Natural products of wild, cultivated and edible plants: structure and bioactivity determination

Link to this page

info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS//

Natural products of wild, cultivated and edible plants: structure and bioactivity determination (en)
Биоактивни природни производи самониклих, гајених и јестивих биљака: одређивање структура и активности (sr)
Bioaktivni prirodni proizvodi samoniklih, gajenih i jestivih biljaka: određivanje struktura i aktivnosti (sr_RS)
Authors

Publications

Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts

Vujić, Bojan; Vidaković, Vera; Jadranin, Milka; Novaković, Irena T.; Trifunović, Snežana S.; Tešević, Vele; Mandić, Boris

(MDPI, 2020)

TY  - JOUR
AU  - Vujić, Bojan
AU  - Vidaković, Vera
AU  - Jadranin, Milka
AU  - Novaković, Irena T.
AU  - Trifunović, Snežana S.
AU  - Tešević, Vele
AU  - Mandić, Boris
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3962
AB  - Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.
PB  - MDPI
T2  - Plants
T1  - Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts
VL  - 9
IS  - 3
SP  - 337
DO  - 10.3390/plants9030337
ER  - 
@article{
author = "Vujić, Bojan and Vidaković, Vera and Jadranin, Milka and Novaković, Irena T. and Trifunović, Snežana S. and Tešević, Vele and Mandić, Boris",
year = "2020",
abstract = "Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.",
publisher = "MDPI",
journal = "Plants",
title = "Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts",
volume = "9",
number = "3",
pages = "337",
doi = "10.3390/plants9030337"
}
Vujić, B., Vidaković, V., Jadranin, M., Novaković, I. T., Trifunović, S. S., Tešević, V.,& Mandić, B.. (2020). Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts. in Plants
MDPI., 9(3), 337.
https://doi.org/10.3390/plants9030337
Vujić B, Vidaković V, Jadranin M, Novaković IT, Trifunović SS, Tešević V, Mandić B. Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts. in Plants. 2020;9(3):337.
doi:10.3390/plants9030337 .
Vujić, Bojan, Vidaković, Vera, Jadranin, Milka, Novaković, Irena T., Trifunović, Snežana S., Tešević, Vele, Mandić, Boris, "Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts" in Plants, 9, no. 3 (2020):337,
https://doi.org/10.3390/plants9030337 . .
3
2
2

Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives

Novaković, Miroslav M.; Simić, Stefan; Koračak, Ljiljana; Zlatović, Mario; Ilić-Tomič, Tatjana; Asakawa, Yoshinori; Nikodinović-Runić, Jasmina; Opsenica, Igor

(Elsevier, 2020)

TY  - JOUR
AU  - Novaković, Miroslav M.
AU  - Simić, Stefan
AU  - Koračak, Ljiljana
AU  - Zlatović, Mario
AU  - Ilić-Tomič, Tatjana
AU  - Asakawa, Yoshinori
AU  - Nikodinović-Runić, Jasmina
AU  - Opsenica, Igor
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3867
AB  - Chemical and biocatalytic synthesis of seven previously undescribed marchantin A ester derivatives has been presented. Chemical synthesis afforded three peresterified bisbibenzyl products (TE1-TE3), while enzymatic method, using lipase, produced regioselective monoester derivatives (ME1-ME4). The antiproliferative activities of all prepared derivatives of marchantin A were tested on MRC-5 healthy human lung fibroblast, A549 human lung cancer, and MDA-MB-231 human breast cancer cell lines. All tested esters were less cytotoxic in comparison to marchantin A, but they also exhibited lower cytotoxicity against healthy cells. Monoesters displayed higher cytotoxic activities than the corresponding peresterified products, presumably due to the presence of free catechol group. Monohexanoyl ester ME3 displayed the same IC50 like marchantin A against MDA-MB-231 cells, but the selectivity was higher. In this way, regioselective enzymatic monoesterification enhanced selectivity of marchantin A. ME3 was also the most active among all derivatives against lung cancer cells A549 with the slightly lower activity and selectivity in comparison to marchantin A.
PB  - Elsevier
T2  - Fitoterapia
T1  - Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives
VL  - 142
SP  - 104520
DO  - 10.1016/j.fitote.2020.104520
ER  - 
@article{
author = "Novaković, Miroslav M. and Simić, Stefan and Koračak, Ljiljana and Zlatović, Mario and Ilić-Tomič, Tatjana and Asakawa, Yoshinori and Nikodinović-Runić, Jasmina and Opsenica, Igor",
year = "2020",
abstract = "Chemical and biocatalytic synthesis of seven previously undescribed marchantin A ester derivatives has been presented. Chemical synthesis afforded three peresterified bisbibenzyl products (TE1-TE3), while enzymatic method, using lipase, produced regioselective monoester derivatives (ME1-ME4). The antiproliferative activities of all prepared derivatives of marchantin A were tested on MRC-5 healthy human lung fibroblast, A549 human lung cancer, and MDA-MB-231 human breast cancer cell lines. All tested esters were less cytotoxic in comparison to marchantin A, but they also exhibited lower cytotoxicity against healthy cells. Monoesters displayed higher cytotoxic activities than the corresponding peresterified products, presumably due to the presence of free catechol group. Monohexanoyl ester ME3 displayed the same IC50 like marchantin A against MDA-MB-231 cells, but the selectivity was higher. In this way, regioselective enzymatic monoesterification enhanced selectivity of marchantin A. ME3 was also the most active among all derivatives against lung cancer cells A549 with the slightly lower activity and selectivity in comparison to marchantin A.",
publisher = "Elsevier",
journal = "Fitoterapia",
title = "Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives",
volume = "142",
pages = "104520",
doi = "10.1016/j.fitote.2020.104520"
}
Novaković, M. M., Simić, S., Koračak, L., Zlatović, M., Ilić-Tomič, T., Asakawa, Y., Nikodinović-Runić, J.,& Opsenica, I.. (2020). Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives. in Fitoterapia
Elsevier., 142, 104520.
https://doi.org/10.1016/j.fitote.2020.104520
Novaković MM, Simić S, Koračak L, Zlatović M, Ilić-Tomič T, Asakawa Y, Nikodinović-Runić J, Opsenica I. Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives. in Fitoterapia. 2020;142:104520.
doi:10.1016/j.fitote.2020.104520 .
Novaković, Miroslav M., Simić, Stefan, Koračak, Ljiljana, Zlatović, Mario, Ilić-Tomič, Tatjana, Asakawa, Yoshinori, Nikodinović-Runić, Jasmina, Opsenica, Igor, "Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives" in Fitoterapia, 142 (2020):104520,
https://doi.org/10.1016/j.fitote.2020.104520 . .
1
1
1
1

Supplementary data for the article: Novakovic, M.; Simić, S.; Koračak, L.; Zlatović, M.; Ilic-Tomic, T.; Asakawa, Y.; Nikodinovic-Runic, J.; Opsenica, I. Chemo- and Biocatalytic Esterification of Marchantin A and Cytotoxic Activity of Ester Derivatives. Fitoterapia 2020, 142. https://doi.org/10.1016/j.fitote.2020.104520.oxic activity of ester derivatives http://cherry.chem.bg.ac.rs/handle/123456789/3867

Novaković, Miroslav M.; Simić, Stefan; Koračak, Ljiljana; Zlatović, Mario; Ilić-Tomič, Tatjana; Asakawa, Yoshinori; Nikodinović-Runić, Jasmina; Opsenica, Igor

(Elsevier, 2020)

TY  - DATA
AU  - Novaković, Miroslav M.
AU  - Simić, Stefan
AU  - Koračak, Ljiljana
AU  - Zlatović, Mario
AU  - Ilić-Tomič, Tatjana
AU  - Asakawa, Yoshinori
AU  - Nikodinović-Runić, Jasmina
AU  - Opsenica, Igor
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3889
PB  - Elsevier
T2  - Fitoterapia
T1  - Supplementary data for the article: Novakovic, M.; Simić, S.; Koračak, L.; Zlatović, M.; Ilic-Tomic, T.; Asakawa, Y.; Nikodinovic-Runic, J.; Opsenica, I. Chemo- and Biocatalytic Esterification of Marchantin A and Cytotoxic Activity of Ester Derivatives. Fitoterapia 2020, 142. https://doi.org/10.1016/j.fitote.2020.104520.oxic activity of ester derivatives http://cherry.chem.bg.ac.rs/handle/123456789/3867
ER  - 
@misc{
author = "Novaković, Miroslav M. and Simić, Stefan and Koračak, Ljiljana and Zlatović, Mario and Ilić-Tomič, Tatjana and Asakawa, Yoshinori and Nikodinović-Runić, Jasmina and Opsenica, Igor",
year = "2020",
publisher = "Elsevier",
journal = "Fitoterapia",
title = "Supplementary data for the article: Novakovic, M.; Simić, S.; Koračak, L.; Zlatović, M.; Ilic-Tomic, T.; Asakawa, Y.; Nikodinovic-Runic, J.; Opsenica, I. Chemo- and Biocatalytic Esterification of Marchantin A and Cytotoxic Activity of Ester Derivatives. Fitoterapia 2020, 142. https://doi.org/10.1016/j.fitote.2020.104520.oxic activity of ester derivatives http://cherry.chem.bg.ac.rs/handle/123456789/3867"
}
Novaković, M. M., Simić, S., Koračak, L., Zlatović, M., Ilić-Tomič, T., Asakawa, Y., Nikodinović-Runić, J.,& Opsenica, I.. (2020). Supplementary data for the article: Novakovic, M.; Simić, S.; Koračak, L.; Zlatović, M.; Ilic-Tomic, T.; Asakawa, Y.; Nikodinovic-Runic, J.; Opsenica, I. Chemo- and Biocatalytic Esterification of Marchantin A and Cytotoxic Activity of Ester Derivatives. Fitoterapia 2020, 142. https://doi.org/10.1016/j.fitote.2020.104520.oxic activity of ester derivatives http://cherry.chem.bg.ac.rs/handle/123456789/3867. in Fitoterapia
Elsevier..
Novaković MM, Simić S, Koračak L, Zlatović M, Ilić-Tomič T, Asakawa Y, Nikodinović-Runić J, Opsenica I. Supplementary data for the article: Novakovic, M.; Simić, S.; Koračak, L.; Zlatović, M.; Ilic-Tomic, T.; Asakawa, Y.; Nikodinovic-Runic, J.; Opsenica, I. Chemo- and Biocatalytic Esterification of Marchantin A and Cytotoxic Activity of Ester Derivatives. Fitoterapia 2020, 142. https://doi.org/10.1016/j.fitote.2020.104520.oxic activity of ester derivatives http://cherry.chem.bg.ac.rs/handle/123456789/3867. in Fitoterapia. 2020;..
Novaković, Miroslav M., Simić, Stefan, Koračak, Ljiljana, Zlatović, Mario, Ilić-Tomič, Tatjana, Asakawa, Yoshinori, Nikodinović-Runić, Jasmina, Opsenica, Igor, "Supplementary data for the article: Novakovic, M.; Simić, S.; Koračak, L.; Zlatović, M.; Ilic-Tomic, T.; Asakawa, Y.; Nikodinovic-Runic, J.; Opsenica, I. Chemo- and Biocatalytic Esterification of Marchantin A and Cytotoxic Activity of Ester Derivatives. Fitoterapia 2020, 142. https://doi.org/10.1016/j.fitote.2020.104520.oxic activity of ester derivatives http://cherry.chem.bg.ac.rs/handle/123456789/3867" in Fitoterapia (2020).

Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives

Novaković, Miroslav M.; Simić, Stefan; Koračak, Ljiljana; Zlatović, Mario; Ilić-Tomič, Tatjana; Asakawa, Yoshinori; Nikodinović-Runić, Jasmina; Opsenica, Igor

(Elsevier, 2020)

TY  - JOUR
AU  - Novaković, Miroslav M.
AU  - Simić, Stefan
AU  - Koračak, Ljiljana
AU  - Zlatović, Mario
AU  - Ilić-Tomič, Tatjana
AU  - Asakawa, Yoshinori
AU  - Nikodinović-Runić, Jasmina
AU  - Opsenica, Igor
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3890
AB  - Chemical and biocatalytic synthesis of seven previously undescribed marchantin A ester derivatives has been presented. Chemical synthesis afforded three peresterified bisbibenzyl products (TE1-TE3), while enzymatic method, using lipase, produced regioselective monoester derivatives (ME1-ME4). The antiproliferative activities of all prepared derivatives of marchantin A were tested on MRC-5 healthy human lung fibroblast, A549 human lung cancer, and MDA-MB-231 human breast cancer cell lines. All tested esters were less cytotoxic in comparison to marchantin A, but they also exhibited lower cytotoxicity against healthy cells. Monoesters displayed higher cytotoxic activities than the corresponding peresterified products, presumably due to the presence of free catechol group. Monohexanoyl ester ME3 displayed the same IC50 like marchantin A against MDA-MB-231 cells, but the selectivity was higher. In this way, regioselective enzymatic monoesterification enhanced selectivity of marchantin A. ME3 was also the most active among all derivatives against lung cancer cells A549 with the slightly lower activity and selectivity in comparison to marchantin A.
PB  - Elsevier
T2  - Fitoterapia
T1  - Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives
VL  - 142
SP  - 104520
DO  - 10.1016/j.fitote.2020.104520
ER  - 
@article{
author = "Novaković, Miroslav M. and Simić, Stefan and Koračak, Ljiljana and Zlatović, Mario and Ilić-Tomič, Tatjana and Asakawa, Yoshinori and Nikodinović-Runić, Jasmina and Opsenica, Igor",
year = "2020",
abstract = "Chemical and biocatalytic synthesis of seven previously undescribed marchantin A ester derivatives has been presented. Chemical synthesis afforded three peresterified bisbibenzyl products (TE1-TE3), while enzymatic method, using lipase, produced regioselective monoester derivatives (ME1-ME4). The antiproliferative activities of all prepared derivatives of marchantin A were tested on MRC-5 healthy human lung fibroblast, A549 human lung cancer, and MDA-MB-231 human breast cancer cell lines. All tested esters were less cytotoxic in comparison to marchantin A, but they also exhibited lower cytotoxicity against healthy cells. Monoesters displayed higher cytotoxic activities than the corresponding peresterified products, presumably due to the presence of free catechol group. Monohexanoyl ester ME3 displayed the same IC50 like marchantin A against MDA-MB-231 cells, but the selectivity was higher. In this way, regioselective enzymatic monoesterification enhanced selectivity of marchantin A. ME3 was also the most active among all derivatives against lung cancer cells A549 with the slightly lower activity and selectivity in comparison to marchantin A.",
publisher = "Elsevier",
journal = "Fitoterapia",
title = "Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives",
volume = "142",
pages = "104520",
doi = "10.1016/j.fitote.2020.104520"
}
Novaković, M. M., Simić, S., Koračak, L., Zlatović, M., Ilić-Tomič, T., Asakawa, Y., Nikodinović-Runić, J.,& Opsenica, I.. (2020). Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives. in Fitoterapia
Elsevier., 142, 104520.
https://doi.org/10.1016/j.fitote.2020.104520
Novaković MM, Simić S, Koračak L, Zlatović M, Ilić-Tomič T, Asakawa Y, Nikodinović-Runić J, Opsenica I. Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives. in Fitoterapia. 2020;142:104520.
doi:10.1016/j.fitote.2020.104520 .
Novaković, Miroslav M., Simić, Stefan, Koračak, Ljiljana, Zlatović, Mario, Ilić-Tomič, Tatjana, Asakawa, Yoshinori, Nikodinović-Runić, Jasmina, Opsenica, Igor, "Chemo- and biocatalytic esterification of marchantin A and cytotoxic activity of ester derivatives" in Fitoterapia, 142 (2020):104520,
https://doi.org/10.1016/j.fitote.2020.104520 . .
1
1
1
1

