Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200026 (University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM)

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Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200026 (University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM) (en)
Ministarstvo prosvete, nauke i tehnološkog razvoja Republike Srbije, Ugovor br. 451-03-68/2020-14/200026 (Univerzitet u Beogradu, Institut za hemiju, tehnologiju i metalurgiju - IHTM) (sr_RS)
Министарство просвете, науке и технолошког развоја Републике Србије, Уговор бр. 451-03-68/2020-14/200026 (Универзитет у Београду, Институт за хемију, технологију и металургију - ИХТМ) (sr)
Authors

Publications

Novel polyurethane network/organoclay nanocomposites: Microstructure and physicochemical properties

Pergal, Marija V.; Gojgić-Cvijović, Gordana; Steinhart, Miloš; Manojlović, Dragan D.; Ostojić, Sanja B.; Pezo, Lato; Špírková, Milena

(Elsevier, 2022)

TY  - JOUR
AU  - Pergal, Marija V.
AU  - Gojgić-Cvijović, Gordana
AU  - Steinhart, Miloš
AU  - Manojlović, Dragan D.
AU  - Ostojić, Sanja B.
AU  - Pezo, Lato
AU  - Špírková, Milena
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5005
AB  - A series of novel polyurethane network/organoclay nanocomposites (PUN-NCs) with different soft segment contents (30–60 wt%) was prepared by in situ polymerization in solution and characterized. PU network (PUN) was made from poly(dimethylsiloxane)-based macrodiol as the soft segment and 4,4′-methylenediphenyldiisocyanate and hyperbranched polyester of the third pseudo generation as the hard segment. Nanocomposites were obtained by dispersion of organically modified montmorillonite (Cloisite 30B) nanofiller (0.5 wt%). The influence of the soft segment content on the functional properties of PUN-NCs was studied by Fourier transform infrared (FTIR), small-angle and near wide-angle X-ray scattering (SWAXS), thermogravimetric analysis (TGA), dynamic mechanical thermal analyses (DMTA), differential scanning calorimetry (DSC), nanoindentation, atomic force microscopy (AFM), scanning electron microscopy (SEM), and swelling behavior, water absorption and contact angle measurements. The biodegradation process was evaluated using mixed cultures of microorganisms that originated from soil. Mechanically strong PUN-NC materials in the form of films were obtained, pointing to good dispersion and the existence of exfoliated morphology of Cloisite 30B within the PUN matrix, and the nanocomposites with the abovementioned characteristics were obtained as a function of the soft segment content. The decrease of the soft segment content induced a higher degree of phase separated microstructure, increase of Young's modulus, hardness, plasticity, storage modulus, glass transition temperature, surface free energy and swelling ability in tetrahydrofuran, but at the same time, it is responsible for the decrease of crosslinking density and hydrophobicity of PUN-NCs. By choosing adequate soft segment content, the prepared materials can potentially be designed for coating applications, such as top coating materials in environmental conditions.
PB  - Elsevier
T2  - Progress in Organic Coatings
T1  - Novel polyurethane network/organoclay nanocomposites: Microstructure and physicochemical properties
VL  - 163
IS  - 106664
DO  - 10.1016/j.porgcoat.2021.106664
ER  - 
@article{
author = "Pergal, Marija V. and Gojgić-Cvijović, Gordana and Steinhart, Miloš and Manojlović, Dragan D. and Ostojić, Sanja B. and Pezo, Lato and Špírková, Milena",
year = "2022",
abstract = "A series of novel polyurethane network/organoclay nanocomposites (PUN-NCs) with different soft segment contents (30–60 wt%) was prepared by in situ polymerization in solution and characterized. PU network (PUN) was made from poly(dimethylsiloxane)-based macrodiol as the soft segment and 4,4′-methylenediphenyldiisocyanate and hyperbranched polyester of the third pseudo generation as the hard segment. Nanocomposites were obtained by dispersion of organically modified montmorillonite (Cloisite 30B) nanofiller (0.5 wt%). The influence of the soft segment content on the functional properties of PUN-NCs was studied by Fourier transform infrared (FTIR), small-angle and near wide-angle X-ray scattering (SWAXS), thermogravimetric analysis (TGA), dynamic mechanical thermal analyses (DMTA), differential scanning calorimetry (DSC), nanoindentation, atomic force microscopy (AFM), scanning electron microscopy (SEM), and swelling behavior, water absorption and contact angle measurements. The biodegradation process was evaluated using mixed cultures of microorganisms that originated from soil. Mechanically strong PUN-NC materials in the form of films were obtained, pointing to good dispersion and the existence of exfoliated morphology of Cloisite 30B within the PUN matrix, and the nanocomposites with the abovementioned characteristics were obtained as a function of the soft segment content. The decrease of the soft segment content induced a higher degree of phase separated microstructure, increase of Young's modulus, hardness, plasticity, storage modulus, glass transition temperature, surface free energy and swelling ability in tetrahydrofuran, but at the same time, it is responsible for the decrease of crosslinking density and hydrophobicity of PUN-NCs. By choosing adequate soft segment content, the prepared materials can potentially be designed for coating applications, such as top coating materials in environmental conditions.",
publisher = "Elsevier",
journal = "Progress in Organic Coatings",
title = "Novel polyurethane network/organoclay nanocomposites: Microstructure and physicochemical properties",
volume = "163",
number = "106664",
doi = "10.1016/j.porgcoat.2021.106664"
}
Pergal, M. V., Gojgić-Cvijović, G., Steinhart, M., Manojlović, D. D., Ostojić, S. B., Pezo, L.,& Špírková, M.. (2022). Novel polyurethane network/organoclay nanocomposites: Microstructure and physicochemical properties. in Progress in Organic Coatings
Elsevier., 163(106664).
https://doi.org/10.1016/j.porgcoat.2021.106664
Pergal MV, Gojgić-Cvijović G, Steinhart M, Manojlović DD, Ostojić SB, Pezo L, Špírková M. Novel polyurethane network/organoclay nanocomposites: Microstructure and physicochemical properties. in Progress in Organic Coatings. 2022;163(106664).
doi:10.1016/j.porgcoat.2021.106664 .
Pergal, Marija V., Gojgić-Cvijović, Gordana, Steinhart, Miloš, Manojlović, Dragan D., Ostojić, Sanja B., Pezo, Lato, Špírková, Milena, "Novel polyurethane network/organoclay nanocomposites: Microstructure and physicochemical properties" in Progress in Organic Coatings, 163, no. 106664 (2022),
https://doi.org/10.1016/j.porgcoat.2021.106664 . .
1

Supplementary data for the article: Pergal, M. V.; Gojgić-Cvijović, G.; Steinhart, M.; Manojlović, D. D.; Ostojić, S. B.; Pezo, L.; Špírková, M. Novel Polyurethane Network/Organoclay Nanocomposites: Microstructure and Physicochemical Properties. Progress in Organic Coatings 2022, 163 (106664). https://doi.org/10.1016/j.porgcoat.2021.106664.

Pergal, Marija V.; Gojgić-Cvijović, Gordana; Steinhart, Miloš; Manojlović, Dragan D.; Ostojić, Sanja B.; Pezo, Lato; Špírková, Milena

(Elsevier, 2022)

TY  - DATA
AU  - Pergal, Marija V.
AU  - Gojgić-Cvijović, Gordana
AU  - Steinhart, Miloš
AU  - Manojlović, Dragan D.
AU  - Ostojić, Sanja B.
AU  - Pezo, Lato
AU  - Špírková, Milena
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5006
PB  - Elsevier
T2  - Progress in Organic Coatings
T1  - Supplementary data for the article: Pergal, M. V.; Gojgić-Cvijović, G.; Steinhart, M.; Manojlović, D. D.; Ostojić, S. B.; Pezo, L.; Špírková, M. Novel Polyurethane Network/Organoclay Nanocomposites: Microstructure and Physicochemical Properties. Progress in Organic Coatings 2022, 163 (106664). https://doi.org/10.1016/j.porgcoat.2021.106664.
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5006
ER  - 
@misc{
author = "Pergal, Marija V. and Gojgić-Cvijović, Gordana and Steinhart, Miloš and Manojlović, Dragan D. and Ostojić, Sanja B. and Pezo, Lato and Špírková, Milena",
year = "2022",
publisher = "Elsevier",
journal = "Progress in Organic Coatings",
title = "Supplementary data for the article: Pergal, M. V.; Gojgić-Cvijović, G.; Steinhart, M.; Manojlović, D. D.; Ostojić, S. B.; Pezo, L.; Špírková, M. Novel Polyurethane Network/Organoclay Nanocomposites: Microstructure and Physicochemical Properties. Progress in Organic Coatings 2022, 163 (106664). https://doi.org/10.1016/j.porgcoat.2021.106664.",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5006"
}
Pergal, M. V., Gojgić-Cvijović, G., Steinhart, M., Manojlović, D. D., Ostojić, S. B., Pezo, L.,& Špírková, M.. (2022). Supplementary data for the article: Pergal, M. V.; Gojgić-Cvijović, G.; Steinhart, M.; Manojlović, D. D.; Ostojić, S. B.; Pezo, L.; Špírková, M. Novel Polyurethane Network/Organoclay Nanocomposites: Microstructure and Physicochemical Properties. Progress in Organic Coatings 2022, 163 (106664). https://doi.org/10.1016/j.porgcoat.2021.106664.. in Progress in Organic Coatings
Elsevier..
https://hdl.handle.net/21.15107/rcub_cherry_5006
Pergal MV, Gojgić-Cvijović G, Steinhart M, Manojlović DD, Ostojić SB, Pezo L, Špírková M. Supplementary data for the article: Pergal, M. V.; Gojgić-Cvijović, G.; Steinhart, M.; Manojlović, D. D.; Ostojić, S. B.; Pezo, L.; Špírková, M. Novel Polyurethane Network/Organoclay Nanocomposites: Microstructure and Physicochemical Properties. Progress in Organic Coatings 2022, 163 (106664). https://doi.org/10.1016/j.porgcoat.2021.106664.. in Progress in Organic Coatings. 2022;.
https://hdl.handle.net/21.15107/rcub_cherry_5006 .
Pergal, Marija V., Gojgić-Cvijović, Gordana, Steinhart, Miloš, Manojlović, Dragan D., Ostojić, Sanja B., Pezo, Lato, Špírková, Milena, "Supplementary data for the article: Pergal, M. V.; Gojgić-Cvijović, G.; Steinhart, M.; Manojlović, D. D.; Ostojić, S. B.; Pezo, L.; Špírková, M. Novel Polyurethane Network/Organoclay Nanocomposites: Microstructure and Physicochemical Properties. Progress in Organic Coatings 2022, 163 (106664). https://doi.org/10.1016/j.porgcoat.2021.106664." in Progress in Organic Coatings (2022),
https://hdl.handle.net/21.15107/rcub_cherry_5006 .

Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye

Joksimović, Kristina; Kodranov, Igor; Randjelović, Danijela; Slavković Beškoski, Latinka; Radulović, Jelena; Lješević, Marija; Manojlović, Dragan D.; Beškoski, Vladimir P.

(2022)

TY  - JOUR
AU  - Joksimović, Kristina
AU  - Kodranov, Igor
AU  - Randjelović, Danijela
AU  - Slavković Beškoski, Latinka
AU  - Radulović, Jelena
AU  - Lješević, Marija
AU  - Manojlović, Dragan D.
AU  - Beškoski, Vladimir P.
PY  - 2022
UR  - https://www.sciencedirect.com/science/article/pii/S1567539422000391
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5045
AB  - The problem of wastewater has long been ubiquitous and has great consequences for the environment and its inhabitants. Microbial fuel cells (MFCs) have enormous potential for the treatment of wastewaters polluted with azo dyes. The amount of energy that can be produced from a single-chamber MFC is sufficient to perform decolorization and degradation of such dyes, which are widely used in the textile industry. This study on the azo dye, reactive black 5 (RB5), provides an alternative method through three parallel-connected MFCs to obtain electricity that directly serves for the dye’s electrochemical degradation. We examined degradation followed by decolorization of RB5 using Fe and Pt electrodes, together with H2O2, to achieve the electro-Fenton process. The amount of voltage produced (295 mV), the current density (276 mA m−3) and the power density (50 mW m−3) were sufficient to degrade 25 mg L-1 RB5 dye with 0.5 mM H2O2 in just 2 h. The dye degradation mechanism was investigated using UV–VIS, FT-IR and HPLC-MS/MS. The ecotoxicity of the degradation products was assessed using a bacterial model, Aliivibrio fischeri. These tests showed that there was successful degradation of the dye to products whose toxicity is less than that of RB5.
T2  - Bioelectrochemistry
T1  - Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye
VL  - 145
SP  - 108088
DO  - 10.1016/j.bioelechem.2022.108088
ER  - 
@article{
author = "Joksimović, Kristina and Kodranov, Igor and Randjelović, Danijela and Slavković Beškoski, Latinka and Radulović, Jelena and Lješević, Marija and Manojlović, Dragan D. and Beškoski, Vladimir P.",
year = "2022",
abstract = "The problem of wastewater has long been ubiquitous and has great consequences for the environment and its inhabitants. Microbial fuel cells (MFCs) have enormous potential for the treatment of wastewaters polluted with azo dyes. The amount of energy that can be produced from a single-chamber MFC is sufficient to perform decolorization and degradation of such dyes, which are widely used in the textile industry. This study on the azo dye, reactive black 5 (RB5), provides an alternative method through three parallel-connected MFCs to obtain electricity that directly serves for the dye’s electrochemical degradation. We examined degradation followed by decolorization of RB5 using Fe and Pt electrodes, together with H2O2, to achieve the electro-Fenton process. The amount of voltage produced (295 mV), the current density (276 mA m−3) and the power density (50 mW m−3) were sufficient to degrade 25 mg L-1 RB5 dye with 0.5 mM H2O2 in just 2 h. The dye degradation mechanism was investigated using UV–VIS, FT-IR and HPLC-MS/MS. The ecotoxicity of the degradation products was assessed using a bacterial model, Aliivibrio fischeri. These tests showed that there was successful degradation of the dye to products whose toxicity is less than that of RB5.",
journal = "Bioelectrochemistry",
title = "Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye",
volume = "145",
pages = "108088",
doi = "10.1016/j.bioelechem.2022.108088"
}
Joksimović, K., Kodranov, I., Randjelović, D., Slavković Beškoski, L., Radulović, J., Lješević, M., Manojlović, D. D.,& Beškoski, V. P.. (2022). Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye. in Bioelectrochemistry, 145, 108088.
https://doi.org/10.1016/j.bioelechem.2022.108088
Joksimović K, Kodranov I, Randjelović D, Slavković Beškoski L, Radulović J, Lješević M, Manojlović DD, Beškoski VP. Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye. in Bioelectrochemistry. 2022;145:108088.
doi:10.1016/j.bioelechem.2022.108088 .
Joksimović, Kristina, Kodranov, Igor, Randjelović, Danijela, Slavković Beškoski, Latinka, Radulović, Jelena, Lješević, Marija, Manojlović, Dragan D., Beškoski, Vladimir P., "Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye" in Bioelectrochemistry, 145 (2022):108088,
https://doi.org/10.1016/j.bioelechem.2022.108088 . .
1

Characterization of the organic matter in sediments of the Great War Island (Belgrade, Serbia)

