TY  - JOUR
AU  - Djinovic, Vesna M.
AU  - Glodjovic, Verica V.
AU  - Vasic, Gordana P.
AU  - Trajković, Vladimir S.
AU  - Klisurić, Olivera
AU  - Stanković, Slobodanka
AU  - Sabo, Tibor
AU  - Trifunović, Srećko R.
PY  - 2010
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1084
AB  - The syntheses of two novel platinum(IV) complexes of formula [PtX2(S,S-eddp)center dot nH(2)O (S,S-eddp = ethylenediamine-N,N'-di-S,S-2-propanoate ion, X = chlorido (1) or bromido (2), n = 4, 0) are reported. The complexes have been obtained by direct reaction of corresponding potassium hexahalogenidoplatinate(IV) with neutralized ethylenediamine-N,N'-di-S,S-2-propanoic acid (H-2-S,S-eddp). The complexes were characterized by elemental analysis, infrared, H-1 and C-13 NMR spectroscopy. The spectroscopically predicted geometrical configurations of the obtained complexes were confirmed by X-ray analyses of the crystal structures of the s-cis-[Pt(S,S-eddp)Cl-2]center dot 4H(2)O and uns-cis-[Pt(S,S-eddp)Br-2]. These complexes displayed significantly lower in vitro cytotoxicity in comparison to cisplatin. (c) 2010 Elsevier Ltd. All rights reserved.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Polyhedron
T1  - Stereospecific ligands and their complexes. IV: Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with ethylenediamine-N,N '-di-S,S-2-propanoate and halogenido ligands: Crystal structure of s-cis-[Pt(S,S-eddp)Cl-2]center dot 4H(
VL  - 29
IS  - 8
SP  - 1933
EP  - 1938
DO  - 10.1016/j.poly.2010.03.004
ER  - 

@article{
author = "Djinovic, Vesna M. and Glodjovic, Verica V. and Vasic, Gordana P. and Trajković, Vladimir S. and Klisurić, Olivera and Stanković, Slobodanka and Sabo, Tibor and Trifunović, Srećko R.",
year = "2010",
abstract = "The syntheses of two novel platinum(IV) complexes of formula [PtX2(S,S-eddp)center dot nH(2)O (S,S-eddp = ethylenediamine-N,N'-di-S,S-2-propanoate ion, X = chlorido (1) or bromido (2), n = 4, 0) are reported. The complexes have been obtained by direct reaction of corresponding potassium hexahalogenidoplatinate(IV) with neutralized ethylenediamine-N,N'-di-S,S-2-propanoic acid (H-2-S,S-eddp). The complexes were characterized by elemental analysis, infrared, H-1 and C-13 NMR spectroscopy. The spectroscopically predicted geometrical configurations of the obtained complexes were confirmed by X-ray analyses of the crystal structures of the s-cis-[Pt(S,S-eddp)Cl-2]center dot 4H(2)O and uns-cis-[Pt(S,S-eddp)Br-2]. These complexes displayed significantly lower in vitro cytotoxicity in comparison to cisplatin. (c) 2010 Elsevier Ltd. All rights reserved.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Polyhedron",
title = "Stereospecific ligands and their complexes. IV: Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with ethylenediamine-N,N '-di-S,S-2-propanoate and halogenido ligands: Crystal structure of s-cis-[Pt(S,S-eddp)Cl-2]center dot 4H(",
volume = "29",
number = "8",
pages = "1933-1938",
doi = "10.1016/j.poly.2010.03.004"
}

Djinovic, V. M., Glodjovic, V. V., Vasic, G. P., Trajković, V. S., Klisurić, O., Stanković, S., Sabo, T.,& Trifunović, S. R.. (2010). Stereospecific ligands and their complexes. IV: Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with ethylenediamine-N,N '-di-S,S-2-propanoate and halogenido ligands: Crystal structure of s-cis-[Pt(S,S-eddp)Cl-2]center dot 4H(. in Polyhedron
Pergamon-Elsevier Science Ltd, Oxford., 29(8), 1933-1938.
https://doi.org/10.1016/j.poly.2010.03.004

Djinovic VM, Glodjovic VV, Vasic GP, Trajković VS, Klisurić O, Stanković S, Sabo T, Trifunović SR. Stereospecific ligands and their complexes. IV: Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with ethylenediamine-N,N '-di-S,S-2-propanoate and halogenido ligands: Crystal structure of s-cis-[Pt(S,S-eddp)Cl-2]center dot 4H(. in Polyhedron. 2010;29(8):1933-1938.
doi:10.1016/j.poly.2010.03.004 .

Djinovic, Vesna M., Glodjovic, Verica V., Vasic, Gordana P., Trajković, Vladimir S., Klisurić, Olivera, Stanković, Slobodanka, Sabo, Tibor, Trifunović, Srećko R., "Stereospecific ligands and their complexes. IV: Synthesis, characterization and cytotoxicity of novel platinum(IV) complexes with ethylenediamine-N,N '-di-S,S-2-propanoate and halogenido ligands: Crystal structure of s-cis-[Pt(S,S-eddp)Cl-2]center dot 4H(" in Polyhedron, 29, no. 8 (2010):1933-1938,
https://doi.org/10.1016/j.poly.2010.03.004 . .

