TY  - JOUR
AU  - Đorđević, Milena M.
AU  - Jeremić, Dejan
AU  - Rodić, Marko
AU  - Simic, Vera S.
AU  - Brčeski, Ilija
AU  - Leovac, Vukadin M.
PY  - 2014
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1504
AB  - The reaction of an ethanolic solution of the newly synthesized 2-(diphenylphosphino)benzaldehyde 1-adamantoylhydrazone (HL) with aqueous solutions of K-2[MCl4] (M = Pd(II), Pt(II)) resulted in neutral complexes of the general formulae [M(L)Cl]. These complexes have a square-planar structure that was achieved by tridentate PNO coordination of the monoprotonated Schiff base and a chloride ligand. The ligand and its metal complexes were analyzed for their antimicrobial activity and their in vitro cytotoxicity in human larynx carcinoma cells (Hep-2) and non-cancerous human lung fibroblast cells (MRC-5). The platinum(II) complex shows cytotoxicity towards Hep-2 cells comparable to oxaliplatin and exhibited improved selectivity for cancer cells. The ligand and its complexes were characterized by elemental analysis, NMR and IR spectroscopy, and single crystal X-ray diffraction analysis. (C) 2013 Elsevier Ltd. All rights reserved.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Polyhedron
T1  - Synthesis, structure and biological activities of Pd(II) and Pt(II) complexes with 2-(diphenylphosphino)benzaldehyde 1-adamantoylhydrazone
VL  - 68
SP  - 234
EP  - 240
DO  - 10.1016/j.poly.2013.10.029
ER  - 

@article{
author = "Đorđević, Milena M. and Jeremić, Dejan and Rodić, Marko and Simic, Vera S. and Brčeski, Ilija and Leovac, Vukadin M.",
year = "2014",
abstract = "The reaction of an ethanolic solution of the newly synthesized 2-(diphenylphosphino)benzaldehyde 1-adamantoylhydrazone (HL) with aqueous solutions of K-2[MCl4] (M = Pd(II), Pt(II)) resulted in neutral complexes of the general formulae [M(L)Cl]. These complexes have a square-planar structure that was achieved by tridentate PNO coordination of the monoprotonated Schiff base and a chloride ligand. The ligand and its metal complexes were analyzed for their antimicrobial activity and their in vitro cytotoxicity in human larynx carcinoma cells (Hep-2) and non-cancerous human lung fibroblast cells (MRC-5). The platinum(II) complex shows cytotoxicity towards Hep-2 cells comparable to oxaliplatin and exhibited improved selectivity for cancer cells. The ligand and its complexes were characterized by elemental analysis, NMR and IR spectroscopy, and single crystal X-ray diffraction analysis. (C) 2013 Elsevier Ltd. All rights reserved.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Polyhedron",
title = "Synthesis, structure and biological activities of Pd(II) and Pt(II) complexes with 2-(diphenylphosphino)benzaldehyde 1-adamantoylhydrazone",
volume = "68",
pages = "234-240",
doi = "10.1016/j.poly.2013.10.029"
}

Đorđević, M. M., Jeremić, D., Rodić, M., Simic, V. S., Brčeski, I.,& Leovac, V. M.. (2014). Synthesis, structure and biological activities of Pd(II) and Pt(II) complexes with 2-(diphenylphosphino)benzaldehyde 1-adamantoylhydrazone. in Polyhedron
Pergamon-Elsevier Science Ltd, Oxford., 68, 234-240.
https://doi.org/10.1016/j.poly.2013.10.029

Đorđević MM, Jeremić D, Rodić M, Simic VS, Brčeski I, Leovac VM. Synthesis, structure and biological activities of Pd(II) and Pt(II) complexes with 2-(diphenylphosphino)benzaldehyde 1-adamantoylhydrazone. in Polyhedron. 2014;68:234-240.
doi:10.1016/j.poly.2013.10.029 .

Đorđević, Milena M., Jeremić, Dejan, Rodić, Marko, Simic, Vera S., Brčeski, Ilija, Leovac, Vukadin M., "Synthesis, structure and biological activities of Pd(II) and Pt(II) complexes with 2-(diphenylphosphino)benzaldehyde 1-adamantoylhydrazone" in Polyhedron, 68 (2014):234-240,
https://doi.org/10.1016/j.poly.2013.10.029 . .