Bisaurones – enzymatic production and biological evaluation

Novaković, Miroslav M.; Ilić-Tomić, Tatjana; Tešević, Vele; Simić, Katarina; Ivanović, Stefan; Simić, Stefan; Opsenica, Igor; Nikodinović-Runić, Jasmina

(Royal Society of Chemistry, 2020)

TY  - JOUR
AU  - Novaković, Miroslav M.
AU  - Ilić-Tomić, Tatjana
AU  - Tešević, Vele
AU  - Simić, Katarina
AU  - Ivanović, Stefan
AU  - Simić, Stefan
AU  - Opsenica, Igor
AU  - Nikodinović-Runić, Jasmina
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4052
AB  - The Trametes versicolor laccase catalyzed oxidation of chalcone butein afforded four dimers of aurone sulfuretin (i.e. two regioisomeric pairs of diasteromers, 1-4) as the major products. The formation of the dimers was explained by a two step process involving the initial cyclization of butein into aurone sulfuretin, followed by the combination of two molecules of sulfuretin. The coupling process occurred between the 2,10-double bond of one molecule of sulfuretin and the (3′,4′) catechol group of the other to yield a dimeric structure. This was confirmed by the experiment involving the laccase catalyzed oxidation of sulfuretin yielding the same dimeric bisaurones. Compounds 1, 3 and 4, were isolated using semipreparative HPLC and characterized by the detailed analysis of the NMR, MS, IR, and UV-vis data. The structure of compound 2, isolated as a mixture containing ca. 25% of compound 1, was proposed by the comparison of 1H NMR data to compound 1 and by using LC-ESIMS analysis. The starting chalcone butein and the products of the biocatalytic transformation, aurone sulfuretin and sulfuretin dimers 1, 3 and 4, were evaluated for their cytotoxic and antioxidative properties in vitro using a healthy human fibroblast (MRC5) cell line. The biotransformation products showed lower cytotoxicity but higher antioxidative properties. The C. coggygria bark methanol extract rich in butein and sulfuretin was also biotransformed by laccase. The transformed extract exhibited significantly improved antioxidative activities.
PB  - Royal Society of Chemistry
T2  - New Journal of Chemistry
T1  - Bisaurones – enzymatic production and biological evaluation
VL  - 44
IS  - 23
SP  - 9647
EP  - 9655
DO  - 10.1039/d0nj00758g
ER  - 
@article{
author = "Novaković, Miroslav M. and Ilić-Tomić, Tatjana and Tešević, Vele and Simić, Katarina and Ivanović, Stefan and Simić, Stefan and Opsenica, Igor and Nikodinović-Runić, Jasmina",
year = "2020",
abstract = "The Trametes versicolor laccase catalyzed oxidation of chalcone butein afforded four dimers of aurone sulfuretin (i.e. two regioisomeric pairs of diasteromers, 1-4) as the major products. The formation of the dimers was explained by a two step process involving the initial cyclization of butein into aurone sulfuretin, followed by the combination of two molecules of sulfuretin. The coupling process occurred between the 2,10-double bond of one molecule of sulfuretin and the (3′,4′) catechol group of the other to yield a dimeric structure. This was confirmed by the experiment involving the laccase catalyzed oxidation of sulfuretin yielding the same dimeric bisaurones. Compounds 1, 3 and 4, were isolated using semipreparative HPLC and characterized by the detailed analysis of the NMR, MS, IR, and UV-vis data. The structure of compound 2, isolated as a mixture containing ca. 25% of compound 1, was proposed by the comparison of 1H NMR data to compound 1 and by using LC-ESIMS analysis. The starting chalcone butein and the products of the biocatalytic transformation, aurone sulfuretin and sulfuretin dimers 1, 3 and 4, were evaluated for their cytotoxic and antioxidative properties in vitro using a healthy human fibroblast (MRC5) cell line. The biotransformation products showed lower cytotoxicity but higher antioxidative properties. The C. coggygria bark methanol extract rich in butein and sulfuretin was also biotransformed by laccase. The transformed extract exhibited significantly improved antioxidative activities.",
publisher = "Royal Society of Chemistry",
journal = "New Journal of Chemistry",
title = "Bisaurones – enzymatic production and biological evaluation",
volume = "44",
number = "23",
pages = "9647-9655",
doi = "10.1039/d0nj00758g"
}
Novaković, M. M., Ilić-Tomić, T., Tešević, V., Simić, K., Ivanović, S., Simić, S., Opsenica, I.,& Nikodinović-Runić, J.. (2020). Bisaurones – enzymatic production and biological evaluation. in New Journal of Chemistry
Royal Society of Chemistry., 44(23), 9647-9655.
https://doi.org/10.1039/d0nj00758g
Novaković MM, Ilić-Tomić T, Tešević V, Simić K, Ivanović S, Simić S, Opsenica I, Nikodinović-Runić J. Bisaurones – enzymatic production and biological evaluation. in New Journal of Chemistry. 2020;44(23):9647-9655.
doi:10.1039/d0nj00758g .
Novaković, Miroslav M., Ilić-Tomić, Tatjana, Tešević, Vele, Simić, Katarina, Ivanović, Stefan, Simić, Stefan, Opsenica, Igor, Nikodinović-Runić, Jasmina, "Bisaurones – enzymatic production and biological evaluation" in New Journal of Chemistry, 44, no. 23 (2020):9647-9655,
https://doi.org/10.1039/d0nj00758g . .

Supplementary data for the article: Novakovic, M.; Ilic-Tomic, T.; Tesevic, V.; Simic, K.; Ivanovic, S.; Simic, S.; Opsenica, I.; Nikodinovic-Runic, J. Bisaurones – Enzymatic Production and Biological Evaluation. New J. Chem. 2020, 44 (23), 9647–9655. https://doi.org/10.1039/D0NJ00758G

Novaković, Miroslav M.; Ilić-Tomić, Tatjana; Tešević, Vele; Simić, Katarina; Ivanović, Stefan; Simić, Stefan; Opsenica, Igor; Nikodinović-Runić, Jasmina

(Royal Society of Chemistry, 2020)

TY  - DATA
AU  - Novaković, Miroslav M.
AU  - Ilić-Tomić, Tatjana
AU  - Tešević, Vele
AU  - Simić, Katarina
AU  - Ivanović, Stefan
AU  - Simić, Stefan
AU  - Opsenica, Igor
AU  - Nikodinović-Runić, Jasmina
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4078
PB  - Royal Society of Chemistry
T2  - New Journal of Chemistry
T1  - Supplementary data for the article: Novakovic, M.; Ilic-Tomic, T.; Tesevic, V.; Simic, K.; Ivanovic, S.; Simic, S.; Opsenica, I.; Nikodinovic-Runic, J. Bisaurones – Enzymatic Production and Biological Evaluation. New J. Chem. 2020, 44 (23), 9647–9655. https://doi.org/10.1039/D0NJ00758G
ER  - 
@misc{
author = "Novaković, Miroslav M. and Ilić-Tomić, Tatjana and Tešević, Vele and Simić, Katarina and Ivanović, Stefan and Simić, Stefan and Opsenica, Igor and Nikodinović-Runić, Jasmina",
year = "2020",
publisher = "Royal Society of Chemistry",
journal = "New Journal of Chemistry",
title = "Supplementary data for the article: Novakovic, M.; Ilic-Tomic, T.; Tesevic, V.; Simic, K.; Ivanovic, S.; Simic, S.; Opsenica, I.; Nikodinovic-Runic, J. Bisaurones – Enzymatic Production and Biological Evaluation. New J. Chem. 2020, 44 (23), 9647–9655. https://doi.org/10.1039/D0NJ00758G"
}
Novaković, M. M., Ilić-Tomić, T., Tešević, V., Simić, K., Ivanović, S., Simić, S., Opsenica, I.,& Nikodinović-Runić, J.. (2020). Supplementary data for the article: Novakovic, M.; Ilic-Tomic, T.; Tesevic, V.; Simic, K.; Ivanovic, S.; Simic, S.; Opsenica, I.; Nikodinovic-Runic, J. Bisaurones – Enzymatic Production and Biological Evaluation. New J. Chem. 2020, 44 (23), 9647–9655. https://doi.org/10.1039/D0NJ00758G. in New Journal of Chemistry
Royal Society of Chemistry..
Novaković MM, Ilić-Tomić T, Tešević V, Simić K, Ivanović S, Simić S, Opsenica I, Nikodinović-Runić J. Supplementary data for the article: Novakovic, M.; Ilic-Tomic, T.; Tesevic, V.; Simic, K.; Ivanovic, S.; Simic, S.; Opsenica, I.; Nikodinovic-Runic, J. Bisaurones – Enzymatic Production and Biological Evaluation. New J. Chem. 2020, 44 (23), 9647–9655. https://doi.org/10.1039/D0NJ00758G. in New Journal of Chemistry. 2020;..
Novaković, Miroslav M., Ilić-Tomić, Tatjana, Tešević, Vele, Simić, Katarina, Ivanović, Stefan, Simić, Stefan, Opsenica, Igor, Nikodinović-Runić, Jasmina, "Supplementary data for the article: Novakovic, M.; Ilic-Tomic, T.; Tesevic, V.; Simic, K.; Ivanovic, S.; Simic, S.; Opsenica, I.; Nikodinovic-Runic, J. Bisaurones – Enzymatic Production and Biological Evaluation. New J. Chem. 2020, 44 (23), 9647–9655. https://doi.org/10.1039/D0NJ00758G" in New Journal of Chemistry (2020).

Integration of dry-column flash chromatography with NMR and FTIR metabolomics to reveal cytotoxic metabolites from Amphoricarpos autariatus

Cvetković, Mirjana; Damjanović, Ana; Stanojković, Tatjana; Đorđević, Iris; Tešević, Vele; Milosavljević, Slobodan M.; Gođevac, Dejan

(2020)

TY  - JOUR
AU  - Cvetković, Mirjana
AU  - Damjanović, Ana
AU  - Stanojković, Tatjana
AU  - Đorđević, Iris
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan M.
AU  - Gođevac, Dejan
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3348
AB  - Metabolomics generate a profile of small molecules from plant extracts, which could be directly responsible for bioactivity effects. Using dry-column flash chromatography enabled a rapid and inexpensive method for the very efficient separation of plant extract with a high resolution. This separation method coupled to NMR and FTIR-based metabolomics is applied to identify bioactive natural products. OPLS multivariate analysis method, was used for correlation the chemical composition of the plant extracts, Amphoricarpos autariatus, with the results of cytotoxic activity against Human cervical adenocarcinoma cell line (HeLa) and epithelial lung cancer cell line (A549). In this way, the highest contribution to the cytotoxic activity was recorded for the guaianolide sesquiterpene lactones named amphoricarpolides. The compounds indicated as bioactive after metabolomics analysis were tested, and their cytotoxic activity were confirmed.
T2  - Talanta
T1  - Integration of dry-column flash chromatography with NMR and FTIR metabolomics to reveal cytotoxic metabolites from Amphoricarpos autariatus
VL  - 206
SP  - 1
EP  - 6
DO  - 10.1016/j.talanta.2019.120248
ER  - 
@article{
author = "Cvetković, Mirjana and Damjanović, Ana and Stanojković, Tatjana and Đorđević, Iris and Tešević, Vele and Milosavljević, Slobodan M. and Gođevac, Dejan",
year = "2020",
abstract = "Metabolomics generate a profile of small molecules from plant extracts, which could be directly responsible for bioactivity effects. Using dry-column flash chromatography enabled a rapid and inexpensive method for the very efficient separation of plant extract with a high resolution. This separation method coupled to NMR and FTIR-based metabolomics is applied to identify bioactive natural products. OPLS multivariate analysis method, was used for correlation the chemical composition of the plant extracts, Amphoricarpos autariatus, with the results of cytotoxic activity against Human cervical adenocarcinoma cell line (HeLa) and epithelial lung cancer cell line (A549). In this way, the highest contribution to the cytotoxic activity was recorded for the guaianolide sesquiterpene lactones named amphoricarpolides. The compounds indicated as bioactive after metabolomics analysis were tested, and their cytotoxic activity were confirmed.",
journal = "Talanta",
title = "Integration of dry-column flash chromatography with NMR and FTIR metabolomics to reveal cytotoxic metabolites from Amphoricarpos autariatus",
volume = "206",
pages = "1-6",
doi = "10.1016/j.talanta.2019.120248"
}
Cvetković, M., Damjanović, A., Stanojković, T., Đorđević, I., Tešević, V., Milosavljević, S. M.,& Gođevac, D.. (2020). Integration of dry-column flash chromatography with NMR and FTIR metabolomics to reveal cytotoxic metabolites from Amphoricarpos autariatus. in Talanta, 206, 1-6.
https://doi.org/10.1016/j.talanta.2019.120248
Cvetković M, Damjanović A, Stanojković T, Đorđević I, Tešević V, Milosavljević SM, Gođevac D. Integration of dry-column flash chromatography with NMR and FTIR metabolomics to reveal cytotoxic metabolites from Amphoricarpos autariatus. in Talanta. 2020;206:1-6.
doi:10.1016/j.talanta.2019.120248 .
Cvetković, Mirjana, Damjanović, Ana, Stanojković, Tatjana, Đorđević, Iris, Tešević, Vele, Milosavljević, Slobodan M., Gođevac, Dejan, "Integration of dry-column flash chromatography with NMR and FTIR metabolomics to reveal cytotoxic metabolites from Amphoricarpos autariatus" in Talanta, 206 (2020):1-6,
https://doi.org/10.1016/j.talanta.2019.120248 . .
2
1
1

