović, Milovan and Aleksić, Jovana",
year = "2021",
abstract = "Aromaticity–antiaromaticity switch upon singlet–triplet transition of some biologically and synthetically important monoheterocycles (heteroatom = N, O, Si, P, and S) derived from benzene, naphthalene and anthracene was studied by employing energetic, magnetic and structural aromaticity criteria, at the density functional theory (DFT) level. The relationship between spin density distribution, (anti)aromaticity and singlet–triplet energy gaps, in the studied molecules, was found. In general, spin delocalization results in antiaromaticity, spin density localization to one ring in bi- and tricycles localizes antiaromaticity and spin localization on a heteroatom reduces global and local antiaromaticity. The latter reaches nonaromaticity in the case of silicon atoms which have larger orbitals and show more tendency to accept unpaired electrons. Spin density localization in bi- and tricycles allows benzene subunit(s) to develop local aromaticity, which, when combined with nonaromatic silacycle and weak global antiaromaticity, results in overall triplet state weak aromaticity. The singlet–triplet energy gaps decrease with a decrease in the triplet state antiaromaticity and are the lowest for silicon-containing compounds.",
publisher = "Royal Society of Chemistry",
journal = "New Journal of Chemistry",
title = "Triplet state (anti)aromaticity of some monoheterocyclic analogues of benzene, naphthalene and anthracene",
volume = "45",
number = "11",
pages = "5060-5074",
doi = "10.1039/D1NJ00207D"
}
Baranac-Stojanović, M., Stojanović, M.,& Aleksić, J.. (2021). Triplet state (anti)aromaticity of some monoheterocyclic analogues of benzene, naphthalene and anthracene. in New Journal of Chemistry
Royal Society of Chemistry., 45(11), 5060-5074.
https://doi.org/10.1039/D1NJ00207D
Baranac-Stojanović M, Stojanović M, Aleksić J. Triplet state (anti)aromaticity of some monoheterocyclic analogues of benzene, naphthalene and anthracene. in New Journal of Chemistry. 2021;45(11):5060-5074.
doi:10.1039/D1NJ00207D .
Baranac-Stojanović, Marija, Stojanović, Milovan, Aleksić, Jovana, "Triplet state (anti)aromaticity of some monoheterocyclic analogues of benzene, naphthalene and anthracene" in New Journal of Chemistry, 45, no. 11 (2021):5060-5074,
https://doi.org/10.1039/D1NJ00207D . .

Supplementary data for the article: Baranac-Stojanović, M.; Stojanović, M.; Aleksić, J. Triplet State (Anti)Aromaticity of Some Monoheterocyclic Analogues of Benzene, Naphthalene and Anthracene. New J. Chem. 2021, 45 (11), 5060–5074. https://doi.org/10.1039/D1NJ00207D.

Baranac-Stojanović, Marija; Stojanović, Milovan; Aleksić, Jovana

(Royal Society of Chemistry, 2021)

TY  - DATA
AU  - Baranac-Stojanović, Marija
AU  - Stojanović, Milovan
AU  - Aleksić, Jovana
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4356
PB  - Royal Society of Chemistry
T2  - New Journal of Chemistry
T1  - Supplementary data for the article: Baranac-Stojanović, M.; Stojanović, M.; Aleksić, J. Triplet State (Anti)Aromaticity of Some Monoheterocyclic Analogues of Benzene, Naphthalene and Anthracene. New J. Chem. 2021, 45 (11), 5060–5074. https://doi.org/10.1039/D1NJ00207D.
ER  - 
@misc{
author = "Baranac-Stojanović, Marija and Stojanović, Milovan and Aleksić, Jovana",
year = "2021",
publisher = "Royal Society of Chemistry",
journal = "New Journal of Chemistry",
title = "Supplementary data for the article: Baranac-Stojanović, M.; Stojanović, M.; Aleksić, J. Triplet State (Anti)Aromaticity of Some Monoheterocyclic Analogues of Benzene, Naphthalene and Anthracene. New J. Chem. 2021, 45 (11), 5060–5074. https://doi.org/10.1039/D1NJ00207D."
}
Baranac-Stojanović, M., Stojanović, M.,& Aleksić, J.. (2021). Supplementary data for the article: Baranac-Stojanović, M.; Stojanović, M.; Aleksić, J. Triplet State (Anti)Aromaticity of Some Monoheterocyclic Analogues of Benzene, Naphthalene and Anthracene. New J. Chem. 2021, 45 (11), 5060–5074. https://doi.org/10.1039/D1NJ00207D.. in New Journal of Chemistry
Royal Society of Chemistry..
Baranac-Stojanović M, Stojanović M, Aleksić J. Supplementary data for the article: Baranac-Stojanović, M.; Stojanović, M.; Aleksić, J. Triplet State (Anti)Aromaticity of Some Monoheterocyclic Analogues of Benzene, Naphthalene and Anthracene. New J. Chem. 2021, 45 (11), 5060–5074. https://doi.org/10.1039/D1NJ00207D.. in New Journal of Chemistry. 2021;..
Baranac-Stojanović, Marija, Stojanović, Milovan, Aleksić, Jovana, "Supplementary data for the article: Baranac-Stojanović, M.; Stojanović, M.; Aleksić, J. Triplet State (Anti)Aromaticity of Some Monoheterocyclic Analogues of Benzene, Naphthalene and Anthracene. New J. Chem. 2021, 45 (11), 5060–5074. https://doi.org/10.1039/D1NJ00207D." in New Journal of Chemistry (2021).

