TY  - JOUR
AU  - Milosavljević, Saša
AU  - Jadranin, Milka
AU  - Mladenović, Mića
AU  - Tešević, Vele
AU  - Menković, Nebojša
AU  - Mutavdžić, Dragosav
AU  - Krstić, Gordana B.
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4624
AB  - The aim of this research was to verify the authenticity of monofloral honeys from the territory of the Republic of Serbia on the basis of physicochemical parameters routinely measured in honey quality control using multivariate analysis. Seventeen samples of monofloral honey (11 samples of acacia honey and 6 samples of sunflower honey) from the territory of the Republic of Serbia were analyzed. Physicochemical analysis of the samples included the examination of basic quality parameters and qualitative and quantitative analyses of phenolic compounds. In the samples tested, a total of 93 phenolic compounds were tentatively identified, and 19 of them were quantified. The obtained physicochemical analysis of the data served as input for the multivariate analysis. The hеаt map, which is useful for visualizing numerical data, was used for this purpose. The obtained results showed that the applied data can serve to clearly separate acacia and sunflower honeys.
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Physicochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia
VL  - 40
IS  - 1
SP  - 57
EP  - 67
DO  - 10.20450/mjcce.2021.2186
ER  - 

@article{
author = "Milosavljević, Saša and Jadranin, Milka and Mladenović, Mića and Tešević, Vele and Menković, Nebojša and Mutavdžić, Dragosav and Krstić, Gordana B.",
year = "2021",
abstract = "The aim of this research was to verify the authenticity of monofloral honeys from the territory of the Republic of Serbia on the basis of physicochemical parameters routinely measured in honey quality control using multivariate analysis. Seventeen samples of monofloral honey (11 samples of acacia honey and 6 samples of sunflower honey) from the territory of the Republic of Serbia were analyzed. Physicochemical analysis of the samples included the examination of basic quality parameters and qualitative and quantitative analyses of phenolic compounds. In the samples tested, a total of 93 phenolic compounds were tentatively identified, and 19 of them were quantified. The obtained physicochemical analysis of the data served as input for the multivariate analysis. The hеаt map, which is useful for visualizing numerical data, was used for this purpose. The obtained results showed that the applied data can serve to clearly separate acacia and sunflower honeys.",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Physicochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia",
volume = "40",
number = "1",
pages = "57-67",
doi = "10.20450/mjcce.2021.2186"
}

Milosavljević, S., Jadranin, M., Mladenović, M., Tešević, V., Menković, N., Mutavdžić, D.,& Krstić, G. B.. (2021). Physicochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia. in Macedonian Journal of Chemistry and Chemical Engineering, 40(1), 57-67.
https://doi.org/10.20450/mjcce.2021.2186

Milosavljević S, Jadranin M, Mladenović M, Tešević V, Menković N, Mutavdžić D, Krstić GB. Physicochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia. in Macedonian Journal of Chemistry and Chemical Engineering. 2021;40(1):57-67.
doi:10.20450/mjcce.2021.2186 .

Milosavljević, Saša, Jadranin, Milka, Mladenović, Mića, Tešević, Vele, Menković, Nebojša, Mutavdžić, Dragosav, Krstić, Gordana B., "Physicochemical parameters as indicators of the authenticity of monofloral honey from the territory of the Republic of Serbia" in Macedonian Journal of Chemistry and Chemical Engineering, 40, no. 1 (2021):57-67,
https://doi.org/10.20450/mjcce.2021.2186 . .

TY  - JOUR
AU  - Karaman, Maja
AU  - Tesanovic, Kristina
AU  - Gorjanovic, Stanislava
AU  - Pastor, Ferenc
AU  - Simonovic, Mladen
AU  - Glumac, Miodrag
AU  - Pejin, Boris
PY  - 2021
UR  - http://www.ncbi.nlm.nih.gov/pubmed/31192702
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4773
AB  - This study was focused on in vitro screening of the total antioxidant activity of the selected extracts of the mushroom Coprinus comatus and quinic acid, one of their antidiabetic ingredients, by an uncommon electrochemical assay. Indeed, direct current (DC) polarographic HydroxoPerhydroxo Mercury(II) Complex (HPMC) assay based on decrease of anodic limiting current originating from HPMC formation in alkaline solutions of hydrogen peroxide at potential of mercury dissolution, observed upon gradual addition of antioxidants, was applied herein for the estimation of the natural products' antioxidativity. Quinic acid was found to exhibit most promising antioxidant potential (4.0 ± 0.2%µL-1) being ≈ 2-fold more active than the screened C. comatus extract samples. Actually, such a finding puts some light on the antioxidativity of cyclic polyols, well understimated class of organic compounds, compared to aromatic (poly)phenolics. As a low cost, easy-to handle and accurate this polarographic assay may be thoroughly recommended for much broader use. [Formula: see text].
T2  - Natural Product Research
T1  - Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient
VL  - 35
IS  - 10
SP  - 1711
EP  - 1716
DO  - 10.1080/14786419.2019.1628753
ER  - 

@article{
author = "Karaman, Maja and Tesanovic, Kristina and Gorjanovic, Stanislava and Pastor, Ferenc and Simonovic, Mladen and Glumac, Miodrag and Pejin, Boris",
year = "2021",
abstract = "This study was focused on in vitro screening of the total antioxidant activity of the selected extracts of the mushroom Coprinus comatus and quinic acid, one of their antidiabetic ingredients, by an uncommon electrochemical assay. Indeed, direct current (DC) polarographic HydroxoPerhydroxo Mercury(II) Complex (HPMC) assay based on decrease of anodic limiting current originating from HPMC formation in alkaline solutions of hydrogen peroxide at potential of mercury dissolution, observed upon gradual addition of antioxidants, was applied herein for the estimation of the natural products' antioxidativity. Quinic acid was found to exhibit most promising antioxidant potential (4.0 ± 0.2%µL-1) being ≈ 2-fold more active than the screened C. comatus extract samples. Actually, such a finding puts some light on the antioxidativity of cyclic polyols, well understimated class of organic compounds, compared to aromatic (poly)phenolics. As a low cost, easy-to handle and accurate this polarographic assay may be thoroughly recommended for much broader use. [Formula: see text].",
journal = "Natural Product Research",
title = "Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient",
volume = "35",
number = "10",
pages = "1711-1716",
doi = "10.1080/14786419.2019.1628753"
}

Karaman, M., Tesanovic, K., Gorjanovic, S., Pastor, F., Simonovic, M., Glumac, M.,& Pejin, B.. (2021). Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient. in Natural Product Research, 35(10), 1711-1716.
https://doi.org/10.1080/14786419.2019.1628753

Karaman M, Tesanovic K, Gorjanovic S, Pastor F, Simonovic M, Glumac M, Pejin B. Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient. in Natural Product Research. 2021;35(10):1711-1716.
doi:10.1080/14786419.2019.1628753 .

Karaman, Maja, Tesanovic, Kristina, Gorjanovic, Stanislava, Pastor, Ferenc, Simonovic, Mladen, Glumac, Miodrag, Pejin, Boris, "Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient" in Natural Product Research, 35, no. 10 (2021):1711-1716,
https://doi.org/10.1080/14786419.2019.1628753 . .

TY  - JOUR
AU  - Vesović, Nikola
AU  - Ćurčić, Srećko
AU  - Todosijević, Marina
AU  - Nenadić, Marija
AU  - Zhang, Wang
AU  - Vujisić, Ljubodrag V.
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3972
AB  - It is a commonly known fact that all ground beetles possess abdominal pygidial glands with relatively similar gross structure and function among species. Still, morphology of the glands and composition of their secretions have not been studied in most ground beetle species. These exocrine glands and their products are mainly associated with defence in natural environments. In this paper, we studied three predatory ground beetle species of the genus Carabus Linnaeus, 1758, namely C. (Archicarabus) montivagus Palliardi, 1825, C. (Megodontus) caelatus Fabricius, 1801, and C. (M.) violaceus Linnaeus, 1758, to identify chemical components of their pygidial gland secretions. Altogether, 10 carboxylic acids were isolated from the analysed secretions [two from the secretion of C. (A.) montivagus, 10 from that of C. (M.) caelatus, and nine from that of C. (M.) violaceus]. The finding of 2-hexenoic acid in the secretion of C. (M.) caelatus is the first finding of it within the entire subfamily Carabinae. In addition, we also analysed the morphology of glands of the species C. (M.) violaceus.
PB  - Springer
T2  - Chemoecology
T1  - Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species
VL  - 30
IS  - 2
SP  - 59
EP  - 68
DO  - 10.1007/s00049-019-00298-w
ER  - 

@article{
author = "Vesović, Nikola and Ćurčić, Srećko and Todosijević, Marina and Nenadić, Marija and Zhang, Wang and Vujisić, Ljubodrag V.",
year = "2020",
abstract = "It is a commonly known fact that all ground beetles possess abdominal pygidial glands with relatively similar gross structure and function among species. Still, morphology of the glands and composition of their secretions have not been studied in most ground beetle species. These exocrine glands and their products are mainly associated with defence in natural environments. In this paper, we studied three predatory ground beetle species of the genus Carabus Linnaeus, 1758, namely C. (Archicarabus) montivagus Palliardi, 1825, C. (Megodontus) caelatus Fabricius, 1801, and C. (M.) violaceus Linnaeus, 1758, to identify chemical components of their pygidial gland secretions. Altogether, 10 carboxylic acids were isolated from the analysed secretions [two from the secretion of C. (A.) montivagus, 10 from that of C. (M.) caelatus, and nine from that of C. (M.) violaceus]. The finding of 2-hexenoic acid in the secretion of C. (M.) caelatus is the first finding of it within the entire subfamily Carabinae. In addition, we also analysed the morphology of glands of the species C. (M.) violaceus.",
publisher = "Springer",
journal = "Chemoecology",
title = "Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species",
volume = "30",
number = "2",
pages = "59-68",
doi = "10.1007/s00049-019-00298-w"
}

Vesović, N., Ćurčić, S., Todosijević, M., Nenadić, M., Zhang, W.,& Vujisić, L. V.. (2020). Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species. in Chemoecology
Springer., 30(2), 59-68.
https://doi.org/10.1007/s00049-019-00298-w

Vesović N, Ćurčić S, Todosijević M, Nenadić M, Zhang W, Vujisić LV. Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species. in Chemoecology. 2020;30(2):59-68.
doi:10.1007/s00049-019-00298-w .

Vesović, Nikola, Ćurčić, Srećko, Todosijević, Marina, Nenadić, Marija, Zhang, Wang, Vujisić, Ljubodrag V., "Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species" in Chemoecology, 30, no. 2 (2020):59-68,
https://doi.org/10.1007/s00049-019-00298-w . .