Supplementary material for the article: Cvetković, M.; Damjanović, A.; Stanojković, T. P.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. Integration of Dry-Column Flash Chromatography with NMR and FTIR Metabolomics to Reveal Cytotoxic Metabolites from Amphoricarpos Autariatus. Talanta 2020, 206. https://doi.org/10.1016/j.talanta.2019.120248

Cvetković, Mirjana; Damjanović, Ana; Stanojković, Tatjana; Đorđević, Iris; Tešević, Vele; Milosavljević, Slobodan M.; Gođevac, Dejan

(2020)

TY  - DATA
AU  - Cvetković, Mirjana
AU  - Damjanović, Ana
AU  - Stanojković, Tatjana
AU  - Đorđević, Iris
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan M.
AU  - Gođevac, Dejan
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3349
T2  - Talanta
T1  - Supplementary material for the article: Cvetković, M.; Damjanović, A.; Stanojković, T. P.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. Integration of Dry-Column Flash Chromatography with NMR and FTIR Metabolomics to Reveal Cytotoxic Metabolites from Amphoricarpos Autariatus. Talanta 2020, 206. https://doi.org/10.1016/j.talanta.2019.120248
ER  - 
@misc{
author = "Cvetković, Mirjana and Damjanović, Ana and Stanojković, Tatjana and Đorđević, Iris and Tešević, Vele and Milosavljević, Slobodan M. and Gođevac, Dejan",
year = "2020",
journal = "Talanta",
title = "Supplementary material for the article: Cvetković, M.; Damjanović, A.; Stanojković, T. P.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. Integration of Dry-Column Flash Chromatography with NMR and FTIR Metabolomics to Reveal Cytotoxic Metabolites from Amphoricarpos Autariatus. Talanta 2020, 206. https://doi.org/10.1016/j.talanta.2019.120248"
}
Cvetković, M., Damjanović, A., Stanojković, T., Đorđević, I., Tešević, V., Milosavljević, S. M.,& Gođevac, D.. (2020). Supplementary material for the article: Cvetković, M.; Damjanović, A.; Stanojković, T. P.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. Integration of Dry-Column Flash Chromatography with NMR and FTIR Metabolomics to Reveal Cytotoxic Metabolites from Amphoricarpos Autariatus. Talanta 2020, 206. https://doi.org/10.1016/j.talanta.2019.120248. in Talanta.
Cvetković M, Damjanović A, Stanojković T, Đorđević I, Tešević V, Milosavljević SM, Gođevac D. Supplementary material for the article: Cvetković, M.; Damjanović, A.; Stanojković, T. P.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. Integration of Dry-Column Flash Chromatography with NMR and FTIR Metabolomics to Reveal Cytotoxic Metabolites from Amphoricarpos Autariatus. Talanta 2020, 206. https://doi.org/10.1016/j.talanta.2019.120248. in Talanta. 2020;..
Cvetković, Mirjana, Damjanović, Ana, Stanojković, Tatjana, Đorđević, Iris, Tešević, Vele, Milosavljević, Slobodan M., Gođevac, Dejan, "Supplementary material for the article: Cvetković, M.; Damjanović, A.; Stanojković, T. P.; Đorđević, I.; Tešević, V.; Milosavljević, S.; Gođevac, D. Integration of Dry-Column Flash Chromatography with NMR and FTIR Metabolomics to Reveal Cytotoxic Metabolites from Amphoricarpos Autariatus. Talanta 2020, 206. https://doi.org/10.1016/j.talanta.2019.120248" in Talanta (2020).

Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster

Nikolić, Biljana; Todosijević, Marina; Đorđević, Iris; Stanković, Jovana; Mitić, Zorica S.; Tešević, Vele; Marin, Petar D.

(SAGE Publishing, 2020)

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Todosijević, Marina
AU  - Đorđević, Iris
AU  - Stanković, Jovana
AU  - Mitić, Zorica S.
AU  - Tešević, Vele
AU  - Marin, Petar D.
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4237
AB  - In leaf cuticular wax of Pinus pinaster, content of nonacosan-10-ol is high (77.1% on average). n-Alkanes ranged from C18 to C35 with the most dominant C29 (24.8%). The carbon preference index (CPItotal) ranged from 3.1 to 5.6 (4.0 on average), while the average chain length (ACLtotal) ranged from 14.0 to 17.0 (14.8 on average). Long-chain n-alkanes (n-C25-35) strongly dominated (80.1%) over middle-chain (n-C21-24= 18.9%) and short-chain (n-C18-20= 0.9%) n-alkanes.
PB  - SAGE Publishing
T2  - Natural Product Communications
T1  - Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster
VL  - 15
IS  - 5
DO  - 10.1177/1934578X20926073
ER  - 
@article{
author = "Nikolić, Biljana and Todosijević, Marina and Đorđević, Iris and Stanković, Jovana and Mitić, Zorica S. and Tešević, Vele and Marin, Petar D.",
year = "2020",
abstract = "In leaf cuticular wax of Pinus pinaster, content of nonacosan-10-ol is high (77.1% on average). n-Alkanes ranged from C18 to C35 with the most dominant C29 (24.8%). The carbon preference index (CPItotal) ranged from 3.1 to 5.6 (4.0 on average), while the average chain length (ACLtotal) ranged from 14.0 to 17.0 (14.8 on average). Long-chain n-alkanes (n-C25-35) strongly dominated (80.1%) over middle-chain (n-C21-24= 18.9%) and short-chain (n-C18-20= 0.9%) n-alkanes.",
publisher = "SAGE Publishing",
journal = "Natural Product Communications",
title = "Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster",
volume = "15",
number = "5",
doi = "10.1177/1934578X20926073"
}
Nikolić, B., Todosijević, M., Đorđević, I., Stanković, J., Mitić, Z. S., Tešević, V.,& Marin, P. D.. (2020). Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster. in Natural Product Communications
SAGE Publishing., 15(5).
https://doi.org/10.1177/1934578X20926073
Nikolić B, Todosijević M, Đorđević I, Stanković J, Mitić ZS, Tešević V, Marin PD. Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster. in Natural Product Communications. 2020;15(5).
doi:10.1177/1934578X20926073 .
Nikolić, Biljana, Todosijević, Marina, Đorđević, Iris, Stanković, Jovana, Mitić, Zorica S., Tešević, Vele, Marin, Petar D., "Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster" in Natural Product Communications, 15, no. 5 (2020),
https://doi.org/10.1177/1934578X20926073 . .

Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species

Vesović, Nikola; Ćurčić, Srećko; Todosijević, Marina; Nenadić, Marija; Zhang, Wang; Vujisić, Ljubodrag V.

(Springer, 2020)

TY  - JOUR
AU  - Vesović, Nikola
AU  - Ćurčić, Srećko
AU  - Todosijević, Marina
AU  - Nenadić, Marija
AU  - Zhang, Wang
AU  - Vujisić, Ljubodrag V.
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3972
AB  - It is a commonly known fact that all ground beetles possess abdominal pygidial glands with relatively similar gross structure and function among species. Still, morphology of the glands and composition of their secretions have not been studied in most ground beetle species. These exocrine glands and their products are mainly associated with defence in natural environments. In this paper, we studied three predatory ground beetle species of the genus Carabus Linnaeus, 1758, namely C. (Archicarabus) montivagus Palliardi, 1825, C. (Megodontus) caelatus Fabricius, 1801, and C. (M.) violaceus Linnaeus, 1758, to identify chemical components of their pygidial gland secretions. Altogether, 10 carboxylic acids were isolated from the analysed secretions [two from the secretion of C. (A.) montivagus, 10 from that of C. (M.) caelatus, and nine from that of C. (M.) violaceus]. The finding of 2-hexenoic acid in the secretion of C. (M.) caelatus is the first finding of it within the entire subfamily Carabinae. In addition, we also analysed the morphology of glands of the species C. (M.) violaceus.
PB  - Springer
T2  - Chemoecology
T1  - Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species
VL  - 30
IS  - 2
SP  - 59
EP  - 68
DO  - 10.1007/s00049-019-00298-w
ER  - 
@article{
author = "Vesović, Nikola and Ćurčić, Srećko and Todosijević, Marina and Nenadić, Marija and Zhang, Wang and Vujisić, Ljubodrag V.",
year = "2020",
abstract = "It is a commonly known fact that all ground beetles possess abdominal pygidial glands with relatively similar gross structure and function among species. Still, morphology of the glands and composition of their secretions have not been studied in most ground beetle species. These exocrine glands and their products are mainly associated with defence in natural environments. In this paper, we studied three predatory ground beetle species of the genus Carabus Linnaeus, 1758, namely C. (Archicarabus) montivagus Palliardi, 1825, C. (Megodontus) caelatus Fabricius, 1801, and C. (M.) violaceus Linnaeus, 1758, to identify chemical components of their pygidial gland secretions. Altogether, 10 carboxylic acids were isolated from the analysed secretions [two from the secretion of C. (A.) montivagus, 10 from that of C. (M.) caelatus, and nine from that of C. (M.) violaceus]. The finding of 2-hexenoic acid in the secretion of C. (M.) caelatus is the first finding of it within the entire subfamily Carabinae. In addition, we also analysed the morphology of glands of the species C. (M.) violaceus.",
publisher = "Springer",
journal = "Chemoecology",
title = "Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species",
volume = "30",
number = "2",
pages = "59-68",
doi = "10.1007/s00049-019-00298-w"
}
Vesović, N., Ćurčić, S., Todosijević, M., Nenadić, M., Zhang, W.,& Vujisić, L. V.. (2020). Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species. in Chemoecology
Springer., 30(2), 59-68.
https://doi.org/10.1007/s00049-019-00298-w
Vesović N, Ćurčić S, Todosijević M, Nenadić M, Zhang W, Vujisić LV. Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species. in Chemoecology. 2020;30(2):59-68.
doi:10.1007/s00049-019-00298-w .
Vesović, Nikola, Ćurčić, Srećko, Todosijević, Marina, Nenadić, Marija, Zhang, Wang, Vujisić, Ljubodrag V., "Pygidial gland secretions of Carabus Linnaeus, 1758 (Coleoptera: Carabidae): chemicals released by three species" in Chemoecology, 30, no. 2 (2020):59-68,
https://doi.org/10.1007/s00049-019-00298-w . .
3
2
3

Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae)

Vranić, Sofija; Ćurčić, Srećko; Vesović, Nikola; Mandić, Boris; Pantelić, Dejan; Vasović, Marija; Lazović, Vladimir; Zhang, Wang; Vujisić, Ljubodrag V.

(Elsevier, 2020)

TY  - JOUR
AU  - Vranić, Sofija
AU  - Ćurčić, Srećko
AU  - Vesović, Nikola
AU  - Mandić, Boris
AU  - Pantelić, Dejan
AU  - Vasović, Marija
AU  - Lazović, Vladimir
AU  - Zhang, Wang
AU  - Vujisić, Ljubodrag V.
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4240
AB  - Morphology of the pygidial glands and chemical composition of their secretions in adults of four ground beetle representatives of the Pterostichini tribe (Coleoptera: Carabidae) were analysed. Molops (Stenochoromus) montenegrinus, Pterostichus (Cophosus) cylindricus, P. (Feronidius) melas and P. (Pseudomaseus) nigrita were chemically tested, while the latter three species were morphologically investigated. Pterostichus (C.) cylindricus, P. (P.) nigrita and M. (S.) montenegrinus were chemically studied for the first time. Altogether, 23 chemical compounds were isolated using gas chromatography-mass spectrometry (GC-MS), of which some are new for Pterostichini or even Carabidae. Methacrylic acid was present in all species analysed. It was predominant in the secretion extract of P. (C.) cylindricus and P. (F.) melas. Isobutyric and 2-methylbutyric acids were the major components in the secretion of M. (S.) montenegrinus. Undecane, methacrylic and tiglic acids were the main components in the secretion of P. (P.) nigrita. The simplest chemical mixture was found in P. (C.) cylindricus (two compounds), while the most complex one was detected in P. (P.) nigrita (15 compounds). No significant differences in the chemical composition of the pygidial gland secretions were evidenced in P. (C.) cylindricus sampled from the same area and in the same season in two different years. Morphology of the pygidial glands of the studied species was analysed for the first time. Morphological features of the pygidial glands were observed using bright-field microscopy and nonlinear microscopy and described in details.
PB  - Elsevier
T2  - Zoology
T1  - Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae)
VL  - 142
SP  - 125772
DO  - 10.1016/j.zool.2020.125772
ER  - 
@article{
author = "Vranić, Sofija and Ćurčić, Srećko and Vesović, Nikola and Mandić, Boris and Pantelić, Dejan and Vasović, Marija and Lazović, Vladimir and Zhang, Wang and Vujisić, Ljubodrag V.",
year = "2020",
abstract = "Morphology of the pygidial glands and chemical composition of their secretions in adults of four ground beetle representatives of the Pterostichini tribe (Coleoptera: Carabidae) were analysed. Molops (Stenochoromus) montenegrinus, Pterostichus (Cophosus) cylindricus, P. (Feronidius) melas and P. (Pseudomaseus) nigrita were chemically tested, while the latter three species were morphologically investigated. Pterostichus (C.) cylindricus, P. (P.) nigrita and M. (S.) montenegrinus were chemically studied for the first time. Altogether, 23 chemical compounds were isolated using gas chromatography-mass spectrometry (GC-MS), of which some are new for Pterostichini or even Carabidae. Methacrylic acid was present in all species analysed. It was predominant in the secretion extract of P. (C.) cylindricus and P. (F.) melas. Isobutyric and 2-methylbutyric acids were the major components in the secretion of M. (S.) montenegrinus. Undecane, methacrylic and tiglic acids were the main components in the secretion of P. (P.) nigrita. The simplest chemical mixture was found in P. (C.) cylindricus (two compounds), while the most complex one was detected in P. (P.) nigrita (15 compounds). No significant differences in the chemical composition of the pygidial gland secretions were evidenced in P. (C.) cylindricus sampled from the same area and in the same season in two different years. Morphology of the pygidial glands of the studied species was analysed for the first time. Morphological features of the pygidial glands were observed using bright-field microscopy and nonlinear microscopy and described in details.",
publisher = "Elsevier",
journal = "Zoology",
title = "Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae)",
volume = "142",
pages = "125772",
doi = "10.1016/j.zool.2020.125772"
}
Vranić, S., Ćurčić, S., Vesović, N., Mandić, B., Pantelić, D., Vasović, M., Lazović, V., Zhang, W.,& Vujisić, L. V.. (2020). Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae). in Zoology
Elsevier., 142, 125772.
https://doi.org/10.1016/j.zool.2020.125772
Vranić S, Ćurčić S, Vesović N, Mandić B, Pantelić D, Vasović M, Lazović V, Zhang W, Vujisić LV. Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae). in Zoology. 2020;142:125772.
doi:10.1016/j.zool.2020.125772 .
Vranić, Sofija, Ćurčić, Srećko, Vesović, Nikola, Mandić, Boris, Pantelić, Dejan, Vasović, Marija, Lazović, Vladimir, Zhang, Wang, Vujisić, Ljubodrag V., "Chemistry and morphology of the pygidial glands in four Pterostichini ground beetle taxa (Coleoptera: Carabidae: Pterostichinae)" in Zoology, 142 (2020):125772,
https://doi.org/10.1016/j.zool.2020.125772 . .
3
2
3

Population Diversity of n–Alkanes in the Needle Cuticular Wax of Relicts Pinus heldreichii and P. peuce from the Scardo-Pindic Mountains

Nikolić, Biljana M.; Đorđević, Iris; Todosijević, Marina; Mitić, Zorica S.; Bojović, Srdjan; Marin, Petar D.