Stojadinović, Sanja; Šajnović, Aleksandra; Kašanin-Grubin, Milica; Gajica, Gordana; Veselinović, Gorica; Štrbac, Snežana; Jovančićević, Branimir

(Springer, 2022)

TY  - JOUR
AU  - Stojadinović, Sanja
AU  - Šajnović, Aleksandra
AU  - Kašanin-Grubin, Milica
AU  - Gajica, Gordana
AU  - Veselinović, Gorica
AU  - Štrbac, Snežana
AU  - Jovančićević, Branimir
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5079
AB  - Abstract
Purpose The Great War Island (GWI) is a landform of exceptional features and a protected area located in the center of
Belgrade at the Sava and Danube River’s confluence. The position of GWI causes a large number of possible hydrocar-
bons inputs that influence the quality of both river waters and sediments. The main objective of this research is to assess
the distribution and source of hydrocarbons in sediments deposited at the GWI depending on the river’s flow regimes and
depositional environment.
Material and methods Sediment samples were collected from 16 sites (11 sites along the GWI’s coast, 4 sites from the
inner of the Island, and 1 specific wetland site). The grain size was determined using a standard wet sieving procedure. The
extractable organic matter (OM) was quantified after Soxhlet extraction, and aliphatic and aromatic fractions were isolated
by column chromatography. n-Alkanes, diterpanes, terpanes, steranes, and 16 PAHs are analyzed by gas chromatography-
mass spectrometry.
Results and discussion Sand fraction predominates in coastal samples, and clay size fraction in the samples from the inner
island environment. The predominance of odd higher n-alkanes indicates the terrestrial origin of OM, while the distribution
of lower n-alkanes indicates a certain proportion of algae, bacteria, and/or high maturity of OM. The presence of oil-type
pollutants is confirmed by thermodynamically stable biomarker isomers and/or the presence of unresolved complex mixture
(UCM). Inner island samples are characterized by the largest amount of Corg (up 6%), indicating high bioproductivity and
good preservation of OM. Samples from wetland environment are distinguished by the domination of pimaranes and phyl-
locladanes among saturated hydrocarbons.
Conclusions This study revealed that sediments of the GWI mainly contain native OM with a certain anthropogenic input.
The native OM predominately comes from higher terrestrial plants (Salix alba, Populus nigra, Fraxinus viridis, Taxodium
distichum Rich.), followed by various types of grasses, macrophytes (Salvinia natans, Nymphaea alba), bacteria, algae, and
phytoplankton. Anthropogenic OM originates from petroleum, but also combustion products arrived by deposition from
the air and runoff.
PB  - Springer
T2  - Journal of Soils and Sediments
T1  - Characterization of the organic matter in sediments of the Great War Island (Belgrade, Serbia)
VL  - 22
SP  - 640
EP  - 655
DO  - 10.1007/s11368-021-03103-w
ER  - 
@article{
author = "Stojadinović, Sanja and Šajnović, Aleksandra and Kašanin-Grubin, Milica and Gajica, Gordana and Veselinović, Gorica and Štrbac, Snežana and Jovančićević, Branimir",
year = "2022",
abstract = "Abstract
Purpose The Great War Island (GWI) is a landform of exceptional features and a protected area located in the center of
Belgrade at the Sava and Danube River’s confluence. The position of GWI causes a large number of possible hydrocar-
bons inputs that influence the quality of both river waters and sediments. The main objective of this research is to assess
the distribution and source of hydrocarbons in sediments deposited at the GWI depending on the river’s flow regimes and
depositional environment.
Material and methods Sediment samples were collected from 16 sites (11 sites along the GWI’s coast, 4 sites from the
inner of the Island, and 1 specific wetland site). The grain size was determined using a standard wet sieving procedure. The
extractable organic matter (OM) was quantified after Soxhlet extraction, and aliphatic and aromatic fractions were isolated
by column chromatography. n-Alkanes, diterpanes, terpanes, steranes, and 16 PAHs are analyzed by gas chromatography-
mass spectrometry.
Results and discussion Sand fraction predominates in coastal samples, and clay size fraction in the samples from the inner
island environment. The predominance of odd higher n-alkanes indicates the terrestrial origin of OM, while the distribution
of lower n-alkanes indicates a certain proportion of algae, bacteria, and/or high maturity of OM. The presence of oil-type
pollutants is confirmed by thermodynamically stable biomarker isomers and/or the presence of unresolved complex mixture
(UCM). Inner island samples are characterized by the largest amount of Corg (up 6%), indicating high bioproductivity and
good preservation of OM. Samples from wetland environment are distinguished by the domination of pimaranes and phyl-
locladanes among saturated hydrocarbons.
Conclusions This study revealed that sediments of the GWI mainly contain native OM with a certain anthropogenic input.
The native OM predominately comes from higher terrestrial plants (Salix alba, Populus nigra, Fraxinus viridis, Taxodium
distichum Rich.), followed by various types of grasses, macrophytes (Salvinia natans, Nymphaea alba), bacteria, algae, and
phytoplankton. Anthropogenic OM originates from petroleum, but also combustion products arrived by deposition from
the air and runoff.",
publisher = "Springer",
journal = "Journal of Soils and Sediments",
title = "Characterization of the organic matter in sediments of the Great War Island (Belgrade, Serbia)",
volume = "22",
pages = "640-655",
doi = "10.1007/s11368-021-03103-w"
}
Stojadinović, S., Šajnović, A., Kašanin-Grubin, M., Gajica, G., Veselinović, G., Štrbac, S.,& Jovančićević, B.. (2022). Characterization of the organic matter in sediments of the Great War Island (Belgrade, Serbia). in Journal of Soils and Sediments
Springer., 22, 640-655.
https://doi.org/10.1007/s11368-021-03103-w
Stojadinović S, Šajnović A, Kašanin-Grubin M, Gajica G, Veselinović G, Štrbac S, Jovančićević B. Characterization of the organic matter in sediments of the Great War Island (Belgrade, Serbia). in Journal of Soils and Sediments. 2022;22:640-655.
doi:10.1007/s11368-021-03103-w .
Stojadinović, Sanja, Šajnović, Aleksandra, Kašanin-Grubin, Milica, Gajica, Gordana, Veselinović, Gorica, Štrbac, Snežana, Jovančićević, Branimir, "Characterization of the organic matter in sediments of the Great War Island (Belgrade, Serbia)" in Journal of Soils and Sediments, 22 (2022):640-655,
https://doi.org/10.1007/s11368-021-03103-w . .

Nortriptyline Hydrochloride Solubility-pH Profiles in a Saline Phosphate Buffer: Drug-Phosphate Complexes and Multiple pHmax Domains with a Gibbs Phase Rule “Soft” Constraints

Marković, Olivera S.; Patel, Nirali G.; Serajuddin, Abu T. M.; Avdeef, Alex; Verbić, Tatjana Ž.

(American Chemical Society, 2022)

TY  - JOUR
AU  - Marković, Olivera S.
AU  - Patel, Nirali G.
AU  - Serajuddin, Abu T. M.
AU  - Avdeef, Alex
AU  - Verbić, Tatjana Ž.
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5039
AB  - The solubility of a model basic drug, nortriptyline
(Nor), was investigated as a function of pH in phosphate and/or a
chloride-containing aqueous suspension using experimental
practices recommended in the previously published “white
paper” (Avdeef et al., 2016). The pH-Ramp Shake-Flask (pHRSF) method, introduced in our earlier work (Marković et al.,
2019), was applied. An improved and more detailed experimental
design of the Nor solubility measurement allowed us to exploit the
full capacity of the pH-RSF method. Complex equilibria in the
aqueous phase (cationic and anionic complex formation between
Nor and the phosphate) and solid-phase transformations (Nor free
base, 1:1 Nor hydrochloride salt, 1:1 and 1:2 Nor phosphate salts)
were characterized by a detailed analysis of the solubility
measurements using the computer program pDISOL-X. The solid phases were characterized by thermogravimetric analysis,
differential scanning calorimetry, powder X-ray diffraction, and elemental analyses. The results of the present investigation illustrate
the influence of competing counterions, such as buffering agents, complexing agents, salt coformers, tonicity adjusters, and so forth,
on the aqueous solubility of drugs and interconversion of salts. Careful attention given to these factors can be helpful in the
formulation of drug products.
PB  - American Chemical Society
T2  - Molecular pharmaceutics
T1  - Nortriptyline Hydrochloride Solubility-pH Profiles in a Saline Phosphate Buffer: Drug-Phosphate Complexes and Multiple pHmax Domains with a Gibbs Phase Rule “Soft” Constraints
VL  - 19
IS  - 2
SP  - 710
EP  - 719
DO  - 10.1021/acs.molpharmaceut.1c00919
ER  - 
@article{
author = "Marković, Olivera S. and Patel, Nirali G. and Serajuddin, Abu T. M. and Avdeef, Alex and Verbić, Tatjana Ž.",
year = "2022",
abstract = "The solubility of a model basic drug, nortriptyline
(Nor), was investigated as a function of pH in phosphate and/or a
chloride-containing aqueous suspension using experimental
practices recommended in the previously published “white
paper” (Avdeef et al., 2016). The pH-Ramp Shake-Flask (pHRSF) method, introduced in our earlier work (Marković et al.,
2019), was applied. An improved and more detailed experimental
design of the Nor solubility measurement allowed us to exploit the
full capacity of the pH-RSF method. Complex equilibria in the
aqueous phase (cationic and anionic complex formation between
Nor and the phosphate) and solid-phase transformations (Nor free
base, 1:1 Nor hydrochloride salt, 1:1 and 1:2 Nor phosphate salts)
were characterized by a detailed analysis of the solubility
measurements using the computer program pDISOL-X. The solid phases were characterized by thermogravimetric analysis,
differential scanning calorimetry, powder X-ray diffraction, and elemental analyses. The results of the present investigation illustrate
the influence of competing counterions, such as buffering agents, complexing agents, salt coformers, tonicity adjusters, and so forth,
on the aqueous solubility of drugs and interconversion of salts. Careful attention given to these factors can be helpful in the
formulation of drug products.",
publisher = "American Chemical Society",
journal = "Molecular pharmaceutics",
title = "Nortriptyline Hydrochloride Solubility-pH Profiles in a Saline Phosphate Buffer: Drug-Phosphate Complexes and Multiple pHmax Domains with a Gibbs Phase Rule “Soft” Constraints",
volume = "19",
number = "2",
pages = "710-719",
doi = "10.1021/acs.molpharmaceut.1c00919"
}
Marković, O. S., Patel, N. G., Serajuddin, A. T. M., Avdeef, A.,& Verbić, T. Ž.. (2022). Nortriptyline Hydrochloride Solubility-pH Profiles in a Saline Phosphate Buffer: Drug-Phosphate Complexes and Multiple pHmax Domains with a Gibbs Phase Rule “Soft” Constraints. in Molecular pharmaceutics
American Chemical Society., 19(2), 710-719.
https://doi.org/10.1021/acs.molpharmaceut.1c00919
Marković OS, Patel NG, Serajuddin ATM, Avdeef A, Verbić TŽ. Nortriptyline Hydrochloride Solubility-pH Profiles in a Saline Phosphate Buffer: Drug-Phosphate Complexes and Multiple pHmax Domains with a Gibbs Phase Rule “Soft” Constraints. in Molecular pharmaceutics. 2022;19(2):710-719.
doi:10.1021/acs.molpharmaceut.1c00919 .
Marković, Olivera S., Patel, Nirali G., Serajuddin, Abu T. M., Avdeef, Alex, Verbić, Tatjana Ž., "Nortriptyline Hydrochloride Solubility-pH Profiles in a Saline Phosphate Buffer: Drug-Phosphate Complexes and Multiple pHmax Domains with a Gibbs Phase Rule “Soft” Constraints" in Molecular pharmaceutics, 19, no. 2 (2022):710-719,
https://doi.org/10.1021/acs.molpharmaceut.1c00919 . .

Characterization of the organic matter in sediments of the Great War Island (Belgrade, Serbia)

Stojadinović, Sanja; Šajnović, Aleksandra; Kašanin-Grubin, Milica; Gajica, Gordana; Veselinović, Gorica; Štrbac, Snežana; Jovančićević, Branimir

(SpringerLink, 2022)