TY  - JOUR
AU  - Vranić, Sofija
AU  - Ćurčić, Srećko
AU  - Vesović, Nikola
AU  - Mandić, Boris
AU  - Pantelić, Dejan
AU  - Vasović, Marija
AU  - Lazović, Vladimir
AU  - Zhang, Wang
AU  - Vujisić, Ljubodrag V.
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4240
AB  - Morphology of the pygidial glands and chemical composition of their secretions in adults of four ground beetle representatives of the Pterostichini tribe (Coleoptera: Carabidae) were analysed. Molops (Stenochoromus) montenegrinus, Pterostichus (Cophosus) cylindricus, P. (Feronidius) melas and P. (Pseudomaseus) nigrita were chemically tested, while the latter three species were morphologically investigated. Pterostichus (C.) cylindricus, P. (P.) nigrita and M. (S.) montenegrinus were chemically studied for the first time. Altogether, 23 chemical compounds were isolated using gas chromatography-mass spectrometry (GC-MS), of which some are new for Pterostichini or even Carabidae. Methacrylic acid was present in all species analysed. It was predominant in the secretion extract of P. (C.) cylindricus and P. (F.) melas. Isobutyric and 2-methylbutyric acids were the major components in the secretion of M. (S.) montenegrinus. Undecane, methacrylic and tiglic acids were the main components in the secretion of P. (P.) nigrita. The simplest chemical mixture was found in P. (C.) cylindricus (two compounds), while the most complex one was detected in P. (P.) nigrita (15 compounds). No significant differences in the chemical composition of the pygidial gland secretions were evidenced in P. (C.) cylindricus sampled from the same area and in the same season in two different years. Morphology of the pygidial glands of the studied species was analysed for the first time. Morphological features of the pygidial glands were observed using bright-field microscopy and nonlinear microscopy and described in details.
PB  - Elsevier
T2  - Zoology
T1  - Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae)
VL  - 142
SP  - 125772
DO  - 10.1016/j.zool.2020.125772
ER  - 

@article{
author = "Vranić, Sofija and Ćurčić, Srećko and Vesović, Nikola and Mandić, Boris and Pantelić, Dejan and Vasović, Marija and Lazović, Vladimir and Zhang, Wang and Vujisić, Ljubodrag V.",
year = "2020",
abstract = "Morphology of the pygidial glands and chemical composition of their secretions in adults of four ground beetle representatives of the Pterostichini tribe (Coleoptera: Carabidae) were analysed. Molops (Stenochoromus) montenegrinus, Pterostichus (Cophosus) cylindricus, P. (Feronidius) melas and P. (Pseudomaseus) nigrita were chemically tested, while the latter three species were morphologically investigated. Pterostichus (C.) cylindricus, P. (P.) nigrita and M. (S.) montenegrinus were chemically studied for the first time. Altogether, 23 chemical compounds were isolated using gas chromatography-mass spectrometry (GC-MS), of which some are new for Pterostichini or even Carabidae. Methacrylic acid was present in all species analysed. It was predominant in the secretion extract of P. (C.) cylindricus and P. (F.) melas. Isobutyric and 2-methylbutyric acids were the major components in the secretion of M. (S.) montenegrinus. Undecane, methacrylic and tiglic acids were the main components in the secretion of P. (P.) nigrita. The simplest chemical mixture was found in P. (C.) cylindricus (two compounds), while the most complex one was detected in P. (P.) nigrita (15 compounds). No significant differences in the chemical composition of the pygidial gland secretions were evidenced in P. (C.) cylindricus sampled from the same area and in the same season in two different years. Morphology of the pygidial glands of the studied species was analysed for the first time. Morphological features of the pygidial glands were observed using bright-field microscopy and nonlinear microscopy and described in details.",
publisher = "Elsevier",
journal = "Zoology",
title = "Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae)",
volume = "142",
pages = "125772",
doi = "10.1016/j.zool.2020.125772"
}

Vranić, S., Ćurčić, S., Vesović, N., Mandić, B., Pantelić, D., Vasović, M., Lazović, V., Zhang, W.,& Vujisić, L. V.. (2020). Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae). in Zoology
Elsevier., 142, 125772.
https://doi.org/10.1016/j.zool.2020.125772

Vranić S, Ćurčić S, Vesović N, Mandić B, Pantelić D, Vasović M, Lazović V, Zhang W, Vujisić LV. Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae). in Zoology. 2020;142:125772.
doi:10.1016/j.zool.2020.125772 .

Vranić, Sofija, Ćurčić, Srećko, Vesović, Nikola, Mandić, Boris, Pantelić, Dejan, Vasović, Marija, Lazović, Vladimir, Zhang, Wang, Vujisić, Ljubodrag V., "Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae)" in Zoology, 142 (2020):125772,
https://doi.org/10.1016/j.zool.2020.125772 . .

TY  - JOUR
AU  - Nikolić, Biljana M.
AU  - Đorđević, Iris
AU  - Todosijević, Marina
AU  - Mitić, Zorica S.
AU  - Bojović, Srdjan
AU  - Marin, Petar D.
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4059
AB  - The variability of n-alkanes in the needle cuticular wax of Pinus heldreichii and P. peuce in two natural populations from the Scardo-Pindic mountains was investigated for the first time. Gas chromatography (GC) and gas chromatography/mass spectrometry (GC-MS) analyses of two-year-old needles were performed us-ing an Agilent 7890A GC equipped with an inert 5975C XL EI/CI mass spectrometer detector (MSD) and a flame ionization detector (FID) connected by a capillary flow technology 2-way splitter with make-up. An HP-5MS capillary column was used. n-Alkanes ranged from C19 to C33. In P. heldreichii the most abundant were C23, C25 and C27 (16.3, 15.6 and 12.8 % on average, respectively), while in P. peuce they were C29, C25, and C27 (16.5, 15.3 and 13.5 % on average, resp.). Mid-chain and long-chain n-alkanes prevailed in both species. Principle component analysis (PCA) and Cluster analyses of five and six n-alkanes, respectively, showed divergence of the Scardo-Pindic populations from the Dinaric ones.
PB  - Macedonian Journal of Chemistry and Chemical Engineering
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Population Diversity of n–Alkanes in the Needle Cuticular Wax of Relicts Pinus heldreichii and P. peuce from the Scardo-Pindic Mountains
VL  - 39
IS  - 1
SP  - 41
EP  - 48
DO  - 10.20450/mjcce.2020.1951
ER  - 

@article{
author = "Nikolić, Biljana M. and Đorđević, Iris and Todosijević, Marina and Mitić, Zorica S. and Bojović, Srdjan and Marin, Petar D.",
year = "2020",
abstract = "The variability of n-alkanes in the needle cuticular wax of Pinus heldreichii and P. peuce in two natural populations from the Scardo-Pindic mountains was investigated for the first time. Gas chromatography (GC) and gas chromatography/mass spectrometry (GC-MS) analyses of two-year-old needles were performed us-ing an Agilent 7890A GC equipped with an inert 5975C XL EI/CI mass spectrometer detector (MSD) and a flame ionization detector (FID) connected by a capillary flow technology 2-way splitter with make-up. An HP-5MS capillary column was used. n-Alkanes ranged from C19 to C33. In P. heldreichii the most abundant were C23, C25 and C27 (16.3, 15.6 and 12.8 % on average, respectively), while in P. peuce they were C29, C25, and C27 (16.5, 15.3 and 13.5 % on average, resp.). Mid-chain and long-chain n-alkanes prevailed in both species. Principle component analysis (PCA) and Cluster analyses of five and six n-alkanes, respectively, showed divergence of the Scardo-Pindic populations from the Dinaric ones.",
publisher = "Macedonian Journal of Chemistry and Chemical Engineering",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Population Diversity of n–Alkanes in the Needle Cuticular Wax of Relicts Pinus heldreichii and P. peuce from the Scardo-Pindic Mountains",
volume = "39",
number = "1",
pages = "41-48",
doi = "10.20450/mjcce.2020.1951"
}

Nikolić, B. M., Đorđević, I., Todosijević, M., Mitić, Z. S., Bojović, S.,& Marin, P. D.. (2020). Population Diversity of n–Alkanes in the Needle Cuticular Wax of Relicts Pinus heldreichii and P. peuce from the Scardo-Pindic Mountains. in Macedonian Journal of Chemistry and Chemical Engineering
Macedonian Journal of Chemistry and Chemical Engineering., 39(1), 41-48.
https://doi.org/10.20450/mjcce.2020.1951

Nikolić BM, Đorđević I, Todosijević M, Mitić ZS, Bojović S, Marin PD. Population Diversity of n–Alkanes in the Needle Cuticular Wax of Relicts Pinus heldreichii and P. peuce from the Scardo-Pindic Mountains. in Macedonian Journal of Chemistry and Chemical Engineering. 2020;39(1):41-48.
doi:10.20450/mjcce.2020.1951 .

Nikolić, Biljana M., Đorđević, Iris, Todosijević, Marina, Mitić, Zorica S., Bojović, Srdjan, Marin, Petar D., "Population Diversity of n–Alkanes in the Needle Cuticular Wax of Relicts Pinus heldreichii and P. peuce from the Scardo-Pindic Mountains" in Macedonian Journal of Chemistry and Chemical Engineering, 39, no. 1 (2020):41-48,
https://doi.org/10.20450/mjcce.2020.1951 . .

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Todosijević, Marina
AU  - Đorđević, Iris
AU  - Stanković, Jovana
AU  - Mitić, Zorica S.
AU  - Tešević, Vele
AU  - Marin, Petar D.
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4237
AB  - In leaf cuticular wax of Pinus pinaster, content of nonacosan-10-ol is high (77.1% on average). n-Alkanes ranged from C18 to C35 with the most dominant C29 (24.8%). The carbon preference index (CPItotal) ranged from 3.1 to 5.6 (4.0 on average), while the average chain length (ACLtotal) ranged from 14.0 to 17.0 (14.8 on average). Long-chain n-alkanes (n-C25-35) strongly dominated (80.1%) over middle-chain (n-C21-24= 18.9%) and short-chain (n-C18-20= 0.9%) n-alkanes.
PB  - SAGE Publishing
T2  - Natural Product Communications
T1  - Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster
VL  - 15
IS  - 5
DO  - 10.1177/1934578X20926073
ER  - 

@article{
author = "Nikolić, Biljana and Todosijević, Marina and Đorđević, Iris and Stanković, Jovana and Mitić, Zorica S. and Tešević, Vele and Marin, Petar D.",
year = "2020",
abstract = "In leaf cuticular wax of Pinus pinaster, content of nonacosan-10-ol is high (77.1% on average). n-Alkanes ranged from C18 to C35 with the most dominant C29 (24.8%). The carbon preference index (CPItotal) ranged from 3.1 to 5.6 (4.0 on average), while the average chain length (ACLtotal) ranged from 14.0 to 17.0 (14.8 on average). Long-chain n-alkanes (n-C25-35) strongly dominated (80.1%) over middle-chain (n-C21-24= 18.9%) and short-chain (n-C18-20= 0.9%) n-alkanes.",
publisher = "SAGE Publishing",
journal = "Natural Product Communications",
title = "Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster",
volume = "15",
number = "5",
doi = "10.1177/1934578X20926073"
}

Nikolić, B., Todosijević, M., Đorđević, I., Stanković, J., Mitić, Z. S., Tešević, V.,& Marin, P. D.. (2020). Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster. in Natural Product Communications
SAGE Publishing., 15(5).
https://doi.org/10.1177/1934578X20926073

Nikolić B, Todosijević M, Đorđević I, Stanković J, Mitić ZS, Tešević V, Marin PD. Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster. in Natural Product Communications. 2020;15(5).
doi:10.1177/1934578X20926073 .

Nikolić, Biljana, Todosijević, Marina, Đorđević, Iris, Stanković, Jovana, Mitić, Zorica S., Tešević, Vele, Marin, Petar D., "Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster" in Natural Product Communications, 15, no. 5 (2020),
https://doi.org/10.1177/1934578X20926073 . .

TY  - JOUR
AU  - Vujić, Bojan
AU  - Vidaković, Vera
AU  - Jadranin, Milka
AU  - Novaković, Irena T.
AU  - Trifunović, Snežana S.
AU  - Tešević, Vele
AU  - Mandić, Boris
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3962
AB  - Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.
PB  - MDPI
T2  - Plants
T1  - Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts
VL  - 9
IS  - 3
SP  - 337
DO  - 10.3390/plants9030337
ER  - 

@article{
author = "Vujić, Bojan and Vidaković, Vera and Jadranin, Milka and Novaković, Irena T. and Trifunović, Snežana S. and Tešević, Vele and Mandić, Boris",
year = "2020",
abstract = "Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.",
publisher = "MDPI",
journal = "Plants",
title = "Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts",
volume = "9",
number = "3",
pages = "337",
doi = "10.3390/plants9030337"
}

Vujić, B., Vidaković, V., Jadranin, M., Novaković, I. T., Trifunović, S. S., Tešević, V.,& Mandić, B.. (2020). Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts. in Plants
MDPI., 9(3), 337.
https://doi.org/10.3390/plants9030337

Vujić B, Vidaković V, Jadranin M, Novaković IT, Trifunović SS, Tešević V, Mandić B. Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts. in Plants. 2020;9(3):337.
doi:10.3390/plants9030337 .

Vujić, Bojan, Vidaković, Vera, Jadranin, Milka, Novaković, Irena T., Trifunović, Snežana S., Tešević, Vele, Mandić, Boris, "Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts" in Plants, 9, no. 3 (2020):337,
https://doi.org/10.3390/plants9030337 . .