(Macedonian Journal of Chemistry and Chemical Engineering, 2020)

TY  - JOUR
AU  - Nikolić, Biljana M.
AU  - Đorđević, Iris
AU  - Todosijević, Marina
AU  - Mitić, Zorica S.
AU  - Bojović, Srdjan
AU  - Marin, Petar D.
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4059
AB  - The variability of n-alkanes in the needle cuticular wax of Pinus heldreichii and P. peuce in two natural populations from the Scardo-Pindic mountains was investigated for the first time. Gas chromatography (GC) and gas chromatography/mass spectrometry (GC-MS) analyses of two-year-old needles were performed us-ing an Agilent 7890A GC equipped with an inert 5975C XL EI/CI mass spectrometer detector (MSD) and a flame ionization detector (FID) connected by a capillary flow technology 2-way splitter with make-up. An HP-5MS capillary column was used. n-Alkanes ranged from C19 to C33. In P. heldreichii the most abundant were C23, C25 and C27 (16.3, 15.6 and 12.8 % on average, respectively), while in P. peuce they were C29, C25, and C27 (16.5, 15.3 and 13.5 % on average, resp.). Mid-chain and long-chain n-alkanes prevailed in both species. Principle component analysis (PCA) and Cluster analyses of five and six n-alkanes, respectively, showed divergence of the Scardo-Pindic populations from the Dinaric ones.
PB  - Macedonian Journal of Chemistry and Chemical Engineering
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Population Diversity of n–Alkanes in the Needle Cuticular Wax of Relicts Pinus heldreichii and P. peuce from the Scardo-Pindic Mountains
VL  - 39
IS  - 1
SP  - 41
EP  - 48
DO  - 10.20450/mjcce.2020.1951
ER  - 
@article{
author = "Nikolić, Biljana M. and Đorđević, Iris and Todosijević, Marina and Mitić, Zorica S. and Bojović, Srdjan and Marin, Petar D.",
year = "2020",
abstract = "The variability of n-alkanes in the needle cuticular wax of Pinus heldreichii and P. peuce in two natural populations from the Scardo-Pindic mountains was investigated for the first time. Gas chromatography (GC) and gas chromatography/mass spectrometry (GC-MS) analyses of two-year-old needles were performed us-ing an Agilent 7890A GC equipped with an inert 5975C XL EI/CI mass spectrometer detector (MSD) and a flame ionization detector (FID) connected by a capillary flow technology 2-way splitter with make-up. An HP-5MS capillary column was used. n-Alkanes ranged from C19 to C33. In P. heldreichii the most abundant were C23, C25 and C27 (16.3, 15.6 and 12.8 % on average, respectively), while in P. peuce they were C29, C25, and C27 (16.5, 15.3 and 13.5 % on average, resp.). Mid-chain and long-chain n-alkanes prevailed in both species. Principle component analysis (PCA) and Cluster analyses of five and six n-alkanes, respectively, showed divergence of the Scardo-Pindic populations from the Dinaric ones.",
publisher = "Macedonian Journal of Chemistry and Chemical Engineering",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Population Diversity of n–Alkanes in the Needle Cuticular Wax of Relicts Pinus heldreichii and P. peuce from the Scardo-Pindic Mountains",
volume = "39",
number = "1",
pages = "41-48",
doi = "10.20450/mjcce.2020.1951"
}
Nikolić, B. M., Đorđević, I., Todosijević, M., Mitić, Z. S., Bojović, S.,& Marin, P. D.. (2020). Population Diversity of n–Alkanes in the Needle Cuticular Wax of Relicts Pinus heldreichii and P. peuce from the Scardo-Pindic Mountains. in Macedonian Journal of Chemistry and Chemical Engineering
Macedonian Journal of Chemistry and Chemical Engineering., 39(1), 41-48.
https://doi.org/10.20450/mjcce.2020.1951
Nikolić BM, Đorđević I, Todosijević M, Mitić ZS, Bojović S, Marin PD. Population Diversity of n–Alkanes in the Needle Cuticular Wax of Relicts Pinus heldreichii and P. peuce from the Scardo-Pindic Mountains. in Macedonian Journal of Chemistry and Chemical Engineering. 2020;39(1):41-48.
doi:10.20450/mjcce.2020.1951 .
Nikolić, Biljana M., Đorđević, Iris, Todosijević, Marina, Mitić, Zorica S., Bojović, Srdjan, Marin, Petar D., "Population Diversity of n–Alkanes in the Needle Cuticular Wax of Relicts Pinus heldreichii and P. peuce from the Scardo-Pindic Mountains" in Macedonian Journal of Chemistry and Chemical Engineering, 39, no. 1 (2020):41-48,
https://doi.org/10.20450/mjcce.2020.1951 . .

Ispitivanje hemijskog sastava sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia

Krstić, Gordana

(Универзитет у Београду, Хемијски факултет, 2019)

TY  - THES
AU  - Krstić, Gordana
PY  - 2019
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=7722
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:22941/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=23933961
UR  - https://nardus.mpn.gov.rs/handle/123456789/17673
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/4378
AB  - Predmet ove doktorske disertacije je proučavanje sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia koje nastanjuju naše prostore. Za ispitivanje su odabrane Euphorbia palustris L. (barska mlečika), Eupohorbia lucida Waldst. & Kit. (visoka mlečika) i Euphorbia nicaeensis All (uskolisna mlečika). Biljne vrste roda Euphorbia poznate su od davnina i našle su svoju praktičnu primenu u tradicionalnoj i savremenoj medicini. Za sve predstavnike ovog roda karakteristično je postojanje biljnog soka (lateks) koji se skadišti u posebnim ćelijama koje se nalaze u stablu i listovima biljaka. Lateks predstavlja vodenu emulziju smeše terpena, fenolnih jedinjenja, cerebrozida, glicerola i drugih jedinjenja koja ima zaštitno dejstvo za biljku. Najzastupljenija jedinjenja u lateksu pripadaju klasi terpena i to diterpenima i triterpenima...
AB  - The subject of this doctoral dissertation is the study of secondary metabolites of selected plant species of the genus Euphorbia that grow in our region. Euphorbia palustris L. (swamp spurge), Euphorbia lucida Waldst. & Kit. (shining spurge) and Euphorbia nicaeensis All. (narrow-leaved spurge) were selected for the research. Plant species of the genus Euphorbia have been known since ancient times and have found practical applications in traditional and modern medicine. All the plants of this genus are characterized by the existence of a milky sap (latex) which is stored in specialized cells found in the stem and leaves of the plants. Latex is an aqueous emulsion of a mixture of terpenes, phenolic compounds, cerebrosides, glycerols and other compounds that has a protective effect on the plant. Terpenes are the major components of the latex, namely diterpenes and triterpenes...
PB  - Универзитет у Београду, Хемијски факултет
T2  - Универзитет у Београду
T1  - Ispitivanje hemijskog sastava sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia
ER  - 
@phdthesis{
author = "Krstić, Gordana",
year = "2019",
abstract = "Predmet ove doktorske disertacije je proučavanje sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia koje nastanjuju naše prostore. Za ispitivanje su odabrane Euphorbia palustris L. (barska mlečika), Eupohorbia lucida Waldst. & Kit. (visoka mlečika) i Euphorbia nicaeensis All (uskolisna mlečika). Biljne vrste roda Euphorbia poznate su od davnina i našle su svoju praktičnu primenu u tradicionalnoj i savremenoj medicini. Za sve predstavnike ovog roda karakteristično je postojanje biljnog soka (lateks) koji se skadišti u posebnim ćelijama koje se nalaze u stablu i listovima biljaka. Lateks predstavlja vodenu emulziju smeše terpena, fenolnih jedinjenja, cerebrozida, glicerola i drugih jedinjenja koja ima zaštitno dejstvo za biljku. Najzastupljenija jedinjenja u lateksu pripadaju klasi terpena i to diterpenima i triterpenima..., The subject of this doctoral dissertation is the study of secondary metabolites of selected plant species of the genus Euphorbia that grow in our region. Euphorbia palustris L. (swamp spurge), Euphorbia lucida Waldst. & Kit. (shining spurge) and Euphorbia nicaeensis All. (narrow-leaved spurge) were selected for the research. Plant species of the genus Euphorbia have been known since ancient times and have found practical applications in traditional and modern medicine. All the plants of this genus are characterized by the existence of a milky sap (latex) which is stored in specialized cells found in the stem and leaves of the plants. Latex is an aqueous emulsion of a mixture of terpenes, phenolic compounds, cerebrosides, glycerols and other compounds that has a protective effect on the plant. Terpenes are the major components of the latex, namely diterpenes and triterpenes...",
publisher = "Универзитет у Београду, Хемијски факултет",
journal = "Универзитет у Београду",
title = "Ispitivanje hemijskog sastava sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia"
}
Krstić, G.. (2019). Ispitivanje hemijskog sastava sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia. in Универзитет у Београду
Универзитет у Београду, Хемијски факултет..
Krstić G. Ispitivanje hemijskog sastava sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia. in Универзитет у Београду. 2019;..
Krstić, Gordana, "Ispitivanje hemijskog sastava sekundarnih metabolita odabranih biljnih vrsta roda Euphorbia" in Универзитет у Београду (2019).

Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium

Gojgić-Cvijović, Gordana D.; Jakovljević, Dragica M.; Lončarević, Branka D.; Todorović, Nevena M.; Pergal, Marija V.; Ćirić, J.; Loos, K.; Beškoski, Vladimir; Vrvić, Miroslav M.

(2019)

TY  - JOUR
AU  - Gojgić-Cvijović, Gordana D.
AU  - Jakovljević, Dragica M.
AU  - Lončarević, Branka D.
AU  - Todorović, Nevena M.
AU  - Pergal, Marija V.
AU  - Ćirić, J.
AU  - Loos, K.
AU  - Beškoski, Vladimir
AU  - Vrvić, Miroslav M.
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2799
AB  - The production of levan by Bacillus licheniformis NS032 in a medium based on sugar beet molasses was studied. High polysaccharide yields were produced by using diluted molasses (100–140 g/L of total sugars) with the addition of commercial sucrose up to 200 g/L of total sugars, as well as K2HPO4. A levan yield of 53.2 g/L was obtained on a medium optimized by response surface methodology, containing 62.6% of sugar originating from molasses, and 4.66 g/L of phosphate, with initial pH value of 7.2. In comparison to the media with 200 and 400 g/L sucrose, in the molasses optimized medium, the observed bacterial growth was faster, while the maximum production of polysaccharide was achieved over a shorter time interval (48 h). The polysaccharide produced in molasses medium had a weight average molecular weight of 5.82 × 106 Da, degree of branching 12.68%, viscosity of 0.24 dL/g, and based on methylation analysis and NMR data, it did not significantly differ from levan obtained in the medium with 200 g/L sucrose. © 2018 Elsevier B.V.
T2  - International Journal of Biological Macromolecules
T1  - Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium
VL  - 121
SP  - 142
EP  - 151
DO  - 10.1016/j.ijbiomac.2018.10.019
ER  - 
@article{
author = "Gojgić-Cvijović, Gordana D. and Jakovljević, Dragica M. and Lončarević, Branka D. and Todorović, Nevena M. and Pergal, Marija V. and Ćirić, J. and Loos, K. and Beškoski, Vladimir and Vrvić, Miroslav M.",
year = "2019",
abstract = "The production of levan by Bacillus licheniformis NS032 in a medium based on sugar beet molasses was studied. High polysaccharide yields were produced by using diluted molasses (100–140 g/L of total sugars) with the addition of commercial sucrose up to 200 g/L of total sugars, as well as K2HPO4. A levan yield of 53.2 g/L was obtained on a medium optimized by response surface methodology, containing 62.6% of sugar originating from molasses, and 4.66 g/L of phosphate, with initial pH value of 7.2. In comparison to the media with 200 and 400 g/L sucrose, in the molasses optimized medium, the observed bacterial growth was faster, while the maximum production of polysaccharide was achieved over a shorter time interval (48 h). The polysaccharide produced in molasses medium had a weight average molecular weight of 5.82 × 106 Da, degree of branching 12.68%, viscosity of 0.24 dL/g, and based on methylation analysis and NMR data, it did not significantly differ from levan obtained in the medium with 200 g/L sucrose. © 2018 Elsevier B.V.",
journal = "International Journal of Biological Macromolecules",
title = "Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium",
volume = "121",
pages = "142-151",
doi = "10.1016/j.ijbiomac.2018.10.019"
}
Gojgić-Cvijović, G. D., Jakovljević, D. M., Lončarević, B. D., Todorović, N. M., Pergal, M. V., Ćirić, J., Loos, K., Beškoski, V.,& Vrvić, M. M.. (2019). Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium. in International Journal of Biological Macromolecules, 121, 142-151.
https://doi.org/10.1016/j.ijbiomac.2018.10.019
Gojgić-Cvijović GD, Jakovljević DM, Lončarević BD, Todorović NM, Pergal MV, Ćirić J, Loos K, Beškoski V, Vrvić MM. Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium. in International Journal of Biological Macromolecules. 2019;121:142-151.
doi:10.1016/j.ijbiomac.2018.10.019 .
Gojgić-Cvijović, Gordana D., Jakovljević, Dragica M., Lončarević, Branka D., Todorović, Nevena M., Pergal, Marija V., Ćirić, J., Loos, K., Beškoski, Vladimir, Vrvić, Miroslav M., "Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium" in International Journal of Biological Macromolecules, 121 (2019):142-151,
https://doi.org/10.1016/j.ijbiomac.2018.10.019 . .
26
21
25

Supplementary data for the article: Gojgic-Cvijovic, G. D.; Jakovljevic, D. M.; Loncarevic, B. D.; Todorovic, N. M.; Pergal, M. V.; Ciric, J.; Loos, K.; Beškoski, V.; Vrvić, M. M. Production of Levan by Bacillus Licheniformis NS032 in Sugar Beet Molasses-Based Medium. International Journal of Biological Macromolecules 2019, 121, 142–151. https://doi.org/10.1016/j.ijbiomac.2018.10.019

Gojgić-Cvijović, Gordana D.; Jakovljević, Dragica M.; Lončarević, Branka D.; Todorović, Nevena M.; Pergal, Marija V.; Ćirić, J.; Loos, K.; Beškoski, Vladimir; Vrvić, Miroslav M.