TY  - JOUR
AU  - Stojadinović, Sanja
AU  - Šajnović, Aleksandra
AU  - Kašanin-Grubin, Milica
AU  - Gajica, Gordana
AU  - Veselinović, Gorica
AU  - Štrbac, Snežana
AU  - Jovančićević, Branimir
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5018
AB  - Purpose The Great War Island (GWI) is a landform of exceptional features and a protected area located in the center of
Belgrade at the Sava and Danube River’s confuence. The position of GWI causes a large number of possible hydrocarbons inputs that infuence the quality of both river waters and sediments. The main objective of this research is to assess
the distribution and source of hydrocarbons in sediments deposited at the GWI depending on the river’s fow regimes and
depositional environment.
Material and methods Sediment samples were collected from 16 sites (11 sites along the GWI’s coast, 4 sites from the
inner of the Island, and 1 specifc wetland site). The grain size was determined using a standard wet sieving procedure. The
extractable organic matter (OM) was quantifed after Soxhlet extraction, and aliphatic and aromatic fractions were isolated
by column chromatography. n-Alkanes, diterpanes, terpanes, steranes, and 16 PAHs are analyzed by gas chromatographymass spectrometry.
Results and discussion Sand fraction predominates in coastal samples, and clay size fraction in the samples from the inner
island environment. The predominance of odd higher n-alkanes indicates the terrestrial origin of OM, while the distribution
of lower n-alkanes indicates a certain proportion of algae, bacteria, and/or high maturity of OM. The presence of oil-type
pollutants is confrmed by thermodynamically stable biomarker isomers and/or the presence of unresolved complex mixture
(UCM). Inner island samples are characterized by the largest amount of Corg (up 6%), indicating high bioproductivity and
good preservation of OM. Samples from wetland environment are distinguished by the domination of pimaranes and phyllocladanes among saturated hydrocarbons.
Conclusions This study revealed that sediments of the GWI mainly contain native OM with a certain anthropogenic input.
The native OM predominately comes from higher terrestrial plants (Salix alba, Populus nigra, Fraxinus viridis, Taxodium
distichum Rich.), followed by various types of grasses, macrophytes (Salvinia natans, Nymphaea alba), bacteria, algae, and
phytoplankton. Anthropogenic OM originates from petroleum, but also combustion products arrived by deposition from
the air and runof.
PB  - SpringerLink
T2  - Journal of Soils and Sediments
T1  - Characterization of the organic matter in sediments of the Great War Island (Belgrade, Serbia)
VL  - 22
IS  - 2
SP  - 640
EP  - 655
DO  - 10.1007/s11368-021-03103-w
ER  - 
@article{
author = "Stojadinović, Sanja and Šajnović, Aleksandra and Kašanin-Grubin, Milica and Gajica, Gordana and Veselinović, Gorica and Štrbac, Snežana and Jovančićević, Branimir",
year = "2022",
abstract = "Purpose The Great War Island (GWI) is a landform of exceptional features and a protected area located in the center of
Belgrade at the Sava and Danube River’s confuence. The position of GWI causes a large number of possible hydrocarbons inputs that infuence the quality of both river waters and sediments. The main objective of this research is to assess
the distribution and source of hydrocarbons in sediments deposited at the GWI depending on the river’s fow regimes and
depositional environment.
Material and methods Sediment samples were collected from 16 sites (11 sites along the GWI’s coast, 4 sites from the
inner of the Island, and 1 specifc wetland site). The grain size was determined using a standard wet sieving procedure. The
extractable organic matter (OM) was quantifed after Soxhlet extraction, and aliphatic and aromatic fractions were isolated
by column chromatography. n-Alkanes, diterpanes, terpanes, steranes, and 16 PAHs are analyzed by gas chromatographymass spectrometry.
Results and discussion Sand fraction predominates in coastal samples, and clay size fraction in the samples from the inner
island environment. The predominance of odd higher n-alkanes indicates the terrestrial origin of OM, while the distribution
of lower n-alkanes indicates a certain proportion of algae, bacteria, and/or high maturity of OM. The presence of oil-type
pollutants is confrmed by thermodynamically stable biomarker isomers and/or the presence of unresolved complex mixture
(UCM). Inner island samples are characterized by the largest amount of Corg (up 6%), indicating high bioproductivity and
good preservation of OM. Samples from wetland environment are distinguished by the domination of pimaranes and phyllocladanes among saturated hydrocarbons.
Conclusions This study revealed that sediments of the GWI mainly contain native OM with a certain anthropogenic input.
The native OM predominately comes from higher terrestrial plants (Salix alba, Populus nigra, Fraxinus viridis, Taxodium
distichum Rich.), followed by various types of grasses, macrophytes (Salvinia natans, Nymphaea alba), bacteria, algae, and
phytoplankton. Anthropogenic OM originates from petroleum, but also combustion products arrived by deposition from
the air and runof.",
publisher = "SpringerLink",
journal = "Journal of Soils and Sediments",
title = "Characterization of the organic matter in sediments of the Great War Island (Belgrade, Serbia)",
volume = "22",
number = "2",
pages = "640-655",
doi = "10.1007/s11368-021-03103-w"
}
Stojadinović, S., Šajnović, A., Kašanin-Grubin, M., Gajica, G., Veselinović, G., Štrbac, S.,& Jovančićević, B.. (2022). Characterization of the organic matter in sediments of the Great War Island (Belgrade, Serbia). in Journal of Soils and Sediments
SpringerLink., 22(2), 640-655.
https://doi.org/10.1007/s11368-021-03103-w
Stojadinović S, Šajnović A, Kašanin-Grubin M, Gajica G, Veselinović G, Štrbac S, Jovančićević B. Characterization of the organic matter in sediments of the Great War Island (Belgrade, Serbia). in Journal of Soils and Sediments. 2022;22(2):640-655.
doi:10.1007/s11368-021-03103-w .
Stojadinović, Sanja, Šajnović, Aleksandra, Kašanin-Grubin, Milica, Gajica, Gordana, Veselinović, Gorica, Štrbac, Snežana, Jovančićević, Branimir, "Characterization of the organic matter in sediments of the Great War Island (Belgrade, Serbia)" in Journal of Soils and Sediments, 22, no. 2 (2022):640-655,
https://doi.org/10.1007/s11368-021-03103-w . .

Comparison of non-destructive techniques and conventionally used spectrometric techniques for determination of elements in plant samples (coniferous leaves)

Orlić, Jovana; Aničić-Urošević, Mira; Vergel, Konstantin; Zinicovscaia, Inga; Stojadinović, Sanja; Gržetić, Ivan; Ilijević, Konstantin

(2022)

TY  - JOUR
AU  - Orlić, Jovana
AU  - Aničić-Urošević, Mira
AU  - Vergel, Konstantin
AU  - Zinicovscaia, Inga
AU  - Stojadinović, Sanja
AU  - Gržetić, Ivan
AU  - Ilijević, Konstantin
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5007
AB  - Conventionally used spectrometric techniques of inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma optical emission spectrometry (ICP-MS) usually involve time-consuming sample preparation procedure of a sample dissolution which requires the usage of aggressive and toxic chemicals. The need for suitable and sustainable analytical methods for direct multi-elemental analysis of plant samples has been increased in recent years. Spectrometric techniques for direct sample analysis, instrumental neutron activation analysis (INAA) and X-ray fluorescence (XRF) have been applied in environmental studies and various fields of screening tests. Nevertheless, these techniques are not commonly used for plant sample analysis and their performances need to be evaluated. This research aimed to assess how reliable non-destructive techniques are in the determination of elements in plants compared to conventionally used spectrometric techniques. A total of 49 plant samples of four conifer species (Pinus nigra, Abies alba, Taxus baccata and Larix decidua) were measured using two conventionally applied (ICP-MS, ICP-OES) and two non-destructive techniques (wavelength dispersive XRF (WD-XRF), INAA). The comparison was performed by investigation of relative ratios of concentrations and by correlation analysis. Moreover, precision of the techniques was examined and compared. The quality control included analysis of NIST pine needles certified reference material (1575a) using all examined techniques. Our results suggest that additional analytical and quality control steps are necessary for reaching the highest accuracy of multi-elemental analysis.
T2  - Journal of the Serbian Chemical Society
T1  - Comparison of non-destructive techniques and conventionally used spectrometric techniques for determination of elements in plant samples (coniferous leaves)
VL  - 87
IS  - 1
SP  - 69
EP  - 81
DO  - 10.2298/JSC210921101O
ER  - 
@article{
author = "Orlić, Jovana and Aničić-Urošević, Mira and Vergel, Konstantin and Zinicovscaia, Inga and Stojadinović, Sanja and Gržetić, Ivan and Ilijević, Konstantin",
year = "2022",
abstract = "Conventionally used spectrometric techniques of inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma optical emission spectrometry (ICP-MS) usually involve time-consuming sample preparation procedure of a sample dissolution which requires the usage of aggressive and toxic chemicals. The need for suitable and sustainable analytical methods for direct multi-elemental analysis of plant samples has been increased in recent years. Spectrometric techniques for direct sample analysis, instrumental neutron activation analysis (INAA) and X-ray fluorescence (XRF) have been applied in environmental studies and various fields of screening tests. Nevertheless, these techniques are not commonly used for plant sample analysis and their performances need to be evaluated. This research aimed to assess how reliable non-destructive techniques are in the determination of elements in plants compared to conventionally used spectrometric techniques. A total of 49 plant samples of four conifer species (Pinus nigra, Abies alba, Taxus baccata and Larix decidua) were measured using two conventionally applied (ICP-MS, ICP-OES) and two non-destructive techniques (wavelength dispersive XRF (WD-XRF), INAA). The comparison was performed by investigation of relative ratios of concentrations and by correlation analysis. Moreover, precision of the techniques was examined and compared. The quality control included analysis of NIST pine needles certified reference material (1575a) using all examined techniques. Our results suggest that additional analytical and quality control steps are necessary for reaching the highest accuracy of multi-elemental analysis.",
journal = "Journal of the Serbian Chemical Society",
title = "Comparison of non-destructive techniques and conventionally used spectrometric techniques for determination of elements in plant samples (coniferous leaves)",
volume = "87",
number = "1",
pages = "69-81",
doi = "10.2298/JSC210921101O"
}
Orlić, J., Aničić-Urošević, M., Vergel, K., Zinicovscaia, I., Stojadinović, S., Gržetić, I.,& Ilijević, K.. (2022). Comparison of non-destructive techniques and conventionally used spectrometric techniques for determination of elements in plant samples (coniferous leaves). in Journal of the Serbian Chemical Society, 87(1), 69-81.
https://doi.org/10.2298/JSC210921101O
Orlić J, Aničić-Urošević M, Vergel K, Zinicovscaia I, Stojadinović S, Gržetić I, Ilijević K. Comparison of non-destructive techniques and conventionally used spectrometric techniques for determination of elements in plant samples (coniferous leaves). in Journal of the Serbian Chemical Society. 2022;87(1):69-81.
doi:10.2298/JSC210921101O .
Orlić, Jovana, Aničić-Urošević, Mira, Vergel, Konstantin, Zinicovscaia, Inga, Stojadinović, Sanja, Gržetić, Ivan, Ilijević, Konstantin, "Comparison of non-destructive techniques and conventionally used spectrometric techniques for determination of elements in plant samples (coniferous leaves)" in Journal of the Serbian Chemical Society, 87, no. 1 (2022):69-81,
https://doi.org/10.2298/JSC210921101O . .

Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity

Stevanović, Nevena; Zlatar, Matija; Novaković, Irena T.; Pevec, Andrej; Radanović, Dušanka; Matić, Ivana Z.; Đorđić Crnogorac, Marija; Stanojković, Tatjana; Vujčić, Miroslava; Gruden, Maja; Sladić, Dušan; Anđelković, Katarina; Turel, Iztok; Čobeljić, Božidar

(Royal Society of Chemistry (RSC), 2022)

TY  - JOUR
AU  - Stevanović, Nevena
AU  - Zlatar, Matija
AU  - Novaković, Irena T.
AU  - Pevec, Andrej
AU  - Radanović, Dušanka
AU  - Matić, Ivana Z.
AU  - Đorđić Crnogorac, Marija
AU  - Stanojković, Tatjana
AU  - Vujčić, Miroslava
AU  - Gruden, Maja
AU  - Sladić, Dušan
AU  - Anđelković, Katarina
AU  - Turel, Iztok
AU  - Čobeljić, Božidar
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4857
AB  - In this paper, Cu(II), Mn(II) and Zn(II) complexes with N,N,N-trimethyl-2-oxo-2-(2-(1-(thiazol-2-yl)ethylidene)hydrazinyl)ethan-1-aminium chloride (HL1Cl) were synthesized and characterized by single-crystal X-ray diffraction, IR spectroscopy, elemental analysis and DFT calculations. In all three complexes, a ligand (L1) is coordinated in a deprotonated formally neutral zwitterionic form via NNO donor set atoms. Cu(II) and Zn(II) form mononuclear penta-coordinated complexes [CuL1(N3)(CH3OH)]BF4 and [ZnL1(N3)2], respectively, while Mn(II) forms a binuclear [Mn2L12(μ-1,1-N3)2(N3)2]·2CH3OH complex, with unusual distorted trigonal-prismatic geometry around the metal centers. The antimicrobial activity of these complexes was tested against a panel of Gram-negative and Gram-positive bacteria, two yeasts and one fungal strain. The binuclear Mn(II) complex showed antifungal activity of similar intensity to amphotericin B. Based on the results of the brine shrimp test and DPPH radical scavenging activity, the most active Cu(II) and Mn(II) complexes were selected for evaluation of cytotoxic activity against five malignant cancer cell lines (HeLa, A375, MCF7, PC-3 and A549) and one normal cell line HaCaT. Both complexes showed significant activity. It should be pointed out that the activity of the Mn(II) complex against the MCF7 breast cancer cell line is only slightly weaker than that of cisplatin, but with selectivity to the tumor cell line in comparison to normal HaCaT cells, which is non-existent in the case of cisplatin.
PB  - Royal Society of Chemistry (RSC)
T2  - Dalton Transactions
T1  - Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity
VL  - 51
IS  - 1
SP  - 185
EP  - 196
DO  - 10.1039/D1DT03169D
ER  - 
@article{
author = "Stevanović, Nevena and Zlatar, Matija and Novaković, Irena T. and Pevec, Andrej and Radanović, Dušanka and Matić, Ivana Z. and Đorđić Crnogorac, Marija and Stanojković, Tatjana and Vujčić, Miroslava and Gruden, Maja and Sladić, Dušan and Anđelković, Katarina and Turel, Iztok and Čobeljić, Božidar",
year = "2022",
abstract = "In this paper, Cu(II), Mn(II) and Zn(II) complexes with N,N,N-trimethyl-2-oxo-2-(2-(1-(thiazol-2-yl)ethylidene)hydrazinyl)ethan-1-aminium chloride (HL1Cl) were synthesized and characterized by single-crystal X-ray diffraction, IR spectroscopy, elemental analysis and DFT calculations. In all three complexes, a ligand (L1) is coordinated in a deprotonated formally neutral zwitterionic form via NNO donor set atoms. Cu(II) and Zn(II) form mononuclear penta-coordinated complexes [CuL1(N3)(CH3OH)]BF4 and [ZnL1(N3)2], respectively, while Mn(II) forms a binuclear [Mn2L12(μ-1,1-N3)2(N3)2]·2CH3OH complex, with unusual distorted trigonal-prismatic geometry around the metal centers. The antimicrobial activity of these complexes was tested against a panel of Gram-negative and Gram-positive bacteria, two yeasts and one fungal strain. The binuclear Mn(II) complex showed antifungal activity of similar intensity to amphotericin B. Based on the results of the brine shrimp test and DPPH radical scavenging activity, the most active Cu(II) and Mn(II) complexes were selected for evaluation of cytotoxic activity against five malignant cancer cell lines (HeLa, A375, MCF7, PC-3 and A549) and one normal cell line HaCaT. Both complexes showed significant activity. It should be pointed out that the activity of the Mn(II) complex against the MCF7 breast cancer cell line is only slightly weaker than that of cisplatin, but with selectivity to the tumor cell line in comparison to normal HaCaT cells, which is non-existent in the case of cisplatin.",
publisher = "Royal Society of Chemistry (RSC)",
journal = "Dalton Transactions",
title = "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity",
volume = "51",
number = "1",
pages = "185-196",
doi = "10.1039/D1DT03169D"
}
Stevanović, N., Zlatar, M., Novaković, I. T., Pevec, A., Radanović, D., Matić, I. Z., Đorđić Crnogorac, M., Stanojković, T., Vujčić, M., Gruden, M., Sladić, D., Anđelković, K., Turel, I.,& Čobeljić, B.. (2022). Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity. in Dalton Transactions
Royal Society of Chemistry (RSC)., 51(1), 185-196.
https://doi.org/10.1039/D1DT03169D
Stevanović N, Zlatar M, Novaković IT, Pevec A, Radanović D, Matić IZ, Đorđić Crnogorac M, Stanojković T, Vujčić M, Gruden M, Sladić D, Anđelković K, Turel I, Čobeljić B. Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity. in Dalton Transactions. 2022;51(1):185-196.
doi:10.1039/D1DT03169D .
Stevanović, Nevena, Zlatar, Matija, Novaković, Irena T., Pevec, Andrej, Radanović, Dušanka, Matić, Ivana Z., Đorđić Crnogorac, Marija, Stanojković, Tatjana, Vujčić, Miroslava, Gruden, Maja, Sladić, Dušan, Anđelković, Katarina, Turel, Iztok, Čobeljić, Božidar, "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity" in Dalton Transactions, 51, no. 1 (2022):185-196,
https://doi.org/10.1039/D1DT03169D . .
4
1
1

Supporting information for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"

Stevanović, Nevena; Zlatar, Matija; Novaković, Irena T.; Pevec, Andrej; Radanović, Dušanka; Matić, Ivana Z.; Đorđić Crnogorac, Marija; Stanojković, Tatjana; Vujčić, Miroslava; Gruden, Maja; Sladić, Dušan; Anđelković, Katarina; Turel, Iztok; Čobeljić, Božidar

(Royal Society of Chemistry (RSC), 2022)