TY  - DATA
AU  - Novaković, Miroslav M.
AU  - Simić, Stefan
AU  - Koračak, Ljiljana
AU  - Zlatović, Mario
AU  - Ilić-Tomič, Tatjana
AU  - Asakawa, Yoshinori
AU  - Nikodinović-Runić, Jasmina
AU  - Opsenica, Igor
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3889
PB  - Elsevier
T2  - Fitoterapia
T1  - Supplementary data for the article: Novakovic, M.; Simić, S.; Koračak, L.; Zlatović, M.; Ilic-Tomic, T.; Asakawa, Y.; Nikodinovic-Runic, J.; Opsenica, I. Chemo- and Biocatalytic Esterification of Marchantin A and Cytotoxic Activity of Ester Derivatives. Fitoterapia 2020, 142. https://doi.org/10.1016/j.fitote.2020.104520.oxic activity of ester derivatives http://cherry.chem.bg.ac.rs/handle/123456789/3867
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3889
ER  - 

@misc{
author = "Novaković, Miroslav M. and Simić, Stefan and Koračak, Ljiljana and Zlatović, Mario and Ilić-Tomič, Tatjana and Asakawa, Yoshinori and Nikodinović-Runić, Jasmina and Opsenica, Igor",
year = "2020",
publisher = "Elsevier",
journal = "Fitoterapia",
title = "Supplementary data for the article: Novakovic, M.; Simić, S.; Koračak, L.; Zlatović, M.; Ilic-Tomic, T.; Asakawa, Y.; Nikodinovic-Runic, J.; Opsenica, I. Chemo- and Biocatalytic Esterification of Marchantin A and Cytotoxic Activity of Ester Derivatives. Fitoterapia 2020, 142. https://doi.org/10.1016/j.fitote.2020.104520.oxic activity of ester derivatives http://cherry.chem.bg.ac.rs/handle/123456789/3867",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3889"
}

Novaković, M. M., Simić, S., Koračak, L., Zlatović, M., Ilić-Tomič, T., Asakawa, Y., Nikodinović-Runić, J.,& Opsenica, I.. (2020). Supplementary data for the article: Novakovic, M.; Simić, S.; Koračak, L.; Zlatović, M.; Ilic-Tomic, T.; Asakawa, Y.; Nikodinovic-Runic, J.; Opsenica, I. Chemo- and Biocatalytic Esterification of Marchantin A and Cytotoxic Activity of Ester Derivatives. Fitoterapia 2020, 142. https://doi.org/10.1016/j.fitote.2020.104520.oxic activity of ester derivatives http://cherry.chem.bg.ac.rs/handle/123456789/3867. in Fitoterapia
Elsevier..
https://hdl.handle.net/21.15107/rcub_cherry_3889

Novaković MM, Simić S, Koračak L, Zlatović M, Ilić-Tomič T, Asakawa Y, Nikodinović-Runić J, Opsenica I. Supplementary data for the article: Novakovic, M.; Simić, S.; Koračak, L.; Zlatović, M.; Ilic-Tomic, T.; Asakawa, Y.; Nikodinovic-Runic, J.; Opsenica, I. Chemo- and Biocatalytic Esterification of Marchantin A and Cytotoxic Activity of Ester Derivatives. Fitoterapia 2020, 142. https://doi.org/10.1016/j.fitote.2020.104520.oxic activity of ester derivatives http://cherry.chem.bg.ac.rs/handle/123456789/3867. in Fitoterapia. 2020;.
https://hdl.handle.net/21.15107/rcub_cherry_3889 .

Novaković, Miroslav M., Simić, Stefan, Koračak, Ljiljana, Zlatović, Mario, Ilić-Tomič, Tatjana, Asakawa, Yoshinori, Nikodinović-Runić, Jasmina, Opsenica, Igor, "Supplementary data for the article: Novakovic, M.; Simić, S.; Koračak, L.; Zlatović, M.; Ilic-Tomic, T.; Asakawa, Y.; Nikodinovic-Runic, J.; Opsenica, I. Chemo- and Biocatalytic Esterification of Marchantin A and Cytotoxic Activity of Ester Derivatives. Fitoterapia 2020, 142. https://doi.org/10.1016/j.fitote.2020.104520.oxic activity of ester derivatives http://cherry.chem.bg.ac.rs/handle/123456789/3867" in Fitoterapia (2020),
https://hdl.handle.net/21.15107/rcub_cherry_3889 .

TY  - JOUR
AU  - Novaković, Miroslav M.
AU  - Simić, Stefan
AU  - Koračak, Ljiljana
AU  - Zlatović, Mario
AU  - Ilić-Tomič, Tatjana
AU  - Asakawa, Yoshinori
AU  - Nikodinović-Runić, Jasmina
AU  - Opsenica, Igor
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3890
AB  - Chemical and biocatalytic synthesis of seven previously undescribed marchantin A ester derivatives has been presented. Chemical synthesis afforded three peresterified bisbibenzyl products (TE1-TE3), while enzymatic method, using lipase, produced regioselective monoester derivatives (ME1-ME4). The antiproliferative activities of all prepared derivatives of marchantin A were tested on MRC-5 healthy human lung fibroblast, A549 human lung cancer, and MDA-MB-231 human breast cancer cell lines. All tested esters were less cytotoxic in comparison to marchantin A, but they also exhibited lower cytotoxicity against healthy cells. Monoesters displayed higher cytotoxic activities than the corresponding peresterified products, presumably due to the presence of free catechol group. Monohexanoyl ester ME3 displayed the same IC50 like marchantin A against MDA-MB-231 cells, but the selectivity was higher. In this way, regioselective enzymatic monoesterification enhanced selectivity of marchantin A. ME3 was also the most active among all derivatives against lung cancer cells A549 with the slightly lower activity and selectivity in comparison to marchantin A.
PB  - Elsevier
T2  - Fitoterapia
T1  - Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives
VL  - 142
SP  - 104520
DO  - 10.1016/j.fitote.2020.104520
ER  - 

@article{
author = "Novaković, Miroslav M. and Simić, Stefan and Koračak, Ljiljana and Zlatović, Mario and Ilić-Tomič, Tatjana and Asakawa, Yoshinori and Nikodinović-Runić, Jasmina and Opsenica, Igor",
year = "2020",
abstract = "Chemical and biocatalytic synthesis of seven previously undescribed marchantin A ester derivatives has been presented. Chemical synthesis afforded three peresterified bisbibenzyl products (TE1-TE3), while enzymatic method, using lipase, produced regioselective monoester derivatives (ME1-ME4). The antiproliferative activities of all prepared derivatives of marchantin A were tested on MRC-5 healthy human lung fibroblast, A549 human lung cancer, and MDA-MB-231 human breast cancer cell lines. All tested esters were less cytotoxic in comparison to marchantin A, but they also exhibited lower cytotoxicity against healthy cells. Monoesters displayed higher cytotoxic activities than the corresponding peresterified products, presumably due to the presence of free catechol group. Monohexanoyl ester ME3 displayed the same IC50 like marchantin A against MDA-MB-231 cells, but the selectivity was higher. In this way, regioselective enzymatic monoesterification enhanced selectivity of marchantin A. ME3 was also the most active among all derivatives against lung cancer cells A549 with the slightly lower activity and selectivity in comparison to marchantin A.",
publisher = "Elsevier",
journal = "Fitoterapia",
title = "Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives",
volume = "142",
pages = "104520",
doi = "10.1016/j.fitote.2020.104520"
}

Novaković, M. M., Simić, S., Koračak, L., Zlatović, M., Ilić-Tomič, T., Asakawa, Y., Nikodinović-Runić, J.,& Opsenica, I.. (2020). Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives. in Fitoterapia
Elsevier., 142, 104520.
https://doi.org/10.1016/j.fitote.2020.104520

Novaković MM, Simić S, Koračak L, Zlatović M, Ilić-Tomič T, Asakawa Y, Nikodinović-Runić J, Opsenica I. Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives. in Fitoterapia. 2020;142:104520.
doi:10.1016/j.fitote.2020.104520 .

Novaković, Miroslav M., Simić, Stefan, Koračak, Ljiljana, Zlatović, Mario, Ilić-Tomič, Tatjana, Asakawa, Yoshinori, Nikodinović-Runić, Jasmina, Opsenica, Igor, "Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives" in Fitoterapia, 142 (2020):104520,
https://doi.org/10.1016/j.fitote.2020.104520 . .

TY  - JOUR
AU  - Novaković, Miroslav M.
AU  - Ilić-Tomić, Tatjana
AU  - Tešević, Vele
AU  - Simić, Katarina
AU  - Ivanović, Stefan
AU  - Simić, Stefan
AU  - Opsenica, Igor
AU  - Nikodinović-Runić, Jasmina
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4052
AB  - The Trametes versicolor laccase catalyzed oxidation of chalcone butein afforded four dimers of aurone sulfuretin (i.e. two regioisomeric pairs of diasteromers, 1-4) as the major products. The formation of the dimers was explained by a two step process involving the initial cyclization of butein into aurone sulfuretin, followed by the combination of two molecules of sulfuretin. The coupling process occurred between the 2,10-double bond of one molecule of sulfuretin and the (3′,4′) catechol group of the other to yield a dimeric structure. This was confirmed by the experiment involving the laccase catalyzed oxidation of sulfuretin yielding the same dimeric bisaurones. Compounds 1, 3 and 4, were isolated using semipreparative HPLC and characterized by the detailed analysis of the NMR, MS, IR, and UV-vis data. The structure of compound 2, isolated as a mixture containing ca. 25% of compound 1, was proposed by the comparison of 1H NMR data to compound 1 and by using LC-ESIMS analysis. The starting chalcone butein and the products of the biocatalytic transformation, aurone sulfuretin and sulfuretin dimers 1, 3 and 4, were evaluated for their cytotoxic and antioxidative properties in vitro using a healthy human fibroblast (MRC5) cell line. The biotransformation products showed lower cytotoxicity but higher antioxidative properties. The C. coggygria bark methanol extract rich in butein and sulfuretin was also biotransformed by laccase. The transformed extract exhibited significantly improved antioxidative activities.
PB  - Royal Society of Chemistry
T2  - New Journal of Chemistry
T1  - Bisaurones – enzymatic production and biological evaluation
VL  - 44
IS  - 23
SP  - 9647
EP  - 9655
DO  - 10.1039/d0nj00758g
ER  - 

@article{
author = "Novaković, Miroslav M. and Ilić-Tomić, Tatjana and Tešević, Vele and Simić, Katarina and Ivanović, Stefan and Simić, Stefan and Opsenica, Igor and Nikodinović-Runić, Jasmina",
year = "2020",
abstract = "The Trametes versicolor laccase catalyzed oxidation of chalcone butein afforded four dimers of aurone sulfuretin (i.e. two regioisomeric pairs of diasteromers, 1-4) as the major products. The formation of the dimers was explained by a two step process involving the initial cyclization of butein into aurone sulfuretin, followed by the combination of two molecules of sulfuretin. The coupling process occurred between the 2,10-double bond of one molecule of sulfuretin and the (3′,4′) catechol group of the other to yield a dimeric structure. This was confirmed by the experiment involving the laccase catalyzed oxidation of sulfuretin yielding the same dimeric bisaurones. Compounds 1, 3 and 4, were isolated using semipreparative HPLC and characterized by the detailed analysis of the NMR, MS, IR, and UV-vis data. The structure of compound 2, isolated as a mixture containing ca. 25% of compound 1, was proposed by the comparison of 1H NMR data to compound 1 and by using LC-ESIMS analysis. The starting chalcone butein and the products of the biocatalytic transformation, aurone sulfuretin and sulfuretin dimers 1, 3 and 4, were evaluated for their cytotoxic and antioxidative properties in vitro using a healthy human fibroblast (MRC5) cell line. The biotransformation products showed lower cytotoxicity but higher antioxidative properties. The C. coggygria bark methanol extract rich in butein and sulfuretin was also biotransformed by laccase. The transformed extract exhibited significantly improved antioxidative activities.",
publisher = "Royal Society of Chemistry",
journal = "New Journal of Chemistry",
title = "Bisaurones – enzymatic production and biological evaluation",
volume = "44",
number = "23",
pages = "9647-9655",
doi = "10.1039/d0nj00758g"
}

Novaković, M. M., Ilić-Tomić, T., Tešević, V., Simić, K., Ivanović, S., Simić, S., Opsenica, I.,& Nikodinović-Runić, J.. (2020). Bisaurones – enzymatic production and biological evaluation. in New Journal of Chemistry
Royal Society of Chemistry., 44(23), 9647-9655.
https://doi.org/10.1039/d0nj00758g

Novaković MM, Ilić-Tomić T, Tešević V, Simić K, Ivanović S, Simić S, Opsenica I, Nikodinović-Runić J. Bisaurones – enzymatic production and biological evaluation. in New Journal of Chemistry. 2020;44(23):9647-9655.
doi:10.1039/d0nj00758g .