(2019)

TY  - DATA
AU  - Gojgić-Cvijović, Gordana D.
AU  - Jakovljević, Dragica M.
AU  - Lončarević, Branka D.
AU  - Todorović, Nevena M.
AU  - Pergal, Marija V.
AU  - Ćirić, J.
AU  - Loos, K.
AU  - Beškoski, Vladimir
AU  - Vrvić, Miroslav M.
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/2943
T2  - International Journal of Biological Macromolecules
T1  - Supplementary data for the article: Gojgic-Cvijovic, G. D.; Jakovljevic, D. M.; Loncarevic, B. D.; Todorovic, N. M.; Pergal, M. V.; Ciric, J.; Loos, K.; Beškoski, V.; Vrvić, M. M. Production of Levan by Bacillus Licheniformis NS032 in Sugar Beet Molasses-Based Medium. International Journal of Biological Macromolecules 2019, 121, 142–151. https://doi.org/10.1016/j.ijbiomac.2018.10.019
ER  - 
@misc{
author = "Gojgić-Cvijović, Gordana D. and Jakovljević, Dragica M. and Lončarević, Branka D. and Todorović, Nevena M. and Pergal, Marija V. and Ćirić, J. and Loos, K. and Beškoski, Vladimir and Vrvić, Miroslav M.",
year = "2019",
journal = "International Journal of Biological Macromolecules",
title = "Supplementary data for the article: Gojgic-Cvijovic, G. D.; Jakovljevic, D. M.; Loncarevic, B. D.; Todorovic, N. M.; Pergal, M. V.; Ciric, J.; Loos, K.; Beškoski, V.; Vrvić, M. M. Production of Levan by Bacillus Licheniformis NS032 in Sugar Beet Molasses-Based Medium. International Journal of Biological Macromolecules 2019, 121, 142–151. https://doi.org/10.1016/j.ijbiomac.2018.10.019"
}
Gojgić-Cvijović, G. D., Jakovljević, D. M., Lončarević, B. D., Todorović, N. M., Pergal, M. V., Ćirić, J., Loos, K., Beškoski, V.,& Vrvić, M. M.. (2019). Supplementary data for the article: Gojgic-Cvijovic, G. D.; Jakovljevic, D. M.; Loncarevic, B. D.; Todorovic, N. M.; Pergal, M. V.; Ciric, J.; Loos, K.; Beškoski, V.; Vrvić, M. M. Production of Levan by Bacillus Licheniformis NS032 in Sugar Beet Molasses-Based Medium. International Journal of Biological Macromolecules 2019, 121, 142–151. https://doi.org/10.1016/j.ijbiomac.2018.10.019. in International Journal of Biological Macromolecules.
Gojgić-Cvijović GD, Jakovljević DM, Lončarević BD, Todorović NM, Pergal MV, Ćirić J, Loos K, Beškoski V, Vrvić MM. Supplementary data for the article: Gojgic-Cvijovic, G. D.; Jakovljevic, D. M.; Loncarevic, B. D.; Todorovic, N. M.; Pergal, M. V.; Ciric, J.; Loos, K.; Beškoski, V.; Vrvić, M. M. Production of Levan by Bacillus Licheniformis NS032 in Sugar Beet Molasses-Based Medium. International Journal of Biological Macromolecules 2019, 121, 142–151. https://doi.org/10.1016/j.ijbiomac.2018.10.019. in International Journal of Biological Macromolecules. 2019;..
Gojgić-Cvijović, Gordana D., Jakovljević, Dragica M., Lončarević, Branka D., Todorović, Nevena M., Pergal, Marija V., Ćirić, J., Loos, K., Beškoski, Vladimir, Vrvić, Miroslav M., "Supplementary data for the article: Gojgic-Cvijovic, G. D.; Jakovljevic, D. M.; Loncarevic, B. D.; Todorovic, N. M.; Pergal, M. V.; Ciric, J.; Loos, K.; Beškoski, V.; Vrvić, M. M. Production of Levan by Bacillus Licheniformis NS032 in Sugar Beet Molasses-Based Medium. International Journal of Biological Macromolecules 2019, 121, 142–151. https://doi.org/10.1016/j.ijbiomac.2018.10.019" in International Journal of Biological Macromolecules (2019).

Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa

Stanković, Jovana; Gođevac, Dejan; Tešević, Vele; Dajić-Stevanović, Zora; Ćirić, Ana D.; Soković, Marina; Novaković, Miroslav M.

(American Chemical Society, 2019)

TY  - JOUR
AU  - Stanković, Jovana
AU  - Gođevac, Dejan
AU  - Tešević, Vele
AU  - Dajić-Stevanović, Zora
AU  - Ćirić, Ana D.
AU  - Soković, Marina
AU  - Novaković, Miroslav M.
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3725
AB  - A new flavonoid glucoside derivative, patuletin 3-O-(2-O-feruloyl)-β-d-glucuronopyranosyl-(1→2)-β-d-glucopyranoside, named atriplexin IV (1), and three new triterpenoid saponin derivatives, two sulfonylated, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside-30-alolean-12-en-28-oate (2), named atriplexogenin I, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside)-30-hydroxyolean-12-en-28-oate (3), named atriplexogenin II, and β-d-glucopyranosyl-3-O-(β-d-glucopyranosyl-(1→2)-β-d-galactopyranosyl-(1→2)-α-l-arabinopyranoside)-30-alolean-12-en-28-oate (4), named atriplexogenin III, were isolated by silica gel column and semipreparative HPLC chromatography from the n-butanol extract of the salt marsh plant Atriplex tatarica. In addition, two known secondary metabolites, patuletin3-O-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (5) and patuletin 3-O-5'-O-feruloyl-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (6), were isolated for the first time from A. tatarica. The structures of the isolated compounds were elucidated by 1D and 2D NMR, HRESIMS, IR, and UV data. Antibacterial activity by the microdilution method and antibiofilm activity against P. aeruginosa were assessed. Compound 5 possesses significant antibacterial activity, while the most potent antibiofilm agent is compound 2.
PB  - American Chemical Society
T2  - Journal of Natural Products
T1  - Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa
VL  - 82
IS  - 6
SP  - 1487
EP  - 1495
DO  - 10.1021/acs.jnatprod.8b00970
ER  - 
@article{
author = "Stanković, Jovana and Gođevac, Dejan and Tešević, Vele and Dajić-Stevanović, Zora and Ćirić, Ana D. and Soković, Marina and Novaković, Miroslav M.",
year = "2019",
abstract = "A new flavonoid glucoside derivative, patuletin 3-O-(2-O-feruloyl)-β-d-glucuronopyranosyl-(1→2)-β-d-glucopyranoside, named atriplexin IV (1), and three new triterpenoid saponin derivatives, two sulfonylated, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside-30-alolean-12-en-28-oate (2), named atriplexogenin I, β-d-glucopyranosyl-3-O-(2-O-sulfo-β-d-galactopyranosyl)-(1→2)-α-l-arabinopyranoside)-30-hydroxyolean-12-en-28-oate (3), named atriplexogenin II, and β-d-glucopyranosyl-3-O-(β-d-glucopyranosyl-(1→2)-β-d-galactopyranosyl-(1→2)-α-l-arabinopyranoside)-30-alolean-12-en-28-oate (4), named atriplexogenin III, were isolated by silica gel column and semipreparative HPLC chromatography from the n-butanol extract of the salt marsh plant Atriplex tatarica. In addition, two known secondary metabolites, patuletin3-O-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (5) and patuletin 3-O-5'-O-feruloyl-β-d-apiofuranosyl-(1'→2″)-β-d-glucopyranoside (6), were isolated for the first time from A. tatarica. The structures of the isolated compounds were elucidated by 1D and 2D NMR, HRESIMS, IR, and UV data. Antibacterial activity by the microdilution method and antibiofilm activity against P. aeruginosa were assessed. Compound 5 possesses significant antibacterial activity, while the most potent antibiofilm agent is compound 2.",
publisher = "American Chemical Society",
journal = "Journal of Natural Products",
title = "Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa",
volume = "82",
number = "6",
pages = "1487-1495",
doi = "10.1021/acs.jnatprod.8b00970"
}
Stanković, J., Gođevac, D., Tešević, V., Dajić-Stevanović, Z., Ćirić, A. D., Soković, M.,& Novaković, M. M.. (2019). Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. in Journal of Natural Products
American Chemical Society., 82(6), 1487-1495.
https://doi.org/10.1021/acs.jnatprod.8b00970
Stanković J, Gođevac D, Tešević V, Dajić-Stevanović Z, Ćirić AD, Soković M, Novaković MM. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. in Journal of Natural Products. 2019;82(6):1487-1495.
doi:10.1021/acs.jnatprod.8b00970 .
Stanković, Jovana, Gođevac, Dejan, Tešević, Vele, Dajić-Stevanović, Zora, Ćirić, Ana D., Soković, Marina, Novaković, Miroslav M., "Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa" in Journal of Natural Products, 82, no. 6 (2019):1487-1495,
https://doi.org/10.1021/acs.jnatprod.8b00970 . .
4
5
5
4

Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970

Stanković, Jovana; Gođevac, Dejan; Tešević, Vele; Dajić-Stevanović, Zora; Ćirić, Ana D.; Soković, Marina; Novaković, Miroslav M.

(American Chemical Society, 2019)

TY  - DATA
AU  - Stanković, Jovana
AU  - Gođevac, Dejan
AU  - Tešević, Vele
AU  - Dajić-Stevanović, Zora
AU  - Ćirić, Ana D.
AU  - Soković, Marina
AU  - Novaković, Miroslav M.
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3726
PB  - American Chemical Society
T2  - Journal of Natural Products
T1  - Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970
ER  - 
@misc{
author = "Stanković, Jovana and Gođevac, Dejan and Tešević, Vele and Dajić-Stevanović, Zora and Ćirić, Ana D. and Soković, Marina and Novaković, Miroslav M.",
year = "2019",
publisher = "American Chemical Society",
journal = "Journal of Natural Products",
title = "Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970"
}
Stanković, J., Gođevac, D., Tešević, V., Dajić-Stevanović, Z., Ćirić, A. D., Soković, M.,& Novaković, M. M.. (2019). Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970. in Journal of Natural Products
American Chemical Society..
Stanković J, Gođevac D, Tešević V, Dajić-Stevanović Z, Ćirić AD, Soković M, Novaković MM. Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970. in Journal of Natural Products. 2019;..
Stanković, Jovana, Gođevac, Dejan, Tešević, Vele, Dajić-Stevanović, Zora, Ćirić, Ana D., Soković, Marina, Novaković, Miroslav M., "Supplementary data for the article: Stanković, J.; Godevac, D.; Tešević, V.; Dajić-Stevanović, Z.; Ćirić, A.; Soković, M.; Novaković, M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex Tatarica against Pseudomonas Aeruginosa. Journal of Natural Products 2019, 82 (6), 1487–1495. https://doi.org/10.1021/acs.jnatprod.8b00970" in Journal of Natural Products (2019).

Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.)

Kokalj, Doris; Gođevac, Dejan; Anđelković, Boban D.; Cigić, Blaž; Zlatić, Emil; Hribar, Janez; Vidrih, Rajko

(International Society for Horticultural Science, 2019)