TY  - DATA
AU  - Stevanović, Nevena
AU  - Zlatar, Matija
AU  - Novaković, Irena T.
AU  - Pevec, Andrej
AU  - Radanović, Dušanka
AU  - Matić, Ivana Z.
AU  - Đorđić Crnogorac, Marija
AU  - Stanojković, Tatjana
AU  - Vujčić, Miroslava
AU  - Gruden, Maja
AU  - Sladić, Dušan
AU  - Anđelković, Katarina
AU  - Turel, Iztok
AU  - Čobeljić, Božidar
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4858
AB  - In this paper, Cu(II), Mn(II) and Zn(II) complexes with N,N,N-trimethyl-2-oxo-2-(2-(1-(thiazol-2-yl)ethylidene)hydrazinyl)ethan-1-aminium chloride (HL1Cl) were synthesized and characterized by single-crystal X-ray diffraction, IR spectroscopy, elemental analysis and DFT calculations. In all three complexes, a ligand (L1) is coordinated in a deprotonated formally neutral zwitterionic form via NNO donor set atoms. Cu(II) and Zn(II) form mononuclear penta-coordinated complexes [CuL1(N3)(CH3OH)]BF4 and [ZnL1(N3)2], respectively, while Mn(II) forms a binuclear [Mn2L12(μ-1,1-N3)2(N3)2]·2CH3OH complex, with unusual distorted trigonal-prismatic geometry around the metal centers. The antimicrobial activity of these complexes was tested against a panel of Gram-negative and Gram-positive bacteria, two yeasts and one fungal strain. The binuclear Mn(II) complex showed antifungal activity of similar intensity to amphotericin B. Based on the results of the brine shrimp test and DPPH radical scavenging activity, the most active Cu(II) and Mn(II) complexes were selected for evaluation of cytotoxic activity against five malignant cancer cell lines (HeLa, A375, MCF7, PC-3 and A549) and one normal cell line HaCaT. Both complexes showed significant activity. It should be pointed out that the activity of the Mn(II) complex against the MCF7 breast cancer cell line is only slightly weaker than that of cisplatin, but with selectivity to the tumor cell line in comparison to normal HaCaT cells, which is non-existent in the case of cisplatin.
PB  - Royal Society of Chemistry (RSC)
T2  - Dalton Transactions
T1  - Supporting information for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4858
ER  - 
@misc{
author = "Stevanović, Nevena and Zlatar, Matija and Novaković, Irena T. and Pevec, Andrej and Radanović, Dušanka and Matić, Ivana Z. and Đorđić Crnogorac, Marija and Stanojković, Tatjana and Vujčić, Miroslava and Gruden, Maja and Sladić, Dušan and Anđelković, Katarina and Turel, Iztok and Čobeljić, Božidar",
year = "2022",
abstract = "In this paper, Cu(II), Mn(II) and Zn(II) complexes with N,N,N-trimethyl-2-oxo-2-(2-(1-(thiazol-2-yl)ethylidene)hydrazinyl)ethan-1-aminium chloride (HL1Cl) were synthesized and characterized by single-crystal X-ray diffraction, IR spectroscopy, elemental analysis and DFT calculations. In all three complexes, a ligand (L1) is coordinated in a deprotonated formally neutral zwitterionic form via NNO donor set atoms. Cu(II) and Zn(II) form mononuclear penta-coordinated complexes [CuL1(N3)(CH3OH)]BF4 and [ZnL1(N3)2], respectively, while Mn(II) forms a binuclear [Mn2L12(μ-1,1-N3)2(N3)2]·2CH3OH complex, with unusual distorted trigonal-prismatic geometry around the metal centers. The antimicrobial activity of these complexes was tested against a panel of Gram-negative and Gram-positive bacteria, two yeasts and one fungal strain. The binuclear Mn(II) complex showed antifungal activity of similar intensity to amphotericin B. Based on the results of the brine shrimp test and DPPH radical scavenging activity, the most active Cu(II) and Mn(II) complexes were selected for evaluation of cytotoxic activity against five malignant cancer cell lines (HeLa, A375, MCF7, PC-3 and A549) and one normal cell line HaCaT. Both complexes showed significant activity. It should be pointed out that the activity of the Mn(II) complex against the MCF7 breast cancer cell line is only slightly weaker than that of cisplatin, but with selectivity to the tumor cell line in comparison to normal HaCaT cells, which is non-existent in the case of cisplatin.",
publisher = "Royal Society of Chemistry (RSC)",
journal = "Dalton Transactions",
title = "Supporting information for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4858"
}
Stevanović, N., Zlatar, M., Novaković, I. T., Pevec, A., Radanović, D., Matić, I. Z., Đorđić Crnogorac, M., Stanojković, T., Vujčić, M., Gruden, M., Sladić, D., Anđelković, K., Turel, I.,& Čobeljić, B.. (2022). Supporting information for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity". in Dalton Transactions
Royal Society of Chemistry (RSC)..
https://hdl.handle.net/21.15107/rcub_cherry_4858
Stevanović N, Zlatar M, Novaković IT, Pevec A, Radanović D, Matić IZ, Đorđić Crnogorac M, Stanojković T, Vujčić M, Gruden M, Sladić D, Anđelković K, Turel I, Čobeljić B. Supporting information for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity". in Dalton Transactions. 2022;.
https://hdl.handle.net/21.15107/rcub_cherry_4858 .
Stevanović, Nevena, Zlatar, Matija, Novaković, Irena T., Pevec, Andrej, Radanović, Dušanka, Matić, Ivana Z., Đorđić Crnogorac, Marija, Stanojković, Tatjana, Vujčić, Miroslava, Gruden, Maja, Sladić, Dušan, Anđelković, Katarina, Turel, Iztok, Čobeljić, Božidar, "Supporting information for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"" in Dalton Transactions (2022),
https://hdl.handle.net/21.15107/rcub_cherry_4858 .

CCDC 2110386: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"

Pevec, Andrej

(The Cambridge Crystallographic Data Centre (CCDC), 2022)

TY  - DATA
AU  - Pevec, Andrej
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4859
AB  - NAMYIN : azido-[2-oxy-N,N,N-trimethyl-2-{[1-(1,3-thiazol-2-yl)ethylidene]hydrazinylidene}ethan-1-aminium]-(methanol)-copper tetrafluoroborate Space Group: P 21/n (14), Cell: a 7.0033(3)Å b 10.8941(3)Å c 25.6059(9)Å, α 90° β 97.242(4)° γ 90°
PB  - The Cambridge Crystallographic Data Centre (CCDC)
T1  - CCDC 2110386: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"
DO  - 10.5517/ccdc.csd.cc28v0z4
ER  - 
@misc{
author = "Pevec, Andrej",
year = "2022",
abstract = "NAMYIN : azido-[2-oxy-N,N,N-trimethyl-2-{[1-(1,3-thiazol-2-yl)ethylidene]hydrazinylidene}ethan-1-aminium]-(methanol)-copper tetrafluoroborate Space Group: P 21/n (14), Cell: a 7.0033(3)Å b 10.8941(3)Å c 25.6059(9)Å, α 90° β 97.242(4)° γ 90°",
publisher = "The Cambridge Crystallographic Data Centre (CCDC)",
title = "CCDC 2110386: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"",
doi = "10.5517/ccdc.csd.cc28v0z4"
}
Pevec, A.. (2022). CCDC 2110386: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity". 
The Cambridge Crystallographic Data Centre (CCDC)..
https://doi.org/10.5517/ccdc.csd.cc28v0z4
Pevec A. CCDC 2110386: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity". 2022;.
doi:10.5517/ccdc.csd.cc28v0z4 .
Pevec, Andrej, "CCDC 2110386: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"" (2022),
https://doi.org/10.5517/ccdc.csd.cc28v0z4 . .

CCDC 2110387: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"

Pevec, Andrej

(The Cambridge Crystallographic Data Centre (CCDC), 2022)

TY  - DATA
AU  - Pevec, Andrej
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4860
AB  - NAMYOT : bis(μ-azido)-diazido-bis[2-oxy-N,N,N-trimethyl-2-{[1-(1,3-thiazol-2-yl)ethylidene]hydrazinylidene}ethan-1-aminium]-di-manganese methanol solvate Space Group: P 1 (2), Cell: a 9.6427(5)Å b 10.8396(5)Å c 10.8617(8)Å, α 106.971(5)° β 103.497(5)° γ 112.469(5)°
PB  - The Cambridge Crystallographic Data Centre (CCDC)
T1  - CCDC 2110387: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"
DO  - 10.5517/ccdc.csd.cc28v106
ER  - 
@misc{
author = "Pevec, Andrej",
year = "2022",
abstract = "NAMYOT : bis(μ-azido)-diazido-bis[2-oxy-N,N,N-trimethyl-2-{[1-(1,3-thiazol-2-yl)ethylidene]hydrazinylidene}ethan-1-aminium]-di-manganese methanol solvate Space Group: P 1 (2), Cell: a 9.6427(5)Å b 10.8396(5)Å c 10.8617(8)Å, α 106.971(5)° β 103.497(5)° γ 112.469(5)°",
publisher = "The Cambridge Crystallographic Data Centre (CCDC)",
title = "CCDC 2110387: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"",
doi = "10.5517/ccdc.csd.cc28v106"
}
Pevec, A.. (2022). CCDC 2110387: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity". 
The Cambridge Crystallographic Data Centre (CCDC)..
https://doi.org/10.5517/ccdc.csd.cc28v106
Pevec A. CCDC 2110387: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity". 2022;.
doi:10.5517/ccdc.csd.cc28v106 .
Pevec, Andrej, "CCDC 2110387: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"" (2022),
https://doi.org/10.5517/ccdc.csd.cc28v106 . .

CCDC 2110388: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"

Pevec, Andrej

(The Cambridge Crystallographic Data Centre (CCDC), 2022)

TY  - DATA
AU  - Pevec, Andrej
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4861
AB  - NAMYUZ : diazido-[2-oxy-N,N,N-trimethyl-2-{[1-(1,3-thiazol-2-yl)ethylidene]hydrazinylidene}ethan-1-aminium]-zinc Space Group: P 21/c (14), Cell: a 13.0826(10)Å b 10.2506(7)Å c 13.1685(13)Å, α 90° β 111.237(10)° γ 90°
PB  - The Cambridge Crystallographic Data Centre (CCDC)
T1  - CCDC 2110388: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"
DO  - 10.5517/ccdc.csd.cc28v117
ER  - 
@misc{
author = "Pevec, Andrej",
year = "2022",
abstract = "NAMYUZ : diazido-[2-oxy-N,N,N-trimethyl-2-{[1-(1,3-thiazol-2-yl)ethylidene]hydrazinylidene}ethan-1-aminium]-zinc Space Group: P 21/c (14), Cell: a 13.0826(10)Å b 10.2506(7)Å c 13.1685(13)Å, α 90° β 111.237(10)° γ 90°",
publisher = "The Cambridge Crystallographic Data Centre (CCDC)",
title = "CCDC 2110388: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"",
doi = "10.5517/ccdc.csd.cc28v117"
}
Pevec, A.. (2022). CCDC 2110388: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity". 
The Cambridge Crystallographic Data Centre (CCDC)..
https://doi.org/10.5517/ccdc.csd.cc28v117
Pevec A. CCDC 2110388: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity". 2022;.
doi:10.5517/ccdc.csd.cc28v117 .
Pevec, Andrej, "CCDC 2110388: Experimental Crystal Structure Determination. Crystallographic data for: "Cu(II), Mn(II) and Zn(II) complexes of hydrazones with a quaternary ammonium moiety: synthesis, experimental and theoretical characterization and cytotoxic activity"" (2022),
https://doi.org/10.5517/ccdc.csd.cc28v117 . .

To Professor Petar Pfendt, In calidum, et plurium retributivus memoriae: FTIR-ATR analysis of post stamps of the Principality of Serbia issued in 1866 and 1868 and their forgeries

Popović, Aleksandar R.; Anđelković, Boban; Đorđević, Dragana; Sakan, Sanja; Vujisić, Ljubodrag V.; Veličković, Sava; Relić, Dubravka

(2022)

TY  - JOUR
AU  - Popović, Aleksandar R.
AU  - Anđelković, Boban
AU  - Đorđević, Dragana
AU  - Sakan, Sanja
AU  - Vujisić, Ljubodrag V.
AU  - Veličković, Sava
AU  - Relić, Dubravka
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4942
AB  - In order to further define the potential use of FTIR-ATR spectroscopy, as a non-destructive and reliable technique, for the analysis of the characteristics of post stamps, certified originals of the Principality of Serbia stamps (“Prince Michael issues”) issued in 1866 and 1868 as well as their forgeries were ana­lyzed. Spectra enabling the comparison of the paper, dye and glue of stamps of so-called “Vienna issues”, having denominations of 10 (orange-yellow), 20 (pink) and 40 para (blue) and “Belgrade issues” (1 para-green and 2 para-reddish brown), as well as 24 expert-certified forgeries, were taken. It was shown that the applied technology was, in most of the cases, a fast and suitable technique for establishing clear differences between the spectral characteristics of the paper and dye used for the original stamps, and forgeries that were most probably made decades after the printing of the genuine stamps. The differences between print­ings of the same issues of the genuine stamps were also elaborated. It is pro­posed, for the first time in philatelic history, the possibility that “Vienna issues” stamps may have been printed on two different papers, and, having in mind the technology of printing in the 19th century, potentially, not even at the same time or in the same printing house.
T2  - Journal of the Serbian Chemical Society
T1  - To Professor Petar Pfendt, In calidum, et plurium retributivus memoriae: FTIR-ATR analysis of post stamps of the Principality of Serbia issued in 1866 and 1868 and their forgeries
VL  - 87
IS  - 1
SP  - 27
EP  - 40
DO  - 10.2298/JSC210901090P
ER  - 
@article{
author = "Popović, Aleksandar R. and Anđelković, Boban and Đorđević, Dragana and Sakan, Sanja and Vujisić, Ljubodrag V. and Veličković, Sava and Relić, Dubravka",
year = "2022",
abstract = "In order to further define the potential use of FTIR-ATR spectroscopy, as a non-destructive and reliable technique, for the analysis of the characteristics of post stamps, certified originals of the Principality of Serbia stamps (“Prince Michael issues”) issued in 1866 and 1868 as well as their forgeries were ana­lyzed. Spectra enabling the comparison of the paper, dye and glue of stamps of so-called “Vienna issues”, having denominations of 10 (orange-yellow), 20 (pink) and 40 para (blue) and “Belgrade issues” (1 para-green and 2 para-reddish brown), as well as 24 expert-certified forgeries, were taken. It was shown that the applied technology was, in most of the cases, a fast and suitable technique for establishing clear differences between the spectral characteristics of the paper and dye used for the original stamps, and forgeries that were most probably made decades after the printing of the genuine stamps. The differences between print­ings of the same issues of the genuine stamps were also elaborated. It is pro­posed, for the first time in philatelic history, the possibility that “Vienna issues” stamps may have been printed on two different papers, and, having in mind the technology of printing in the 19th century, potentially, not even at the same time or in the same printing house.",
journal = "Journal of the Serbian Chemical Society",
title = "To Professor Petar Pfendt, In calidum, et plurium retributivus memoriae: FTIR-ATR analysis of post stamps of the Principality of Serbia issued in 1866 and 1868 and their forgeries",
volume = "87",
number = "1",
pages = "27-40",
doi = "10.2298/JSC210901090P"
}
Popović, A. R., Anđelković, B., Đorđević, D., Sakan, S., Vujisić, L. V., Veličković, S.,& Relić, D.. (2022). To Professor Petar Pfendt, In calidum, et plurium retributivus memoriae: FTIR-ATR analysis of post stamps of the Principality of Serbia issued in 1866 and 1868 and their forgeries. in Journal of the Serbian Chemical Society, 87(1), 27-40.
https://doi.org/10.2298/JSC210901090P
Popović AR, Anđelković B, Đorđević D, Sakan S, Vujisić LV, Veličković S, Relić D. To Professor Petar Pfendt, In calidum, et plurium retributivus memoriae: FTIR-ATR analysis of post stamps of the Principality of Serbia issued in 1866 and 1868 and their forgeries. in Journal of the Serbian Chemical Society. 2022;87(1):27-40.
doi:10.2298/JSC210901090P .
Popović, Aleksandar R., Anđelković, Boban, Đorđević, Dragana, Sakan, Sanja, Vujisić, Ljubodrag V., Veličković, Sava, Relić, Dubravka, "To Professor Petar Pfendt, In calidum, et plurium retributivus memoriae: FTIR-ATR analysis of post stamps of the Principality of Serbia issued in 1866 and 1868 and their forgeries" in Journal of the Serbian Chemical Society, 87, no. 1 (2022):27-40,
https://doi.org/10.2298/JSC210901090P . .