Novaković, Miroslav M., Ilić-Tomić, Tatjana, Tešević, Vele, Simić, Katarina, Ivanović, Stefan, Simić, Stefan, Opsenica, Igor, Nikodinović-Runić, Jasmina, "Bisaurones – enzymatic production and biological evaluation" in New Journal of Chemistry, 44, no. 23 (2020):9647-9655,
https://doi.org/10.1039/d0nj00758g . .

TY  - DATA
AU  - Novaković, Miroslav M.
AU  - Ilić-Tomić, Tatjana
AU  - Tešević, Vele
AU  - Simić, Katarina
AU  - Ivanović, Stefan
AU  - Simić, Stefan
AU  - Opsenica, Igor
AU  - Nikodinović-Runić, Jasmina
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4078
PB  - Royal Society of Chemistry
T2  - New Journal of Chemistry
T1  - Supplementary data for the article: Novakovic, M.; Ilic-Tomic, T.; Tesevic, V.; Simic, K.; Ivanovic, S.; Simic, S.; Opsenica, I.; Nikodinovic-Runic, J. Bisaurones – Enzymatic Production and Biological Evaluation. New J. Chem. 2020, 44 (23), 9647–9655. https://doi.org/10.1039/D0NJ00758G
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4078
ER  - 

@misc{
author = "Novaković, Miroslav M. and Ilić-Tomić, Tatjana and Tešević, Vele and Simić, Katarina and Ivanović, Stefan and Simić, Stefan and Opsenica, Igor and Nikodinović-Runić, Jasmina",
year = "2020",
publisher = "Royal Society of Chemistry",
journal = "New Journal of Chemistry",
title = "Supplementary data for the article: Novakovic, M.; Ilic-Tomic, T.; Tesevic, V.; Simic, K.; Ivanovic, S.; Simic, S.; Opsenica, I.; Nikodinovic-Runic, J. Bisaurones – Enzymatic Production and Biological Evaluation. New J. Chem. 2020, 44 (23), 9647–9655. https://doi.org/10.1039/D0NJ00758G",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4078"
}

Novaković, M. M., Ilić-Tomić, T., Tešević, V., Simić, K., Ivanović, S., Simić, S., Opsenica, I.,& Nikodinović-Runić, J.. (2020). Supplementary data for the article: Novakovic, M.; Ilic-Tomic, T.; Tesevic, V.; Simic, K.; Ivanovic, S.; Simic, S.; Opsenica, I.; Nikodinovic-Runic, J. Bisaurones – Enzymatic Production and Biological Evaluation. New J. Chem. 2020, 44 (23), 9647–9655. https://doi.org/10.1039/D0NJ00758G. in New Journal of Chemistry
Royal Society of Chemistry..
https://hdl.handle.net/21.15107/rcub_cherry_4078

Novaković MM, Ilić-Tomić T, Tešević V, Simić K, Ivanović S, Simić S, Opsenica I, Nikodinović-Runić J. Supplementary data for the article: Novakovic, M.; Ilic-Tomic, T.; Tesevic, V.; Simic, K.; Ivanovic, S.; Simic, S.; Opsenica, I.; Nikodinovic-Runic, J. Bisaurones – Enzymatic Production and Biological Evaluation. New J. Chem. 2020, 44 (23), 9647–9655. https://doi.org/10.1039/D0NJ00758G. in New Journal of Chemistry. 2020;.
https://hdl.handle.net/21.15107/rcub_cherry_4078 .

Novaković, Miroslav M., Ilić-Tomić, Tatjana, Tešević, Vele, Simić, Katarina, Ivanović, Stefan, Simić, Stefan, Opsenica, Igor, Nikodinović-Runić, Jasmina, "Supplementary data for the article: Novakovic, M.; Ilic-Tomic, T.; Tesevic, V.; Simic, K.; Ivanovic, S.; Simic, S.; Opsenica, I.; Nikodinovic-Runic, J. Bisaurones – Enzymatic Production and Biological Evaluation. New J. Chem. 2020, 44 (23), 9647–9655. https://doi.org/10.1039/D0NJ00758G" in New Journal of Chemistry (2020),
https://hdl.handle.net/21.15107/rcub_cherry_4078 .

TY  - JOUR
AU  - Novaković, Miroslav M.
AU  - Simić, Stefan
AU  - Koračak, Ljiljana
AU  - Zlatović, Mario
AU  - Ilić-Tomič, Tatjana
AU  - Asakawa, Yoshinori
AU  - Nikodinović-Runić, Jasmina
AU  - Opsenica, Igor
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3867
AB  - Chemical and biocatalytic synthesis of seven previously undescribed marchantin A ester derivatives has been presented. Chemical synthesis afforded three peresterified bisbibenzyl products (TE1-TE3), while enzymatic method, using lipase, produced regioselective monoester derivatives (ME1-ME4). The antiproliferative activities of all prepared derivatives of marchantin A were tested on MRC-5 healthy human lung fibroblast, A549 human lung cancer, and MDA-MB-231 human breast cancer cell lines. All tested esters were less cytotoxic in comparison to marchantin A, but they also exhibited lower cytotoxicity against healthy cells. Monoesters displayed higher cytotoxic activities than the corresponding peresterified products, presumably due to the presence of free catechol group. Monohexanoyl ester ME3 displayed the same IC50 like marchantin A against MDA-MB-231 cells, but the selectivity was higher. In this way, regioselective enzymatic monoesterification enhanced selectivity of marchantin A. ME3 was also the most active among all derivatives against lung cancer cells A549 with the slightly lower activity and selectivity in comparison to marchantin A.
PB  - Elsevier
T2  - Fitoterapia
T1  - Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives
VL  - 142
SP  - 104520
DO  - 10.1016/j.fitote.2020.104520
ER  - 

@article{
author = "Novaković, Miroslav M. and Simić, Stefan and Koračak, Ljiljana and Zlatović, Mario and Ilić-Tomič, Tatjana and Asakawa, Yoshinori and Nikodinović-Runić, Jasmina and Opsenica, Igor",
year = "2020",
abstract = "Chemical and biocatalytic synthesis of seven previously undescribed marchantin A ester derivatives has been presented. Chemical synthesis afforded three peresterified bisbibenzyl products (TE1-TE3), while enzymatic method, using lipase, produced regioselective monoester derivatives (ME1-ME4). The antiproliferative activities of all prepared derivatives of marchantin A were tested on MRC-5 healthy human lung fibroblast, A549 human lung cancer, and MDA-MB-231 human breast cancer cell lines. All tested esters were less cytotoxic in comparison to marchantin A, but they also exhibited lower cytotoxicity against healthy cells. Monoesters displayed higher cytotoxic activities than the corresponding peresterified products, presumably due to the presence of free catechol group. Monohexanoyl ester ME3 displayed the same IC50 like marchantin A against MDA-MB-231 cells, but the selectivity was higher. In this way, regioselective enzymatic monoesterification enhanced selectivity of marchantin A. ME3 was also the most active among all derivatives against lung cancer cells A549 with the slightly lower activity and selectivity in comparison to marchantin A.",
publisher = "Elsevier",
journal = "Fitoterapia",
title = "Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives",
volume = "142",
pages = "104520",
doi = "10.1016/j.fitote.2020.104520"
}

Novaković, M. M., Simić, S., Koračak, L., Zlatović, M., Ilić-Tomič, T., Asakawa, Y., Nikodinović-Runić, J.,& Opsenica, I.. (2020). Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives. in Fitoterapia
Elsevier., 142, 104520.
https://doi.org/10.1016/j.fitote.2020.104520

Novaković MM, Simić S, Koračak L, Zlatović M, Ilić-Tomič T, Asakawa Y, Nikodinović-Runić J, Opsenica I. Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives. in Fitoterapia. 2020;142:104520.
doi:10.1016/j.fitote.2020.104520 .

Novaković, Miroslav M., Simić, Stefan, Koračak, Ljiljana, Zlatović, Mario, Ilić-Tomič, Tatjana, Asakawa, Yoshinori, Nikodinović-Runić, Jasmina, Opsenica, Igor, "Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives" in Fitoterapia, 142 (2020):104520,
https://doi.org/10.1016/j.fitote.2020.104520 . .

TY  - JOUR
AU  - Cvetković, Mirjana
AU  - Damjanović, Ana
AU  - Stanojković, Tatjana
AU  - Đorđević, Iris
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan M.
AU  - Gođevac, Dejan
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3348
AB  - Metabolomics generate a profile of small molecules from plant extracts, which could be directly responsible for bioactivity effects. Using dry-column flash chromatography enabled a rapid and inexpensive method for the very efficient separation of plant extract with a high resolution. This separation method coupled to NMR and FTIR-based metabolomics is applied to identify bioactive natural products. OPLS multivariate analysis method, was used for correlation the chemical composition of the plant extracts, Amphoricarpos autariatus, with the results of cytotoxic activity against Human cervical adenocarcinoma cell line (HeLa) and epithelial lung cancer cell line (A549). In this way, the highest contribution to the cytotoxic activity was recorded for the guaianolide sesquiterpene lactones named amphoricarpolides. The compounds indicated as bioactive after metabolomics analysis were tested, and their cytotoxic activity were confirmed.
T2  - Talanta
T1  - Integration of dry-column flash chromatography with NMR and FTIR metabolomics to reveal cytotoxic metabolites from Amphoricarpos autariatus
VL  - 206
SP  - 1
EP  - 6
DO  - 10.1016/j.talanta.2019.120248
ER  - 

@article{
author = "Cvetković, Mirjana and Damjanović, Ana and Stanojković, Tatjana and Đorđević, Iris and Tešević, Vele and Milosavljević, Slobodan M. and Gođevac, Dejan",
year = "2020",
abstract = "Metabolomics generate a profile of small molecules from plant extracts, which could be directly responsible for bioactivity effects. Using dry-column flash chromatography enabled a rapid and inexpensive method for the very efficient separation of plant extract with a high resolution. This separation method coupled to NMR and FTIR-based metabolomics is applied to identify bioactive natural products. OPLS multivariate analysis method, was used for correlation the chemical composition of the plant extracts, Amphoricarpos autariatus, with the results of cytotoxic activity against Human cervical adenocarcinoma cell line (HeLa) and epithelial lung cancer cell line (A549). In this way, the highest contribution to the cytotoxic activity was recorded for the guaianolide sesquiterpene lactones named amphoricarpolides. The compounds indicated as bioactive after metabolomics analysis were tested, and their cytotoxic activity were confirmed.",
journal = "Talanta",
title = "Integration of dry-column flash chromatography with NMR and FTIR metabolomics to reveal cytotoxic metabolites from Amphoricarpos autariatus",
volume = "206",
pages = "1-6",
doi = "10.1016/j.talanta.2019.120248"
}

Cvetković, M., Damjanović, A., Stanojković, T., Đorđević, I., Tešević, V., Milosavljević, S. M.,& Gođevac, D.. (2020). Integration of dry-column flash chromatography with NMR and FTIR metabolomics to reveal cytotoxic metabolites from Amphoricarpos autariatus. in Talanta, 206, 1-6.
https://doi.org/10.1016/j.talanta.2019.120248

Cvetković M, Damjanović A, Stanojković T, Đorđević I, Tešević V, Milosavljević SM, Gođevac D. Integration of dry-column flash chromatography with NMR and FTIR metabolomics to reveal cytotoxic metabolites from Amphoricarpos autariatus. in Talanta. 2020;206:1-6.
doi:10.1016/j.talanta.2019.120248 .