TY  - CONF
AU  - Kokalj, Doris
AU  - Gođevac, Dejan
AU  - Anđelković, Boban D.
AU  - Cigić, Blaž
AU  - Zlatić, Emil
AU  - Hribar, Janez
AU  - Vidrih, Rajko
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3736
AB  - A metabolomics approach based on nuclear magnetic resonance (NMR) spectroscopy, a rapid and simple technique, was used for the assessment of chemical changes of 'Van' sweet cherries during their storage. This approach affords a holistic analysis since NMR spectroscopy allows the simultaneous detection of diverse groups of secondary and primary metabolites, and reflects the real molar levels of the metabolites. Additionally, color parameters L∗, a∗ and b∗, total phenolic content (TPC), total flavonoid content (TFC), anthocyanidins and total antioxidant potential (AOP) were measured. After harvest, cherries were stored at 1°C and sampling was done after 0, 2, 4, 7 and 10 days. Cherry skin was removed, freeze dried and stored at -80°C till analyses. For NMR analyses, freeze dried cherry skins have been extracted with methanol-d4/trifluoroacetic acid-d solvent mixture. For other analyses, samples were extracted in 70% ethanol with 1% of formic acid. The 1D and 2D NMR spectral analysis confirmed that sugars (glucose, fructose, sucrose), organic acids (malic and citric acid), and phenolic compounds (neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside) are the main compounds in the cherry skin extracts. The 1H NMR spectral data have been subjected to multivariate analysis. Orthogonal projections to latent structures (OPLS) were applied to correlate the NMR data with the storage time. The changes in chemical composition among the samples with different storage time were clearly visible on the score plot. According to the goodness of fit of the model (R 2 =0.954), and its predictive ability (Q 2 =0.634), cherry skin extracts were well-correlated with the storage time. A positive correlation of the signals corresponding to glucose, neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside with the storage time of cherries has been observed on the loading plot. According to the loading plot, the increase in the content of glucose, neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside has been correlated with the storage time of cherries. Since polyphenolic compounds were found to correlate well with the storage time, the content of redox active compounds was further assessed with AOP, TPC and TFC. All these parameters were increasing for 7 days after harvest then started to decline slightly. The content of all three anthocyanidins increased 2 days after harvest then remained stable till the end of sampling period.
PB  - International Society for Horticultural Science
C3  - Acta Horticulturae
T1  - Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.)
VL  - 1235
SP  - 483
EP  - 488
DO  - 10.17660/ActaHortic.2019.1235.67
ER  - 
@conference{
author = "Kokalj, Doris and Gođevac, Dejan and Anđelković, Boban D. and Cigić, Blaž and Zlatić, Emil and Hribar, Janez and Vidrih, Rajko",
year = "2019",
abstract = "A metabolomics approach based on nuclear magnetic resonance (NMR) spectroscopy, a rapid and simple technique, was used for the assessment of chemical changes of 'Van' sweet cherries during their storage. This approach affords a holistic analysis since NMR spectroscopy allows the simultaneous detection of diverse groups of secondary and primary metabolites, and reflects the real molar levels of the metabolites. Additionally, color parameters L∗, a∗ and b∗, total phenolic content (TPC), total flavonoid content (TFC), anthocyanidins and total antioxidant potential (AOP) were measured. After harvest, cherries were stored at 1°C and sampling was done after 0, 2, 4, 7 and 10 days. Cherry skin was removed, freeze dried and stored at -80°C till analyses. For NMR analyses, freeze dried cherry skins have been extracted with methanol-d4/trifluoroacetic acid-d solvent mixture. For other analyses, samples were extracted in 70% ethanol with 1% of formic acid. The 1D and 2D NMR spectral analysis confirmed that sugars (glucose, fructose, sucrose), organic acids (malic and citric acid), and phenolic compounds (neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside) are the main compounds in the cherry skin extracts. The 1H NMR spectral data have been subjected to multivariate analysis. Orthogonal projections to latent structures (OPLS) were applied to correlate the NMR data with the storage time. The changes in chemical composition among the samples with different storage time were clearly visible on the score plot. According to the goodness of fit of the model (R 2 =0.954), and its predictive ability (Q 2 =0.634), cherry skin extracts were well-correlated with the storage time. A positive correlation of the signals corresponding to glucose, neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside with the storage time of cherries has been observed on the loading plot. According to the loading plot, the increase in the content of glucose, neochlorogenic acid, cyanidin 3-O-rutinoside, and cyanidin 3-O-glucoside has been correlated with the storage time of cherries. Since polyphenolic compounds were found to correlate well with the storage time, the content of redox active compounds was further assessed with AOP, TPC and TFC. All these parameters were increasing for 7 days after harvest then started to decline slightly. The content of all three anthocyanidins increased 2 days after harvest then remained stable till the end of sampling period.",
publisher = "International Society for Horticultural Science",
journal = "Acta Horticulturae",
title = "Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.)",
volume = "1235",
pages = "483-488",
doi = "10.17660/ActaHortic.2019.1235.67"
}
Kokalj, D., Gođevac, D., Anđelković, B. D., Cigić, B., Zlatić, E., Hribar, J.,& Vidrih, R.. (2019). Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.). in Acta Horticulturae
International Society for Horticultural Science., 1235, 483-488.
https://doi.org/10.17660/ActaHortic.2019.1235.67
Kokalj D, Gođevac D, Anđelković BD, Cigić B, Zlatić E, Hribar J, Vidrih R. Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.). in Acta Horticulturae. 2019;1235:483-488.
doi:10.17660/ActaHortic.2019.1235.67 .
Kokalj, Doris, Gođevac, Dejan, Anđelković, Boban D., Cigić, Blaž, Zlatić, Emil, Hribar, Janez, Vidrih, Rajko, "Nuclear magnetic resonance as a tool for the assessment of postharvest changes in the metabolome of the skin of sweet cherry (Prunus avium L.)" in Acta Horticulturae, 1235 (2019):483-488,
https://doi.org/10.17660/ActaHortic.2019.1235.67 . .

Metabolomička studija balkanskih vrsta roda Amphoricarpos Vis. (Asteraceae)

Cvetković, Mirjana

(Универзитет у Београду, Хемијски факултет, 2019)

TY  - THES
AU  - Cvetković, Mirjana
PY  - 2019
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=7045
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:20666/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=51737615
UR  - http://nardus.mpn.gov.rs/123456789/11706
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3908
AB  - Metabolomika je nova naučna multidisciplinarna oblast koja obuhvata različiteaspekte biologije, hemije i matematike. Koristi moderne spektroskopske ihromatografske tehnike (NMR, IC, UV, MS, GC, LC) i multivarijantnu statističkuanalizu podataka sa ciljem da se izmere kvantitativno i kvalitativno svi metaboliti uispitivanom organizmu i na taj način dobije jasna metabolomička slika pod ispitivanimuslovima. Primena metabolomike nije ograničena samo na biljni svet, već se možeprimeniti na sve žive organizme, pa tako i na ljude. Posebno je značajna mogućnostprimene u medicini kao dijagnostičke metode ili u farmakognoziji za otkrivanje novihlekovitih sirovina. U ovoj disertaciji primena metabolomike na endemski biljni rodAmphoricarpos Vis. imala je dva cilja: (a) sticanje novih saznanja o mogućnostiprimene dobijenih rezultata u diferencijaciji balkanskih vrsta ovog roda i (b) razvojmetode za brzo otkrivanje novih farmakološki aktivnih sastojaka u biljnom materijalu.Vrste roda Amphoricarpos Vis. rasprostranjene su na Balkanskom poluostrvu.Anatoliji i Kavkazu. Da bi se dobilo više uvida u taksonomski status balkanskih taksonaovog roda, koji nije do kraja raščišćen, primenjena je metabolomička studija. Po Blečićui Mayeru1 postoje tri taksona: dve vrste A. neumayeri Vis. i A. autariatus Blečić etMayer, koja se deli na dve podvrste - ssp. autariatus i ssp. bertisceus Blečić et Mayer. Sdruge strane, Webb2 priznaje samo jednu vrstu - A. neumayeri Vis., koja sadrži dvepodvrste - ssp. neumayeri i ssp. murbeckii Bošnjak. U novije vreme, na osnovuispitivanja genoma vrsta ovog roda predložena je samo jedna vrsta, А. neumayerianus(Vis.) Greuter.3 U ovom radu analizirana su sva tri taksona (prema Blečiću i Mayeru), auzorci su sakupljeni na različitim lokalitetima u Crnoj Gori u fazi cvetanja. Primenjenaje 1H NMR spektroskopija kombinovana sa multivarijantnom analizom podataka.Pokazano je da je OPLS-DA (engl. Orthogonal Partial Least Squares-DiscriminantAnalysis) najefikasniji metod za diskriminaciju ispitivanih uzoraka na osnovumetabolita prisutnih u ekstraktima. Utvrđeno je da je glavna razlika između A.autariatus i A. neumayeri prisustvo karakterističnih seskviterpenskih laktonagvajanolidnog tipa (amforikarpolida). Glavni seskviterpenski lakton vrste A. neumayerije oksidovan u položaju 2, dok laktoni prisutni u obe podvrste A. autariatus suoksidovani u poziciji 9, što potvrđuje da seskviterpenski laktoni mogu bitihemotaksonomski markeri u porodici Asteraceae...
AB  - Metabolomics is a new scientific multidisciplinary field that includes variousaspects of biology, chemistry and mathematics. It uses modern spectroscopic andchromatographic techniques (NMR, IC, UV, MS, GC, LC) and multivariate statisticaldata analysis to measure quantitatively and qualitatively all of the metabolites in the testorganism and thereby obtain a clear metabolic profile under test conditions. The use ofmetabolomics is not limited to the plant world, but can be applied to all livingorganisms as well as humans. A particularly important possibility is the application inmedicine as a diagnostic method or in pharmacognosy for the discovery of new naturalsources of drugs. In this thesis, the application of metabolomics to the endemic plantgenus Amphoricarpos Vis. was applied with two objectives: (a) acquiring newknowledge of the systematization of the genus, and (b) developing a method for rapiddetection of new pharmacologically active ingredients in plant material.Genus Amphoricarpos Vis. is an endemic of the western part of the BalkanPeninsula. In order to gain more insight into the taxonomic status of the genus that isstill ambiguous, a metabolomic study was applied. Blečić and Mayer1 proposed threetaxa: two species A. neumayeri Vis. and A. autariatus Blečić et Mayer, the latter dividedinto two subspecies, ssp. autariatus i ssp. bertisceus Blečič et Mayer. On the other hand,Webb2 recognizeed only one species, A. neumayeri Vis. divided into two subspecies,ssp. neumayeri i ssp. murbeckii Bošnjak. Recently, on the basis of a genomeexamination of the taxa from the West Balkans, only one species was proposed, A.neumayerianus (Vis.) Greuter.3In this dissertation all three taxa (according to Blečić and Mayer)1 were analysed. Thesamples were collected at different locations in Montenegro at the stage of flowering.1H NMR spectroscopy combined with multivariate data analysis was applied.Orthogonal Partial Least Squares-Discriminant Analysis (OPLS-DA) has been shown tobe the most effective method for discrimination of the tested samples, based on themetabolites present in the extracts. It was found that the main difference between A.autariatus and A. neumayeri was the presence of characteristic guaianolidesesquiterpene lactones (amforicarpolides). The major sesquiterpene lactones in theextract of A. neumayeri were oxidized in position 2, while the lactones present in bothsubspecies of A. autariatus were oxidized at position 9, which confirms thatsesquiterpene lactones may be chemotaxonomic markers in the Asteraceae family...
PB  - Универзитет у Београду, Хемијски факултет
T2  - Универзитет у Београду
T1  - Metabolomička studija balkanskih vrsta roda Amphoricarpos Vis. (Asteraceae)
ER  - 
@phdthesis{
author = "Cvetković, Mirjana",
year = "2019",
abstract = "Metabolomika je nova naučna multidisciplinarna oblast koja obuhvata različiteaspekte biologije, hemije i matematike. Koristi moderne spektroskopske ihromatografske tehnike (NMR, IC, UV, MS, GC, LC) i multivarijantnu statističkuanalizu podataka sa ciljem da se izmere kvantitativno i kvalitativno svi metaboliti uispitivanom organizmu i na taj način dobije jasna metabolomička slika pod ispitivanimuslovima. Primena metabolomike nije ograničena samo na biljni svet, već se možeprimeniti na sve žive organizme, pa tako i na ljude. Posebno je značajna mogućnostprimene u medicini kao dijagnostičke metode ili u farmakognoziji za otkrivanje novihlekovitih sirovina. U ovoj disertaciji primena metabolomike na endemski biljni rodAmphoricarpos Vis. imala je dva cilja: (a) sticanje novih saznanja o mogućnostiprimene dobijenih rezultata u diferencijaciji balkanskih vrsta ovog roda i (b) razvojmetode za brzo otkrivanje novih farmakološki aktivnih sastojaka u biljnom materijalu.Vrste roda Amphoricarpos Vis. rasprostranjene su na Balkanskom poluostrvu.Anatoliji i Kavkazu. Da bi se dobilo više uvida u taksonomski status balkanskih taksonaovog roda, koji nije do kraja raščišćen, primenjena je metabolomička studija. Po Blečićui Mayeru1 postoje tri taksona: dve vrste A. neumayeri Vis. i A. autariatus Blečić etMayer, koja se deli na dve podvrste - ssp. autariatus i ssp. bertisceus Blečić et Mayer. Sdruge strane, Webb2 priznaje samo jednu vrstu - A. neumayeri Vis., koja sadrži dvepodvrste - ssp. neumayeri i ssp. murbeckii Bošnjak. U novije vreme, na osnovuispitivanja genoma vrsta ovog roda predložena je samo jedna vrsta, А. neumayerianus(Vis.) Greuter.3 U ovom radu analizirana su sva tri taksona (prema Blečiću i Mayeru), auzorci su sakupljeni na različitim lokalitetima u Crnoj Gori u fazi cvetanja. Primenjenaje 1H NMR spektroskopija kombinovana sa multivarijantnom analizom podataka.Pokazano je da je OPLS-DA (engl. Orthogonal Partial Least Squares-DiscriminantAnalysis) najefikasniji metod za diskriminaciju ispitivanih uzoraka na osnovumetabolita prisutnih u ekstraktima. Utvrđeno je da je glavna razlika između A.autariatus i A. neumayeri prisustvo karakterističnih seskviterpenskih laktonagvajanolidnog tipa (amforikarpolida). Glavni seskviterpenski lakton vrste A. neumayerije oksidovan u položaju 2, dok laktoni prisutni u obe podvrste A. autariatus suoksidovani u poziciji 9, što potvrđuje da seskviterpenski laktoni mogu bitihemotaksonomski markeri u porodici Asteraceae..., Metabolomics is a new scientific multidisciplinary field that includes variousaspects of biology, chemistry and mathematics. It uses modern spectroscopic andchromatographic techniques (NMR, IC, UV, MS, GC, LC) and multivariate statisticaldata analysis to measure quantitatively and qualitatively all of the metabolites in the testorganism and thereby obtain a clear metabolic profile under test conditions. The use ofmetabolomics is not limited to the plant world, but can be applied to all livingorganisms as well as humans. A particularly important possibility is the application inmedicine as a diagnostic method or in pharmacognosy for the discovery of new naturalsources of drugs. In this thesis, the application of metabolomics to the endemic plantgenus Amphoricarpos Vis. was applied with two objectives: (a) acquiring newknowledge of the systematization of the genus, and (b) developing a method for rapiddetection of new pharmacologically active ingredients in plant material.Genus Amphoricarpos Vis. is an endemic of the western part of the BalkanPeninsula. In order to gain more insight into the taxonomic status of the genus that isstill ambiguous, a metabolomic study was applied. Blečić and Mayer1 proposed threetaxa: two species A. neumayeri Vis. and A. autariatus Blečić et Mayer, the latter dividedinto two subspecies, ssp. autariatus i ssp. bertisceus Blečič et Mayer. On the other hand,Webb2 recognizeed only one species, A. neumayeri Vis. divided into two subspecies,ssp. neumayeri i ssp. murbeckii Bošnjak. Recently, on the basis of a genomeexamination of the taxa from the West Balkans, only one species was proposed, A.neumayerianus (Vis.) Greuter.3In this dissertation all three taxa (according to Blečić and Mayer)1 were analysed. Thesamples were collected at different locations in Montenegro at the stage of flowering.1H NMR spectroscopy combined with multivariate data analysis was applied.Orthogonal Partial Least Squares-Discriminant Analysis (OPLS-DA) has been shown tobe the most effective method for discrimination of the tested samples, based on themetabolites present in the extracts. It was found that the main difference between A.autariatus and A. neumayeri was the presence of characteristic guaianolidesesquiterpene lactones (amforicarpolides). The major sesquiterpene lactones in theextract of A. neumayeri were oxidized in position 2, while the lactones present in bothsubspecies of A. autariatus were oxidized at position 9, which confirms thatsesquiterpene lactones may be chemotaxonomic markers in the Asteraceae family...",
publisher = "Универзитет у Београду, Хемијски факултет",
journal = "Универзитет у Београду",
title = "Metabolomička studija balkanskih vrsta roda Amphoricarpos Vis. (Asteraceae)"
}
Cvetković, M.. (2019). Metabolomička studija balkanskih vrsta roda Amphoricarpos Vis. (Asteraceae). in Универзитет у Београду
Универзитет у Београду, Хемијски факултет..
Cvetković M. Metabolomička studija balkanskih vrsta roda Amphoricarpos Vis. (Asteraceae). in Универзитет у Београду. 2019;..
Cvetković, Mirjana, "Metabolomička studija balkanskih vrsta roda Amphoricarpos Vis. (Asteraceae)" in Универзитет у Београду (2019).

Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita

Stanković, Jovana

(Универзитет у Београду, Хемијски факултет, 2019)

TY  - THES
AU  - Stanković, Jovana
PY  - 2019
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=7015
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:20623/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=51738383
UR  - http://nardus.mpn.gov.rs/123456789/11672
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3909
AB  - Predmet proučavanja ove doktorske disertacije su sekundarni metaboliti halofita(biljaka koje naseljavaju staništa sa visokim sadržajem soli). U Srbiji se zaslanjenastaništa uglavnom javljaju na teritoriji Vojvodine. U ovom radu izolovani su i hemijskiokarakterisani flavonoidni glikozidi i saponini iz halofitnih vrsta roda Atriplex (A.littoralis, A. tatarica i A. prostrata) i određena je njihova različita biološka aktivnost.Pored biljaka iz roda Atriplex ispitivana je halofitna biljna vrsta Artemisia santonicum izkoje je izolovano etarsko ulje, određen hemijski sastav i ispitana biološka aktivnost.Halofitne biljne vrste se u tradicionalnoj medicini koriste u brojne svrhe kaoantiseptici, diuretici, antiparazitici, antipiretici, purgativi, laksativi, za lečenjedijabetesa, visokog krvnog pritiska, astme, gihta i reumatizma. Ekstrakti i jedinjenjaizolovana iz vrsta roda Atriplex pokazuju antioksidativnu, antimikrobnu, citotoksičnu,antiparazitsku, i insekticidnu aktivnost. Etarska ulja vrsta roda Artemisia su pokazalaantioksidativnu, antibakterijsku, antifungalnu, antiparazitsku, hepatoprotektivnu,neuroprotektivnu i antimalarijsku aktivnost.Vrste roda Atriplex su bogat izvor sekundarnih metabolita prvenstvenoflavonoida, saponina i alkaloida. U okviru ove disertacije izolovano je i okarakterisanoukupno 13 jedinjenja, od kojih je 7 novih prirodnih proizvoda (43-45, 51-54). Iz vrste A.littoralis izolovano je 6 jedinjenja, četiri flavonoidna glikozida (43-46) i dva fenolnajedinjenja (47, 48). Iz A. tatarica izolovano je 6 jedinjenja, tri flavonoidna glikozida(49-51) i tri triterpenska saponina oleanolnog tipa (52-54). Iz etarskog ulja Artemisiasantonicum izolovan je oksigenovani monoterpen (55)...
AB  - The subject of this doctoral dissertation are the secondary metabolites ofhalophytes (plants wild growing at saline habitats). In Serbia such habitats are mainlyfound in Vojvodina. Flavonoid glycosides and saponins from halophytic speciesAtriplex (A. littoralis, A. tatarica and A. prostrata) were isolated, chemicallycharacterized and their various biological activities were determined. In addition, ahalophyte species from the genus Artemisia (A. santonicum) was examined. Its essentialoil was isolated, the chemical composition determined and various biological activitiesof this were tested.Several halophytic plant species are used in many traditional formulations asantiseptics, diuretics, antiparasitics, antipyretics, purgatives, laxatives, for the treatmentof diabetes, high blood pressure, asthma, gout and rheumatism. Extracts and compoundsisolated from the genus Atriplex show antiparasitic, insecticidal, antimicrobial,cytotoxic and antioxidant activity. Essential oils of the genus Artemisia have shownantioxidant, antibacterial, antifungal, antiparasitic, hepatoprotective, neuroprotectiveand antimalarial activity.Atriplex species are a rich source of secondary metabolites, primarily flavonoids,saponins and alkaloids. In this study, a total of 13 compounds were isolated andcharacterized by means of spectroscopic techniques (1D and 2D NMR, IR and MS).Among them seven (43-45, 51-54) were the new compounds. At the same time, in theextract of A. littoralis, six compounds, four flavonoid glycosides (43-46) and twophenolic compounds (47, 48) were identified. From A. tatarica six compounds, threeflavonoid glycosides (49-51) and three triterpene saponins of an oleanane type (52-54)were isolated. An oxygenated monoterpene (55) was isolated from Artemisiasantonicum essential oil...
PB  - Универзитет у Београду, Хемијски факултет
T2  - Универзитет у Београду
T1  - Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita
ER  - 
@phdthesis{
author = "Stanković, Jovana",
year = "2019",
abstract = "Predmet proučavanja ove doktorske disertacije su sekundarni metaboliti halofita(biljaka koje naseljavaju staništa sa visokim sadržajem soli). U Srbiji se zaslanjenastaništa uglavnom javljaju na teritoriji Vojvodine. U ovom radu izolovani su i hemijskiokarakterisani flavonoidni glikozidi i saponini iz halofitnih vrsta roda Atriplex (A.littoralis, A. tatarica i A. prostrata) i određena je njihova različita biološka aktivnost.Pored biljaka iz roda Atriplex ispitivana je halofitna biljna vrsta Artemisia santonicum izkoje je izolovano etarsko ulje, određen hemijski sastav i ispitana biološka aktivnost.Halofitne biljne vrste se u tradicionalnoj medicini koriste u brojne svrhe kaoantiseptici, diuretici, antiparazitici, antipiretici, purgativi, laksativi, za lečenjedijabetesa, visokog krvnog pritiska, astme, gihta i reumatizma. Ekstrakti i jedinjenjaizolovana iz vrsta roda Atriplex pokazuju antioksidativnu, antimikrobnu, citotoksičnu,antiparazitsku, i insekticidnu aktivnost. Etarska ulja vrsta roda Artemisia su pokazalaantioksidativnu, antibakterijsku, antifungalnu, antiparazitsku, hepatoprotektivnu,neuroprotektivnu i antimalarijsku aktivnost.Vrste roda Atriplex su bogat izvor sekundarnih metabolita prvenstvenoflavonoida, saponina i alkaloida. U okviru ove disertacije izolovano je i okarakterisanoukupno 13 jedinjenja, od kojih je 7 novih prirodnih proizvoda (43-45, 51-54). Iz vrste A.littoralis izolovano je 6 jedinjenja, četiri flavonoidna glikozida (43-46) i dva fenolnajedinjenja (47, 48). Iz A. tatarica izolovano je 6 jedinjenja, tri flavonoidna glikozida(49-51) i tri triterpenska saponina oleanolnog tipa (52-54). Iz etarskog ulja Artemisiasantonicum izolovan je oksigenovani monoterpen (55)..., The subject of this doctoral dissertation are the secondary metabolites ofhalophytes (plants wild growing at saline habitats). In Serbia such habitats are mainlyfound in Vojvodina. Flavonoid glycosides and saponins from halophytic speciesAtriplex (A. littoralis, A. tatarica and A. prostrata) were isolated, chemicallycharacterized and their various biological activities were determined. In addition, ahalophyte species from the genus Artemisia (A. santonicum) was examined. Its essentialoil was isolated, the chemical composition determined and various biological activitiesof this were tested.Several halophytic plant species are used in many traditional formulations asantiseptics, diuretics, antiparasitics, antipyretics, purgatives, laxatives, for the treatmentof diabetes, high blood pressure, asthma, gout and rheumatism. Extracts and compoundsisolated from the genus Atriplex show antiparasitic, insecticidal, antimicrobial,cytotoxic and antioxidant activity. Essential oils of the genus Artemisia have shownantioxidant, antibacterial, antifungal, antiparasitic, hepatoprotective, neuroprotectiveand antimalarial activity.Atriplex species are a rich source of secondary metabolites, primarily flavonoids,saponins and alkaloids. In this study, a total of 13 compounds were isolated andcharacterized by means of spectroscopic techniques (1D and 2D NMR, IR and MS).Among them seven (43-45, 51-54) were the new compounds. At the same time, in theextract of A. littoralis, six compounds, four flavonoid glycosides (43-46) and twophenolic compounds (47, 48) were identified. From A. tatarica six compounds, threeflavonoid glycosides (49-51) and three triterpene saponins of an oleanane type (52-54)were isolated. An oxygenated monoterpene (55) was isolated from Artemisiasantonicum essential oil...",
publisher = "Универзитет у Београду, Хемијски факултет",
journal = "Универзитет у Београду",
title = "Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita"
}
Stanković, J.. (2019). Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita. in Универзитет у Београду
Универзитет у Београду, Хемијски факултет..
Stanković J. Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita. in Универзитет у Београду. 2019;..
Stanković, Jovana, "Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita" in Универзитет у Београду (2019).

Volatile composition, colour, and sensory quality of spirit-based beverages enriched with Medicinal Fungus Ganoderma lucidum and Herbal Extract

Veljović, Sonja P.; Tomić, Nikola S.; Belović, Miona M.; Nikićević, Ninoslav; Vukosavljević, Predrag V.; Nikšić, Miomir P.; Tešević, Vele

(University of Zagreb, 2019)

TY  - JOUR
AU  - Veljović, Sonja P.
AU  - Tomić, Nikola S.
AU  - Belović, Miona M.
AU  - Nikićević, Ninoslav
AU  - Vukosavljević, Predrag V.
AU  - Nikšić, Miomir P.
AU  - Tešević, Vele
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3681
AB  - The multicomponent mixtures consisting of herbs and fungi are commonly used for the production of alcoholic beverages with potential health-promoting effects in many Asian countries. The medicinal fungus Ganoderma lucidum is one of the most important fungi used for spirit production. Although this fungus affects the aromatic complexity of spirits, only a small number of studies have focused on investigating the influence of G. lucidum on the aromatic profile and colour of spirits. The aim of the research is to evaluate the influence of adding G. lucidum and herbal extract on final concentrations of volatile compounds and sensory quality of several distillates. In this study, distillates (grain, plum, grape and wine) were used to produce new spirit-based beverages with the fungus G. lucidum only, or with the fungus and herbal extract. Fifty-nine aroma compounds were identified by GC-MS. The aromatic profiles were strongly influenced by the primary aromas of the distillates, but the addition of G. lucidum and herbal extract enriched the volatile fraction of distillates with a range of ethyl esters, with a fruity and floral fragrance. Higher alcohols, 1-propanol, 2-isobutanol and isoamyl alcohol, were the most abundant volatile compounds in the analyzed distillates and spirits. The lightness of distillates was from 60.7 to 63.6, and with the addition of Ganoderma it significantly decreased to the range from 43.6 to 50.5. The addition of the fungus also increased the intensity of red and yellow colours. The Ganoderma spirits scored very highly in sensory evaluation (17.6-18.3), significantly better than the spirits without any additions (16.1-16.9).
PB  - University of Zagreb
T2  - Food Technology and Biotechnology
T1  - Volatile composition, colour, and sensory quality of spirit-based beverages enriched with Medicinal Fungus Ganoderma lucidum and Herbal Extract
VL  - 57
IS  - 3
SP  - 408
EP  - 417
DO  - 10.17113/ftb.57.03.19.6106
ER  - 
@article{
author = "Veljović, Sonja P. and Tomić, Nikola S. and Belović, Miona M. and Nikićević, Ninoslav and Vukosavljević, Predrag V. and Nikšić, Miomir P. and Tešević, Vele",
year = "2019",
abstract = "The multicomponent mixtures consisting of herbs and fungi are commonly used for the production of alcoholic beverages with potential health-promoting effects in many Asian countries. The medicinal fungus Ganoderma lucidum is one of the most important fungi used for spirit production. Although this fungus affects the aromatic complexity of spirits, only a small number of studies have focused on investigating the influence of G. lucidum on the aromatic profile and colour of spirits. The aim of the research is to evaluate the influence of adding G. lucidum and herbal extract on final concentrations of volatile compounds and sensory quality of several distillates. In this study, distillates (grain, plum, grape and wine) were used to produce new spirit-based beverages with the fungus G. lucidum only, or with the fungus and herbal extract. Fifty-nine aroma compounds were identified by GC-MS. The aromatic profiles were strongly influenced by the primary aromas of the distillates, but the addition of G. lucidum and herbal extract enriched the volatile fraction of distillates with a range of ethyl esters, with a fruity and floral fragrance. Higher alcohols, 1-propanol, 2-isobutanol and isoamyl alcohol, were the most abundant volatile compounds in the analyzed distillates and spirits. The lightness of distillates was from 60.7 to 63.6, and with the addition of Ganoderma it significantly decreased to the range from 43.6 to 50.5. The addition of the fungus also increased the intensity of red and yellow colours. The Ganoderma spirits scored very highly in sensory evaluation (17.6-18.3), significantly better than the spirits without any additions (16.1-16.9).",
publisher = "University of Zagreb",
journal = "Food Technology and Biotechnology",
title = "Volatile composition, colour, and sensory quality of spirit-based beverages enriched with Medicinal Fungus Ganoderma lucidum and Herbal Extract",
volume = "57",
number = "3",
pages = "408-417",
doi = "10.17113/ftb.57.03.19.6106"
}
Veljović, S. P., Tomić, N. S., Belović, M. M., Nikićević, N., Vukosavljević, P. V., Nikšić, M. P.,& Tešević, V.. (2019). Volatile composition, colour, and sensory quality of spirit-based beverages enriched with Medicinal Fungus Ganoderma lucidum and Herbal Extract. in Food Technology and Biotechnology
University of Zagreb., 57(3), 408-417.
https://doi.org/10.17113/ftb.57.03.19.6106
Veljović SP, Tomić NS, Belović MM, Nikićević N, Vukosavljević PV, Nikšić MP, Tešević V. Volatile composition, colour, and sensory quality of spirit-based beverages enriched with Medicinal Fungus Ganoderma lucidum and Herbal Extract. in Food Technology and Biotechnology. 2019;57(3):408-417.
doi:10.17113/ftb.57.03.19.6106 .
Veljović, Sonja P., Tomić, Nikola S., Belović, Miona M., Nikićević, Ninoslav, Vukosavljević, Predrag V., Nikšić, Miomir P., Tešević, Vele, "Volatile composition, colour, and sensory quality of spirit-based beverages enriched with Medicinal Fungus Ganoderma lucidum and Herbal Extract" in Food Technology and Biotechnology, 57, no. 3 (2019):408-417,
https://doi.org/10.17113/ftb.57.03.19.6106 . .
3
3
3

Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata

Novaković, Miroslav M.; Bukvicki, Danka; Anđelković, Boban D.; Ilić-Tomić, Tatjana; Veljić, Milan; Tešević, Vele; Asakawa, Yoshinori