A comparative study of the molecular and isotopic composition of biomarkers in immature oil shale (Aleksinac deposit, Serbia) and its liquid pyrolysis products (open and closed systems)

Gajica, Gordana; Šajnović, Aleksandra; Stojanović, Ksenija A.; Schwarzbauer, Jan; Kostić, Aleksandar; Jovančićević, Branimir

(Elsevier, 2022)

TY  - JOUR
AU  - Gajica, Gordana
AU  - Šajnović, Aleksandra
AU  - Stojanović, Ksenija A.
AU  - Schwarzbauer, Jan
AU  - Kostić, Aleksandar
AU  - Jovančićević, Branimir
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4846
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4847
AB  - The molecular and isotopic composition of biomarkers in initial bitumen isolated from immature (0.41% Rr) oil shale samples (Aleksinac deposit) and liquid products obtained by pyrolysis in open (OS) and closed (CS) systems are studied. The influence of pyrolysis type and variations of kerogen type on biomarkers composition and their isotopic signatures in liquid products is determined. The applicability of pyrolysis type, numerous biomarkers and carbon isotopic compositions (δ13C) of n-alkanes in liquid pyrolysates is established. Pyrolysis experiments were performed on two selected samples that showed high content of total organic carbon and hydrocarbon generation potential, but also certain variations in sources/depositional environment of organic matter (type I and mixed type I/II kerogen) within previous research of the oil shales sample set. The biomarker signatures were evaluated using gas chromatography-mass spectrometry (GC-MS) and δ13C of individual n-alkanes in bitumen and liquid pyrolysates. The molecular composition of liquid pyrolysates from the OS is very similar to those in initial bitumen, independently on kerogen type, confirming algal origin of organic matter (OM) deposited in lacustrine environment, even more apparently than results of initial bitumen. Therefore, OS can be useful for assessment of source and depositional environment of OM. Pyrolysis in the CS caused more intense thermal alterations, therefore the source fingerprints sometimes notably disappear. The liquid pyrolysates from the CS have the distributions of biomarkers similar to those in crude oils. The biomarker maturity parameters showed slightly higher values in the CS pyrolysate of mixed type I/II kerogen in relation to type I kerogen. δ13C of n-alkanes in liquid pyrolysates from the OS are isotopically lighter in comparison to bitumen, independently on kerogen type. Oppositely, in liquid pyrolysates from the CS, they become heavier than in bitumen, indicating the thermal influence on δ13C signatures, with more pronounced difference for type I kerogen.
PB  - Elsevier
T2  - Marine and Petroleum Geology
T1  - A comparative study of the molecular and isotopic composition of biomarkers in immature oil shale (Aleksinac deposit, Serbia) and its liquid pyrolysis products (open and closed systems)
VL  - 136
SP  - 105383
DO  - 10.1016/j.marpetgeo.2021.105383
ER  - 
@article{
author = "Gajica, Gordana and Šajnović, Aleksandra and Stojanović, Ksenija A. and Schwarzbauer, Jan and Kostić, Aleksandar and Jovančićević, Branimir",
year = "2022",
abstract = "The molecular and isotopic composition of biomarkers in initial bitumen isolated from immature (0.41% Rr) oil shale samples (Aleksinac deposit) and liquid products obtained by pyrolysis in open (OS) and closed (CS) systems are studied. The influence of pyrolysis type and variations of kerogen type on biomarkers composition and their isotopic signatures in liquid products is determined. The applicability of pyrolysis type, numerous biomarkers and carbon isotopic compositions (δ13C) of n-alkanes in liquid pyrolysates is established. Pyrolysis experiments were performed on two selected samples that showed high content of total organic carbon and hydrocarbon generation potential, but also certain variations in sources/depositional environment of organic matter (type I and mixed type I/II kerogen) within previous research of the oil shales sample set. The biomarker signatures were evaluated using gas chromatography-mass spectrometry (GC-MS) and δ13C of individual n-alkanes in bitumen and liquid pyrolysates. The molecular composition of liquid pyrolysates from the OS is very similar to those in initial bitumen, independently on kerogen type, confirming algal origin of organic matter (OM) deposited in lacustrine environment, even more apparently than results of initial bitumen. Therefore, OS can be useful for assessment of source and depositional environment of OM. Pyrolysis in the CS caused more intense thermal alterations, therefore the source fingerprints sometimes notably disappear. The liquid pyrolysates from the CS have the distributions of biomarkers similar to those in crude oils. The biomarker maturity parameters showed slightly higher values in the CS pyrolysate of mixed type I/II kerogen in relation to type I kerogen. δ13C of n-alkanes in liquid pyrolysates from the OS are isotopically lighter in comparison to bitumen, independently on kerogen type. Oppositely, in liquid pyrolysates from the CS, they become heavier than in bitumen, indicating the thermal influence on δ13C signatures, with more pronounced difference for type I kerogen.",
publisher = "Elsevier",
journal = "Marine and Petroleum Geology",
title = "A comparative study of the molecular and isotopic composition of biomarkers in immature oil shale (Aleksinac deposit, Serbia) and its liquid pyrolysis products (open and closed systems)",
volume = "136",
pages = "105383",
doi = "10.1016/j.marpetgeo.2021.105383"
}
Gajica, G., Šajnović, A., Stojanović, K. A., Schwarzbauer, J., Kostić, A.,& Jovančićević, B.. (2022). A comparative study of the molecular and isotopic composition of biomarkers in immature oil shale (Aleksinac deposit, Serbia) and its liquid pyrolysis products (open and closed systems). in Marine and Petroleum Geology
Elsevier., 136, 105383.
https://doi.org/10.1016/j.marpetgeo.2021.105383
Gajica G, Šajnović A, Stojanović KA, Schwarzbauer J, Kostić A, Jovančićević B. A comparative study of the molecular and isotopic composition of biomarkers in immature oil shale (Aleksinac deposit, Serbia) and its liquid pyrolysis products (open and closed systems). in Marine and Petroleum Geology. 2022;136:105383.
doi:10.1016/j.marpetgeo.2021.105383 .
Gajica, Gordana, Šajnović, Aleksandra, Stojanović, Ksenija A., Schwarzbauer, Jan, Kostić, Aleksandar, Jovančićević, Branimir, "A comparative study of the molecular and isotopic composition of biomarkers in immature oil shale (Aleksinac deposit, Serbia) and its liquid pyrolysis products (open and closed systems)" in Marine and Petroleum Geology, 136 (2022):105383,
https://doi.org/10.1016/j.marpetgeo.2021.105383 . .

A comparative study of the molecular and isotopic composition of biomarkers in immature oil shale (Aleksinac deposit, Serbia) and its liquid pyrolysis products (open and closed systems)

Gajica, Gordana; Šajnović, Aleksandra; Stojanović, Ksenija A.; Schwarzbauer, Jan; Kostić, Aleksandar; Jovančićević, Branimir

(Elsevier, 2022)

TY  - JOUR
AU  - Gajica, Gordana
AU  - Šajnović, Aleksandra
AU  - Stojanović, Ksenija A.
AU  - Schwarzbauer, Jan
AU  - Kostić, Aleksandar
AU  - Jovančićević, Branimir
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4846
AB  - The molecular and isotopic composition of biomarkers in initial bitumen isolated from immature (0.41% Rr) oil shale samples (Aleksinac deposit) and liquid products obtained by pyrolysis in open (OS) and closed (CS) systems are studied. The influence of pyrolysis type and variations of kerogen type on biomarkers composition and their isotopic signatures in liquid products is determined. The applicability of pyrolysis type, numerous biomarkers and carbon isotopic compositions (δ13C) of n-alkanes in liquid pyrolysates is established. Pyrolysis experiments were performed on two selected samples that showed high content of total organic carbon and hydrocarbon generation potential, but also certain variations in sources/depositional environment of organic matter (type I and mixed type I/II kerogen) within previous research of the oil shales sample set. The biomarker signatures were evaluated using gas chromatography-mass spectrometry (GC-MS) and δ13C of individual n-alkanes in bitumen and liquid pyrolysates. The molecular composition of liquid pyrolysates from the OS is very similar to those in initial bitumen, independently on kerogen type, confirming algal origin of organic matter (OM) deposited in lacustrine environment, even more apparently than results of initial bitumen. Therefore, OS can be useful for assessment of source and depositional environment of OM. Pyrolysis in the CS caused more intense thermal alterations, therefore the source fingerprints sometimes notably disappear. The liquid pyrolysates from the CS have the distributions of biomarkers similar to those in crude oils. The biomarker maturity parameters showed slightly higher values in the CS pyrolysate of mixed type I/II kerogen in relation to type I kerogen. δ13C of n-alkanes in liquid pyrolysates from the OS are isotopically lighter in comparison to bitumen, independently on kerogen type. Oppositely, in liquid pyrolysates from the CS, they become heavier than in bitumen, indicating the thermal influence on δ13C signatures, with more pronounced difference for type I kerogen.
PB  - Elsevier
T2  - Marine and Petroleum Geology
T1  - A comparative study of the molecular and isotopic composition of biomarkers in immature oil shale (Aleksinac deposit, Serbia) and its liquid pyrolysis products (open and closed systems)
VL  - 136
SP  - 105383
DO  - 10.1016/j.marpetgeo.2021.105383
ER  - 
@article{
author = "Gajica, Gordana and Šajnović, Aleksandra and Stojanović, Ksenija A. and Schwarzbauer, Jan and Kostić, Aleksandar and Jovančićević, Branimir",
year = "2022",
abstract = "The molecular and isotopic composition of biomarkers in initial bitumen isolated from immature (0.41% Rr) oil shale samples (Aleksinac deposit) and liquid products obtained by pyrolysis in open (OS) and closed (CS) systems are studied. The influence of pyrolysis type and variations of kerogen type on biomarkers composition and their isotopic signatures in liquid products is determined. The applicability of pyrolysis type, numerous biomarkers and carbon isotopic compositions (δ13C) of n-alkanes in liquid pyrolysates is established. Pyrolysis experiments were performed on two selected samples that showed high content of total organic carbon and hydrocarbon generation potential, but also certain variations in sources/depositional environment of organic matter (type I and mixed type I/II kerogen) within previous research of the oil shales sample set. The biomarker signatures were evaluated using gas chromatography-mass spectrometry (GC-MS) and δ13C of individual n-alkanes in bitumen and liquid pyrolysates. The molecular composition of liquid pyrolysates from the OS is very similar to those in initial bitumen, independently on kerogen type, confirming algal origin of organic matter (OM) deposited in lacustrine environment, even more apparently than results of initial bitumen. Therefore, OS can be useful for assessment of source and depositional environment of OM. Pyrolysis in the CS caused more intense thermal alterations, therefore the source fingerprints sometimes notably disappear. The liquid pyrolysates from the CS have the distributions of biomarkers similar to those in crude oils. The biomarker maturity parameters showed slightly higher values in the CS pyrolysate of mixed type I/II kerogen in relation to type I kerogen. δ13C of n-alkanes in liquid pyrolysates from the OS are isotopically lighter in comparison to bitumen, independently on kerogen type. Oppositely, in liquid pyrolysates from the CS, they become heavier than in bitumen, indicating the thermal influence on δ13C signatures, with more pronounced difference for type I kerogen.",
publisher = "Elsevier",
journal = "Marine and Petroleum Geology",
title = "A comparative study of the molecular and isotopic composition of biomarkers in immature oil shale (Aleksinac deposit, Serbia) and its liquid pyrolysis products (open and closed systems)",
volume = "136",
pages = "105383",
doi = "10.1016/j.marpetgeo.2021.105383"
}
Gajica, G., Šajnović, A., Stojanović, K. A., Schwarzbauer, J., Kostić, A.,& Jovančićević, B.. (2022). A comparative study of the molecular and isotopic composition of biomarkers in immature oil shale (Aleksinac deposit, Serbia) and its liquid pyrolysis products (open and closed systems). in Marine and Petroleum Geology
Elsevier., 136, 105383.
https://doi.org/10.1016/j.marpetgeo.2021.105383
Gajica G, Šajnović A, Stojanović KA, Schwarzbauer J, Kostić A, Jovančićević B. A comparative study of the molecular and isotopic composition of biomarkers in immature oil shale (Aleksinac deposit, Serbia) and its liquid pyrolysis products (open and closed systems). in Marine and Petroleum Geology. 2022;136:105383.
doi:10.1016/j.marpetgeo.2021.105383 .
Gajica, Gordana, Šajnović, Aleksandra, Stojanović, Ksenija A., Schwarzbauer, Jan, Kostić, Aleksandar, Jovančićević, Branimir, "A comparative study of the molecular and isotopic composition of biomarkers in immature oil shale (Aleksinac deposit, Serbia) and its liquid pyrolysis products (open and closed systems)" in Marine and Petroleum Geology, 136 (2022):105383,
https://doi.org/10.1016/j.marpetgeo.2021.105383 . .