Cvetković, Mirjana, Damjanović, Ana, Stanojković, Tatjana, Đorđević, Iris, Tešević, Vele, Milosavljević, Slobodan M., Gođevac, Dejan, "Integration of dry-column flash chromatography with NMR and FTIR metabolomics to reveal cytotoxic metabolites from Amphoricarpos autariatus" in Talanta, 206 (2020):1-6,
https://doi.org/10.1016/j.talanta.2019.120248 . .

TY  - DATA
AU  - Cvetković, Mirjana
AU  - Damjanović, Ana
AU  - Stanojković, Tatjana
AU  - Đorđević, Iris
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan M.
AU  - Gođevac, Dejan
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3349
T2  - Talanta
T1  - Supplementary material for the article: Cvetković, M.; Damjanović, A.; Stanojković, T. P.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. Integration of Dry-Column Flash Chromatography with NMR and FTIR Metabolomics to Reveal Cytotoxic Metabolites from Amphoricarpos Autariatus. Talanta 2020, 206. https://doi.org/10.1016/j.talanta.2019.120248
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3349
ER  - 

@misc{
author = "Cvetković, Mirjana and Damjanović, Ana and Stanojković, Tatjana and Đorđević, Iris and Tešević, Vele and Milosavljević, Slobodan M. and Gođevac, Dejan",
year = "2020",
journal = "Talanta",
title = "Supplementary material for the article: Cvetković, M.; Damjanović, A.; Stanojković, T. P.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. Integration of Dry-Column Flash Chromatography with NMR and FTIR Metabolomics to Reveal Cytotoxic Metabolites from Amphoricarpos Autariatus. Talanta 2020, 206. https://doi.org/10.1016/j.talanta.2019.120248",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3349"
}

Cvetković, M., Damjanović, A., Stanojković, T., Đorđević, I., Tešević, V., Milosavljević, S. M.,& Gođevac, D.. (2020). Supplementary material for the article: Cvetković, M.; Damjanović, A.; Stanojković, T. P.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. Integration of Dry-Column Flash Chromatography with NMR and FTIR Metabolomics to Reveal Cytotoxic Metabolites from Amphoricarpos Autariatus. Talanta 2020, 206. https://doi.org/10.1016/j.talanta.2019.120248. in Talanta.
https://hdl.handle.net/21.15107/rcub_cherry_3349

Cvetković M, Damjanović A, Stanojković T, Đorđević I, Tešević V, Milosavljević SM, Gođevac D. Supplementary material for the article: Cvetković, M.; Damjanović, A.; Stanojković, T. P.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. Integration of Dry-Column Flash Chromatography with NMR and FTIR Metabolomics to Reveal Cytotoxic Metabolites from Amphoricarpos Autariatus. Talanta 2020, 206. https://doi.org/10.1016/j.talanta.2019.120248. in Talanta. 2020;.
https://hdl.handle.net/21.15107/rcub_cherry_3349 .

Cvetković, Mirjana, Damjanović, Ana, Stanojković, Tatjana, Đorđević, Iris, Tešević, Vele, Milosavljević, Slobodan M., Gođevac, Dejan, "Supplementary material for the article: Cvetković, M.; Damjanović, A.; Stanojković, T. P.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. Integration of Dry-Column Flash Chromatography with NMR and FTIR Metabolomics to Reveal Cytotoxic Metabolites from Amphoricarpos Autariatus. Talanta 2020, 206. https://doi.org/10.1016/j.talanta.2019.120248" in Talanta (2020),
https://hdl.handle.net/21.15107/rcub_cherry_3349 .

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Matović, Milić
AU  - Mladenović, Katarina
AU  - Todosijević, Marina
AU  - Stanković, Jovana
AU  - Đorđević, Iris
AU  - Marin, Petar D.
AU  - Tešević, Vele
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3267
AB  - Volatiles of Thymus serpyllum L. were obtained by hydrodistillation (HD), simultaneous hydrodistillation, and extraction (SDE) and static headspace gas chromatography-mass spectrometry analysis (head space [HS]), respectively. Monoterpenes were the most dominant in all 3 techniques (84.8%-94.2%). Essential oil profiles obtained by HD and SDE were similar, with oxygenated monoterpenes being the most abundant (up to 75.4%). In HS volatiles of T. serpyllum monoterpene hydrocarbons strongly dominated (94.2%). The main compounds were α-terpinyl acetate (HD and SDE) and myrcene (HS).
T2  - Natural Product Communications
T1  - Volatiles of Thymus serpyllum Obtained by Three Different Methods
VL  - 14
IS  - 6
DO  - 10.1177/1934578X19856254
ER  - 

@article{
author = "Nikolić, Biljana and Matović, Milić and Mladenović, Katarina and Todosijević, Marina and Stanković, Jovana and Đorđević, Iris and Marin, Petar D. and Tešević, Vele",
year = "2019",
abstract = "Volatiles of Thymus serpyllum L. were obtained by hydrodistillation (HD), simultaneous hydrodistillation, and extraction (SDE) and static headspace gas chromatography-mass spectrometry analysis (head space [HS]), respectively. Monoterpenes were the most dominant in all 3 techniques (84.8%-94.2%). Essential oil profiles obtained by HD and SDE were similar, with oxygenated monoterpenes being the most abundant (up to 75.4%). In HS volatiles of T. serpyllum monoterpene hydrocarbons strongly dominated (94.2%). The main compounds were α-terpinyl acetate (HD and SDE) and myrcene (HS).",
journal = "Natural Product Communications",
title = "Volatiles of Thymus serpyllum Obtained by Three Different Methods",
volume = "14",
number = "6",
doi = "10.1177/1934578X19856254"
}

Nikolić, B., Matović, M., Mladenović, K., Todosijević, M., Stanković, J., Đorđević, I., Marin, P. D.,& Tešević, V.. (2019). Volatiles of Thymus serpyllum Obtained by Three Different Methods. in Natural Product Communications, 14(6).
https://doi.org/10.1177/1934578X19856254

Nikolić B, Matović M, Mladenović K, Todosijević M, Stanković J, Đorđević I, Marin PD, Tešević V. Volatiles of Thymus serpyllum Obtained by Three Different Methods. in Natural Product Communications. 2019;14(6).
doi:10.1177/1934578X19856254 .

Nikolić, Biljana, Matović, Milić, Mladenović, Katarina, Todosijević, Marina, Stanković, Jovana, Đorđević, Iris, Marin, Petar D., Tešević, Vele, "Volatiles of Thymus serpyllum Obtained by Three Different Methods" in Natural Product Communications, 14, no. 6 (2019),
https://doi.org/10.1177/1934578X19856254 . .

TY  - THES
AU  - Stanković, Jovana
PY  - 2019
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=7015
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:20623/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=51738383
UR  - http://nardus.mpn.gov.rs/123456789/11672
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3909
AB  - Predmet proučavanja ove doktorske disertacije su sekundarni metaboliti halofita(biljaka koje naseljavaju staništa sa visokim sadržajem soli). U Srbiji se zaslanjenastaništa uglavnom javljaju na teritoriji Vojvodine. U ovom radu izolovani su i hemijskiokarakterisani flavonoidni glikozidi i saponini iz halofitnih vrsta roda Atriplex (A.littoralis, A. tatarica i A. prostrata) i određena je njihova različita biološka aktivnost.Pored biljaka iz roda Atriplex ispitivana je halofitna biljna vrsta Artemisia santonicum izkoje je izolovano etarsko ulje, određen hemijski sastav i ispitana biološka aktivnost.Halofitne biljne vrste se u tradicionalnoj medicini koriste u brojne svrhe kaoantiseptici, diuretici, antiparazitici, antipiretici, purgativi, laksativi, za lečenjedijabetesa, visokog krvnog pritiska, astme, gihta i reumatizma. Ekstrakti i jedinjenjaizolovana iz vrsta roda Atriplex pokazuju antioksidativnu, antimikrobnu, citotoksičnu,antiparazitsku, i insekticidnu aktivnost. Etarska ulja vrsta roda Artemisia su pokazalaantioksidativnu, antibakterijsku, antifungalnu, antiparazitsku, hepatoprotektivnu,neuroprotektivnu i antimalarijsku aktivnost.Vrste roda Atriplex su bogat izvor sekundarnih metabolita prvenstvenoflavonoida, saponina i alkaloida. U okviru ove disertacije izolovano je i okarakterisanoukupno 13 jedinjenja, od kojih je 7 novih prirodnih proizvoda (43-45, 51-54). Iz vrste A.littoralis izolovano je 6 jedinjenja, četiri flavonoidna glikozida (43-46) i dva fenolnajedinjenja (47, 48). Iz A. tatarica izolovano je 6 jedinjenja, tri flavonoidna glikozida(49-51) i tri triterpenska saponina oleanolnog tipa (52-54). Iz etarskog ulja Artemisiasantonicum izolovan je oksigenovani monoterpen (55)...
AB  - The subject of this doctoral dissertation are the secondary metabolites ofhalophytes (plants wild growing at saline habitats). In Serbia such habitats are mainlyfound in Vojvodina. Flavonoid glycosides and saponins from halophytic speciesAtriplex (A. littoralis, A. tatarica and A. prostrata) were isolated, chemicallycharacterized and their various biological activities were determined. In addition, ahalophyte species from the genus Artemisia (A. santonicum) was examined. Its essentialoil was isolated, the chemical composition determined and various biological activitiesof this were tested.Several halophytic plant species are used in many traditional formulations asantiseptics, diuretics, antiparasitics, antipyretics, purgatives, laxatives, for the treatmentof diabetes, high blood pressure, asthma, gout and rheumatism. Extracts and compoundsisolated from the genus Atriplex show antiparasitic, insecticidal, antimicrobial,cytotoxic and antioxidant activity. Essential oils of the genus Artemisia have shownantioxidant, antibacterial, antifungal, antiparasitic, hepatoprotective, neuroprotectiveand antimalarial activity.Atriplex species are a rich source of secondary metabolites, primarily flavonoids,saponins and alkaloids. In this study, a total of 13 compounds were isolated andcharacterized by means of spectroscopic techniques (1D and 2D NMR, IR and MS).Among them seven (43-45, 51-54) were the new compounds. At the same time, in theextract of A. littoralis, six compounds, four flavonoid glycosides (43-46) and twophenolic compounds (47, 48) were identified. From A. tatarica six compounds, threeflavonoid glycosides (49-51) and three triterpene saponins of an oleanane type (52-54)were isolated. An oxygenated monoterpene (55) was isolated from Artemisiasantonicum essential oil...
PB  - Универзитет у Београду, Хемијски факултет
T2  - Универзитет у Београду
T1  - Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita
UR  - https://hdl.handle.net/21.15107/rcub_nardus_11672
ER  - 