Supplementary data for the article: Milenković, I.; Radotić, K.; Trifković, J.; Vujisić, L.; Beškoski, V. P. Screening of Semi-Volatile Compounds in Plants Treated with Coated Cerium Oxide Nanoparticles by Comprehensive Two-Dimensional Gas Chromatography. Journal of Separation Science 2021, 44 (11), 2260–2268. https://doi.org/10.1002/jssc.202100145.

Milenković, Ivana; Radotić, Ksenija; Trifković, Jelena; Vujisić, Ljubodrag; Beškoski, Vladimir

(Wiley-VCH, 2021)

TY  - DATA
AU  - Milenković, Ivana
AU  - Radotić, Ksenija
AU  - Trifković, Jelena
AU  - Vujisić, Ljubodrag
AU  - Beškoski, Vladimir
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4520
PB  - Wiley-VCH
T2  - Journal of Separation Science
T1  - Supplementary data for the article: Milenković, I.; Radotić, K.; Trifković, J.; Vujisić, L.; Beškoski, V. P. Screening of Semi-Volatile Compounds in Plants Treated with Coated Cerium Oxide Nanoparticles by Comprehensive Two-Dimensional Gas Chromatography. Journal of Separation Science 2021, 44 (11), 2260–2268. https://doi.org/10.1002/jssc.202100145.
ER  - 
@misc{
author = "Milenković, Ivana and Radotić, Ksenija and Trifković, Jelena and Vujisić, Ljubodrag and Beškoski, Vladimir",
year = "2021",
publisher = "Wiley-VCH",
journal = "Journal of Separation Science",
title = "Supplementary data for the article: Milenković, I.; Radotić, K.; Trifković, J.; Vujisić, L.; Beškoski, V. P. Screening of Semi-Volatile Compounds in Plants Treated with Coated Cerium Oxide Nanoparticles by Comprehensive Two-Dimensional Gas Chromatography. Journal of Separation Science 2021, 44 (11), 2260–2268. https://doi.org/10.1002/jssc.202100145."
}
Milenković, I., Radotić, K., Trifković, J., Vujisić, L.,& Beškoski, V.. (2021). Supplementary data for the article: Milenković, I.; Radotić, K.; Trifković, J.; Vujisić, L.; Beškoski, V. P. Screening of Semi-Volatile Compounds in Plants Treated with Coated Cerium Oxide Nanoparticles by Comprehensive Two-Dimensional Gas Chromatography. Journal of Separation Science 2021, 44 (11), 2260–2268. https://doi.org/10.1002/jssc.202100145.. in Journal of Separation Science
Wiley-VCH..
Milenković I, Radotić K, Trifković J, Vujisić L, Beškoski V. Supplementary data for the article: Milenković, I.; Radotić, K.; Trifković, J.; Vujisić, L.; Beškoski, V. P. Screening of Semi-Volatile Compounds in Plants Treated with Coated Cerium Oxide Nanoparticles by Comprehensive Two-Dimensional Gas Chromatography. Journal of Separation Science 2021, 44 (11), 2260–2268. https://doi.org/10.1002/jssc.202100145.. in Journal of Separation Science. 2021;..
Milenković, Ivana, Radotić, Ksenija, Trifković, Jelena, Vujisić, Ljubodrag, Beškoski, Vladimir, "Supplementary data for the article: Milenković, I.; Radotić, K.; Trifković, J.; Vujisić, L.; Beškoski, V. P. Screening of Semi-Volatile Compounds in Plants Treated with Coated Cerium Oxide Nanoparticles by Comprehensive Two-Dimensional Gas Chromatography. Journal of Separation Science 2021, 44 (11), 2260–2268. https://doi.org/10.1002/jssc.202100145." in Journal of Separation Science (2021).