(American Chemical Society and American Society of Pharmacognosy, 2019)

TY  - JOUR
AU  - Novaković, Miroslav M.
AU  - Bukvicki, Danka
AU  - Anđelković, Boban D.
AU  - Ilić-Tomić, Tatjana
AU  - Veljić, Milan
AU  - Tešević, Vele
AU  - Asakawa, Yoshinori
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3096
AB  - Seven new bisbibenzyls (1-7) were isolated from the methanol extract of the liverwort Lunularia cruciata along with one previously known bibenzyl and five known bisbibenzyls. The structures of compounds 1-7 were elucidated on the basis of the spectroscopic data. These newly isolated bisbibenzyls may be divided into two groups, the acyclic bisbibenzyls, perrottetins (1-3), and the cyclic analogues, riccardins (4-7). Besides standard perrottetin and riccardin structures (1 and 4, respectively), they contain phenanthrene (3 and 5), dihydrophenanthrene (2), and quinone moieties (6 and 7), rarely found in natural products. The new compounds 3 and 5, as well as the known riccardin G, exhibited cytotoxic activity against the A549 lung cancer cell line with IC 50 values of 5.0, 5.0, and 2.5 μM, respectively.
PB  - American Chemical Society and American Society of Pharmacognosy
T2  - Journal of Natural Products
T1  - Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata
VL  - 82
IS  - 4
SP  - 694
EP  - 701
DO  - 10.1021/acs.jnatprod.8b00390
ER  - 
@article{
author = "Novaković, Miroslav M. and Bukvicki, Danka and Anđelković, Boban D. and Ilić-Tomić, Tatjana and Veljić, Milan and Tešević, Vele and Asakawa, Yoshinori",
year = "2019",
abstract = "Seven new bisbibenzyls (1-7) were isolated from the methanol extract of the liverwort Lunularia cruciata along with one previously known bibenzyl and five known bisbibenzyls. The structures of compounds 1-7 were elucidated on the basis of the spectroscopic data. These newly isolated bisbibenzyls may be divided into two groups, the acyclic bisbibenzyls, perrottetins (1-3), and the cyclic analogues, riccardins (4-7). Besides standard perrottetin and riccardin structures (1 and 4, respectively), they contain phenanthrene (3 and 5), dihydrophenanthrene (2), and quinone moieties (6 and 7), rarely found in natural products. The new compounds 3 and 5, as well as the known riccardin G, exhibited cytotoxic activity against the A549 lung cancer cell line with IC 50 values of 5.0, 5.0, and 2.5 μM, respectively.",
publisher = "American Chemical Society and American Society of Pharmacognosy",
journal = "Journal of Natural Products",
title = "Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata",
volume = "82",
number = "4",
pages = "694-701",
doi = "10.1021/acs.jnatprod.8b00390"
}
Novaković, M. M., Bukvicki, D., Anđelković, B. D., Ilić-Tomić, T., Veljić, M., Tešević, V.,& Asakawa, Y.. (2019). Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata. in Journal of Natural Products
American Chemical Society and American Society of Pharmacognosy., 82(4), 694-701.
https://doi.org/10.1021/acs.jnatprod.8b00390
Novaković MM, Bukvicki D, Anđelković BD, Ilić-Tomić T, Veljić M, Tešević V, Asakawa Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata. in Journal of Natural Products. 2019;82(4):694-701.
doi:10.1021/acs.jnatprod.8b00390 .
Novaković, Miroslav M., Bukvicki, Danka, Anđelković, Boban D., Ilić-Tomić, Tatjana, Veljić, Milan, Tešević, Vele, Asakawa, Yoshinori, "Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia cruciata" in Journal of Natural Products, 82, no. 4 (2019):694-701,
https://doi.org/10.1021/acs.jnatprod.8b00390 . .
1
6
5
6

Supplementary data for article: Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390

Novaković, Miroslav M.; Bukvicki, Danka; Anđelković, Boban D.; Ilić-Tomić, Tatjana; Veljić, Milan; Tešević, Vele; Asakawa, Yoshinori

(American Chemical Society and American Society of Pharmacognosy, 2019)

TY  - DATA
AU  - Novaković, Miroslav M.
AU  - Bukvicki, Danka
AU  - Anđelković, Boban D.
AU  - Ilić-Tomić, Tatjana
AU  - Veljić, Milan
AU  - Tešević, Vele
AU  - Asakawa, Yoshinori
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3097
PB  - American Chemical Society and American Society of Pharmacognosy
T2  - Journal of Natural Products
T1  - Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390
ER  - 
@misc{
author = "Novaković, Miroslav M. and Bukvicki, Danka and Anđelković, Boban D. and Ilić-Tomić, Tatjana and Veljić, Milan and Tešević, Vele and Asakawa, Yoshinori",
year = "2019",
publisher = "American Chemical Society and American Society of Pharmacognosy",
journal = "Journal of Natural Products",
title = "Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390"
}
Novaković, M. M., Bukvicki, D., Anđelković, B. D., Ilić-Tomić, T., Veljić, M., Tešević, V.,& Asakawa, Y.. (2019). Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390. in Journal of Natural Products
American Chemical Society and American Society of Pharmacognosy..
Novaković MM, Bukvicki D, Anđelković BD, Ilić-Tomić T, Veljić M, Tešević V, Asakawa Y. Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390. in Journal of Natural Products. 2019;..
Novaković, Miroslav M., Bukvicki, Danka, Anđelković, Boban D., Ilić-Tomić, Tatjana, Veljić, Milan, Tešević, Vele, Asakawa, Yoshinori, "Supplementary data for article:   	Novakovic, M.; Bukvicki, D.; Andjelkovic, B.; Ilic-Tomic, T.; Veljic, M.; Tesevic, V.; Asakawa, Y. Cytotoxic Activity of Riccardin and Perrottetin Derivatives from the Liverwort Lunularia Cruciata. Journal of Natural Products 2019, 82 (4), 694–701. https://doi.org/10.1021/acs.jnatprod.8b00390" in Journal of Natural Products (2019).

Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium

Gojgić-Cvijović, Gordana D.; Jakovljević, Dragica M.; Lončarević, Branka D.; Todorović, Nevena M.; Pergal, Marija V.; Ćirić, J.; Loos, K.; Beškoski, Vladimir; Vrvić, Miroslav M.

(2019)

TY  - JOUR
AU  - Gojgić-Cvijović, Gordana D.
AU  - Jakovljević, Dragica M.
AU  - Lončarević, Branka D.
AU  - Todorović, Nevena M.
AU  - Pergal, Marija V.
AU  - Ćirić, J.
AU  - Loos, K.
AU  - Beškoski, Vladimir
AU  - Vrvić, Miroslav M.
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/350
AB  - The production of levan by Bacillus licheniformis NS032 in a medium based on sugar beet molasses was studied. High polysaccharide yields were produced by using diluted molasses (100–140 g/L of total sugars) with the addition of commercial sucrose up to 200 g/L of total sugars, as well as K2HPO4. A levan yield of 53.2 g/L was obtained on a medium optimized by response surface methodology, containing 62.6% of sugar originating from molasses, and 4.66 g/L of phosphate, with initial pH value of 7.2. In comparison to the media with 200 and 400 g/L sucrose, in the molasses optimized medium, the observed bacterial growth was faster, while the maximum production of polysaccharide was achieved over a shorter time interval (48 h). The polysaccharide produced in molasses medium had a weight average molecular weight of 5.82 × 106 Da, degree of branching 12.68%, viscosity of 0.24 dL/g, and based on methylation analysis and NMR data, it did not significantly differ from levan obtained in the medium with 200 g/L sucrose. © 2018 Elsevier B.V.
T2  - International Journal of Biological Macromolecules
T1  - Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium
VL  - 121
SP  - 142
EP  - 151
DO  - 10.1016/j.ijbiomac.2018.10.019
UR  - Kon_1321
ER  - 
@article{
author = "Gojgić-Cvijović, Gordana D. and Jakovljević, Dragica M. and Lončarević, Branka D. and Todorović, Nevena M. and Pergal, Marija V. and Ćirić, J. and Loos, K. and Beškoski, Vladimir and Vrvić, Miroslav M.",
year = "2019",
abstract = "The production of levan by Bacillus licheniformis NS032 in a medium based on sugar beet molasses was studied. High polysaccharide yields were produced by using diluted molasses (100–140 g/L of total sugars) with the addition of commercial sucrose up to 200 g/L of total sugars, as well as K2HPO4. A levan yield of 53.2 g/L was obtained on a medium optimized by response surface methodology, containing 62.6% of sugar originating from molasses, and 4.66 g/L of phosphate, with initial pH value of 7.2. In comparison to the media with 200 and 400 g/L sucrose, in the molasses optimized medium, the observed bacterial growth was faster, while the maximum production of polysaccharide was achieved over a shorter time interval (48 h). The polysaccharide produced in molasses medium had a weight average molecular weight of 5.82 × 106 Da, degree of branching 12.68%, viscosity of 0.24 dL/g, and based on methylation analysis and NMR data, it did not significantly differ from levan obtained in the medium with 200 g/L sucrose. © 2018 Elsevier B.V.",
journal = "International Journal of Biological Macromolecules",
title = "Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium",
volume = "121",
pages = "142-151",
doi = "10.1016/j.ijbiomac.2018.10.019",
url = "Kon_1321"
}
Gojgić-Cvijović, G. D., Jakovljević, D. M., Lončarević, B. D., Todorović, N. M., Pergal, M. V., Ćirić, J., Loos, K., Beškoski, V.,& Vrvić, M. M.. (2019). Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium. in International Journal of Biological Macromolecules, 121, 142-151.
https://doi.org/10.1016/j.ijbiomac.2018.10.019
Kon_1321
Gojgić-Cvijović GD, Jakovljević DM, Lončarević BD, Todorović NM, Pergal MV, Ćirić J, Loos K, Beškoski V, Vrvić MM. Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium. in International Journal of Biological Macromolecules. 2019;121:142-151.
doi:10.1016/j.ijbiomac.2018.10.019
Kon_1321 .
Gojgić-Cvijović, Gordana D., Jakovljević, Dragica M., Lončarević, Branka D., Todorović, Nevena M., Pergal, Marija V., Ćirić, J., Loos, K., Beškoski, Vladimir, Vrvić, Miroslav M., "Production of levan by Bacillus licheniformis NS032 in sugar beet molasses-based medium" in International Journal of Biological Macromolecules, 121 (2019):142-151,
https://doi.org/10.1016/j.ijbiomac.2018.10.019 .,
Kon_1321 .
26
21
27

Lipid composition and DPPH activities of the seed oil of five Turkish hazelnut genotypes (Corylus colurna L.)

Ninić-Todorović, Jelena; Novaković, Miroslav M.; Čukanović, Jelena; Sofrenić, Ivana V.; Todorović, Ivan; Todorović, Dragan; Tešević, Vele

(2019)

TY  - JOUR
AU  - Ninić-Todorović, Jelena
AU  - Novaković, Miroslav M.
AU  - Čukanović, Jelena
AU  - Sofrenić, Ivana V.
AU  - Todorović, Ivan
AU  - Todorović, Dragan
AU  - Tešević, Vele
PY  - 2019
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3929
AB  - Five genotypes of Turkish hazelnuts (Corylus colurna L.) were analyzed for chemical composition, including total oil content, fatty acid and sterol composition. The oil yields from these kernels varied from 36.5% to 60.8% and the main fatty acids were oleic acid (79.34-83.0%) and linoleic acid (7.52-10.81%). The polyunsaturated/saturated fatty acid ratio was low, ranging from 0.87 to 1.25. To-tal phytosterol content ranged from 4.52 to 6.50 mg g -1 of oil. Among the eleven sterols identified and quantified, b-sitosterol was the major one with a mean percentage of 65.09% while fucosterol and campesterol were the second and the third components of the group with mean values of 10.91% and 4.36%, respectively. The radical scavenging activity was evaluated using 2.2-diphenyl-1 picrylhy-drazyl (DPPH) assay.
T2  - Lekovite sirovine
T1  - Lipid composition and DPPH activities of the seed oil of five Turkish hazelnut genotypes (Corylus colurna L.)
IS  - 39
SP  - 18
EP  - 22
DO  - 10.5937/leksir1939018N
ER  - 
@article{
author = "Ninić-Todorović, Jelena and Novaković, Miroslav M. and Čukanović, Jelena and Sofrenić, Ivana V. and Todorović, Ivan and Todorović, Dragan and Tešević, Vele",
year = "2019",
abstract = "Five genotypes of Turkish hazelnuts (Corylus colurna L.) were analyzed for chemical composition, including total oil content, fatty acid and sterol composition. The oil yields from these kernels varied from 36.5% to 60.8% and the main fatty acids were oleic acid (79.34-83.0%) and linoleic acid (7.52-10.81%). The polyunsaturated/saturated fatty acid ratio was low, ranging from 0.87 to 1.25. To-tal phytosterol content ranged from 4.52 to 6.50 mg g -1 of oil. Among the eleven sterols identified and quantified, b-sitosterol was the major one with a mean percentage of 65.09% while fucosterol and campesterol were the second and the third components of the group with mean values of 10.91% and 4.36%, respectively. The radical scavenging activity was evaluated using 2.2-diphenyl-1 picrylhy-drazyl (DPPH) assay.",
journal = "Lekovite sirovine",
title = "Lipid composition and DPPH activities of the seed oil of five Turkish hazelnut genotypes (Corylus colurna L.)",
number = "39",
pages = "18-22",
doi = "10.5937/leksir1939018N"
}
Ninić-Todorović, J., Novaković, M. M., Čukanović, J., Sofrenić, I. V., Todorović, I., Todorović, D.,& Tešević, V.. (2019). Lipid composition and DPPH activities of the seed oil of five Turkish hazelnut genotypes (Corylus colurna L.). in Lekovite sirovine(39), 18-22.
https://doi.org/10.5937/leksir1939018N
Ninić-Todorović J, Novaković MM, Čukanović J, Sofrenić IV, Todorović I, Todorović D, Tešević V. Lipid composition and DPPH activities of the seed oil of five Turkish hazelnut genotypes (Corylus colurna L.). in Lekovite sirovine. 2019;(39):18-22.
doi:10.5937/leksir1939018N .
Ninić-Todorović, Jelena, Novaković, Miroslav M., Čukanović, Jelena, Sofrenić, Ivana V., Todorović, Ivan, Todorović, Dragan, Tešević, Vele, "Lipid composition and DPPH activities of the seed oil of five Turkish hazelnut genotypes (Corylus colurna L.)" in Lekovite sirovine, no. 39 (2019):18-22,
https://doi.org/10.5937/leksir1939018N . .