@phdthesis{
author = "Stanković, Jovana",
year = "2019",
abstract = "Predmet proučavanja ove doktorske disertacije su sekundarni metaboliti halofita(biljaka koje naseljavaju staništa sa visokim sadržajem soli). U Srbiji se zaslanjenastaništa uglavnom javljaju na teritoriji Vojvodine. U ovom radu izolovani su i hemijskiokarakterisani flavonoidni glikozidi i saponini iz halofitnih vrsta roda Atriplex (A.littoralis, A. tatarica i A. prostrata) i određena je njihova različita biološka aktivnost.Pored biljaka iz roda Atriplex ispitivana je halofitna biljna vrsta Artemisia santonicum izkoje je izolovano etarsko ulje, određen hemijski sastav i ispitana biološka aktivnost.Halofitne biljne vrste se u tradicionalnoj medicini koriste u brojne svrhe kaoantiseptici, diuretici, antiparazitici, antipiretici, purgativi, laksativi, za lečenjedijabetesa, visokog krvnog pritiska, astme, gihta i reumatizma. Ekstrakti i jedinjenjaizolovana iz vrsta roda Atriplex pokazuju antioksidativnu, antimikrobnu, citotoksičnu,antiparazitsku, i insekticidnu aktivnost. Etarska ulja vrsta roda Artemisia su pokazalaantioksidativnu, antibakterijsku, antifungalnu, antiparazitsku, hepatoprotektivnu,neuroprotektivnu i antimalarijsku aktivnost.Vrste roda Atriplex su bogat izvor sekundarnih metabolita prvenstvenoflavonoida, saponina i alkaloida. U okviru ove disertacije izolovano je i okarakterisanoukupno 13 jedinjenja, od kojih je 7 novih prirodnih proizvoda (43-45, 51-54). Iz vrste A.littoralis izolovano je 6 jedinjenja, četiri flavonoidna glikozida (43-46) i dva fenolnajedinjenja (47, 48). Iz A. tatarica izolovano je 6 jedinjenja, tri flavonoidna glikozida(49-51) i tri triterpenska saponina oleanolnog tipa (52-54). Iz etarskog ulja Artemisiasantonicum izolovan je oksigenovani monoterpen (55)..., The subject of this doctoral dissertation are the secondary metabolites ofhalophytes (plants wild growing at saline habitats). In Serbia such habitats are mainlyfound in Vojvodina. Flavonoid glycosides and saponins from halophytic speciesAtriplex (A. littoralis, A. tatarica and A. prostrata) were isolated, chemicallycharacterized and their various biological activities were determined. In addition, ahalophyte species from the genus Artemisia (A. santonicum) was examined. Its essentialoil was isolated, the chemical composition determined and various biological activitiesof this were tested.Several halophytic plant species are used in many traditional formulations asantiseptics, diuretics, antiparasitics, antipyretics, purgatives, laxatives, for the treatmentof diabetes, high blood pressure, asthma, gout and rheumatism. Extracts and compoundsisolated from the genus Atriplex show antiparasitic, insecticidal, antimicrobial,cytotoxic and antioxidant activity. Essential oils of the genus Artemisia have shownantioxidant, antibacterial, antifungal, antiparasitic, hepatoprotective, neuroprotectiveand antimalarial activity.Atriplex species are a rich source of secondary metabolites, primarily flavonoids,saponins and alkaloids. In this study, a total of 13 compounds were isolated andcharacterized by means of spectroscopic techniques (1D and 2D NMR, IR and MS).Among them seven (43-45, 51-54) were the new compounds. At the same time, in theextract of A. littoralis, six compounds, four flavonoid glycosides (43-46) and twophenolic compounds (47, 48) were identified. From A. tatarica six compounds, threeflavonoid glycosides (49-51) and three triterpene saponins of an oleanane type (52-54)were isolated. An oxygenated monoterpene (55) was isolated from Artemisiasantonicum essential oil...",
publisher = "Универзитет у Београду, Хемијски факултет",
journal = "Универзитет у Београду",
title = "Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita",
url = "https://hdl.handle.net/21.15107/rcub_nardus_11672"
}

Stanković, J.. (2019). Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita. in Универзитет у Београду
Универзитет у Београду, Хемијски факултет..
https://hdl.handle.net/21.15107/rcub_nardus_11672

Stanković J. Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita. in Универзитет у Београду. 2019;.
https://hdl.handle.net/21.15107/rcub_nardus_11672 .

Stanković, Jovana, "Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita" in Универзитет у Београду (2019),
https://hdl.handle.net/21.15107/rcub_nardus_11672 .

TY  - THES
AU  - Krstić, Gordana B.
PY  - 2019
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=7722
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:22941/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=23933961
UR  - https://nardus.mpn.gov.rs/handle/123456789/17673
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4378
AB  - Predmet ove doktorske disertacije je proučavanje sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia koje nastanjuju naše prostore. Za ispitivanje su odabrane Euphorbia palustris L. (barska mlečika), Eupohorbia lucida Waldst. & Kit. (visoka mlečika) i Euphorbia nicaeensis All (uskolisna mlečika). Biljne vrste roda Euphorbia poznate su od davnina i našle su svoju praktičnu primenu u tradicionalnoj i savremenoj medicini. Za sve predstavnike ovog roda karakteristično je postojanje biljnog soka (lateks) koji se skadišti u posebnim ćelijama koje se nalaze u stablu i listovima biljaka. Lateks predstavlja vodenu emulziju smeše terpena, fenolnih jedinjenja, cerebrozida, glicerola i drugih jedinjenja koja ima zaštitno dejstvo za biljku. Najzastupljenija jedinjenja u lateksu pripadaju klasi terpena i to diterpenima i triterpenima...
AB  - The subject of this doctoral dissertation is the study of secondary metabolites of selected plant species of the genus Euphorbia that grow in our region. Euphorbia palustris L. (swamp spurge), Euphorbia lucida Waldst. & Kit. (shining spurge) and Euphorbia nicaeensis All. (narrow-leaved spurge) were selected for the research. Plant species of the genus Euphorbia have been known since ancient times and have found practical applications in traditional and modern medicine. All the plants of this genus are characterized by the existence of a milky sap (latex) which is stored in specialized cells found in the stem and leaves of the plants. Latex is an aqueous emulsion of a mixture of terpenes, phenolic compounds, cerebrosides, glycerols and other compounds that has a protective effect on the plant. Terpenes are the major components of the latex, namely diterpenes and triterpenes...
PB  - Универзитет у Београду, Хемијски факултет
T2  - Универзитет у Београду
T1  - Ispitivanje hemijskog sastava sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia
UR  - https://hdl.handle.net/21.15107/rcub_nardus_17673
ER  - 

@phdthesis{
author = "Krstić, Gordana B.",
year = "2019",
abstract = "Predmet ove doktorske disertacije je proučavanje sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia koje nastanjuju naše prostore. Za ispitivanje su odabrane Euphorbia palustris L. (barska mlečika), Eupohorbia lucida Waldst. & Kit. (visoka mlečika) i Euphorbia nicaeensis All (uskolisna mlečika). Biljne vrste roda Euphorbia poznate su od davnina i našle su svoju praktičnu primenu u tradicionalnoj i savremenoj medicini. Za sve predstavnike ovog roda karakteristično je postojanje biljnog soka (lateks) koji se skadišti u posebnim ćelijama koje se nalaze u stablu i listovima biljaka. Lateks predstavlja vodenu emulziju smeše terpena, fenolnih jedinjenja, cerebrozida, glicerola i drugih jedinjenja koja ima zaštitno dejstvo za biljku. Najzastupljenija jedinjenja u lateksu pripadaju klasi terpena i to diterpenima i triterpenima..., The subject of this doctoral dissertation is the study of secondary metabolites of selected plant species of the genus Euphorbia that grow in our region. Euphorbia palustris L. (swamp spurge), Euphorbia lucida Waldst. & Kit. (shining spurge) and Euphorbia nicaeensis All. (narrow-leaved spurge) were selected for the research. Plant species of the genus Euphorbia have been known since ancient times and have found practical applications in traditional and modern medicine. All the plants of this genus are characterized by the existence of a milky sap (latex) which is stored in specialized cells found in the stem and leaves of the plants. Latex is an aqueous emulsion of a mixture of terpenes, phenolic compounds, cerebrosides, glycerols and other compounds that has a protective effect on the plant. Terpenes are the major components of the latex, namely diterpenes and triterpenes...",
publisher = "Универзитет у Београду, Хемијски факултет",
journal = "Универзитет у Београду",
title = "Ispitivanje hemijskog sastava sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia",
url = "https://hdl.handle.net/21.15107/rcub_nardus_17673"
}

Krstić, G. B.. (2019). Ispitivanje hemijskog sastava sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia. in Универзитет у Београду
Универзитет у Београду, Хемијски факултет..
https://hdl.handle.net/21.15107/rcub_nardus_17673

Krstić GB. Ispitivanje hemijskog sastava sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia. in Универзитет у Београду. 2019;.
https://hdl.handle.net/21.15107/rcub_nardus_17673 .

Krstić, Gordana B., "Ispitivanje hemijskog sastava sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia" in Универзитет у Београду (2019),
https://hdl.handle.net/21.15107/rcub_nardus_17673 .

TY  - JOUR
AU  - Cvetković, Mirjana
AU  - Đorđević, Iris
AU  - Jadranin, Milka
AU  - Stanković, Miroslava
AU  - Mandić, Boris
AU  - Milosavljević, Slobodan M.
AU  - Vujisić, Ljubodrag V.
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4938
AB  - Analysis of composition of CH2Cl2 surface extract of leaves of Amphoricarpos neumayeri Vis. revealed 16 sesquiterpene lactones with guaianolide skeleton, so called amphoricarpolides, typical for this genus. Four of them, 13–16, were new derivatives and their structures were elucidated by detailed analyses of IR, NMR and MS data. Amphoricarpolide (9), its 15-O-acetyl derivative (5), and two 9β-hydroxyamphoricarpolides, 3,15-di-O-acetyl- and 3-O-acetyl-15-O-isovaleroyl derivatives (3 and 6, respectively) were tested for in vitro protective effect on chromosome aberrations in peripheral human lymphocytes using cytochalasin-B blocked micronucleus (CBMN) assay. The tested compound exerted a beneficial effect by decreasing DNA damage of human lymphocytes.
PB  - Informa UK Limited
T2  - Natural Product Research
T1  - Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA
SP  - 1
EP  - 9
DO  - 10.1080/14786419.2019.1687470
ER  - 

@article{
author = "Cvetković, Mirjana and Đorđević, Iris and Jadranin, Milka and Stanković, Miroslava and Mandić, Boris and Milosavljević, Slobodan M. and Vujisić, Ljubodrag V.",
year = "2019",
abstract = "Analysis of composition of CH2Cl2 surface extract of leaves of Amphoricarpos neumayeri Vis. revealed 16 sesquiterpene lactones with guaianolide skeleton, so called amphoricarpolides, typical for this genus. Four of them, 13–16, were new derivatives and their structures were elucidated by detailed analyses of IR, NMR and MS data. Amphoricarpolide (9), its 15-O-acetyl derivative (5), and two 9β-hydroxyamphoricarpolides, 3,15-di-O-acetyl- and 3-O-acetyl-15-O-isovaleroyl derivatives (3 and 6, respectively) were tested for in vitro protective effect on chromosome aberrations in peripheral human lymphocytes using cytochalasin-B blocked micronucleus (CBMN) assay. The tested compound exerted a beneficial effect by decreasing DNA damage of human lymphocytes.",
publisher = "Informa UK Limited",
journal = "Natural Product Research",
title = "Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA",
pages = "1-9",
doi = "10.1080/14786419.2019.1687470"
}

Cvetković, M., Đorđević, I., Jadranin, M., Stanković, M., Mandić, B., Milosavljević, S. M.,& Vujisić, L. V.. (2019). Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA. in Natural Product Research
Informa UK Limited., 1-9.
https://doi.org/10.1080/14786419.2019.1687470

Cvetković M, Đorđević I, Jadranin M, Stanković M, Mandić B, Milosavljević SM, Vujisić LV. Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA. in Natural Product Research. 2019;:1-9.
doi:10.1080/14786419.2019.1687470 .

Cvetković, Mirjana, Đorđević, Iris, Jadranin, Milka, Stanković, Miroslava, Mandić, Boris, Milosavljević, Slobodan M., Vujisić, Ljubodrag V., "Leaf-surface guaianolides from Amphoricarpos neumaeyri                    showing protective effect on human lymphocytes DNA" in Natural Product Research (2019):1-9,
https://doi.org/10.1080/14786419.2019.1687470 . .