Unraveling the anti-virulence potential and antifungal efficacy of 5-aminotetrazoles using the zebrafish model of disseminated candidiasis

Radaković, Nataša; Nikolić, Andrea; Terzić Jovanović, Nataša; Stojković, Pavle; Stanković, Nada; Šolaja, Bogdan A.; Opsenica, Igor; Pavić, Aleksandar

(Elsevier, 2022)

TY  - JOUR
AU  - Radaković, Nataša
AU  - Nikolić, Andrea
AU  - Terzić Jovanović, Nataša
AU  - Stojković, Pavle
AU  - Stanković, Nada
AU  - Šolaja, Bogdan A.
AU  - Opsenica, Igor
AU  - Pavić, Aleksandar
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4877
AB  - Candida albicans remains the main causal agent of candidiasis, the most common fungal infection with disturbingly high mortality rates worldwide. The limited diversity and efficacy of clinical antifungal drugs, exacerbated by emerging drug resistance, have resulted in the failure of current antifungal therapies. This imposes an urgent demand for the development of innovative strategies for effective eradication of candidal infections. While the existing clinical drugs display fungicidal or fungistatic activity, the strategy specifically targeting C. albicans filamentation, as the most important virulence trait, represents an attractive approach for overcoming the drawbacks related to clinical antifungals. The results acquired in this study revealed the significant potential of 5-aminotetrazoles as a new class of effective and safe anti-virulence agents. Moreover, these novel agents were active when applied both alone and in combination with clinically approved polyenes. Complete prevention of C. albicans morphogenetic yeast-to-hyphae transition was achieved at doses as low as 1.3 μM under conditions mimicking various filamentation-responsive stimuli in the human body, while no cardio- or hepatotoxicity was observed at doses as high as 200 μM. The treatment of C. albicans-infected zebrafish embryos with nystatin alone had low efficacy, while the combination of nystatin and selected 5-aminotetrazoles prevented fungal filamentation, successfully eliminating the infection and rescuing the infected embryos from lethal disseminated candidiasis. In addition, the most potent anti-virulence 5-aminotetrazole prevented C. albicans in developing the resistance to nystatin when applied in combination, keeping the fungus sensitive to the antifungal drug.
PB  - Elsevier
T2  - European Journal of Medicinal Chemistry
T1  - Unraveling the anti-virulence potential and antifungal efficacy of 5-aminotetrazoles using the zebrafish model of disseminated candidiasis
VL  - 230
SP  - 114137
DO  - 10.1016/j.ejmech.2022.114137
ER  - 
@article{
author = "Radaković, Nataša and Nikolić, Andrea and Terzić Jovanović, Nataša and Stojković, Pavle and Stanković, Nada and Šolaja, Bogdan A. and Opsenica, Igor and Pavić, Aleksandar",
year = "2022",
abstract = "Candida albicans remains the main causal agent of candidiasis, the most common fungal infection with disturbingly high mortality rates worldwide. The limited diversity and efficacy of clinical antifungal drugs, exacerbated by emerging drug resistance, have resulted in the failure of current antifungal therapies. This imposes an urgent demand for the development of innovative strategies for effective eradication of candidal infections. While the existing clinical drugs display fungicidal or fungistatic activity, the strategy specifically targeting C. albicans filamentation, as the most important virulence trait, represents an attractive approach for overcoming the drawbacks related to clinical antifungals. The results acquired in this study revealed the significant potential of 5-aminotetrazoles as a new class of effective and safe anti-virulence agents. Moreover, these novel agents were active when applied both alone and in combination with clinically approved polyenes. Complete prevention of C. albicans morphogenetic yeast-to-hyphae transition was achieved at doses as low as 1.3 μM under conditions mimicking various filamentation-responsive stimuli in the human body, while no cardio- or hepatotoxicity was observed at doses as high as 200 μM. The treatment of C. albicans-infected zebrafish embryos with nystatin alone had low efficacy, while the combination of nystatin and selected 5-aminotetrazoles prevented fungal filamentation, successfully eliminating the infection and rescuing the infected embryos from lethal disseminated candidiasis. In addition, the most potent anti-virulence 5-aminotetrazole prevented C. albicans in developing the resistance to nystatin when applied in combination, keeping the fungus sensitive to the antifungal drug.",
publisher = "Elsevier",
journal = "European Journal of Medicinal Chemistry",
title = "Unraveling the anti-virulence potential and antifungal efficacy of 5-aminotetrazoles using the zebrafish model of disseminated candidiasis",
volume = "230",
pages = "114137",
doi = "10.1016/j.ejmech.2022.114137"
}
Radaković, N., Nikolić, A., Terzić Jovanović, N., Stojković, P., Stanković, N., Šolaja, B. A., Opsenica, I.,& Pavić, A.. (2022). Unraveling the anti-virulence potential and antifungal efficacy of 5-aminotetrazoles using the zebrafish model of disseminated candidiasis. in European Journal of Medicinal Chemistry
Elsevier., 230, 114137.
https://doi.org/10.1016/j.ejmech.2022.114137
Radaković N, Nikolić A, Terzić Jovanović N, Stojković P, Stanković N, Šolaja BA, Opsenica I, Pavić A. Unraveling the anti-virulence potential and antifungal efficacy of 5-aminotetrazoles using the zebrafish model of disseminated candidiasis. in European Journal of Medicinal Chemistry. 2022;230:114137.
doi:10.1016/j.ejmech.2022.114137 .
Radaković, Nataša, Nikolić, Andrea, Terzić Jovanović, Nataša, Stojković, Pavle, Stanković, Nada, Šolaja, Bogdan A., Opsenica, Igor, Pavić, Aleksandar, "Unraveling the anti-virulence potential and antifungal efficacy of 5-aminotetrazoles using the zebrafish model of disseminated candidiasis" in European Journal of Medicinal Chemistry, 230 (2022):114137,
https://doi.org/10.1016/j.ejmech.2022.114137 . .
2

Supplementary data for article: Radakovic, N.; Nikolić, A.; Jovanović, N. T.; Stojković, P.; Stankovic, N.; Šolaja, B.; Opsenica, I.; Pavic, A. Unraveling the Anti-Virulence Potential and Antifungal Efficacy of 5-Aminotetrazoles Using the Zebrafish Model of Disseminated Candidiasis. European Journal of Medicinal Chemistry 2022, 230, 114137. https://doi.org/10.1016/j.ejmech.2022.114137.

Radaković, Nataša; Nikolić, Andrea; Terzić Jovanović, Nataša; Stojković, Pavle; Stanković, Nada; Šolaja, Bogdan A.; Opsenica, Igor; Pavić, Aleksandar

(Elsevier, 2022)

TY  - DATA
AU  - Radaković, Nataša
AU  - Nikolić, Andrea
AU  - Terzić Jovanović, Nataša
AU  - Stojković, Pavle
AU  - Stanković, Nada
AU  - Šolaja, Bogdan A.
AU  - Opsenica, Igor
AU  - Pavić, Aleksandar
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4878
PB  - Elsevier
T2  - European Journal of Medicinal Chemistry
T1  - Supplementary data for article: Radakovic, N.; Nikolić, A.; Jovanović, N. T.; Stojković, P.; Stankovic, N.; Šolaja, B.; Opsenica, I.; Pavic, A. Unraveling the Anti-Virulence Potential and Antifungal Efficacy of 5-Aminotetrazoles Using the Zebrafish Model of Disseminated Candidiasis. European Journal of Medicinal Chemistry 2022, 230, 114137. https://doi.org/10.1016/j.ejmech.2022.114137.
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4878
ER  - 
@misc{
author = "Radaković, Nataša and Nikolić, Andrea and Terzić Jovanović, Nataša and Stojković, Pavle and Stanković, Nada and Šolaja, Bogdan A. and Opsenica, Igor and Pavić, Aleksandar",
year = "2022",
publisher = "Elsevier",
journal = "European Journal of Medicinal Chemistry",
title = "Supplementary data for article: Radakovic, N.; Nikolić, A.; Jovanović, N. T.; Stojković, P.; Stankovic, N.; Šolaja, B.; Opsenica, I.; Pavic, A. Unraveling the Anti-Virulence Potential and Antifungal Efficacy of 5-Aminotetrazoles Using the Zebrafish Model of Disseminated Candidiasis. European Journal of Medicinal Chemistry 2022, 230, 114137. https://doi.org/10.1016/j.ejmech.2022.114137.",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4878"
}
Radaković, N., Nikolić, A., Terzić Jovanović, N., Stojković, P., Stanković, N., Šolaja, B. A., Opsenica, I.,& Pavić, A.. (2022). Supplementary data for article: Radakovic, N.; Nikolić, A.; Jovanović, N. T.; Stojković, P.; Stankovic, N.; Šolaja, B.; Opsenica, I.; Pavic, A. Unraveling the Anti-Virulence Potential and Antifungal Efficacy of 5-Aminotetrazoles Using the Zebrafish Model of Disseminated Candidiasis. European Journal of Medicinal Chemistry 2022, 230, 114137. https://doi.org/10.1016/j.ejmech.2022.114137.. in European Journal of Medicinal Chemistry
Elsevier..
https://hdl.handle.net/21.15107/rcub_cherry_4878
Radaković N, Nikolić A, Terzić Jovanović N, Stojković P, Stanković N, Šolaja BA, Opsenica I, Pavić A. Supplementary data for article: Radakovic, N.; Nikolić, A.; Jovanović, N. T.; Stojković, P.; Stankovic, N.; Šolaja, B.; Opsenica, I.; Pavic, A. Unraveling the Anti-Virulence Potential and Antifungal Efficacy of 5-Aminotetrazoles Using the Zebrafish Model of Disseminated Candidiasis. European Journal of Medicinal Chemistry 2022, 230, 114137. https://doi.org/10.1016/j.ejmech.2022.114137.. in European Journal of Medicinal Chemistry. 2022;.
https://hdl.handle.net/21.15107/rcub_cherry_4878 .
Radaković, Nataša, Nikolić, Andrea, Terzić Jovanović, Nataša, Stojković, Pavle, Stanković, Nada, Šolaja, Bogdan A., Opsenica, Igor, Pavić, Aleksandar, "Supplementary data for article: Radakovic, N.; Nikolić, A.; Jovanović, N. T.; Stojković, P.; Stankovic, N.; Šolaja, B.; Opsenica, I.; Pavic, A. Unraveling the Anti-Virulence Potential and Antifungal Efficacy of 5-Aminotetrazoles Using the Zebrafish Model of Disseminated Candidiasis. European Journal of Medicinal Chemistry 2022, 230, 114137. https://doi.org/10.1016/j.ejmech.2022.114137." in European Journal of Medicinal Chemistry (2022),
https://hdl.handle.net/21.15107/rcub_cherry_4878 .

TiO2–CeO2 composite coatings for photocatalytic degradation of chloropesticide and organic dye

Radić, Nenad; Grbić, Boško; Stojadinović, Stevan; Ilić, Mila V.; Došen, Ognjen; Stefanov, Plamen

(Springer, 2022)

TY  - JOUR
AU  - Radić, Nenad
AU  - Grbić, Boško
AU  - Stojadinović, Stevan
AU  - Ilić, Mila V.
AU  - Došen, Ognjen
AU  - Stefanov, Plamen
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4881
AB  - Spray pyrolysis was used to deposit CeO2–TiO2 coatings on stainless steel substrates. The addition of CeO2 to TiO2 changes morphology of the coatings, causing the surface to become laced and some CeO2 ions are incorporated into TiO2 crystal lattice. Part of CeO2 is highly dispersed on the surface of TiO2. The XPS showed the simultaneous existence of Ce4+ and Ce3+ on coating surface. As the CeO2 content in composites increases from 0.5 to 20%, the band gap decreases from 3.16 to 2.88 eV, respectively. The photoactivities in the degradation of methyl orange and lindane were significantly influenced by the content of Ce in composite. For methyl orange photodegradation, the highest activity had coating with CeO2 content of 2 wt%. In contrast, the activity of coatings in lindane photodegradation gradually decreases as the CeO2 content increases. However, efficiency of CeO2–TiO2 coatings remained satisfactory for application in process of lindane degradation. Lindane conversion at 6 h of irradiation is in the range from 88% for pure TiO2 to 60% for CeO2–TiO2 coating with CeO2 content of 20 wt%. Photodegradation of lindane was enhanced on pure TiO2 sites, while methyl orange degradation is highest on composite CeO2/TiO2 species with CeO2 content of 2 wt%.
PB  - Springer
T2  - Journal of Materials Science: Materials in Electronics
T1  - TiO2–CeO2 composite coatings for photocatalytic degradation of chloropesticide and organic dye
VL  - n/a
DO  - 10.1007/s10854-022-07698-9
ER  - 
@article{
author = "Radić, Nenad and Grbić, Boško and Stojadinović, Stevan and Ilić, Mila V. and Došen, Ognjen and Stefanov, Plamen",
year = "2022",
abstract = "Spray pyrolysis was used to deposit CeO2–TiO2 coatings on stainless steel substrates. The addition of CeO2 to TiO2 changes morphology of the coatings, causing the surface to become laced and some CeO2 ions are incorporated into TiO2 crystal lattice. Part of CeO2 is highly dispersed on the surface of TiO2. The XPS showed the simultaneous existence of Ce4+ and Ce3+ on coating surface. As the CeO2 content in composites increases from 0.5 to 20%, the band gap decreases from 3.16 to 2.88 eV, respectively. The photoactivities in the degradation of methyl orange and lindane were significantly influenced by the content of Ce in composite. For methyl orange photodegradation, the highest activity had coating with CeO2 content of 2 wt%. In contrast, the activity of coatings in lindane photodegradation gradually decreases as the CeO2 content increases. However, efficiency of CeO2–TiO2 coatings remained satisfactory for application in process of lindane degradation. Lindane conversion at 6 h of irradiation is in the range from 88% for pure TiO2 to 60% for CeO2–TiO2 coating with CeO2 content of 20 wt%. Photodegradation of lindane was enhanced on pure TiO2 sites, while methyl orange degradation is highest on composite CeO2/TiO2 species with CeO2 content of 2 wt%.",
publisher = "Springer",
journal = "Journal of Materials Science: Materials in Electronics",
title = "TiO2–CeO2 composite coatings for photocatalytic degradation of chloropesticide and organic dye",
volume = "n/a",
doi = "10.1007/s10854-022-07698-9"
}
Radić, N., Grbić, B., Stojadinović, S., Ilić, M. V., Došen, O.,& Stefanov, P.. (2022). TiO2–CeO2 composite coatings for photocatalytic degradation of chloropesticide and organic dye. in Journal of Materials Science: Materials in Electronics
Springer., n/a.
https://doi.org/10.1007/s10854-022-07698-9
Radić N, Grbić B, Stojadinović S, Ilić MV, Došen O, Stefanov P. TiO2–CeO2 composite coatings for photocatalytic degradation of chloropesticide and organic dye. in Journal of Materials Science: Materials in Electronics. 2022;n/a.
doi:10.1007/s10854-022-07698-9 .
Radić, Nenad, Grbić, Boško, Stojadinović, Stevan, Ilić, Mila V., Došen, Ognjen, Stefanov, Plamen, "TiO2–CeO2 composite coatings for photocatalytic degradation of chloropesticide and organic dye" in Journal of Materials Science: Materials in Electronics, n/a (2022),
https://doi.org/10.1007/s10854-022-07698-9 . .