TY  - JOUR
AU  - Gasi, Katarina M. Penov
AU  - Brenesel, Maja Dj. Djurendic
AU  - Djurendic, Evgenija A.
AU  - Sakac, Marija N.
AU  - Canadi, Janos J.
AU  - Daljev, Jovana J.
AU  - Armbruster, Thomas
AU  - Andrić, Silvana A.
AU  - Sladić, Dušan
AU  - Božić, Tatjana T.
AU  - Novaković, Irena T.
AU  - Juranić, Zorica D.
PY  - 2007
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/765
AB  - Starting from dehydroepiandrosterone (1) 17-picolyl (2), 17-picolinylidene (7), 17-picolinylidene-16-one (10 and 11), and 17-picolyl-16-one (15) derivatives of androst-5-ene were synthesized in one, two, four and five steps respectively. By the Oppenauer oxidation or dehydration of 2, 7, 10, and 11 with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ), the corresponding A and B ring modified derivatives 3, 5, 6, 8, 9, and 12-14 were obtained. The structure of 2 was unambiguously proved by the appropriate X-ray structural analysis. Compounds 3, 5,9,12-14 showed inhibitory activity against the enzyme aromatase. Antibacterial activity toxicity to brine shrimp Artemia salina, antitumor activity against three tumor cell lines (human cervix carcinoma HeLa cells, human melanoma FemX cells, and human myelogenous leukemia K562 cells) and toxicity against peripheral blood mononuclear cells were evaluated. Three tested compounds, namely 11, 13, and 15, showed strong activity against all three cell lines, the IC50 values being in the range of 4-10 mu M. (c) 2006 Elsevier Inc. All rights reserved.
PB  - Elsevier Science Inc, New York
T2  - Steroids
T1  - Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives
VL  - 72
IS  - 1
SP  - 31
EP  - 40
DO  - 10.1016/j.steroids.2006.10.002
ER  - 

@article{
author = "Gasi, Katarina M. Penov and Brenesel, Maja Dj. Djurendic and Djurendic, Evgenija A. and Sakac, Marija N. and Canadi, Janos J. and Daljev, Jovana J. and Armbruster, Thomas and Andrić, Silvana A. and Sladić, Dušan and Božić, Tatjana T. and Novaković, Irena T. and Juranić, Zorica D.",
year = "2007",
abstract = "Starting from dehydroepiandrosterone (1) 17-picolyl (2), 17-picolinylidene (7), 17-picolinylidene-16-one (10 and 11), and 17-picolyl-16-one (15) derivatives of androst-5-ene were synthesized in one, two, four and five steps respectively. By the Oppenauer oxidation or dehydration of 2, 7, 10, and 11 with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ), the corresponding A and B ring modified derivatives 3, 5, 6, 8, 9, and 12-14 were obtained. The structure of 2 was unambiguously proved by the appropriate X-ray structural analysis. Compounds 3, 5,9,12-14 showed inhibitory activity against the enzyme aromatase. Antibacterial activity toxicity to brine shrimp Artemia salina, antitumor activity against three tumor cell lines (human cervix carcinoma HeLa cells, human melanoma FemX cells, and human myelogenous leukemia K562 cells) and toxicity against peripheral blood mononuclear cells were evaluated. Three tested compounds, namely 11, 13, and 15, showed strong activity against all three cell lines, the IC50 values being in the range of 4-10 mu M. (c) 2006 Elsevier Inc. All rights reserved.",
publisher = "Elsevier Science Inc, New York",
journal = "Steroids",
title = "Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives",
volume = "72",
number = "1",
pages = "31-40",
doi = "10.1016/j.steroids.2006.10.002"
}

Gasi, K. M. P., Brenesel, M. Dj. D., Djurendic, E. A., Sakac, M. N., Canadi, J. J., Daljev, J. J., Armbruster, T., Andrić, S. A., Sladić, D., Božić, T. T., Novaković, I. T.,& Juranić, Z. D.. (2007). Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives. in Steroids
Elsevier Science Inc, New York., 72(1), 31-40.
https://doi.org/10.1016/j.steroids.2006.10.002

Gasi KMP, Brenesel MDD, Djurendic EA, Sakac MN, Canadi JJ, Daljev JJ, Armbruster T, Andrić SA, Sladić D, Božić TT, Novaković IT, Juranić ZD. Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives. in Steroids. 2007;72(1):31-40.
doi:10.1016/j.steroids.2006.10.002 .

Gasi, Katarina M. Penov, Brenesel, Maja Dj. Djurendic, Djurendic, Evgenija A., Sakac, Marija N., Canadi, Janos J., Daljev, Jovana J., Armbruster, Thomas, Andrić, Silvana A., Sladić, Dušan, Božić, Tatjana T., Novaković, Irena T., Juranić, Zorica D., "Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives" in Steroids, 72, no. 1 (2007):31-40,
https://doi.org/10.1016/j.steroids.2006.10.002 . .