TY  - JOUR
AU  - Stanković, Jovana
AU  - Gođevac, Dejan
AU  - Tešević, Vele
AU  - Dajić-Stevanović, Zora
AU  - Ćirić, Ana D.
AU  - Soković, Marina
AU  - Novaković, Miroslav M.
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3725
AB  - A new flavonoid glucoside derivative, patuletin 3-O-(2-O-feruloyl)-β-d-glucuronopyranosyl-(1→2)-β-d-glucopyranoside, named atriplexin IV (1), and three new triterpenoid saponin derivatives, two sulfonylated, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside-30-alolean-12-en-28-oate (2), named atriplexogenin I, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside)-30-hydroxyolean-12-en-28-oate (3), named atriplexogenin II, and β-d-glucopyranosyl-3-O-(β-d-glucopyranosyl-(1→2)-β-d-galactopyranosyl-(1→2)-α-l-arabinopyranoside)-30-alolean-12-en-28-oate (4), named atriplexogenin III, were isolated by silica gel column and semipreparative HPLC chromatography from the n-butanol extract of the salt marsh plant Atriplex tatarica. In addition, two known secondary metabolites, patuletin3-O-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (5) and patuletin 3-O-5'-O-feruloyl-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (6), were isolated for the first time from A. tatarica. The structures of the isolated compounds were elucidated by 1D and 2D NMR, HRESIMS, IR, and UV data. Antibacterial activity by the microdilution method and antibiofilm activity against P. aeruginosa were assessed. Compound 5 possesses significant antibacterial activity, while the most potent antibiofilm agent is compound 2.
PB  - American Chemical Society
T2  - Journal of Natural Products
T1  - Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa
VL  - 82
IS  - 6
SP  - 1487
EP  - 1495
DO  - 10.1021/acs.jnatprod.8b00970
ER  - 

@article{
author = "Stanković, Jovana and Gođevac, Dejan and Tešević, Vele and Dajić-Stevanović, Zora and Ćirić, Ana D. and Soković, Marina and Novaković, Miroslav M.",
year = "2019",
abstract = "A new flavonoid glucoside derivative, patuletin 3-O-(2-O-feruloyl)-β-d-glucuronopyranosyl-(1→2)-β-d-glucopyranoside, named atriplexin IV (1), and three new triterpenoid saponin derivatives, two sulfonylated, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside-30-alolean-12-en-28-oate (2), named atriplexogenin I, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside)-30-hydroxyolean-12-en-28-oate (3), named atriplexogenin II, and β-d-glucopyranosyl-3-O-(β-d-glucopyranosyl-(1→2)-β-d-galactopyranosyl-(1→2)-α-l-arabinopyranoside)-30-alolean-12-en-28-oate (4), named atriplexogenin III, were isolated by silica gel column and semipreparative HPLC chromatography from the n-butanol extract of the salt marsh plant Atriplex tatarica. In addition, two known secondary metabolites, patuletin3-O-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (5) and patuletin 3-O-5'-O-feruloyl-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (6), were isolated for the first time from A. tatarica. The structures of the isolated compounds were elucidated by 1D and 2D NMR, HRESIMS, IR, and UV data. Antibacterial activity by the microdilution method and antibiofilm activity against P. aeruginosa were assessed. Compound 5 possesses significant antibacterial activity, while the most potent antibiofilm agent is compound 2.",
publisher = "American Chemical Society",
journal = "Journal of Natural Products",
title = "Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa",
volume = "82",
number = "6",
pages = "1487-1495",
doi = "10.1021/acs.jnatprod.8b00970"
}

Stanković, J., Gođevac, D., Tešević, V., Dajić-Stevanović, Z., Ćirić, A. D., Soković, M.,& Novaković, M. M.. (2019). Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. in Journal of Natural Products
American Chemical Society., 82(6), 1487-1495.
https://doi.org/10.1021/acs.jnatprod.8b00970

Stanković J, Gođevac D, Tešević V, Dajić-Stevanović Z, Ćirić AD, Soković M, Novaković MM. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. in Journal of Natural Products. 2019;82(6):1487-1495.
doi:10.1021/acs.jnatprod.8b00970 .

Stanković, Jovana, Gođevac, Dejan, Tešević, Vele, Dajić-Stevanović, Zora, Ćirić, Ana D., Soković, Marina, Novaković, Miroslav M., "Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa" in Journal of Natural Products, 82, no. 6 (2019):1487-1495,
https://doi.org/10.1021/acs.jnatprod.8b00970 . .

TY  - DATA
AU  - Stanković, Jovana
AU  - Gođevac, Dejan
AU  - Tešević, Vele
AU  - Dajić-Stevanović, Zora
AU  - Ćirić, Ana D.
AU  - Soković, Marina
AU  - Novaković, Miroslav M.
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3726
PB  - American Chemical Society
T2  - Journal of Natural Products
T1  - Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3726
ER  - 

@misc{
author = "Stanković, Jovana and Gođevac, Dejan and Tešević, Vele and Dajić-Stevanović, Zora and Ćirić, Ana D. and Soković, Marina and Novaković, Miroslav M.",
year = "2019",
publisher = "American Chemical Society",
journal = "Journal of Natural Products",
title = "Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3726"
}

Stanković, J., Gođevac, D., Tešević, V., Dajić-Stevanović, Z., Ćirić, A. D., Soković, M.,& Novaković, M. M.. (2019). Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970. in Journal of Natural Products
American Chemical Society..
https://hdl.handle.net/21.15107/rcub_cherry_3726

Stanković J, Gođevac D, Tešević V, Dajić-Stevanović Z, Ćirić AD, Soković M, Novaković MM. Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970. in Journal of Natural Products. 2019;.
https://hdl.handle.net/21.15107/rcub_cherry_3726 .

Stanković, Jovana, Gođevac, Dejan, Tešević, Vele, Dajić-Stevanović, Zora, Ćirić, Ana D., Soković, Marina, Novaković, Miroslav M., "Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970" in Journal of Natural Products (2019),
https://hdl.handle.net/21.15107/rcub_cherry_3726 .

TY  - CONF
AU  - Kokalj, Doris
AU  - Gođevac, Dejan
AU  - Anđelković, Boban D.
AU  - Cigić, Blaž
AU  - Zlatić, Emil
AU  - Hribar, Janez
AU  - Vidrih, Rajko
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3736
AB  - A metabolomics approach based on nuclear magnetic resonance (NMR) spectroscopy, a rapid and simple technique, was used for the assessment of chemical changes of 'Van' sweet cherries during their storage. This approach affords a holistic analysis since NMR spectroscopy allows the simultaneous detection of diverse groups of secondary and primary metabolites, and reflects the real molar levels of the metabolites. Additionally, color parameters L∗, a∗ and b∗, total phenolic content (TPC), total flavonoid content (TFC), anthocyanidins and total antioxidant potential (AOP) were measured. After harvest, cherries were stored at 1°C and sampling was done after 0, 2, 4, 7 and 10 days. Cherry skin was removed, freeze dried and stored at -80°C till analyses. For NMR analyses, freeze dried cherry skins have been extracted with methanol-d4/trifluoroacetic acid-d solvent mixture. For other analyses, samples were extracted in 70% ethanol with 1% of formic acid. The 1D and 2D NMR spectral analysis confirmed that sugars (glucose, fructose, sucrose), organic acids (malic and citric acid), and phenolic compounds (neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside) are the main compounds in the cherry skin extracts. The 1H NMR spectral data have been subjected to multivariate analysis. Orthogonal projections to latent structures (OPLS) were applied to correlate the NMR data with the storage time. The changes in chemical composition among the samples with different storage time were clearly visible on the score plot. According to the goodness of fit of the model (R 2 =0.954), and its predictive ability (Q 2 =0.634), cherry skin extracts were well-correlated with the storage time. A positive correlation of the signals corresponding to glucose, neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside with the storage time of cherries has been observed on the loading plot. According to the loading plot, the increase in the content of glucose, neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside has been correlated with the storage time of cherries. Since polyphenolic compounds were found to correlate well with the storage time, the content of redox active compounds was further assessed with AOP, TPC and TFC. All these parameters were increasing for 7 days after harvest then started to decline slightly. The content of all three anthocyanidins increased 2 days after harvest then remained stable till the end of sampling period.
PB  - International Society for Horticultural Science
C3  - Acta Horticulturae
T1  - Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.)
VL  - 1235
SP  - 483
EP  - 488
DO  - 10.17660/ActaHortic.2019.1235.67
ER  - 

@conference{
author = "Kokalj, Doris and Gođevac, Dejan and Anđelković, Boban D. and Cigić, Blaž and Zlatić, Emil and Hribar, Janez and Vidrih, Rajko",
year = "2019",
abstract = "A metabolomics approach based on nuclear magnetic resonance (NMR) spectroscopy, a rapid and simple technique, was used for the assessment of chemical changes of 'Van' sweet cherries during their storage. This approach affords a holistic analysis since NMR spectroscopy allows the simultaneous detection of diverse groups of secondary and primary metabolites, and reflects the real molar levels of the metabolites. Additionally, color parameters L∗, a∗ and b∗, total phenolic content (TPC), total flavonoid content (TFC), anthocyanidins and total antioxidant potential (AOP) were measured. After harvest, cherries were stored at 1°C and sampling was done after 0, 2, 4, 7 and 10 days. Cherry skin was removed, freeze dried and stored at -80°C till analyses. For NMR analyses, freeze dried cherry skins have been extracted with methanol-d4/trifluoroacetic acid-d solvent mixture. For other analyses, samples were extracted in 70% ethanol with 1% of formic acid. The 1D and 2D NMR spectral analysis confirmed that sugars (glucose, fructose, sucrose), organic acids (malic and citric acid), and phenolic compounds (neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside) are the main compounds in the cherry skin extracts. The 1H NMR spectral data have been subjected to multivariate analysis. Orthogonal projections to latent structures (OPLS) were applied to correlate the NMR data with the storage time. The changes in chemical composition among the samples with different storage time were clearly visible on the score plot. According to the goodness of fit of the model (R 2 =0.954), and its predictive ability (Q 2 =0.634), cherry skin extracts were well-correlated with the storage time. A positive correlation of the signals corresponding to glucose, neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside with the storage time of cherries has been observed on the loading plot. According to the loading plot, the increase in the content of glucose, neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside has been correlated with the storage time of cherries. Since polyphenolic compounds were found to correlate well with the storage time, the content of redox active compounds was further assessed with AOP, TPC and TFC. All these parameters were increasing for 7 days after harvest then started to decline slightly. The content of all three anthocyanidins increased 2 days after harvest then remained stable till the end of sampling period.",
publisher = "International Society for Horticultural Science",
journal = "Acta Horticulturae",
title = "Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.)",
volume = "1235",
pages = "483-488",
doi = "10.17660/ActaHortic.2019.1235.67"
}

Kokalj, D., Gođevac, D., Anđelković, B. D., Cigić, B., Zlatić, E., Hribar, J.,& Vidrih, R.. (2019). Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.). in Acta Horticulturae
International Society for Horticultural Science., 1235, 483-488.
https://doi.org/10.17660/ActaHortic.2019.1235.67

Kokalj D, Gođevac D, Anđelković BD, Cigić B, Zlatić E, Hribar J, Vidrih R. Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.). in Acta Horticulturae. 2019;1235:483-488.
doi:10.17660/ActaHortic.2019.1235.67 .

Kokalj, Doris, Gođevac, Dejan, Anđelković, Boban D., Cigić, Blaž, Zlatić, Emil, Hribar, Janez, Vidrih, Rajko, "Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.)" in Acta Horticulturae, 1235 (2019):483-488,
https://doi.org/10.17660/ActaHortic.2019.1235.67 . .