GC–MS-based metabolomics for the detection of adulteration in oregano samples

Ivanović, Stefan; Mandrone, Manuela; Simić, Katarina; Ristić, Mirjana; Todosijević, Marina; Mandić, Boris; Gođevac, Dejan

(Belgrade : Serbian Chemical Society, 2021)

TY  - JOUR
AU  - Ivanović, Stefan
AU  - Mandrone, Manuela
AU  - Simić, Katarina
AU  - Ristić, Mirjana
AU  - Todosijević, Marina
AU  - Mandić, Boris
AU  - Gođevac, Dejan
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5035
AB  - Oregano is one of the most used culinary herb and it is often adulterated with cheaper plants. In this study, GC–MS was used for identification
and quantification of metabolites from 104 samples of oregano (Origanum vulgare and O. onites) adulterated with olive (Olea europaea), venetian sumac
(Cotinus coggygria) and myrtle (Myrtus communis) leaves, at five different
concentration levels. The metabolomics profiles obtained after the two-step
derivatization, involving methoxyamination and silanization, were subjected to
multivariate data analysis to reveal markers of adulteration and to build the regression models on the basis of the oregano-to-adulterants mixing ratio. Orthogonal partial least squares enabled detection of oregano adulterations with
olive, Venetian sumac and myrtle leaves. Sorbitol levels distinguished oregano
samples adulterated with olive leaves, while shikimic and quinic acids were
recognized as discrimination factor for adulteration of oregano with venetian
sumac. Fructose and quinic acid levels correlated with oregano adulteration
with myrtle. Orthogonal partial least squares discriminant analysis enabled discrimination of O. vulgare and O. onites samples, where catechollactate was
found to be discriminating metabolite.
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - GC–MS-based metabolomics for the detection of adulteration in oregano samples
VL  - 86
IS  - 12
SP  - 1195
EP  - 1203
DO  - 10.2298/JSC210809089I
ER  - 
@article{
author = "Ivanović, Stefan and Mandrone, Manuela and Simić, Katarina and Ristić, Mirjana and Todosijević, Marina and Mandić, Boris and Gođevac, Dejan",
year = "2021",
abstract = "Oregano is one of the most used culinary herb and it is often adulterated with cheaper plants. In this study, GC–MS was used for identification
and quantification of metabolites from 104 samples of oregano (Origanum vulgare and O. onites) adulterated with olive (Olea europaea), venetian sumac
(Cotinus coggygria) and myrtle (Myrtus communis) leaves, at five different
concentration levels. The metabolomics profiles obtained after the two-step
derivatization, involving methoxyamination and silanization, were subjected to
multivariate data analysis to reveal markers of adulteration and to build the regression models on the basis of the oregano-to-adulterants mixing ratio. Orthogonal partial least squares enabled detection of oregano adulterations with
olive, Venetian sumac and myrtle leaves. Sorbitol levels distinguished oregano
samples adulterated with olive leaves, while shikimic and quinic acids were
recognized as discrimination factor for adulteration of oregano with venetian
sumac. Fructose and quinic acid levels correlated with oregano adulteration
with myrtle. Orthogonal partial least squares discriminant analysis enabled discrimination of O. vulgare and O. onites samples, where catechollactate was
found to be discriminating metabolite.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "GC–MS-based metabolomics for the detection of adulteration in oregano samples",
volume = "86",
number = "12",
pages = "1195-1203",
doi = "10.2298/JSC210809089I"
}
Ivanović, S., Mandrone, M., Simić, K., Ristić, M., Todosijević, M., Mandić, B.,& Gođevac, D.. (2021). GC–MS-based metabolomics for the detection of adulteration in oregano samples. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society., 86(12), 1195-1203.
https://doi.org/10.2298/JSC210809089I
Ivanović S, Mandrone M, Simić K, Ristić M, Todosijević M, Mandić B, Gođevac D. GC–MS-based metabolomics for the detection of adulteration in oregano samples. in Journal of the Serbian Chemical Society. 2021;86(12):1195-1203.
doi:10.2298/JSC210809089I .
Ivanović, Stefan, Mandrone, Manuela, Simić, Katarina, Ristić, Mirjana, Todosijević, Marina, Mandić, Boris, Gođevac, Dejan, "GC–MS-based metabolomics for the detection of adulteration in oregano samples" in Journal of the Serbian Chemical Society, 86, no. 12 (2021):1195-1203,
https://doi.org/10.2298/JSC210809089I . .

Supplementary data for the article: Ivanović, S.; Mandrone, M.; Simić, K.; Ristić, M.; Todosijević, M.; Mandić, B.; Gođevac, D. GC-MS-Based Metabolomics for the Detection of Adulteration in Oregano Samples. Journal of the Serbian Chemical Society 2021, 86 (12), 1195–1203. https://doi.org/10.2298/JSC210809089I.

Ivanović, Stefan; Mandrone, Manuela; Simić, Katarina; Ristić, Mirjana; Todosijević, Marina; Mandić, Boris; Gođevac, Dejan

(Belgrade : Serbian Chemical Society, 2021)

TY  - DATA
AU  - Ivanović, Stefan
AU  - Mandrone, Manuela
AU  - Simić, Katarina
AU  - Ristić, Mirjana
AU  - Todosijević, Marina
AU  - Mandić, Boris
AU  - Gođevac, Dejan
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5118
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Supplementary data for the article: Ivanović, S.; Mandrone, M.; Simić, K.; Ristić, M.; Todosijević, M.; Mandić, B.; Gođevac, D. GC-MS-Based Metabolomics for the Detection of Adulteration in Oregano Samples. Journal of the Serbian Chemical Society 2021, 86 (12), 1195–1203. https://doi.org/10.2298/JSC210809089I.
DO  - 10.2298/JSC210809089I
ER  - 
@misc{
author = "Ivanović, Stefan and Mandrone, Manuela and Simić, Katarina and Ristić, Mirjana and Todosijević, Marina and Mandić, Boris and Gođevac, Dejan",
year = "2021",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Supplementary data for the article: Ivanović, S.; Mandrone, M.; Simić, K.; Ristić, M.; Todosijević, M.; Mandić, B.; Gođevac, D. GC-MS-Based Metabolomics for the Detection of Adulteration in Oregano Samples. Journal of the Serbian Chemical Society 2021, 86 (12), 1195–1203. https://doi.org/10.2298/JSC210809089I.",
doi = "10.2298/JSC210809089I"
}
Ivanović, S., Mandrone, M., Simić, K., Ristić, M., Todosijević, M., Mandić, B.,& Gođevac, D.. (2021). Supplementary data for the article: Ivanović, S.; Mandrone, M.; Simić, K.; Ristić, M.; Todosijević, M.; Mandić, B.; Gođevac, D. GC-MS-Based Metabolomics for the Detection of Adulteration in Oregano Samples. Journal of the Serbian Chemical Society 2021, 86 (12), 1195–1203. https://doi.org/10.2298/JSC210809089I.. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society..
https://doi.org/10.2298/JSC210809089I
Ivanović S, Mandrone M, Simić K, Ristić M, Todosijević M, Mandić B, Gođevac D. Supplementary data for the article: Ivanović, S.; Mandrone, M.; Simić, K.; Ristić, M.; Todosijević, M.; Mandić, B.; Gođevac, D. GC-MS-Based Metabolomics for the Detection of Adulteration in Oregano Samples. Journal of the Serbian Chemical Society 2021, 86 (12), 1195–1203. https://doi.org/10.2298/JSC210809089I.. in Journal of the Serbian Chemical Society. 2021;.
doi:10.2298/JSC210809089I .
Ivanović, Stefan, Mandrone, Manuela, Simić, Katarina, Ristić, Mirjana, Todosijević, Marina, Mandić, Boris, Gođevac, Dejan, "Supplementary data for the article: Ivanović, S.; Mandrone, M.; Simić, K.; Ristić, M.; Todosijević, M.; Mandić, B.; Gođevac, D. GC-MS-Based Metabolomics for the Detection of Adulteration in Oregano Samples. Journal of the Serbian Chemical Society 2021, 86 (12), 1195–1203. https://doi.org/10.2298/JSC210809089I." in Journal of the Serbian Chemical Society (2021),
https://doi.org/10.2298/JSC210809089I . .

Phytochemical investigation of Pimpinella serbica

Vučković, Ivan; Stiković, Sonja; Stešević, Danijela; Jadranin, Milka; Trifunović, Snežana

(Belgrade : Serbian Chemical Society, 2021)

TY  - JOUR
AU  - Vučković, Ivan
AU  - Stiković, Sonja
AU  - Stešević, Danijela
AU  - Jadranin, Milka
AU  - Trifunović, Snežana
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5040
AB  - The plant species Pimpinella serbica (Vis.) Drude, endemic to West
Balkans, belongs to the genus Pimpinella L. (Apiaceae) according to newer
botanical classification. Initially, the plant was described as Pancicia serbica Vis.
and long considered as a monotypic genus. Previous phytochemical investigations
of this plant were limited to the essential oil analysis by the GC–MS method. This
is first study that includes LC-DAD–MS screening of the extracts of the roots and
aerial parts, followed by isolation of secondary metabolites using chromatographic
techniques. Five compounds belonging to phenylpropanoids and polyacetylenes,
well known for their bioactivities, were isolated and structurally determined by
combined spectroscopic methods (UV, NMR, MS). Dillapiole (1), nothoapiole (2)
and oplopantriol A 18-acetate (4) were found in both extracts, while falcarindiol (3)
was isolated from the roots and dendrotrifidol (5) from the aerial parts only. The
phytochemical profile of P. serbica L. supports its position in the Pimpinella L.
genus.
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Phytochemical investigation of Pimpinella serbica
VL  - 86
IS  - 12
SP  - 1241
EP  - 1247
DO  - 10.2298/JSC210816081V
ER  - 
@article{
author = "Vučković, Ivan and Stiković, Sonja and Stešević, Danijela and Jadranin, Milka and Trifunović, Snežana",
year = "2021",
abstract = "The plant species Pimpinella serbica (Vis.) Drude, endemic to West
Balkans, belongs to the genus Pimpinella L. (Apiaceae) according to newer
botanical classification. Initially, the plant was described as Pancicia serbica Vis.
and long considered as a monotypic genus. Previous phytochemical investigations
of this plant were limited to the essential oil analysis by the GC–MS method. This
is first study that includes LC-DAD–MS screening of the extracts of the roots and
aerial parts, followed by isolation of secondary metabolites using chromatographic
techniques. Five compounds belonging to phenylpropanoids and polyacetylenes,
well known for their bioactivities, were isolated and structurally determined by
combined spectroscopic methods (UV, NMR, MS). Dillapiole (1), nothoapiole (2)
and oplopantriol A 18-acetate (4) were found in both extracts, while falcarindiol (3)
was isolated from the roots and dendrotrifidol (5) from the aerial parts only. The
phytochemical profile of P. serbica L. supports its position in the Pimpinella L.
genus.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Phytochemical investigation of Pimpinella serbica",
volume = "86",
number = "12",
pages = "1241-1247",
doi = "10.2298/JSC210816081V"
}
Vučković, I., Stiković, S., Stešević, D., Jadranin, M.,& Trifunović, S.. (2021). Phytochemical investigation of Pimpinella serbica. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society., 86(12), 1241-1247.
https://doi.org/10.2298/JSC210816081V
Vučković I, Stiković S, Stešević D, Jadranin M, Trifunović S. Phytochemical investigation of Pimpinella serbica. in Journal of the Serbian Chemical Society. 2021;86(12):1241-1247.
doi:10.2298/JSC210816081V .
Vučković, Ivan, Stiković, Sonja, Stešević, Danijela, Jadranin, Milka, Trifunović, Snežana, "Phytochemical investigation of Pimpinella serbica" in Journal of the Serbian Chemical Society, 86, no. 12 (2021):1241-1247,
https://doi.org/10.2298/JSC210816081V . .

Supplementary data for the article: Vučković, I.; Stiković, S.; Stešević, D.; Jadranin, M.; Trifunović, S. Phytochemical Investigation of Pimpinella Serbica. Journal of the Serbian Chemical Society 2021, 86 (12), 1241–1247. https://doi.org/10.2298/JSC210816081V.

Vučković, Ivan; Stiković, Sonja; Stešević, Danijela; Jadranin, Milka; Trifunović, Snežana

(Belgrade : Serbian Chemical Society, 2021)

TY  - DATA
AU  - Vučković, Ivan
AU  - Stiković, Sonja
AU  - Stešević, Danijela
AU  - Jadranin, Milka
AU  - Trifunović, Snežana
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5117
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Supplementary data for the article: Vučković, I.; Stiković, S.; Stešević, D.; Jadranin, M.; Trifunović, S. Phytochemical Investigation of Pimpinella Serbica. Journal of the Serbian Chemical Society 2021, 86 (12), 1241–1247. https://doi.org/10.2298/JSC210816081V.
ER  - 
@misc{
author = "Vučković, Ivan and Stiković, Sonja and Stešević, Danijela and Jadranin, Milka and Trifunović, Snežana",
year = "2021",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Supplementary data for the article: Vučković, I.; Stiković, S.; Stešević, D.; Jadranin, M.; Trifunović, S. Phytochemical Investigation of Pimpinella Serbica. Journal of the Serbian Chemical Society 2021, 86 (12), 1241–1247. https://doi.org/10.2298/JSC210816081V."
}
Vučković, I., Stiković, S., Stešević, D., Jadranin, M.,& Trifunović, S.. (2021). Supplementary data for the article: Vučković, I.; Stiković, S.; Stešević, D.; Jadranin, M.; Trifunović, S. Phytochemical Investigation of Pimpinella Serbica. Journal of the Serbian Chemical Society 2021, 86 (12), 1241–1247. https://doi.org/10.2298/JSC210816081V.. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society..
Vučković I, Stiković S, Stešević D, Jadranin M, Trifunović S. Supplementary data for the article: Vučković, I.; Stiković, S.; Stešević, D.; Jadranin, M.; Trifunović, S. Phytochemical Investigation of Pimpinella Serbica. Journal of the Serbian Chemical Society 2021, 86 (12), 1241–1247. https://doi.org/10.2298/JSC210816081V.. in Journal of the Serbian Chemical Society. 2021;..
Vučković, Ivan, Stiković, Sonja, Stešević, Danijela, Jadranin, Milka, Trifunović, Snežana, "Supplementary data for the article: Vučković, I.; Stiković, S.; Stešević, D.; Jadranin, M.; Trifunović, S. Phytochemical Investigation of Pimpinella Serbica. Journal of the Serbian Chemical Society 2021, 86 (12), 1241–1247. https://doi.org/10.2298/JSC210816081V." in Journal of the Serbian Chemical Society (2021).

Carboxylated single-wall carbon nanotubes decorated with SiO2 coated-Nd2O3 nanoparticles as an electrochemical sensor for L-DOPA detection

Đurđić, Slađana; Stanković, Vesna; Vlahović, Filip; Ognjanović, Miloš; Kalcher, Kurt; Manojlović, Dragan D.; Mutić, Jelena; Stanković, Dalibor

(2021)

TY  - JOUR
AU  - Đurđić, Slađana
AU  - Stanković, Vesna
AU  - Vlahović, Filip
AU  - Ognjanović, Miloš
AU  - Kalcher, Kurt
AU  - Manojlović, Dragan D.
AU  - Mutić, Jelena
AU  - Stanković, Dalibor
PY  - 2021
UR  - https://www.sciencedirect.com/science/article/pii/S0026265X21005002
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4543
AB  - L-DOPA (L-3,4-dihydroxyphenylalanine), the precursor of dopamine, is widely used in the treatment of Parkinson’s disease, thus determining and monitoring the concentration of L-DOPA is of utmost importance for both medical and scientific purposes. Although many analytical approaches, designed for drug detection and quantification, already exist, there is a constant need for modification of old and tailoring of new, faster, and selective methods. Redox active chemical species, such as L-DOPA, can be measured directly by electrochemical means, whereas electrochemical sensors combine sensitivity and selectivity within a small analytical device. This work demonstrates the development of such electrochemical sensor, based on carboxylated single-wall carbon nanotubes (SWCNT-COOH) decorated with SiO2 coated-Nd2O3 nanoparticles, and further application for the detection of L-DOPA. Developed SWCNT-COOH@Nd2O3-SiO2 sensor shows linear response in the range from 2 µmol L−1 to 52 µmol L−1 analyte concentration, and beside the low detection limit, it is characterized by a fast response time, as well as good life-time, reproducibility and repeatability.
T2  - Microchemical Journal
T1  - Carboxylated single-wall carbon nanotubes decorated with SiO2 coated-Nd2O3 nanoparticles as an electrochemical sensor for L-DOPA detection
VL  - 168
SP  - 106416
DO  - 10.1016/j.microc.2021.106416
ER  - 
@article{
author = "Đurđić, Slađana and Stanković, Vesna and Vlahović, Filip and Ognjanović, Miloš and Kalcher, Kurt and Manojlović, Dragan D. and Mutić, Jelena and Stanković, Dalibor",
year = "2021",
abstract = "L-DOPA (L-3,4-dihydroxyphenylalanine), the precursor of dopamine, is widely used in the treatment of Parkinson’s disease, thus determining and monitoring the concentration of L-DOPA is of utmost importance for both medical and scientific purposes. Although many analytical approaches, designed for drug detection and quantification, already exist, there is a constant need for modification of old and tailoring of new, faster, and selective methods. Redox active chemical species, such as L-DOPA, can be measured directly by electrochemical means, whereas electrochemical sensors combine sensitivity and selectivity within a small analytical device. This work demonstrates the development of such electrochemical sensor, based on carboxylated single-wall carbon nanotubes (SWCNT-COOH) decorated with SiO2 coated-Nd2O3 nanoparticles, and further application for the detection of L-DOPA. Developed SWCNT-COOH@Nd2O3-SiO2 sensor shows linear response in the range from 2 µmol L−1 to 52 µmol L−1 analyte concentration, and beside the low detection limit, it is characterized by a fast response time, as well as good life-time, reproducibility and repeatability.",
journal = "Microchemical Journal",
title = "Carboxylated single-wall carbon nanotubes decorated with SiO2 coated-Nd2O3 nanoparticles as an electrochemical sensor for L-DOPA detection",
volume = "168",
pages = "106416",
doi = "10.1016/j.microc.2021.106416"
}
Đurđić, S., Stanković, V., Vlahović, F., Ognjanović, M., Kalcher, K., Manojlović, D. D., Mutić, J.,& Stanković, D.. (2021). Carboxylated single-wall carbon nanotubes decorated with SiO2 coated-Nd2O3 nanoparticles as an electrochemical sensor for L-DOPA detection. in Microchemical Journal, 168, 106416.
https://doi.org/10.1016/j.microc.2021.106416
Đurđić S, Stanković V, Vlahović F, Ognjanović M, Kalcher K, Manojlović DD, Mutić J, Stanković D. Carboxylated single-wall carbon nanotubes decorated with SiO2 coated-Nd2O3 nanoparticles as an electrochemical sensor for L-DOPA detection. in Microchemical Journal. 2021;168:106416.
doi:10.1016/j.microc.2021.106416 .
Đurđić, Slađana, Stanković, Vesna, Vlahović, Filip, Ognjanović, Miloš, Kalcher, Kurt, Manojlović, Dragan D., Mutić, Jelena, Stanković, Dalibor, "Carboxylated single-wall carbon nanotubes decorated with SiO2 coated-Nd2O3 nanoparticles as an electrochemical sensor for L-DOPA detection" in Microchemical Journal, 168 (2021):106416,
https://doi.org/10.1016/j.microc.2021.106416 . .
3
3

Supplementary data for the article: Đurđić, S.; Stanković, V.; Vlahović, F.; Ognjanović, M.; Kalcher, K.; Manojlović, D.; Mutić, J.; Stanković, D. M. Carboxylated Single-Wall Carbon Nanotubes Decorated with SiO2 Coated-Nd2O3 Nanoparticles as an Electrochemical Sensor for L-DOPA Detection. Microchemical Journal 2021, 168, 106416. https://doi.org/10.1016/j.microc.2021.106416.

Đurđić, Slađana; Stanković, Vesna; Vlahović, Filip; Ognjanović, Miloš; Kalcher, Kurt; Manojlović, Dragan D.; Mutić, Jelena; Stanković, Dalibor

(2021)

TY  - DATA
AU  - Đurđić, Slađana
AU  - Stanković, Vesna
AU  - Vlahović, Filip
AU  - Ognjanović, Miloš
AU  - Kalcher, Kurt
AU  - Manojlović, Dragan D.
AU  - Mutić, Jelena
AU  - Stanković, Dalibor
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4544
T2  - Microchemical Journal
T1  - Supplementary data for the article: Đurđić, S.; Stanković, V.; Vlahović, F.; Ognjanović, M.; Kalcher, K.; Manojlović, D.; Mutić, J.; Stanković, D. M. Carboxylated Single-Wall Carbon Nanotubes Decorated with SiO2 Coated-Nd2O3 Nanoparticles as an Electrochemical Sensor for L-DOPA Detection. Microchemical Journal 2021, 168, 106416. https://doi.org/10.1016/j.microc.2021.106416.
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4544
ER  - 
@misc{
author = "Đurđić, Slađana and Stanković, Vesna and Vlahović, Filip and Ognjanović, Miloš and Kalcher, Kurt and Manojlović, Dragan D. and Mutić, Jelena and Stanković, Dalibor",
year = "2021",
journal = "Microchemical Journal",
title = "Supplementary data for the article: Đurđić, S.; Stanković, V.; Vlahović, F.; Ognjanović, M.; Kalcher, K.; Manojlović, D.; Mutić, J.; Stanković, D. M. Carboxylated Single-Wall Carbon Nanotubes Decorated with SiO2 Coated-Nd2O3 Nanoparticles as an Electrochemical Sensor for L-DOPA Detection. Microchemical Journal 2021, 168, 106416. https://doi.org/10.1016/j.microc.2021.106416.",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4544"
}
Đurđić, S., Stanković, V., Vlahović, F., Ognjanović, M., Kalcher, K., Manojlović, D. D., Mutić, J.,& Stanković, D.. (2021). Supplementary data for the article: Đurđić, S.; Stanković, V.; Vlahović, F.; Ognjanović, M.; Kalcher, K.; Manojlović, D.; Mutić, J.; Stanković, D. M. Carboxylated Single-Wall Carbon Nanotubes Decorated with SiO2 Coated-Nd2O3 Nanoparticles as an Electrochemical Sensor for L-DOPA Detection. Microchemical Journal 2021, 168, 106416. https://doi.org/10.1016/j.microc.2021.106416.. in Microchemical Journal.
https://hdl.handle.net/21.15107/rcub_cherry_4544
Đurđić S, Stanković V, Vlahović F, Ognjanović M, Kalcher K, Manojlović DD, Mutić J, Stanković D. Supplementary data for the article: Đurđić, S.; Stanković, V.; Vlahović, F.; Ognjanović, M.; Kalcher, K.; Manojlović, D.; Mutić, J.; Stanković, D. M. Carboxylated Single-Wall Carbon Nanotubes Decorated with SiO2 Coated-Nd2O3 Nanoparticles as an Electrochemical Sensor for L-DOPA Detection. Microchemical Journal 2021, 168, 106416. https://doi.org/10.1016/j.microc.2021.106416.. in Microchemical Journal. 2021;.
https://hdl.handle.net/21.15107/rcub_cherry_4544 .
Đurđić, Slađana, Stanković, Vesna, Vlahović, Filip, Ognjanović, Miloš, Kalcher, Kurt, Manojlović, Dragan D., Mutić, Jelena, Stanković, Dalibor, "Supplementary data for the article: Đurđić, S.; Stanković, V.; Vlahović, F.; Ognjanović, M.; Kalcher, K.; Manojlović, D.; Mutić, J.; Stanković, D. M. Carboxylated Single-Wall Carbon Nanotubes Decorated with SiO2 Coated-Nd2O3 Nanoparticles as an Electrochemical Sensor for L-DOPA Detection. Microchemical Journal 2021, 168, 106416. https://doi.org/10.1016/j.microc.2021.106416." in Microchemical Journal (2021),
https://hdl.handle.net/21.15107/rcub_cherry_4544 .

GC/MS and TOC Analyses of Ibuprofen after Degradation in Waterusing Chlorine Dioxide

Pergal, M. V.; Kodranov, Igor; Pergal, M. M.; Manojlović, Dragan D.

(Belgrade : Serbian Chemical Society, 2021)

TY  - CONF
AU  - Pergal, M. V.
AU  - Kodranov, Igor
AU  - Pergal, M. M.
AU  - Manojlović, Dragan D.
PY  - 2021
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4919
AB  - Drinking water and wastewater treatment facilities often have a chemical oxidationstep for disinfection, the removal of organic micropollutants, color removal and taste andodor control. Among the most commonly used oxidants are chlorine dioxide (ClO2 ), chlorine, and ozone.ClO2  has been increasinglyemployed as disinfectant in water treatment due to its antibacterial and antiviral properties. As a powerful oxidant, ClO2  can remove many organic and inorganic pollutants [1,2]. The aim of the present study was to assess thepotential of ClO2  to oxidize pharmaceutical during water treatment. Therefore, degradation of ibuprofen (IBP) using ClO2 in water was investigated.The degradation under different reaction conditions (concentration of ClO2 : 5, 10, 15 mg/L; concentration of ibuprofen: 10, 20, 35, 60 mg/L; reaction time: from 0.5 to 24 h; pH values: 3, 7, 10) was monitored using high performance liquid chromatography (HPLC) analysis, while mineralization degree was detemined by total organic carbon (TOC) measurements. The highest degree of IBPdegradation in deionized water was obtained by treatment with 15 mg/L ClO2 , using 10 mg/L ibuprofen, at pH = 10, after 24 h of treatment. The obtained degradation degree value under optimal conditions was 99%. TOC analysis of ibuprofen showed reduction in content of organic carbon in the solution. Before degradation TOC content was 7.8 mg/L and after 5.6 mg/L. This showes that degradation and mineralization of ibuprofen occur during this process. The degradation products obtained under optimal conditions were analyzed and confirmed by gas chromatography–mass spectra (GC–MS) and the reaction pathwayswere proposed.From GC chromatograms, degradation products of ibuprofen appeared at following retention times: 4.35 min, 5.12 min, 6.76 min, and 7.05 min. After the analysis of mass spectra, based on the spectral characteristics and the ratio of mass and charge (m/z), it was determined that there are four main degradation products of ibuprofen, after treatment with ClO2.The first characteristic ion appeared at 6.76 min and has m/z 163 (2-(4-methylphenyl) propionic acid). In further degradation path, two products are formed, one of which is a characteristic ion with m/z 57 (2-methylpropane) at 4.36 min, while the other product is further decomposed to give two new products, one of which is also a characteristic ion with m/z 57 (acetic acid) at 5.21 min. Another characteristic ion having m/z 161 (1-ethyl-4-isobutylbenzene) appeared at 7.05 min. ClO2 treatment is an efficient method for IBP degradation.The findings of the present study are very useful for the treatment of drinking waters contaminated with pharmaceutical.
PB  - Belgrade : Serbian Chemical Society
C3  - Book of Abstracts 21st; European Meeting on Environmental Chemistry
T1  - GC/MS and TOC Analyses of Ibuprofen after Degradation in Waterusing Chlorine Dioxide
SP  - 128
EP  - 128
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4919
ER  - 
@conference{
author = "Pergal, M. V. and Kodranov, Igor and Pergal, M. M. and Manojlović, Dragan D.",
year = "2021",
abstract = "Drinking water and wastewater treatment facilities often have a chemical oxidationstep for disinfection, the removal of organic micropollutants, color removal and taste andodor control. Among the most commonly used oxidants are chlorine dioxide (ClO2 ), chlorine, and ozone.ClO2  has been increasinglyemployed as disinfectant in water treatment due to its antibacterial and antiviral properties. As a powerful oxidant, ClO2  can remove many organic and inorganic pollutants [1,2]. The aim of the present study was to assess thepotential of ClO2  to oxidize pharmaceutical during water treatment. Therefore, degradation of ibuprofen (IBP) using ClO2 in water was investigated.The degradation under different reaction conditions (concentration of ClO2 : 5, 10, 15 mg/L; concentration of ibuprofen: 10, 20, 35, 60 mg/L; reaction time: from 0.5 to 24 h; pH values: 3, 7, 10) was monitored using high performance liquid chromatography (HPLC) analysis, while mineralization degree was detemined by total organic carbon (TOC) measurements. The highest degree of IBPdegradation in deionized water was obtained by treatment with 15 mg/L ClO2 , using 10 mg/L ibuprofen, at pH = 10, after 24 h of treatment. The obtained degradation degree value under optimal conditions was 99%. TOC analysis of ibuprofen showed reduction in content of organic carbon in the solution. Before degradation TOC content was 7.8 mg/L and after 5.6 mg/L. This showes that degradation and mineralization of ibuprofen occur during this process. The degradation products obtained under optimal conditions were analyzed and confirmed by gas chromatography–mass spectra (GC–MS) and the reaction pathwayswere proposed.From GC chromatograms, degradation products of ibuprofen appeared at following retention times: 4.35 min, 5.12 min, 6.76 min, and 7.05 min. After the analysis of mass spectra, based on the spectral characteristics and the ratio of mass and charge (m/z), it was determined that there are four main degradation products of ibuprofen, after treatment with ClO2.The first characteristic ion appeared at 6.76 min and has m/z 163 (2-(4-methylphenyl) propionic acid). In further degradation path, two products are formed, one of which is a characteristic ion with m/z 57 (2-methylpropane) at 4.36 min, while the other product is further decomposed to give two new products, one of which is also a characteristic ion with m/z 57 (acetic acid) at 5.21 min. Another characteristic ion having m/z 161 (1-ethyl-4-isobutylbenzene) appeared at 7.05 min. ClO2 treatment is an efficient method for IBP degradation.The findings of the present study are very useful for the treatment of drinking waters contaminated with pharmaceutical.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Book of Abstracts 21st; European Meeting on Environmental Chemistry",
title = "GC/MS and TOC Analyses of Ibuprofen after Degradation in Waterusing Chlorine Dioxide",
pages = "128-128",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4919"
}
Pergal, M. V., Kodranov, I., Pergal, M. M.,& Manojlović, D. D.. (2021). GC/MS and TOC Analyses of Ibuprofen after Degradation in Waterusing Chlorine Dioxide. in Book of Abstracts 21st; European Meeting on Environmental Chemistry
Belgrade : Serbian Chemical Society., 128-128.
https://hdl.handle.net/21.15107/rcub_cherry_4919
Pergal MV, Kodranov I, Pergal MM, Manojlović DD. GC/MS and TOC Analyses of Ibuprofen after Degradation in Waterusing Chlorine Dioxide. in Book of Abstracts 21st; European Meeting on Environmental Chemistry. 2021;:128-128.
https://hdl.handle.net/21.15107/rcub_cherry_4919 .
Pergal, M. V., Kodranov, Igor, Pergal, M. M., Manojlović, Dragan D., "GC/MS and TOC Analyses of Ibuprofen after Degradation in Waterusing Chlorine Dioxide" in Book of Abstracts 21st; European Meeting on Environmental Chemistry (2021):128-128,
https://hdl.handle.net/21.15107/rcub_cherry_4919 .