TY  - JOUR
AU  - Novaković, Miroslav M.
AU  - Bukvicki, Danka
AU  - Anđelković, Boban D.
AU  - Ilić-Tomić, Tatjana
AU  - Veljić, Milan
AU  - Tešević, Vele
AU  - Asakawa, Yoshinori
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3096
AB  - Seven new bisbibenzyls (1-7) were isolated from the methanol extract of the liverwort Lunularia cruciata along with one previously known bibenzyl and five known bisbibenzyls. The structures of compounds 1-7 were elucidated on the basis of the spectroscopic data. These newly isolated bisbibenzyls may be divided into two groups, the acyclic bisbibenzyls, perrottetins (1-3), and the cyclic analogues, riccardins (4-7). Besides standard perrottetin and riccardin structures (1 and 4, respectively), they contain phenanthrene (3 and 5), dihydrophenanthrene (2), and quinone moieties (6 and 7), rarely found in natural products. The new compounds 3 and 5, as well as the known riccardin G, exhibited cytotoxic activity against the A549 lung cancer cell line with IC 50 values of 5.0, 5.0, and 2.5 μM, respectively.
PB  - American Chemical Society and American Society of Pharmacognosy
T2  - Journal of Natural Products
T1  - Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata
VL  - 82
IS  - 4
SP  - 694
EP  - 701
DO  - 10.1021/acs.jnatprod.8b00390
ER  - 

@article{
author = "Novaković, Miroslav M. and Bukvicki, Danka and Anđelković, Boban D. and Ilić-Tomić, Tatjana and Veljić, Milan and Tešević, Vele and Asakawa, Yoshinori",
year = "2019",
abstract = "Seven new bisbibenzyls (1-7) were isolated from the methanol extract of the liverwort Lunularia cruciata along with one previously known bibenzyl and five known bisbibenzyls. The structures of compounds 1-7 were elucidated on the basis of the spectroscopic data. These newly isolated bisbibenzyls may be divided into two groups, the acyclic bisbibenzyls, perrottetins (1-3), and the cyclic analogues, riccardins (4-7). Besides standard perrottetin and riccardin structures (1 and 4, respectively), they contain phenanthrene (3 and 5), dihydrophenanthrene (2), and quinone moieties (6 and 7), rarely found in natural products. The new compounds 3 and 5, as well as the known riccardin G, exhibited cytotoxic activity against the A549 lung cancer cell line with IC 50 values of 5.0, 5.0, and 2.5 μM, respectively.",
publisher = "American Chemical Society and American Society of Pharmacognosy",
journal = "Journal of Natural Products",
title = "Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata",
volume = "82",
number = "4",
pages = "694-701",
doi = "10.1021/acs.jnatprod.8b00390"
}

Novaković, M. M., Bukvicki, D., Anđelković, B. D., Ilić-Tomić, T., Veljić, M., Tešević, V.,& Asakawa, Y.. (2019). Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata. in Journal of Natural Products
American Chemical Society and American Society of Pharmacognosy., 82(4), 694-701.
https://doi.org/10.1021/acs.jnatprod.8b00390

Novaković MM, Bukvicki D, Anđelković BD, Ilić-Tomić T, Veljić M, Tešević V, Asakawa Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata. in Journal of Natural Products. 2019;82(4):694-701.
doi:10.1021/acs.jnatprod.8b00390 .

Novaković, Miroslav M., Bukvicki, Danka, Anđelković, Boban D., Ilić-Tomić, Tatjana, Veljić, Milan, Tešević, Vele, Asakawa, Yoshinori, "Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata" in Journal of Natural Products, 82, no. 4 (2019):694-701,
https://doi.org/10.1021/acs.jnatprod.8b00390 . .

TY  - DATA
AU  - Novaković, Miroslav M.
AU  - Bukvicki, Danka
AU  - Anđelković, Boban D.
AU  - Ilić-Tomić, Tatjana
AU  - Veljić, Milan
AU  - Tešević, Vele
AU  - Asakawa, Yoshinori
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3097
PB  - American Chemical Society and American Society of Pharmacognosy
T2  - Journal of Natural Products
T1  - Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390
UR  - https://hdl.handle.net/21.15107/rcub_cherry_3097
ER  - 

@misc{
author = "Novaković, Miroslav M. and Bukvicki, Danka and Anđelković, Boban D. and Ilić-Tomić, Tatjana and Veljić, Milan and Tešević, Vele and Asakawa, Yoshinori",
year = "2019",
publisher = "American Chemical Society and American Society of Pharmacognosy",
journal = "Journal of Natural Products",
title = "Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390",
url = "https://hdl.handle.net/21.15107/rcub_cherry_3097"
}

Novaković, M. M., Bukvicki, D., Anđelković, B. D., Ilić-Tomić, T., Veljić, M., Tešević, V.,& Asakawa, Y.. (2019). Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390. in Journal of Natural Products
American Chemical Society and American Society of Pharmacognosy..
https://hdl.handle.net/21.15107/rcub_cherry_3097

Novaković MM, Bukvicki D, Anđelković BD, Ilić-Tomić T, Veljić M, Tešević V, Asakawa Y. Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390. in Journal of Natural Products. 2019;.
https://hdl.handle.net/21.15107/rcub_cherry_3097 .

Novaković, Miroslav M., Bukvicki, Danka, Anđelković, Boban D., Ilić-Tomić, Tatjana, Veljić, Milan, Tešević, Vele, Asakawa, Yoshinori, "Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390" in Journal of Natural Products (2019),
https://hdl.handle.net/21.15107/rcub_cherry_3097 .

TY  - JOUR
AU  - Gojgić-Cvijović, Gordana D.
AU  - Jakovljević, Dragica M.
AU  - Lončarević, Branka D.
AU  - Todorović, Nevena M.
AU  - Pergal, Marija V.
AU  - Ćirić, J.
AU  - Loos, K.
AU  - Beškoski, Vladimir
AU  - Vrvić, Miroslav M.
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/350
AB  - The production of levan by Bacillus licheniformis NS032 in a medium based on sugar beet molasses was studied. High polysaccharide yields were produced by using diluted molasses (100–140 g/L of total sugars) with the addition of commercial sucrose up to 200 g/L of total sugars, as well as K2HPO4. A levan yield of 53.2 g/L was obtained on a medium optimized by response surface methodology, containing 62.6% of sugar originating from molasses, and 4.66 g/L of phosphate, with initial pH value of 7.2. In comparison to the media with 200 and 400 g/L sucrose, in the molasses optimized medium, the observed bacterial growth was faster, while the maximum production of polysaccharide was achieved over a shorter time interval (48 h). The polysaccharide produced in molasses medium had a weight average molecular weight of 5.82 × 106 Da, degree of branching 12.68%, viscosity of 0.24 dL/g, and based on methylation analysis and NMR data, it did not significantly differ from levan obtained in the medium with 200 g/L sucrose. © 2018 Elsevier B.V.
T2  - International Journal of Biological Macromolecules
T1  - Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium
VL  - 121
SP  - 142
EP  - 151
DO  - 10.1016/j.ijbiomac.2018.10.019
ER  - 

@article{
author = "Gojgić-Cvijović, Gordana D. and Jakovljević, Dragica M. and Lončarević, Branka D. and Todorović, Nevena M. and Pergal, Marija V. and Ćirić, J. and Loos, K. and Beškoski, Vladimir and Vrvić, Miroslav M.",
year = "2019",
abstract = "The production of levan by Bacillus licheniformis NS032 in a medium based on sugar beet molasses was studied. High polysaccharide yields were produced by using diluted molasses (100–140 g/L of total sugars) with the addition of commercial sucrose up to 200 g/L of total sugars, as well as K2HPO4. A levan yield of 53.2 g/L was obtained on a medium optimized by response surface methodology, containing 62.6% of sugar originating from molasses, and 4.66 g/L of phosphate, with initial pH value of 7.2. In comparison to the media with 200 and 400 g/L sucrose, in the molasses optimized medium, the observed bacterial growth was faster, while the maximum production of polysaccharide was achieved over a shorter time interval (48 h). The polysaccharide produced in molasses medium had a weight average molecular weight of 5.82 × 106 Da, degree of branching 12.68%, viscosity of 0.24 dL/g, and based on methylation analysis and NMR data, it did not significantly differ from levan obtained in the medium with 200 g/L sucrose. © 2018 Elsevier B.V.",
journal = "International Journal of Biological Macromolecules",
title = "Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium",
volume = "121",
pages = "142-151",
doi = "10.1016/j.ijbiomac.2018.10.019"
}

Gojgić-Cvijović, G. D., Jakovljević, D. M., Lončarević, B. D., Todorović, N. M., Pergal, M. V., Ćirić, J., Loos, K., Beškoski, V.,& Vrvić, M. M.. (2019). Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium. in International Journal of Biological Macromolecules, 121, 142-151.
https://doi.org/10.1016/j.ijbiomac.2018.10.019

Gojgić-Cvijović GD, Jakovljević DM, Lončarević BD, Todorović NM, Pergal MV, Ćirić J, Loos K, Beškoski V, Vrvić MM. Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium. in International Journal of Biological Macromolecules. 2019;121:142-151.
doi:10.1016/j.ijbiomac.2018.10.019 .

Gojgić-Cvijović, Gordana D., Jakovljević, Dragica M., Lončarević, Branka D., Todorović, Nevena M., Pergal, Marija V., Ćirić, J., Loos, K., Beškoski, Vladimir, Vrvić, Miroslav M., "Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium" in International Journal of Biological Macromolecules, 121 (2019):142-151,
https://doi.org/10.1016/j.ijbiomac.2018.10.019 . .

TY  - JOUR
AU  - Gojgić-Cvijović, Gordana D.
AU  - Jakovljević, Dragica M.
AU  - Lončarević, Branka D.
AU  - Todorović, Nevena M.
AU  - Pergal, Marija V.
AU  - Ćirić, J.
AU  - Loos, K.
AU  - Beškoski, Vladimir
AU  - Vrvić, Miroslav M.
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2799
AB  - The production of levan by Bacillus licheniformis NS032 in a medium based on sugar beet molasses was studied. High polysaccharide yields were produced by using diluted molasses (100–140 g/L of total sugars) with the addition of commercial sucrose up to 200 g/L of total sugars, as well as K2HPO4. A levan yield of 53.2 g/L was obtained on a medium optimized by response surface methodology, containing 62.6% of sugar originating from molasses, and 4.66 g/L of phosphate, with initial pH value of 7.2. In comparison to the media with 200 and 400 g/L sucrose, in the molasses optimized medium, the observed bacterial growth was faster, while the maximum production of polysaccharide was achieved over a shorter time interval (48 h). The polysaccharide produced in molasses medium had a weight average molecular weight of 5.82 × 106 Da, degree of branching 12.68%, viscosity of 0.24 dL/g, and based on methylation analysis and NMR data, it did not significantly differ from levan obtained in the medium with 200 g/L sucrose. © 2018 Elsevier B.V.
T2  - International Journal of Biological Macromolecules
T1  - Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium
VL  - 121
SP  - 142
EP  - 151
DO  - 10.1016/j.ijbiomac.2018.10.019
ER  - 

@article{
author = "Gojgić-Cvijović, Gordana D. and Jakovljević, Dragica M. and Lončarević, Branka D. and Todorović, Nevena M. and Pergal, Marija V. and Ćirić, J. and Loos, K. and Beškoski, Vladimir and Vrvić, Miroslav M.",
year = "2019",
abstract = "The production of levan by Bacillus licheniformis NS032 in a medium based on sugar beet molasses was studied. High polysaccharide yields were produced by using diluted molasses (100–140 g/L of total sugars) with the addition of commercial sucrose up to 200 g/L of total sugars, as well as K2HPO4. A levan yield of 53.2 g/L was obtained on a medium optimized by response surface methodology, containing 62.6% of sugar originating from molasses, and 4.66 g/L of phosphate, with initial pH value of 7.2. In comparison to the media with 200 and 400 g/L sucrose, in the molasses optimized medium, the observed bacterial growth was faster, while the maximum production of polysaccharide was achieved over a shorter time interval (48 h). The polysaccharide produced in molasses medium had a weight average molecular weight of 5.82 × 106 Da, degree of branching 12.68%, viscosity of 0.24 dL/g, and based on methylation analysis and NMR data, it did not significantly differ from levan obtained in the medium with 200 g/L sucrose. © 2018 Elsevier B.V.",
journal = "International Journal of Biological Macromolecules",
title = "Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium",
volume = "121",
pages = "142-151",
doi = "10.1016/j.ijbiomac.2018.10.019"
}

Gojgić-Cvijović, G. D., Jakovljević, D. M., Lončarević, B. D., Todorović, N. M., Pergal, M. V., Ćirić, J., Loos, K., Beškoski, V.,& Vrvić, M. M.. (2019). Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium. in International Journal of Biological Macromolecules, 121, 142-151.
https://doi.org/10.1016/j.ijbiomac.2018.10.019

Gojgić-Cvijović GD, Jakovljević DM, Lončarević BD, Todorović NM, Pergal MV, Ćirić J, Loos K, Beškoski V, Vrvić MM. Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium. in International Journal of Biological Macromolecules. 2019;121:142-151.
doi:10.1016/j.ijbiomac.2018.10.019 .

Gojgić-Cvijović, Gordana D., Jakovljević, Dragica M., Lončarević, Branka D., Todorović, Nevena M., Pergal, Marija V., Ćirić, J., Loos, K., Beškoski, Vladimir, Vrvić, Miroslav M., "Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium" in International Journal of Biological Macromolecules, 121 (2019):142-151,
https://doi.org/10.1016/j.ijbiomac.2018.10.019 . .